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Richard Spaete

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John V Williams; Kathryn M Edwards; Geoffrey A Weinberg; Marie R Griffin; Caroline B Hall; Yuwei Zhu; Peter G Szilagyi; Chiaoyin K Wang; Chin-Fen Yang; David Silva; Dan Ye; Richard Spaete; James Crowe
Population-based incidence of human metapneumovirus infection among hospitalized children.
Chin-Fen Yang; Chiaoyin K Wang; Sharon J Tollefson; Rohith Piyaratna; Linda D Lintao; Marla Chu; Alexis Liem; Mary Mark; Richard Spaete; James Crowe; John V Williams
Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years.
Roderick S Tang; Richard Spaete; Mark W Thompson; Mia M MacPhail; Jeanne M Guzzetta; Patricia C Ryan; Keith S Reisinger; Patricia Chandler; Milo Hilty; Robert E Walker; Margarita Gomez; Genevieve A Losonsky
Development of a PIV-vectored RSV vaccine: preclinical evaluation of safety, toxicity, and enhanced disease and initial clinical testing in healthy adults.

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2010: John V Williams; Kathryn M Edwards; Geoffrey A Weinberg; Marie R Griffin; Caroline B Hall; Yuwei Zhu; Peter G Szilagyi; Chiaoyin K Wang; Chin-Fen Yang; David Silva; Dan Ye; Richard Spaete; James Crowe
Population-based incidence of human metapneumovirus infection among hospitalized children.
The Journal of infectious diseases 2010;201(12):1890-8.
2009: Chin-Fen Yang; Chiaoyin K Wang; Sharon J Tollefson; Rohith Piyaratna; Linda D Lintao; Marla Chu; Alexis Liem; Mary Mark; Richard Spaete; James Crowe; John V Williams
Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years.
Virology journal 2009;6():138.
2008: Roderick S Tang; Richard Spaete; Mark W Thompson; Mia M MacPhail; Jeanne M Guzzetta; Patricia C Ryan; Keith S Reisinger; Patricia Chandler; Milo Hilty; Robert E Walker; Margarita Gomez; Genevieve A Losonsky
Development of a PIV-vectored RSV vaccine: preclinical evaluation of safety, toxicity, and enhanced disease and initial clinical testing in healthy adults.
Vaccine 2008;26(50):6373-82.
2008: Jasmine Kaur; Roderick S Tang; Richard Spaete; Jeanne H Schickli
Optimization of plasmid-only rescue of highly attenuated and temperature-sensitive respiratory syncytial virus (RSV) vaccine candidates for human trials.
Journal of virological methods 2008;153(2):196-202.
2008: Jeanne H Schickli; Jasmine Kaur; Mia M MacPhail; Jeanne M Guzzetta; Richard Spaete; Roderick S Tang
Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters.
Virology journal 2008;5():69.
2006: Thomas C Heineman; Mark R Schleiss; David I Bernstein; Richard Spaete; Lihan Yan; Gregory M Duke; Mark Prichard; Zhaoti Wang; Qing Yan; Margaret A Sharp; Nicola Klein; Ann M Arvin; George W Kemble
A phase 1 study of 4 live, recombinant human cytomegalovirus Towne/Toledo chimeric vaccines.
The Journal of infectious diseases 2006;193(10):1350-60.
2006: Deborah A Buonagurio; Thomas M Bechert; Chin-Fen Yang; Leonid Shutyak; Gail A D'Arco; Yuriy Kazachkov; Hai-Ping Wang; Eduardo A Rojas; Robert E O'Neill; Richard Spaete; Kathleen L Coelingh; Timothy J Zamb; Maninder Sidhu; Stephen A Udem
Genetic stability of live, cold-adapted influenza virus components of the FluMist/CAIV-T vaccine throughout the manufacturing process.
Vaccine 2006;24(12):2151-60.
2006: John V Williams; Chiaoyin K Wang; Chin-Fen Yang; Sharon J Tollefson; Frances House; Josh M Heck; Marla Chu; Jennifer B Brown; Linda D Lintao; Joseph D Quinto; David Chu; Richard Spaete; Kathryn M Edwards; Peter F Wright; James Crowe
The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience.
The Journal of infectious diseases 2006;193(3):387-95.
2005: Mark Prichard; Ravi Kaiwar; Winthrop T Jackman; Debra C Quenelle; Deborah J Collins; Earl R Kern; George W Kemble; Richard Spaete
Evaluation of AD472, a live attenuated recombinant herpes simplex virus type 2 vaccine in guinea pigs.
Vaccine 2005;23(46-47):5424-31.
2005: Jeanne H Schickli; Jasmine Kaur; Nancy D Ulbrandt; Richard Spaete; Roderick S Tang
An S101P substitution in the putative cleavage motif of the human metapneumovirus fusion protein is a major determinant for trypsin-independent growth in vero cells and does not alter tissue tropism in hamsters.
Journal of virology 2005;79(16):10678-89.
2005: Roderick S Tang; Kutubuddin Mahmood; Mia M MacPhail; Jeanne M Guzzetta; Aurelia A Haller; Hui Liu; Jasmine Kaur; Heather A Lawlor; Elizabeth A Stillman; Jeanne H Schickli; Ron A M Fouchier; Albert D M E Osterhaus; Richard Spaete
A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys.
Vaccine 2005;23(14):1657-67.
2004: Roderick S Tang; Mia M MacPhail; Jeanne H Schickli; Jasmine Kaur; Christopher L Robinson; Heather A Lawlor; Jeanne M Guzzetta; Richard Spaete; Aurelia A Haller
Parainfluenza virus type 3 expressing the native or soluble fusion (F) Protein of Respiratory Syncytial Virus (RSV) confers protection from RSV infection in African green monkeys.
Journal of virology 2004;78(20):11198-207.
2004: Sander Herfst; Miranda de Graaf; Jeanne H Schickli; Roderick S Tang; Jasmine Kaur; Chin-Fen Yang; Richard Spaete; Aurelia A Haller; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Recovery of human metapneumovirus genetic lineages a and B from cloned cDNA.
Journal of virology 2004;78(15):8264-70.
2004: Mia M MacPhail; Jeanne H Schickli; Roderick S Tang; Jasmine Kaur; Christopher L Robinson; Ron A M Fouchier; Albert D M E Osterhaus; Richard Spaete; Aurelia A Haller
Identification of small-animal and primate models for evaluation of vaccine candidates for human metapneumovirus (hMPV) and implications for hMPV vaccine design.
The Journal of general virology 2004;85(Pt 6):1655-63.
2004: Jeroen Maertzdorf; Chiaoyin K Wang; Jennifer B Brown; Joseph D Quinto; Marla Chu; Miranda de Graaf; Bernadette van den Hoogen; Richard Spaete; Albert D M E Osterhaus; Ron A M Fouchier
Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages.
Journal of clinical microbiology 2004;42(3):981-6.
2003: Roderick S Tang; Jeanne H Schickli; Mia M MacPhail; Fiona Fernandes; Leenas Bicha; Joshua Spaete; Ron A M Fouchier; Albert D M E Osterhaus; Richard Spaete; Aurelia A Haller
Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3' proximal genome positions of bovine/human parainfluenza virus type 3 on virus replication and immunogenicity.
Journal of virology 2003;77(20):10819-28.
2001: Mark Prichard; Mark E T Penfold; Gregory M Duke; Richard Spaete; George W Kemble
A review of genetic differences between limited and extensively passaged human cytomegalovirus strains.
Reviews in medical virology 2001;11(3):191-200.
2000: George W Kemble; Paula Annunziato; Octavian Lungu; R E Winter; TA Cha; Saul J Silverstein; Richard Spaete
Open reading frame S/L of varicella-zoster virus encodes a cytoplasmic protein expressed in infected cells.
Journal of virology 2000;74(23):11311-21.
1999: Winthrop T Jackman; K A Mann; H J Hoffmann; Richard Spaete
Expression of Epstein-Barr virus gp350 as a single chain glycoprotein for an EBV subunit vaccine.
Vaccine 1999;17(7-8):660-8.
1998: F C Spector; Earl R Kern; J Palmer; Ravi Kaiwar; TA Cha; P Brown; Richard Spaete
Evaluation of a live attenuated recombinant virus RAV 9395 as a herpes simplex virus type 2 vaccine in guinea pigs.
The Journal of infectious diseases 1998;177(5):1143-54.
1996: George W Kemble; Gregory M Duke; R Winter; Richard Spaete
Defined large-scale alterations of the human cytomegalovirus genome constructed by cotransfection of overlapping cosmids.
Journal of virology 1996;70(3):2044-8.
1996: T A Cha; Ed Tom; George W Kemble; Gregory M Duke; Edward Mocarski; Richard Spaete
Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.
Journal of virology 1996;70(1):78-83.
1994: Richard Spaete; R C Gehrz; M P Landini
Human cytomegalovirus structural proteins.
The Journal of general virology 1994;75 ( Pt 12)():3287-308.
1993: David Chien; Q L Choo; R Ralston; Richard Spaete; M Tong; Michael Houghton; G Kuo
Persistence of HCV despite antibodies to both putative envelope glycoproteins.
Lancet 1993;342(8876):933.
1993: Richard Spaete; K Perot; P I Scott; Jay A Nelson; M F Stinski; C Pachl
Coexpression of truncated human cytomegalovirus gH with the UL115 gene product or the truncated human fibroblast growth factor receptor results in transport of gH to the cell surface.
Virology 1993;193(2):853-61.
1992: K Perot; C M Walker; Richard Spaete
Primary chimpanzee skin fibroblast cells are fully permissive for human cytomegalovirus replication.
The Journal of general virology 1992;73 ( Pt 12)():3281-4.
1992: B J Yoo; Richard Spaete; Adam P Geballe; Mark Selby; Michael Houghton; J H Han
5' end-dependent translation initiation of hepatitis C viral RNA and the presence of putative positive and negative translational control elements within the 5' untranslated region.
Virology 1992;191(2):889-99.
1992: Richard Spaete; D Alexander; M E Rugroden; Q L Choo; K Berger; K Crawford; C Kuo; S Leng; C Lee; R Ralston
Characterization of the hepatitis C virus E2/NS1 gene product expressed in mammalian cells.
Virology 1992;188(2):819-30.
1991: Lucy Rasmussen; CC Matkin; Richard Spaete; C Pachl; Thomas C Merigan
Antibody response to human cytomegalovirus glycoproteins gB and gH after natural infection in humans.
The Journal of infectious diseases 1991;164(5):835-42.
1991: Richard Spaete
A recombinant subunit vaccine approach to HCMV vaccine development.
Transplantation proceedings 1991;23(3 Suppl 3):90-6.
1990: Richard Spaete; A Saxena; P I Scott; G J Song; W S Probert; W J Britt; D GIBSON; L Rasmussen; C Pachl
Sequence requirements for proteolytic processing of glycoprotein B of human cytomegalovirus strain Towne.
Journal of virology 1990;64(6):2922-31.
1989: C Pachl; W S Probert; K M Hermsen; F R Masiarz; L Rasmussen; T C Merigan; Richard Spaete
The human cytomegalovirus strain Towne glycoprotein H gene encodes glycoprotein p86.
Virology 1989;169(2):418-26.
1989: T Banks; B Huo; K Kousoulas; Richard Spaete; C Pachl; L Pereira
A major neutralizing domain maps within the carboxyl-terminal half of the cleaved cytomegalovirus B glycoprotein.
The Journal of general virology 1989;70 ( Pt 4)():979-85.
1988: Richard Spaete; R M Thayer; W S Probert; F R Masiarz; S H Chamberlain; L Rasmussen; T C Merigan; C Pachl
Human cytomegalovirus strain Towne glycoprotein B is processed by proteolytic cleavage.
Virology 1988;167(1):207-25.
1987: Richard Spaete; Edward Mocarski
Insertion and deletion mutagenesis of the human cytomegalovirus genome.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(20):7213-7.
1987: Edward Mocarski; A C Liu; Richard Spaete
Structure and variability of the a sequence in the genome of human cytomegalovirus (Towne strain).
The Journal of general virology 1987;68 ( Pt 8)():2223-30.
1986: Adam P Geballe; Richard Spaete; Edward Mocarski
A cis-acting element within the 5' leader of a cytomegalovirus beta transcript determines kinetic class.
Cell 1986;46(6):865-72.
1985: Richard Spaete; Edward Mocarski
Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts.
Journal of virology 1985;56(1):135-43.
1985: Richard Spaete; Edward Mocarski
The alpha sequence of the cytomegalovirus genome functions as a cleavage/packaging signal for herpes simplex virus defective genomes.
Journal of virology 1985;54(3):817-24.
1985: Richard Spaete; N Frenkel
The herpes simplex virus amplicon: analyses of cis-acting replication functions.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(3):694-8.
1982: Richard Spaete; N Frenkel
The herpes simplex virus amplicon: a new eucaryotic defective-virus cloning-amplifying vector.
Cell 1982;30(1):295-304.