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Markku Seppala

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

Pregnancy

Procedures

Anatomy

Disorders

Uterine Neoplasms

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Publications

TOP 3
Chung Man-Kin; Chiu Philip C N; Lee Cheuk-Lun; Pang Ronald T K; Ng E H Y; Lee Kai-Fai; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Yeung William S B
Cumulus-associated alpha2-macroglobulin derivative retains proconceptive glycodelin-C in the human cumulus matrix.
Lam Kevin K W; Chiu Philip C N; Chung Man-Kin; Lee Cheuk-Lun; Lee Kai-Fai; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Ho Pak-Chung; Yeung William S B
Glycodelin-A as a modulator of trophoblast invasion.
Lee Cheuk-Lun; Pang Poh-Choo; Yeung William S B; Tissot Bérangère; Panico Maria; Lao Terence T H; Chu Ivan K; Lee Kai-Fai; Chung Man-Kin; Lam Kevin K W; Koistinen Riitta; Koistinen Hannu; Seppälä Markku; Morris Howard R; Dell Anne; Chiu Philip C N
Effects of differential glycosylation of glycodelins on lymphocyte survival.

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All Publications

2009: Chung Man-Kin; Chiu Philip C N; Lee Cheuk-Lun; Pang Ronald T K; Ng E H Y; Lee Kai-Fai; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Yeung William S B
Cumulus-associated alpha2-macroglobulin derivative retains proconceptive glycodelin-C in the human cumulus matrix.
Human reproduction (Oxford, England) 2009;24(11):2856-67.
2009: Lam Kevin K W; Chiu Philip C N; Chung Man-Kin; Lee Cheuk-Lun; Lee Kai-Fai; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Ho Pak-Chung; Yeung William S B
Glycodelin-A as a modulator of trophoblast invasion.
Human reproduction (Oxford, England) 2009;24(9):2093-103.
2009: Lee Cheuk-Lun; Pang Poh-Choo; Yeung William S B; Tissot Bérangère; Panico Maria; Lao Terence T H; Chu Ivan K; Lee Kai-Fai; Chung Man-Kin; Lam Kevin K W; Koistinen Riitta; Koistinen Hannu; Seppälä Markku; Morris Howard R; Dell Anne; Chiu Philip C N
Effects of differential glycosylation of glycodelins on lymphocyte survival.
The Journal of biological chemistry 2009;284(22):15084-96.
2009: Seppälä M; Koistinen H; Koistinen R; Hautala L; Chiu P C; Yeung W S
Glycodelin in reproductive endocrinology and hormone-related cancer.
European journal of endocrinology / European Federation of Endocrine Societies 2009;160(2):121-33.
2009: Koistinen Hannu; Hautala Laura C; Seppälä Markku; Stenman Ulf-Håkan; Laakkonen Pirjo; Koistinen Riitta
The role of glycodelin in cell differentiation and tumor growth.
Scandinavian journal of clinical and laboratory investigation 2009;69(4):452-9.
2008: Hautala Laura C; Koistinen Riitta; Seppälä Markku; Bützow Ralf; Stenman Ulf-Håkan; Laakkonen Pirjo; Koistinen Hannu
Glycodelin reduces breast cancer xenograft growth in vivo.
International journal of cancer. Journal international du cancer 2008;123(10):2279-84.
2007: do Nascimento Josiane A A; Seppala Markku; Perdigão Antero; Espejo-Arce Ximena; Munuce Maria José; Hautala Laura; Koistinen Riitta; Andrade Liliana; Bahamondes Luis
In vivo assessment of the human sperm acrosome reaction and the expression of glycodelin-A in human endometrium after levonorgestrel-emergency contraceptive pill administration.
Human reproduction (Oxford, England) 2007;22(8):2190-5.
2007: Seppälä M; Koistinen H; Koistinen R; Chiu P C N; Yeung W S B
Glycosylation related actions of glycodelin: gamete, cumulus cell, immune cell and clinical associations.
Human reproduction update 2007;13(3):275-87.
2007: Chiu Philip C N; Chung Man-Kin; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Ho Pak-Chung; Ng Ernest H Y; Lee Kai-Fai; Yeung William S B
Cumulus oophorus-associated glycodelin-C displaces sperm-bound glycodelin-A and -F and stimulates spermatozoa-zona pellucida binding.
The Journal of biological chemistry 2007;282(8):5378-88.
2007: Chiu Philip C N; Chung Man-Kin; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Ho Pak-Chung; Ng Ernest H Y; Lee Kai-Fai; Yeung William S B
Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding.
Journal of cell science 2007;120(Pt 1):33-44.
2007: Seppälä Markku; Koistinen Hannu; Koistinen Riitta; Chiu Philip C N; Yeung William S B
[Not Available]
Duodecim; lääketieteellinen aikakauskirja 2007;123(14):1670-2.
2007: Yeung William S B; Lee Kai-Fai; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Ho P C; Chiu Philip C N
Glycodelin: a molecule with multi-functions on spermatozoa.
Society of Reproduction and Fertility supplement 2007;63():143-51.
2006: Koistinen Hannu; Seppälä Markku; Knuutila Sakari; Koistinen Riitta
Extracellular matrix-induced changes in expression of cell cycle-related proteins and proteasome components in endometrial adenocarcinoma cells.
Gynecologic oncology 2006;102(3):546-51.
2006: Stavreus-Evers Anneli; Mandelin Erik; Koistinen Riitta; Aghajanova Lusine; Hovatta Outi; Seppälä Markku
Glycodelin is present in pinopodes of receptive-phase human endometrium and is associated with down-regulation of progesterone receptor B.
Fertility and sterility 2006;85(6):1803-11.
2006: Yeung William S B; Lee Kai-Fai; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Ho P C; Chiu Philip C N
Roles of glycodelin in modulating sperm function.
Molecular and cellular endocrinology 2006;250(1-2):149-56.
2006: Seppälä Markku; Koistinen Hannu; Koistinen Riitta; Chiu Philip C N; Yeung William S
[Not Available]
Duodecim; lääketieteellinen aikakauskirja 2006;122(12):1439-44.
2005: Koistinen Hannu; Seppälä Markku; Nagy Balint; Tapper Johanna; Knuutila Sakari; Koistinen Riitta
Glycodelin reduces carcinoma-associated gene expression in endometrial adenocarcinoma cells.
American journal of obstetrics and gynecology 2005;193(6):1955-60.
2005: Chiu Philip C N; Chung Man-Kin; Tsang Heng-Yan; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Lee Kai-Fai; Yeung William S B
Glycodelin-S in human seminal plasma reduces cholesterol efflux and inhibits capacitation of spermatozoa.
The Journal of biological chemistry 2005;280(27):25580-9.
2005: Durand Marta; Seppala Markku; Cravioto Ma Del Carmen; Koistinen Hannu; Koistinen Riitta; González-Macedo José; Larrea Fernando
Late follicular phase administration of levonorgestrel as an emergency contraceptive changes the secretory pattern of glycodelin in serum and endometrium during the luteal phase of the menstrual cycle.
Contraception 2005;71(6):451-7.
2005: Seppälä Markku; Mandelin Erik; Koistinen Riitta; Bergholm Robert; Tiikkainen Mirja; Yki-Järvinen Hannele
Glycodelin responses to hyperinsulinaemic clamp vary according to basal serum glycodelin concentration.
Clinical endocrinology 2005;62(5):611-5.
2005: Kalme Tarja; Seppälä Markku; Qiao Qing; Koistinen Riitta; Nissinen Aulikki; Harrela Maija; Loukovaara Mikko; Leinonen Pekka; Tuomilehto Jaakko
Sex hormone-binding globulin and insulin-like growth factor-binding protein-1 as indicators of metabolic syndrome, cardiovascular risk, and mortality in elderly men.
The Journal of clinical endocrinology and metabolism 2005;90(3):1550-6.
2004: Seppälä M
FIGO's Constitution and Bye-Laws.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2004;86(2):190-201.
2004: Chiu P C N; Tsang H Y; Koistinen R; Koistinen H; Seppala M; Lee K F; Yeung W S B
The contribution of D-mannose, L-fucose, N-acetylglucosamine, and selectin residues on the binding of glycodelin isoforms to human spermatozoa.
Biology of reproduction 2004;70(6):1710-9.
2004: Seppälä M
Advances in uterine protein research: reproduction and cancer.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2004;85(2):105-18.
2004: Jakubowicz Daniela J; Essah Paulina A; Seppälä Markku; Jakubowicz Salomon; Baillargeon Jean-Patrice; Koistinen Riitta; Nestler John E
Reduced serum glycodelin and insulin-like growth factor-binding protein-1 in women with polycystic ovary syndrome during first trimester of pregnancy.
The Journal of clinical endocrinology and metabolism 2004;89(2):833-9.
2003: Koistinen Hannu; Easton Richard L; Chiu Philip C N; Chalabi Sara; Halttunen Mervi; Dell Anne; Morris Howard R; Yeung William S B; Seppala Markku; Koistinen Riitta
Differences in glycosylation and sperm-egg binding inhibition of pregnancy-related glycodelin.
Biology of reproduction 2003;69(5):1545-51.
2003: Mandelin Erik; Lassus Heini; Seppälä Markku; Leminen Arto; Gustafsson Jan-Ake; Cheng Guojun; Bützow Ralf; Koistinen Riitta
Glycodelin in ovarian serous carcinoma: association with differentiation and survival.
Cancer research 2003;63(19):6258-64.
2003: Chiu P C N; Koistinen R; Koistinen H; Seppala M; Lee K F; Yeung W S B
Zona-binding inhibitory factor-1 from human follicular fluid is an isoform of glycodelin.
Biology of reproduction 2003;69(1):365-72.
2003: Chiu Philip C N; Koistinen Riitta; Koistinen Hannu; Seppala Markku; Lee Kai-Fai; Yeung William S B
Binding of zona binding inhibitory factor-1 (ZIF-1) from human follicular fluid on spermatozoa.
The Journal of biological chemistry 2003;278(15):13570-7.
2003: Kajantie Eero; Fall Caroline H D; Seppälä Markku; Koistinen Riitta; Dunkel Leo; Ylihärsilä Hilkka; Osmond Clive; Andersson Sture; Barker David J P; Forsén Tom; Holt Richard I G; Phillips David I W; Eriksson Johan
Serum insulin-like growth factor (IGF)-I and IGF-binding protein-1 in elderly people: relationships with cardiovascular risk factors, body composition, size at birth, and childhood growth.
The Journal of clinical endocrinology and metabolism 2003;88(3):1059-65.
2002: Loukovaara Mikko; Koistinen Riitta; Kalme Tarja; Kurki Tapio; Leinonen Pekka; Seppälä Markku
Serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 in premature rupture of membranes.
Acta obstetricia et gynecologica Scandinavica 2002;81(10):905-8.
2002: Seppälä Markku; Taylor Robert N; Koistinen Hannu; Koistinen Riitta; Milgrom Edwin
Glycodelin: a major lipocalin protein of the reproductive axis with diverse actions in cell recognition and differentiation.
Endocrine reviews 2002;23(4):401-30.
2002: Kajantie Eero; Dunkel Leo; Rutanen Eeva-Marja; Seppälä Markku; Koistinen Riitta; Sarnesto Annikki; Andersson Sture
IGF-I, IGF binding protein (IGFBP)-3, phosphoisoforms of IGFBP-1, and postnatal growth in very low birth weight infants.
The Journal of clinical endocrinology and metabolism 2002;87(5):2171-9.
2002: Harrela M; Qiao Q; Koistinen R; Tuomilehto J; Nissinen A; Seppälä M; Leinonen P
High serum insulin-like growth factor binding protein-1 is associated with increased cardiovascular mortality in elderly men.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(3):144-9.
2002: Koistinen Hannu; Soini Tuuli; Leinonen Jari; Hyden-Granskog Christel; Salo Jaakko; Halttunen Mervi; Stenman Ulf-Håkan; Seppälä Markku; Koistinen Riitta
Monoclonal antibodies, immunofluorometric assay, and detection of human semenogelin in male reproductive tract: no association with in vitro fertilizing capacity of sperm.
Biology of reproduction 2002;66(3):624-8.
2002: Tse J Y M; Chiu P C N; Lee K F; Seppala M; Koistinen H; Koistinen R; Yao Y Q; Yeung W S B
The synthesis and fate of glycodelin in human ovary during folliculogenesis.
Molecular human reproduction 2002;8(2):142-8.
2002: Koistinen Hannu; Paju Annukka; Koistinen Riitta; Finne Patrik; Lövgren Janita; Wu Ping; Seppälä Markku; Stenman Ulf-Håkan
Prostate-specific antigen and other prostate-derived proteases cleave IGFBP-3, but prostate cancer is not associated with proteolytically cleaved circulating IGFBP-3.
The Prostate 2002;50(2):112-8.
2002: Arnold Julia T; Lessey Bruce A; Seppälä Markku; Kaufman David G
Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells.
Cancer research 2002;62(1):79-88.
2002: Loukovaara Mikko; Koistinen Riitta; Kurki Tapio; Seppälä Markku
Maternal serum glycodelin in premature rupture of membranes.
Journal of perinatal medicine 2002;30(6):480-2.
2001: Niemimaa M; Heinonen S; Seppälä M; Hippeläinen M; Martikainen H; Ryynänen M
First-trimester screening for Down's syndrome in in vitro fertilization pregnancies.
Fertility and sterility 2001;76(6):1282-3.
2001: Mandelin E; Koistinen H; Koistinen R; Arola J; Affandi B; Seppälä M
Endometrial expression of glycodelin in women with levonorgestrel-releasing subdermal implants.
Fertility and sterility 2001;76(3):474-8.
2001: Damario M A; Lesnick T G; Lessey B A; Kowalik A; Mandelin E; Seppälä M; Rosenwaks Z
Endometrial markers of uterine receptivity utilizing the donor oocyte model.
Human reproduction (Oxford, England) 2001;16(9):1893-9.
2001: Kalme T; Loukovaara M; Koistinen H; Koistinen R; Seppälä M; Leinonen P
Factors regulating insulin-like growth factor binding protein-3 secretion from human hepatoma (HepG2) cells.
The Journal of steroid biochemistry and molecular biology 2001;78(2):131-5.
2001: Tapper J; Kettunen E; El-Rifai W; Seppälä M; Andersson L C; Knuutila S
Changes in gene expression during progression of ovarian carcinoma.
Cancer genetics and cytogenetics 2001;128(1):1-6.
2001: Gao J; Mazella J; Seppala M; Tseng L
Ligand activated hPR modulates the glycodelin promoter activity through the Sp1 sites in human endometrial adenocarcinoma cells.
Molecular and cellular endocrinology 2001;176(1-2):97-102.
2001: Arnold J T; Kaufman D G; Seppälä M; Lessey B A
Endometrial stromal cells regulate epithelial cell growth in vitro: a new co-culture model.
Human reproduction (Oxford, England) 2001;16(5):836-45.
2001: Seppälä M; Koistinen H; Koistinen R
Glycodelins.
Trends in endocrinology and metabolism: TEM 2001;12(3):111-7.
2001: Kajantie E; Hytinantti T; Koistinen R; Risteli J; Rutanen E M; Seppälä M; Andersson S
Markers of type I and type III collagen turnover, insulin-like growth factors, and their binding proteins in cord plasma of small premature infants: relationships with fetal growth, gestational age, preeclampsia, and antenatal glucocorticoid treatment.
Pediatric research 2001;49(4):481-9.
2001: Jakubowicz D J; Seppälä M; Jakubowicz S; Rodriguez-Armas O; Rivas-Santiago A; Koistinen H; Koistinen R; Nestler J E
Insulin reduction with metformin increases luteal phase serum glycodelin and insulin-like growth factor-binding protein 1 concentrations and enhances uterine vascularity and blood flow in the polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism 2001;86(3):1126-33.
2000: Raymond E G; Lovely L P; Chen-Mok M; Seppälä M; Kurman R J; Lessey B A
Effect of the Yuzpe regimen of emergency contraception on markers of endometrial receptivity.
Human reproduction (Oxford, England) 2000;15(11):2351-5.
2000: Harrela M; Koistinen R; Tuomilehto J; Nissinen A; Seppälä M
Low serum insulin-like growth factor-binding protein-1 is associated with an unfavourable cardiovascular risk profile in elderly men.
Annals of medicine 2000;32(6):424-8.
2000: Bützow T L; Lehtovirta M; Siegberg R; Hovatta O; Koistinen R; Seppäla M; Apter D
The decrease in luteinizing hormone secretion in response to weight reduction is inversely related to the severity of insulin resistance in overweight women.
The Journal of clinical endocrinology and metabolism 2000;85(9):3271-5.
2000: Koistinen H; Koistinen R; Hydén-Granskog C; Magnus O; Seppälä M
Seminal plasma glycodelin and fertilization in vitro.
Journal of andrology 2000;21(5):636-40.
2000: Finne P; Auvinen A; Koistinen H; Zhang W M; Määttänen L; Rannikko S; Tammela T; Seppälä M; Hakama M; Stenman U H
Insulin-like growth factor I is not a useful marker of prostate cancer in men with elevated levels of prostate-specific antigen.
The Journal of clinical endocrinology and metabolism 2000;85(8):2744-7.
2000: Brown S E; Mandelin E; Oehninger S; Toner J P; Seppala M; Jones H W
Histochemical localization of endometrial insulin-like growth factor binding protein-1 and -3 during the luteal phase in controlled ovarian hyperstimulation cycles: a controlled study.
Fertility and sterility 2000;74(2):338-42.
2000: Van den Nieuwenhof I M; Koistinen H; Easton R L; Koistinen R; Kämäräinen M; Morris H R; Van Die I; Seppälä M; Dell A; Van den Eijnden D H
Recombinant glycodelin carrying the same type of glycan structures as contraceptive glycodelin-A can be produced in human kidney 293 cells but not in chinese hamster ovary cells.
European journal of biochemistry / FEBS 2000;267(15):4753-62.
2000: Brown S E; Mandelin E; Oehninger S; Toner J P; Seppala M; Jones H W
Endometrial glycodelin-A expression in the luteal phase of stimulated ovarian cycles.
Fertility and sterility 2000;74(1):130-3.
2000: Seppälä M
The role of FIGO in the advancement of women's health - in the year 2000.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2000;70(1):175-82.
1999: Kämäräinen M; Halttunen M; Koistinen R; von Boguslawsky K; von Smitten K; Andersson L C; Seppälä M
Expression of glycodelin in human breast and breast cancer.
International journal of cancer. Journal international du cancer 1999;83(6):738-42.
1999: Bernardi F; Petraglia F; Seppälä M; Spinetti A; Bertolini S; Driul L; Ferdeghini M; Genazzani A R
GH, IGFBP-1, and IGFBP-3 response to oral glucose tolerance test in perimenopausal women: no influence of body mass index.
Maturitas 1999;33(2):163-9.
1999: Kalme T; Loukovaara M; Koistinen R; Koistinen H; Angervo M; Leinonen P; Seppälä M
Estradiol increases the production of sex hormone-binding globulin but not insulin-like growth factor binding protein-1 in cultured human hepatoma cells.
Fertility and sterility 1999;72(2):325-9.
1999: Seppälä M
Glycodelins: biological activity in reproduction and differentiation.
Current opinion in obstetrics & gynecology 1999;11(3):261-3.
1999: Gersak K; Seppälä M; Us-Krasovec M
The same luteinized granulosa-luteal cells from normal and superovulated human chorionic gonadotropin (hCG)-stimulated cycles contain hCG and insulin-like growth factor binding protein-1.
Fertility and sterility 1999;71(5):902-6.
1999: Koistinen H; Koistinen R; Seppälä M; Burova T V; Choiset Y; Haertlé T
Glycodelin and beta-lactoglobulin, lipocalins with a high structural similarity, differ in ligand binding properties.
FEBS letters 1999;450(1-2):158-62.
1999: Tseng L; Zhu H H; Mazella J; Koistinen H; Seppälä M
Relaxin stimulates glycodelin mRNA and protein concentrations in human endometrial glandular epithelial cells.
Molecular human reproduction 1999;5(4):372-5.
1998: Taylor R N; Savouret J F; Vaisse C; Vigne J L; Ryan I; Hornung D; Seppälä M; Milgrom E
Promegestone (R5020) and mifepristone (RU486) both function as progestational agonists of human glycodelin gene expression in isolated human epithelial cells.
The Journal of clinical endocrinology and metabolism 1998;83(11):4006-12.
1998: Karila T; Koistinen H; Seppälä M; Koistinen R; Seppälä T
Growth hormone induced increase in serum IGFBP-3 level is reversed by anabolic steroids in substance abusing power athletes.
Clinical endocrinology 1998;49(4):459-63.
1998: Pere H; Tapper J; Seppälä M; Knuutila S; Butzow R
Genomic alterations in fallopian tube carcinoma: comparison to serous uterine and ovarian carcinomas reveals similarity suggesting likeness in molecular pathogenesis.
Cancer research 1998;58(19):4274-6.
1998: Oehninger S; Patankar M; Seppala M; Clark G F
Involvement of selectin-like carbohydrate binding specificity in human gamete interaction.
Andrologia 1998;30(4-5):269-74.
1998: Tapper J; Sarantaus L; Vahteristo P; Nevanlinna H; Hemmer S; Seppälä M; Knuutila S; Butzow R
Genetic changes in inherited and sporadic ovarian carcinomas by comparative genomic hybridization: extensive similarity except for a difference at chromosome 2q24-q32.
Cancer research 1998;58(13):2715-9.
1998: Seppälä M; Koistinen H; Koistinen R; Mandelin E; Oehninger S; Clark G F; Dell A; Morris H R
Glycodelins: role in regulation of reproduction, potential for contraceptive development and diagnosis of male infertility.
Human reproduction (Oxford, England) 1998;13 Suppl 3():262-9l; discussion 270.
1998: Kämäräinen M; Miettinen M; Seppala M; von Boguslawsky K; Benassi M S; Böhling T; Andersson L C
Epithelial expression of glycodelin in biphasic synovial sarcomas.
International journal of cancer. Journal international du cancer 1998;76(4):487-90.
1998: Bernardi F; Petraglia F; Seppala M; Spinetti A; Bertolini S; Ferdeghini M; Genazzani A R
Somatotropic axis and body weight in pre-menopausal and post-menopausal women: evidence for a neuroendocrine derangement, in absence of changes of insulin-like growth factor binding protein concentrations.
Human reproduction (Oxford, England) 1998;13(2):279-84.
1998: Seppälä M; Koistinen H; Mandelin E; Koistinen R
[Importance of uterus and sperm glycodelins in the regulation of reproduction]
Duodecim; lääketieteellinen aikakauskirja 1998;114(8):761-7.
1998: Seppälä M; Bohn H; Tatarinov Y
Glycodelins.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1998;19(3):213-20.
1997: Harrison K A; Seppälä M
Obstetrics and gynaecology. Women and market forces.
Lancet 1997;350 Suppl 3():SIII16.
1997: Mandelin E; Koistinen H; Koistinen R; Affandi B; Seppälä M
Levonorgestrel-releasing intrauterine device-wearing women express contraceptive glycodelin A in endometrium during midcycle: another contraceptive mechanism?
Human reproduction (Oxford, England) 1997;12(12):2671-5.
1997: Kämäräinen M; Seppälä M; Virtanen I; Andersson L C
Expression of glycodelin in MCF-7 breast cancer cells induces differentiation into organized acinar epithelium.
Laboratory investigation; a journal of technical methods and pathology 1997;77(6):565-73.
1997: Holst N; Kierulf K H; Seppälä M; Koistinen R; Jacobsen M B
Regulation of insulin-like growth factor-binding protein-1 and progesterone secretion from human granulosa-luteal cells: effects of octreotide and insulin.
Fertility and sterility 1997;68(3):478-82.
1997: Seppälä M; Jiang S; Strick N; Lin K; Li Y Y; Koistinen H; Koistinen R; Neurath A R
Glycodelins GdA and GdS modified by 3-hydroxyphthalic anhydride inhibit gp120-CD4 binding and HIV-1 infection in vitro.
Laboratory investigation; a journal of technical methods and pathology 1997;77(2):127-30.
1997: Patankar M S; Ozgur K; Oehninger S; Dell A; Morris H; Seppala M; Clark G F
Expression of glycans linked to natural killer cell inhibition on the human zona pellucida.
Molecular human reproduction 1997;3(6):501-5.
1997: Koistinen H; Koistinen R; Kämäräinen M; Salo J; Seppälä M
Multiple forms of messenger ribonucleic acid encoding glycodelin in male genital tract.
Laboratory investigation; a journal of technical methods and pathology 1997;76(5):683-90.
1997: Seppälä M; Koistinen H; Koistinen R; Dell A; Morris H R; Oehninger S; Clark G F
Glycodelins as regulators of early events of reproduction.
Clinical endocrinology 1997;46(4):381-6.
1997: Stewart D R; Erikson M S; Erikson M E; Nakajima S T; Overstreet J W; Lasley B L; Amento E P; Seppala M
The role of relaxin in glycodelin secretion.
The Journal of clinical endocrinology and metabolism 1997;82(3):839-46.
1997: Clark G F; Dell A; Morris H R; Patankar M; Oehninger S; Seppälä M
Viewing AIDS from a glycobiological perspective: potential linkages to the human fetoembryonic defence system hypothesis.
Molecular human reproduction 1997;3(1):5-13.
1997: Danielsson K G; Swahn M L; Westlund P; Johannisson E; Seppälä M; Bygdeman M
Effect of low daily doses of mifepristone on ovarian function and endometrial development.
Human reproduction (Oxford, England) 1997;12(1):124-31.
1997: Tapper J; Bützow R; Wahlström T; Seppälä M; Knuutila S
Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas.
British journal of cancer 1997;75(12):1782-7.
1996: Harrela M; Koistinen H; Kaprio J; Lehtovirta M; Tuomilehto J; Eriksson J; Toivanen L; Koskenvuo M; Leinonen P; Koistinen R; Seppälä M
Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3.
The Journal of clinical investigation 1996;98(11):2612-5.
1996: Morris H R; Dell A; Easton R L; Panico M; Koistinen H; Koistinen R; Oehninger S; Patankar M S; Seppala M; Clark G F
Gender-specific glycosylation of human glycodelin affects its contraceptive activity.
The Journal of biological chemistry 1996;271(50):32159-67.
1996: Koistinen H; Koistinen R; Dell A; Morris H R; Easton R L; Patankar M S; Oehninger S; Clark G F; Seppälä M
Glycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A.
Molecular human reproduction 1996;2(10):759-65.
1996: Clark G F; Oehninger S; Seppälä M
Role for glycoconjugates in cellular communication in the human reproductive system.
Molecular human reproduction 1996;2(7):513-7.
1996: Hahn R G; Olsson J; Englund K; Seppälä M
Serum levels of endometrial proteins during transcervical resection of the endometrium.
British journal of obstetrics and gynaecology 1996;103(5):442-5.
1996: Kämäräinen M; Leivo I; Koistinen R; Julkunen M; Karvonen U; Rutanen E M; Seppälä M
Normal human ovary and ovarian tumors express glycodelin, a glycoprotein with immunosuppressive and contraceptive properties.
The American journal of pathology 1996;148(5):1435-43.
1996: Suikkari A; MacLachlan V; Koistinen R; Seppälä M; Healy D
Double-blind placebo controlled study: human biosynthetic growth hormone for assisted reproductive technology.
Fertility and sterility 1996;65(4):800-5.
1996: Koistinen H; Koistinen R; Selenius L; Ylikorkala Q; Seppälä M
Effect of marathon run on serum IGF-I and IGF-binding protein 1 and 3 levels.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;80(3):760-4.
1996: Heinonen S; Ryynänen M; Kirkinen P; Penttilä I; Syrjänen K; Seppälä M; Saarikoski S
Prenatal screening for congenital nephrosis in east Finland: results and impact on the birth prevalence of the disease.
Prenatal diagnosis 1996;16(3):207-13.
1996: Clark G F; Oehninger S; Patankar M S; Koistinen R; Dell A; Morris H R; Koistinen H; Seppälä M
A role for glycoconjugates in human development: the human feto-embryonic defence system hypothesis.
Human reproduction (Oxford, England) 1996;11(3):467-73.
1996: Vihervuori E; Virtanen M; Koistinen H; Koistinen R; Seppälä M; Siimes M A
Hemoglobin level is linked to growth hormone-dependent proteins in short children.
Blood 1996;87(5):2075-81.
1996: Gemzell-Danielsson K; Westlund P; Johannisson E; Swahn M L; Bygdeman M; Seppälä M
Effect of low weekly doses of mifepristone on ovarian function and endometrial development.
Human reproduction (Oxford, England) 1996;11(2):256-64.
1996: Seppälä M; Tiitinen A; Teramo K; Raivio K
[Assisted reproduction and risks of superovulation]
Duodecim; lääketieteellinen aikakauskirja 1996;112(4):245-7.
1995: Seppälä M; Tiitinen A
Endometrial responses to corpus luteum products in cycles with induced ovulation: theoretical and practical considerations.
Human reproduction (Oxford, England) 1995;10 Suppl 2():67-76.
1995: Ebeling P; Stenman U H; Seppälä M; Koivisto V A
Androgens and insulin resistance in type 1 diabetic men.
Clinical endocrinology 1995;43(5):601-7.
1995: Dell A; Morris H R; Easton R L; Panico M; Patankar M; Oehniger S; Koistinen R; Koistinen H; Seppala M; Clark G F
Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities.
The Journal of biological chemistry 1995;270(41):24116-26.
1995: Hamilton-Fairley D; White D; Griffiths M; Anyaoku V; Koistinen R; Seppälä M; Franks S
Diurnal variation of sex hormone binding globulin and insulin-like growth factor binding protein-1 in women with polycystic ovary syndrome.
Clinical endocrinology 1995;43(2):159-65.
1995: Ebeling P; Stenman U H; Seppälä M; Koivisto V A
Acute hyperinsulinemia, androgen homeostasis and insulin sensitivity in healthy man.
The Journal of endocrinology 1995;146(1):63-9.
1995: Tulppala M; Julkunen M; Tiitinen A; Stenman U H; Seppälä M
Habitual abortion is accompanied by low serum levels of placental protein 14 in the luteal phase of the fertile cycle.
Fertility and sterility 1995;63(4):792-5.
1995: Tiitinen A; Husa L M; Tulppala M; Simberg N; Seppälä M
The effect of cryopreservation in prevention of ovarian hyperstimulation syndrome.
British journal of obstetrics and gynaecology 1995;102(4):326-9.
1995: Jahanfar S; Eden J A; Warren P; Seppälä M; Nguyen T V
A twin study of polycystic ovary syndrome.
Fertility and sterility 1995;63(3):478-86.
1995: Oehninger S; Coddington C C; Hodgen G D; Seppala M
Factors affecting fertilization: endometrial placental protein 14 reduces the capacity of human spermatozoa to bind to the human zona pellucida.
Fertility and sterility 1995;63(2):377-83.
1994: Morrow D M; Xiong N; Getty R R; Ratajczak M Z; Morgan D; Seppala M; Riittinen L; Gewirtz A M; Tykocinski M L
Hematopoietic placental protein 14. An immunosuppressive factor in cells of the megakaryocytic lineage.
The American journal of pathology 1994;145(6):1485-95.
1994: Miettinen T; Tiitinen A; Koistinen R; Julkunen M; Seppälä M
Serum placental protein 14 concentrations are similar in the first trimester pregnancies of women after pituitary down-regulation with a gonadotrophin-releasing hormone agonist and normal cycles with frozen embryo transfers.
Human reproduction (Oxford, England) 1994;9(12):2429-31.
1994: Anttila R; Koistinen R; Seppälä M; Koistinen H; Siimes M A
Insulin-like growth factor I and insulin-like growth factor binding protein 3 as determinants of blood hemoglobin concentration in healthy subjects.
Pediatric research 1994;36(6):745-8.
1994: Sarvas K; Angervo M; Koistinen R; Tiitinen A; Seppälä M
Prostaglandin F2 alpha stimulates release of insulin-like growth factor binding protein-3 from cultured human granulosa-luteal cells.
Human reproduction (Oxford, England) 1994;9(9):1643-6.
1994: Kämäräinen M; Riittinen L; Seppälä M; Palotie A; Andersson L C
Progesterone-associated endometrial protein--a constitutive marker of human erythroid precursors.
Blood 1994;84(2):467-73.
1994: Seppälä M; Koistinen R; Rutanen E M
Uterine endocrinology and paracrinology: insulin-like growth factor binding protein-1 and placental protein 14 revisited.
Human reproduction (Oxford, England) 1994;9(5):917-25.
1994: Koistinen H; Seppälä M; Koistinen R
Different forms of insulin-like growth factor-binding protein-3 detected in serum and seminal plasma by immunofluorometric assay with monoclonal antibodies.
Clinical chemistry 1994;40(4):531-6.
1994: Klentzeris L D; Bulmer J N; Seppälä M; Li T C; Warren M A; Cooke I D
Placental protein 14 in cycles with normal and retarded endometrial differentiation.
Human reproduction (Oxford, England) 1994;9(3):394-8.
1994: Insler V; Barash A; Shoham Z; Koistinen R; Seppala M; Hen M; Lunenfeld B; Zadik Z
Overnight secretion pattern of growth hormone, sex hormone binding globulin, insulin-like growth factor-1 and its binding protein in obese and non-obese women with polycystic ovarian disease.
Israel journal of medical sciences 1994;30(1):42-7.
1993: Seppälä M; Julkunen M; Rutanen E M
Endometrial protein secretion during the peri-implantation phase and early pregnancy.
Acta Europaea fertilitatis 1993;24(5):225-8.
1993: Hamilton-Fairley D; Kiddy D; Anyaoku V; Koistinen R; Seppälä M; Franks S
Response of sex hormone binding globulin and insulin-like growth factor binding protein-1 to an oral glucose tolerance test in obese women with polycystic ovary syndrome before and after calorie restriction.
Clinical endocrinology 1993;39(3):363-7.
1993: Tiitinen A; Tenhunen A; Seppälä M
Ovarian electrocauterization causes LH-regulated but not insulin-regulated endocrine changes.
Clinical endocrinology 1993;39(2):181-4.
1993: Hakala-Ala-Pietilä T H; Koistinen R A; Salonen R K; Seppälä M T
Elevated second-trimester amniotic fluid concentration of insulin-like growth factor binding protein-1 in fetal growth retardation.
American journal of obstetrics and gynecology 1993;169(1):35-9.
1993: Tiitinen A E; Laatikainen T J; Seppälä M T
Serum levels of insulin-like growth factor binding protein-1 and ovulatory responses to clomiphene citrate in women with polycystic ovarian disease.
Fertility and sterility 1993;60(1):58-62.
1993: Koistinen R; Angervo M; Leinonen P; Hakala T; Seppälä M
Phosphorylation of insulin-like growth factor-binding protein-1 increases in human amniotic fluid and decidua from early to late pregnancy.
Clinica chimica acta; international journal of clinical chemistry 1993;215(2):189-99.
1993: Angervo M; Tiihonen M; Leinonen P; Välimäki M; Seppälä M
Thyroxine treatment increases circulating levels of insulin-like growth factor binding protein-1: a placebo-controlled study.
Clinical endocrinology 1993;38(5):547-51.
1993: Mason H D; Margara R; Winston R M; Seppala M; Koistinen R; Franks S
Insulin-like growth factor-I (IGF-I) inhibits production of IGF-binding protein-1 while stimulating estradiol secretion in granulosa cells from normal and polycystic human ovaries.
The Journal of clinical endocrinology and metabolism 1993;76(5):1275-9.
1993: Angervo M; Toivonen J; Leinonen P; Välimäki M; Seppälä M
Thyroxine withdrawal is accompanied by decreased circulating levels of insulin-like growth factor-binding protein-1 in thyroidectomized patients.
The Journal of clinical endocrinology and metabolism 1993;76(5):1199-201.
1993: Koistinen R; Angervo M; Leinonen P; Seppälä M
Phosphorylation of insulin-like growth factor-binding protein-1 from different sources.
Growth regulation 1993;3(1):34-7.
1993: Insler V; Shoham Z; Barash A; Koistinen R; Seppälä M; Hen M; Lunenfeld B; Zadik Z
Polycystic ovaries in non-obese and obese patients: possible pathophysiological mechanism based on new interpretation of facts and findings.
Human reproduction (Oxford, England) 1993;8(3):379-84.
1993: Swahn M L; Bygdeman M; Seppälä M; Johannisson E; Cekan S
Effect of tamoxifen alone and in combination with RU 486 on the endometrium in the mid-luteal phase.
Human reproduction (Oxford, England) 1993;8(2):193-200.
1993: Kämäräinen M; Leivo I; Julkunen M; Seppälä M
Localization of progesterone-associated endometrial protein mRNA by in-situ hybridization in human pregnancy decidua, endometriosis and borderline endometrioid adenoma.
Journal of molecular endocrinology 1993;10(1):71-7.
1993: Angervo M; Leinonen P; Koistinen R; Julkunen M; Seppälä M
Tri-iodothyronine and cycloheximide enhance insulin-like growth factor-binding protein-1 gene expression in human hepatoma cells.
Journal of molecular endocrinology 1993;10(1):7-13.
1993: Adashi E Y; Resnick C E; Rosenfeld R G; Powell D R; Koistinen R; Rutanen E M; Seppala M
Insulin-like growth factor (IGF) binding protein-1 is an antigonadotropin: evidence that optimal follicle-stimulating hormone action in ovarian granulosa cells is contingent upon amplification by endogenously-derived IGFs.
Advances in experimental medicine and biology 1993;343():377-85.
1992: Mason H D; Willis D; Holly J M; Cwyfan-Hughes S C; Seppala M; Franks S
Inhibitory effects of insulin-like growth factor-binding proteins on steroidogenesis by human granulosa cells in culture.
Molecular and cellular endocrinology 1992;89(1-2):R1-4.
1992: Laron Z; Suikkari A M; Klinger B; Silbergeld A; Pertzelan A; Seppälä M; Koivisto V A
Growth hormone and insulin-like growth factor regulate insulin-like growth factor-binding protein-1 in Laron type dwarfism, growth hormone deficiency and constitutional short stature.
Acta endocrinologica 1992;127(4):351-8.
1992: Rutanen E M; Seppälä M
Insulin-like growth factor binding protein-1 in female reproductive functions.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 1992;39(1):3-9.
1992: Suikkari A M; Leivo I; Kämäräinen M; Holthöfer H; Seppälä M; Julkunen M; Koistinen R
Expression of insulin-like growth factor binding protein-1 mRNA in human fetal kidney.
Kidney international 1992;42(3):749-54.
1992: Reed M J; Christodoulides A; Koistinen R; Seppälä M; Teale J D; Ghilchik M W
The effect of endocrine therapy with medroxyprogesterone acetate, 4-hydroxyandrostenedione or tamoxifen on plasma concentrations of insulin-like growth factor (IGF)-I, IGF-II and IGFBP-1 in women with advanced breast cancer.
International journal of cancer. Journal international du cancer 1992;52(2):208-12.
1992: Martikainen H; Koistinen R; Seppälä M
The effect of estrogen level on glucose-induced changes in serum insulin-like growth factor binding protein-1 concentration.
Fertility and sterility 1992;58(3):543-6.
1992: Dor J; Costritsci N; Pariente C; Rabinovici J; Mashiach S; Lunenfeld B; Kaneti H; Seppälä M; Koistinen R; Karasik A
Insulin-like growth factor-I and follicle-stimulating hormone suppress insulin-like growth factor binding protein-1 secretion by human granulosa-luteal cells.
The Journal of clinical endocrinology and metabolism 1992;75(3):969-71.
1992: Angervo M; Koistinen R; Seppälä M
Epidermal growth factor stimulates production of insulin-like growth factor-binding protein-1 in human granulosa-luteal cells.
The Journal of endocrinology 1992;134(1):127-31.
1992: Seppälä M; Julkunen M; Riittinen L; Koistinen R
Endometrial proteins: a reappraisal.
Human reproduction (Oxford, England) 1992;7 Suppl 1():31-8.
1992: Dor J; Ben-Shlomo I; Lunenfeld B; Pariente C; Levran D; Karasik A; Seppälä M; Mashiach S
Insulin-like growth factor-I (IGF-I) may not be essential for ovarian follicular development: evidence from IGF-I deficiency.
The Journal of clinical endocrinology and metabolism 1992;74(3):539-42.
1992: Koninckx P R; Riittinen L; Seppala M; Cornillie F J
CA-125 and placental protein 14 concentrations in plasma and peritoneal fluid of women with deeply infiltrating pelvic endometriosis.
Fertility and sterility 1992;57(3):523-30.
1992: Nylund L; Gustafson O; Lindblom B; Pousette A; Seppälä M; Riittinen L; Akerlöf E
Placental protein 14 in human in-vitro fertilization early pregnancies.
Human reproduction (Oxford, England) 1992;7(1):128-30.
1991: Okamoto N; Uchida A; Takakura K; Kariya Y; Kanzaki H; Riittinen L; Koistinen R; Seppälä M; Mori T
Suppression by human placental protein 14 of natural killer cell activity.
American journal of reproductive immunology (New York, N.Y. : 1989) 1991;26(4):137-42.
1991: Cornillie F J; Lauweryns J M; Seppälä M; Riittinen L; Koninckx P R
Expression of endometrial protein PP14 in pelvic and ovarian endometriotic implants.
Human reproduction (Oxford, England) 1991;6(10):1411-5.
1991: Martikainen H; Tapanainen J; Rönnberg L; Kauppila A; Selenius P; Seppälä M
Insulin-like growth factor binding protein-1 and ovarian stimulation.
Human reproduction (Oxford, England) 1991;6(9):1220-2.
1991: Kämäräinen M; Julkunen M; Seppälä M
HinfI polymorphism in the human progesterone associated endometrial protein (PAEP) gene.
Nucleic acids research 1991;19(18):5092.
1991: Angervo M; Koistinen R; Suikkari A M; Seppälä M
Insulin-like growth factor binding protein-1 inhibits the DNA amplification induced by insulin-like growth factor I in human granulosa-luteal cells.
Human reproduction (Oxford, England) 1991;6(6):770-3.
1991: Tapanainen J; Rönnberg L; Martikainen H; Reinilä M; Koistinen R; Seppälä M
Short and long term effects of growth hormone on circulating levels of insulin-like growth factor-I (IGF-I), IGF-binding protein-1, and insulin: a placebo-controlled study.
The Journal of clinical endocrinology and metabolism 1991;73(1):71-4.
1991: Ruutiainen K; Seppälä M
Polycystic ovary syndrome: evolution of a concept.
Current opinion in obstetrics & gynecology 1991;3(3):326-35.
1991: Suikkari A M; Tiitinen A; Stenman U H; Seppälä M; Laatikainen T
Oral contraceptives increase insulin-like growth factor binding protein-1 concentration in women with polycystic ovarian disease.
Fertility and sterility 1991;55(5):895-9.
1991: Seppälä M; Angervo M; Koistinen R; Riittinen L; Julkunen M
Human endometrial protein secretion relative to implantation.
Baillière's clinical obstetrics and gynaecology 1991;5(1):61-72.
1991: Riittinen L; Närvänen O; Virtanen I; Seppälä M
Monoclonal antibodies against endometrial protein PP14 and their use for purification and radioimmunoassay of PP14.
Journal of immunological methods 1991;136(1):85-90.
1991: Lunenfeld B; Pariente C; Dor J; Menashe Y; Seppälä M; Mortman H; Insler V
Modern aspects of ovulation induction.
Annals of the New York Academy of Sciences 1991;626():207-16.
1991: Franks S; Kiddy D; Sharp P; Singh A; Reed M; Seppälä M; Koistinen R; Hamilton-Fairley D
Obesity and polycystic ovary syndrome.
Annals of the New York Academy of Sciences 1991;626():201-6.
1991: Seppälä M; Yajima M; Koistinen R; Angervo M; Riittinen L; Suikkari A M; Selenius P; Julkunen M
Endometrial proteins as local regulators of human endometrial function and their appearance in serum: clinical applications.
Annals of the New York Academy of Sciences 1991;626():312-20.
1991: Julkunen M; Seppälä M; Jänne O A
Molecular cloning of complementary DNAs for two human endometrial proteins and cellular localization of their messenger RNAs.
Annals of the New York Academy of Sciences 1991;626():284-94.
1991: Suikkari A M; Angervo M; Koistinen R; Jalkanen J; Seppälä M
Insulin-like growth factor-binding protein-1 (IGFBP-1) in the human ovary.
Annals of the New York Academy of Sciences 1991;626():184-8.
1990: Koistinen R; Itkonen O; Selenius P; Seppälä M
Insulin-like growth factor-binding protein-1 inhibits binding of IGF-I on fetal skin fibroblasts but stimulates their DNA synthesis.
Biochemical and biophysical research communications 1990;173(1):408-15.
1990: Laatikainen T; Anttila L; Suikkari A M; Ruutiainen K; Erkkola R; Seppälä M
Effect of naloxone on plasma insulin, insulin-like growth factor I, and its binding protein 1 in patients with polycystic ovarian disease.
Fertility and sterility 1990;54(3):434-7.
1990: Seppälä M; Suikkari A M; Koistinen R; Riittinen L; Julkunen M
Endometrial protein secretion with respect to endometrial and ovarian function.
European journal of obstetrics, gynecology, and reproductive biology 1990;36(3):250-7.
1990: Julkunen M; Koistinen R; Suikkari A M; Seppälä M; Jänne O A
Identification by hybridization histochemistry of human endometrial cells expressing mRNAs encoding a uterine beta-lactoglobulin homologue and insulin-like growth factor-binding protein-1.
Molecular endocrinology (Baltimore, Md.) 1990;4(5):700-7.
1990: Koistinen R; Suikkari A M; Tiitinen A; Kontula K; Seppälä M
Human granulosa cells contain insulin-like growth factor-binding protein (IGF BP-1) mRNA.
Clinical endocrinology 1990;32(5):635-40.
1990: Brock D J; Barron L; Holloway S; Liston W A; Hillier S G; Seppala M
First-trimester maternal serum biochemical indicators in Down syndrome.
Prenatal diagnosis 1990;10(4):245-51.
1990: Lehtovirta P; Kairemo K J; Liewendahl K; Seppälä M
Immunolymphoscintigraphy and immunoscintigraphy of ovarian and fallopian tube cancer using F(ab')2 fragments of monoclonal antibody OC 125.
Cancer research 1990;50(3 Suppl):937s-940s.
1990: Singh A; Hamilton-Fairley D; Koistinen R; Seppälä M; James V H; Franks S; Reed M J
Effect of insulin-like growth factor-type I (IGF-I) and insulin on the secretion of sex hormone binding globulin and IGF-I binding protein (IBP-I) by human hepatoma cells.
The Journal of endocrinology 1990;124(2):R1-3.
1989: Kiddy D S; Hamilton-Fairley D; Seppälä M; Koistinen R; James V H; Reed M J; Franks S
Diet-induced changes in sex hormone binding globulin and free testosterone in women with normal or polycystic ovaries: correlation with serum insulin and insulin-like growth factor-I.
Clinical endocrinology 1989;31(6):757-63.
1989: Jalkanen J; Suikkari A M; Koistinen R; Bützow R; Ritvos O; Seppälä M; Ranta T
Regulation of insulin-like growth factor-binding protein-1 production in human granulosa-luteal cells.
The Journal of clinical endocrinology and metabolism 1989;69(6):1174-9.
1989: Alitalo T; Kontula K; Koistinen R; Aalto-Setälä K; Julkunen M; Jänne O A; Seppälä M; de la Chapelle A
The gene encoding human low-molecular weight insulin-like growth-factor binding protein (IGF-BP25): regional localization to 7p12-p13 and description of a DNA polymorphism.
Human genetics 1989;83(4):335-8.
1989: Telimaa S; Kauppila A; Rönnberg L; Suikkari A M; Seppälä M
Elevated serum levels of endometrial secretory protein PP14 in patients with advanced endometriosis. Suppression by treatment with danazol and high-dose medroxyprogesterone acetate.
American journal of obstetrics and gynecology 1989;161(4):866-71.
1989: Riittinen L; Julkunen M; Seppälä M; Koistinen R; Huhtala M L
Purification and characterization of endometrial protein PP14 from mid-trimester amniotic fluid.
Clinica chimica acta; international journal of clinical chemistry 1989;184(1):19-29.
1989: Riittinen L; Stenman U H; Alfthan H; Suikkari A M; Bohn H; Seppälä M
Time-resolved immunofluorometric assay for placental protein 14.
Clinica chimica acta; international journal of clinical chemistry 1989;183(2):115-23.
1989: Seppälä M; Martikainen H; Rönnberg L; Riittinen L; Kauppila A
Suppression of prolactin secretion during ovarian hyperstimulation is followed by elevated serum levels of endometrial protein PP14 in the late luteal phase.
Human reproduction (Oxford, England) 1989;4(4):389-91.
1989: Suikkari A M; Jalkanen J; Koistinen R; Bützow R; Ritvos O; Ranta T; Seppälä M
Human granulosa cells synthesize low molecular weight insulin-like growth factor-binding protein.
Endocrinology 1989;124(2):1088-90.
1989: Suikkari A M; Ruutiainen K; Erkkola R; Seppälä M
Low levels of low molecular weight insulin-like growth factor-binding protein in patients with polycystic ovarian disease.
Human reproduction (Oxford, England) 1989;4(2):136-9.
1989: Suikkari A M; Sane T; Seppälä M; Yki-Järvinen H; Karonen S L; Koivisto V A
Prolonged exercise increases serum insulin-like growth factor-binding protein concentrations.
The Journal of clinical endocrinology and metabolism 1989;68(1):141-4.
1989: Suikkari A M; Koivisto V A; Koistinen R; Seppälä M; Yki-Järvinen H
Dose-response characteristics for suppression of low molecular weight plasma insulin-like growth factor-binding protein by insulin.
The Journal of clinical endocrinology and metabolism 1989;68(1):135-40.
1988: Julkunen M; Seppälä M; Jänne O A
Complete amino acid sequence of human placental protein 14: a progesterone-regulated uterine protein homologous to beta-lactoglobulins.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):8845-9.
1988: Bützow R; Lehto V P; Ritvos O; Ranta T; Seppälä M
Regulation of the production of placental protein 5 by human endometrial stromal cells; the role of prostaglandins E2 and F2 alpha.
Molecular and cellular endocrinology 1988;60(2-3):137-43.
1988: Bützow R; Alfthan H; Stenman U H; Suikkari A M; Bohn H; Seppälä M
Immunofluorometric demonstration and quantification of placental protein 5 in the absence of pregnancy.
Clinical chemistry 1988;34(8):1591-3.
1988: Julkunen M; Koistinen R; Aalto-Setälä K; Seppälä M; Jänne O A; Kontula K
Primary structure of human insulin-like growth factor-binding protein/placental protein 12 and tissue-specific expression of its mRNA.
FEBS letters 1988;236(2):295-302.
1988: Bützow R; Virtanen I; Seppälä M; Närvänen O; Stenman U H; Ristimäki A; Bohn H
Monoclonal antibodies reacting with placental protein 5: use in radioimmunoassay, Western blot analysis, and immunohistochemistry.
The Journal of laboratory and clinical medicine 1988;111(2):249-56.
1988: Suikkari A M; Koivisto V A; Rutanen E M; Yki-Järvinen H; Karonen S L; Seppälä M
Insulin regulates the serum levels of low molecular weight insulin-like growth factor-binding protein.
The Journal of clinical endocrinology and metabolism 1988;66(2):266-72.
1988: Bützow R; Huhtala M L; Bohn H; Virtanen I; Seppälä M
Purification and characterization of placental protein 5.
Biochemical and biophysical research communications 1988;150(1):483-90.
1988: Seppälä M; Julkunen M; Koskimies A; Laatikainen T; Stenman U H; Huhtala M L
Proteins of the human endometrium. Basic and clinical studies toward a blood test for endometrial function.
Annals of the New York Academy of Sciences 1988;541():432-44.
1988: Halila H; Lehtovirta P; Stenman U H; Seppälä M
CA 125 in the follow-up of patients with ovarian cancer.
Acta obstetricia et gynecologica Scandinavica 1988;67(1):53-8.
1988: Briese V; Than G; Richter D; Iino K; Seppälä M
[Placental protein 5 and pregnancy zone protein in ovarian cysts and benign cystic ovarian tumors]
Zentralblatt für Gynäkologie 1988;110(13):821-3.
1988: Seppälä M; Riittinen L; Julkunen M; Koistinen R; Wahlström T; Iino K; Alfthan H; Stenman U H; Huhtala M L
Structural studies, localization in tissue and clinical aspects of human endometrial proteins.
Journal of reproduction and fertility. Supplement 1988;36():127-41.
1988: Koskimies A L; Seppälä M
[Life beneath the microscope]
Duodecim; lääketieteellinen aikakauskirja 1988;104(17):1305-9.
1988: Seppälä M; Suikkari A M; Julkunen M
Human endometrial proteins.
Reproduction, nutrition, development 1988;28(6B):1649-54.
1987: Seppälä M; Alfthan H; Vartiainen E; Stenman U H
The post-menopausal uterus: the effect of hormone replacement therapy on the serum levels of secretory endometrial protein PP14/beta-lactoglobulin homologue.
Human reproduction (Oxford, England) 1987;2(8):741-3.
1987: Than G; Seppälä M; Julkunen M; Szabo D; Bodis J; Szilagyi A; Csaba I
The effect of Danazol on the circulating levels of 34K insulin-like growth factor-binding protein (PP12) and endometrial secretory protein PP14.
Human reproduction (Oxford, England) 1987;2(7):549-51.
1987: Seppälä M; Rönnberg L; Karonen S L; Kauppila A
Micronized oral progesterone increases the circulating level of endometrial secretory PP14/beta-lactoglobulin homologue.
Human reproduction (Oxford, England) 1987;2(6):453-5.
1987: von Koskull H; Ammälä P; Huhtala M L; Seppälä M
Localization of insulin-like growth factor-binding protein and endometrial beta-lactoglobulin in cultured decidual and chorionic villus cells.
Human reproduction (Oxford, England) 1987;2(5):431-4.
1987: Koistinen R; Stenman U H; Alfthan H; Seppälä M
Time-resolved immunofluorometric assay of 34-kDa somatomedin-binding protein.
Clinical chemistry 1987;33(7):1126-8.
1987: Huhtala M L; Seppälä M; Närvänen A; Palomäki P; Julkunen M; Bohn H
Amino acid sequence homology between human placental protein 14 and beta-lactoglobulins from various species.
Endocrinology 1987;120(6):2620-2.
1987: Koistinen R; Huhtala M L; Stenman U H; Seppälä M
Purification of placental protein PP12 from human amniotic fluid and its comparison with PP12 from placenta by immunological, physicochemical and somatomedin-binding properties.
Clinica chimica acta; international journal of clinical chemistry 1987;164(3):293-303.
1987: Suikkari A M; Rutanen E M; Seppälä M
Circulating levels of immunoreactive insulin-like growth factor-binding protein in non-pregnant women.
Human reproduction (Oxford, England) 1987;2(4):297-300.
1987: Bützow R; Huhtaniemi I; Clayton R; Wahlström T; Andersson L C; Seppälä M
Cultured mammary carcinoma cells contain gonadotropin-releasing hormone-like immunoreactivity, GnRH binding sites and chorionic gonadotropin.
International journal of cancer. Journal international du cancer 1987;39(4):498-501.
1987: Stenman U H; Alfthan H; Ranta T; Vartiainen E; Jalkanen J; Seppälä M
Serum levels of human chorionic gonadotropin in nonpregnant women and men are modulated by gonadotropin-releasing hormone and sex steroids.
The Journal of clinical endocrinology and metabolism 1987;64(4):730-6.
1987: Halila H; Suikkari A M; Seppälä M
The effect of hysterectomy on serum CA 125 levels in patients with adenomyosis and uterine fibroids.
Human reproduction (Oxford, England) 1987;2(3):265-6.
1987: Seppälä M; Purhonen M
The use of hCG and other pregnancy proteins in the diagnosis of ectopic pregnancy.
Clinical obstetrics and gynecology 1987;30(1):148-54.
1987: Julkunen M; Seppälä M
[A novel protein related to endometrial function]
Duodecim; lääketieteellinen aikakauskirja 1987;103(6):315-20.
1987: Than G; Tiitinen A; Seppälä M; Csaba I; Bohn H
Placental protein 10: levels in benign and malignant ovarian cyst fluids and pleural exudates.
Archives of gynecology 1987;240(2):115-8.
1987: Tiitinen A; Bützow R; Koistinen R; Seppälä M
Human endometrium and menstrual fluid contain placental protein 10 (PP10).
Archives of gynecology 1987;240(2):107-13.
1987: Than G; Seppälä M; Csaba I; Iino K; Briese V
Placental protein 5 in benign and malignant ovarian cyst fluids.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1987;8(4):230-1.
1987: Rutanen E M; Koistinen R; Seppälä M; Julkunen M; Suikkari A M; Huhtala M L
Progesterone-associated proteins PP12 and PP14 in the human endometrium.
Journal of steroid biochemistry 1987;27(1-3):25-31.
1987: Stenman U H; Seppälä M
Biochemical and immunologic diagnosis of cancer. Ovarian cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1987;8(2-3):109-12.
1987: Tiitinen A; Than G N; Iino K; Halila H; Seppälä M
Placental protein 10 (PP10) in the serum of patients with trophoblastic and nontrophoblastic gynaecological tumours.
Archives of gynecology and obstetrics 1987;241(1):43-6.
1987: Seppälä M; Than G
Insulin-like growth factor-binding protein PP12 in ovarian cyst fluid.
Archives of gynecology and obstetrics 1987;241(1):33-5.
1986: Huhtala M L; Koistinen R; Palomäki P; Partanen P; Bohn H; Seppälä M
Biologically active domain in somatomedin-binding protein.
Biochemical and biophysical research communications 1986;141(1):263-70.
1986: Iino K; Seppälä M; Heinonen P K; Sipponen P; Rutanen E M
Elevated levels of a somatomedin-binding protein PP12 in patients with ovarian cancer.
Cancer 1986;58(10):2294-7.
1986: Seppälä M; Iino K; Rutanen E M
Placental proteins in oncology.
Clinics in obstetrics and gynaecology 1986;13(3):593-610.
1986: Tiitinen A; Wahlström T; Julkunen M; Seppälä M
The content and immunohistochemical localization of placental protein 10 (PP10) in the fallopian tube.
British journal of obstetrics and gynaecology 1986;93(9):924-7.
1986: Bützow R; Alfthan H; Julkunen M; Rutanen E M; Bohn H; Seppälä M
Human endometrium and menstrual fluid contain placental protein 5 (PP5).
Human reproduction (Oxford, England) 1986;1(5):287-9.
1986: Iino K; Sjöberg J; Seppälä M
Elevated circulating levels of a decidual protein, placental protein 12, in preeclampsia.
Obstetrics and gynecology 1986;68(1):58-60.
1986: Julkunen M; Wahlström T; Seppälä M
Human fallopian tube contains placental protein 14.
American journal of obstetrics and gynecology 1986;154(5):1076-9.
1986: Julkunen M; Koistinen R; Sjöberg J; Rutanen E M; Wahlström T; Seppälä M
Secretory endometrium synthesizes placental protein 14.
Endocrinology 1986;118(5):1782-6.
1986: Halila H; Stenman U H; Seppälä M
Ovarian cancer antigen CA 125 levels in pelvic inflammatory disease and pregnancy.
Cancer 1986;57(7):1327-9.
1986: Koistinen R; Kalkkinen N; Huhtala M L; Seppälä M; Bohn H; Rutanen E M
Placental protein 12 is a decidual protein that binds somatomedin and has an identical N-terminal amino acid sequence with somatomedin-binding protein from human amniotic fluid.
Endocrinology 1986;118(4):1375-8.
1986: Rutanen E M; Koistinen R; Sjöberg J; Julkunen M; Wahlström T; Bohn H; Seppälä M
Synthesis of placental protein 12 by human endometrium.
Endocrinology 1986;118(3):1067-71.
1986: Julkunen M; Apter D; Seppälä M; Stenman U H; Bohn H
Serum levels of placental protein 14 reflect ovulation in nonconceptional menstrual cycles.
Fertility and sterility 1986;45(1):47-50.
1986: Julkunen M; Raikar R S; Joshi S G; Bohn H; Seppälä M
Placental protein 14 and progestagen-dependent endometrial protein are immunologically indistinguishable.
Human reproduction (Oxford, England) 1986;1(1):7-8.
1986: Iino K; Julkunen M; Sjöberg J; Seppälä M
Is decidua affected in gestational hypertension? Indication by elevated PP14 levels.
Acta obstetricia et gynecologica Scandinavica 1986;65(4):367-70.
1985: Julkunen M; Rutanen E M; Koskimies A; Ranta T; Bohn H; Seppälä M
Distribution of placental protein 14 in tissues and body fluids during pregnancy.
British journal of obstetrics and gynaecology 1985;92(11):1145-51.
1985: Tiitinen A; Laatikainen T; Rutanen E M; Ranta T; Koistinen R; Bohn H; Seppälä M
Placental protein 10 (PP10) in normal pregnancy and cholestasis of pregnancy.
British journal of obstetrics and gynaecology 1985;92(11):1137-40.
1985: Rutanen E M; Koistinen R; Wahlström T; Bohn H; Ranta T; Seppälä M
Synthesis of placental protein 12 by human decidua.
Endocrinology 1985;116(4):1304-9.
1985: Seppälä M; Koskimies A I
[In vitro fertilization]
Duodecim; lääketieteellinen aikakauskirja 1985;101(15):1464-74.
1985: Seppälä M
The world collaborative report on in vitro fertilization and embryo replacement: current state of the art in January 1984.
Annals of the New York Academy of Sciences 1985;442():558-63.
1985: Yki-Järvinen H; Wahlström T; Seppälä M
Human endometrium contains relaxin that is progesterone-dependent.
Acta obstetricia et gynecologica Scandinavica 1985;64(8):663-5.
1985: Stenman U H; Alfthan H; Seppälä M
New methods revolutionize assays of polypeptide hormones and proteins.
Acta obstetricia et gynecologica Scandinavica 1985;64(8):627-8.
1985: Seppälä M; Koskimies A I; Tenhunen A; Rutanen E M; Sjöberg J; Koistinen R; Julkunen M; Wahlström T
Pregnancy proteins in seminal plasma, seminal vesicles, preovulatory follicular fluid, and ovary.
Annals of the New York Academy of Sciences 1985;442():212-26.
1985: Edwards R G; Seppälä M; Johnston W I; Jones H W; Rauramo L; Semm K; Widholm O; Wiqvist N
Helsinki statement on human in vitro fertilization.
Annals of the New York Academy of Sciences 1985;442():571-2.
1985: Stenman U H; Alfthan H; Koskimies A; Seppälä M; Pettersson K; Lövgren T
Monitoring the LH surge by ultrarapid and highly sensitive immunofluorometric assay.
Annals of the New York Academy of Sciences 1985;442():544-50.
1985: Wahlström T; Koskimies A I; Tenhunen A; Rutanen E M; Yki-Järvinen H; Julkunen M; Sjöberg J; Seppälä M
Pregnancy proteins in the endometrium after follicle aspiration for in vitro fertilization.
Annals of the New York Academy of Sciences 1985;442():402-7.
1985: Seppälä M; Rutanen E M
[Fetal and placental proteins]
Duodecim; lääketieteellinen aikakauskirja 1985;101(3):323-33.
1985: Sinosich M J; Dodd J; Hudson C N; Tyler J R; Seppala M; Grudzinskas J G; Saunders D M
The influence of pergonal on in vitro production of placental protein 5 (PP5) by ovarian tumour cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1985;6(3):233-42.
1985: Sjöberg J; Wahlström T; Seppälä M; Rutanen E M; Koistinen R; Koskimies A I; Sinosich M J; Teisner B; Grudzinskas J G
Seminal plasma levels of PAPP-A in normospermic and oligospermic men and tissue localization of PAPP-A in the male genital tract.
Archives of andrology 1985;14(2-3):253-61.
1985: Sinosich M J; Seppälä M; Saunders D M; Grudzinskas J G
Pregnancy-associated plasma protein-A and placental protein 5 in human seminal plasma.
Annals of the New York Academy of Sciences 1985;442():287-92.
1984: Rutanen E M; Koistinen R; Wahlström T; Bohn H; Seppälä M
The content of placental protein 12 in decidua and fetal membranes is greater than in placenta.
British journal of obstetrics and gynaecology 1984;91(12):1240-4.
1984: Rutanen E M; Koistinen R; Wahlström T; Stenman U H; Seppälä M
Placental protein 12 (PP12) in menstrual fluid.
British journal of obstetrics and gynaecology 1984;91(10):1025-30.
1984: Yki-Järvinen H; Wahlström T; Tenhunen A; Koskimies A I; Seppälä M
The occurrence of relaxin in hyperstimulated human preovulatory follicles collected in an in vitro fertilization program.
Journal of in vitro fertilization and embryo transfer : IVF 1984;1(3):180-2.
1984: Koskimies A I; Tenhunen A; Ylöstalo P; Liukkonen S; Widholm O; Seppälä M
The in vitro fertilization program in Helsinki.
Journal of in vitro fertilization and embryo transfer : IVF 1984;1(3):208-9.
1984: Salem H T; Menabawey M; Seppälä M; Shaaban M M; Chard T
Human seminal plasma contains a wide range of trophoblast-'specific' proteins.
Placenta 1984;5(5):413-7.
1984: Rutanen E M; Seppälä M; Pietilä R; Bohn H
Placental protein 12 (PP12): factors affecting levels in late pregnancy.
Placenta 1984;5(3):243-8.
1984: Wahlström T; Seppälä M
Placental protein 12 (PP12) is induced in the endometrium by progesterone.
Fertility and sterility 1984;41(5):781-4.
1984: Rutanen E M; Koistinen R; Wahlström T; Sjöberg J; Stenman U H; Seppälä M
Placental protein 12 (PP12) in the human endometrium: tissue concentration in relation to histology and serum levels of PP12, progesterone and oestradiol.
British journal of obstetrics and gynaecology 1984;91(4):377-81.
1984: Ylöstalo P; Ammälä P; Seppälä M
Intrauterine haematoma and placental protein 5 in patients with uterine bleeding during pregnancy.
British journal of obstetrics and gynaecology 1984;91(4):353-6.
1984: Cooper R L; Seppala M; Linnoila M
Effect of luteinizing hormone-releasing hormone antiserum on sexual behavior in the female rat.
Pharmacology, biochemistry, and behavior 1984;20(4):527-30.
1984: Seppälä M; Wahlström T; Koskimies A I; Tenhunen A; Rutanen E M; Koistinen R; Huhtaniemi I; Bohn H; Stenman U H
Human preovulatory follicular fluid, luteinized cells of hyperstimulated preovulatory follicles, and corpus luteum contain placental protein 12.
The Journal of clinical endocrinology and metabolism 1984;58(3):505-10.
1984: Sjöberg J; Wahlström T; Seppälä M
Pregnancy-associated plasma protein A in the human endometrium is dependent on the effect of progesterone.
The Journal of clinical endocrinology and metabolism 1984;58(2):359-62.
1984: Seppälä M; Tenhunen A; Koskimies A I; Wahlström T; Koistinen R; Stenman U H
Hyperstimulated human preovulatory follicular fluid contains placental protein 5 (PP5).
Fertility and sterility 1984;41(1):62-5.
1984: Julkunen M; Wahlström T; Seppälä M; Koistinen R; Koskimies A; Stenman U H; Bohn H
Detection and localization of placental protein 14-like protein in human seminal plasma and in the male genital tract.
Archives of andrology 1984;12 Suppl():59-67.
1984: Boltenberg A; Furgyik S; Kullander S; Rausing A; Seppälä M; Wahlström T
Growth and function of human placenta and amnion grafted to nude mice. A preliminary communication.
Acta obstetricia et gynecologica Scandinavica 1984;63(7):621-4.
1984: Rutanen E M; Wahlström T; Koistinen R; Sipponen P; Jalanko H; Seppälä M
Placental protein 12 (PP12) in primary liver cancer and cirrhosis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1984;5(2):95-102.
1983: Yki-Järvinen H; Wahlström T; Seppälä M
Immunohistochemical demonstration of relaxin in gynecologic tumors.
Cancer 1983;52(11):2077-80.
1983: Yki-Järvinen H; Wahlström T; Seppälä M
Immunohistochemical demonstration of relaxin in the genital tract of men.
Journal of reproduction and fertility 1983;69(2):693-5.
1983: Wahlström T; Huhtaniemi I; Hovatta O; Seppälä M
Localization of luteinizing hormone, follicle-stimulating hormone, prolactin, and their receptors in human and rat testis using immunohistochemistry and radioreceptor assay.
The Journal of clinical endocrinology and metabolism 1983;57(4):825-30.
1983: Yki-Järvinen H; Wahlström T; Seppälä M
Immunohistochemical demonstration of relaxin in the genital tract of pregnant and nonpregnant women.
The Journal of clinical endocrinology and metabolism 1983;57(3):451-4.
1983: Stenman U H; Alfthan H; Myllynen L; Seppälä M
Ultrarapid and highly sensitive time-resolved fluoroimmunometric assay for chorionic gonadotropin.
Lancet 1983;2(8351):647-9.
1983: Heikinheimo M; Seppälä M
Amniotic fluid human chorionic gonadotropin in late pregnancy: elevated levels in toxemia with intrauterine growth retardation.
American journal of obstetrics and gynecology 1983;146(7):766-8.
1983: Salem H T; Shaaban M M; Ghaneimah S A; Seppälä M; Chard T
Circulating levels of placental proteins, placental protein 5 (PP5), placental lactogen and Schwangerschafts-protein 1 (SP1), in antepartum eclampsia.
British journal of obstetrics and gynaecology 1983;90(7):618-22.
1983: Huhtala M L; Kahanpää K; Seppälä M; Halila H; Stenman U H
Excretion of a tumor-associated trypsin inhibitor (TATI) in urine of patients with gynecological malignancy.
International journal of cancer. Journal international du cancer 1983;31(6):711-4.
1983: Ryynänen M; Seppälä M; Kuusela P; Rapola J; Aula P; Seppä A; Jokela V; Castren O
Antenatal screening for congenital nephrosis in Finland by maternal serum alpha-fetoprotein.
British journal of obstetrics and gynaecology 1983;90(5):437-42.
1983: Seppälä M; Rutanen E M; Siiteri J E; Wahlström T; Koistinen R; Pietilä R; Bohn H
Immunologic and biological properties and clinical significance of placental proteins PP5 and PP12.
Annals of the New York Academy of Sciences 1983;417():368-82.
1982: Wahlström T; Bohn H; Seppälä M
Immunohistochemical demonstration of placental protein 5 (PP5) -like material in the seminal vesicle and the ampullar part of vas deferens.
Life sciences 1982;31(24):2723-5.
1982: Rutanen E M; Bohn H; Seppälä M
Radioimmunoassay of placental protein 12: levels in amniotic fluid, cord blood, and serum of healthy adults, pregnant women, and patients with trophoblastic disease.
American journal of obstetrics and gynecology 1982;144(4):460-3.
1982: Stenman U H; Huhtala M L; Koistinen R; Seppälä M
Immunochemical demonstration of an ovarian cancer-associated urinary peptide.
International journal of cancer. Journal international du cancer 1982;30(1):53-7.
1982: Siiteri J E; Koistinen R; Salem H T; Bohn H; Seppälä M
Placental protein 5 is related to blood coagulation and fibrinolytic systems.
Life sciences 1982;30(22):1885-91.
1982: Heikinheimo M; Aula P; Rapola J; Wahlström T; Jalanko H; Seppälä M
Amniotic fluid pregnancy-specific beta 1-glycoprotein (SP1) in Meckel's syndrome: a new test for prenatal diagnosis?
Prenatal diagnosis 1982;2(2):103-8.
1982: Stenman U H; Tanner P; Ranta T; Schröder J; Seppälä M
Monoclonal antibodies to chorionic gonadotropin: use in a rapid radioimmunoassay for gynecologic emergencies.
Obstetrics and gynecology 1982;59(3):375-7.
1982: Seppälä M; Rutanen E M; Stenman U H; Siiteri J E
Pregnancy-specific beta 1-glycoprotein in complicated early pregnancy and trophoblastic disease.
La Ricerca in clinica e in laboratorio 1982;12(1):251-4.
1982: Lee J N; Wahlström T; Seppälä M; Salem H T; Ouyang P C; Chard T
Immunohistochemical demonstration of placental protein 5 in trophoblastic tumours.
Placenta 1982;3(1):67-70.
1982: Siiteri J E; Koistinen R; Bohn H; Seppälä M
Placental protein 5 (PP5)-like immunoreactivity in human urine.
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine 1982;3(5-6):403-7.
1982: Ylikorkala O; Seppälä M
[The role of the fetus in labor]
Duodecim; lääketieteellinen aikakauskirja 1982;98(9):674-81.
1981: Ranta T; Siiteri J E; Koistinen R; Salem H T; Bohn H; Koskimies A I; Seppälä M
Human seminal plasma contains a protein that shares physicochemical and immunochemical properties with placental protein 5 from the human placenta.
The Journal of clinical endocrinology and metabolism 1981;53(5):1087-9.
1981: Salem H T; Seppälä M; Chard T
The effect of thrombin on serum placental protein 5 (PP5): is PP5 the naturally occurring antithrombin III of the human placenta?
Placenta 1981;2(3):205-9.
1981: Seppälä M
[Technology and humaneness in obstetric and gynecologic care]
Kätilölehti 1981;86(7-8):225-6.
1981: Wahlström T; Stenman U H; Lundqvist C; Tanner P; Schröder J; Seppälä M
The use of monoclonal antibodies against human chorionic gonadotropin for immunoperoxidase staining of normal placenta, pituitary gland, and pituitary adenomas.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1981;29(7):864-5.
1981: Wahlström T; Seppälä M
Immunological evidence for the occurrence of luteinizing hormone-releasing factor and the alpha-subunit of glycoprotein hormones in carcinoid tumors.
The Journal of clinical endocrinology and metabolism 1981;53(1):209-12.
1981: Lee J N; Wahlström T; Ouyang P C; Chen T Y; Seppälä M
Immunohistochemical evidence for prolactin in trophoblastic tumors.
Gynecologic oncology 1981;11(3):299-303.
1981: Karjalainen O; Aula P; Seppälä M; Hartikainen-Sorri A L; Ryynänen M
Prenatal diagnosis of the Meckel syndrome.
Obstetrics and gynecology 1981;57(6 Suppl):13S-5S.
1981: Saksela O; Wahlström T; Lehtovirta P; Seppälä M; Vaheri A
Presence of alpha 2-macroglobulin in normal but not in malignant human syncytiotrophoblasts.
Cancer research 1981;41(6):2507-13.
1981: Salem H T; Westergaard J G; Hindersson P; Seppälä M; Chard T
Placental protein 5 (PP5) in placental abruption.
British journal of obstetrics and gynaecology 1981;88(5):500-3.
1981: Ranta T; Wahlström T; Rutanen E M; Stenman U H; Seppälä M
Serum prolactin levels and immunohistochemical localization of prolactin in trophoblastic disease.
Acta pathologica et microbiologica Scandinavica. Section A, Pathology 1981;89(3):235-9.
1981: Salem H T; Seppälä M; Ranta T; Bohn H; Chard T
The effect of protamine on serum levels of placental protein 5 (PP5) in normal and abnormal pregnancy: a possible relation to coagulation abnormalities.
British journal of obstetrics and gynaecology 1981;88(4):367-70.
1981: Heikinheimo M; Saksela O; Lehtovirta P; Seppälä M; Bohn H
Cultured human syncytiotrophoblasts synthesize pregnancy-specific beta-1-glycoprotein (SP1).
Acta pathologica et microbiologica Scandinavica. Section C, Immunology 1981;89(2):139-44.
1981: Salem H T; Lee J N; Seppälä M; Vaara L; Aula P; Al-Ani A T; Chard T
Measurement of placental protein 5, placental lactogen and pregnancy-specific beta 1 glycoprotein in mid-trimester as a predictor of outcome of pregnancy.
British journal of obstetrics and gynaecology 1981;88(4):371-4.
1981: Lehtovirta P; Ranta T; Seppälä M
Elevated prolactin levels in oral contraceptive pill-related hypertension.
Fertility and sterility 1981;35(4):403-5.
1981: Siiteri J E; Koistinen R; Ranta T; Stenman U H; Seppälä M
Use of a rapid radioimmunoassay for pregnancy-specific beta-1 glycoprotein in gynecologic emergencies: comparison with routine urinary pregnancy test and a rapid radioimmunoassay for human chorionic gonadotropin.
American journal of obstetrics and gynecology 1981;139(8):968-70.
1981: Ranta T; Rutanen E M; Seppälä M; Stenman U H; Tontti K
[Early pregnancy diagnosis with rapid, specific radioimmunological determination of hCG in serum]
Läkartidningen 1981;78(13):1307-8.
1981: Lee J N; Seppälä M; Chard T
Characterization of placental luteinizing hormone-releasing factor-like material.
Acta endocrinologica 1981;96(3):394-7.
1981: Lee J N; Salem H T; Al-Ani A T; Chard T; Huang S C; Ouyang P C; Wei P Y; Seppälä M
Circulating concentrations of specific placental proteins (human chorionic gonadotropin, pregnancy-specific beta-1 glycoprotein, and placental protein 5) in untreated gestational trophoblastic tumors.
American journal of obstetrics and gynecology 1981;139(6):702-4.
1981: Lee J N; Salem H T; Huang S c; Ouyang P C; Seppälä M; Chard T
Placental protein 5 (PP5) in severe pre-eclampsia and eclampsia.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 1981;19(1):65-7.
1981: Seppälä M; Ranta T; Rutanen E M; Stenman U H; Tontti K; Chard T
Improved diagnosis of pregnancy-related gynaecological emergencies by rapid human chorionic gonadotrophin beta-subunit assay.
British journal of obstetrics and gynaecology 1981;88(2):138-40.
1981: Ranta T; Rutanen E M; Stenman U H; Weitzel H; Seppälä M
[Improved diagnosis of pregnancy-associated gynaecological emergencies via rapid beta-HCG test (author's transl)]
Geburtshilfe und Frauenheilkunde 1981;41(2):91-2.
1981: Wahlström T; Teisner B; Lee J N; Grudzinskas J G; Seppälä M; Folkersen J
Placenta-associated plasma protein-A (PAPP-A, SP4) in trophoblastic tumours.
Acta pathologica et microbiologica Scandinavica. Section A, Pathology 1981;89(1):65-6.
1981: Koistinen R; Heikinheimo M; Rutanen E M; Stenman U H; Lee J N; Seppälä M
Concanavalin A binding of pregnancy-specific beta-1-glycoprotein in normal pregnancy and trophoblastic disease.
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine 1981;2(3):179-82.
1981: Seppälä M
[Oncofetal proteins in diagnosis of fetal malformations and cancer]
Duodecim; lääketieteellinen aikakauskirja 1981;97(10):652-62.
1980: Heikinheimo M; Wahlström T; Aula P; Virtanen I; Seppälä M
Pregnancy-specific beta-1-glycoprotein (SP1) in cultured amniotic fluid cells.
The Journal of clinical endocrinology and metabolism 1980;51(6):1432-6.
1980: Kinnunen P K; Unnérus H A; Ranta T; Ehnholm C; Nikkilä E A; Seppälä M
Activities of post-heparin plasma lipoprotein lipase and hepatic lipase during pregnancy and lactation.
European journal of clinical investigation 1980;10(6):469-74.
1980: Salem H T; Obiekwe B C; Al-Ani A T; Seppälä M; Chard T
Molecular heterogeneity of placental protein 5 (PP5) in late pregnancy serum and plasma: evidence for a heparin-PP5 polymer.
Clinica chimica acta; international journal of clinical chemistry 1980;107(3):211-5.
1980: Bohm H; Grudzinskas J G; Rosen S; Seppala M; Tatarinov Y S; Chard T; Klopper A; Schultz-Larsen P; Sizaret P; Teisner B
Reference preparation for assay of some pregnancy and cancer associated proteins.
Lancet 1980;2(8198):796.
1980: Ranta T; Lehtovirta P; Stenman U H; Laatikainen T; Seppälä M
Acute changes in serum prolactin concentration have no effect on the secretion of progesterone, estradiol, or chorionic gonadotropin during early pregnancy.
The Journal of clinical endocrinology and metabolism 1980;51(3):544-7.
1980: Seppälä M; Wahlström T
Identification of luteinizing hormone-releasing factor and alpha subunit of glycoprotein hormones in ductal carcinoma of the mammary gland.
International journal of cancer. Journal international du cancer 1980;26(3):267-8.
1980: Heikinheimo M; Seppälä M; Brock D J
Pregnancy specific beta 1-glycoprotein and human chorionic gonadotrophin levels n amniotic fluid and maternal serum in the first half of pregnancy.
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine 1980;1(1):71-6.
1980: Seppälä M; Wahlström T
Identification of luteinizing hormone-releasing factor and alpha-subunit of glycoprotein hormones in human pancreatic islets.
Life sciences 1980;27(5):395-7.
1980: Kauppila A; Rantakylä P; Huhtaniemi I; Ylikorkala O; Seppälä M
Trophoblastic markers in the differential diagnosis of ectopic pregnancy.
Obstetrics and gynecology 1980;55(5):560-4.
1980: Seppälä M; Wahlström T; Lehtovirta P; Lee J N; Leppälouto J
Immunohistochemical demonstration of luteinizing hormone-releasing factor-like material in human syncytiotrophoblast and trophoblastic tumours.
Clinical endocrinology 1980;12(5):441-51.
1980: Ranta T; Stenman U H; Unnérus H A; Rossi J; Seppälä M
Maternal plasma prolactin levels in preeclampsia.
Obstetrics and gynecology 1980;55(4):428-30.
1980: Brock D J; Hayward C; Seppala M
Distinguishing neural tube defects and congenital nephrosis by amniotic fluid assay.
Lancet 1980;1(8171):773.
1980: Ylikorkala O; Siljander M; Huhtaniemi I; Kauppila A; Seppälä M
Trophoblastic markers in women using intrauterine contraception.
Obstetrics and gynecology 1980;55(3):329-32.
1980: Jouppila P; Seppälä M; Chard T
Pregnancy-specific beta-glycoprotein in complications of early pregnancy.
Lancet 1980;1(8170):667-8.
1980: Wahlström T; Seppälä M
Tissue CEA test in endocervical and endometrial adenocarcinoma.
Lancet 1980;1(8168 Pt 1):597.
1980: Seppälä M; Venesmaa P; Rutanen E M
Pregnancy-specific beta-1 glycoprotein in ectopic pregnancy.
American journal of obstetrics and gynecology 1980;136(2):189-93.
1980: Rutanen E M; Seppälä M
Pregnancy-specific beta-1-glycoprotein in trophoblastic disease.
The Journal of clinical endocrinology and metabolism 1980;50(1):57-61.
1980: Ikonen R S; Lindgren J; Niemi E; Sorto A E; Seppälä M; Ruoslahti E
Alpha fetoprotein levels in neonatal hyperbilirubinaemia.
Acta paediatrica Scandinavica 1980;69(1):59-63.
1980: Seppälä M; Tontti K; Ranta T; Stenman U H; Chard T
Use of a rapid hCG-beta-subunit radioimmunoassay in acute gynaecological emergencies.
Lancet 1980;1(8161):165-6.
1980: Seppälä M; Tontti K; Ranta T; Stenman U H
[Rapid and specific determination of serum HCG in gynecological emergencies]
Duodecim; lääketieteellinen aikakauskirja 1980;96(9):667-72.
1980: Seppälä M
[Hyperprolactinemia and pregnancy]
Duodecim; lääketieteellinen aikakauskirja 1980;96(2):163-7.
1980: Wahlström T; Lindgren J; Korhonen M; Seppälä M
[Differential diagnosis of adenocarcinoma of the uterus and cervix using CEA immunohistochemical staining]
Duodecim; lääketieteellinen aikakauskirja 1980;96(11):804-7.
1979: Lindgren J; Sipponen P; Seppälä K; Tarpila S; Nordling S; Wahlström T; Seppälä M
Carcinoembryonic antigen in endoscopic brush specimens from benign and malignant gastric lesions.
British journal of cancer 1979;40(6):848-55.
1979: Wahlström T; Seppälä M
Luteinizing hormone-releasing factor-like immunoreactivity in islet cells and insulomas of the human pancreas.
International journal of cancer. Journal international du cancer 1979;24(6):744-8.
1979: Wahlström T; Lindgren J; Korhonen M; Seppälä M
Distinction between endocervical and endometrial adenocarcinoma with immunoperoxidase staining of carcinoembryonic antigen in routine histological tissue specimens.
Lancet 1979;2(8153):1159-60.
1979: Seppälä M; Rönnberg L; Ylöstalo P; Jouppila P
Early detection of implantation by pregnancy-specific beta 1-glycoprotein secretion in an infertile woman treated by artificial insemination and human chorionic gonadotropin.
Fertility and sterility 1979;32(5):608-9.
1979: Hovatta O; Koskimies A I; Ranta T; Stenman U H; Seppälä M
Bromocriptine treatment of oligospermia: a double blind study.
Clinical endocrinology 1979;11(4):377-82.
1979: Seppälä M; Wahlström T; Leppäluoto J
Luteinizing hormone-releasing factor (LRF)-like immunoreactivity in rat pancreatic islet cells.
Life sciences 1979;25(17):1489-96.
1979: Ylikorkala O; Huhtaniemi I; Tuimala R; Seppälä M
Subnormal postconceptional levels of prolactin do not interfere with the early events of human pregnancy.
Fertility and sterility 1979;32(3):286-8.
1979: Ruoslahti E; Pekkala A; Comings D E; Seppålå M
Determination of subfractions of amniotic fluid alpha-fetoprotein in diagnosing spina bifida and congenital nephrosis.
British medical journal 1979;2(6193):768-9.
1979: Aula P; Karjalainen O; Teramo K; Vaara L; Seppälä M
Safety and accuracy of midtrimester amniocentesis for prenatal diagnosis of genetic disorders.
Annals of clinical research 1979;11(4):156-63.
1979: Juntunen J; Kaste M; Iivanainen M; Ranta T; Seppälä M
Bromocriptine treatment of spasmodic torticollis. A double-blind crossover study.
Archives of neurology 1979;36(7):449-50.
1979: Seppälä M; Wahlström T; Bohn H
Circulating levels and tissue localization of placental protein five (PP5) in pregnancy and trophoblastic disease: absence of PP5 expression in the malignant trophoblast.
International journal of cancer. Journal international du cancer 1979;24(1):6-10.
1979: Ruoslahti E; Estes T; Seppäla M
Binding of bilirubin by bovine and human alpha-fetoprotein.
Biochimica et biophysica acta 1979;578(2):511-9.
1979: Ranta T; Unnérus H A; Rossi J; Seppälä M
Elevated plasma prolactin concentration in cholestasis of pregnancy.
American journal of obstetrics and gynecology 1979;134(1):1-3.
1979: Lindgren J; Wahlström T; Seppälä M
Tissue CEA in premalignant epithelial lesions and epidermoid carcinoma of the uterine cervix: prognostic significance.
International journal of cancer. Journal international du cancer 1979;23(4):448-53.
1979: Ranta T; Lehtovirta P; Stenman U H; Seppälä M
Serum prolactin and progesterone concentrations in ovulatory infertility.
Journal of endocrinological investigation 1979;2(1):71-3.
1979: Seppälä M; Rutanen E M
[Pregnancy specific beta-1-glycoprotein]
Duodecim; lääketieteellinen aikakauskirja 1979;95(22):1490-8.
1979: Ruoslahti E; Seppälä M
alpha-Fetoprotein in cancer and fetal development.
Advances in cancer research 1979;29():275-346.
1979: Lehtovirta P; Arjomaa P; Ranta T; Laatikainen T; Hirvonen E; Seppälä M
Prolactin levels and bromocriptine treatment of short luteal phase.
International journal of fertility 1979;24(1):57-60.
1978: Seppälä M; Rutanen E M; Jalanko H; Lehtovirta P; Stenman U H; Engvall E
Pregnancy-specific beta 1-glycoprotein and chorionic gonadotropin-like immunoreactivity during the latter half of the cycle in women using intrauterine contraception.
The Journal of clinical endocrinology and metabolism 1978;47(6):1216-9.
1978: Ruoslahti E; Engvall E; Pekkala A; Seppälä M
Developmental changes in carbohydrate moiety of human alpha-fetoprotein.
International journal of cancer. Journal international du cancer 1978;22(5):515-20.
1978: Ryynänen M; Castren O; Rapola J; Aula P; Seppälä M
Prenatal screening for congenital nephrosis.
Lancet 1978;2(8097):991.
1978: Aula P; Rapola J; Karjalainen O; Lindgren J; Hartikainen A L; Seppälä M
Prenatal diagnosis of congenital nephrosis in 23 high-risk families.
American journal of diseases of children (1960) 1978;132(10):984-7.
1978: Heikinheimo M; Unnérus H A; Ranta T; Jalanko H; Seppälä M
Pregnancy-specific beta-1-glycoprotein levels in cholestasis of pregnancy.
Obstetrics and gynecology 1978;52(3):276-8.
1978: Iivanainen M; Kaste M; Juntunen J; Kruus S; Ranta T; Seppälä M
Effect of bromocriptine on dystonic-athetoid dyskinesias in mentally retarded patients.
Journal of mental deficiency research 1978;22(3):193-6.
1978: Mandelin M; Rutanen E M; Heikinheimo M; Jalanko H; Seppälä M
Pregnancy-specific beta-1-glycoprotein and chorionic gonadotropin levels after first-trimester abortions.
Obstetrics and gynecology 1978;52(3):314-7.
1978: Rutanen E M; Lindgren J; Sipponen P; Stenman U P; Saksela E; Seppäla M
Carcinoembryonic antigen in malignant and nonmalignant gynecologic tumors: circulating levels and tissue localization.
Cancer 1978;42(2):581-90.
1978: Halme J; Ikonen M; Rutanen E M; Seppälä M
Gonadotropin receptors of human corpus luteum during menstrual cycle and pregnancy.
American journal of obstetrics and gynecology 1978;131(7):728-34.
1978: Kajanoja P; Ranta T; Seppälä M
Effect of prostaglandin F2alpha on ovarian and pituitary function in the mid-luteal phase.
Prostaglandins 1978;16(2):327-32.
1978: Seppälä M; Lehtovirta P; Rutanen E M
Detection of chorionic gonadotrophin like activity in infertile cycles with a short luteal phase.
Acta endocrinologica 1978;88(1):164-8.
1978: Lehtovirta P; Ranta T; Seppälä M
Pyridoxine treatment of galactorrhoea-amenorrhoea syndromes.
Acta endocrinologica 1978;87(4):682-6.
1978: Seppälä M
[Prolactin and its importance in the reproductive system]
Akusherstvo i ginekologiia 1978;(4):5-8.
1978: Seppälä M; Rutanen E M; Heikinheimo M; Jalanko H; Engvall E
Detection of trophoblastic tumour activity by pregnancy-specific beta-1-glycoprotein.
International journal of cancer. Journal international du cancer 1978;21(3):265-7.
1978: Rutanen E M; Seppälä M
The hCG-beta subunit radioimmunoassay in nontrophoblastic gynecologic tumors.
Cancer 1978;41(2):692-6.
1978: Seppälä M
Prolactin and female reproduction.
Annals of clinical research 1978;10(3):164-70.
1978: Koskimies A I; Hovatta O; Ranta T; Seppälä M
Serum and seminal plasma prolactin levels in oligospermia.
International journal of fertility 1978;23(1):76-8.
1977: Seppälä M; Lehtovirta P; Ranta T
Discordant patterns of hyperprolactinaemia and galactorrhoea in secondary amenorrhoea.
Acta endocrinologica 1977;86(3):457-63.
1977: Aula P; Karjalainen O; Rapola J; Lindgren J; Seppälä M
Prenatal diagnosis of the Meckel syndrome.
American journal of obstetrics and gynecology 1977;129(6):700-2.
1977: Seppälä M
Immunologic detection of alpha fetoprotein as a marker of fetal pathology.
Clinical obstetrics and gynecology 1977;20(3):737-57.
1977: Hirvonen E; Seppälä M; Karonen S L; Adlercreutz H
Luteinizing hormone responses to luteinizing hormone releasing hormone, and growth hormone and cortisol responses to insulin induced hypoglycaemia in functional secondary amenorrhoea.
Acta endocrinologica 1977;84(2):225-36.
1977: Seppälä M
[Diagnosis and treatment of uterine neoplasms]
Duodecim; lääketieteellinen aikakauskirja 1977;93(6):352-5.
1976: Garoff L; Seppälä M
Toxemia of pregnancy: assessment of fetal distress by urinary estriol and circulating human placental lactogen and alpha-fetoprotein levels.
American journal of obstetrics and gynecology 1976;126(8):1027-33.
1976: Seppälä M; Rutanen E M; Ranta T; Aho I; Nieminen U; Unnérus H A; Saksela E
Choriocarcinoma: expression of tumor- and trophoblast-associated antigens in patients with low chorionic gonadotropin excretion.
Cancer 1976;38(5):2065-70.
1976: Seppälä M; Unnérus H A; Hirvonen E; Ranta T
Bromocriptine increases plasma estradiol-17 beta concentration in amenorrhea patients with normal serum prolactin.
The Journal of clinical endocrinology and metabolism 1976;43(2):474-7.
1976: Vuento M; Engvall E; Seppälä M; Ruoslahti E
Isolation from human gastric juice of an antigen closely related to the carcinoembryonic antigen.
International journal of cancer. Journal international du cancer 1976;18(2):156-60.
1976: Seppälä M; Hirvonen E; Unnérus H A; Ranta T; Laatikainen T
Prolactin and testosterone: independent circulating levels in hyperprolactinemic and normoprolactinemic amenorrhea. The effect of prolactin suppression by bromocriptine.
The Journal of clinical endocrinology and metabolism 1976;43(1):198-200.
1976: Seppälä M; Rapola J; Huttunen N P; Aula P; Karjalainen O; Ruoslahti E
Congenital nephrotic syndrome: prenatal diagnosis and genetic counselling by estimation of aminotic-fluid and maternal serum alpha-fetoprotein.
Lancet 1976;2(7977):123-5.
1976: Hirvonen E; Ranta T; Seppäla M
Prolactin and thyrotropin responses to thyrotropin-releasing hormone in patients with secondary amenorrhea: the effect of bromocriptine.
The Journal of clinical endocrinology and metabolism 1976;42(6):1024-30.
1976: Seppalå M; Hirvonen E; Ranta T
Bromocriptine treatment of secondary amenorrhoea.
Lancet 1976;1(7970):1154-6.
1976: Seppälä M; Karjalainen O; Rapola J; Lindgren J
Letter: Maternal alpha-fetoprotein and fetal exomphalos.
Lancet 1976;1(7954):303-4.
1976: Seppälä M; Ranta T; Hirvonen E
Hyperprolactinaemia and luteal insufficiency.
Lancet 1976;1(7953):229-30.
1976: Leppäluoto J; Mäkelä O; Seppälä M
[Biologically active peptides]
Duodecim; lääketieteellinen aikakauskirja 1976;92(22):1261-4.
1976: Seppälä M; Ruoslahti E
Alpha-fetoprotein.
Contributions to gynecology and obstetrics 1976;2():143-86.
1976: Seppälä M
The use of alpha fetoprotein in prenatal diagnosis.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 1976;14(4):308-13.
1975: Seppälä M; Hirvonen E
Raised serum prolactin levels associated with hirsutism and amenorrhoea.
British medical journal 1975;4(5989):144-5.
1975: Seppälä M
Fetal pathophysiology of human alpha-fetoprotein.
Annals of the New York Academy of Sciences 1975;259():59-73.
1975: Seppala M; Hibroven E; Ranta T; Virkkunen P; Leppaluoto J
Raised serum prolactin levels in amenorrhoea.
British medical journal 1975;2(5966):305-6.
1975: Seppälä M; Pihko H; Ruoslahti E
Carcinoembryonic antigen and alpha fetoprotein in malignant tumors of the female genital tract.
Cancer 1975;35(5):1377-81.
1975: Rapola J; Aula P; Huttunen N; Seppälä M
Letter: Antenatal diagnosis of congenital nephrosis.
Lancet 1975;1(7913):981.
1975: Garoff L; Seppälä M
Prediction of fetal outcome in threatened abortion by maternal serum placental lactogen and alpha fetoprotein.
American journal of obstetrics and gynecology 1975;121(2):257-61.
1975: Seppälä M
[Prolactin]
Duodecim; lääketieteellinen aikakauskirja 1975;91(24):1525-35.
1975: Aula P; Karjalainen O; Seppälä M
[Amniotic fluid analysis in the early diagnosis of fetal abnormalities.]
Duodecim; lääketieteellinen aikakauskirja 1975;91(18):1064-76.
1975: Seppälä M; Aho I
Physiological role of meconium during delivery.
Acta obstetricia et gynecologica Scandinavica 1975;54(3):209-11.
1974: Kajanoja P; Junger G; Seppälä M; Karjalainen O; Widholm O
Prostaglandin induction of 424 midtrimester abortions.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 1974;12(6):198-203.
1974: Virkkunen P; Lybeck H; Partanen J; Ranta T; Leppäluoto J; Seppälä M
Plasma disapperance of injected synthetic LRH in man as measured by bioassay and radioimmunoassay.
The Journal of clinical endocrinology and metabolism 1974;39(4):702-5.
1974: Seppälä M; Laes E; Harvo-Noponen M
Elevated amniotic alpha-fetoprotein congenital oesophageal atresia.
The Journal of obstetrics and gynaecology of the British Commonwealth 1974;81(10):827-8.
1974: Seppälä M
Alpha-fetoprotein in the management of high-risk pregnancies.
Clinics in perinatology 1974;1(2):293-300.
1974: Ruoslahti E; Salaspuro M; Pihko H; Andersson L; Seppälä M
Serum alpha-fetoprotein: diagnostic significance in liver disease.
British medical journal 1974;2(5918):527-9.
1974: Seppälä M; Unnérus H A
Elevated amniotic fluid alpha fetoprotein in fetal hydrocephaly.
American journal of obstetrics and gynecology 1974;119(2):270-2.
1974: Kajanoja P; Jungner G; Widholm O; Karjalainen O; Seppälä M
Rupture of the cervix in prostaglandin abortions.
The Journal of obstetrics and gynaecology of the British Commonwealth 1974;81(3):242-4.
1974: Harris R; Jennison R F; Barson A J; Laurence K M; Ruoslahti E; Seppälä M
Comparison of amniotic-fluid and maternal serum alpha-fetoprotein levels in the early antenatal diagnosis of spina bifida and anencephaly.
Lancet 1974;1(7855):428-9.
1974: Seppälä M; Vaheri A
Natural rubella infection of the female genital tract.
Lancet 1974;1(7846):46-7.
1974: Kajanoja P; Jungner G; Seppälä M; Karjalainen O; Widholm O
Prostaglandin induction of midtrimester abortions: three years' experience of 626 cases.
Acta obstetricia et gynecologica Scandinavica. Supplement 1974;(37):51-6.
1974: Ruoslahti E; Pihko H; Vaheri A; Seppälä M; Virolainen M; Konttinen A
Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury.
Johns Hopkins medical journal. Supplement 1974;3():249-55.
1974: Ruoslahti E; Pihko H; Seppälä M
Alpha-fetoprotein: immunochemical purification and chemical properties. Expression in normal state and in malignant and non-malignant liver disease.
Transplantation reviews 1974;20(0):38-60.
1973: Seppälä M; Ruoslahti E
Alpha-fetoprotein in Rh-immunized pregnancies.
Obstetrics and gynecology 1973;42(5):701-6.
1973: Laurence K M; Turnbull A C; Harris R; Jennison R F; Ruoslahti E; Seppälä M
Letter: Antenatal diagnosis of spina bifida.
Lancet 1973;2(7833):860.
1973: Seppälä M
Increased alpha fetoprotein in amniotic fluid associated with a congenital esophageal atresia of the fetus.
Obstetrics and gynecology 1973;42(4):613-4.
1973: Garoff L; Seppälä M
Alpha fetoprotein and human placental lactogen levels in maternal serum in multiple pregnancies.
The Journal of obstetrics and gynaecology of the British Commonwealth 1973;80(8):695-700.
1973: Saarikoski S; Seppälä M
Immunosuppression during pregnancy: transmission of azathioprine and its metabolites from the mother to the fetus.
American journal of obstetrics and gynecology 1973;115(8):1100-6.
1973: Seppälä M; Renkonen O V; Vara P
Extra-amniotic prostaglandin-oxytocin abortion: comparison with the intra-amniotic method.
Prostaglandins 1973;3(1):17-28.
1973: Seppala M; Ruoslahti E
Alpha-fetoprotein in antenatal diagnosis.
Lancet 1973;1(7795):155.
1973: Seppälä M; Ruoslahti E
Alpha fetoprotein in maternal serum: a new marker for detection of fetal distress and intrauterine death.
American journal of obstetrics and gynecology 1973;115(1):48-52.
1973: Seppälä M
Alpha fetoprotein levels in women taking oral contraceptives.
International journal of fertility 1973;18(4):206-8.
1973: Seppälä M; Ruoslahti E
Alpha fetoprotein: Physiology and pathology during pregnancy and application to antenatal diagnosis.
Journal of perinatal medicine 1973;1(2):104-13.
1973: Seppälä M
[Alpha 1-fetoprotein in obstetrics]
Duodecim; lääketieteellinen aikakauskirja 1973;89(20):1353-4.
1973: Ruoslahti E; Seppälä M; Räsänen J A; Vuopio P; Helske T
Alpha-fetoprotein and hepatitis B antigen in acute hepatitis and primary cancer of the liver.
Scandinavian journal of gastroenterology 1973;8(3):197-202.
1972: Seppälä M; Ruoslahti E
Alpha-fetoprotein in abortion.
British medical journal 1972;4(5843):769-71.
1972: Seppälä M; Aho I; Tissari A; Ruoslahti E
Radioimmunoassay of oxytocin in amniotic fluid, fetal urine, and meconium during late pregnancy and delivery.
American journal of obstetrics and gynecology 1972;114(6):788-95.
1972: Seppälä M; Bagshawe K D; Ruoslahti E
Radioimmunoassay of alpha-fetoprotein: a contribution to the diagnosis of choriocarcinoma and hydatidiform mole.
International journal of cancer. Journal international du cancer 1972;10(3):478-81.
1972: Seppälä M; Ruoslahti E
Alpha fetoprotein in amniotic fluid: an index of gestational age.
American journal of obstetrics and gynecology 1972;114(5):595-8.
1972: Seppälä M; Kajanoja P; Widholm O; Vara P
Prostaglandin-oxytocin abortion: a clinical trial of intra-amniotic prostaglandin F2alpha in combination with intravenous oxytocin.
Prostaglandins 1972;2(4):311-9.
1972: Ruoslahti E; Seppälä M; Vuopio P; Saksela E; Peltokallio P
[Radioimmunoassay of alpha-fetoprotein in primary and secondary cancer of the liver.]
Journal of the National Cancer Institute 1972;49(3):623-30.
1972: Ruoslahti E; Seppälä M
Normal and increased alpha-fetoprotein in neoplastic and non-neoplastic liver disease.
Lancet 1972;2(7771):278-9.
1972: Seppälä M; Aho I; Widholm O; Ruoslahti E
Alpha fetoprotein in uterine hemorrhage during pregnancy and delivery.
American journal of obstetrics and gynecology 1972;113(3):323-8.
1972: Vaheri A; Vesikari T; Oker-Blom N; Seppala M; Parkman P D; Veronelli J; Robbins F C
Isolation of attenuated rubella-vaccine virus from human products of conception and uterine cervix.
The New England journal of medicine 1972;286(20):1071-4.
1972: Seppälä M; Vara P
Prostaglandin-oxytocin enhancement.
British medical journal 1972;1(5802):747.
1972: Seppälä M; Ruoslahti E
Alpha-fetoprotein in normal and pregnancy sera.
Lancet 1972;1(7746):375-6.
1972: Ruoslahti E; Seppälä M
-Foetoprotein in normal human serum.
Nature 1972;235(5334):161-2.
1972: Seppälä M; Ruoslahti E
Radioimmunoassay of maternal serum alpha fetoprotein during pregnancy and delivery.
American journal of obstetrics and gynecology 1972;112(2):208-12.
1972: Seppälä M
[Prostaglandins and abortion]
Duodecim; lääketieteellinen aikakauskirja 1972;88(17):1029-31.
1972: Ruoslahti E; Seppälä M
[Alpha-fetoprotein--a carcinoembryonal antigen]
Duodecim; lääketieteellinen aikakauskirja 1972;88(17):1033-43.
1971: Ruoslahti E; Seppälä M
Studies of carcino-fetal proteins. 3. Development of a radioimmunoassay for -fetoprotein. Demonstration of -fetoprotein in serum of healthy human adults.
International journal of cancer. Journal international du cancer 1971;8(3):374-83.
1971: Ruoslahti E; Seppälä M; Pihko H; Vuopio P
Studies of carcino-fetal proteins. II. Biochemical comparison of -fetoprotein from human fetuses and patients with hepatocellular cancer.
International journal of cancer. Journal international du cancer 1971;8(2):283-8.
1971: Fuchs F; Räihä N C; Seppälä M
Ethanol administration in premature labour.
Lancet 1971;2(7719):312-3.
1971: Seppälä M; Räihä N C; Tamminen V
Ethanol elimination in a mother and her premature twins.
Lancet 1971;1(7710):1188-9.
1971: Ruoslahti E; Seppälä M
Studies of carcino-fetal proteins: physical and chemical properties of human alpha-fetoprotein.
International journal of cancer. Journal international du cancer 1971;7(2):218-25.
1971: Seppälä M; Vara P
Standardization of the results of Shirodkar's operation.
Acta obstetricia et gynecologica Scandinavica. Supplement 1971;9():Suppl 9:66.
1971: Seppälä M; Saksela E
Placental haemangiomatosis and severe maternal eclampsia.
Acta obstetricia et gynecologica Scandinavica 1971;50(4):397-9.
1971: Seppälä M; Vihko R
[Lactation and its disturbances]
Duodecim; lääketieteellinen aikakauskirja 1971;87(6):478-84.
1970: Ikonen E; Merikallio E; Osterlund K; Seppälä M
Mitral-valve prosthesis, warfarin anticoagulation, and pregnancy.
Lancet 1970;2(7685):1252.
1970: Seppälä M; Tolonen M
Histocompatibility and human placentation.
Nature 1970;225(5236):950-1.
1970: Seppälä M; Vara P
Cervical cerclage in the treatment of incompetent cervix. A retrospective analysis of the indications and results of 164 operations.
Acta obstetricia et gynecologica Scandinavica 1970;49(4):343-6.
1970: Seppälä M
[Antibiotics during pregnancy and puerperium]
Duodecim; lääketieteellinen aikakauskirja 1970;86(4):237-41.
1970: Seppälä M; Ruoslahti E
Serum concentration of human placental lactogenic hormone (HPL) in pregnancy complications.
Acta obstetricia et gynecologica Scandinavica 1970;49(2):143-7.
1970: Seppälä M; Seppälä I J
Immunochemical determination of serum transferrin in patients with anaemia of pregnancy.
Annales chirurgiae et gynaecologiae Fenniae 1970;59(2):76-9.
1970: Seppälä M; Ruoslahti E; Soikkeli S; Tukiainen P
Effect of cyclophosphamide on serum immunoglobulin level in patients with tumours of the genital tract.
Annales medicinae experimentalis et biologiae Fenniae 1970;48(3):131-4.
1969: Vaheri A; Vesikari T; Oker-Blom N; Seppala M; Veronelli J; Robbins F C; Parkman P D
Transmission of attenuated rubella vaccines to the human fetus. A preliminary report.
American journal of diseases of children (1960) 1969;118(2):243-6.
1969: Kaivola S; Seppälä M; Seppälä I J
The effect of human serum on the activity of human pituitary (HPG) and menopausal (HMG) gonadotrophins in bioassay.
Annales medicinae experimentalis et biologiae Fenniae 1969;47(1):43-7.
1969: Seppälä M; Seppälä I J
Studies of a foeto-specific protein in rabbits. Absence of its relation to the human alpha-foetoprotein.
Annales chirurgiae et gynaecologiae Fenniae 1969;58(1):76-9.
1969: Tiilikainen A; Ruoslahti E; Seppälä M; Mårtensson L; Van Loghem E
Low frequency of genetic factors (gm(s) and Di(a) in Finland.
Human heredity 1969;19(2):180-4.
1968: Ruoslahti E; Seppälä I J; Simons K; Seppälä M
Identity of transferrin DChi from the Chinese and from the Finns.
Nature 1968;220(5166):480-1.
1968: Harvo-Noponen M; Seppälä M
Double blind study of oral chymotrypsin in patients with episiotomy.
Annales chirurgiae et gynaecologiae Fenniae 1968;57(4):444-6.
1968: Linder E; Seppälä M
Localization of alpha-foetoprotein in the human foetus and placenta.
Acta pathologica et microbiologica Scandinavica 1968;73(4):565-71.
1967: Seppälä M; Ruoslahti E; Seppälä I J
Transferrin system in paternity cases. An immunological verification test for heterozygosity.
Annales medicinae experimentalis et biologiae Fenniae 1967;45(1):14-5.
1967: Ehnholm C; Seppälä M; Tallberg T; Widholm O
Immunological studies in human placental lactogen hormone in chorionepithelioma and hydatiform mole.
Annales medicinae experimentalis et biologiae Fenniae 1967;45(3):318-9.
1967: Seppälä M; Tallberg T; Ehnholm C
Studies on embryo-specific proteins. Physiological characteristics of embryo-specific alpha-globulin.
Annales medicinae experimentalis et biologiae Fenniae 1967;45(1):16-9.
1966: Ruoslahti E; Tallberg T; Seppala M
Origin of proteins in amniotic fluid.
Nature 1966;212(5064):841.
1966: Seppälä M; Ruoslahti E; Tallberg T
Genetical evidence for maternal origin of amniotic fluid proteins.
Annales medicinae experimentalis et biologiae Fenniae 1966;44(1):6-7.
1965: Seppälä M
Distribution of serum transferrin groups in Finland and their inheritance.
Annales medicinae experimentalis et biologiae Fenniae 1965;43():Suppl 4:1-40.
1962: RENKONEN K O; SEPPALA M
The sex of the immunizing Rhpositive child.
Annales medicinae experimentalis et biologiae Fenniae 1962;40():108-9.

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