FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Edward LeCluyse

Research Profile

Anatomy

Chemicals & Drugs

Living Beings

Rats

Physiology

Concepts & Ideas

Procedures

Cell Culture Techniques

Co-author Network

Publications

TOP 3
Stephanie M Martinez; Blair U Bradford; Valerie Y Soldatow; Oksana Kosyk; Amelia Sandot; Rafal Witek; Robert Kaiser; Todd Stewart; Kirsten Amaral; Kimberly Freeman; Chris Black; Edward LeCluyse; Stephen S Ferguson; Ivan Rusyn
Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity.
Jasminder Sahi; Stacy S Shord; Celeste Lindley; Stephen Ferguson; Edward LeCluyse
Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Haizhen Zhu; John Elyar; Robin Foss; Alan Hemming; Eric Hall; Edward LeCluyse; Chen Liu
Primary human hepatocyte culture for HCV study.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Edward LeCluyse (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2010: Stephanie M Martinez; Blair U Bradford; Valerie Y Soldatow; Oksana Kosyk; Amelia Sandot; Rafal Witek; Robert Kaiser; Todd Stewart; Kirsten Amaral; Kimberly Freeman; Chris Black; Edward LeCluyse; Stephen S Ferguson; Ivan Rusyn
Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity.
Toxicology and applied pharmacology 2010;249(3):208-16.
2009: Jasminder Sahi; Stacy S Shord; Celeste Lindley; Stephen Ferguson; Edward LeCluyse
Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Journal of biochemical and molecular toxicology 2009;23(1):43-58.
2009: Haizhen Zhu; John Elyar; Robin Foss; Alan Hemming; Eric Hall; Edward LeCluyse; Chen Liu
Primary human hepatocyte culture for HCV study.
Methods in molecular biology (Clifton, N.J.) 2009;510():373-82.
2008: Rajgopal Govindarajan; Christopher J Endres; Dale Whittington; Edward LeCluyse; Marçal Pastor-Anglada; Chung-Ming Tse; Jashvant D Unadkat
Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(3):G570-80.
2008: Eliane Wauthier; Eva Schmelzer; William Turner; Lili Zhang; Edward LeCluyse; Joseph Ruiz; Rachael Turner; Mark E Furth; Hiroshi Kubota; Oswaldo Lozoya; Claire Barbier; Randall McClelland; Hsin-lei Yao; Nicholas Moss; Andrew Bruce; John Ludlow; Lola M Reid
Hepatic stem cells and hepatoblasts: identification, isolation, and ex vivo maintenance.
Methods in cell biology 2008;86():137-225.
2007: N J Hewitt; Edward LeCluyse; S S Ferguson
Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations.
Xenobiotica; the fate of foreign compounds in biological systems 2007;37(10-11):1196-224.
2007: Nicola J Hewitt; Ruben de Kanter; Edward LeCluyse
Induction of drug metabolizing enzymes: a survey of in vitro methodologies and interpretations used in the pharmaceutical industry--do they comply with FDA recommendations?
Chemico-biological interactions 2007;168(1):51-65.
2007: Nicola J Hewitt; María José Gómez Lechón; J Brian Houston; David Hallifax; Hayley S Brown; Patrick Maurel; J Gerald Kenna; Lena Gustavsson; Christina Lohmann; Christian Skonberg; André Guillouzo; Gregor Tuschl; Albert P Li; Edward LeCluyse; Geny M M Groothuis; Jan G Hengstler
Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.
Drug metabolism reviews 2007;39(1):159-234.
2007: Stephanie R Faucette; Tong-Cun Zhang; Rick Moore; Tatsuya Sueyoshi; Curtis J Omiecinski; Edward LeCluyse; Masahiko Negishi; Hongbing Wang
Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
The Journal of pharmacology and experimental therapeutics 2007;320(1):72-80.
2006: Deshi Shi; Jian Yang; Dongfang Yang; Edward LeCluyse; Chris Black; Li You; Fatemeh Akhlaghi; Bingfang Yan
Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel.
The Journal of pharmacology and experimental therapeutics 2006;319(3):1477-84.
2006: Man Tang; Madhu Mukundan; Jian Yang; Nathan Charpentier; Edward LeCluyse; Chris Black; Dongfang Yang; Deshi Shi; Bingfang Yan
Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol.
The Journal of pharmacology and experimental therapeutics 2006;319(3):1467-76.
2006: Richard A Graham; Bryan Goodwin; Raymond V Merrihew; Wojciech L Krol; Edward LeCluyse
Cloning, tissue expression, and regulation of beagle dog CYP4A genes.
Toxicological sciences : an official journal of the Society of Toxicology 2006;92(2):356-67.
2006: Schroeder M Noble; Virginia E Carnahan; Linda B Moore; Tom Luntz; Hongbing Wang; Olivia R Ittoop; Julie B Stimmel; Paula R Davis-Searles; Ryan E Watkins; G Bruce Wisely; Edward LeCluyse; Ashutosh Tripathy; Donald P McDonnell; Matthew R Redinbo
Human PXR forms a tryptophan zipper-mediated homodimer.
Biochemistry 2006;45(28):8579-89.
2006: Stephanie R Faucette; Tatsuya Sueyoshi; Cornelia M Smith; Masahiko Negishi; Edward LeCluyse; Hongbing Wang
Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1200-9.
2006: Richard A Graham; Lindsey O Tyler; Wojciech L Krol; Ivin S Silver; Lindsey O Webster; Philip Clark; Liangfu Chen; Troy Banks; Edward LeCluyse
Temporal kinetics and concentration-response relationships for induction of CYP1A, CYP2B, and CYP3A in primary cultures of beagle dog hepatocytes.
Journal of biochemical and molecular toxicology 2006;20(2):69-78.
2005: Cornelia M Smith; Richard A Graham; Wojciech L Krol; Ivin S Silver; Masahiko Negishi; Hongbing Wang; Edward LeCluyse
Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.
The Journal of pharmacology and experimental therapeutics 2005;315(3):1256-64.
2005: Stephen S Ferguson; Yuping Chen; Edward LeCluyse; Masahiko Negishi; Joyce A Goldstein
Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Molecular pharmacology 2005;68(3):747-57.
2005: Cornelia M Smith; Stephanie R Faucette; Hongbing Wang; Edward LeCluyse
Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers.
Journal of biochemical and molecular toxicology 2005;19(2):96-108.
2005: Edward LeCluyse; Eliane Alexandre; Geraldine A Hamilton; Catherine Viollon-Abadie; D James Coon; Summer Jolley; Lysiane Richert
Isolation and culture of primary human hepatocytes.
Methods in molecular biology (Clifton, N.J.) 2005;290():207-29.
2004: Zuzana Drobna; Stephen B Waters; Felecia S Walton; Edward LeCluyse; David J Thomas; Miroslav Styblo
Interindividual variation in the metabolism of arsenic in cultured primary human hepatocytes.
Toxicology and applied pharmacology 2004;201(2):166-77.
2004: Nadine Hempel; Hongbing Wang; Edward LeCluyse; Michael E McManus; Masahiko Negishi
The human sulfotransferase SULT1A1 gene is regulated in a synergistic manner by Sp1 and GA binding protein.
Molecular pharmacology 2004;66(6):1690-701.
2004: Jasminder Sahi; Ralph H Stern; Mark A Milad; Kelly A Rose; Gordon Gibson; Xianxian Zheng; Linda Stilgenbauer; Nalini Sadagopan; Summer Jolley; Darryl Gilbert; Edward LeCluyse
Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(12):1370-6.
2004: Hongbing Wang; Stephanie R Faucette; Rick Moore; Tatsuya Sueyoshi; Masahiko Negishi; Edward LeCluyse
Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
The Journal of biological chemistry 2004;279(28):29295-301.
2004: Keith A Hoffmaster; Ryan Z Turncliff; Edward LeCluyse; Richard B Kim; Peter J Meier Abt; Kim L R Brouwer
P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide.
Pharmaceutical research 2004;21(7):1294-302.
2004: Jeffrey A Sunman; Roy L Hawke; Edward LeCluyse; Angela D M Kashuba
Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(3):359-63.
2004: Stephanie R Faucette; Hongbing Wang; Geraldine A Hamilton; Summer Jolley; Darryl Gilbert; Celeste Lindley; Bingfang Yan; Masahiko Negishi; Edward LeCluyse
Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(3):348-58.
2003: Gang Luo; Jianrong Lin; William D Fiske; Renke Dai; Tian J Yang; Sean Kim; Michael W Sinz; Edward LeCluyse; Eric Solon; James M Brennan; Irma H Benedek; Summer Jolley; Darryl Gilbert; Lifei Wang; Frank W Lee; Liang-Shang Gan
Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(9):1170-5.
2003: Jasminder Sahi; Mark A Milad; Xianxian Zheng; Kelly A Rose; Hongbing Wang; Linda Stilgenbauer; Darryl Gilbert; Summer Jolley; Ralph H Stern; Edward LeCluyse
Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor.
The Journal of pharmacology and experimental therapeutics 2003;306(3):1027-34.
2003: Timothy K Tippin; Geraldine Hamilton; Linda Moore; Elizabeth J Beaudet; Summer Jolley; Thomas A Brodie; Robert C Andrews; J David Becherer; Darryl L McDougald; Michael D Gaul; Debie J Hoivik; Kathy Mellon-Kusibab; Jurgen Lehmann; Steven A Kliewer; Steven Novick; Ron Laethem; Zhiyang Zhao; Edward LeCluyse
CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(7):870-7.
2003: Hongbing Wang; Stephanie R Faucette; Darryl Gilbert; Summer Jolley; Tatsuya Sueyoshi; Masahiko Negishi; Edward LeCluyse
Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(5):620-30.
2003: Hongbing Wang; Stephanie R Faucette; Tatsuya Sueyoshi; Rick Moore; Stephen Ferguson; Masahiko Negishi; Edward LeCluyse
A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
The Journal of biological chemistry 2003;278(16):14146-52.
2003: Jasminder Sahi; Christopher B Black; Geraldine A Hamilton; Xianxian Zheng; Summer Jolley; Kelly A Rose; Darryl Gilbert; Edward LeCluyse; Michael W Sinz
Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(4):439-46.
2003: Ajay Madan; Richard A Graham; Kathleen M Carroll; Daniel R Mudra; L Alayne Burton; Linda A Krueger; April Downey; Maciej Czerwinski; Jameson Forster; Maria D Ribadeneira; Liang-Shang Gan; Edward LeCluyse; Karl Zech; Philmore Robertson; Patrick Koch; Lida Antonian; Greg Wagner; Li Yu; Andrew Parkinson
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(4):421-31.
2003: Felecia S Walton; Stephen B Waters; Summer Jolley; Edward LeCluyse; David J Thomas; Miroslav Styblo
Selenium compounds modulate the activity of recombinant rat AsIII-methyltransferase and the methylation of arsenite by rat and human hepatocytes.
Chemical research in toxicology 2003;16(3):261-5.
2003: Hongbing Wang; Edward LeCluyse
Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.
Clinical pharmacokinetics 2003;42(15):1331-57.
2002: Stephen S Ferguson; Edward LeCluyse; Masahiko Negishi; Joyce A Goldstein
Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site.
Molecular pharmacology 2002;62(3):737-46.
2002: Celeste Lindley; Geraldine Hamilton; Jeannine S McCune; Stephanie R Faucette; Stacy S Shord; Roy L Hawke; Hongbing Wang; Darryl Gilbert; Summer Jolley; Bingfang Yan; Edward LeCluyse
The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(7):814-22.
2002: Gang Luo; Mark Cunningham; Sean Kim; Timothy C Burn; Jianrong Lin; Michael W Sinz; Geraldine Hamilton; Christopher Rizzo; Summer Jolley; Darryl Gilbert; April Downey; Daniel R Mudra; Richard Graham; Kathy Carroll; Jindong Xie; Ajay Madan; Andrew Parkinson; David D Christ; Bernard H Selling; Edward LeCluyse; Liang-Shang Gan
CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(7):795-804.
2002: Lysiane Richert; Delphine Binda; G Hamilton; Catherine Viollon-Abadie; Eliane Alexandre; D Bigot-Lasserre; Remi Bars; Philippe Coassolo; Edward LeCluyse
Evaluation of the effect of culture configuration on morphology, survival time, antioxidant status and metabolic capacities of cultured rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2002;16(1):89-99.
2001: R Susick; Nicholas Moss; H Kubota; Edward LeCluyse; G Hamilton; Tom Luntz; J Ludlow; Jeffrey Fair; David A Gerber; K Bergstrand; J White; A Bruce; O Drury; Sanjeev Gupta; Lola M Reid
Hepatic progenitors and strategies for liver cell therapies.
Annals of the New York Academy of Sciences 2001;944():398-419.
2001: Geraldine A Hamilton; Summer Jolley; Darryl Gilbert; D J Coon; S Barros; Edward LeCluyse
Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions.
Cell and tissue research 2001;306(1):85-99.
2001: Stephanie R Faucette; Roy L Hawke; Stacy S Shord; Edward LeCluyse; Celeste Lindley
Evaluation of the contribution of cytochrome P450 3A4 to human liver microsomal bupropion hydroxylation.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(8):1123-9.
2001: Edward LeCluyse
Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;13(4):343-68.
2001: P Chandra; Edward LeCluyse; Kim L R Brouwer
Optimization of culture conditions for determining hepatobiliary disposition of taurocholate in sandwich-cultured rat hepatocytes.
In vitro cellular & developmental biology. Animal 2001;37(6):380-5.
2001: Edward LeCluyse
Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.
Chemico-biological interactions 2001;134(3):283-9.
2001: T Lu; J Liu; Edward LeCluyse; Yu-sen Zhou; Ming-Liang Cheng; Michael P Waalkes
Application of cDNA microarray to the study of arsenic-induced liver diseases in the population of Guizhou, China.
Toxicological sciences : an official journal of the Society of Toxicology 2001;59(1):185-92.
2000: Jeannine S McCune; Roy L Hawke; Edward LeCluyse; Heidi H Gillenwater; G Hamilton; J Ritchie; Celeste Lindley
In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone.
Clinical pharmacology and therapeutics 2000;68(4):356-66.
2000: Stephanie R Faucette; Roy L Hawke; Edward LeCluyse; Stacy S Shord; Bingfang Yan; R M Laethem; Celeste Lindley
Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(10):1222-30.
2000: Miroslav Styblo; Luz M Del Razo; Libia Vega; Dori R Germolec; Edward LeCluyse; Geraldine A Hamilton; William Reed; C Wang; William R Cullen; David J Thomas
Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells.
Archives of toxicology 2000;74(6):289-99.
2000: Edward LeCluyse; J A Fix; K L Audus; J H Hochman
Regeneration and maintenance of bile canalicular networks in collagen-sandwiched hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2000;14(2):117-32.
2000: Edward LeCluyse; Joy A Ahlgren-Beckendorf; Kathy Carroll; Andrew Parkinson; J Johnson
Regulation of glutathione S-transferase enzymes in primary cultures of rat hepatocytes maintained under various matrix configurations.
Toxicology in vitro : an international journal published in association with BIBRA 2000;14(2):101-15.
2000: Jasminder Sahi; G Hamilton; Michael W Sinz; S Barros; S M Huang; L J Lesko; Edward LeCluyse
Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 2000;30(3):273-84.
2000: W Zhu; L Song; He Zhang; Lynn Matoney; Edward LeCluyse; Bingfang Yan
Dexamethasone differentially regulates expression of carboxylesterase genes in humans and rats.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(2):186-91.
2000: Edward LeCluyse; A Madan; G Hamilton; K Carroll; R DeHaan; A Parkinson
Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes.
Journal of biochemical and molecular toxicology 2000;14(4):177-88.
2000: Stacey A Jones; Linda B Moore; Jennifer L Shenk; G Bruce Wisely; Geraldine A Hamilton; David D McKee; NC Tomkinson; Edward LeCluyse; Millard H Lambert; Timothy M Willson; Steven A Kliewer; John T Moore
The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
Molecular endocrinology (Baltimore, Md.) 2000;14(1):27-39.
1999: D Z Liu; Edward LeCluyse; Dhiren R Thakker
Dodecylphosphocholine-mediated enhancement of paracellular permeability and cytotoxicity in Caco-2 cell monolayers.
Journal of pharmaceutical sciences 1999;88(11):1161-8.
1999: Edward LeCluyse; P Bullock; Ajay Madan; Kathy Carroll; Andrew Parkinson
Influence of extracellular matrix overlay and medium formulation on the induction of cytochrome P-450 2B enzymes in primary cultures of rat hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(8):909-15.
1999: Miroslav Styblo; Luz M Del Razo; Edward LeCluyse; Geraldine A Hamilton; C Wang; William R Cullen; David J Thomas
Metabolism of arsenic in primary cultures of human and rat hepatocytes.
Chemical research in toxicology 1999;12(7):560-5.
1999: X Liu; Edward LeCluyse; Kenneth Brouwer; Liang-Shang Gan; John J Lemasters; B Stieger; Peter J Meier Abt; Kim L R Brouwer
Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration.
The American journal of physiology 1999;277(1 Pt 1):G12-21.
1999: X Liu; J P Chism; Edward LeCluyse; Kenneth Brouwer; Kim L R Brouwer
Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(6):637-44.
1999: X Liu; Edward LeCluyse; Kenneth Brouwer; R M Lightfoot; J I Lee; Kim L R Brouwer
Use of Ca2+ modulation to evaluate biliary excretion in sandwich-cultured rat hepatocytes.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1592-9.
1999: Ajay Madan; R DeHaan; Daniel R Mudra; Kathy Carroll; Edward LeCluyse; Andrew Parkinson
Effect of cryopreservation on cytochrome P-450 enzyme induction in cultured rat hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(3):327-35.
1998: X Liu; Kim L R Brouwer; Liang-Shang Gan; Kenneth Brouwer; B Stieger; Peter J Meier Abt; K L Audus; Edward LeCluyse
Partial maintenance of taurocholate uptake by adult rat hepatocytes cultured in a collagen sandwich configuration.
Pharmaceutical research 1998;15(10):1533-9.
1996: L Liu; Edward LeCluyse; Jie Liu; Curtis D Klaassen
Sulfotransferase gene expression in primary cultures of rat hepatocytes.
Biochemical pharmacology 1996;52(10):1621-30.
1996: Edward LeCluyse; P L Bullock; A Parkinson; J H Hochman
Cultured rat hepatocytes.
Pharmaceutical biotechnology 1996;8():121-59.
1995: R C Wood; Edward LeCluyse; J A Fix
Assessment of a model for measuring drug diffusion through implant-generated fibrous capsule membranes.
Biomaterials 1995;16(12):957-9.
1994: Edward LeCluyse; K L Audus; J H Hochman
Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration.
The American journal of physiology 1994;266(6 Pt 1):C1764-74.
1994: J H Hochman; J A Fix; Edward LeCluyse
In vitro and in vivo analysis of the mechanism of absorption enhancement by palmitoylcarnitine.
The Journal of pharmacology and experimental therapeutics 1994;269(2):813-22.
1993: S C Sutton; Edward LeCluyse; K Engle; J D Pipkin; J A Fix
Enhanced bioavailability of cefoxitin using palmitoylcarnitine. II. Use of directly compressed tablet formulations in the rat and dog.
Pharmaceutical research 1993;10(10):1516-20.
1993: Edward LeCluyse; S C Sutton; J A Fix
In vitro effects of long-chain acylcarnitines on the permeability, transepithelial electrical resistance and morphology of rat colonic mucosa.
The Journal of pharmacology and experimental therapeutics 1993;265(2):955-62.
1992: S C Sutton; A E Forbes; R Cargill; J H Hochman; Edward LeCluyse
Simultaneous in vitro measurement of intestinal tissue permeability and transepithelial electrical resistance (TEER) using Sweetana-Grass diffusion cells.
Pharmaceutical research 1992;9(3):316-9.
1992: S C Sutton; Edward LeCluyse; L Cammack; J A Fix
Enhanced bioavailability of cefoxitin using palmitoyl L-carnitine. I. Enhancer activity in different intestinal regions.
Pharmaceutical research 1992;9(2):191-4.
1991: Edward LeCluyse; L E Appel; S C Sutton
Relationship between drug absorption enhancing activity and membrane perturbing effects of acylcarnitines.
Pharmaceutical research 1991;8(1):84-7.
1987: Mary L Michaelis; T E Kitos; E W Nunley; Edward LeCluyse; Elias K Michaelis
Characteristics of Mg2+-dependent, ATP-activated Ca2+ transport in synaptic and microsomal membranes and in permeabilized synaptosomes.
The Journal of biological chemistry 1987;262(9):4182-9.
1987: R W Portman; Edward LeCluyse; W L Dentler
Development of microtubule capping structures in ciliated epithelial cells.
Journal of cell science 1987;87 ( Pt 1)():85-94.
1987: Elias K Michaelis; S Roy; N Galton; M Cunningham; Edward LeCluyse; M Michaelis
Correlation of glutamate binding activity with glutamate-binding protein immunoreactivity in the brain of control and alcohol-treated rats.
Neurochemistry international 1987;11(2):209-18.
1985: Kathy A Suprenant; E Hays; Edward LeCluyse; W L Dentler
Multiple forms of tubulin in the cilia and cytoplasm of Tetrahymena thermophila.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(20):6908-12.
1985: Edward LeCluyse; S K Frost; W L Dentler
Development and ciliation of the palate in two frogs, Bombina and Xenopus; a comparative study.
Tissue & cell 1985;17(6):853-64.
1984: Edward LeCluyse; W L Dentler
Asymmetrical microtubule capping structures in frog palate cilia.
Journal of ultrastructure research 1984;86(1):75-85.
1982: W L Dentler; Edward LeCluyse
Microtubule capping structures at the tips of tracheal cilia: evidence for their firm attachment during ciliary bend formation and the restriction of microtubule sliding.
Cell motility 1982;2(6):549-72.
1982: W L Dentler; Edward LeCluyse
The effects of structures attached to the tips of tracheal ciliary microtubules on the nucleation of microtubule assembly in vitro.
Progress in clinical and biological research 1982;80():13-8.
1981: R F Sattilaro; W L Dentler; Edward LeCluyse
Microtubule-associated proteins (MAPs) and the organization of actin filaments in vitro.
The Journal of cell biology 1981;90(2):467-73.