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Xuezhong Yu

Research Profile

Living Beings

Disorders

Graft vs Host Disease

Physiology

Lymphocyte Activation

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T-Lymphocyte Subsets

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Publications

TOP 3
Dapeng Wang; Changqing Xia; Claudio Anasetti; Cristina Iclozan; Chen Liu; Xuezhong Yu
LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice.
Cristina Iclozan; Yu Yu; Chen Liu; Yaming Liang; Tangsheng Yi; Claudio Anasetti; Xuezhong Yu
T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease.
Javier O Valenzuela; Cristina Iclozan; Mohammad S Hossain; Martin Prlic; Emily Hopewell; Crystina C Bronk; Junmei Wang; Esteban Celis; Robert W Engelman; Bruce R Blazar; Michael J Bevan; Edmond WALLER; Xuezhong Yu; Amer A Beg
PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice.

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All Publications

2012: Dapeng Wang; Changqing Xia; Claudio Anasetti; Cristina Iclozan; Chen Liu; Xuezhong Yu
LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012;18(8):1182-1190.e1.
2010: Cristina Iclozan; Yu Yu; Chen Liu; Yaming Liang; Tangsheng Yi; Claudio Anasetti; Xuezhong Yu
T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(2):170-8.
2009: Javier O Valenzuela; Cristina Iclozan; Mohammad S Hossain; Martin Prlic; Emily Hopewell; Crystina C Bronk; Junmei Wang; Esteban Celis; Robert W Engelman; Bruce R Blazar; Michael J Bevan; Edmond WALLER; Xuezhong Yu; Amer A Beg
PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice.
The Journal of clinical investigation 2009;119(12):3774-86.
2009: Yu Yu; Cristina Iclozan; Tomohide Yamazaki; Xuexian Yang; Claudio Anasetti; Chen Dong; Xuezhong Yu
Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death.
Blood 2009;114(5):1026-8.
2008: Michael H Albert; Xuezhong Yu; Thomas Magg
Ethylenecarbodiimide-coupled allogeneic antigen presenting cells induce human CD4+ regulatory T cells.
Clinical immunology (Orlando, Fla.) 2008;129(3):381-93.
2008: Fei Guo; Cristina Iclozan; Woong-Kyung Suh; Claudio Anasetti; Xuezhong Yu
CD28 controls differentiation of regulatory T cells from naive CD4 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2285-91.
2008: Honglin Wang; Thorsten Peters; Anca Sindrilaru; Daniel Kess; Tsvetelina Oreshkova; Xuezhong Yu; Anne Maria Seier; Heike Schreiber; Meinhard Wlaschek; Robert Blakytny; Jan Röhrbein; Guido Schulz; Johannes M Weiss; Karin Scharffetter-Kochanek
TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis.
The Journal of clinical investigation 2008;118(7):2629-39.
2008: Yaming Liang; Chen Liu; Julie Y Djeu; Bin Zhong; Thorsten Peters; Karin Scharffetter-Kochanek; Claudio Anasetti; Xuezhong Yu
Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects.
Blood 2008;111(2):954-62.
2006: Xuezhong Yu; Yaming Liang; Roza I Nurieva; Fei Guo; Claudio Anasetti; Chen Dong
Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7394-401.
2006: Roza I Nurieva; Sunil Thomas; Thang Nguyen; Natalia Martin-Orozco; Ying Wang; Murali-Krishna Kaja; Xuezhong Yu; Chen Dong
T-cell tolerance or function is determined by combinatorial costimulatory signals.
The EMBO journal 2006;25(11):2623-33.
2006: Michael H Albert; Claudio Anasetti; Xuezhong Yu
T regulatory cells as an immunotherapy for transplantation.
Expert opinion on biological therapy 2006;6(4):315-24.
2006: Xuezhong Yu; Michael H Albert; Claudio Anasetti
Alloantigen affinity and CD4 help determine severity of graft-versus-host disease mediated by CD8 donor T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3383-90.
2005: Xuezhong Yu; Claudio Anasetti
Memory stem cells sustain disease.
Nature medicine 2005;11(12):1282-3.
2005: Michael H Albert; Yan Liu; Claudio Anasetti; Xuezhong Yu
Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation.
European journal of immunology 2005;35(9):2598-607.
2005: Michael H Albert; Xuezhong Yu; Paul J Martin; Claudio Anasetti
Prevention of lethal acute GVHD with an agonistic CD28 antibody and rapamycin.
Blood 2005;105(3):1355-61.
2004: Xuezhong Yu; Michael H Albert; Paul J Martin; Claudio Anasetti
CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens.
The Journal of clinical investigation 2004;113(11):1624-30.
2004: Xuezhong Yu; Steven D Levin; Joaquín Madrenas; Claudio Anasetti
Lck is required for activation-induced T cell death after TCR ligation with partial agonists.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1437-43.
2003: Xuezhong Yu; Paul J Martin; Claudio Anasetti
CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3002-6.
2001: Xuezhong Yu; Y Nitta; SJ Bidwell; Claudio Anasetti
Additive effects of anti-CD3 and anti-CD28 prolongation of allogeneic skin graft survival.
Transplantation 2001;72(11):1862.
2001: Xuezhong Yu; Paul Carpenter; Claudio Anasetti
Advances in transplantation tolerance.
Lancet 2001;357(9272):1959-63.
2001: Xuezhong Yu; SJ Bidwell; Paul J Martin; Claudio Anasetti
Anti-CD3 epsilon F(ab')2 prevents graft-versus-host disease by selectively depleting donor T cells activated by recipient alloantigens.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(9):5835-9.
2000: Paul A Carpenter; S Pavlovic; J Y Tso; Oliver W Press; Ted Gooley; Xuezhong Yu; Claudio Anasetti
Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6205-13.
2000: Paul A Carpenter; J Y Tso; Oliver W Press; Xuezhong Yu; Claudio Anasetti
Non-FcR-binding, humanized anti-CD3 antibody Hu291 induces apoptosis of human T cells more effectively than OKT3 and is immunosuppressive in vivo.
Transplantation proceedings 2000;32(7):1545-6.
2000: Xuezhong Yu; SJ Bidwell; Paul J Martin; Claudio Anasetti
CD28-specific antibody prevents graft-versus-host disease in mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4564-8.
2000: Xuezhong Yu; Claudio Anasetti
Enhancement of susceptibility to Fas-mediated apoptosis of TH1 cells by nonmitogenic anti-CD3epsilon F(ab')2.
Transplantation 2000;69(1):104-12.
1999: Xuezhong Yu; SJ Bidwell; Paul J Martin; Claudio Anasetti
Visualization, fate, and pathogenicity of antigen-specific CD8+ T cells in the graft-versus-host reaction.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):4780-7.
1999: L Zhu; Xuezhong Yu; Y Akatsuka; J A Cooper; C Anasetti
Role of mitogen-activated protein kinases in activation-induced apoptosis of T cells.
Immunology 1999;97(1):26-35.
1998: Xuezhong Yu; Paul J Martin; Claudio Anasetti
Role of CD28 in acute graft-versus-host disease.
Blood 1998;92(8):2963-70.
1996: Xuezhong Yu; L Zhu; J E Davis; J Y Tso; John A Hansen; Claudio Anasetti
Induction of apoptosis by anti-CD3 epsilon F(ab')2 in antigen receptor transgenic murine T cells activated by specific peptide.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3420-9.
1996: N J Chalupny; L Zhu; Xuezhong Yu; Claudio Anasetti
Cell cycle control of T cell apoptosis induced by activation through the T cell antigen receptor.
Advances in experimental medicine and biology 1996;406():57-67.