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Jiri Cabal

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Jan Misik; Ruzena Pavlikova; Eva Vodakova; Jiri Cabal; Petr Jost; Kamil Kuca
A comparison of decontamination effects of commercially available detergents in rats pre-exposed to topical sulphur mustard.
Jan Misik; Ladislav Novotny; Michal Pavlik; Ruzena Pavlikova; Jiri Cabal; Robert P Chilcott; Kamil Kuca
In vivo decontamination of the nerve agent VX using the domestic swine model.
Jan Misik; Ruzena Pavlikova; Jiri Cabal; Denis Josse; Kamil Kuca
In vitro skin permeation and decontamination of the organophosphorus pesticide paraoxon under various physical conditions--evidence for a wash-in effect.

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2013: Jan Misik; Ruzena Pavlikova; Eva Vodakova; Jiri Cabal; Petr Jost; Kamil Kuca
A comparison of decontamination effects of commercially available detergents in rats pre-exposed to topical sulphur mustard.
Cutaneous and ocular toxicology 2013;32(2):135-9.
2012: Jan Misik; Ladislav Novotny; Michal Pavlik; Ruzena Pavlikova; Jiri Cabal; Robert P Chilcott; Kamil Kuca
In vivo decontamination of the nerve agent VX using the domestic swine model.
Clinical toxicology (Philadelphia, Pa.) 2012;50(9):807-11.
2012: Jan Misik; Ruzena Pavlikova; Jiri Cabal; Denis Josse; Kamil Kuca
In vitro skin permeation and decontamination of the organophosphorus pesticide paraoxon under various physical conditions--evidence for a wash-in effect.
Toxicology mechanisms and methods 2012;22(7):520-5.
2012: Jan Marek; Kamil Musilek; Ondrej Soukup; Petr Stodulka; Vladimir Buchta; Jiri Cabal; Kallol K Ghosh; Kamil Kuca
Preparation of quinolinium salts differing in the length of the alkyl side chain.
Molecules (Basel, Switzerland) 2012;17(6):6386-94.
2010: Jiri Cabal; Jiri Bajgar; Jirí Kassa
Evaluation of flow injection analysis for determination of cholinesterase activities in biological material.
Chemico-biological interactions 2010;187(1-3):225-8.
2010: Jiri Bajgar; Jana Zdarova Karasova; Jirí Kassa; Jiri Cabal; Josef Fusek; Vladimir Blaha; Sandra Tesarova
Tabun-inhibited rat tissue and blood cholinesterases and their reactivation with the combination of trimedoxime and HI-6 in vivo.
Chemico-biological interactions 2010;187(1-3):287-90.
2010: Kamil Kuca; Kamil Musilek; Kyung-Ae Oh; Jaroslav Pejchal; Miroslav Pohanka; Ondrej Soukup; Garp Yeol Yang; Jiri Cabal; Daniel Jun; Young-Sik Jung
Reactivation of VX-inhibited AChE by novel oximes having two oxygen atoms in the linker.
Environmental toxicology and pharmacology 2010;30(1):85-7.
2010: Jan Marek; Petr Stodulka; Jiri Cabal; Ondrej Soukup; Miroslav Pohanka; Jan Korabecny; Kamil Musilek; Kamil Kuca
Preparation of the pyridinium salts differing in the length of the N-alkyl substituent.
Molecules (Basel, Switzerland) 2010;15(3):1967-72.
2009: Kamil Kuca; Jiri Cabal; Yung Sik Jung; Kamil Musilek; Ondrej Soukup; Daniel Jun; Miroslav Pohanka; Lucie Musilova; Jana Karasová; Ladislav Novotný; Martina Hrabinova
Reactivation of human brain homogenate cholinesterases inhibited by Tabun using newly developed oximes K117 and K127.
Basic & clinical pharmacology & toxicology 2009;105(3):207-10.
2008: Kamil Kuca; Jiri Cabal; Daniel Jun; Vit Koleckar
In Vitro Comparison of Two Most Promising H-Oximes (HI-6 and HLö-7) and Currently Commercially Available Reactivators Pralidoxime and Obidoxime in Reactivation of Cyclosarin-Inhibited Human Cholinesterases.
Toxicology mechanisms and methods 2008;18(4):329-33.
2007: Kamil Musilek; Daniel Jun; Jiri Cabal; Jirí Kassa; Frank Gunn-Moore; Kamil Kuca
Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203).
Journal of medicinal chemistry 2007;50(22):5514-8.
2007: Jiri Bajgar; Kamil Kuca; Josef Fusek; Jana Karasova; Jirí Kassa; Jiri Cabal; Daniel Jun; Vladimir Blaha
Inhibition of blood cholinesterases following intoxication with VX and its derivatives.
Journal of applied toxicology : JAT 2007;27(5):458-63.
2007: Kamil Kuca; Daniel Jun; Jiri Cabal; Lucie Musilova
Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study.
Basic & clinical pharmacology & toxicology 2007;101(1):25-8.
2007: Kamil Kuca; Jiri Cabal; Daniel Jun; Martina Hrabinova
Potency of five structurally different acetylcholinesterase reactivators to reactivate human brain cholinesterases inhibited by cyclosarin.
Clinical toxicology (Philadelphia, Pa.) 2007;45(5):512-5.
2007: Kamil Kuca; Jiri Cabal; Daniel Jun; Kamil Musilek
In vitro reactivation potency of acetylcholinesterase reactivators--K074 and K075--to reactivate tabun-inhibited human brain cholinesterases.
Neurotoxicity research 2007;11(2):101-6.
2006: Kamil Kuca; Jiri Cabal; Daniel Jun; Jiri Bajgar; Martina Hrabinova
Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases.
Journal of enzyme inhibition and medicinal chemistry 2006;21(6):663-6.
2006: Jirí Kassa; Kamil Kuca; Jiri Cabal; Martin Paar
A comparison of the efficacy of new asymmetric bispyridinium oximes (K027, K048) with currently available oximes against tabun by in vivo methods.
Journal of toxicology and environmental health. Part A 2006;69(20):1875-82.
2006: Kamil Kuca; Jiri Cabal; Jirí Kassa; Daniel Jun; Martina Hrabinova
In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase.
Journal of toxicology and environmental health. Part A 2006;69(15):1431-40.
2006: Kamil Kuca; Daniel Jun; Jiri Cabal; Martina Hrabinova; Lucie Bartosova; Veronika Opletalova
Russian VX: inhibition and reactivation of acetylcholinesterase compared with VX agent.
Basic & clinical pharmacology & toxicology 2006;98(4):389-94.
2006: Kamil Kuca; Jiri Cabal; Daniel Jun; Martina Hrabinova
In vitro evaluation of acetylcholinesterase reactivators as potential antidotes against tabun nerve agent poisonings.
Drug and chemical toxicology 2006;29(4):443-9.
2005: Daniel Jun; Kamil Kuca; Jiri Cabal; Lucie Bartosova; Gabriela Kunesova; Jirí Kassa
Comparison of ability of some oximes to reactivate sarin-inhibited brain acetylcholinesterase from different species.
Chemico-biological interactions 2005;157-158():385-7.
2005: Kamil Kuca; Lucie Bartosova; Jirí Kassa; Jiri Cabal; Jiri Bajgar; Gabriela Kunesova; Daniel Jun
Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo.
Chemico-biological interactions 2005;157-158():367-8.
2005: Kamil Kuca; Jiri Cabal; Daniel Jun; Jirí Kassa; Lucie Bartosová; Gabriela Kunesová; Vlastimil Dohnal
Strategy for the development of new acetylcholinesterase reactivators - antidotes used for treatment of nerve agent poisonings.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005;149(2):429-31.
2005: Jirí Kassa; Kamil Kuca; Jiri Cabal
A comparison of the potency of trimedoxime and other currently available oximes to reactivate tabun-inhibited acetylcholinesterase and eliminate acute toxic effects of tabun.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005;149(2):419-23.
2005: Kamil Kuca; Jiri Cabal; Kamil Musilek; Daniel Jun; Jiri Bajgar
Effective bisquaternary reactivators of tabun-inhibited AChE.
Journal of applied toxicology : JAT 2005;25(6):491-5.
2005: Jiri Cabal; Kamil Kuca; Daniel Jun; Jiri Bajgar; Martina Hrabinová
[A comparison of the efficacy of the reactivators of acetylcholinesterase inhibited with tabun].
Ceská a Slovenská farmacie : casopis Ceské farmaceutické spolecnosti a Slovenské farmaceutické spolecnosti 2005;54(4):192-5.
2005: Kamil Kuca; Jiri Cabal; Daniel Jun; Jirí Kassa; Lucie Bartosová; Gabriela Kunesová
In vitro reactivation potency of some acetylcholinesterase reactivators against sarin- and cyclosarin-induced inhibitions.
Journal of applied toxicology : JAT 2005;25(4):296-300.
2005: Kamil Kuca; Jiri Cabal; Jirí Kassa; Daniel Jun; Martina Hrabinová
Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain.
Journal of applied toxicology : JAT 2005;25(4):271-6.
2005: Kamil Kuca; Lucie Bartosová; Daniel Jun; Jirí Patocka; Jiri Cabal; Jirí Kassa; Gabriela Kunesová
New quaternary pyridine aldoximes as casual antidotes against nerve agents intoxications.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005;149(1):75-82.
2005: Jan Picha; Kamil Kuca; Milan Kivala; Michal Kohout; Jiri Cabal; Frantisek Liska
A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents.
Journal of enzyme inhibition and medicinal chemistry 2005;20(3):233-7.
2005: Kamil Kuca; Jiri Cabal; Jirí Kassa
A comparison of the potency of newly developed oximes (K005, K027, K033, K048) and currently used oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited rat brain acetylcholinesterase by in vitro methods.
Journal of toxicology and environmental health. Part A 2005;68(8):677-86.
2005: Kamil Kuca; Jiri Cabal
Evaluation of newly synthesized reactivators of the brain cholinesterase inhibited by sarin nerve agent.
Toxicology mechanisms and methods 2005;15(4):247-52.
2005: Kamil Kuca; Jiri Cabal; Jirí Kassa; Daniel Jun; Martina Hrabinová
A comparison of the potency of the oxime HLö-7 and currently used oximes (HI-6, pralidoxime, obidoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2005;48(2):81-6.
2004: Jiri Cabal; Kamil Kuca; Jirí Kassa
Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase.
Basic & clinical pharmacology & toxicology 2004;95(2):81-6.
2004: Kamil Kuca; Jirí Patocka; Jiri Cabal; Daniel Jun
Reactivation of organophosphate-inhibited acetylcholinesterase by quaternary pyridinium aldoximes.
Neurotoxicity research 2004;6(7-8):565-70.
2004: Jiri Cabal; Kamil Kuca; Lucie Sevelová-Bartosová; Vlastimil Dohnal
Cyclodextrines as functional agents for decontamination of the skin contaminated by nerve agents.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2004;47(2):115-8.
2003: Kamil Kuca; Jirí Bielavský; Jiri Cabal; Jirí Kassa
Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase.
Bioorganic & medicinal chemistry letters 2003;13(20):3545-7.
2000: Jirí Patocka; Jirí Bielavský; Jiri Cabal; Josef Fusek
3-Nitropropionic acid and similar nitrotoxins.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2000;43(1):9-13.