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Carl Ware

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
23
Benedict, Chris
9
Norris, Paula
8
De Trez, Carl
7
Browning, Jeffrey
7
Croft, Michael
7
Rooney, IA
7
Walter, BN
7
Crowe, Paul
6
Santee, SM
6
Schneider, Kirsten
5
Spear, Patricia
5
Force, Walker
5
Granger, Steven
5
Cheung, Timothy
5
Butrovich, KD

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Publications

TOP 3
Zhao Yuan; De Trez Carl; Flynn Rachel; Ware Carl F; Croft Michael; Salek-Ardakani Shahram
The adaptor molecule MyD88 directly promotes CD8 T cell responses to vaccinia virus.
Ware Carl F
Targeting the LIGHT-HVEM Pathway.
Sedý John R; Spear Patricia G; Ware Carl F
Cross-regulation between herpesviruses and the TNF superfamily members.

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All Publications

2009: Zhao Yuan; De Trez Carl; Flynn Rachel; Ware Carl F; Croft Michael; Salek-Ardakani Shahram
The adaptor molecule MyD88 directly promotes CD8 T cell responses to vaccinia virus.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6278-86.
2009: Ware Carl F
Targeting the LIGHT-HVEM Pathway.
Advances in experimental medicine and biology 2009;647():146-55.
2008: Sedý John R; Spear Patricia G; Ware Carl F
Cross-regulation between herpesviruses and the TNF superfamily members.
Nature reviews. Immunology 2008;8(11):861-73.
2008: Ware Carl F
Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways.
Immunological reviews 2008;223():186-201.
2008: Ware Carl F
The TNF Superfamily-2008.
Cytokine & growth factor reviews 2008;19(3-4):183-6.
2008: Steinberg Marcos W; Turovskaya Olga; Shaikh Raziya B; Kim Gisen; McCole Declan F; Pfeffer Klaus; Murphy Kenneth M; Ware Carl F; Kronenberg Mitchell
A crucial role for HVEM and BTLA in preventing intestinal inflammation.
The Journal of experimental medicine 2008;205(6):1463-76.
2008: De Trez Carl; Ware Carl F
The TNF receptor and Ig superfamily members form an integrated signaling circuit controlling dendritic cell homeostasis.
Cytokine & growth factor reviews 2008;19(3-4):277-84.
2008: Dhawan Punita; Su Yingjun; Thu Yee Mon; Yu Yingchun; Baugher Paige; Ellis Darrel L; Sobolik-Delmaire Tammy; Kelley Mark; Cheung Timothy C; Ware Carl F; Richmond Ann
The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells.
The Journal of biological chemistry 2008;283(22):15399-408.
2008: Seach Natalie; Ueno Tomoo; Fletcher Anne L; Lowen Tamara; Mattesich Monika; Engwerda Christian R; Scott Hamish S; Ware Carl F; Chidgey Ann P; Gray Daniel H D; Boyd Richard L
The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5384-92.
2008: Schneider Kirsten; Loewendorf Andrea; De Trez Carl; Fulton James; Rhode Antje; Shumway Heather; Ha Sukwon; Patterson Ginelle; Pfeffer Klaus; Nedospasov Sergei A; Ware Carl F; Benedict Chris A
Lymphotoxin-mediated crosstalk between B cells and splenic stroma promotes the initial type I interferon response to cytomegalovirus.
Cell host & microbe 2008;3(2):67-76.
2008: Vu Frances; Dianzani Umberto; Ware Carl F; Mak Tak; Gommerman Jennifer L
ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2284-93.
2008: Nelson Christopher A; Fremont Marcel D; Sedy John R; Norris Paula S; Ware Carl F; Murphy Kenneth M; Fremont Daved H
Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):940-7.
2008: De Trez Carl; Schneider Kirsten; Potter Karen; Droin Nathalie; Fulton James; Norris Paula S; Ha Suk-won; Fu Yang-Xin; Murphy Theresa; Murphy Kenneth M; Pfeffer Klaus; Benedict Chris A; Ware Carl F
The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):238-48.
2007: Humphreys Ian R; Loewendorf Andrea; de Trez Carl; Schneider Kirsten; Benedict Chris A; Munks Michael W; Ware Carl F; Croft Michael
OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2195-202.
2007: Bécart Stéphane; Charvet Céline; Canonigo Balancio Ann J; De Trez Carl; Tanaka Yoshihiko; Duan Wei; Ware Carl; Croft Michael; Altman Amnon
SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
The Journal of clinical investigation 2007;117(8):2164-75.
2007: Taylor Joann M; Lin Erick; Susmarski Nanette; Yoon Miri; Zago Anna; Ware Carl F; Pfeffer Klaus; Miyoshi Jun; Takai Yoshimi; Spear Patricia G
Alternative entry receptors for herpes simplex virus and their roles in disease.
Cell host & microbe 2007;2(1):19-28.
2007: Humphreys Ian R; de Trez Carl; Kinkade April; Benedict Chris A; Croft Michael; Ware Carl F
Cytomegalovirus exploits IL-10-mediated immune regulation in the salivary glands.
The Journal of experimental medicine 2007;204(5):1217-25.
2007: Elewaut Dirk; Ware Carl F
The unconventional role of LT alpha beta in T cell differentiation.
Trends in immunology 2007;28(4):169-75.
2007: Basak Soumen; Kim Hana; Kearns Jeffrey D; Tergaonkar Vinay; O'Dea Ellen; Werner Shannon L; Benedict Chris A; Ware Carl F; Ghosh Gourisankar; Verma Inder M; Hoffmann Alexander
A fourth IkappaB protein within the NF-kappaB signaling module.
Cell 2007;128(2):369-81.
2007: Norris Paula S; Ware Carl F
The LT beta R signaling pathway.
Advances in experimental medicine and biology 2007;597():160-72.
2006: Zhu Mingzhao; Chin Robert K; Christiansen Peter A; Lo James C; Liu Xiaojuan; Ware Carl; Siebenlist Ulrich; Fu Yang-Xin
NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway.
The Journal of clinical investigation 2006;116(11):2964-71.
2006: Kinkade April; Ware Carl F
The DARC conspiracy--virus invasion tactics.
Trends in immunology 2006;27(8):362-7.
2006: Chin Robert K; Zhu Mingzhao; Christiansen Peter A; Liu Wenhua; Ware Carl; Peltonen Leena; Zhang Xuejun; Guo Linjie; Han Shuhua; Zheng Biao; Fu Yang-Xin
Lymphotoxin pathway-directed, autoimmune regulator-independent central tolerance to arthritogenic collagen.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):290-7.
2006: Benedict Chris A; De Trez Carl; Schneider Kirsten; Ha Sukwon; Patterson Ginelle; Ware Carl F
Specific remodeling of splenic architecture by cytomegalovirus.
PLoS pathogens 2006;2(3):e16.
2006: Schneider Kirsten; Benedict Chris A; Ware Carl F
A TRAFfic cop for host defense.
Nature immunology 2006;7(1):15-6.
2006: Banks Theresa A; Rickert Sandra; Ware Carl F
Restoring immune defenses via lymphotoxin signaling: lessons from cytomegalovirus.
Immunologic research 2006;34(3):243-54.
2006: Lurain Nell S; Fox Andrea M; Lichy Heather M; Bhorade Sangeeta M; Ware Carl F; Huang Diana D; Kwan Sau-Ping; Garrity Edward R; Chou Sunwen
Analysis of the human cytomegalovirus genomic region from UL146 through UL147A reveals sequence hypervariability, genotypic stability, and overlapping transcripts.
Virology journal 2006;3():4.
2005: Benedict Chris A; Ware Carl F
Poxviruses aren't stuPYD.
Immunity 2005;23(6):553-5.
2005: Iversen Ann-Charlotte; Norris Paula S; Ware Carl F; Benedict Chris A
Human NK cells inhibit cytomegalovirus replication through a noncytolytic mechanism involving lymphotoxin-dependent induction of IFN-beta.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7568-74.
2005: Nishimoto Hajime; Lee Seung-Woo; Hong Hong; Potter Karen G; Maeda-Yamamoto Mari; Kinoshita Tatsuya; Kawakami Yuko; Mittler Robert S; Kwon Byoung S; Ware Carl F; Croft Michael; Kawakami Toshiaki
Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor.
Blood 2005;106(13):4241-8.
2005: Benedict Chris A; Ware Carl F
RIGing a virus trap.
Nature medicine 2005;11(9):929-30.
2005: Cheung Timothy C; Humphreys Ian R; Potter Karen G; Norris Paula S; Shumway Heather M; Tran Bonnie R; Patterson Ginelle; Jean-Jacques Rochelle; Yoon Miri; Spear Patricia G; Murphy Kenneth M; Lurain Nell S; Benedict Chris A; Ware Carl F
Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(37):13218-23.
2005: Banks Theresa A; Rickert Sandra; Benedict Chris A; Ma Lisa; Ko Mira; Meier Joshua; Ha Won; Schneider Kirsten; Granger Steven W; Turovskaya Olga; Elewaut Dirk; Otero Dennis; French Anthony R; Henry Stanley C; Hamilton John D; Scheu Stefanie; Pfeffer Klaus; Ware Carl F
A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7217-25.
2005: Kabashima Kenji; Banks Theresa A; Ansel K Mark; Lu Theresa T; Ware Carl F; Cyster Jason G
Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells.
Immunity 2005;22(4):439-50.
2005: Cohavy Offer; Zhou Jaclyn; Ware Carl F; Targan Stephan R
LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):646-53.
2005: Sedy John R; Gavrieli Maya; Potter Karen G; Hurchla Michelle A; Lindsley R Coleman; Hildner Kai; Scheu Stefanie; Pfeffer Klaus; Ware Carl F; Murphy Theresa L; Murphy Kenneth M
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator.
Nature immunology 2005;6(1):90-8.
2005: Ware Carl F
Network communications: lymphotoxins, LIGHT, and TNF.
Annual review of immunology 2005;23():787-819.
2004: Schneider Kirsten; Potter Karen G; Ware Carl F
Lymphotoxin and LIGHT signaling pathways and target genes.
Immunological reviews 2004;202():49-66.
2004: Qian Youcun; Qin Jinzhong; Cui Grace; Naramura Mayumi; Snow E Charles; Ware Carl F; Fairchild Robert L; Omori Sidne A; Rickert Robert C; Scott Martin; Kotzin Brian L; Li Xiaoxia
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival.
Immunity 2004;21(4):575-87.
2004: Cohavy Offer; Zhou Jaclyn; Granger Steve W; Ware Carl F; Targan Stephan R
LIGHT expression by mucosal T cells may regulate IFN-gamma expression in the intestine.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):251-8.
2004: So Takanori; Salek-Ardakani Shahram; Nakano Hiroyasu; Ware Carl F; Croft Michael
TNF receptor-associated factor 5 limits the induction of Th2 immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4292-7.
2004: Benedict Chris A; Angulo Ana; Patterson Ginelle; Ha Sukwon; Huang Huang; Messerle Martin; Ware Carl F; Ghazal Peter
Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro.
Journal of virology 2004;78(2):741-50.
2003: Li Chenglong; Norris Paula S; Ni Chao-Zhou; Havert Marnie L; Chiong Elizabeth M; Tran Bonnie R; Cabezas Edelmira; Reed John C; Satterthwait Arnold C; Ware Carl F; Ely Kathryn R
Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.
The Journal of biological chemistry 2003;278(50):50523-9.
2003: Lo James C; Chin Robert K; Lee Youjin; Kang Hyung-Sik; Wang Yang; Weinstock Joel V; Banks Theresa; Ware Carl F; Franzoso Guido; Fu Yang-Xin
Differential regulation of CCL21 in lymphoid/nonlymphoid tissues for effectively attracting T cells to peripheral tissues.
The Journal of clinical investigation 2003;112(10):1495-505.
2003: Chin Robert K; Lo James C; Kim Oliver; Blink Sarah E; Christiansen Peter A; Peterson Pärt; Wang Yang; Ware Carl; Fu Yang-Xin
Lymphotoxin pathway directs thymic Aire expression.
Nature immunology 2003;4(11):1121-7.
2003: Gavin Amanda L; Aït-Azzouzene Djemel; Ware Carl F; Nemazee David
DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF.
The Journal of biological chemistry 2003;278(40):38220-8.
2003: Elewaut Dirk; Shaikh Raziya B; Hammond Kirsten J L; De Winter Hilde; Leishman Andrew J; Sidobre Stephane; Turovskaya Olga; Prigozy Theodore I; Ma Lisa; Banks Theresa A; Lo David; Ware Carl F; Cheroutre Hilde; Kronenberg Mitchell
NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells.
The Journal of experimental medicine 2003;197(12):1623-33.
2003: Ware Carl F
The TNF superfamily.
Cytokine & growth factor reviews 2003;14(3-4):181-4.
2003: Benedict Chris A; Banks Theresa A; Ware Carl F
Death and survival: viral regulation of TNF signaling pathways.
Current opinion in immunology 2003;15(1):59-65.
2002: Benedict Chris A; Norris Paula S; Ware Carl F
To kill or be killed: viral evasion of apoptosis.
Nature immunology 2002;3(11):1013-8.
2002: Dejardin Emmanuel; Droin Nathalie M; Delhase Mireille; Haas Elvira; Cao Yixue; Makris Constantin; Li Zhi-Wei; Karin Michael; Ware Carl F; Green Douglas R
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways.
Immunity 2002;17(4):525-35.
2002: Delhase Mireille; Ware Carl
The Cytokine Odyssey 2001, a joint meeting of the Society of Leukocyte Biology and the International Cytokine Society. 8-11 November 2001, Maui, Hawaii, USA.
Expert opinion on therapeutic targets 2002;6(1):115-21.
2001: Granger S W; Ware C F
Turning on LIGHT.
The Journal of clinical investigation 2001;108(12):1741-2.
2001: Shaikh R B; Santee S; Granger S W; Butrovich K; Cheung T; Kronenberg M; Cheroutre H; Ware C F
Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6330-7.
2001: Granger S W; Butrovich K D; Houshmand P; Edwards W R; Ware C F
Genomic characterization of LIGHT reveals linkage to an immune response locus on chromosome 19p13.3 and distinct isoforms generated by alternate splicing or proteolysis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5122-8.
2001: Benedict C A; Banks T A; Senderowicz L; Ko M; Britt W J; Angulo A; Ghazal P; Ware C F
Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente.
Immunity 2001;15(4):617-26.
2001: Benedict C A; Ware C F
Virus targeting of the tumor necrosis factor superfamily.
Virology 2001;289(1):1-5.
2001: Duffield J S; Ware C F; Ryffel B; Savill J
Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages.
The American journal of pathology 2001;159(4):1397-404.
2001: Ameloot P; Fiers W; De Bleser P; Ware C F; Vandenabeele P; Brouckaert P
Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants.
The Journal of biological chemistry 2001;276(40):37426-30.
2001: Yoshida H; Kawamoto H; Santee S M; Hashi H; Honda K; Nishikawa S; Ware C F; Katsura Y; Nishikawa S I
Expression of alpha(4)beta(7) integrin defines a distinct pathway of lymphoid progenitors committed to T cells, fetal intestinal lymphotoxin producer, NK, and dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2511-21.
2001: Zapata J M; Pawlowski K; Haas E; Ware C F; Godzik A; Reed J C
A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.
The Journal of biological chemistry 2001;276(26):24242-52.
2001: Zhu N; Ware C F; Lai M M
Hepatitis C virus core protein enhances FADD-mediated apoptosis and suppresses TRADD signaling of tumor necrosis factor receptor.
Virology 2001;283(2):178-87.
2001: Inagaki-Ohara K; Yada S; Takamura N; Reaves M; Yu X; Liu E; Rooney I; Nicholas S; Castro A; Ware C F; Green D R; Lin T
p53-dependent radiation-induced crypt intestinal epithelial cells apoptosis is mediated in part through TNF-TNFR1 system.
Oncogene 2001;20(7):812-8.
2001: Benedict C A; Norris P S; Prigozy T I; Bodmer J L; Mahr J A; Garnett C T; Martinon F; Tschopp J; Gooding L R; Ware C F
Three adenovirus E3 proteins cooperate to evade apoptosis by tumor necrosis factor-related apoptosis-inducing ligand receptor-1 and -2.
The Journal of biological chemistry 2001;276(5):3270-8.
2001: Rooney I A; Benedict C A; Norris P S; Ware C F
Methods of study of tumor necrosis factor-related ligands in apoptosis.
Methods in cell biology 2001;66():499-526.
2000: Ware C F
APRIL and BAFF connect autoimmunity and cancer.
The Journal of experimental medicine 2000;192(11):F35-8.
2000: Lama J; Ware C F
Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine LIGHT on activated T cells.
Journal of virology 2000;74(20):9396-402.
2000: Sarrias M R; Whitbeck J C; Rooney I; Ware C F; Eisenberg R J; Cohen G H; Lambris J D
The three HveA receptor ligands, gD, LT-alpha and LIGHT bind to distinct sites on HveA.
Molecular immunology 2000;37(11):665-73.
2000: Elewaut D; Brossay L; Santee S M; Naidenko O V; Burdin N; De Winter H; Matsuda J; Ware C F; Cheroutre H; Kronenberg M
Membrane lymphotoxin is required for the development of different subpopulations of NK T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):671-9.
2000: Rooney I A; Butrovich K D; Glass A A; Borboroglu S; Benedict C A; Whitbeck J C; Cohen G H; Eisenberg R J; Ware C F
The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells.
The Journal of biological chemistry 2000;275(19):14307-15.
2000: Force W R; Glass A A; Benedict C A; Cheung T C; Lama J; Ware C F
Discrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kappaB pathways.
The Journal of biological chemistry 2000;275(15):11121-9.
2000: Caulin C; Ware C F; Magin T M; Oshima R G
Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis.
The Journal of cell biology 2000;149(1):17-22.
2000: Lee B J; Santee S; Von Gesjen S; Ware C F; Sarawar S R
Lymphotoxin-alpha-deficient mice can clear a productive infection with murine gammaherpesvirus 68 but fail to develop splenomegaly or lymphocytosis.
Journal of virology 2000;74(6):2786-92.
2000: Rooney I; Butrovich K; Ware C F
Expression of lymphotoxins and their receptor-Fc fusion proteins by baculovirus.
Methods in enzymology 2000;322():345-63.
2000: Lai M M; Ware C F
Hepatitis C virus core protein: possible roles in viral pathogenesis.
Current topics in microbiology and immunology 2000;242():117-34.
1999: Lurain N S; Kapell K S; Huang D D; Short J A; Paintsil J; Winkfield E; Benedict C A; Ware C F; Bremer J W
Human cytomegalovirus UL144 open reading frame: sequence hypervariability in low-passage clinical isolates.
Journal of virology 1999;73(12):10040-50.
1999: Nakano H; Sakon S; Koseki H; Takemori T; Tada K; Matsumoto M; Munechika E; Sakai T; Shirasawa T; Akiba H; Kobata T; Santee S M; Ware C F; Rennert P D; Taniguchi M; Yagita H; Okumura K
Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9803-8.
1999: Sarrias M R; Whitbeck J C; Rooney I; Spruce L; Kay B K; Montgomery R I; Spear P G; Ware C F; Eisenberg R J; Cohen G H; Lambris J D
Inhibition of herpes simplex virus gD and lymphotoxin-alpha binding to HveA by peptide antagonists.
Journal of virology 1999;73(7):5681-7.
1999: Benedict C A; Butrovich K D; Lurain N S; Corbeil J; Rooney I; Schneider P; Tschopp J; Ware C F
Cutting edge: a novel viral TNF receptor superfamily member in virulent strains of human cytomegalovirus.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):6967-70.
1999: Gramaglia I; Mauri D N; Miner K T; Ware C F; Croft M
Lymphotoxin alphabeta is expressed on recently activated naive and Th1-like CD4 cells but is down-regulated by IL-4 during Th2 differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1333-8.
1998: Devergne O; Cahir McFarland E D; Mosialos G; Izumi K M; Ware C F; Kieff E
Role of the TRAF binding site and NF-kappaB activation in Epstein-Barr virus latent membrane protein 1-induced cell gene expression.
Journal of virology 1998;72(10):7900-8.
1998: Murphy M; Walter B N; Pike-Nobile L; Fanger N A; Guyre P M; Browning J L; Ware C F; Epstein L B
Expression of the lymphotoxin beta receptor on follicular stromal cells in human lymphoid tissues.
Cell death and differentiation 1998;5(6):497-505.
1998: Akiba H; Nakano H; Nishinaka S; Shindo M; Kobata T; Atsuta M; Morimoto C; Ware C F; Malinin N L; Wallach D; Yagita H; Okumura K
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.
The Journal of biological chemistry 1998;273(21):13353-8.
1998: Zhu N; Khoshnan A; Schneider R; Matsumoto M; Dennert G; Ware C; Lai M M
Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis.
Journal of virology 1998;72(5):3691-7.
1998: Mauri D N; Ebner R; Montgomery R I; Kochel K D; Cheung T C; Yu G L; Ruben S; Murphy M; Eisenberg R J; Cohen G H; Spear P G; Ware C F
LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator.
Immunity 1998;8(1):21-30.
1997: Force W R; Cheung T C; Ware C F
Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-beta receptor.
The Journal of biological chemistry 1997;272(49):30835-40.
1997: Shisler J; Yang C; Walter B; Ware C F; Gooding L R
The adenovirus E3-10.4K/14.5K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis.
Journal of virology 1997;71(11):8299-306.
1997: Williams-Abbott L; Walter B N; Cheung T C; Goh C R; Porter A G; Ware C F
The lymphotoxin-alpha (LTalpha) subunit is essential for the assembly, but not for the receptor specificity, of the membrane-anchored LTalpha1beta2 heterotrimeric ligand.
The Journal of biological chemistry 1997;272(31):19451-6.
1997: Green D R; Ware C F
Fas-ligand: privilege and peril.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):5986-90.
1997: Nakano H; Shindo M; Yamada K; Yoshida M C; Santee S M; Ware C F; Jenkins N A; Gilbert D J; Yagita H; Copeland N C; Okumura K
Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.
Genomics 1997;42(1):26-32.
1997: VanArsdale T L; VanArsdale S L; Force W R; Walter B N; Mosialos G; Kieff E; Reed J C; Ware C F
Lymphotoxin-beta receptor signaling complex: role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor kappaB.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2460-5.
1997: Ortaldo J R; Winkler-Pickett R T; Nagata S; Ware C F
Fas involvement in human NK cell apoptosis: lack of a requirement for CD16-mediated events.
Journal of leukocyte biology 1997;61(2):209-15.
1997: Matsumoto M; Hsieh T Y; Zhu N; VanArsdale T; Hwang S B; Jeng K S; Gorbalenya A E; Lo S Y; Ou J H; Ware C F; Lai M M
Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor.
Journal of virology 1997;71(2):1301-9.
1997: Yang Y; Liu Z H; Ware C F; Ashwell J D
A cysteine protease inhibitor prevents activation-induced T-cell apoptosis and death of peripheral blood cells from human immunodeficiency virus-infected individuals by inhibiting upregulation of Fas ligand.
Blood 1997;89(2):550-7.
1996: Brunner T; Yoo N J; LaFace D; Ware C F; Green D R
Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506.
International immunology 1996;8(7):1017-26.
1996: Nakano H; Oshima H; Chung W; Williams-Abbott L; Ware C F; Yagita H; Okumura K
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor.
The Journal of biological chemistry 1996;271(25):14661-4.
1996: Ware C F; VanArsdale S; VanArsdale T L
Apoptosis mediated by the TNF-related cytokine and receptor families.
Journal of cellular biochemistry 1996;60(1):47-55.
1995: Force W R; Walter B N; Hession C; Tizard R; Kozak C A; Browning J L; Ware C F
Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5280-8.
1995: Mason A T; McVicar D W; Smith C A; Young H A; Ware C F; Ortaldo J R
Regulation of NK cells through the 80-kDa TNFR (CD120b).
Journal of leukocyte biology 1995;58(2):249-55.
1995: Owen-Schaub L B; Angelo L S; Radinsky R; Ware C F; Gesner T G; Bartos D P
Soluble Fas/APO-1 in tumor cells: a potential regulator of apoptosis?
Cancer letters 1995;94(1):1-8.
1995: Yang Y; Mercep M; Ware C F; Ashwell J D
Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids.
The Journal of experimental medicine 1995;181(5):1673-82.
1995: Crowe P D; Walter B N; Mohler K M; Otten-Evans C; Black R A; Ware C F
A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.
The Journal of experimental medicine 1995;181(3):1205-10.
1995: Mosialos G; Birkenbach M; Yalamanchili R; VanArsdale T; Ware C; Kieff E
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family.
Cell 1995;80(3):389-99.
1995: Brunner T; Mogil R J; LaFace D; Yoo N J; Mahboubi A; Echeverri F; Martin S J; Force W R; Lynch D H; Ware C F
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.
Nature 1995;373(6513):441-4.
1995: Ware C F; VanArsdale T L; Crowe P D; Browning J L
The ligands and receptors of the lymphotoxin system.
Current topics in microbiology and immunology 1995;198():175-218.
1994: VanArsdale T L; Ware C F
TNF receptor signal transduction. Ligand-dependent stimulation of a serine protein kinase activity associated with (CD120a) TNFR60.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):3043-50.
1994: Crowe P D; VanArsdale T L; Walter B N; Ware C F; Hession C; Ehrenfels B; Browning J L; Din W S; Goodwin R G; Smith C A
A lymphotoxin-beta-specific receptor.
Science (New York, N.Y.) 1994;264(5159):707-10.
1994: Wang C S; Walling L L; Gu Y Q; Ware C F; Lord E M
Two classes of proteins and mRNAs in Lilium longiflorum L. indentified by human vitronectin probes.
Plant physiology 1994;104(2):711-7.
1994: Crowe P D; VanArsdale T L; Walter B N; Dahms K M; Ware C F
Production of lymphotoxin (LT alpha) and a soluble dimeric form of its receptor using the baculovirus expression system.
Journal of immunological methods 1994;168(1):79-89.
1993: Crowe P D; VanArsdale T L; Goodwin R G; Ware C F
Specific induction of 80-kDa tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylation.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):6882-90.
1993: Browning J L; Ngam-ek A; Lawton P; DeMarinis J; Tizard R; Chow E P; Hession C; O'Brine-Greco B; Foley S F; Ware C F
Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface.
Cell 1993;72(6):847-56.
1992: Ware C F; Crowe P D; Grayson M H; Androlewicz M J; Browning J L
Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(12):3881-8.
1992: Androlewicz M J; Browning J L; Ware C F
Lymphotoxin is expressed as a heteromeric complex with a distinct 33-kDa glycoprotein on the surface of an activated human T cell hybridoma.
The Journal of biological chemistry 1992;267(4):2542-7.
1991: Ware C F; Crowe P D; Vanarsdale T L; Andrews J L; Grayson M H; Jerzy R; Smith C A; Goodwin R G
Tumor necrosis factor (TNF) receptor expression in T lymphocytes. Differential regulation of the type I TNF receptor during activation of resting and effector T cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4229-38.
1991: Browning J L; Androlewicz M J; Ware C F
Lymphotoxin and an associated 33-kDa glycoprotein are expressed on the surface of an activated human T cell hybridoma.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(4):1230-7.
1991: Horton T M; Ranheim T S; Aquino L; Kusher D I; Saha S K; Ware C F; Wold W S; Gooding L R
Adenovirus E3 14.7K protein functions in the absence of other adenovirus proteins to protect transfected cells from tumor necrosis factor cytolysis.
Journal of virology 1991;65(5):2629-39.
1991: Lichtenstein A; Gera J F; Andrews J; Berenson J; Ware C F
Inhibitors of ADP-ribose polymerase decrease the resistance of HER2/neu-expressing cancer cells to the cytotoxic effects of tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(6):2052-8.
1990: Kusher D I; Ware C F; Gooding L R
Induction of the heat shock response protects cells from lysis by tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(9):2925-31.
1990: Brooks E G; Wirt D P; Goldblum R M; Vaidya S; Asuncion M T; Patterson J C; Ware C F; Klimpel G R
Double-negative (CD4- CD8-) T cells with an alpha/beta T cell receptor. Non-MHC-restricted cytolytic activity and lymphokine production.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4507-12.
1990: Andrews J S; Berger A E; Ware C F
Characterization of the receptor for tumor necrosis factor (TNF) and lymphotoxin (LT) on human T lymphocytes. TNF and LT differ in their receptor binding properties and the induction of MHC class I proteins on a human CD4+ T cell hybridoma.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(7):2582-91.
1990: LaCour E G; Grayson M H; Ware C F; Pope R M
Enhanced cytotoxicity in the rheumatoid joint.
Clinical immunology and immunopathology 1990;54(3):431-41.
1989: Rodgers K E; Haviland D L; Ware C F
Protection from O,O,S-trimethyl phosphorothioate-induced immune suppression.
Immunopharmacology 1989;17(3):131-40.
1989: Rodgers K E; Stern M L; Ware C F
Effects of subacute administration of O,S,S-trimethyl phosphorodithioate on cellular and humoral immune response systems.
Toxicology 1989;54(2):183-95.
1989: Coffman F D; Green L M; Godwin A; Ware C F
Cytotoxicity mediated by tumor necrosis factor in variant subclones of the ME-180 cervical carcinoma line: modulation by specific inhibitors of DNA topoisomerase II.
Journal of cellular biochemistry 1989;39(2):95-105.
1989: Coffman F D; Haviland D L; Green L M; Ware C F
Cytotoxicity by tumor necrosis factor is linked with the cell cycle but does not require DNA synthesis.
Growth factors (Chur, Switzerland) 1989;1(4):357-64.
1988: Rodgers K E; Leung N; Ware C F
Effects of acute administration of O,S,S-trimethyl phosphorodithioate on the generation of cellular and humoral immune responses following in vitro stimulation.
Toxicology 1988;51(2-3):241-53.
1988: Rodgers K E; Grayson M H; Ware C F
Inhibition of cytotoxic T lymphocyte and natural killer cell-mediated lysis by O,S,S,-trimethyl phosphorodithioate is at an early postrecognition step.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(2):564-70.
1988: Coffman F D; Green L M; Ware C F
The relationship of receptor occupancy to the kinetics of cell death mediated by tumor necrosis factor.
Lymphokine research 1988;7(4):371-83.
1987: Schlemmer A F; Ware C F; Keen N T
Purification and characterization of a pectin lyase produced by Pseudomonas fluorescens W51.
Journal of bacteriology 1987;169(10):4493-8.
1987: Fletcher W H; Shiu W W; Ishida T A; Haviland D L; Ware C F
Resistance to the cytolytic action of lymphotoxin and tumor necrosis factor coincides with the presence of gap junctions uniting target cells.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(3):956-62.
1987: Rodgers K E; Leung N; Ware C F; Imamura T
Effects of O,S,S-trimethyl phosphorodithioate on immune function.
Toxicology 1987;43(2):201-16.
1986: Green L M; Reade J L; Ware C F; Devlin P E; Liang C M; Devlin J J
Cytotoxic lymphokines produced by cloned human cytotoxic T lymphocytes. II. A novel CTL-produced cytotoxin that is antigenically distinct from tumor necrosis factor and alpha-lymphotoxin.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(11):3488-93.
1986: Donato N J; Ware C F; Byus C V
A rat monoclonal antibody which interacts with mammalian ornithine decarboxylase at an epitope involved in phosphorylation.
Biochimica et biophysica acta 1986;884(2):370-82.
1986: Yamamoto R S; Ware C F; Granger G A
The human LT system. XI. Identification of LT and "TNF-like" forms from stimulated natural killers, specific and nonspecific cytotoxic human T cells in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(6):1878-84.
1986: Ware C F; Green L M; Reade J; Stern M L; Berger A E
Human T cell hybridomas producing cytotoxic lymphokines: induction of lymphotoxin release and killer cell activity by anti-CD3 monoclonal antibody or lectins and phorbol ester.
Lymphokine research 1986;5(4):313-24.
1985: Ware C F; Donato N J; Dorshkind K
Human, rat or mouse hybridomas secrete high levels of monoclonal antibodies following transplantation into mice with severe combined immunodeficiency disease (SCID).
Journal of immunological methods 1985;85(2):353-61.
1985: Green L M; Stern M L; Haviland D L; Mills B J; Ware C F
Cytotoxic lymphokines produced by cloned human cytotoxic T lymphocytes. I. Cytotoxins produced by antigen-specific and natural killer-like CTL are dissimilar to classical lymphotoxins.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(6):4034-43.
1985: Ware C F; Reade J L
Functional interactions of LFA-1, T8 and alloantigen surface structures in T-cell mediated cytotoxicity.
Advances in experimental medicine and biology 1985;184():323-41.
1984: Ware C F; Reade J L; Der L C
A rat anti-mouse kappa chain specific monoclonal antibody, 187.1.10: purification, immunochemical properties and its utility as a general second-antibody reagent.
Journal of immunological methods 1984;74(1):93-104.
1984: Green L M; Reade J L; Ware C F
Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines.
Journal of immunological methods 1984;70(2):257-68.
1983: Ware C F; Krangel M S; Pious D; Burakoff S J; Strominger J L
Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(3):1312-7.
1983: Ware C F; Sanchez-Madrid F; Krensky A M; Burakoff S J; Strominger J L; Springer T A
Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(3):1182-8.
1983: Hemler M E; Ware C F; Strominger J L
Characterization of a novel differentiation antigen complex recognize by a monoclonal antibody (A-1A5): unique activation-specific molecular forms on stimulated T cells.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(1):334-40.
1981: Ware C F; Kolb W P
Assembly of the functional membrane attack complex of human complement: formation of disulfide-linked C9 dimers.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(10):6426-30.
1981: Ware C F; Wetsel R A; Kolb W P
Physicochemical characterization of fluid phase (SC5b-9) and membrane derived (MC5b-9) attack complexes of human complement purified by immunoadsorbent affinity chromatography or selective detergent extraction.
Molecular immunology 1981;18(6):521-31.

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