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Guri Tzivion

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Chemicals & Drugs

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Deborah T Leicht; Ajay Rana; Vitaly Balan; Agnieszka Bronisz; Alexander Kaplun; Jun Zhu; Guri Tzivion
MEK-1 activates C-Raf through a Ras-independent mechanism.
Gary P Brennan; Tobias Engel; Eva M Jimenez-Mateos; Ross C McKiernan; Guri Tzivion; David C Henshall
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo.
Velusamy Rangasamy; Gautam Sondarva; Guri Tzivion; Basabi Rana; Joanna C Bakowska; Subhasis Das; Anumantha Kanthasamy; Tae Ho Lee; Kun Ping Lu; James S Malter; Rajakishore Mishra; Ajay Rana
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function.

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All Publications

2013: Deborah T Leicht; Ajay Rana; Vitaly Balan; Agnieszka Bronisz; Alexander Kaplun; Jun Zhu; Guri Tzivion
MEK-1 activates C-Raf through a Ras-independent mechanism.
Biochimica et biophysica acta 2013;1833(5):976-86.
2013: Gary P Brennan; Tobias Engel; Eva M Jimenez-Mateos; Ross C McKiernan; Guri Tzivion; David C Henshall
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo.
PloS one 2013;8(1):e54491.
2012: Velusamy Rangasamy; Gautam Sondarva; Guri Tzivion; Basabi Rana; Joanna C Bakowska; Subhasis Das; Anumantha Kanthasamy; Tae Ho Lee; Kun Ping Lu; James S Malter; Rajakishore Mishra; Ajay Rana
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(21):8149-54.
2011: Guri Tzivion; Nissim Hay
PI3K-AKT-FoxO axis in cancer and aging.
Biochimica et biophysica acta 2011;1813(11):1925.
2011: Guri Tzivion; Melissa Dobson; Gopalakrishnan Ramakrishnan
FoxO transcription factors; Regulation by AKT and 14-3-3 proteins.
Biochimica et biophysica acta 2011;1813(11):1938-45.
2011: Melissa Dobson; Rafael Fridman; Ludmila Kaplun; Stephanie Ma; Gopalakrishnan Ramakrishnan; Vitaly Balan; Guri Tzivion
Bimodal regulation of FoxO3 by AKT and 14-3-3.
Biochimica et biophysica acta 2011;1813(8):1453-64.
2010: Seaho Kim; Wei Huang; Emilio P Mottillo; anjum sohail; Yoon-Ah Ham; M Katie Conley-Lacomb; Chong Jai Kim; Guri Tzivion; Hyeong-Reh Choi Kim; Shihua Wang; Yong Q Chen; Rafael Fridman
Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP.
Biochimica et biophysica acta 2010;1803(11):1287-97.
2008: Vitaly Balan; Gregory S Miller; Ludmila Kaplun; Karina Balan; Zhaozhong Chong; Faqi Li; Alexander Kaplun; Mark F A VanBerkum; Robert Arking; D Carl Freeman; Kenneth Maiese; Guri Tzivion
Life span extension and neuronal cell protection by Drosophila nicotinamidase.
The Journal of biological chemistry 2008;283(41):27810-9.
2007: Deborah T Leicht; Vitaly Balan; Alexander Kaplun; Vinita Singh-Gupta; Ludmila Kaplun; Melissa Dobson; Guri Tzivion
Raf kinases: function, regulation and role in human cancer.
Biochimica et biophysica acta 2007;1773(8):1196-212.
2007: Kara E Sawarynski; Alexander Kaplun; Guri Tzivion; George S Brush
Distinct activities of the related protein kinases Cdk1 and Ime2.
Biochimica et biophysica acta 2007;1773(3):450-6.
2006: Agnieszka Bronisz; Sudarshana Sharma; Rong Hu; Jakub Godlewski; Guri Tzivion; Kim C Mansky; Michael C Ostrowski
Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors.
Molecular biology of the cell 2006;17(9):3897-906.
2006: Guri Tzivion; Vinita Singh Gupta; Ludmila Kaplun; Vitaly Balan
14-3-3 proteins as potential oncogenes.
Seminars in cancer biology 2006;16(3):203-13.
2006: Vitaly Balan; Deborah T Leicht; Jun Zhu; Karina Balan; Alexander Kaplun; Vinita Singh-Gupta; Jun Qin; Hong Ruan; Michael J Comb; Guri Tzivion
Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase.
Molecular biology of the cell 2006;17(3):1141-53.
2005: Jun Zhu; Vitaly Balan; Agnieszka Bronisz; Karina Balan; Hengrui Sun; Deborah T Leicht; Zhijun Luo; Jun Qin; Joseph Avruch; Guri Tzivion
Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding.
Molecular biology of the cell 2005;16(10):4733-44.
2003: Ying H Shen; Jakub Godlewski; Agnieszka Bronisz; Jun Zhu; Michael J Comb; Joseph Avruch; Guri Tzivion
Significance of 14-3-3 self-dimerization for phosphorylation-dependent target binding.
Molecular biology of the cell 2003;14(11):4721-33.
2003: Ying H Shen; Jakub Godlewski; Jun Zhu; Pradeep Sathyanarayana; Virna D Leaner; Michael J Birrer; Ajay Rana; Guri Tzivion
Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.
The Journal of biological chemistry 2003;278(29):26715-21.
2002: Pradeep Sathyanarayana; Manoj K Barthwal; Chanakya N Kundu; Mary Ellen Lane; Andreas Bergmann; Guri Tzivion; Ajay Rana
Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3.
Molecular cell 2002;10(6):1527-33.
2002: Guri Tzivion; Joseph Avruch
14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation.
The Journal of biological chemistry 2002;277(5):3061-4.
2001: Guri Tzivion; Ying H Shen; Jun Zhu
14-3-3 proteins; bringing new definitions to scaffolding.
Oncogene 2001;20(44):6331-8.
2001: C M Cahill; Guri Tzivion; N Nasrin; S Ogg; J Dore; Gary Ruvkun; MC Alexander-Bridges
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways.
The Journal of biological chemistry 2001;276(16):13402-10.
2001: Joseph Avruch; Andrei Khokhlatchev; John M Kyriakis; Zhijun Luo; Guri Tzivion; D Vavvas; Xian-feng Zhang
Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade.
Recent progress in hormone research 2001;56():127-55.
2000: Cynthia Hayne; Guri Tzivion; Zhijun Luo
Raf-1/MEK/MAPK pathway is necessary for the G2/M transition induced by nocodazole.
The Journal of biological chemistry 2000;275(41):31876-82.
2000: Michele T Yip-Schneider; W Miao; A Lin; Darlene S Barnard; Guri Tzivion; Mark S Marshall
Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association.
The Biochemical journal 2000;351(Pt 1):151-9.
2000: Guri Tzivion; Z J Luo; Joseph Avruch
Calyculin A-induced vimentin phosphorylation sequesters 14-3-3 and displaces other 14-3-3 partners in vivo.
The Journal of biological chemistry 2000;275(38):29772-8.
1998: Guri Tzivion; Zhijun Luo; Joseph Avruch
A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity.
Nature 1998;394(6688):88-92.
1996: Z Luo; Guri Tzivion; P J Belshaw; D Vavvas; M Marshall; Joseph Avruch
Oligomerization activates c-Raf-1 through a Ras-dependent mechanism.
Nature 1996;383(6596):181-5.
1995: D Ish-Shalom; Guri Tzivion; Claus T Christoffersen; Birgitte Uraø; Pierre De Meyts; David Naor
Mitogenic potential of insulin on lymphoma cells lacking IGF-1 receptor.
Annals of the New York Academy of Sciences 1995;766():409-15.