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Jiri Zemlicka

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John D Williams; Jiri Zemlicka; Emma A Harden; Caroll B Hartline; Geraldine M Jefferson; Kathy A Keith; Atiyya R Khan; Norton P Peet; Mark N Prichard; Terry L Bowlin
Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides.
Chengwei Li; Mark Prichard; Debra C Quenelle; John C Drach; Jiri Zemlicka
Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir.
Brian G Gentry; Sara N Gentry; Trachette L Jackson; Jiri Zemlicka; John C Drach
Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase.

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2012: John D Williams; Jiri Zemlicka; Emma A Harden; Caroll B Hartline; Geraldine M Jefferson; Kathy A Keith; Atiyya R Khan; Norton P Peet; Mark N Prichard; Terry L Bowlin
Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides.
Bioorganic & medicinal chemistry 2012;20(12):3710-8.
2012: Chengwei Li; Mark Prichard; Debra C Quenelle; John C Drach; Jiri Zemlicka
Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir.
Bioorganic & medicinal chemistry 2012;20(8):2669-74.
2011: Brian G Gentry; Sara N Gentry; Trachette L Jackson; Jiri Zemlicka; John C Drach
Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase.
Biochemical pharmacology 2011;81(1):43-9.
2010: Brian G Gentry; Jeremy P Kamil; Donald M Coen; Jiri Zemlicka; John C Drach
Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir.
Antimicrobial agents and chemotherapy 2010;54(8):3093-8.
2009: Chengwei Li; Brian G Gentry; John C Drach; Jiri Zemlicka
Synthesis and enantioselectivity of cyclopropavir phosphates for cellular GMP kinase.
Nucleosides, nucleotides & nucleic acids 2009;28(9):795-808.
2009: Santosh B Mhaske; Bashar Ksebati; Mark Prichard; John C Drach; Jiri Zemlicka
Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity.
Bioorganic & medicinal chemistry 2009;17(11):3892-9.
2009: Shaoman Zhou; John C Drach; Mark Prichard; Jiri Zemlicka
(Z)- and (E)-2-(1,2-dihydroxyethyl)methylenecyclopropane analogues of 2'-deoxyadenosine and 2'-deoxyguanosine. Synthesis of all stereoisomers, absolute configuration, and antiviral activity.
Journal of medicinal chemistry 2009;52(10):3397-407.
2009: Zhimeng Wu; Shaoman Zhou; Jiri Zemlicka
Stereoselective approach to the Z-isomers of methylenecyclopropane analogues of nucleosides: a new synthesis of antiviral synguanol.
Nucleosides, nucleotides & nucleic acids 2009;28(3):165-74.
2009: Zhimeng Wu; John C Drach; Mark Prichard; Milka Yanachkova; Ivan Yanachkov; Terry L Bowlin; Jiri Zemlicka
L-valine ester of cyclopropavir: a new antiviral prodrug.
Antiviral chemistry & chemotherapy 2009;20(1):37-46.
2008: Parmjeet Randhawa; Jiri Zemlicka; Andreas Sauerbrei; Chris Meier; Karl Y Hostetler; James R Beadle; Noush Afarin Farasati; Yuchen Huang; Matthews Bradley
Anti-BK virus activity of nucleoside analogs.
Antimicrobial agents and chemotherapy 2008;52(4):1519-21.
2008: Chengwei Li; Mark Prichard; Brent E Korba; John C Drach; Jiri Zemlicka
Fluorinated methylenecyclopropane analogues of nucleosides. Synthesis and antiviral activity of (Z)- and (E)-9-{[(2-fluoromethyl-2-hydroxymethyl)-cyclopropylidene]methyl}adenine and -guanine.
Bioorganic & medicinal chemistry 2008;16(5):2148-55.
2007: Shaoman Zhou; Jiri Zemlicka
Synthesis of 2,2,3-tris(hydroxymethyl)methylenecyclopropane analogues of nucleosides.
Nucleosides, nucleotides & nucleic acids 2007;26(4):391-402.
2007: Shaoman Zhou; Jiri Zemlicka; Earl R Kern; John C Drach
Fluoroanalogues of anti-cytomegalovirus agent cyclopropavir: synthesis and antiviral activity of (E)- and (Z)-9-{[2,2-bis(hydroxymethyl)-3-fluorocyclopropylidene]methyl}-adenines and guanines.
Nucleosides, nucleotides & nucleic acids 2007;26(3):231-43.
2007: Chengwei Li; Jiri Zemlicka
Synthesis of "reversed" methylenecyclopropane analogues of antiviral phosphonates.
Nucleosides, nucleotides & nucleic acids 2007;26(1):111-20.
2006: Shaoman Zhou; Earl R Kern; Elizabeth Gullen; Yung-Chi Cheng; John C Drach; Sadahiro Tamiya; Hiroaki Mitsuya; Jiri Zemlicka
9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
Journal of medicinal chemistry 2006;49(20):6120-8.
2006: Xinrong Qin; Xinchao Chen; Kun Wang; Lisa Anne Polin ; Earl R Kern; John C Drach; Elizabeth Gullen; Yung-Chi Cheng; Jiri Zemlicka
Synthesis, antiviral, and antitumor activity of 2-substituted purine methylenecyclopropane analogues of nucleosides.
Bioorganic & medicinal chemistry 2006;14(4):1247-54.
2005: Earl R Kern; Nicole L Kushner; Caroll B Hartline; Stephanie L Williams-Aziz; Emma A Harden; Shaoman Zhou; Jiri Zemlicka; Mark Prichard
In vitro activity and mechanism of action of methylenecyclopropane analogs of nucleosides against herpesvirus replication.
Antimicrobial agents and chemotherapy 2005;49(3):1039-45.
2005: Zhaohua Yan; Earl R Kern; Elizabeth Gullen; Yung-Chi Cheng; John C Drach; Jiri Zemlicka
Nucleotides and pronucleotides of 2,2-bis(hydroxymethyl)methylenecyclopropane analogues of purine nucleosides: synthesis and antiviral activity.
Journal of medicinal chemistry 2005;48(1):91-9.
2005: Amalraj Ambrose; Jiri Zemlicka; Earl R Kern; John C Drach; Elizabeth Gullen; Yung-Chi Cheng
Phosphoralaninate pronucleotides of pyrimidine methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
Nucleosides, nucleotides & nucleic acids 2005;24(10-12):1763-74.
2004: Shaoman Zhou; Earl R Kern; Elizabeth Gullen; Yung-Chi Cheng; John C Drach; Shintaro Matsumi; Hiroaki Mitsuya; Jiri Zemlicka
(Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a new class of methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
Journal of medicinal chemistry 2004;47(27):6964-72.
2004: Earl R Kern; Deborah J Bidanset; Caroll B Hartline; Zhaohua Yan; Jiri Zemlicka; Debra C Quenelle
Oral activity of a methylenecyclopropane analog, cyclopropavir, in animal models for cytomegalovirus infections.
Antimicrobial agents and chemotherapy 2004;48(12):4745-53.
2004: Shaoman Zhou; Julie M Breitenbach; Katherine Z Borysko; John C Drach; Earl R Kern; Elizabeth Gullen; Yung-Chi Cheng; Jiri Zemlicka
Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides.
Journal of medicinal chemistry 2004;47(3):566-75.
2003: Nicole L Kushner; Stephanie L Williams; Caroll B Hartline; Emma A Harden; Deborah J Bidanset; Xinchao Chen; Jiri Zemlicka; Earl R Kern
Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.
Nucleosides, nucleotides & nucleic acids 2003;22(12):2105-19.
2003: Ruifang Wang; Shigeyoshi Harada; Hiroaki Mitsuya; Jiri Zemlicka
Inhibition of human immunodeficiency virus reverse transcriptase by synadenol triphosphate and its E-isomer.
Journal of medicinal chemistry 2003;46(22):4799-802.
2003: Ruifang Wang; Xinchao Chen; John C Drach; Earl R Kern; Jiri Zemlicka
Synthesis and biological activity of 2-aminopurine methylenecyclopropane analogues of nucleosides.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):813-5.
2003: Xinchao Chen; Earl R Kern; John C Drach; Elizabeth Gullen; Yung-Chi Cheng; Jiri Zemlicka
Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus.
Journal of medicinal chemistry 2003;46(8):1531-7.
2003: Ruifang Wang; Xinchao Chen; John C Drach; Earl R Kern; Jiri Zemlicka
Synthesis and biological activity of 2-aminopurine methylenecyclopropane analogues of nucleosides.
Nucleosides, nucleotides & nucleic acids 2003;22(2):135-44.
2002: Fausto Baldanti; Antonella Sarasini; John C Drach; Jiri Zemlicka; Giuseppe Gerna
Z-isomers of 2-hydroxymethylcyclopropylidenemethyl adenine (synadenol) and guanine (synguanol) are active against ganciclovir- and foscarnet-resistant human cytomegalovirus UL97 mutants.
Antiviral research 2002;56(3):273-8.
2002: Ruifang Wang; Thomas H Corbett; Yung-Chi Cheng; John C Drach; Earl R Kern; Hiroaki Mitsuya; Jiri Zemlicka
Tryptophanyl phosphoramidates as prodrugs of synadenol and its E-isomer: synthesis and biological activity.
Bioorganic & medicinal chemistry letters 2002;12(17):2467-70.
2002: Jiri Zemlicka
Lipophilic phosphoramidates as antiviral pronucleotides.
Biochimica et biophysica acta 2002;1587(2-3):276-86.
2002: Ruifang Wang; Earl R Kern; Jiri Zemlicka
Synthesis of methylenecyclobutane analogues of nucleosides with axial chirality and their phosphoralaninates: a new pronucleotide effective against Epstein-Barr virus.
Antiviral chemistry & chemotherapy 2002;13(4):251-62.
2002: Sharad Rawale; Lew M Hrihorczuk; Wei-Zen Wei; Jiri Zemlicka
Synthesis and biological activity of the prodrug of class I major histocompatibility peptide GILGFVFTL activated by beta-glucuronidase.
Journal of medicinal chemistry 2002;45(4):937-43.
2002: David Egron; Christian Périgaud; Gilles Gosselin; Anne-Marie Aubertin; Hiroyuki Gatanaga; Hiroaki Mitsuya; Jiri Zemlicka; Jean-Louis Imbach
Increase of the adenallene anti-HIV activity in cell culture using its bis(tBuSATE) phosphotriester derivative.
Bioorganic & medicinal chemistry letters 2002;12(2):265-6.
2002: Xinchao Chen; Jiri Zemlicka
Revision of absolute configuration of enantiomeric (methylenecyclopropyl)carbinols obtained from (R)-(-)- and (S)-(+)-epichlorohydrin and methylenetriphenylphosphorane. Implications for reaction mechanism and improved synthesis of antiviral methylenecyclopropane analogues of nucleosides.
The Journal of organic chemistry 2002;67(1):286-9.
2001: Ruifang Wang; Mohamad Ksebati; Thomas H Corbett; Earl R Kern; John C Drach; Jiri Zemlicka
Methylene-gem-difluorocyclopropane analogues of nucleosides: synthesis, cyclopropene-methylenecyclopropane rearrangement, and biological activity.
Journal of medicinal chemistry 2001;44(23):4019-22.
2001: Ruifang Wang; Mohamad Ksebati; John C Drach; Jiri Zemlicka
Synthesis and antiviral activity of methylenedifluorocyclopropane analogues of nucleosides.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):329-32.
2000: Jiri Zemlicka
Nucleosides, nucleotides and their biological applications--XIV International Roundtable. Recent Advances in Nucleosides Chemistry and Chemotherapy. 10-14 September 2000, San Francisco, CA, USA.
IDrugs : the investigational drugs journal 2000;3(12):1453-4.
2000: H P Guan; Mohamad Ksebati; Earl R Kern; Jiri Zemlicka
Approaches to unsaturated analogues of nucleosides comprising four- and six-membered rings.
The Journal of organic chemistry 2000;65(17):5177-84.
2000: Rachel J Rybak; Caroll B Hartline; YL Qiu; Jiri Zemlicka; Emma A Harden; G Marshall; J P Sommadossi; Earl R Kern
In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections.
Antimicrobial agents and chemotherapy 2000;44(6):1506-11.
2000: YL Qiu; F Geiser; T Kira; Elizabeth Gullen; Yung-Chi Cheng; Roger G Ptak; Julie M Breitenbach; John C Drach; Caroll B Hartline; Earl R Kern; Jiri Zemlicka
Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells.
Antiviral chemistry & chemotherapy 2000;11(3):191-202.
2000: H P Guan; Mohamad Ksebati; Yung-Chi Cheng; John C Drach; Earl R Kern; Jiri Zemlicka
Spiropentane mimics of nucleosides: analogues of 2'-deoxyadenosine and 2'-deoxyguanosine. Synthesis of all stereoisomers, isomeric assignment, and biological activity.
The Journal of organic chemistry 2000;65(5):1280-90.
2000: Jiri Zemlicka
Enantioselectivity of the antiviral effects of nucleoside analogues.
Pharmacology & therapeutics 2000;85(3):251-66.
2000: Y L Qui; Mohamad Ksebati; Jiri Zemlicka
Synthesis of (Z)- and (E)-9-[(2-hydroxyethylidene)cyclopropyl]adenine--new methylenecyclopropane analogues of adenosine and their substrate activity for adenosine deaminase.
Nucleosides, nucleotides & nucleic acids 2000;19(1-2):31-7.
1999: YL Qiu; Jiri Zemlicka
Synthesis of new nucleoside analogues comprising a geminal difluorocyclopropane moiety as potential antiviral/antitumor agents.
Nucleosides & nucleotides 1999;18(10):2285-300.
1999: Rachel J Rybak; Jiri Zemlicka; YL Qiu; Caroll B Hartline; Earl R Kern
Effective treatment of murine cytomegalovirus infections with methylenecyclopropane analogues of nucleosides.
Antiviral research 1999;43(3):175-88.
1999: Kazuhisa Yoshimura; R Feldman; EN Kodama; Mark F Kavlick; YL Qiu; Jiri Zemlicka; Hiroaki Mitsuya
In vitro induction of human immunodeficiency virus type 1 variants resistant to phosphoralaninate prodrugs of Z-methylenecyclopropane nucleoside analogues.
Antimicrobial agents and chemotherapy 1999;43(10):2479-83.
1999: YL Qiu; Roger G Ptak; Julie M Breitenbach; JS Lin; Yung-Chi Cheng; John C Drach; Earl R Kern; Jiri Zemlicka
Synthesis and antiviral activity of phosphoralaninate derivatives of methylenecyclopropane analogues of nucleosides.
Antiviral research 1999;43(1):37-53.
1999: H Uchida; EN Kodama; Kazuhisa Yoshimura; Y Maeda; Pope Kosalaraksa; Victor Maroun; YL Qiu; Jiri Zemlicka; Hiroaki Mitsuya
In vitro anti-human immunodeficiency virus activities of Z- and E-methylenecyclopropane nucleoside analogues and their phosphoro-L-alaninate diesters.
Antimicrobial agents and chemotherapy 1999;43(6):1487-90.
1999: YL Qiu; Andrew Hempel; Norman Camerman; Arthur Camerman; F Geiser; Roger G Ptak; Julie M Breitenbach; T Kira; L Li; Elizabeth Gullen; Yung-Chi Cheng; John C Drach; Jiri Zemlicka
Methylenecyclopropane analogues of nucleosides: synthesis, absolute configuration, and enantioselectivity of antiviral effect of (R)-(-)- and (S)-(+)-synadenol.
Nucleosides & nucleotides 1999;18(4-5):597-8.
1998: YL Qiu; Andrew Hempel; Norman Camerman; Arthur Camerman; F Geiser; Roger G Ptak; Julie M Breitenbach; T Kira; L Li; Elizabeth Gullen; Yung-Chi Cheng; John C Drach; Jiri Zemlicka
(R)-(-)- and (S)-(+)-Synadenol: synthesis, absolute configuration, and enantioselectivity of antiviral effect.
Journal of medicinal chemistry 1998;41(26):5257-64.
1998: YL Qiu; Roger G Ptak; Julie M Breitenbach; JS Lin; Yung-Chi Cheng; Earl R Kern; John C Drach; Jiri Zemlicka
(Z)- and (E)-2-(hydroxymethylcyclopropylidene)-methylpurines and pyrimidines as antiviral agents.
Antiviral chemistry & chemotherapy 1998;9(4):341-52.
1998: YL Qiu; Mohamad Ksebati; Roger G Ptak; B Y Fan; Julie M Breitenbach; JS Lin; Yung-Chi Cheng; Earl R Kern; John C Drach; Jiri Zemlicka
(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.
Journal of medicinal chemistry 1998;41(1):10-23.
1997: Y L Zhu; S Balakrishna Pai; SH Liu; K L Grove; B C Jones; C Simons; Jiri Zemlicka; Yung-Chi Cheng
Inhibition of replication of hepatitis B virus by cytallene in vitro.
Antimicrobial agents and chemotherapy 1997;41(8):1755-60.
1997: H Winter; Y Maeda; H Uchida; Hiroaki Mitsuya; Jiri Zemlicka
Phosphodiester amidates of unsaturated nucleoside analogues: synthesis and anti-HIV activity.
Journal of medicinal chemistry 1997;40(14):2191-5.
1996: H Winter; Y Maeda; Hiroaki Mitsuya; Jiri Zemlicka
Phosphodiester amidates of allenic nucleoside analogues: anti-HIV activity and possible mechanism of action.
Journal of medicinal chemistry 1996;39(17):3300-6.
1995: B C Jones; J V Silverton; C Simons; S Megati; H Nishimura; Y Maeda; Hiroaki Mitsuya; Jiri Zemlicka
Synthesis, absolute configuration, and enantioselectivity of antiretroviral effect of (R)-(-)- and (S)-(+)-cytallene. Lipase-catalyzed enantioselective acylations of (+/-)-N4-acylcytallenes.
Journal of medicinal chemistry 1995;38(8):1397-405.
1995: Z Q Xu; YL Qiu; S Chokekijchai; Hiroaki Mitsuya; Jiri Zemlicka
Unsaturated acyclic analogues of 2'-deoxyadenosine and thymidine containing fluorine: synthesis and biological activity.
Journal of medicinal chemistry 1995;38(6):875-82.
1994: David Kessel; Jiri Zemlicka
Accumulation and metabolism of adenallene by murine leukemia L1210 cells.
Archives of biochemistry and biophysics 1994;308(1):222-5.
1993: Jiri Zemlicka; M C Fernandez-Moyano; M Ariatti; G E Zurenko; J E Grady; J P Ballesta
Hybrids of antibiotics inhibiting protein synthesis. Synthesis and biological activity.
Journal of medicinal chemistry 1993;36(9):1239-44.
1992: S Megati; Z Goren; J V Silverton; J Orlina; H Nishimura; T Shirasaki; Hiroaki Mitsuya; Jiri Zemlicka
(R)-(-)- and (S)-(+)-adenallene: synthesis, absolute configuration, enantioselectivity of antiretroviral effect, and enzymic deamination.
Journal of medicinal chemistry 1992;35(22):4098-104.
1990: A Ben Cheikh; L E Craine; Jiri Zemlicka; M J Hegg
Synthesis of norbornanepentols: analogues of inositols.
Carbohydrate research 1990;199(1):19-30.
1988: S Hayashi; S Phadtare; Jiri Zemlicka; M Matsukura; Hiroaki Mitsuya; S Broder
Adenallene and cytallene: acyclic-nucleoside analogues that inhibit replication and cytopathic effect of human immunodeficiency virus in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):6127-31.
1987: S Phadtare; Jiri Zemlicka
Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
Journal of medicinal chemistry 1987;30(2):437-40.
1987: S Phadtare; Jiri Zemlicka
Allenic derivatives of nucleic acid components and their transformation products: a new class of biologically active nucleoside analogues.
Nucleic acids symposium series 1987;(18):25-8.
1985: P Bhuta; Jiri Zemlicka
2'(3')-O-L-Phenylalanyl derivatives of N2,5'-anhydroformycin and N4,5'-anhydroformycin: new substrates for ribosomal peptidyltransferase with a fixed anti and syn conformation of the base.
Biochimica et biophysica acta 1985;841(2):145-50.
1983: Jiri Zemlicka; A Bhuta; P Bhuta
Analogues of 2'(3')-O-L-phenylalanyladenosine as substrates and inhibitors of ribosomal peptidyltransferase.
Journal of medicinal chemistry 1983;26(2):167-74.
1982: Jiri Zemlicka; A Bhuta
Sparsophenicol: a new synthetic hybrid antibiotic inhibiting ribosomal peptide synthesis.
Journal of medicinal chemistry 1982;25(10):1123-5.
1982: A Bhuta; Jiri Zemlicka
Inhibition of the puromycin reaction with benzamidine and related compounds.
FEBS letters 1982;142(2):215-8.
1980: P Bhuta; H L Chung; J S Hwang; Jiri Zemlicka
Analogues of chloramphenicol: circular dichroism spectra, inhibition of ribosomal peptidyltransferase, and possible mechanism of action.
Journal of medicinal chemistry 1980;23(12):1299-305.
1980: M Murata; P Bhuta; J Owens; Jiri Zemlicka
Inhibition of ribosomal peptidyltransferase with 2'(3')-O-acetyl-2 inches(3 inches)-O-glycyl-1,2-di(adenosin-N6-yl)ethane and -1,4-di(adenosin-N6-yl)butane. Effect of alkyl chain length.
Journal of medicinal chemistry 1980;23(7):781-6.
1980: Jiri Zemlicka
Synthesis of dicytidylyl-(3'-5')-1,2-di(adenosin-N6-yl)ethane and dicytidylyl-(3'-5')-1,4-di(adenosin-N6-yl)butane: covalently joined terminals of two transfer ribonucleic acids and their behavior toward snake venom phosphodiesterase.
Biochemistry 1980;19(1):163-8.
1978: P Bhuta; Jiri Zemlicka; P Bhuta
Inhibition of ribosomal peptidyltransferase with cytidyl-3' leads to 5'-[2'(3')-O-L-phenylalanyl]-L-adenosine.
Biochemical and biophysical research communications 1978;83(2):414-20.
1978: C D Li; P Bhuta; Jiri Zemlicka
Aminoacyl derivatives of "bridged" nucleosides: chemical synthesis and substrate activity of 2'(3')-O-(N-acetyl)-L-leucyl-2''(3'')-O-L-phenylalanyl-(1,2-diadenosin-N6-yl)ethane, a spacer probe for ribosomal peptidyltransferase.
Biochemistry 1978;17(13):2537-45.
1978: Sam C Brooks; J Rozhin; B A Pack; L Horn; V C Godefroi; E R Locke; Jiri Zemlicka; D V Singh
Role of sulfate conjugation in estrogen metabolism and activity.
Journal of toxicology and environmental health 1978;4(2-3):283-300.
1977: J S Hwang; P Bhuta; Jiri Zemlicka
Chemical aminoacylation of transfer ribonucleic acid. The reaction of Escherichia coli tRNA with ethyl N-benzyloxycarbonylorthoglycinate.
Biochimica et biophysica acta 1977;479(2):143-51.
1977: J Rozhin; A Huo; Jiri Zemlicka; Sam C Brooks
Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible involvement of adenine-estrogen stacking.
The Journal of biological chemistry 1977;252(20):7214-20.
1977: P Bhuta; C d Li; Jiri Zemlicka
2'(3')-O-L-Aminoacyl derivatives of "bridged" adenine ribonucleosides as substrates for fibosomal peptidyltransferase.
Biochemical and biophysical research communications 1977;77(4):1237-44.
1977: C Li; Jiri Zemlicka
Simple models of nucleic acid interactions 2. Aminoacyl derivatives of "bridged" nucleosides: Synthesis of 2'(3')-O-L-phenylalanyl- and 2'(3')-O-L-leucyl-1,2-di(adenosin-N6-yl)ethane.
The Journal of organic chemistry 1977;42(4):706-11.
1977: Jiri Zemlicka; J Owens
Simple models of nucleic acid interactions. 1. Base--base interactions in 1,2-Di)adenosin-N6-yl)ethane and 1,4-Di(adenosin-N6-yl)butane.
The Journal of organic chemistry 1977;42(3):517-23.
1976: Jiri Zemlicka; M Murata
Some transformations of DL-phenylalanine ortho esters and N-benzyloxycarbonyl-L-phenylalaninal.
The Journal of organic chemistry 1976;41(20):3317-21.
1976: Jiri Zemlicka; J Owens
2'(3')-O-L-(O-methyl-3-phenyllactyl) adenosine. A potential analog of 2'(3')-O-aminoacyl ribonucleosides.
Biochimica et biophysica acta 1976;442(1):71-5.
1975: Jiri Zemlicka; S Chládek; D Ringer; K Quiggle
Substrate specificity of ribosomal peptidyltransferase. Effect of modification in the heterocyclic, carbohydrate and amino acid moiety of 2'(3')-O-L-phenylalanyladenosine.
Biochemistry 1975;14(24):5239-49.
1975: R Petz; L Viktora; Jiri Zemlicka; J Cabicar
[Long-term studies on the effect of a rotating magnetic field on experimental mice].
Vnitr̆ní lékar̆ství 1975;21(9):894-900.
1975: Jiri Zemlicka; Jerome P Horwitz
Factors influencing the H6 chemical shift in pyrimidine nucleosides.
Journal of the American Chemical Society 1975;97(14):4089-95.
1975: Jerome P Horwitz; J J McCormick; K D Philips; V M Maher; J R Otto; David Kessel; Jiri Zemlicka
In vitro biological evaluation of the R and S isomers of 1-(Tetrahydrofuran-2-yl)-5-fluorouracil.
Cancer research 1975;35(5):1301-4.
1974: S Chládek; Jiri Zemlicka
Aminoacyl derivatives of nucleosides, nucleotides, and polynucleotides. 18. Synthesis of 2'(3')-O-aminoacyl derivatives of dinucleoside phosphates.
The Journal of organic chemistry 1974;39(15):2187-93.
1973: S Chládek; D Ringer; Jiri Zemlicka
L-Phenylalanine esters of open-chain analog of adenosine as substrates for ribosomal peptidyl transferase.
Biochemistry 1973;12(25):5135-8.
1973: E D Philips; Jiri Zemlicka; Jerome P Horwitz
Unsaturated sugars. I. Decarboxylative elimination of methyl 2,3-di-O-benzyl-alpha-D-glucopyranosiduronic acid to methyl 2,3-di-O-benzyl-4-deoxy-beta-L-threo-pent-4-enopyranoside.
Carbohydrate research 1973;30(2):281-6.
1973: Jiri Zemlicka
A possible role of organic activators in the ribosome-catalyzed peptide and ester bond formation.
Journal of theoretical biology 1973;39(1):241-8.
1973: Jiri Zemlicka; J V Freisler; R Gasser; Jerome P Horwitz
Nucleosides. XVI. The synthesis of 2',3'-dideoxy-3',4'-didehydro nucleosides.
The Journal of organic chemistry 1973;38(5):990-9.
1972: Jiri Zemlicka; R Gasser; J V Freisler; Jerome P Horwitz
Nucleosides. XV. Decarboxylative elimination of 2'-deoxynucleoside uronic acids.
Journal of the American Chemical Society 1972;94(9):3213-8.
1971: Jiri Zemlicka; S Chládek
Aminoacyl derivatives of nucleosides, nucleotides, and polynucleotides. XVI. Effect of some anions on the reaction course of peptide synthesis with active esters.
Biochimica et biophysica acta 1971;246(3):487-92.
1971: Jiri Zemlicka; S Chladek
Synthesis of 2'(3')-O-glycyl derivatives of cytidylyl-(3'-5')-inosine and 2'-deoxycytidylyl-(3'-5')-adenosine.
Biochemistry 1971;10(9):1521-5.
1970: Jiri Zemlicka; S Chladek
Scientific censorship.
Nature 1970;228(5271):589.
1970: I Rychlík; J Cerná; S Chládek; P Pulkrábek; Jiri Zemlicka
Substrate specificity of ribosomal peptidyl transferase. The effect of the nature of the amino acid side chain on the acceptor activity of 2'(3')-O-aminoacyladenosines.
European journal of biochemistry / FEBS 1970;16(1):136-42.
1970: Jiri Zemlicka; R Gasser; Jerome P Horwitz
Nucleosides. XII. A synthesis of 3',4'-unsaturated pyrimidine nucleosides.
Journal of the American Chemical Society 1970;92(15):4744-5.
1970: J Cerná; I Rychlík; Jiri Zemlicka; S Chládek
Substrate specificity of ribosomal peptidyl transferase. II. 2'(3')-O-aminoacyl nucleosides as acceptors of the peptide chain in the fragment reaction.
Biochimica et biophysica acta 1970;204(1):203-9.
1970: J Cerná; S Chládek; I Rychlík; Jiri Zemlicka
2',3'-O-bis-L-aminoacyladenosines and 2'(3')-O-L-phenylalanyl-L-phenylalanyladenosine: new acceptor substrates for peptidyltransferase.
Biochimica et biophysica acta 1970;199(1):291-3.
1969: I Rychlík; J Cerná; S Chládek; Jiri Zemlicka; Z Haladová
Substrate specificity of ribosomal peptidyl transferase: 2'(3')-O-aminoacyl nucleosides as acceptors of the peptide chain on the amino acid site.
Journal of molecular biology 1969;43(1):13-24.
1969: S Chládek; Jiri Zemlicka; V Gut
5-chloro-8-hydroxyquinoline (chloroxine) esters of carboxylic acid--selective reagents for acylation of nucleoside and nucleotide aminoacyl derivatives.
Biochemical and biophysical research communications 1969;35(2):306-11.
1966: S Chládek; Jiri Zemlicka; F Sorm
Chemical synthesis of 2'(3')-O-aminoacylribo-oligonucleotides: the preparation of cytidylyl-(3'-5')-2'(3')-O-glycyladenosine.
Biochemical and biophysical research communications 1966;22(5):554-8.
1965: Jiri Zemlicka; S Chládek
Synthesis of 2'(3')-O-aminoacyl derivatives of ribonucleosides and ribonucleoside-5'-phosphates via orthoester intermediatives. The preparation of 2'(3')-O-glycyl derivatives of uridine, adenosine and adenosine-5'-phosphate.
Tetrahedron letters 1965;(34):3057-63.