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Anna Cabrelle

Research Profile

Chemicals & Drugs

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Mouse

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B-Cell Chronic Lymphocytic Leukemia

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Antonella Teramo; Livio Trentin; Valentina Trimarco; Elisa Ave; Elisa Boscaro; Anna Cabrelle; Monica Facco; Federica Frezzato; Cristina Gattazzo; Albana Lico; Veronica Martini; Francesca Passeri; Francesco Piazza; Gianpietro Semenzato; Giulia Tasca; Renato Zambello
Intrinsic and extrinsic mechanisms contribute to maintain the JAK/STAT pathway aberrantly activated in T-type large granular lymphocyte leukemia.
Stefano Ugel; Steffen Walter; Toni Weinschenk; Anna Cabrelle; Mariacristina Chioda; Giacomo Desantis; Susanna Mandruzzato; Jordi C Ochando; Elisa Peranzoni; Vincenzo Bronte
Immune tolerance to tumor antigens occurs in a specialized environment of the spleen.
Sabrina Manni; Laura Pavan; Fausto Adami; Elisa Ave; Alessandra Brancalion; Anna Cabrelle; Anna Colpo; Giovanni Di Maira; Carmela Gurrieri; Lorenzo A Pinna; Maria Rita Pitari; Maria Ruzzene; Gianpietro Semenzato; Pierfrancesco Tassone; Laura Quotti Tubi; Fortunato Zaffino; Renato Zambello; Francesco Piazza
Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.

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All Publications

2013: Antonella Teramo; Livio Trentin; Valentina Trimarco; Elisa Ave; Elisa Boscaro; Anna Cabrelle; Monica Facco; Federica Frezzato; Cristina Gattazzo; Albana Lico; Veronica Martini; Francesca Passeri; Francesco Piazza; Gianpietro Semenzato; Giulia Tasca; Renato Zambello
Intrinsic and extrinsic mechanisms contribute to maintain the JAK/STAT pathway aberrantly activated in T-type large granular lymphocyte leukemia.
Blood 2013;121(19):3843-54.
2012: Stefano Ugel; Steffen Walter; Toni Weinschenk; Anna Cabrelle; Mariacristina Chioda; Giacomo Desantis; Susanna Mandruzzato; Jordi C Ochando; Elisa Peranzoni; Vincenzo Bronte
Immune tolerance to tumor antigens occurs in a specialized environment of the spleen.
Cell reports 2012;2(3):628-39.
2012: Sabrina Manni; Laura Pavan; Fausto Adami; Elisa Ave; Alessandra Brancalion; Anna Cabrelle; Anna Colpo; Giovanni Di Maira; Carmela Gurrieri; Lorenzo A Pinna; Maria Rita Pitari; Maria Ruzzene; Gianpietro Semenzato; Pierfrancesco Tassone; Laura Quotti Tubi; Fortunato Zaffino; Renato Zambello; Francesco Piazza
Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(7):1888-900.
2012: Federica Frezzato; Cristina Gattazzo; Veronica Martini; Gianpietro Semenzato; Antonella Teramo; Elena Tibaldi; Elisa Ave; Anna Maria Brunati; Anna Cabrelle; Samuela Carraro; Monica Facco; Valentina Trimarco; Renato Zambello; Livio Trentin
HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen.
PloS one 2012;7(6):e39902.
2011: Sveva Bollini; Michela Pozzobon; Muriel Nobles; Johannes Riegler; Xuebin Dong; Martina Piccoli; Angela Chiavegato; Anthony N Price; Marco Ghionzoli; King K Cheung; Anna Cabrelle; Paul R O'Mahoney; Emanuele Cozzi; Saverio Sartore; Andrew Tinker; Mark F Lythgoe; Paolo De Coppi
In vitro and in vivo cardiomyogenic differentiation of amniotic fluid stem cells.
Stem cell reviews 2011;7(2):364-80.
2011: Gian Paolo Fadini; Mattia Albiero; Lisa Menegazzo; Elisa Boscaro; Saula Vigili de Kreutzenberg; Carlo Agostini; Anna Cabrelle; Gianni Binotto; Marcello Rattazzi; Elisa Bertacco; Roberta Bertorelle; Lorena Biasini; Monica Mion; Mario Plebani; Giulio Ceolotto; Annalisa Angelini; Chiara Castellani; Mirko Menegolo; Franco Grego; Stefanie Dimmeler; Florian Seeger; Andreas Zeiher; Antonio Tiengo; Angelo Avogaro
Widespread increase in myeloid calcifying cells contributes to ectopic vascular calcification in type 2 diabetes.
Circulation research 2011;108(9):1112-21.
2011: Monica Facco; Anna Cabrelle; Antonella Teramo; Valeria Olivieri; Marianna Gnoato; Sara Teolato; Elisa Ave; Cristina Gattazzo; Gian Paolo Fadini; Fiorella Calabrese; Gianpietro Semenzato; Carlo Agostini
Sarcoidosis is a Th1/Th17 multisystem disorder.
Thorax 2011;66(2):144-50.
2011: Elisabetta Zulato; Francesca Favaretto; Caterina Veronese; Stefano Campanaro; Jan D Marshall; Sara Romano; Anna Cabrelle; Gayle B Collin; Barbara Zavan; Anna S Belloni; Enrica Rampazzo; Jürgen K Naggert; Giovanni Abatangelo; Nicola Sicolo; Pietro Maffei; Gabriella Milan; Roberto Vettor
ALMS1-deficient fibroblasts over-express extra-cellular matrix components, display cell cycle delay and are resistant to apoptosis.
PloS one 2011;6(4):e19081.
2010: Cristina Gattazzo; Antonella Teramo; Marta Miorin; Elisa Scquizzato; Anna Cabrelle; Mirna Balsamo; Carlo Agostini; Elena Vendrame; Monica Facco; Maria Paola Albergoni; Livio Trentin; Massimo Vitale; Gianpietro Semenzato; Renato Zambello
Lack of expression of inhibitory KIR3DL1 receptor in patients with natural killer cell-type lymphoproliferative disease of granular lymphocytes.
Haematologica 2010;95(10):1722-9.
2010: Gian Paolo Fadini; Mattia Albiero; Elisa Boscaro; Lisa Menegazzo; Anna Cabrelle; Teodoro Piliego; Massimo Federici; Carlo Agostini; Angelo Avogaro
Rosuvastatin stimulates clonogenic potential and anti-inflammatory properties of endothelial progenitor cells.
Cell biology international 2010;34(7):709-15.
2010: Carmela Gurrieri; Francesco Piazza; Marianna Gnoato; Barbara Montini; Lucia Biasutto; Cristina Gattazzo; Enrico Brunetta; Anna Cabrelle; Francesco Cinetto; Raffaele Niero; Monica Facco; Spiridione Garbisa; Fiorella Calabrese; Gianpietro Semenzato; Carlo Agostini
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione (SB216763), a glycogen synthase kinase-3 inhibitor, displays therapeutic properties in a mouse model of pulmonary inflammation and fibrosis.
The Journal of pharmacology and experimental therapeutics 2010;332(3):785-94.
2010: Francesco Piazza; Sabrina Manni; Laura Quotti Tubi; Barbara Montini; Laura Pavan; Anna Colpo; Marianna Gnoato; Anna Cabrelle; Fausto Adami; Renato Zambello; Livio Trentin; Carmela Gurrieri; Gianpietro Semenzato
Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death.
BMC cancer 2010;10():526.
2009: Anna Cabrelle; Nilla Maschio; Silvia Carraro; F Frezzato; Gianni Binotto; C Gattazzo; Marta Miorin; Carlo Agostini; Renato Zambello; F Pandolfi; Gianpietro Semenzato; Livio Trentin
Apoptotic effect of cyclosporin a and dexamethasone in malignant cells of patients with B-chronic lymphocytic leukemia.
Journal of biological regulators and homeostatic agents 2009;23(4):239-50.
2009: Mauro Salvi; Dong Xu; Yingyu Chen; Anna Cabrelle; Stefania Sarno; Lorenzo A Pinna
Programmed cell death protein 5 (PDCD5) is phosphorylated by CK2 in vitro and in 293T cells.
Biochemical and biophysical research communications 2009;387(3):606-10.
2009: Antonella Baron; Mariangela Mancini; Elizabeth Caldwell; Anna Cabrelle; Paolo Bernardi; Francesco Pagano
Serenoa repens extract targets mitochondria and activates the intrinsic apoptotic pathway in human prostate cancer cells.
BJU international 2009;103(9):1275-83.
2008: Giorgia Martini; Anna Cabrelle; Fiorella Calabrese; Samuela Carraro; Elisa Scquizzato; Antonella Teramo; Monica Facco; Francesco Zulian; Carlo Agostini
CXCR6-CXCL16 interaction in the pathogenesis of Juvenile Idiopathic Arthritis.
Clinical immunology (Orlando, Fla.) 2008;129(2):268-76.
2008: Anna Cabrelle; Isabella Dell'Aica; Luca Melchiori; Samuela Carraro; Enrico Brunetta; Raffaele Niero; Elisa Scquizzato; Giulia D'Intino; Laura Calzà; Spiridione Garbisa; Carlo Agostini
Hyperforin down-regulates effector function of activated T lymphocytes and shows efficacy against Th1-triggered CNS inflammatory-demyelinating disease.
Journal of leukocyte biology 2008;83(1):212-9.
2007: Monica Facco; Ilenia Baesso; Marta Miorin; Michela Bortoli; Anna Cabrelle; Elisa Boscaro; Carmela Gurrieri; Livio Trentin; Renato Zambello; Fiorella Calabrese; Marco A Cassatella; Gianpietro Semenzato; Carlo Agostini
Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis.
Journal of leukocyte biology 2007;82(4):946-55.
2007: Livio Trentin; Marta Miorin; Monica Facco; Ilenia Baesso; Samuela Carraro; Anna Cabrelle; Nilla Maschio; Michela Bortoli; Gianni Binotto; Francesco Piazza; Fausto Adami; Renato Zambello; Carlo Agostini; Gianpietro Semenzato
Multiple myeloma plasma cells show different chemokine receptor profiles at sites of disease activity.
British journal of haematology 2007;138(5):594-602.
2007: Isabella Dell'Aica; Raffaele Niero; Francesco Piazza; Anna Cabrelle; Luigi Sartor; cristiano colalto; Enrico Brunetta; Girieca Lorusso; Roberto Benelli; Adriana Albini; Fiorella Calabrese; Carlo Agostini; Spiridione Garbisa
Hyperforin blocks neutrophil activation of matrix metalloproteinase-9, motility and recruitment, and restrains inflammation-triggered angiogenesis and lung fibrosis.
The Journal of pharmacology and experimental therapeutics 2007;321(2):492-500.
2007: Alessandra Polenghi; Fleur Bossi; Fabio Fischetti; Paolo Durigutto; Anna Cabrelle; Nicola Tamassia; Marco A Cassatella; Cesare Montecucco; Francesco Tedesco; Marina de Bernard
The neutrophil-activating protein of Helicobacter pylori crosses endothelia to promote neutrophil adhesion in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1312-20.
2006: Gian Paolo Fadini; Saverio Sartore; Marco Schiavon; Mattia Albiero; Ilenia Baesso; Anna Cabrelle; Carlo Agostini; Angelo Avogaro
Diabetes impairs progenitor cell mobilisation after hindlimb ischaemia-reperfusion injury in rats.
Diabetologia 2006;49(12):3075-84.
2006: Francesco Piazza; Maria Ruzzene; Carmela Gurrieri; Barbara Montini; Luca Bonanni; Gino Chioetto; Giovanni Di Maira; Francesca Barbon; Anna Cabrelle; Renato Zambello; Fausto Adami; Livio Trentin; Lorenzo A Pinna; Gianpietro Semenzato
Multiple myeloma cell survival relies on high activity of protein kinase CK2.
Blood 2006;108(5):1698-707.
2006: Eva Milanesi; Paola Costantini; Alberto Gambalunga; Raffaele Colonna; Valeria Petronilli; Anna Cabrelle; Gianpietro Semenzato; Andrea M Cesura; emmanuel pinard; Paolo Bernardi
The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative.
The Journal of biological chemistry 2006;281(15):10066-72.
2006: Amedeo Amedei; Andrea Cappon; Gaia Codolo; Anna Cabrelle; Alessandra Polenghi; Marisa Benagiano; Elisabetta Tasca; Annalisa Azzurri; Mario Milco D'Elios; Gianfranco Del Prete; Marina de Bernard
The neutrophil-activating protein of Helicobacter pylori promotes Th1 immune responses.
The Journal of clinical investigation 2006;116(4):1092-101.
2006: Paolo Sfriso; Francesca Oliviero; Fiorella Calabrese; Marta Miorin; Monica Facco; Antonella Contri; Anna Cabrelle; Ilenia Baesso; Franco Cozzi; Marilisa Andretta; Marco A Cassatella; Ugo Fiocco; Silvano Todesco; Yrjö T Konttinen; Leonardo Punzi; Carlo Agostini
Epithelial CXCR3-B regulates chemokines bioavailability in normal, but not in Sjogren's syndrome, salivary glands.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2581-9.
2005: Carlo Agostini; Anna Cabrelle; Fiorella Calabrese; Michela Bortoli; Elisa Scquizzato; Samuela Carraro; Marta Miorin; Bianca Beghè; Livio Trentin; Renato Zambello; Monica Facco; Gianpietro Semenzato
Role for CXCR6 and its ligand CXCL16 in the pathogenesis of T-cell alveolitis in sarcoidosis.
American journal of respiratory and critical care medicine 2005;172(10):1290-8.
2005: Sonia Minuzzo; Stefano Indraccolo; Valeria Tosello; Erich Piovan; Anna Cabrelle; Livio Trentin; Gianpietro Semenzato; Alberto Amadori
Heterogeneous intracellular expression of B-cell receptor components in B-cell chronic lymphocytic leukaemia (B-CLL) cells and effects of CD79b gene transfer on surface immunoglobulin levels in a B-CLL-derived cell line.
British journal of haematology 2005;130(6):878-89.
2005: Carlo Foresta; Andrea Lana; Anna Cabrelle; Marco Ferigo; Nicola Caretta; Andrea Garolla; G Palù; Alberto Ferlin
PDE-5 inhibitor, Vardenafil, increases circulating progenitor cells in humans.
International journal of impotence research 2005;17(4):377-80.
2005: Sonia Minuzzo; Stefano Indraccolo; Valeria Tosello; Erich Piovan; Anna Cabrelle; Livio Trentin; Gianpietro Semenzato; Alberto Amadori
CD40 activation of B-CLL cells is associated with augmented intracellular levels of CD79b and increased BCR expression in a subset of patients.
Leukemia 2005;19(6):1099-101.
2005: Monica Facco; Chiara Zilli; Marta Siviero; Andrea Ermolao; Giuseppe Travain; Ilenia Baesso; Sondra Bonamico; Anna Cabrelle; Marco Zaccaria; Carlo Agostini
Modulation of immune response by the acute and chronic exposure to high altitude.
Medicine and science in sports and exercise 2005;37(5):768-74.
2005: Carlo Foresta; Nicola Caretta; Andrea Lana; Anna Cabrelle; G Palù; Alberto Ferlin
Circulating endothelial progenitor cells in subjects with erectile dysfunction.
International journal of impotence research 2005;17(3):288-90.
2005: Antonella Contri; Anna Maria Brunati; Livio Trentin; Anna Cabrelle; Marta Miorin; Luca Cesaro; Lorenzo A Pinna; Renato Zambello; Gianpietro Semenzato; Arianna Donella-Deana
Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.
The Journal of clinical investigation 2005;115(2):369-78.
2005: Erich Piovan; Valeria Tosello; Stefano Indraccolo; Anna Cabrelle; Ilenia Baesso; Livio Trentin; Rita Zamarchi; Hirokazu Tamamura; Nobutaka Fujii; Gianpietro Semenzato; Luigi Chieco-Bianchi; Alberto Amadori
Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation.
Blood 2005;105(3):931-9.
2005: Georgia Martini; Francesco Zulian; Fiorella Calabrese; Michela Bortoli; Monica Facco; Anna Cabrelle; Marialuisa Valente; Franco Zacchello; Carlo Agostini
CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritis.
Arthritis research & therapy 2005;7(2):R241-9.
2005: Carlo Agostini; Fiorella Calabrese; Venerino Poletti; Guido Marcer; Monica Facco; Marta Miorin; Anna Cabrelle; Ilenia Baesso; Renato Zambello; Livio Trentin; Gianpietro Semenzato
CXCR3/CXCL10 interactions in the development of hypersensitivity pneumonitis.
Respiratory research 2005;6():20.
2004: Lodovica Vergani; Maura Floreani; Aaron Russell; Mara Ceccon; Eleonora Napoli; Anna Cabrelle; Lucia Valente; Federica Bragantini; Bertrand Leger; Federica Dabbeni-Sala
Antioxidant defences and homeostasis of reactive oxygen species in different human mitochondrial DNA-depleted cell lines.
European journal of biochemistry / FEBS 2004;271(18):3646-56.
2004: Livio Trentin; Anna Cabrelle; Monica Facco; Davide Carollo; Marta Miorin; Alicia Tosoni; Paola Pizzo; Gianni Binotto; Linda Nicolardi; Renato Zambello; Fausto Adami; Carlo Agostini; Gianpietro Semenzato
Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas.
Blood 2004;104(2):502-8.
2004: Renato Zambello; Anna Cabrelle; Livio Trentin; Carlo Agostini; Gianpietro Semenzato; Antonella Viola
The raft marker GM1 identifies functional subsets of granular lymphocytes in patients with CD3+ lymphoproliferative disease of granular lymphocytes.
Leukemia 2004;18(4):771-6.
2004: Luca Benetti; Arianna Calistri; Cristina Ulivieri; Anna Cabrelle; Cosima T Baldari; Giorgio Palù; Cristina Parolin
Inhibition of ShcA isoforms p46/p52Shc enhances HIV-1 replication in CD4+ T-lymphocytes.
Journal of cellular physiology 2004;199(1):40-6.
2003: Renato Zambello; Michela Falco; Mariella Della Chiesa; Livio Trentin; Davide Carollo; Roberta Castriconi; Giovanna Cannas; Simona Carlomagno; Anna Cabrelle; Thierry Lamy; Carlo Agostini; Alessandro Moretta; Gianpietro Semenzato; Massimo Vitale
Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes.
Blood 2003;102(5):1797-805.
2003: Renato Zambello; Livio Trentin; Monica Facco; Davide Carollo; Anna Cabrelle; Alicia Tosoni; Giovanna Cannas; Linda Nicolardi; Carlo Agostini; Gianpietro Semenzato
Upregulation of CXCR1 by proliferating cells in patients with lymphoproliferative disease of granular lymphocytes.
British journal of haematology 2003;120(5):765-73.
2000: Elisa Apolloni; Vincenzo Bronte; Alessandra Mazzoni; paolo serafini; Anna Cabrelle; David M Segal; H A Young; Paola Zanovello
Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):6723-30.
2000: Vincenzo Bronte; Elisa Apolloni; Anna Cabrelle; R Ronca; paolo serafini; P Zamboni; Nicholas P Restifo; Paola Zanovello
Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells.
Blood 2000;96(12):3838-46.
1999: Lucia Ometto; Marisa Zanchetta; Anna Cabrelle; Giovanni Esposito; M Mainardi; Luigi Chieco-Bianchi; Anita De Rossi
Restriction of HIV type 1 infection in macrophages heterozygous for a deletion in the CC-chemokine receptor 5 gene.
AIDS research and human retroviruses 1999;15(16):1441-52.
1999: Vincenzo Bronte; D B Chappell; Elisa Apolloni; Anna Cabrelle; M Wang; P Hwu; Nicholas P Restifo
Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):5728-37.
1998: Monica Dettin; Claudia Scarinci; Carlo Zanotto; Anna Cabrelle; Anita De Rossi; Carlo Di Bello
Design, synthesis and CD4 binding studies of a fluorescent analogue of a peptide that enhances HIV-1 infectivity.
The journal of peptide research : official journal of the American Peptide Society 1998;51(2):110-5.
1996: B Macino; A Zambon; Gabriella Milan; Anna Cabrelle; Maria Ruzzene; Antonio Rosato; S Mandruzzato; Luigi Quintieri; Paola Zanovello; D Collavo
CD45 regulates apoptosis induced by extracellular adenosine triphosphate and cytotoxic T lymphocytes.
Biochemical and biophysical research communications 1996;226(3):769-76.
1996: G Monastra; Anna Cabrelle; A Zambon; Antonio Rosato; B Macino; D Collavo; Paola Zanovello
Membrane form of TNF alpha induces both cell lysis and apoptosis in susceptible target cells.
Cellular immunology 1996;171(1):102-10.