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Hong-Qiang Heng

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Heng Henry H Q; Bremer Steven W; Stevens Joshua B; Ye Karen J; Liu Guo; Ye Christine J
Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective.
Heng Henry H Q
The genome-centric concept: resynthesis of evolutionary theory.
Ye Christine J; Stevens Joshua B; Liu Guo; Bremer Steven W; Jaiswal Aruna S; Ye Karen J; Lin Ming-Fong; Lawrenson Lesley; Lancaster Wayne D; Kurkinen Markku; Liao Joshua D; Gairola C Gary; Shekhar Malathy P V; Narayan Satya; Miller Fred R; Heng Henry H Q
Genome based cell population heterogeneity promotes tumorigenicity: the evolutionary mechanism of cancer.

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All Publications

2009: Heng Henry H Q; Bremer Steven W; Stevens Joshua B; Ye Karen J; Liu Guo; Ye Christine J
Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective.
Journal of cellular physiology 2009;220(3):538-47.
2009: Heng Henry H Q
The genome-centric concept: resynthesis of evolutionary theory.
BioEssays : news and reviews in molecular, cellular and developmental biology 2009;31(5):512-25.
2009: Ye Christine J; Stevens Joshua B; Liu Guo; Bremer Steven W; Jaiswal Aruna S; Ye Karen J; Lin Ming-Fong; Lawrenson Lesley; Lancaster Wayne D; Kurkinen Markku; Liao Joshua D; Gairola C Gary; Shekhar Malathy P V; Narayan Satya; Miller Fred R; Heng Henry H Q
Genome based cell population heterogeneity promotes tumorigenicity: the evolutionary mechanism of cancer.
Journal of cellular physiology 2009;219(2):288-300.
2009: Espino Paula S; Pritchard Susan; Heng Henry H Q; Davie James R
Genomic instability and histone H3 phosphorylation induction by the Ras-mitogen activated protein kinase pathway in pancreatic cancer cells.
International journal of cancer. Journal international du cancer 2009;124(3):562-7.
2008: Heng Henry H Q
The conflict between complex systems and reductionism.
JAMA : the journal of the American Medical Association 2008;300(13):1580-1.
2008: Whittington Paula J; Piechocki Marie P; Heng Henry H; Jacob Jennifer B; Jones Richard F; Back Jessica B; Wei Wei-Zen
DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies.
Cancer research 2008;68(18):7502-11.
2008: Gong Lijie; Yao Fayi; Hockman Kristin; Heng Henry H; Morton Gregory J; Takeda Kiyoshi; Akira Shizuo; Low Malcolm J; Rubinstein Marcelo; MacKenzie Robert G
Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.
Endocrinology 2008;149(7):3346-54.
2008: Heng Henry H Q
The gene-centric concept: a new liability?
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(2):196-7.
2008: Heng Henry H Q; Stevens Joshua B; Lawrenson Lesley; Liu Guo; Ye Karen J; Bremer Steven W; Ye Christine J
Patterns of genome dynamics and cancer evolution.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2008;30(6):513-4.
2007: Stevens Joshua B; Liu Guo; Bremer Steven W; Ye Karen J; Xu Wenxin; Xu Jing; Sun Yi; Wu Gen Sheng; Savasan Sureyya; Krawetz Stephen A; Ye Christine J; Heng Henry H Q
Mitotic cell death by chromosome fragmentation.
Cancer research 2007;67(16):7686-94.
2007: Heng Henry H Q
Cancer genome sequencing: the challenges ahead.
BioEssays : news and reviews in molecular, cellular and developmental biology 2007;29(8):783-94.
2007: Heng Henry H Q
Elimination of altered karyotypes by sexual reproduction preserves species identity.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2007;50(5):517-24.
2007: Tait Larry R; Pauley Robert J; Santner Steven J; Heppner Gloria H; Heng Henry H; Rak Janusz W; Miller Fred R
Dynamic stromal-epithelial interactions during progression of MCF10DCIS.com xenografts.
International journal of cancer. Journal international du cancer 2007;120(10):2127-34.
2007: Ye C J; Liu G; Bremer S W; Heng H H Q
The dynamics of cancer chromosomes and genomes.
Cytogenetic and genome research 2007;118(2-4):237-46.
2006: Heng Henry H Q; Stevens Joshua B; Liu Gou; Bremer Steven W; Ye Karen J; Reddy Prem-Veer; Wu Gen Sheng; Wang Y Alan; Tainsky Michael A; Ye Christine J
Stochastic cancer progression driven by non-clonal chromosome aberrations.
Journal of cellular physiology 2006;208(2):461-72.
2006: Heng Henry H Q; Bremer Steven W; Stevens Joshua; Ye Karen J; Miller Fred; Liu Gou; Ye Christine J
Cancer progression by non-clonal chromosome aberrations.
Journal of cellular biochemistry 2006;98(6):1424-35.
2006: Heng Henry H Q; Liu Guo; Bremer Steven; Ye Karen J; Stevens Joshua; Ye Christine J
Clonal and non-clonal chromosome aberrations and genome variation and aberration.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2006;49(3):195-204.
2006: DiPierdomenico Julia; Ying Hao; Lin Feng; Heng Henry H Q
A mathematical model relating chromosome aberrations to cancer progression.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():2028-31.
2006: Ye C J; Stevens J B; Liu G; Ye K J; Yang F; Bremer S W; Heng H H Q
Combined multicolor-FISH and immunostaining.
Cytogenetic and genome research 2006;114(3-4):227-34.
2005: Woodward Karen J; Cundall Maria; Sperle Karen; Sistermans Erik A; Ross Mark; Howell Gareth; Gribble Susan M; Burford Deborah C; Carter Nigel P; Hobson Donald L; Garbern James Y; Kamholz John; Heng Henry; Hodes M E; Malcolm Sue; Hobson Grace M
Heterogeneous duplications in patients with Pelizaeus-Merzbacher disease suggest a mechanism of coupled homologous and nonhomologous recombination.
American journal of human genetics 2005;77(6):966-87.
2005: Roberts Paul C; Mottillo Emilio P; Baxa Andrea C; Heng Henry H Q; Doyon-Reale Nicole; Gregoire Lucie; Lancaster Wayne D; Rabah Raja; Schmelz Eva M
Sequential molecular and cellular events during neoplastic progression: a mouse syngeneic ovarian cancer model.
Neoplasia (New York, N.Y.) 2005;7(10):944-56.
2005: Shen Kate C; Heng Henry; Wang Yaolin; Lu Shu; Liu Guo; Deng Chu-Xia; Brooks S C; Wang Y Alan
ATM and p21 cooperate to suppress aneuploidy and subsequent tumor development.
Cancer research 2005;65(19):8747-53.
2005: Biliran Hector; Wang Yong; Banerjee Sanjeev; Xu Haiming; Heng Henry; Thakur Archana; Bollig Aliccia; Sarkar Fazlul H; Liao Joshua D
Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):6075-86.
2005: Heng Henry H Q; Windle Bradford; Tsui Lap-Chee
High-resolution FISH analysis.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2005;Chapter 4():Unit 4.5.
2004: Wu Xiaohua; Avni Dror; Chiba Takuya; Yan Feng; Zhao Qiping; Lin Yafang; Heng Henry; Livingston David
SV40 T antigen interacts with Nbs1 to disrupt DNA replication control.
Genes & development 2004;18(11):1305-16.
2004: Derjuga Anna; Gourley Tania S; Holm Teresa M; Heng Henry H Q; Shivdasani Ramesh A; Ahmed Rafi; Andrews Nancy C; Blank Volker
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.
Molecular and cellular biology 2004;24(8):3286-94.
2004: Heng Henry H Q; Goetze Sandra; Ye Christine J; Liu Guo; Stevens Joshua B; Bremer Steven W; Wykes Susan M; Bode Juergen; Krawetz Stephen A
Chromatin loops are selectively anchored using scaffold/matrix-attachment regions.
Journal of cell science 2004;117(Pt 7):999-1008.
2004: Kolas N K; Yuan L; Hoog C; Heng H H Q; Marcon E; Moens P B
Male mouse meiotic chromosome cores deficient in structural proteins SYCP3 and SYCP2 align by homology but fail to synapse and have possible impaired specificity of chromatin loop attachment.
Cytogenetic and genome research 2004;105(2-4):182-8.
2003: Yang Li V; Heng Henry H; Wan Junmei; Southwood Cherie M; Gow Alexander; Li Li
Alternative promoters and polyadenylation regulate tissue-specific expression of Hemogen isoforms during hematopoiesis and spermatogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;228(4):606-16.
2003: Takeuchi Tamotsu; Heng Henry H Q; Ye Christine J; Liang Sheng-Ben; Iwata Jun; Sonobe Hiroshi; Ohtsuki Yuji
Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.
The American journal of pathology 2003;163(4):1395-404.
2003: Heng H H Q; Ye C J; Yang F; Ebrahim S; Liu G; Bremer S W; Thomas C M; Ye J; Chen T J; Tuck-Muller C; Yu J W; Krawetz S A; Johnson A
Analysis of marker or complex chromosomal rearrangements present in pre- and post-natal karyotypes utilizing a combination of G-banding, spectral karyotyping and fluorescence in situ hybridization.
Clinical genetics 2003;63(5):358-67.
2003: Scherer Stephen W; Cheung Joseph; MacDonald Jeffrey R; Osborne Lucy R; Nakabayashi Kazuhiko; Herbrick Jo-Anne; Carson Andrew R; Parker-Katiraee Layla; Skaug Jennifer; Khaja Razi; Zhang Junjun; Hudek Alexander K; Li Martin; Haddad May; Duggan Gavin E; Fernandez Bridget A; Kanematsu Emiko; Gentles Simone; Christopoulos Constantine C; Choufani Sanaa; Kwasnicka Dorota; Zheng Xiangqun H; Lai Zhongwu; Nusskern Deborah; Zhang Qing; Gu Zhiping; Lu Fu; Zeesman Susan; Nowaczyk Malgorzata J; Teshima Ikuko; Chitayat David; Shuman Cheryl; Weksberg Rosanna; Zackai Elaine H; Grebe Theresa A; Cox Sarah R; Kirkpatrick Susan J; Rahman Nazneen; Friedman Jan M; Heng Henry H Q; Pelicci Pier Giuseppe; Lo-Coco Francesco; Belloni Elena; Shaffer Lisa G; Pober Barbara; Morton Cynthia C; Gusella James F; Bruns Gail A P; Korf Bruce R; Quade Bradley J; Ligon Azra H; Ferguson Heather; Higgins Anne W; Leach Natalia T; Herrick Steven R; Lemyre Emmanuelle; Farra Chantal G; Kim Hyung-Goo; Summers Anne M; Gripp Karen W; Roberts Wendy; Szatmari Peter; Winsor Elizabeth J T; Grzeschik Karl-Heinz; Teebi Ahmed; Minassian Berge A; Kere Juha; Armengol Lluis; Pujana Miguel Angel; Estivill Xavier; Wilson Michael D; Koop Ben F; Tosi Sabrina; Moore Gudrun E; Boright Andrew P; Zlotorynski Eitan; Kerem Batsheva; Kroisel Peter M; Petek Erwin; Oscier David G; Mould Sarah J; Döhner Hartmut; Döhner Konstanze; Rommens Johanna M; Vincent John B; Venter J Craig; Li Peter W; Mural Richard J; Adams Mark D; Tsui Lap-Chee
Human chromosome 7: DNA sequence and biology.
Science (New York, N.Y.) 2003;300(5620):767-72.
2003: Bode J; Goetze S; Heng H; Krawetz S A; Benham C
From DNA structure to gene expression: mediators of nuclear compartmentalization and dynamics.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2003;11(5):435-45.
2003: Cheung Joseph; Wilson Michael D; Zhang Junjun; Khaja Razi; MacDonald Jeffrey R; Heng Henry H Q; Koop Ben F; Scherer Stephen W
Recent segmental and gene duplications in the mouse genome.
Genome biology 2003;4(8):R47.
2002: Dong Shuo; Leung Keith K H; Pelling Anna L; Lee Patrick Y T; Tang Anna S P; Heng Henry H Q; Tsui Lap C; Tease Charles; Fisher Graham; Steel Karen P; Cheah Kathryn S E
Circling, deafness, and yellow coat displayed by yellow submarine (ysb) and light coat and circling (lcc) mice with mutations on chromosome 3.
Genomics 2002;79(6):777-84.
2002: Shekhar Malathy P V; Lyakhovich Alex; Visscher Daniel W; Heng Henry; Kondrat Noelle
Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation.
Cancer research 2002;62(7):2115-24.
2001: Schmid C; Heng H H; Rubin C; Ye C J; Krawetz S A
Sperm nuclear matrix association of the PRM1-->PRM2-->TNP2 domain is independent of Alu methylation.
Molecular human reproduction 2001;7(10):903-11.
2001: Heng H H; Liu G; Lu W; Bremer S; Ye C J; Hughes M; Moens P
Spectral karyotyping (SKY) of mouse meiotic chromosomes.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2001;44(2):293-8.
2001: Ding B C; Witt T L; Hukku B; Heng H; Zhang L; Matherly L H
Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.
Biochemical pharmacology 2001;61(6):665-75.
2001: Ye C J; Lu W; Liu G; Bremer S W; Wang Y A; Moens P; Hughes M; Krawetz S A; Heng H H
The combination of SKY and specific loci detection with FISH or immunostaining.
Cytogenetics and cell genetics 2001;93(3-4):195-202.
2001: Heng H H; Krawetz S A; Lu W; Bremer S; Liu G; Ye C J
Re-defining the chromatin loop domain.
Cytogenetics and cell genetics 2001;93(3-4):155-61.
2000: Lee D K; Lynch K R; Nguyen T; Im D S; Cheng R; Saldivia V R; Liu Y; Liu I S; Heng H H; Seeman P; George S R; O'Dowd B F; Marchese A
Cloning and characterization of additional members of the G protein-coupled receptor family.
Biochimica et biophysica acta 2000;1490(3):311-23.
2000: Liu G; Lu W; Bremer S; Hameister H; Schreiner B; Hughes M; Heng H H
Spectral karyotyping of mouse cell line WMP2.
Cytogenetics and cell genetics 2000;90(3-4):271-4.
2000: Heng H H
Released chromatin or DNA fiber preparations for high-resolution fiber FISH.
Methods in molecular biology (Clifton, N.J.) 2000;123():69-81.
2000: Heng H H; Spyropoulos B; Moens P B
DNA-protein in situ covisualization for chromosome analysis.
Methods in molecular biology (Clifton, N.J.) 2000;123():15-27.
1999: Wang A H; Bertos N R; Vezmar M; Pelletier N; Crosato M; Heng H H; Th'ng J; Han J; Yang X J
HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.
Molecular and cellular biology 1999;19(11):7816-27.
1999: Champagne N; Bertos N R; Pelletier N; Wang A H; Vezmar M; Yang Y; Heng H H; Yang X J
Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein.
The Journal of biological chemistry 1999;274(40):28528-36.
1999: Claudio J O; Liew C C; Ma J; Heng H H; Stewart A K; Hawley R G
Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13.
Genomics 1999;59(1):85-9.
1999: Omori F; Messner H A; Ye C; Gronda M V; O'Neill J P; Atkins H; Heng H H
Nontargeted stable integration of recombinant adeno-associated virus into human leukemia and lymphoma cell lines as evaluated by fluorescence in situ hybridization.
Human gene therapy 1999;10(4):537-43.
1999: Marchese A; Sawzdargo M; Nguyen T; Cheng R; Heng H H; Nowak T; Im D S; Lynch K R; George S R; O'dowd B F
Discovery of three novel orphan G-protein-coupled receptors.
Genomics 1999;56(1):12-21.
1999: Sawzdargo M; Nguyen T; Lee D K; Lynch K R; Cheng R; Heng H H; George S R; O'Dowd B F
Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.
Brain research. Molecular brain research 1999;64(2):193-8.
1999: Tarsounas M; Heng H H; Ye C J; Pearlman R E; Moens P B
Identification of the mouse beta'-COP Golgi component as a spermatocyte autoantigen in scleroderma and mapping of its gene Copb2 to mouse chromosome 9.
Cytogenetics and cell genetics 1999;87(3-4):201-4.
1998: Motoyama J; Heng H; Crackower M A; Takabatake T; Takeshima K; Tsui L C; Hui C
Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis.
Mechanisms of development 1998;78(1-2):81-4.
1998: Liu L; Wang L; Jia H P; Zhao C; Heng H H; Schutte B C; McCray P B; Ganz T
Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation.
Gene 1998;222(2):237-44.
1998: Crackower M A; Heng H H; Tsui L C
Assignment of mouse fibroblast growth factor 10 (Fgf10) gene to the telomeric region of chromosome 13.
Genomics 1998;53(2):247-8.
1998: Marchese A; Nguyen T; Malik P; Xu S; Cheng R; Xie Z; Heng H H; George S R; Kolakowski L F; O'Dowd B F
Cloning genes encoding receptors related to chemoattractant receptors.
Genomics 1998;50(2):281-6.
1998: Takeuchi T; Furihata M; Heng H H; Sonobe H; Ohtsuki Y
Chromosomal mapping and expression of the human B120 gene.
Gene 1998;213(1-2):189-93.
1998: Sam M; Wurst W; Klüppel M; Jin O; Heng H; Bernstein A
Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;212(2):304-17.
1998: Heng H H; Tsui L C
High resolution free chromatin/DNA fiber fluorescent in situ hybridization.
Journal of chromatography. A 1998;806(1):219-29.
1998: Pimenta A F; Tsui L C; Heng H H; Levitt P
Assignment of the gene encoding the limbic system-associated membrane protein (LAMP) to mouse chromosome 16B5 and human chromosome 3q13.2-q21.
Genomics 1998;49(3):472-4.
1998: Vadnal R; Heng H H; Parthasarathy L; Parthasarathy R
Human chromosomal localization of a gene for inositol monophosphatase by fluorescence in situ hybridization.
Neuroreport 1998;9(4):683-5.
1998: Heng H H; Wang A; Hu J
Mapping of the human HPRP3 and HPRP4 genes encoding U4/U6-associated splicing factors to chromosomes 1q21.1 and 9q31-q33.
Genomics 1998;48(2):273-5.
1998: Leclerc D; Wilson A; Dumas R; Gafuik C; Song D; Watkins D; Heng H H; Rommens J M; Scherer S W; Rosenblatt D S; Gravel R A
Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3059-64.
1998: Csóka A B; Frost G I; Heng H H; Scherer S W; Mohapatra G; Stern R;
The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus.
Genomics 1998;48(1):63-70.
1998: O'Dowd B F; Nguyen T; Marchese A; Cheng R; Lynch K R; Heng H H; Kolakowski L F; George S R
Discovery of three novel G-protein-coupled receptor genes.
Genomics 1998;47(2):310-3.
1998: Moens P B; Pearlman R E; Heng H H; Traut W
Chromosome cores and chromatin at meiotic prophase.
Current topics in developmental biology 1998;37():241-62.
1997: Rozmahel R; Heng H H; Duncan A M; Shi X M; Rommens J M; Tsui L C
Amplification of CFTR exon 9 sequences to multiple locations in the human genome.
Genomics 1997;45(3):554-61.
1997: Wang A; Forman-Kay J; Luo Y; Luo M; Chow Y H; Plumb J; Friesen J D; Tsui L C; Heng H H; Woolford J L; Hu J
Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome.
Human molecular genetics 1997;6(12):2117-26.
1997: Moens P B; Heddle J A; Spyropoulos B; Heng H H
Identical megabase transgenes on mouse chromosomes 3 and 4 do not promote ectopic pairing or synapsis at meiosis.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1997;40(5):770-3.
1997: Osborne L R; Herbrick J A; Greavette T; Heng H H; Tsui L C; Scherer S W
PMS2-related genes flank the rearrangement breakpoints associated with Williams syndrome and other diseases on human chromosome 7.
Genomics 1997;45(2):402-6.
1997: Okano K; Heng H; Trevisanato S; Tyers M; Varmuza S
Genomic organization and functional analysis of the murine protein phosphatase 1c gamma (Ppp1cc) gene.
Genomics 1997;45(1):211-5.
1997: Crackower M A; Heng H H; Shi X; Scherer S W; Tsui L C
Fluorescent in situ mapping of the murine deleted in split hand/split foot 1 (dss1) gene to chromosome 6.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(9):704.
1997: Moens P B; Chen D J; Shen Z; Kolas N; Tarsounas M; Heng H H; Spyropoulos B
Rad51 immunocytology in rat and mouse spermatocytes and oocytes.
Chromosoma 1997;106(4):207-15.
1997: Liu L; Zhao C; Heng H H; Ganz T
The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.
Genomics 1997;43(3):316-20.
1997: Snow B E; Heng H H; Shi X M; Zhou Y; Du K; Taub R; Tsui L C; McInnes R R
Expression analysis and chromosomal assignment of the human SFRS5/SRp40 gene.
Genomics 1997;43(2):165-70.
1997: Heng H H; Shi X M
From free chromatin analysis to high resolution fiber FISH.
Cell research 1997;7(1):119-24.
1997: Dong W F; Heng H H; Lowsky R; Xu Y; DeCoteau J F; Shi X M; Tsui L C; Minden M D
Cloning, expression, and chromosomal localization to 11p12-13 of a human LIM/HOMEOBOX gene, hLim-1.
DNA and cell biology 1997;16(6):671-8.
1997: O'Dowd B F; Nguyen T; Jung B P; Marchese A; Cheng R; Heng H H; Kolakowski L F; Lynch K R; George S R
Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes.
Gene 1997;187(1):75-81.
1997: Cohen D; Heng H H; Shi X M; McIntosh E M; Tsui L C; Pearlman R E
Assignment of the human dUTPase gene (DUT) to chromosome 15q15-q21. 1 by fluorescence in situ hybridization.
Genomics 1997;40(1):213-5.
1997: Crackower M A; Scherer S W; Heng H H; Tsui L C
Cloning of a DSS1 pseudogene (DSS1P1) and mapping to human chromosome band 5q14.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(2):159-60.
1997: Jung B P; Nguyen T; Kolakowski L F; Lynch K R; Heng H H; George S R; O'Dowd B F
Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1.
Biochemical and biophysical research communications 1997;230(1):69-72.
1997: Heng H H; Spyropoulos B; Moens P B
FISH technology in chromosome and genome research.
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(1):75-84.
1997: Mo R; Freer A M; Zinyk D L; Crackower M A; Michaud J; Heng H H; Chik K W; Shi X M; Tsui L C; Cheng S H; Joyner A L; Hui C
Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.
Development (Cambridge, England) 1997;124(1):113-23.
1996: Kolakowski L F; Jung B P; Nguyen T; Johnson M P; Lynch K R; Cheng R; Heng H H; George S R; O'Dowd B F
Characterization of a human gene related to genes encoding somatostatin receptors.
FEBS letters 1996;398(2-3):253-8.
1996: Tsukiyama-Kohara K; Vidal S M; Gingras A C; Glover T W; Hanash S M; Heng H; Sonenberg N
Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2.
Genomics 1996;38(3):353-63.
1996: Wagner J; Gordon L A; Heng H H; Tremblay M L; Olsen A S
Physical mapping of receptor type protein tyrosine phosphatase sigma (PTPRS) to human chromosome 19p13.3.
Genomics 1996;38(1):76-8.
1996: Belloni E; Muenke M; Roessler E; Traverso G; Siegel-Bartelt J; Frumkin A; Mitchell H F; Donis-Keller H; Helms C; Hing A V; Heng H H; Koop B; Martindale D; Rommens J M; Tsui L C; Scherer S W
Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly.
Nature genetics 1996;14(3):353-6.
1996: Yang B Z; Heng H H; Ding J H; Roe C R
The genes for the alpha and beta subunits of the mitochondrial trifunctional protein are both located in the same region of human chromosome 2p23.
Genomics 1996;37(1):141-3.
1996: Sam M; Wurst W; Forrester L; Vauti F; Heng H; Bernstein A
A novel family of repeat sequences in the mouse genome responsive to retinoic acid.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(10):741-8.
1996: O'Dowd B F; Nguyen T; Lynch K R; Kolakowski L F; Thompson M; Cheng R; Marchese A; Ng G; Heng H H; George S R
A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain.
FEBS letters 1996;394(3):325-9.
1996: Osborne L R; Martindale D; Scherer S W; Shi X M; Huizenga J; Heng H H; Costa T; Pober B; Lew L; Brinkman J; Rommens J; Koop B; Tsui L C
Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients.
Genomics 1996;36(2):328-36.
1996: Wang R; Cukerman E; Heng H H; Liew C C
Identification of a locus of zinc finger genes in human chromosome 19q13.1-q13.3 region by fluorescence in situ hybridization.
Somatic cell and molecular genetics 1996;22(3):245-8.
1996: Wang R; Cukerman E; Heng H H; Liew C C
Localization of three novel zinc finger genes to the centromeric region of human chromosome 10 by fluorescence in situ hybridization.
Somatic cell and molecular genetics 1996;22(3):241-4.
1996: Wang R; Cukerman E; Heng H H; Liew C C
Localization of a novel zinc finger gene to the human chromosome 7p11.2-p12 by fluorescence in situ hybridization.
Somatic cell and molecular genetics 1996;22(3):237-9.
1996: Wang R; Cukerman E; Heng H H; Liew C C
Localization of a novel zinc finger gene to human chromosome 7q22 region by fluorescence in situ hybridization.
Somatic cell and molecular genetics 1996;22(3):233-5.
1996: Heng H H; Chamberlain J W; Shi X M; Spyropoulos B; Tsui L C; Moens P B
Regulation of meiotic chromatin loop size by chromosomal position.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2795-800.
1996: Heiber M; Marchese A; Nguyen T; Heng H H; George S R; O'Dowd B F
A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3.
Genomics 1996;32(3):462-5.
1996: Wu H K; Heng H H; Siderovski D P; Dong W F; Okuno Y; Shi X M; Tsui L C; Minden M D
Identification of a human LIM-Hox gene, hLH-2, aberrantly expressed in chronic myelogenous leukaemia and located on 9q33-34.1.
Oncogene 1996;12(6):1205-12.
1996: Kim K K; Youn B S; Heng H H; Shi X M; Tsui L C; Lee Z H; Pickard R T; Kwon B S
Genomic organization and FISH mapping of human Pmel 17, the putative silver locus.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1996;9(1):42-8.
1996: Petronis A; Heng H H; Tatuch Y; Shi X M; Klempan T A; Tsui L C; Ashizawa T; Surh L C; Holden J J; Kennedy J L
Direct detection of expanded trinucleotide repeats using PCR and DNA hybridization techniques.
American journal of medical genetics 1996;67(1):85-91.
1996: Scherer S W; Duvoisin R M; Kuhn R; Heng H H; Belloni E; Tsui L C
Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.
Genomics 1996;31(2):230-3.
1996: Huang W Y; Heng H H; Liew C C
Assignment of the human GATA4 gene to 8p23.1-->p22 using fluorescence in situ hybridization analysis.
Cytogenetics and cell genetics 1996;72(2-3):217-8.
1996: Xie Y; Heng H H
FISH mapping of centromere protein C (CENPC) on human chromosome 4q31-->q21.
Cytogenetics and cell genetics 1996;74(3):192-3.
1996: Malaney S; Heng H H; Tsui L C; Shi X M; Robinson B H
Localization of the human gene encoding the 13.3-kDa subunit of mitochondrial complex III (UQCRB) to 8q22 by in situ hybridization.
Cytogenetics and cell genetics 1996;73(4):297-9.
1996: Zhang X L; Heng H H; Yang Y; Tsui L C; Parnes J R; Chamberlain J W
Chromosomal mapping of the second human CD8B gene locus.
Immunogenetics 1996;43(4):220-6.
1995: Nguyen T; Erb L; Weisman G A; Marchese A; Heng H H; Garrad R C; George S R; Turner J T; O'Dowd B F
Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene.
The Journal of biological chemistry 1995;270(52):30845-8.
1995: Marchese A; Heiber M; Nguyen T; Heng H H; Saldivia V R; Cheng R; Murphy P M; Tsui L C; Shi X; Gregor P
Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors.
Genomics 1995;29(2):335-44.
1995: Huang F; Shi L J; Heng H H; Fei J; Guo L H
Assignment of the human GABA transporter gene (GABATHG) locus to chromosome 3p24-p25.
Genomics 1995;29(1):302-4.
1995: Barron-Casella E A; Torres M A; Scherer S W; Heng H H; Tsui L C; Casella J F
Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families.
The Journal of biological chemistry 1995;270(37):21472-9.
1995: Wu H K; Heng H H; Shi X M; Forsdyke D R; Tsui L C; Mak T W; Minden M D; Siderovski D P
Differential expression of a basic helix-loop-helix phosphoprotein gene, G0S8, in acute leukemia and localization to human chromosome 1q31.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(8):1291-8.
1995: Fung Y W; Wang R X; Heng H H; Liew C C
Mapping of a human LIM protein (CLP) to human chromosome 11p15.1 by fluorescence in situ hybridization.
Genomics 1995;28(3):602-3.
1995: Charest A; Wagner J; Muise E S; Heng H H; Tremblay M L
Structure of the murine MPTP-PEST gene: genomic organization and chromosomal mapping.
Genomics 1995;28(3):501-7.
1995: O'Dowd B F; Scheideler M A; Nguyen T; Cheng R; Rasmussen J S; Marchese A; Zastawny R; Heng H H; Tsui L C; Shi X
The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.
Genomics 1995;28(1):84-91.
1995: Scherer S W; Heng H H; Robinson G W; Mahon K A; Evans J P; Tsui L C
Assignment of the human homolog of mouse Dlx3 to chromosome 17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in situ hybridization.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(4):310-1.
1995: Heiber M; Docherty J M; Shah G; Nguyen T; Cheng R; Heng H H; Marchese A; Tsui L C; Shi X; George S R
Isolation of three novel human genes encoding G protein-coupled receptors.
DNA and cell biology 1995;14(1):25-35.
1994: Heng H H; Tsui L C; Moens P B
Organization of heterologous DNA inserts on the mouse meiotic chromosome core.
Chromosoma 1994;103(6):401-7.
1994: Marchese A; Docherty J M; Nguyen T; Heiber M; Cheng R; Heng H H; Tsui L C; Shi X; George S R; O'Dowd B F
Cloning of human genes encoding novel G protein-coupled receptors.
Genomics 1994;23(3):609-18.
1994: Wu J; Salido E C; Yen P H; Mohandas T K; Heng H H; Tsui L C; Park J; Chapman V M; Shapiro L J
The murine Xe169 gene escapes X-inactivation like its human homologue.
Nature genetics 1994;7(4):491-6.
1994: Kunz J; Scherer S W; Klawitz I; Soder S; Du Y Z; Speich N; Kalff-Suske M; Heng H H; Tsui L C; Grzeschik K H
Regional localization of 725 human chromosome 7-specific yeast artificial chromosome clones.
Genomics 1994;22(2):439-48.
1994: Ing Y L; Leung I W; Heng H H; Tsui L C; Lassam N J
MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain.
Oncogene 1994;9(6):1745-50.
1994: Feng G S; Shen R; Heng H H; Tsui L C; Kazlauskas A; Pawson T
Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.
Oncogene 1994;9(6):1545-50.
1994: Heng H H; Xiao H; Shi X M; Greenblatt J; Tsui L C
Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome.
Human molecular genetics 1994;3(1):61-4.
1994: Marsden P A; Heng H H; Duff C L; Shi X M; Tsui L C; Hall A V
Localization of the human gene for inducible nitric oxide synthase (NOS2) to chromosome 17q11.2-q12.
Genomics 1994;19(1):183-5.
1994: Heng H H; Shi X M; Scherer S W; Andrulis I L; Tsui L C
Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/KO15.
Cytogenetics and cell genetics 1994;66(2):135-8.
1994: Heng H H; Tsui L C
FISH detection on DAPI-banded chromosomes.
Methods in molecular biology (Clifton, N.J.) 1994;33():35-49.
1994: Heng H H; Tsui L C
Free chromatin mapping by FISH.
Methods in molecular biology (Clifton, N.J.) 1994;33():109-22.
1994: Zhang X L; Lee K L; Heng H H; Tsui L C; Parnes J R; Shepherd N S; Chamberlain J W
Isolation of P1 bacteriophage clones containing large contiguous segments of the human and mouse loci for the T-cell coreceptor molecule CD8.
Genetic analysis, techniques and applications 1994;11(5-6):129-39.
1993: O'Dowd B F; Heiber M; Chan A; Heng H H; Tsui L C; Kennedy J L; Shi X; Petronis A; George S R; Nguyen T
A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11.
Gene 1993;136(1-2):355-60.
1993: Ali S T; Duncan A M; Schappert K; Heng H H; Tsui L C; Chow W; Robinson B H
Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13.
Genomics 1993;18(2):435-9.
1993: Heng H H; Xie B; Shi X M; Tsui L C; Mahuran D J
Refined mapping of the GM2 activator protein (GM2A) locus to 5q31.3-q33.1, distal to the spinal muscular atrophy locus.
Genomics 1993;18(2):429-31.
1993: Marsden P A; Heng H H; Scherer S W; Stewart R J; Hall A V; Shi X M; Tsui L C; Schappert K T
Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.
The Journal of biological chemistry 1993;268(23):17478-88.
1993: Heng H H; Tsui L C
Modes of DAPI banding and simultaneous in situ hybridization.
Chromosoma 1993;102(5):325-32.
1993: Heng H H; Shi X M; Tsui L C
Fluorescence in situ hybridization mapping of the cystic fibrosis transmembrane conductance regulator (CFTR) gene to 7q31.3.
Cytogenetics and cell genetics 1993;62(2-3):108-9.
1992: Heng H H; Squire J; Tsui L C
High-resolution mapping of mammalian genes by in situ hybridization to free chromatin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(20):9509-13.

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