FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

John Fazakerley

Research Profile

Living Beings

Disorders

Anatomy

Physiology

Virus Replication

Chemicals & Drugs

Concepts & Ideas

Virulence

Co-author Network

Publications

TOP 3
Gerald Barry; Pilar Alberdi; John Fazakerley; Alain Kohl; Esther Schnettler; Sabine Weisheit; Lesley Bell-Sakyi
Gene silencing in tick cell lines using small interfering or long double-stranded RNA.
Lesley Bell-Sakyi; Dennis A Bente; Alain Kohl; John Fazakerley
Tick cell lines for study of Crimean-Congo hemorrhagic fever virus and other arboviruses.
M Pilar Alberdi; Matthew J Dalby; John Fazakerley; Alain Kohl; Julio Rodriguez-Andres; Lesley Bell-Sakyi
Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of John Fazakerley (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Gerald Barry; Pilar Alberdi; John Fazakerley; Alain Kohl; Esther Schnettler; Sabine Weisheit; Lesley Bell-Sakyi
Gene silencing in tick cell lines using small interfering or long double-stranded RNA.
Experimental & applied acarology 2013;59(3):319-38.
2012: Lesley Bell-Sakyi; Dennis A Bente; Alain Kohl; John Fazakerley
Tick cell lines for study of Crimean-Congo hemorrhagic fever virus and other arboviruses.
Vector borne and zoonotic diseases (Larchmont, N.Y.) 2012;12(9):769-81.
2012: M Pilar Alberdi; Matthew J Dalby; John Fazakerley; Alain Kohl; Julio Rodriguez-Andres; Lesley Bell-Sakyi
Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines.
Ticks and tick-borne diseases 2012;3(3):137-46.
2012: Richard Howey; Nicholas Juleff; Nicholas J Savill; Bartlomiej Bankowski; Bryan Charleston; John Fazakerley; Debi Gibson; M E J Woolhouse
Modelling the within-host dynamics of the foot-and-mouth disease virus in cattle.
Epidemics 2012;4(2):93-103.
2012: Julio Rodriguez-Andres; Esther Schnettler; Michael R Strand; Margus Varjak; Gerald Barry; Markus H Beck; Margo E Chase-Topping; John Fazakerley; Mhairi C Ferguson; Rennos Fragkoudis; Andres Merits; Seema Rani; Alain Kohl
Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus.
PLoS pathogens 2012;8(11):e1002977.
2011: Ricky W C Siu; Rennos Fragkoudis; Peter Simmonds; Claire L Donald; Margo E Chase-Topping; Gerald Barry; Ghassem Attarzadeh-Yazdi; Julio Rodriguez-Andres; Anthony A Nash; Andres Merits; John Fazakerley; Alain Kohl
Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs.
Journal of virology 2011;85(6):2907-17.
2011: Anton G Gossner; James D Foster; John Fazakerley; Nora Hunter; John Hopkins
Gene expression analysis in distinct regions of the central nervous system during the development of SSBP/1 sheep scrapie.
Veterinary microbiology 2011;147(1-2):42-8.
2010: Gerald Barry; Rennos Fragkoudis; Mhairi C Ferguson; Aleksei Lulla; Andres Merits; Alain Kohl; John Fazakerley
Semliki forest virus-induced endoplasmic reticulum stress accelerates apoptotic death of mammalian cells.
Journal of virology 2010;84(14):7369-77.
2009: Rennos Fragkoudis; Ghassem Attarzadeh-Yazdi; Anthony A Nash; John Fazakerley; Alain Kohl
Advances in dissecting mosquito innate immune responses to arbovirus infection.
The Journal of general virology 2009;90(Pt 9):2061-72.
2009: Ghassem Attarzadeh-Yazdi; Rennos Fragkoudis; Yi Chi; Ricky W C Siu; Liane Ulper; Gerald Barry; Julio Rodriguez-Andres; Anthony A Nash; Michèle Bouloy; Andres Merits; John Fazakerley; Alain Kohl
Cell-to-cell spread of the RNA interference response suppresses Semliki Forest virus (SFV) infection of mosquito cell cultures and cannot be antagonized by SFV.
Journal of virology 2009;83(11):5735-48.
2009: Gerald Barry; Lucy Breakwell; Rennos Fragkoudis; Ghassem Attarzadeh-Yazdi; Julio Rodriguez-Andres; Alain Kohl; John Fazakerley
PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response.
The Journal of general virology 2009;90(Pt 6):1382-91.
2009: Rennos Fragkoudis; Nele Tamberg; Ricky Siu; Kaja Kiiver; Alain Kohl; Andres Merits; John Fazakerley
Neurons and oligodendrocytes in the mouse brain differ in their ability to replicate Semliki Forest virus.
Journal of neurovirology 2009;15(1):57-70.
2008: Rennos Fragkoudis; Y Chi; R W C Siu; G Barry; G Attarzadeh-Yazdi; Andres Merits; A A Nash; John Fazakerley; A Kohl
Semliki Forest virus strongly reduces mosquito host defence signaling.
Insect molecular biology 2008;17(6):647-56.
2008: Rennos Fragkoudis; Catherine M Ballany; Amanda Boyd; John Fazakerley
In Semliki Forest virus encephalitis, antibody rapidly clears infectious virus and is required to eliminate viral material from the brain, but is not required to generate lesions of demyelination.
The Journal of general virology 2008;89(Pt 10):2565-8.
2008: Kaja Kiiver; Ingrid Tagen; Eva Zusinaite; Nele Tamberg; John Fazakerley; Andres Merits
Properties of non-structural protein 1 of Semliki Forest virus and its interference with virus replication.
The Journal of general virology 2008;89(Pt 6):1457-66.
2008: N Johnson; K L Mansfield; D Hicks; A Nunez; Derek Healy; S M Brookes; Clive McKimmie; John Fazakerley; A R Fooks
Inflammatory responses in the nervous system of mice infected with a street isolate of rabies virus.
Developments in biologicals 2008;131():65-72.
2007: Alan Brown; A R Alejo Blanco; Gino Miele; S A Hawkins; J Hopkins; John Fazakerley; Jean Manson; Michael Clinton
Differential expression of erythroid genes in prion disease.
Biochemical and biophysical research communications 2007;364(2):366-71.
2007: Rennos Fragkoudis; Lucy Breakwell; Clive McKimmie; Amanda Boyd; Gerald Barry; Alain Kohl; Andres Merits; John Fazakerley
The type I interferon system protects mice from Semliki Forest virus by preventing widespread virus dissemination in extraneural tissues, but does not mediate the restricted replication of avirulent virus in central nervous system neurons.
The Journal of general virology 2007;88(Pt 12):3373-84.
2007: Lucy Breakwell; Pia Dosenovic; Gunilla B Karlsson Hedestam; Mauro D'Amato; Peter Liljeström; John Fazakerley; Gerald McInerney
Semliki Forest virus nonstructural protein 2 is involved in suppression of the type I interferon response.
Journal of virology 2007;81(16):8677-84.
2007: Nele Tamberg; Valeria Lulla; Rennos Fragkoudis; Aleksei Lulla; John Fazakerley; Andres Merits
Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus.
The Journal of general virology 2007;88(Pt 4):1225-30.
2006: Nicholas Johnson; Clive McKimmie; Karen L Mansfield; Philip R Wakeley; Sharon M Brookes; John Fazakerley; Anthony R Fooks
Lyssavirus infection activates interferon gene expression in the brain.
The Journal of general virology 2006;87(Pt 9):2663-7.
2006: John Fazakerley; C L Cotterill; G Lee; A Graham
Virus tropism, distribution, persistence and pathology in the corpus callosum of the Semliki Forest virus-infected mouse brain: a novel system to study virus-oligodendrocyte interactions.
Neuropathology and applied neurobiology 2006;32(4):397-409.
2006: Amanda Boyd; John Fazakerley; Anne Bridgen
Pathogenesis of Dugbe virus infection in wild-type and interferon-deficient mice.
The Journal of general virology 2006;87(Pt 7):2005-9.
2006: Clive McKimmie; Douglas Roy; Thorsten Forster; John Fazakerley
Innate immune response gene expression profiles of N9 microglia are pathogen-type specific.
Journal of neuroimmunology 2006;175(1-2):128-41.
2006: Audrey Graham; Robert Walker; Pauline Baird; Caroline N Hahn; John Fazakerley
CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(3):631-5.
2005: Clive McKimmie; John Fazakerley
In response to pathogens, glial cells dynamically and differentially regulate Toll-like receptor gene expression.
Journal of neuroimmunology 2005;169(1-2):116-25.
2005: Clive McKimmie; Nicholas Johnson; Anthony R Fooks; John Fazakerley
Viruses selectively upregulate Toll-like receptors in the central nervous system.
Biochemical and biophysical research communications 2005;336(3):925-33.
2005: Alan Brown; Selma Rebus; Clive McKimmie; Kevin Robertson; Alun Williams; John Fazakerley
Gene expression profiling of the preclinical scrapie-infected hippocampus.
Biochemical and biophysical research communications 2005;334(1):86-95.
2005: Anice C Lowen; Amanda Boyd; John Fazakerley; Richard M Elliott
Attenuation of bunyavirus replication by rearrangement of viral coding and noncoding sequences.
Journal of virology 2005;79(11):6940-6.
2004: Alan Brown; J Webb; Selma Rebus; Alun Williams; John Fazakerley
Identification of up-regulated genes by array analysis in scrapie-infected mouse brains.
Neuropathology and applied neurobiology 2004;30(5):555-67.
2004: F Davidson; C Lycett; Juraj Petrik; John Fazakerley
Investigation of frequency of active Borna disease virus infection in Scottish blood donors.
Vox sanguinis 2004;86(2):148-50.
2004: John Fazakerley
Semliki forest virus infection of laboratory mice: a model to study the pathogenesis of viral encephalitis.
Archives of virology. Supplementum 2004;(18):179-90.
2003: Alan Brown; Jeanette Webb; Selma Rebus; Robert Walker; Alun Williams; John Fazakerley
Inducible cytokine gene expression in the brain in the ME7/CV mouse model of scrapie is highly restricted, is at a strikingly low level relative to the degree of gliosis and occurs only late in disease.
The Journal of general virology 2003;84(Pt 9):2605-11.
2003: Hein Streitenfeld; Amanda Boyd; John Fazakerley; Anne Bridgen; Richard M Elliott; Friedemann Weber
Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs.
Journal of virology 2003;77(9):5507-11.
2003: John Fazakerley; Robert Walker
Virus demyelination.
Journal of neurovirology 2003;9(2):148-64.
2002: John Fazakerley
Pathogenesis of Semliki Forest virus encephalitis.
Journal of neurovirology 2002;8 Suppl 2():66-74.
2002: Friedemann Weber; Anne Bridgen; John Fazakerley; Hein Streitenfeld; Nina Kessler; Richard E Randall; Richard M Elliott
Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon.
Journal of virology 2002;76(16):7949-55.
2002: John Fazakerley; Amanda Boyd; Marja L Mikkola; Leevi Kääriäinen
A single amino acid change in the nuclear localization sequence of the nsP2 protein affects the neurovirulence of Semliki Forest virus.
Journal of virology 2002;76(1):392-6.
2001: Anne Bridgen; Friedemann Weber; John Fazakerley; Richard M Elliott
Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(2):664-9.
2001: John Fazakerley
Neurovirology and developmental neurobiology.
Advances in virus research 2001;56():73-124.
2001: John Fazakerley; Timothy E Allsopp
Programmed cell death in virus infections of the nervous system.
Current topics in microbiology and immunology 2001;253():95-119.
2000: L A Terry; James P Stewart; Anthony A Nash; John Fazakerley
Murine gammaherpesvirus-68 infection of and persistence in the central nervous system.
The Journal of general virology 2000;81(Pt 11):2635-43.
2000: Bahram Ebrahimi; Timothy E Allsopp; John Fazakerley; Gordon Harkiss
Phenotypic characterisation and infection of ovine microglial cells with Maedi-Visna virus.
Journal of neurovirology 2000;6(4):320-8.
2000: Timothy E Allsopp; John Fazakerley
Altruistic cell suicide and the specialized case of the virus-infected nervous system.
Trends in neurosciences 2000;23(7):284-90.
1999: MF Scallan; John Fazakerley
Aurothiolates enhance the replication of Semliki Forest virus in the CNS and the exocrine pancreas.
Journal of neurovirology 1999;5(4):392-400.
1998: K R Oliver; John Fazakerley
Transneuronal spread of Semliki Forest virus in the developing mouse olfactory system is determined by neuronal maturity.
Neuroscience 1998;82(3):867-77.
1998: Timothy E Allsopp; MF Scallan; A Williams; John Fazakerley
Virus infection induces neuronal apoptosis: A comparison with trophic factor withdrawal.
Cell death and differentiation 1998;5(1):50-9.
1997: K R Oliver; peter anthony brennan; John Fazakerley
Specific infection and destruction of dopaminergic neurons in the substantia nigra by Theiler's virus.
Journal of virology 1997;71(8):6179-82.
1997: MM Morris; H Dyson; David Baker; LS Harbige; John Fazakerley; Sandra Amor
Characterization of the cellular and cytokine response in the central nervous system following Semliki Forest virus infection.
Journal of neuroimmunology 1997;74(1-2):185-97.
1997: K R Oliver; MF Scallan; H Dyson; John Fazakerley
Susceptibility to a neurotropic virus and its changing distribution in the developing brain is a function of CNS maturity.
Journal of neurovirology 1997;3(1):38-48.
1997: MF Scallan; Timothy E Allsopp; John Fazakerley
bcl-2 acts early to restrict Semliki Forest virus replication and delays virus-induced programmed cell death.
Journal of virology 1997;71(2):1583-90.
1997: Helen O'Shea; J Crang; P Tonks; A A Nash; John Fazakerley
The PI capsid region of Theiler's virus controls replication in mouse glial cell cultures.
Archives of virology 1997;142(8):1521-35.
1996: J Pedro Simas; John Fazakerley
The course of disease and persistence of virus in the central nervous system varies between individual CBA mice infected with the BeAn strain of Theiler's murine encephalomyelitis virus.
The Journal of general virology 1996;77 ( Pt 11)():2701-11.
1996: Sandra Amor; MF Scallan; MM Morris; H Dyson; John Fazakerley
Role of immune responses in protection and pathogenesis during Semliki Forest virus encephalitis.
The Journal of general virology 1996;77 ( Pt 2 )():281-91.
1995: J Pedro Simas; H Dyson; John Fazakerley
The neurovirulent GDVII strain of Theiler's virus can replicate in glial cells.
Journal of virology 1995;69(9):5599-606.
1994: N P Sunil-Chandra; J Arno; John Fazakerley; Anthony A Nash
Lymphoproliferative disease in mice infected with murine gammaherpesvirus 68.
The American journal of pathology 1994;145(4):818-26.
1993: I Subak-Sharpe; H Dyson; John Fazakerley
In vivo depletion of CD8+ T cells prevents lesions of demyelination in Semliki Forest virus infection.
Journal of virology 1993;67(12):7629-33.
1993: John Fazakerley; S Pathak; MF Scallan; Sandra Amor; H Dyson
Replication of the A7(74) strain of Semliki Forest virus is restricted in neurons.
Virology 1993;195(2):627-37.
1993: John Fazakerley; Michael J Buchmeier
Pathogenesis of virus-induced demyelination.
Advances in virus research 1993;42():249-324.
1992: John Fazakerley; S E Parker; F Bloom; Michael J Buchmeier
The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system.
Virology 1992;187(1):178-88.
1991: John Fazakerley; P Southern; F Bloom; Michael J Buchmeier
High resolution in situ hybridization to determine the cellular distribution of lymphocytic choriomeningitis virus RNA in the tissues of persistently infected mice: relevance to arenavirus disease and mechanisms of viral persistence.
The Journal of general virology 1991;72 ( Pt 7)():1611-25.
1989: John Fazakerley; A M Ross
Computer analysis suggests a role for signal sequences in processing polyproteins of enveloped RNA viruses and as a mechanism of viral fusion.
Virus genes 1989;2(3):223-39.
1988: John Fazakerley; F Gonzalez-Scarano; J Strickler; Bernhard Dietzschold; F Karush; N Nathanson
Organization of the middle RNA segment of snowshoe hare Bunyavirus.
Virology 1988;167(2):422-32.
1988: John Fazakerley; Azadeh Khalili-Shirazi; H E Webb
Semliki Forest virus (A7[74]) infection of adult mice induces an immune-mediated demyelinating encephalomyelitis.
Annals of the New York Academy of Sciences 1988;540():672-3.
1987: A G Dalgleish; John Fazakerley; H E Webb
Do human T-lymphotrophic viruses (HTLVs) and other enveloped viruses induce autoimmunity in multiple sclerosis?
Neuropathology and applied neurobiology 1987;13(4):241-50.
1987: John Fazakerley; H E Webb
Cyclosporine enhances virally induced T-cell-mediated demyelination. The effect of cyclosporine on a demyelinating virus infection.
Journal of the neurological sciences 1987;78(1):35-50.
1987: John Fazakerley; H E Webb
Semliki Forest virus-induced, immune-mediated demyelination: adoptive transfer studies and viral persistence in nude mice.
The Journal of general virology 1987;68 ( Pt 2)():377-85.
1987: John Fazakerley; H E Webb
Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation.
British journal of experimental pathology 1987;68(1):101-13.
1986: John Fazakerley; H E Webb
Multiple sclerosis, viruses and glycolipids.
Nature 1986;321(6068):386.
1985: John Fazakerley; H E Webb
Cyclosporin, blood-brain barrier, and multiple sclerosis.
Lancet 1985;2(8460):889-90.
1984: H E Webb; John Fazakerley
Can viral envelope glycolipids produce auto-immunity, with reference to the CNS and multiple sclerosis?
Neuropathology and applied neurobiology 1984;10(1):1-10.
1983: John Fazakerley; Sandra Amor; H E Webb
Reconstitution of Semliki forest virus infected mice, induces immune mediated pathological changes in the CNS.
Clinical and experimental immunology 1983;52(1):115-20.
1982: D Beale; John Fazakerley; I R Smith
The limited fragmentation of porcine haemolytic immunoglobulin M. Evidence that haemolytic activity depends on the number of Fab arms that can attach to the erythrocyte surface.
Biochimica et biophysica acta 1982;704(1):156-62.
1981: D Beale; John Fazakerley
A comparison of the actions of trypsin and pepsin on porcine immunoglobulin M and their effects on biological activity.
Biochimica et biophysica acta 1981;670(2):230-5.
1980: D Beale; John Fazakerley
The action of pepsin on porcine immunoglobulin M and its effect on biological activity.
The Biochemical journal 1980;191(1):183-91.