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S Caccia

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Sandra Gemma; Beatrice Gorelli; Giovanna Guiso; Bhupendra P Joshi; Stefania Lamponi; Vittoria Moretti; Ettore Novellino; Silvia Parapini; Matthias Rottmann; Salvatore Sanna Coccone; simona saponara; Luisa Savini; Robert L Summers; Donatella Taramelli; Rowena E Martin; Nicoletta Basilico; Matteo Bernetti; Maria Cruz Bonache de Marcos; Simone Brogi; Reto Brun; S Caccia; Caterina Camodeca; Giuseppe Campiani; Stefania Butini
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
Stefania Butini; Roberta Budriesi; Michel Hamon; Elena Morelli; Sandra Gemma; Margherita Brindisi; Giuseppe Borrelli; Ettore Novellino; Isabella Fiorini; Pierfranco Ioan; Alberto Chiarini; Alfredo Cagnotto; Tiziana Mennini; Claudia Fracasso; S Caccia; Giuseppe Campiani
Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characterization.
Elena Morelli; Sandra Gemma; Roberta Budriesi; Giuseppe Campiani; Ettore Novellino; Caterina Fattorusso; Bruno Catalanotti; Salvatore Sanna Coccone; Sindu Ros; Giuseppe Borrelli; Marco Persico; Isabella Fiorini; Vito Nacci; Pierfranco Ioan; Alberto Chiarini; Michel Hamon; Alfredo Cagnotto; Tiziana Mennini; Claudia Fracasso; Milena Colovic; S Caccia; Stefania Butini
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.

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All Publications

2012: Sandra Gemma; Beatrice Gorelli; Giovanna Guiso; Bhupendra P Joshi; Stefania Lamponi; Vittoria Moretti; Ettore Novellino; Silvia Parapini; Matthias Rottmann; Salvatore Sanna Coccone; simona saponara; Luisa Savini; Robert L Summers; Donatella Taramelli; Rowena E Martin; Nicoletta Basilico; Matteo Bernetti; Maria Cruz Bonache de Marcos; Simone Brogi; Reto Brun; S Caccia; Caterina Camodeca; Giuseppe Campiani; Stefania Butini
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
Journal of medicinal chemistry 2012;55(15):6948-67.
2009: Stefania Butini; Roberta Budriesi; Michel Hamon; Elena Morelli; Sandra Gemma; Margherita Brindisi; Giuseppe Borrelli; Ettore Novellino; Isabella Fiorini; Pierfranco Ioan; Alberto Chiarini; Alfredo Cagnotto; Tiziana Mennini; Claudia Fracasso; S Caccia; Giuseppe Campiani
Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characterization.
Journal of medicinal chemistry 2009;52(21):6946-50.
2009: Elena Morelli; Sandra Gemma; Roberta Budriesi; Giuseppe Campiani; Ettore Novellino; Caterina Fattorusso; Bruno Catalanotti; Salvatore Sanna Coccone; Sindu Ros; Giuseppe Borrelli; Marco Persico; Isabella Fiorini; Vito Nacci; Pierfranco Ioan; Alberto Chiarini; Michel Hamon; Alfredo Cagnotto; Tiziana Mennini; Claudia Fracasso; Milena Colovic; S Caccia; Stefania Butini
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.
Journal of medicinal chemistry 2009;52(11):3548-62.
2009: Sandra Gemma; Giuseppe Campiani; Stefania Butini; Bhupendra P Joshi; Gagan Kukreja; Salvatore Sanna Coccone; Matteo Bernetti; Marco Persico; Vito Nacci; Isabella Fiorini; Ettore Novellino; Donatella Taramelli; Nicoletta Basilico; Silvia Parapini; Vanessa Yardley; Simon Croft; Sonja Keller-Maerki; Matthias Rottmann; Reto Brun; Massimo Coletta; Stefano Marini; Giovanna Guiso; S Caccia; Caterina Fattorusso
Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials.
Journal of medicinal chemistry 2009;52(2):502-13.
2001: giovanni maga; Anna Ramunno; Vito Nacci; Giada A Locatelli; Silvio Spadari; Isabella Fiorini; Fausto Baldanti; Stefania Paolucci; Maurizio Zavattoni; Alberto Bergamini; Bruno Galletti; S Muck; Ulrich Hubscher; G Giorgi; Giovanna Guiso; S Caccia; Giuseppe Campiani
The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors.
The Journal of biological chemistry 2001;276(48):44653-62.
2001: Giuseppe Campiani; Francesca Aiello; M Fabbrini; Elena Morelli; Anna Ramunno; S Armaroli; Vito Nacci; Antonio Garofalo; Giovanni Greco; Ettore Novellino; giovanni maga; Silvio Spadari; Alberto Bergamini; L Ventura; Barbara Bongiovanni; Marcella Capozzi; Francesca Bolacchi; Stefano Marini; Massimo Coletta; Giovanna Guiso; S Caccia
Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.
Journal of medicinal chemistry 2001;44(3):305-15.
2000: Giuseppe Campiani; M Fabbrini; Elena Morelli; Vito Nacci; Giovanni Greco; Ettore Novellino; giovanni maga; Silvio Spadari; Alberto Bergamini; E Faggioli; Ilaria Uccella; Francesca Bolacchi; Stefano Marini; Massimo Coletta; Claudia Fracasso; S Caccia
Non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis and biological evaluation of novel quinoxalinylethylpyridylthioureas as potent antiviral agents.
Antiviral chemistry & chemotherapy 2000;11(2):141-55.
1999: Giuseppe Campiani; Elena Morelli; M Fabbrini; Vito Nacci; Giovanni Greco; Ettore Novellino; Anna Ramunno; giovanni maga; Silvio Spadari; G Caliendo; Alberto Bergamini; E Faggioli; Ilaria Uccella; Francesca Bolacchi; Stefano Marini; Massimo Coletta; A Nacca; S Caccia
Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity.
Journal of medicinal chemistry 1999;42(21):4462-70.
1999: Giuseppe Campiani; Elena Morelli; Sandra Gemma; Vito Nacci; Stefania Butini; Michel Hamon; Ettore Novellino; Giovanni Greco; Alfredo Cagnotto; Mara Goegan; Luigi Cervo; F Dalla Valle; Claudia Fracasso; S Caccia; Tiziana Mennini
Pyrroloquinoxaline derivatives as high-affinity and selective 5-HT(3) receptor agonists: synthesis, further structure-activity relationships, and biological studies.
Journal of medicinal chemistry 1999;42(21):4362-79.
1997: Giuseppe Campiani; Andrea Cappelli; Vito Nacci; Maurizio Anzini; Salvatore Vomero; Michel Hamon; Alfredo Cagnotto; Claudia Fracasso; C Uboldi; S Caccia; S Consolo; Tiziana Mennini
Novel and highly potent 5-HT3 receptor agonists based on a pyrroloquinoxaline structure.
Journal of medicinal chemistry 1997;40(22):3670-8.