FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Axel Polack

Research Profile

Disorders

Burkitt's Lymphoma

Genes & Molecular Sequences

Genes, myc

Living Beings

Anatomy

Physiology

Chemicals & Drugs

Procedures

Cloning, Molecular

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Klaus Felix; Axel Polack; Walter Pretsch; Sharon H Jackson; Lionel Feigenbaum; Georg W Bornkamm; Siegfried Janz
Moderate hypermutability of a transgenic lacZ reporter gene in Myc-dependent inflammation-induced plasma cell tumors in mice.
Doriana Fruci; Gregoire Lauvau; Loredana Saveanu; Massimo Amicosante; Richard H Butler; Axel Polack; Ginhoux Florent; François Lemonnier; Hueseyin Firat; Peter van Endert
Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport.
Martin Staege; Steven P Lee; Teresa Frisan; Josef Mautner; Siegfried Scholz; Alexander Pajic; Alan B Rickinson; Maria Masucci; Axel Polack; Georg W Bornkamm
MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Axel Polack (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2004: Klaus Felix; Axel Polack; Walter Pretsch; Sharon H Jackson; Lionel Feigenbaum; Georg W Bornkamm; Siegfried Janz
Moderate hypermutability of a transgenic lacZ reporter gene in Myc-dependent inflammation-induced plasma cell tumors in mice.
Cancer research 2004;64(2):530-7.
2003: Doriana Fruci; Gregoire Lauvau; Loredana Saveanu; Massimo Amicosante; Richard H Butler; Axel Polack; Ginhoux Florent; François Lemonnier; Hueseyin Firat; Peter van Endert
Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):2977-84.
2002: Martin Staege; Steven P Lee; Teresa Frisan; Josef Mautner; Siegfried Scholz; Alexander Pajic; Alan B Rickinson; Maria Masucci; Axel Polack; Georg W Bornkamm
MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4550-5.
2002: Manfred Hergenhahn; Ubaldo Soto; Annette Weninger; Axel Polack; Chih-Hung Hsu; Ann-Lii Cheng; Frank Rösl
The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells.
Molecular carcinogenesis 2002;33(3):137-45.
2001: Alexander Pajic; Axel Polack; Martin Staege; D Spitkovsky; Barbara Baier; Georg W Bornkamm; Gerhard Laux
Elevated expression of c-myc in lymphoblastoid cells does not support an Epstein-Barr virus latency III-to-I switch.
The Journal of general virology 2001;82(Pt 12):3051-5.
2001: Alexander Pajic; Martin Staege; Diana Dudziak; Marino Schuhmacher; D Spitkovsky; Günther Eissner; Markus Brielmeier; Axel Polack; Georg W Bornkamm
Antagonistic effects of c-myc and Epstein-Barr virus latent genes on the phenotype of human B cells.
International journal of cancer. Journal international du cancer 2001;93(6):810-6.
2001: Marino Schuhmacher; Franz Kohlhuber; Michael Hölzel; C Kaiser; Helmut Burtscher; Michael Jarsch; Georg W Bornkamm; Gerhard Laux; Axel Polack; Ulrich H Weidle; Dirk Eick
The transcriptional program of a human B cell line in response to Myc.
Nucleic acids research 2001;29(2):397-406.
2000: Alexander L Kovalchuk; Chen-Feng Qi; Ted A Torrey; Lekidelu Taddesse-Heath; Lionel Feigenbaum; Sung Sup Park; Armin Gerbitz; G Klobeck; K Hoertnagel; Axel Polack; Georg W Bornkamm; Siegfried Janz; Herbert C Morse
Burkitt lymphoma in the mouse.
The Journal of experimental medicine 2000;192(8):1183-90.
2000: Alexander Pajic; D Spitkovsky; B Christoph; Bettina Kempkes; Marino Schuhmacher; Martin Staege; Markus Brielmeier; J Ellwart; Franz Kohlhuber; Georg W Bornkamm; Axel Polack; Dirk Eick
Cell cycle activation by c-myc in a burkitt lymphoma model cell line.
International journal of cancer. Journal international du cancer 2000;87(6):787-93.
2000: S Mücke; Andreas Draube; Axel Polack; M Pawlita; Nadia Massoudi; Andrea Staratschek-Jox; Heribert Bohlen; Georg W Bornkamm; Volker Diehl; Jürgen Wolf
Suppression of the tumorigenic growth of Burkitt's lymphoma cells in immunodeficient mice by cytokine gene transfer using EBV-derived episomal expression vectors.
International journal of cancer. Journal international du cancer 2000;86(3):301-6.
2000: Jean Feuillard; M Schuhmacher; S Kohanna; M Asso-Bonnet; F Ledeur; Raymonde Joubert-Caron; Philippe Bissières; Axel Polack; Georg W Bornkamm; Martine Raphaël
Inducible loss of NF-kappaB activity is associated with apoptosis and Bcl-2 down-regulation in Epstein-Barr virus-transformed B lymphocytes.
Blood 2000;95(6):2068-75.
2000: N E Wittekindt; K Hörtnagel; C Geltinger; Axel Polack
Activation of c-myc promoter P1 by immunoglobulin kappa gene enhancers in Burkitt lymphoma: functional characterization of the intron enhancer motifs kappaB, E box 1 and E box 2, and of the 3' enhancer motif PU.
Nucleic acids research 2000;28(3):800-8.
1999: Marino Schuhmacher; Martin Staege; Alexander Pajic; Axel Polack; Ulrich H Weidle; Georg W Bornkamm; Dirk Eick; Franz Kohlhuber
Control of cell growth by c-Myc in the absence of cell division.
Current biology : CB 1999;9(21):1255-8.
1999: Gerd Vogg; E Mattes; Axel Polack; Heinrich Sandermann
Tumor promoters in commercial indoor-plant cultivars of the Euphorbiaceae.
Environmental health perspectives 1999;107(9):753-6.
1999: W Shi; Ping Bu; J Liu; Axel Polack; Susan G Fisher; Liang Qiao
Human papillomavirus type 16 E7 DNA vaccine: mutation in the open reading frame of E7 enhances specific cytotoxic T-lymphocyte induction and antitumor activity.
Journal of virology 1999;73(9):7877-81.
1999: N Teramoto; Katja Pokrovskaja; Laszlo Szekely; Axel Polack; T Yoshino; T Akagi; George Klein
Expression of cyclin D2 and D3 in lymphoid lesions.
International journal of cancer. Journal international du cancer 1999;81(4):543-50.
1999: Raymonde Joubert-Caron; Jean Feuillard; S Kohanna; Florence Poirier; Jean-Pierre Le Caër; M Schuhmacher; Georg W Bornkamm; Axel Polack; Michel Caron; D Bladier; Martine Raphaël
A computer-assisted two-dimensional gel electrophoresis approach for studying the variations in protein expression related to an induced functional repression of NFkappaB in lymphoblastoid cell lines.
Electrophoresis 1999;20(4-5):1017-26.
1999: Armin Gerbitz; Josef Mautner; C Geltinger; K Hörtnagel; B Christoph; H Asenbauer; G Klobeck; Axel Polack; Georg W Bornkamm
Deregulation of the proto-oncogene c-myc through t(8;22) translocation in Burkitt's lymphoma.
Oncogene 1999;18(9):1745-53.
1999: Kou-Juey Wu; Carla Grandori; Mario Amacker; N Simon-Vermot; Axel Polack; Joachim Lingner; Riccardo Dalla-Favera
Direct activation of TERT transcription by c-MYC.
Nature genetics 1999;21(2):220-4.
1999: Kou-Juey Wu; Axel Polack; Riccardo Dalla-Favera
Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC.
Science (New York, N.Y.) 1999;283(5402):676-9.
1999: Ursula Zimber-Strobl; Lothar Strobl; H Höfelmayr; Bettina Kempkes; Martin Staege; Gerhard Laux; B Christoph; Axel Polack; Georg W Bornkamm
EBNA2 and c-myc in B cell immortalization by Epstein-Barr virus and in the pathogenesis of Burkitt's lymphoma.
Current topics in microbiology and immunology 1999;246():315-20; discussion 321.
1998: T Herrmann; D Schindler; H Tabe; Osamu Onodera; S Igarashi; Axel Polack; D Zehnpfennig
Molecular cloning, structural organization, sequence, chromosomal assignment, and expression of the mouse alpha-N-acetylgalactosaminidase gene.
Gene 1998;211(2):205-14.
1998: Markus Brielmeier; Jean-Marie Béchet; MH Falk; M Pawlita; Axel Polack; Georg W Bornkamm
Improving stable transfection efficiency: antioxidants dramatically improve the outgrowth of clones under dominant marker selection.
Nucleic acids research 1998;26(9):2082-5.
1998: Teresa Frisan; Victor Levitsky; Axel Polack; Maria Masucci
Phenotype-dependent differences in proteasome subunit composition and cleavage specificity in B cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3281-9.
1997: S Mũcke; Axel Polack; M Pawlita; D Zehnpfennig; Nadia Massoudi; Heribert Bohlen; W Doerfler; Georg W Bornkamm; Volker Diehl; Jürgen Wolf
Suitability of Epstein-Barr virus-based episomal vectors for expression of cytokine genes in human lymphoma cells.
Gene therapy 1997;4(2):82-92.
1996: Axel Polack; K Hörtnagel; A Pajic; B Christoph; B Baier; M Falk; Josef Mautner; C Geltinger; Georg W Bornkamm; Bettina Kempkes
c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10411-6.
1996: C Rottleb; C Hall; Georg W Bornkamm; Axel Polack
Structure-activity relationship of 17 structural analogues of n-butyric acid upon c-myc expression.
International journal of cancer. Journal international du cancer 1996;67(5):724-9.
1996: Josef Mautner; Georg W Bornkamm; Axel Polack
Long-range chromatin analysis of the human MYC locus by pulsed-field gel electrophoresis.
Genes, chromosomes & cancer 1996;16(4):247-53.
1996: Josef Mautner; U Behrends; K Hörtnagel; Markus Brielmeier; Wolfgang Hammerschmidt; Lothar Strobl; Georg W Bornkamm; Axel Polack
c-myc expression is activated by the immunoglobulin kappa-enhancers from a distance of at least 30 kb but not by elements located within 50 kb of the unaltered c-myc locus in vivo.
Oncogene 1996;12(6):1299-307.
1996: C Geltinger; K Hörtnagel; Axel Polack
TATA box and Sp1 sites mediate the activation of c-myc promoter P1 by immunoglobulin kappa enhancers.
Gene expression 1996;6(2):113-27.
1995: C Rottleb; G W Bornkamm; Axel Polack
Among 17 inducers of differentiation only sodium butyrate causes a permanent down-regulation of c-myc in Burkitt's lymphoma.
International journal of cancer. Journal international du cancer 1995;62(6):697-702.
1995: Guy Bouvier; Manfred Hergenhahn; Axel Polack; Georg W Bornkamm; G de Thé; Helmut Bartsch
Characterization of macromolecular lignins as Epstein-Barr virus inducer in foodstuff associated with nasopharyngeal carcinoma risk.
Carcinogenesis 1995;16(8):1879-85.
1995: K Hörtnagel; Josef Mautner; Lothar Strobl; D A Wolf; B Christoph; C Geltinger; Axel Polack
The role of immunoglobulin kappa elements in c-myc activation.
Oncogene 1995;10(7):1393-401.
1995: Josef Mautner; S Joos; Thomas Werner; Dirk Eick; Georg W Bornkamm; Axel Polack
Identification of two enhancer elements downstream of the human c-myc gene.
Nucleic acids research 1995;23(1):72-80.
1995: K Hörtnagel; Axel Polack; Josef Mautner; R Feederle; Georg W Bornkamm
Regulatory elements in the immunoglobulin kappa locus induce c-myc activation in Burkitt's lymphoma cells.
Current topics in microbiology and immunology 1995;194():415-22.
1994: J Schmidtler; K Dehne; Hans-Dieter Allescher; Volker Schusdziarra; M Classen; J J Holst; Axel Polack; Wolfgang Schepp
Rat parietal cell receptors for GLP-1-(7-36) amide: northern blot, cross-linking, and radioligand binding.
The American journal of physiology 1994;267(3 Pt 1):G423-32.
1993: Axel Polack; R Feederle; G Klobeck; K Hörtnagel
Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells.
The EMBO journal 1993;12(10):3913-20.
1993: Guy Bouvier; Manfred Hergenhahn; Axel Polack; Georg W Bornkamm; Helmut Bartsch
Validation of two test systems for detecting tumor promoters and EBV inducers: comparative responses of several agents in DR-CAT Raji cells and in human granulocytes.
Carcinogenesis 1993;14(8):1573-8.
1993: Lothar Strobl; Franz Kohlhuber; Josef Mautner; Axel Polack; Dirk Eick
Absence of a paused transcription complex from the c-myc P2 promoter of the translocation chromosome in Burkitt's lymphoma cells: implication for the c-myc P1/P2 promoter shift.
Oncogene 1993;8(6):1437-47.
1992: T W Apel; Josef Mautner; Axel Polack; Georg W Bornkamm; Dirk Eick
Two antisense promoters in the immunoglobulin mu-switch region drive expression of c-myc in the Burkitt's lymphoma cell line BL67.
Oncogene 1992;7(7):1267-71.
1992: Axel Polack; Gerhard Laux; Manfred Hergenhahn; U Kloz; H Roeser; E Hecker; Georg W Bornkamm
Short-term assays for detection of conditional cancerogens. I. Construction of DR-CAT Raji cells and some of their characteristics as tester cells.
International journal of cancer. Journal international du cancer 1992;50(4):611-6.
1991: Axel Polack; Lothar Strobl; R Feederle; M Schweizer; E Koch; Dirk Eick; H Wiegand; Georg W Bornkamm
The intron enhancer of the immunoglobulin kappa gene activates c-myc but does not induce the Burkitt-specific promoter shift.
Oncogene 1991;6(11):2033-40.
1991: E A Kirchner; Georg W Bornkamm; Axel Polack
Transcriptional activity across the Epstein-Barr virus genome in Raji cells during latency and after induction of an abortive lytic cycle.
The Journal of general virology 1991;72 ( Pt 10)():2391-8.
1991: Guy Bouvier; S Poirier; Y M Shao; Christian Malaveille; Hiroshi Ohshima; Axel Polack; Georg W Bornkamm; Y Zeng; G de-Thé; Helmut Bartsch
Epstein-Barr virus activators, mutagens and volatile nitrosamines in preserved food samples from high-risk areas for nasopharyngeal carcinoma.
IARC scientific publications 1991;(105):204-9.
1990: Dirk Eick; Axel Polack; E Kofler; Gilbert M Lenoir; A B Rickinson; Georg W Bornkamm
Expression of P0- and P3-RNA from the normal and translocated c-myc allele in Burkitt's lymphoma cells.
Oncogene 1990;5(9):1397-402.
1988: Dirk Eick; Axel Polack; E Kofler; Georg W Bornkamm
The block of elongation in c-myc exon 1 is abolished in Burkitt's lymphoma cell lines with variant translocation.
Oncogene 1988;3(4):397-403.
1988: G Laux; U K Freese; R Fischer; Axel Polack; E Kofler; Georg W Bornkamm
TPA-inducible Epstein-Barr virus genes in Raji cells and their regulation.
Virology 1988;162(2):503-7.
1988: B Henglein; Martin Lipp; P Hartl; S Adolph; Horst Hameister; Dirk Eick; Axel Polack; S Joos; F Baas; Gilbert M Lenoir
Burkitt's lymphoma variant translocations: distribution of chromosomal breakpoints and perturbated regulation of a mutated c-myc gene.
Current topics in microbiology and immunology 1988;141():165-71.
1987: Axel Polack; Dirk Eick; E Koch; Georg W Bornkamm
Truncation does not abrogate transcriptional downregulation of the c-myc gene by sodium butyrate in Burkitt's lymphoma cells.
The EMBO journal 1987;6(10):2959-64.
1987: J Reischig; D Bartsch; Axel Polack; Vladimír Vonka; Ivan Hirsch
Electron microscopy of binding of Epstein-Barr virus (EBV) nuclear antigen (EBNA-1) to EBV DNA.
Virology 1987;160(2):498-501.
1987: H Ikenberg; D Schwörer; A Pfleiderer; Axel Polack
Lack of c-myc gene amplification in genital tumours with different HPV status.
Lancet 1987;2(8558):577.
1987: Georg W Bornkamm; Axel Polack; Dirk Eick; R Berger; G M Lenoir
[Chromosome translocations and Epstein-Barr virus in Burkitt's lymphoma].
Onkologie 1987;10(4):196-204.
1987: Dirk Eick; R Berger; Axel Polack; Georg W Bornkamm
Transcription of c-myc in human mononuclear cells is regulated by an elongation block.
Oncogene 1987;2(1):61-5.
1986: Volker Schuster; B Matz; H Wiegand; Axel Polack; B Corsten; Dieter Neumann-Haefelin
Nucleic acid hybridization for detection of herpes viruses in clinical specimens.
Journal of medical virology 1986;19(3):277-86.
1984: K Takaki; Axel Polack; G W Bornkamm
Expression of a nuclear and a cytoplasmic Epstein-Barr virus early antigen after DNA transfer: cooperation of two distant parts of the genome for expression of the cytoplasmic antigen.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(14):4568-72.
1984: Axel Polack; G Hartl; U Zimber; U K Freese; G Laux; K Takaki; B Hohn; L Gissmann; Georg W Bornkamm
A complete set of overlapping cosmid clones of M-ABA virus derived from nasopharyngeal carcinoma and its similarity to other Epstein-Barr virus isolates.
Gene 1984;27(3):279-88.
1984: Axel Polack; H Delius; U Zimber; Georg W Bornkamm
Two deletions in the Epstein-Barr virus genome of the Burkitt lymphoma nonproducer line Raji.
Virology 1984;133(1):146-57.