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Stephen McMahon

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Lucile Moynié; Andrew D Smith; James W Taylor; Magnus S Alphey; Ruth Brenk; Fraser G Duthie; Alessa Koehnke; Stuart M Leckie; Stephen McMahon; James H Naismith
Structural insights into the mechanism and inhibition of the β-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa.
Lucille Moynie; James H Naismith; Tatyana Sandalova; Jason W Schmidberger; Robert Schnell; Magnus S Alphey; Wassila Abdelli Boulkerou; Cyprian Cukier; Fraser Duthie; William N Hunter; Agata Jacewicz; Jolanta Kopec; Huanting Liu; Stephen McMahon; Gunter Schneider
The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Sonia Paytubi; Catherine H Botting; Shirley Graham; Eugene V Koonin; Huanting Liu; Kira S Makarova; Stephen McMahon; James H Naismith; Malcolm F White
Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales.

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All Publications

2013: Lucile Moynié; Andrew D Smith; James W Taylor; Magnus S Alphey; Ruth Brenk; Fraser G Duthie; Alessa Koehnke; Stuart M Leckie; Stephen McMahon; James H Naismith
Structural insights into the mechanism and inhibition of the β-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa.
Journal of molecular biology 2013;425(2):365-77.
2013: Lucille Moynie; James H Naismith; Tatyana Sandalova; Jason W Schmidberger; Robert Schnell; Magnus S Alphey; Wassila Abdelli Boulkerou; Cyprian Cukier; Fraser Duthie; William N Hunter; Agata Jacewicz; Jolanta Kopec; Huanting Liu; Stephen McMahon; Gunter Schneider
The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta crystallographica. Section F, Structural biology and crystallization communications 2013;69(Pt 1):25-34.
2012: Sonia Paytubi; Catherine H Botting; Shirley Graham; Eugene V Koonin; Huanting Liu; Kira S Makarova; Stephen McMahon; James H Naismith; Malcolm F White
Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):E398-405.
2010: Robert M Hagan; Ragnar Björnsson; Stephen McMahon; Benjamin Schomburg; Vickie Braithwaite; Michael Bühl; James H Naismith; Ulrich Schwarz-Linek
NMR spectroscopic and theoretical analysis of a spontaneously formed Lys-Asp isopeptide bond.
Angewandte Chemie (International ed. in English) 2010;49(45):8421-5.
2010: Jonathan Lowther; Beverley A Yard; Kenneth A Johnson; Lester G Carter; Venugopal T Bhat; Marine C C Raman; David J Clarke; Britta Ramakers; Stephen McMahon; James H Naismith; Dominic J Campopiano
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.
Molecular bioSystems 2010;6(9):1682-93.
2009: Stephen McMahon; Gareth A Roberts; Kenneth A Johnson; Laurie P Cooper; Huanting Liu; John H White; Lester G Carter; Bansi Sanghvi; Muse Oke; Malcolm D Walkinshaw; Garry W Blakely; James H Naismith; David T F Dryden
Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance.
Nucleic acids research 2009;37(15):4887-97.
2009: Anne-Marie McRobbie; Lester G Carter; Melina Kerou; Huanting Liu; Stephen McMahon; Kenneth Alan Johnson; Muse Oke; James H Naismith; Malcolm White
Structural and functional characterisation of a conserved archaeal RadA paralog with antirecombinase activity.
Journal of molecular biology 2009;389(4):661-73.
2009: Stefan Schmelz; Nadia Kadi; Stephen McMahon; Lijiang Song; Daniel Oves-Costales; Muse Oke; Huanting Liu; Kenneth Alan Johnson; Lester G Carter; Catherine H Botting; Malcolm White; Gregory L Challis; James H Naismith
AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis.
Nature chemical biology 2009;5(3):174-82.
2008: Stephen McMahon; Muse Oke; Huanting Liu; Kenneth Alan Johnson; Lester Carter; Nadia Kadi; Malcolm White; Gregory L Challis; James H Naismith
Purification, crystallization and data collection of Pectobacterium chrysanthemi AcsD, a type A siderophore synthetase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 11):1052-5.
2008: Ian M Overton; C A Johannes van Niekerk; Lester G Carter; Alice Dawson; David M A Martin; Scott Cameron; Stephen McMahon; Malcolm White; William N Hunter; James H Naismith; Geoffrey J Barton
TarO: a target optimisation system for structural biology.
Nucleic acids research 2008;36(Web Server issue):W190-6.
2008: Huanting Liu; Jana Rudolf; Kenneth Alan Johnson; Stephen McMahon; Muse Oke; Lester Carter; Anne-Marie McRobbie; Sara E Brown; James H Naismith; Malcolm White
Structure of the DNA repair helicase XPD.
Cell 2008;133(5):801-12.
2008: Michael Fairhead; Kenneth Alan Johnson; Thomas Kowatz; Stephen McMahon; Lester G Carter; Muse Oke; Huanting Liu; James H Naismith; Christopher F van der Walle
Crystal structure and silica condensing activities of silicatein alpha-cathepsin L chimeras.
Chemical communications (Cambridge, England) 2008;(15):1765-7.
2008: Muse Oke; Rosalind Tan Yan Ching; Lester G Carter; Kenneth Alan Johnson; Huanting Liu; Stephen McMahon; Malcolm White; Carlos Bloch; Catherine H Botting; Martin A Walsh; Aishah A Latiff; Malcolm W Kennedy; Alan Cooper; James H Naismith
Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog.
Angewandte Chemie (International ed. in English) 2008;47(41):7853-6.
2007: Beverley A Yard; Lester G Carter; Kenneth Alan Johnson; Ian M Overton; Mark Dorward; Huanting Liu; Stephen McMahon; Muse Oke; Daphné Puech; Geoffrey J Barton; James H Naismith; Dominic J Campopiano
The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis.
Journal of molecular biology 2007;370(5):870-86.
2007: Jaldappagari Seetharamappa; Muse Oke; Huanting Liu; Stephen McMahon; Kenneth Alan Johnson; Lester Carter; Mark Dorward; Michal Zawadzki; Ian M Overton; C A Johannes van Niekirk; Shirley Graham; Catherine H Botting; Garry L Taylor; Malcolm White; Geoffrey J Barton; Peter J Coote; James H Naismith
Purification, crystallization and data collection of methicillin-resistant Staphylococcus aureus Sar2676, a pantothenate synthetase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 6):488-91.
2007: Jaldappagari Seetharamappa; Muse Oke; Huanting Liu; Stephen McMahon; Kenneth Alan Johnson; Lester Carter; Mark Dorward; Michal Zawadzki; Ian M Overton; C A Johannes van Niekirk; Shirley Graham; Catherine H Botting; Garry L Taylor; Malcolm White; Geoffrey J Barton; Peter J Coote; James H Naismith
Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 5):452-6.
2006: Stephen McMahon; Martin A Walsh; Rosalind Tan Yan Ching; Lester G Carter; Mark Dorward; Kenneth Alan Johnson; Huanting Liu; Muse Oke; Carlos Bloch; Malcolm W Kennedy; Aishah A Latiff; Alan Cooper; Garry L Taylor; Malcolm White; James H Naismith
Crystallization of Ranasmurfin, a blue-coloured protein from Polypedates leucomystax.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 11):1124-6.
2006: Gareth Williams; Kenneth Johnson; Jana Rudolf; Stephen McMahon; Lester Carter; Muse Oke; Huanting Liu; Garry L Taylor; Malcolm White; James H Naismith
Structure of the heterotrimeric PCNA from Sulfolobus solfataricus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 10):944-8.
2006: Andrew R McEwan; Huanting Liu; Muse Oke; Lester Carter; Helen Powers; Mark Dorward; Stephen McMahon; Malcolm White; James H Naismith
Overexpression, purification, crystallization and data collection of Sulfolobus solfataricus Sso6206, a novel highly conserved protein.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 3):228-30.
2006: Neal M Alto; Feng Shao; Cheri S Lazar; Renée L Brost; Gordon Chua; Seema Mattoo; Stephen McMahon; Partho Ghosh; Timothy R Hughes; Charles Boone; Jack E Dixon
Identification of a bacterial type III effector family with G protein mimicry functions.
Cell 2006;124(1):133-45.
2005: Stephen McMahon; Jason L Miller; Jeffrey A Lawton; Donald E Kerkow; Asher Hodes; maricus MR; Sergei R Doulatov; Eswar Narayanan; Andrej Sali; Jeff F Miller; Partho Ghosh
The C-type lectin fold as an evolutionary solution for massive sequence variation.
Nature structural & molecular biology 2005;12(10):886-92.
2001: David A R Sanders; AG Staines; Stephen McMahon; Mike R McNeil; Chris Whitfield; James H Naismith
UDP-galactopyranose mutase has a novel structure and mechanism.
Nature structural biology 2001;8(10):858-63.
2001: David A R Sanders; Stephen McMahon; G L Leonard; James H Naismith
Molecular placement of experimental electron density: a case study on UDP-galactopyranose mutase.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 10):1415-20.
2001: Miryam Asuncion; J N Barlow; J Pollard; AG Staines; Stephen McMahon; Wulf Blankenfeldt; David Gani; James H Naismith
Overexpression, purification, crystallization and data collection of 3-methylaspartase from Clostridium tetanomorphum.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 5):731-3.
1999: Marie-France Giraud; F M Gordon; Chris Whitfield; Paul Messner; Stephen McMahon; James H Naismith
Purification, crystallization and preliminary structural studies of dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase (RmlC), the third enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar typhimurium.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 3):706-8.
1999: Stephen McMahon; GA Leonard; LV Buchanan; Marie-France Giraud; James H Naismith
Initiating a crystallographic study of UDP-galactopyranose mutase from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 2):399-402.
1998: DN Moothoo; Stephen McMahon; S M Dimick; Eric J Toone; James H Naismith
Crystallization of succinylated concanavalin A bound to a synthetic bivalent ligand and preliminary structural analysis.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 5):1023-5.