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Kevin Gorski

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Publications

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T Doi; G Friberg; N Fuse; Kevin Gorski; C-P Hsu; T Kawaguchi; H Murakami; A Ohtsu; Y Onozawa; N Yamamoto; T Yoshino; N Boku; T Sasaki
Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors.
Anthony W Tolcher; John Sarantopoulos; Amita Patnaik; Kyriakos Papadopoulos; Chia-Chi Lin; Jordi Rodon; Barbara Murphy; Bruce Roth; Ian McCaffery; Kevin Gorski; Brianne Kaiser; Min Zhu; Hongjie Deng; Greg Friberg; Igor Puzanov
Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.
Calin D Dumitru; Mary A Antonysamy; Kevin Gorski; Dave D Johnson; Laxma G Reddy; Jody L Lutterman; Melissa M Piri; Joel Proksch; Sean M McGurran; Elaine A Egging; Felicia R Cochran; Kenneth E Lipson; Mark A Tomai; Gary W Gullikson
NK1.1+ cells mediate the antitumor effects of a dual Toll-like receptor 7/8 agonist in the disseminated B16-F10 melanoma model.

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All Publications

2011: T Doi; G Friberg; N Fuse; Kevin Gorski; C-P Hsu; T Kawaguchi; H Murakami; A Ohtsu; Y Onozawa; N Yamamoto; T Yoshino; N Boku; T Sasaki
Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors.
Cancer chemotherapy and pharmacology 2011;68(3):733-41.
2009: Anthony W Tolcher; John Sarantopoulos; Amita Patnaik; Kyriakos Papadopoulos; Chia-Chi Lin; Jordi Rodon; Barbara Murphy; Bruce Roth; Ian McCaffery; Kevin Gorski; Brianne Kaiser; Min Zhu; Hongjie Deng; Greg Friberg; Igor Puzanov
Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(34):5800-7.
2009: Calin D Dumitru; Mary A Antonysamy; Kevin Gorski; Dave D Johnson; Laxma G Reddy; Jody L Lutterman; Melissa M Piri; Joel Proksch; Sean M McGurran; Elaine A Egging; Felicia R Cochran; Kenneth E Lipson; Mark A Tomai; Gary W Gullikson
NK1.1+ cells mediate the antitumor effects of a dual Toll-like receptor 7/8 agonist in the disseminated B16-F10 melanoma model.
Cancer immunology, immunotherapy : CII 2009;58(4):575-87.
2009: Tianhong Wang; Qiong Jiang; Camie W Y Chan; Kevin Gorski; Erin McCadden; David Kardian; Drew M Pardoll; Katharine A Whartenby
Inhibition of activation-induced death of dendritic cells and enhancement of vaccine efficacy via blockade of MINOR.
Blood 2009;113(13):2906-13.
2007: Arkadiusz Z Dudek; Carla Yunis; Lester I Harrison; Sandeep Kumar; Ronald Hawkinson; Sarah Cooley; John P Vasilakos; Kevin Gorski; Jeffrey S Miller
First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7119-25.
2006: Kevin Gorski; Emily L Waller; Jacqueline Bjornton-Severson; John A Hanten; Christie L Riter; William C Kieper; Keith B Gorden; Jeffrey S Miller; John P Vasilakos; Mark A Tomai; Sefik Alkan
Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists.
International immunology 2006;18(7):1115-26.
2005: Keith B Gorden; Kevin Gorski; Sheila J Gibson; Ross M Kedl; William C Kieper; Xiaohong Qiu; Mark A Tomai; Sefik Alkan; John P Vasilakos
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1259-68.
2003: Kevin Gorski; Tae Kwang Shin; Emily Crafton; Mizuto Otsuji; Frédérique M Rattis; Xin Huang; Erin Kelleher; Loise Francisco; Drew M Pardoll; Haruo Tsuchiya
A set of genes selectively expressed in murine dendritic cells: utility of related cis-acting sequences for lentiviral gene transfer.
Molecular immunology 2003;40(1):35-47.
2003: Tae Kwang Shin; Gene Kennedy; Kevin Gorski; Haruo Tsuchiya; Haruhiko Koseki; Miyuki Azuma; Hideo Yagita; Lieping Chen; Jonathan D Powell; Drew M Pardoll; Franck Housseau
Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor.
The Journal of experimental medicine 2003;198(1):31-8.
2003: Yan Cui; Erin Kelleher; Erin Straley; Ephraim J Fuchs; Kevin Gorski; Hyam I Levitsky; Ivan Borrello; Curt I Civin; Stephen P Schoenberger; Linzhao Cheng; Drew M Pardoll; Katharine A Whartenby
Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells.
Nature medicine 2003;9(7):952-8.
2002: Katharine A Whartenby; Erin E Straley; Heeje Kim; Frederick Racke; Tanavde Vivek; Kevin Gorski; Linzhao Cheng; Drew M Pardoll; Curt I Civin
Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation.
Blood 2002;100(9):3147-54.
2002: Ryan A Wilcox; Andrei I Chapoval; Kevin Gorski; Mizuto Otsuji; Tae Kwang Shin; Dallas B Flies; Koji Tamada; Robert S Mittler; Haruo Tsuchiya; Drew M Pardoll; Lieping Chen
Cutting edge: Expression of functional CD137 receptor by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4262-7.
2001: Denise Golgher; Firouzeh Korangy; B Gao; Kevin Gorski; Elizabeth M Jaffee; Michael Edidin; Drew M Pardoll; Tim Elliott
An immunodominant MHC class II-restricted tumor antigen is conformation dependent and binds to the endoplasmic reticulum chaperone, calreticulin.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):147-55.
2001: S Y Tseng; Mizuto Otsuji; Kevin Gorski; Xin Huang; Jill E Slansky; Sara I Pai; A Shalabi; Tae Kwang Shin; Drew M Pardoll; Haruo Tsuchiya
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.
The Journal of experimental medicine 2001;193(7):839-46.
1998: David Fouts; G A Stryker; Kevin Gorski; Mark J Miller; T V Nguyen; Ruth A Wrightsman; Jerry E Manning
Evidence for four distinct major protein components in the paraflagellar rod of Trypanosoma cruzi.
The Journal of biological chemistry 1998;273(34):21846-55.