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Helena Alves

Research Profile

Physiology

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Europe

Anatomy

CD8-Positive T-Lymphocytes

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Publications

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António Morais; Maria José Peixoto; Helena Alves; Bruno Lima; Agostinho Marques; Luís Delgado
BTNL2 gene polymorphism associations with susceptibility and phenotype expression in sarcoidosis.
Laëtitia Michou; Paola Migliorini; Elisabeth Petit-Teixeira; Leo van de Putte; René Westhovens; Helena Alves; Alejandro Balsa; Thomas Bardin; Pilar Barrera; Stefano Bombardieri; François Cornélis; Jean-Michel Levesque; Maria J G Fernandes
A genetic association study of the CLEC12A gene in rheumatoid arthritis.
Roberto Díaz-Peña; Helena Alves; Ana M Aransay; Javier Ballina; Jacome Bruges-Armas; Eduardo Collantes; Juan Mulero; Fernando M Pimentel-Santos; Rubén Queiro; María Regueiro; Naiara Rodriguez-Ezpeleta; Alejandra Sánchez; Beatriz Suárez-Álvarez; Carlos López-Larrea
A high density SNP genotyping approach within the 19q13 chromosome region identifies an association of a CNOT3 polymorphism with ankylosing spondylitis.

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All Publications

2012: António Morais; Maria José Peixoto; Helena Alves; Bruno Lima; Agostinho Marques; Luís Delgado
BTNL2 gene polymorphism associations with susceptibility and phenotype expression in sarcoidosis.
Respiratory medicine 2012;106(12):1771-7.
2012: Laëtitia Michou; Paola Migliorini; Elisabeth Petit-Teixeira; Leo van de Putte; René Westhovens; Helena Alves; Alejandro Balsa; Thomas Bardin; Pilar Barrera; Stefano Bombardieri; François Cornélis; Jean-Michel Levesque; Maria J G Fernandes
A genetic association study of the CLEC12A gene in rheumatoid arthritis.
Joint, bone, spine : revue du rhumatisme 2012;79(5):451-6.
2012: Roberto Díaz-Peña; Helena Alves; Ana M Aransay; Javier Ballina; Jacome Bruges-Armas; Eduardo Collantes; Juan Mulero; Fernando M Pimentel-Santos; Rubén Queiro; María Regueiro; Naiara Rodriguez-Ezpeleta; Alejandra Sánchez; Beatriz Suárez-Álvarez; Carlos López-Larrea
A high density SNP genotyping approach within the 19q13 chromosome region identifies an association of a CNOT3 polymorphism with ankylosing spondylitis.
Annals of the rheumatic diseases 2012;71(5):714-7.
2011: Nuno Bettencourt; Mónica Carvalho; Amedeo Chiribiri; Helena Alves; Daniel Leite; Adelino Leite-Moreira; Eike Nagel; Susana Oliveira; João Rocha; Andreas Schuster; Andre Michael Toschke; Sónia Xará; Vasco Gama
Predictors of circulating endothelial progenitor cell levels in patients without known coronary artery disease referred for multidetector computed tomography coronary angiography.
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2011;30(10):753-60.
2011: Gustavo Rocha; Teresa Rodrigues; Bruno Lima; Elisa Proença; Helena Alves; Augusta Areias; Fátima Freitas; Hercília Guimarães
HLA and bronchopulmonary dysplasia susceptibility: a pilot study.
Disease markers 2011;31(4):199-203.
2011: P Xavier; P Aires; S Sampaio; C Mendes; M Monteiro; Helena Alves; G Oliveira
XM-ONE detection of endothelium cell antibodies identifies a subgroup of HLA-antibody negative patients undergoing acute rejection.
Transplantation proceedings 2011;43(1):91-4.
2011: Karen Dawidowicz; Yannick Allanore; Mickael Guedj; Céline Pierlot; Stefano Bombardieri; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Vitor Hugo Teixeira; Elisabeth Petit-Teixeira; Leo van de Putte; Piet van Riel; Bernard Prum; Thomas Bardin; Olivier Meyer; François Cornélis; Philippe Dieudé
The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype.
Annals of the rheumatic diseases 2011;70(1):117-21.
2009: Jana Burkhardt; Elisabeth Petit-Teixeira; Vitor Hugo Teixeira; Holger Kirsten; Sophie Garnier; Sandra Ruehle; Christian Oeser; Grit Wolfram; Markus Scholz; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy R Radstake; Piet Van Riel; Leo van de Putte; Thomas Bardin; Bernard Prum; Ulrike Buchegger-Podbielski; Frank Emmrich; Inga Melchers; François Cornelis; Peter Ahnert
Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis.
The Journal of rheumatology 2009;36(10):2149-57.
2009: Paula D P Xavier; Helena Alves; José G G de Oliveira; Carla A R Santos-Araújo; Roberto L F Roncon-Albuquerque; Adelino F Leite-Moreira; Andrea S L Ribeiro; Susana M M Sampaio-Norton
Direct downregulation of Toll-like receptors by anti-IL-2 alpha chain-receptor antibody in cadaver kidney transplant recipients.
Transplantation 2009;88(6):848-9.
2009: V Hugo Teixeira; P Dieudé; L Michou; P Migliorini; A Balsa; R Westhovens; P Barrera; Helena Alves; C Vaz; M Fernandes; D Pascual-Salcedo; S Bombardieri; J Dequeker; T R Radstake; P Van Riel; L van de Putte; A Lopes-Vaz; T Bardin; F Cornélis; E Petit-Teixeira
Association study of the RANK locus in white European rheumatoid arthritis families.
Annals of the rheumatic diseases 2009;68(3):448-9.
2009: Vitor Hugo Teixeira; Celine Pierlot; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Carlos Vaz; Manuela Fernandes; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy R Radstake; Piet Van Riel; Leo van de Putte; Antonio Lopes-Vaz; Thomas Bardin; Bernard Prum; François Cornélis; Elisabeth Petit-Teixeira
Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study.
Arthritis research & therapy 2009;11(2):R45.
2008: António Morais; Helena Alves; Bruno Lima; Luís Delgado; Ricardo Gonçalves; Sandra Tafulo
HLA class I and II and TNF-alpha gene polymorphisms in sarcoidosis patients.
Revista portuguesa de pneumologia 2008;14(6):727-46.
2008: Fina A S Kurreeman; D Rocha; Jeanine J Houwing-Duistermaat; S Vrijmoet; V H Teixeira; P Migliorini; A Balsa; R Westhovens; Pilar Barrera; Helena Alves; C Vaz; M Fernandes; D Pascual-Salcedo; L Michou; S Bombardieri; Timothy Radstake; P van Riel; L van de Putte; A Lopes-Vaz; B Prum; T Bardin; Ivo Gut; F Cornelis; Tom W J Huizinga; E Petit-Teixeira; René E M Toes
Replication of the tumor necrosis factor receptor-associated factor 1/complement component 5 region as a susceptibility locus for rheumatoid arthritis in a European family-based study.
Arthritis and rheumatism 2008;58(9):2670-4.
2007: Jorge Vieira; Carla S Cardoso; J Pinto; K Patil; P Brazdil; Eugénia Cruz; Claudia Mascarenhas; Rosa Lacerda; A Gartner; Susana Almeida; Helena Alves; Graça Porto
A putative gene located at the MHC class I region around the D6S105 marker contributes to the setting of CD8+ T-lymphocyte numbers in humans.
International journal of immunogenetics 2007;34(5):359-67.
2007: M Ozawa; P I Terasaki; J H Lee; R Castro; J Alberu; C Alonso; I Alvarez; R Toledo; Helena Alves; M Monterio; J Teixeira; P Campbell; M Ciszek; D Charron; C Gautreau; F Christiansen; R Conca; B Gomez; F Monteon; H Grosse-Wilde; F Heinemann; I Humar; M Kamoun; P Kimball; T Kobayashi; P Kupatawintu; S Leech; W LeFor; N Mehra; A Panigrahi; E Naumova; Douglas J Norman; A Piazza; F Poli; B Colombo; R Roy; C Schonemann; G Sireci; K Tanabe; H Ishida; E Van den Berg-Loonen; A Zeevi
14th International HLA and Immunogenetics Workshop: report on the Prospective Chronic Rejection Project.
Tissue antigens 2007;69 Suppl 1():174-9.
2007: Laëtitia Michou; Sandra Lasbleiz; Anne-Christine Rat; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Céline Pierlot; Elodie Glikmans; Sophie Garnier; Jean Dausset; Carlos Vaz; Manuela Fernandes; Elisabeth Petit-Teixeira; Isabelle Lemaire; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy Radstake; Piet Van Riel; L B A Van De Putte; Antonio Lopes-Vaz; Bernard Prum; Thomas Bardin; Philippe Dieudé; François Cornélis
Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(5):1649-54.
2007: M Ozawa; P I Terasaki; R Castro; J Alberu; L Morales-Buenrostro; I Alvarez; R Toledo; Helena Alves; M Monteiro; J Teixeira; P Campbell; M Ciszek; D Charron; C Gautreau; F Christiansen; L Langan; R Conca; H Grosse-Wilde; F Heinemann; M Kamoun; T Kobayashi; P Kupatawintu; W LeFor; N Mehra; A Panigrahi; Douglas J Norman; A Piazza; F Poli; R Roy; C Schonemann; N Lachmann; G Sireci; K Tanabe; H Ishida; E Van den Berg-Loonen; A Zeevi
14th International HLA and Immunogenetics Workshop Prospective Chronic Rejection Project: a three-year follow-up analysis.
Clinical transplants 2007;():255-60.
2007: Laurent Jacq; Sophie Garnier; Philippe Dieudé; Laëtitia Michou; Céline Pierlot; Paola Migliorini; Alejandro Balsa; René Westhovens; Pilar Barrera; Helena Alves; Carlos Vaz; Manuela Fernandes; Dora Pascual-Salcedo; Stefano Bombardieri; Jan Dequeker; Timothy Radstake; Piet Van Riel; Leo van de Putte; Antonio Lopes-Vaz; Elodie Glikmans; Sandra Barbet; Sandra Lasbleiz; Isabelle Lemaire; Patrick Quillet; Pascal Hilliquin; Vitor Hugo Teixeira; Elisabeth Petit-Teixeira; Hamdi Mbarek; Bernard Prum; Thomas Bardin; François Cornélis
The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study.
Arthritis research & therapy 2007;9(4):R63.
2006: Eugénia Cruz; Jorge Vieira; Susana Almeida; Rosa Lacerda; Andrea Gartner; Carla S Cardoso; Helena Alves; Graça Porto
A study of 82 extended HLA haplotypes in HFE-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overload.
BMC medical genetics 2006;7():16.
2005: José G G Oliveira; Manuela S Monteiro; José F Teixeira; Ermelinda Osório; Susana M S Norton; Helena Alves; Manuel Pestana
Humoral immune response after kidney transplantation is enhanced by acute rejection and urological obstruction and is down-regulated by mycophenolate mofetil treatment.
Transplant international : official journal of the European Society for Organ Transplantation 2005;18(11):1286-91.
2004: Eugénia Cruz; Jorge Vieira; Ricardo Gonçalves; Helena Alves; Susana Almeida; Pedro Rodrigues; Rosa Lacerda; Graça Porto
Involvement of the major histocompatibility complex region in the genetic regulation of circulating CD8 T-cell numbers in humans.
Tissue antigens 2004;64(1):25-34.
2002: Carla S Cardoso; Helena Alves; Mónica Mascarenhas; Ricardo Gonçalves; Pedro Oliveira; Pedro Rodrigues; Eugénia Cruz; Maria de Sousa; Graça Porto
Co-selection of the H63D mutation and the HLA-A29 allele: a new paradigm of linkage disequilibrium?
Immunogenetics 2002;53(12):1002-8.
2001: Pilar Barrera; S Fauré; JF Prud'homme; Alejandro Balsa; Paola Migliorini; Daniele Chimenti; Timothy Radstake; L B A Van De Putte; Dora Pascual-Salcedo; René Westhovens; K Maenaut; Helena Alves; Antonio Lopes-Vaz; C Stravopoulos; Marilyn Spyropoulou; P Fritz; Thomas Bardin; Dominique Charron; Virginia Lepage; Maria Martinez; François Cornélis
European genetic study on rheumatoid arthritis: is there a linkage of the interleukin-1 (IL-1), IL-10 or IL-4 genes to RA?
Clinical and experimental rheumatology 2001;19(6):709-14.
2001: A Martinez; Miguel Fernandez-Arquero; Alejandro Balsa; Ana Rubio; Helena Alves; Dora Pascual-Salcedo; E Martin-Mola; Emilio G De-la-Concha
Primary association of a MICA allele with protection against rheumatoid arthritis.
Arthritis and rheumatism 2001;44(6):1261-5.
2001: Alejandro Balsa; Pilar Barrera; René Westhovens; Helena Alves; K Maenaut; Dora Pascual-Salcedo; François Cornélis; Thomas Bardin; Lucrezia Riente; Timothy Radstake; G de Almeida; Virginia Lepage; C Stravopoulos; M Spaepen; Antonio Lopes-Vaz; D Charron; M Martinez; J F Prudhomme; Paola Migliorini; P Fritz
Clinical and immunogenetic characteristics of European multicase rheumatoid arthritis families.
Annals of the rheumatic diseases 2001;60(6):573-6.
2001: Pilar Barrera; Alejandro Balsa; Helena Alves; René Westhovens; K Maenaut; François Cornélis; P Fritz; Thomas Bardin; M Ceu Maia; Antonio Lopes-Vaz; Dora Pascual-Salcedo; Emilio G De-la-Concha; Timothy Radstake; L B A Van De Putte; Paola Migliorini; J F Prudhomme; Dominique Charron; Marilyn Spyropoulou; A Mendes; M Spaepen; Maria Martinez; C Stavropoulos
Noninherited maternal antigens do not increase the susceptibility for familial rheumatoid arthritis. European Consortium on Rheumatoid Arthritis Families (ECRAF).
The Journal of rheumatology 2001;28(5):968-74.
2000: Alfonso Martínez; Miguel Fernández-Arquero; Dora Pascual-Salcedo; Laura Conejero; Helena Alves; Alejandro Balsa; Emilio G De-la-Concha
Primary association of tumor necrosis factor-region genetic markers with susceptibility to rheumatoid arthritis.
Arthritis and rheumatism 2000;43(6):1366-70.
2000: Fernando A. Arosa; Graça Porto; José Manuel Cabeda; Rosa Lacerda; D Resende; Eugénia Cruz; C Cardoso; M Fonseca; C Simões; Pedro Rodrigues; Fernanda Bravo; José Carlos Oliveira; Helena Alves; J Fraga; Benvindo Justiça; Maria de Sousa
Expansions of CD8+CD28- and CD8+TcRVbeta5.2+ T cells in peripheral blood of heavy alcohol drinkers.
Alcoholism, clinical and experimental research 2000;24(4):519-27.
2000: Pilar Barrera; Alejandro Balsa; Helena Alves; René Westhovens; K Maenaut; François Cornélis; P Fritz; Thomas Bardin; G de Almeida; Antonio Lopes-Vaz; Dora Pascual-Salcedo; Emilio G De-la-Concha; Timothy Radstake; L B A Van De Putte; Paola Migliorini; JF Prud'homme; Dominique Charron; Marilyn Spyropoulou; A Mendes; M Spaepen; Maria Martinez; Virginia Lepage; C Stravopoulos
Noninherited maternal antigens do not play a role in rheumatoid arthritis susceptibility in Europe. European Consortium on Rheumatoid Arthritis Families.
Arthritis and rheumatism 2000;43(4):758-64.
1998: F Cornélis; S Fauré; M Martinez; J F Prud'homme; P Fritz; C Dib; Helena Alves; P Barrera; Niek de Vries; A Balsa; D Pascual-Salcedo; K Maenaut; R Westhovens; P Migliorini; T H Tran; A Delaye; N Prince; C Lefevre; G Thomas; M Poirier; S Soubigou; O Alibert; S Lasbleiz; S Fouix; C Bouchier; Frédéric Lioté; M N Loste; V Lepage; D Charron; G Gyapay; A Lopes-Vaz; D Kuntz; T Bardin; J Weissenbach
New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10746-50.
1998: Graça Porto; Helena Alves; Pedro Rodrigues; José Manuel Cabeda; C Portal; A Ruivo; Benvindo Justiça; R Wolff; Maria de Sousa
Major histocompatibility complex class I associations in iron overload: evidence for a new link between the HFE H63D mutation, HLA-A29, and non-classical forms of hemochromatosis.
Immunogenetics 1998;47(5):404-10.
1997: Anabela Rodrigues; T Morgado; J Areias; Frederico Silvestre; L Pinho; Helena Alves; A Castro-Henriques; António Morais Sarmento; Serafim Guimarães
Limited benefits of INF-alpha therapy in renal graft candidates with chronic viral hepatitis B or C.
Transplantation proceedings 1997;29(1-2):777-80.
1997: Graça Porto; C Vicente; MA Teixeira; O Martins; José Manuel Cabeda; Rosa Lacerda; C Goncalves; J Fraga; G Macedo; B M Silva; Helena Alves; Benvindo Justiça; Maria de Sousa
Relative impact of HLA phenotype and CD4-CD8 ratios on the clinical expression of hemochromatosis.
Hepatology (Baltimore, Md.) 1997;25(2):397-402.