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Sandra Orsulic

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Nicole D Fleming; Beth Y Karlan; Carl W Miller; Hoorig Nassanian; Sandra Orsulic; Hasmik Agadjanian; Christine S Walsh
Xeroderma pigmentosum complementation group C single-nucleotide polymorphisms in the nucleotide excision repair pathway correlate with prolonged progression-free survival in advanced ovarian cancer.
Barbie Taylor-Harding; Hasmik Agadjanian; X Guo; Beth Y Karlan; S Kwon; C Miller; Hoorig Nassanian; Sandra Orsulic; Christine S Walsh
Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment.
David A Engler; David M Gershenson; Joe W Gray; Jenny Gross; Whitfield B Growdon; Sumeet Gupta; Beth Y Karlan; Wen-Lin Kuo; Serena F Allred; Michael J Birrer; Michael T Deavers; Ronny I Drapkin; Mai Nitta; Sandra Orsulic; Bo R Rueda; Petra A Sergent; Gayatry Mohapatra
Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.

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All Publications

2012: Nicole D Fleming; Beth Y Karlan; Carl W Miller; Hoorig Nassanian; Sandra Orsulic; Hasmik Agadjanian; Christine S Walsh
Xeroderma pigmentosum complementation group C single-nucleotide polymorphisms in the nucleotide excision repair pathway correlate with prolonged progression-free survival in advanced ovarian cancer.
Cancer 2012;118(3):689-97.
2012: Barbie Taylor-Harding; Hasmik Agadjanian; X Guo; Beth Y Karlan; S Kwon; C Miller; Hoorig Nassanian; Sandra Orsulic; Christine S Walsh
Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment.
British journal of cancer 2012;106(2):333-43.
2012: David A Engler; David M Gershenson; Joe W Gray; Jenny Gross; Whitfield B Growdon; Sumeet Gupta; Beth Y Karlan; Wen-Lin Kuo; Serena F Allred; Michael J Birrer; Michael T Deavers; Ronny I Drapkin; Mai Nitta; Sandra Orsulic; Bo R Rueda; Petra A Sergent; Gayatry Mohapatra
Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.
PloS one 2012;7(2):e30996.
2011: Elda Righi; Satoshi Kashiwagi; Jianping Yuan; Michael Santosuosso; Pierre Leblanc; Rachel Ingraham; Benjamin Forbes; Beth Edelblute; Brian Collette; Deyin Xing; Magdalena Kowalski; Maria Cristina Mingari; Fabrizio Vianello; Michael Birrer; Sandra Orsulic; Glenn Dranoff; Mark C Poznansky
CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer.
Cancer research 2011;71(16):5522-34.
2011: Michael S Goldberg; Deyin Xing; Yin Ren; Sandra Orsulic; Sangeeta N Bhatia; Phillip A Sharp
Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(2):745-50.
2011: Dong-Joo Cheon; Sandra Orsulic
Mouse models of cancer.
Annual review of pathology 2011;6():95-119.
2010: Barbie Taylor-Harding; Sandra Orsulic; Beth Y Karlan; Andrew J Li
Fluvastatin and cisplatin demonstrate synergistic cytotoxicity in epithelial ovarian cancer cells.
Gynecologic oncology 2010;119(3):549-56.
2010: Chad A Hall; Runsheng Wang; Jiangyong Miao; Esther Oliva; Xiaoyun Shen; Thomas Wheeler; Susan G Hilsenbeck; Sandra Orsulic; Scott Goode
Hippo pathway effector Yap is an ovarian cancer oncogene.
Cancer research 2010;70(21):8517-25.
2010: Nageatte Ibrahim; Lei He; Chee-Onn Leong; Deyin Xing; Beth Y Karlan; Elizabeth M Swisher; Bo R Rueda; Sandra Orsulic; Leif W Ellisen
BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma.
Cancer research 2010;70(18):7155-65.
2010: Rajasekhar Singavarapu; Natalie Buchinsky; Dong-Joo Cheon; Sandra Orsulic
Whole ovary immunohistochemistry for monitoring cell proliferation and ovulatory wound repair in the mouse.
Reproductive biology and endocrinology : RB&E 2010;8():98.
2010: Shan Deng; Xiaojun Yang; Heini Lassus; Shun Liang; Sippy Kaur; Qunrui Ye; Chunsheng Li; Li-Ping Wang; Katherine F Roby; Sandra Orsulic; Denise C Connolly; Youcheng Zhang; kathleen montone; Ralf Bützow; George Coukos; Lin Zhang
Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers.
PloS one 2010;5(4):e10277.
2009: Deyin Xing; George Scangas; Mai Nitta; Lei He; Xuan Xu; Yevgeniya J M Ioffe; Paul-Joseph Aspuria; Cyrus V Hedvat; Matthew L Anderson; Esther Oliva; Beth Y Karlan; Gayatry Mohapatra; Sandra Orsulic
A role for BRCA1 in uterine leiomyosarcoma.
Cancer research 2009;69(21):8231-5.
2008: Ying Wang; Dong-Joo Cheon; Zhen Lu; Sheena L Cunningham; Chun-Ming Chen; Robert Z Luo; Deyin Xing; Sandra Orsulic; Robert C Bast; Richard R Behringer
MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse.
Differentiation; research in biological diversity 2008;76(10):1081-92.
2008: Jiangyong Miao; David Mu; Burce Ergel; Rajasekhar Singavarapu; Zhenfeng Duan; Scott Powers; Esther Oliva; Sandra Orsulic
Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model.
International journal of cancer. Journal international du cancer 2008;123(9):2041-7.
2008: Hideo Sakamoto; Anne M Friel; Antony W Wood; Lankai Guo; Ana Ilic; Michael Seiden; Daniel C Chung; Maureen P Lynch; takehiro serikawa; Elizabeth G Munro; Esther Oliva; Sandra Orsulic; Sandra D Kirley; Rosemary Foster; Lawrence R Zukerberg; Bo R Rueda
Mechanisms of Cables 1 gene inactivation in human ovarian cancer development.
Cancer biology & therapy 2008;7(2):180-88.
2007: Jiangyong Miao; Zuncai Wang; Heather Provencher; Beth Muir; Sonika Dahiya; Erin Carney; Chee-Onn Leong; Dennis C Sgroi; Sandra Orsulic
HOXB13 promotes ovarian cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):17093-8.
2007: Takiko Daikoku; Susanne Tranguch; Anindita Chakrabarty; Dingzhi Wang; Dineo Khabele; Sandra Orsulic; Jason D Morrow; Raymond DuBois; Sudhansu K Dey
Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer.
Cancer research 2007;67(11):5285-92.
2007: Devyani Chaudhuri; Sandra Orsulic; Badithe T Ashok
Antiproliferative activity of sulforaphane in Akt-overexpressing ovarian cancer cells.
Molecular cancer therapeutics 2007;6(1):334-45.
2006: Deyin Xing; Sandra Orsulic
A mouse model for the molecular characterization of brca1-associated ovarian carcinoma.
Cancer research 2006;66(18):8949-53.
2005: Stephan Gasser; Sandra Orsulic; Eric J Brown; David H Raulet
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.
Nature 2005;436(7054):1186-90.
2005: Deyin Xing; Sandra Orsulic
Modeling resistance to pathway-targeted therapy in ovarian cancer.
Cell cycle (Georgetown, Tex.) 2005;4(8):1004-6.
2005: Deyin Xing; Sandra Orsulic
A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(19):6936-41.
2005: Takiko Daikoku; Dingzhi Wang; Susanne Tranguch; Jason D Morrow; Sandra Orsulic; Raymond DuBois; Sudhansu K Dey
Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer.
Cancer research 2005;65(9):3735-44.
2002: Sandra Orsulic
An RCAS-TVA-based approach to designer mouse models.
Mammalian genome : official journal of the International Mammalian Genome Society 2002;13(10):543-7.
2002: Sandra Orsulic; Yi Li; Robert A Soslow; Lynn Vitale-cross; J Silvio Gutkind; Harold Varmus
Induction of ovarian cancer by defined multiple genetic changes in a mouse model system.
Cancer cell 2002;1(1):53-62.
2000: Sandra Orsulic; Rolf Kemler
Expression of Eph receptors and ephrins is differentially regulated by E-cadherin.
Journal of cell science 2000;113 ( Pt 10)():1793-802.
1999: Galen H Fisher; Sandra Orsulic; Eric C Holland; WP Hively; Yi Li; Brian C Lewis; Bart Williams; Harold Varmus
Development of a flexible and specific gene delivery system for production of murine tumor models.
Oncogene 1999;18(38):5253-60.
1999: Sandra Orsulic; O Huber; H Aberle; S Arnold; Rolf Kemler
E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation.
Journal of cell science 1999;112 ( Pt 8)():1237-45.
1999: RT Cox; LM Pai; J R Miller; Sandra Orsulic; J Stein; C A McCormick; Y Audeh; W Wang; Randall T Moon; Mark Peifer
Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own.
Development (Cambridge, England) 1999;126(6):1327-35.
1997: LM Pai; Sandra Orsulic; Amy Bejsovec; Mark Peifer
Negative regulation of Armadillo, a Wingless effector in Drosophila.
Development (Cambridge, England) 1997;124(11):2255-66.
1996: Sandra Orsulic; Mark Peifer
Cell-cell signalling: Wingless lands at last.
Current biology : CB 1996;6(11):1363-7.
1996: Sandra Orsulic; Mark Peifer
An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling.
The Journal of cell biology 1996;134(5):1283-300.
1994: Sandra Orsulic; Mark Peifer
A method to stain nuclei of Drosophila for confocal microscopy.
BioTechniques 1994;16(3):441-7.
1993: Mark Peifer; Sandra Orsulic; D Sweeton; Eric Wieschaus
A role for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis.
Development (Cambridge, England) 1993;118(4):1191-207.
1993: Mark Peifer; Sandra Orsulic; L M Pai; Joseph Loureiro
A model system for cell adhesion and signal transduction in Drosophila.
Development (Cambridge, England). Supplement 1993;():163-76.