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Fenghuang Zhan

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Niina Veitonmäki; Ye Yang; Ming Zeng; Fenghuang Zhan; Lena Danielsson; Markus Hansson; Mathilda Kovacek; Zhan-Chun Li; Anne Ljungars; Tobias Löfstedt; Andrea Lundqvist; Linda Mårtensson; Titti Martinsson-Niskanen; Annika Sundberg; Ingrid Teige; Guido Tricot; Björn Frendéus
A human icam-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
Wen Zhou; David Bearss; Tiehua Chen; Rodney Miles; Mohamed E Salama; Shashirekha Shetty; Lei Shi; Guido Tricot; He Wang; Jiliang Xia; Wei Xiong; Hongwei Xu; Ye Yang; Maurizio Zangari; Zhaoyang Zeng; Fenghuang Zhan
NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.
Maurizio Zangari; Fenghuang Zhan; Evangelos Terpos; Guido Tricot
Impact of bortezomib on bone health in myeloma: a review of current evidence.

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All Publications

2013: Niina Veitonmäki; Ye Yang; Ming Zeng; Fenghuang Zhan; Lena Danielsson; Markus Hansson; Mathilda Kovacek; Zhan-Chun Li; Anne Ljungars; Tobias Löfstedt; Andrea Lundqvist; Linda Mårtensson; Titti Martinsson-Niskanen; Annika Sundberg; Ingrid Teige; Guido Tricot; Björn Frendéus
A human icam-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
Cancer cell 2013;23(4):502-15.
2013: Wen Zhou; David Bearss; Tiehua Chen; Rodney Miles; Mohamed E Salama; Shashirekha Shetty; Lei Shi; Guido Tricot; He Wang; Jiliang Xia; Wei Xiong; Hongwei Xu; Ye Yang; Maurizio Zangari; Zhaoyang Zeng; Fenghuang Zhan
NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.
Cancer cell 2013;23(1):48-62.
2012: Maurizio Zangari; Fenghuang Zhan; Evangelos Terpos; Guido Tricot
Impact of bortezomib on bone health in myeloma: a review of current evidence.
Cancer treatment reviews 2012;38(8):968-80.
2012: Maurizio Zangari; Fenghuang Zhan; Tamara Berno; Guido Tricot; Louis Fink
Mechanisms of thrombosis in paraproteinemias: the effects of immunomodulatory drugs.
Seminars in thrombosis and hemostasis 2012;38(8):768-79.
2011: Xiaosong Wu; Fenghuang Zhan; Junhua Zheng; Yi Tao; Rong Wei; Gongwen Ai; Ying Han; Jun Hou; Xiuqin Meng; Yang Shao; Jumei Shi
Proteasome inhibitor lactacystin augments natural killer cell cytotoxicity of myeloma via downregulation of HLA class I.
Biochemical and biophysical research communications 2011;415(1):187-92.
2011: Maurizio Zangari; Fenghuang Zhan; Tamara Berno; Kenneth M Boucher; Guido Tricot; Louis Fink
Activated protein C resistance as measured by residual factor V after Russell's viper venom and activated protein C treatment analyzed as a continuous variable in multiple myeloma and normal controls.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2011;22(5):420-3.
2011: Maurizio Zangari; Fenghuang Zhan; Suzanne Trudel; Ravi Vij; Luhua Wang; Monette Aujay; Nizar Bahlis; Andrew Belch; Tamara Berno; Kristina L Hetherington; Sundar Jagannath; Andrzej Jakubowiak; A Keith Stewart; Vishal Kukreti; Sagar Lonial; Robert Z Orlowski; David Siegel; Seema Singhal; George Somlo; Guido Tricot
Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patients.
European journal of haematology 2011;86(6):484-7.
2011: Maurizio Zangari; Louis Fink; Fenghuang Zhan; Guido Tricot
Low venous thromboembolic risk with bortezomib in multiple myeloma and potential protective effect with thalidomide/lenalidomide-based therapy: review of data from phase 3 trials and studies of novel combination regimens.
Clinical lymphoma, myeloma & leukemia 2011;11(2):228-36.
2011: Maurizio Zangari; Shmuel Yaccoby; Lisa M Pappas; Federica Cavallo; Naveen Sanath Kumar; Subramanian Ranganathan; Larry J Suva; J Michael Gruenwald; Steven Kern; Fenghuang Zhan; Dixie Esseltine; Guido Tricot
A prospective evaluation of the biochemical, metabolic, hormonal and structural bone changes associated with bortezomib response in multiple myeloma patients.
Haematologica 2011;96(2):333-6.
2011: Richard Dela Cruz; Guido Tricot; Maurizio Zangari; Fenghuang Zhan
Progress in myeloma stem cells.
American journal of blood research 2011;1(2):135-45.
2010: Xiaosong Wu; Jumei Shi; Yi Wu; Yi Tao; Jun Hou; Xiuqin Meng; Xiaojing Hu; Ying Han; Wei Jiang; Siyuan Tang; Maurizio Zangari; Guido Tricot; Fenghuang Zhan
Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2.
Cancer biology & therapy 2010;10(11):1201-14.
2010: Maurizio Zangari; Fenghuang Zhan; Guido Tricot
Bone and paraproteinemias.
Current opinion in supportive and palliative care 2010;4(3):195-9.
2010: Lei Shi; Siqing Wang; Maurizio Zangari; Hongwei Xu; Thai M Cao; Chunjiao Xu; Yong Wu; Fang Xiao; Yinghong Liu; Ye Yang; Mohamed Salama; Guiyuan Li; Guido Tricot; Fenghuang Zhan
Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance.
Oncotarget 2010;1(1):22-33.
2010: Amy Heerema-McKenney; James Waldron; Steven Hughes; Fenghuang Zhan; Jeffery Sawyer; Bart Barlogie; John D Shaughnessy
Clinical, immunophenotypic, and genetic characterization of small lymphocyte-like plasma cell myeloma: a potential mimic of mature B-cell lymphoma.
American journal of clinical pathology 2010;133(2):265-70.
2010: Lijuan Chen; Siqing Wang; Yiming Zhou; Xiaosong Wu; Igor Entin; Joshua Epstein; Shmuel Yaccoby; Wei Xiong; Bart Barlogie; John D Shaughnessy; Fenghuang Zhan
Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma.
Blood 2010;115(1):61-70.
2010: Maurizio Zangari; Guido Tricot; Latha Polavaram; Fenghuang Zhan; Ashlie Finlayson; Robert Knight; Tommy Fu; Donna Weber; Meletios A Dimopoulos; Ruben Niesvizky; Louis Fink
Survival effect of venous thromboembolism in patients with multiple myeloma treated with lenalidomide and high-dose dexamethasone.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(1):132-5.
2009: Maurizio Zangari; Louis M Fink; Francesca Elice; Fenghuang Zhan; Dorothy M Adcock; Guido J Tricot
Thrombotic events in patients with cancer receiving antiangiogenesis agents.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(29):4865-73.
2009: Frits van Rhee; Susann M Szmania; Myles Dillon; Anne M van Abbema; Xin Li; Mary K Stone; Tarun K Garg; JuMei Shi; Amberly M Moreno-Bost; Rui Yun; Balaji Balasa; Bishwa Ganguly; Debra Chao; Audie G Rice; Fenghuang Zhan; John D Shaughnessy; Bart Barlogie; Shmuel Yaccoby; Daniel E H Afar
Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma.
Molecular cancer therapeutics 2009;8(9):2616-24.
2009: Ariel Anguiano; Sascha A Tuchman; Chaitanya R Acharya; Kelly Salter; Cristina Gasparetto; Fenghuang Zhan; Madhav Dhodapkar; Joseph R Nevins; Bart Barlogie; John D Shaughnessy; Anil Potti
Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(25):4197-203.
2009: Siqing Wang; Guido Tricot; Lei Shi; Wei Xiong; Zhaoyang Zeng; Hongwei Xu; Maurizio Zangari; Bart Barlogie; John D Shaughnessy; Fenghuang Zhan
RARalpha2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma.
Blood 2009;114(3):600-7.
2009: Anne-Tove Brenne; Unn-Merete Fagerli; John D Shaughnessy; Thea Kristin Våtsveen; Torstein Baade Rø; Hanne Hella; Fenghuang Zhan; Bart Barlogie; Anders Sundan; Magne Børset; Anders Waage
High expression of BCL3 in human myeloma cells is associated with increased proliferation and inferior prognosis.
European journal of haematology 2009;82(5):354-63.
2008: Wei Xiong; Xiaosong Wu; Sarah Starnes; Sarah K Johnson; Jeffrey Haessler; Siqing Wang; Lijuan Chen; Bart Barlogie; John D Shaughnessy; Fenghuang Zhan
An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma.
Blood 2008;112(10):4235-46.
2008: Bart Burington; Bart Barlogie; Fenghuang Zhan; John Crowley; John D Shaughnessy
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4821-9.
2008: Eric D Hsi; Roxanne Steinle; Balaji Balasa; Susann Szmania; Aparna Draksharapu; Benny P Shum; Mahrukh Huseni; David Powers; Amulya Nanisetti; Yin Zhang; Audie G Rice; A van Abbema; Melanie Wong; Gao Liu; Fenghuang Zhan; Myles Dillon; Shihao Chen; Susan Rhodes; Franklin Fuh; Naoya Tsurushita; Shankar Kumar; Vladimir Vexler; John D Shaughnessy; Bart Barlogie; Frits van Rhee; Mohamad Hussein; Daniel E H Afar; Marna B Williams
CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(9):2775-84.
2008: Shmuel Yaccoby; A Pennisi; X Li; S R Dillon; Fenghuang Zhan; Bart Barlogie; John D Shaughnessy
Atacicept (TACI-Ig) inhibits growth of TACI(high) primary myeloma cells in SCID-hu mice and in coculture with osteoclasts.
Leukemia 2008;22(2):406-13.
2008: Fenghuang Zhan; Bart Barlogie; George Mulligan; John D Shaughnessy; Bryant Barbara
High-risk myeloma: a gene expression based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed disease treated with single-agent bortezomib or high-dose dexamethasone.
Blood 2008;111(2):968-9.
2008: Unn-Merete Fagerli; Randi Utne Holt; Toril Holien; Thea K Vaatsveen; Fenghuang Zhan; Kjartan Wollo Egeberg; Bart Barlogie; Anders Waage; Harald Aarset; Hong Yan Dai; John D Shaughnessy; Anders Sundan; Magne Børset
Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells.
Blood 2008;111(2):806-15.
2007: Jeffrey Haessler; John D Shaughnessy; Fenghuang Zhan; John Crowley; Joshua Epstein; Frits van Rhee; Elias Anaissie; Mauricio Pineda-Roman; Maurizio Zangari; Klaus Hollmig; Abid Mohiuddin; Yazan Alsayed; Antje Hoering; Guido Tricot; Bart Barlogie
Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7073-9.
2007: Susann M Szmania; Sacha Gnjatic; Guido Tricot; Katie Stone; Fenghuang Zhan; Amberly Moreno; Brad Thuro; J Joseph Melenhorst; John Barrett; John Shaughnessy; Lloyd J Old; Bart Barlogie; Vincent G Brichard; Frits van Rhee
Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(8):847-54.
2007: H Keshava Prasad; Fenghuang Zhan; John Shaughnessy
Smoldering multiple myeloma.
The New England journal of medicine 2007;357(10):1048; author reply 1049-50.
2007: Xin Li; Angela Pennisi; Fenghuang Zhan; Jeffrey R Sawyer; John D Shaughnessy; Shmuel Yaccoby
Establishment and exploitation of hyperdiploid and non-hyperdiploid human myeloma cell lines.
British journal of haematology 2007;138(6):802-11.
2007: Jianfei Qian; Jin Xie; Sungyoul Hong; Jing Yang; Liang Zhang; Xiaohong Han; Michael Wang; Fenghuang Zhan; John D Shaughnessy; Joshua Epstein; Larry W Kwak; Qing Yi
Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma.
Blood 2007;110(5):1587-94.
2007: Christina Annunziata; R Eric Davis; Yulia Demchenko; William Bellamy; Ana Gabrea; Fenghuang Zhan; Georg Lenz; Ichiro Hanamura; George Wright; Wenming Xiao; Sandeep Dave; Elaine M Hurt; Bruce Tan; Hong Zhao; Owen Stephens; Madhumita Santra; David R Williams; Lenny Dang; Bart Barlogie; John D Shaughnessy; W Michael Kuehl; Louis M Staudt
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.
Cancer cell 2007;12(2):115-30.
2007: Fenghuang Zhan; Simona Colla; Xiaosong Wu; Bangzheng Chen; James P Stewart; W Michael Kuehl; Bart Barlogie; John D Shaughnessy
CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
Blood 2007;109(11):4995-5001.
2007: Simona Colla; Fenghuang Zhan; Wei Xiong; Xiaosong Wu; Hongwei Xu; Owen Stephens; Shmuel Yaccoby; Joshua Epstein; Bart Barlogie; John D Shaughnessy
The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells.
Blood 2007;109(10):4470-7.
2007: Yang Yang; Veronica MacLeod; Hua-Quan Miao; Allison Theus; Fenghuang Zhan; John D Shaughnessy; Jeffrey Sawyer; Jin-Ping Li; Eyal Zcharia; Israel Vlodavsky; Ralph D Sanderson
Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis.
The Journal of biological chemistry 2007;282(18):13326-33.
2007: Jaime O Claudio; Fenghuang Zhan; L Zhuang; R Khaja; Yuan Xiao Zhu; K Sivananthan; Suzanne Trudel; Esther Masih-Khan; Rafael Fonseca; P Leif Bergsagel; S W Scherer; John Shaughnessy; A Keith Stewart
Expression and mutation status of candidate kinases in multiple myeloma.
Leukemia 2007;21(5):1124-7.
2007: George Mulligan; Constantine S Mitsiades; Bryant Barbara; Fenghuang Zhan; Wee J Chng; Steven Roels; Erik Koenig; Andrew Fergus; Yongsheng Huang; Paul G Richardson; William L Trepicchio; Annemiek Broyl; Pieter Sonneveld; John D Shaughnessy; P Leif Bergsagel; David P Schenkein; Dixie Esseltine; Anthony Boral; Kenneth C Anderson
Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib.
Blood 2007;109(8):3177-88.
2007: Fenghuang Zhan; Bart Barlogie; Shaughnessy John D
Gene expression profiling defines a high-risk entity of multiple myeloma.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2007;32(2):191-203.
2007: John D Shaughnessy; Fenghuang Zhan; Bart E Burington; Yongsheng Huang; Simona Colla; Ichiro Hanamura; James P Stewart; Bob Kordsmeier; Christopher Randolph; David R Williams; Yan Xiao; Hongwei Xu; Joshua Epstein; Elias Anaissie; Somashekar G Krishna; Michele Cottler-Fox; Klaus Hollmig; Abid Mohiuddin; Mauricio Pineda-Roman; Guido Tricot; Frits van Rhee; Jeffrey Sawyer; Yazan Alsayed; Ronald Walker; Maurizio Zangari; John Crowley; Bart Barlogie
A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.
Blood 2007;109(6):2276-84.
2007: Shmuel Yaccoby; Wen Ling; Fenghuang Zhan; Ronald Walker; Bart Barlogie; John D Shaughnessy
Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo.
Blood 2007;109(5):2106-11.
2007: Fenghuang Zhan; Bart Barlogie; Varant Arzoumanian; Yongsheng Huang; David R Williams; Klaus Hollmig; Mauricio Pineda-Roman; Guido Tricot; Frits van Rhee; Maurizio Zangari; Madhav V Dhodapkar; John D Shaughnessy
Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis.
Blood 2007;109(4):1692-700.
2007: Eun Sung Park; John D Shaughnessy; Shalu Gupta; Hongyang Wang; Ju Seog Lee; hyun goo woo; Fenghuang Zhan; James D Owens; Michael Potter; Siegfried Janz; J Frederic Mushinski
Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c-Myc in a model of plasma cell neoplasia.
BMC genomics 2007;8():302.
2007: Eun Sung Park; Ju Seog Lee; hyun goo woo; Fenghuang Zhan; Joanna H Shih; John D Shaughnessy; J Frederic Mushinski
Heterologous tissue culture expression signature predicts human breast cancer prognosis.
PloS one 2007;2(1):e145.
2006: Fenghuang Zhan; Yongsheng Huang; Simona Colla; James P Stewart; Ichiro Hanamura; Sushil Gupta; Joshua Epstein; Shmuel Yaccoby; Jeffrey Sawyer; Bart E Burington; Elias Anaissie; Klaus Hollmig; Mauricio Pineda-Roman; Guido Tricot; Frits van Rhee; Ronald Walker; Maurizio Zangari; John Crowley; Bart Barlogie; John D Shaughnessy
The molecular classification of multiple myeloma.
Blood 2006;108(6):2020-8.
2006: Vladimir Lazarevic; Ake Wahlin; Magnus Hultdin; Fenghuang Zhan; John Shaughnessy
Chronic lymphocytic leukemia with osteolytic Richter's syndrome mimicking myeloma bone disease shows no over-expression of DKK1.
Leukemia & lymphoma 2006;47(9):1987-8.
2006: Fenghuang Zhan; J Sawyer; Guido Tricot
The role of cytogenetics in myeloma.
Leukemia 2006;20(9):1484-6.
2006: Ichiro Hanamura; James P Stewart; Yongsheng Huang; Fenghuang Zhan; Madhumita Santra; Jeffrey R Sawyer; Klaus Hollmig; Maurizio Zangarri; Mauricio Pineda-Roman; Frits van Rhee; Federica Cavallo; Bart E Burington; John Crowley; Guido Tricot; Bart Barlogie; John D Shaughnessy
Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation.
Blood 2006;108(5):1724-32.
2006: Ichiro Hanamura; Y Huang; Fenghuang Zhan; Bart Barlogie; John Shaughnessy
Prognostic value of cyclin D2 mRNA expression in newly diagnosed multiple myeloma treated with high-dose chemotherapy and tandem autologous stem cell transplantations.
Leukemia 2006;20(7):1288-90.
2006: Daniel R Carrasco; Giovanni Tonon; Yongsheng Huang; Yunyu Zhang; Raktim Sinha; Bin Feng; James P Stewart; Fenghuang Zhan; Deepak Khatry; Marina Protopopova; Alexei Protopopov; Kumar Sukhdeo; Ichiro Hanamura; Owen Stephens; Bart Barlogie; Kenneth C Anderson; Lynda Chin; John D Shaughnessy; Cameron Brennan; Ronald A DePinho
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients.
Cancer cell 2006;9(4):313-25.
2006: Yun Ge; Fenghuang Zhan; Bart Barlogie; Joshua Epstein; John Shaughnessy; Shmuel Yaccoby
Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival.
British journal of haematology 2006;133(1):83-92.
2006: Amel Dib; Timothy R Peterson; Laura Raducha-Grace; Adriana Zingone; Fenghuang Zhan; Ichiro Hanamura; Bart Barlogie; John Shaughnessy; W Michael Kuehl
Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression.
Cell division 2006;1():23.
2005: Atsushi Suzuki; Shinsuke Iida; Miyuki Kato-Uranishi; Emi Tajima; Fenghuang Zhan; Ichiro Hanamura; Yongsheng Huang; Tsutomu Ogura; Satoru Takahashi; Ryuzo Ueda; Bart Barlogie; John Shaughnessy; Hiroyasu Esumi
ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma.
Oncogene 2005;24(46):6936-44.
2005: P Leif Bergsagel; W Michael Kuehl; Fenghuang Zhan; Jeffrey Sawyer; Bart Barlogie; John Shaughnessy
Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma.
Blood 2005;106(1):296-303.
2005: Frits van Rhee; Susann M Szmania; Fenghuang Zhan; Sushil K Gupta; Mindy Pomtree; Pei Lin; Ramesh Babu Batchu; Amberly Moreno; Guilio Spagnoli; John Shaughnessy; Guido Tricot
NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses.
Blood 2005;105(10):3939-44.
2005: Alessandro D Santin; Fenghuang Zhan; Stefania Cane'; Stefania Bellone; Michela Palmieri; M Thomas; Alexander Burnett; Juan J Roman; Martin J Cannon; John Shaughnessy; Sergio Pecorelli
Gene expression fingerprint of uterine serous papillary carcinoma: identification of novel molecular markers for uterine serous cancer diagnosis and therapy.
British journal of cancer 2005;92(8):1561-73.
2005: Alessandro D Santin; Fenghuang Zhan; Eliana Bignotti; Eric Siegel; Stefania Cané; Stefania Bellone; Michela Palmieri; Simone Anfossi; Maria Thomas; Alexander Burnett; Helen H Kay; Juan J Roman; Timothy J O'Brien; Erming Tian; Martin J Cannon; John Shaughnessy; Sergio Pecorelli
Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy.
Virology 2005;331(2):269-91.
2005: John Shaughnessy; Fenghuang Zhan; Bart Barlogie; A K Stewart
Gene expression profiling and multiple myeloma.
Best practice & research. Clinical haematology 2005;18(4):537-52.
2004: Alessandro D Santin; Fenghuang Zhan; Stefania Bellone; Michela Palmieri; Stefania Cane; Eliana Bignotti; Simone Anfossi; Murat Gokden; Donna Dunn; Juan J Roman; Timothy J O'Brien; Erming Tian; Martin J Cannon; John Shaughnessy; Sergio Pecorelli
Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy.
International journal of cancer. Journal international du cancer 2004;112(1):14-25.
2004: Pei Lin; Mustafa Mahdavy; Fenghuang Zhan; Hua-Zhong Zhang; Ruth Katz; John D Shaughnessy
Expression of PAX5 in CD20-positive multiple myeloma assessed by immunohistochemistry and oligonucleotide microarray.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(10):1217-22.
2004: Christopher A Maxwell; Erik Rasmussen; Fenghuang Zhan; Jonathan J Keats; Sophia Adamia; Erin Strachan; Mary Crainie; Ronald Walker; Andrew R Belch; Linda M Pilarski; Bart Barlogie; John Shaughnessy; Tony Reiman
RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.
Blood 2004;104(4):1151-8.
2004: Alessandro D Santin; Fenghuang Zhan; Stefania Bellone; Michela Palmieri; Stefania Cane; Murat Gokden; Juan J Roman; Timothy J O'Brien; Erming Tian; Martin J Cannon; John Shaughnessy; Sergio Pecorelli
Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling.
British journal of cancer 2004;90(9):1814-24.
2004: Johanna Hardin; Michael Waddell; C David Page; Fenghuang Zhan; Bart Barlogie; John Shaughnessy; John J Crowley
Evaluation of multiple models to distinguish closely related forms of disease using DNA microarray data: an application to multiple myeloma.
Statistical applications in genetics and molecular biology 2004;3():Article10.
2003: Erming Tian; Fenghuang Zhan; Ronald Walker; Erik Rasmussen; Yupo Ma; Bart Barlogie; John D Shaughnessy
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma.
The New England journal of medicine 2003;349(26):2483-94.
2003: Thomas Kelly; Hua-Quan Miao; Yang Yang; Elizabeth Navarro; Paul Kussie; Yan Huang; Veronica MacLeod; Jonathan Casciano; Lija Joseph; Fenghuang Zhan; Maurizio Zangari; Bart Barlogie; John Shaughnessy; Ralph D Sanderson
High heparanase activity in multiple myeloma is associated with elevated microvessel density.
Cancer research 2003;63(24):8749-56.
2003: Fenghuang Zhan; Bart Barlogie; John Shaughnessy
Toward the identification of distinct molecular and clinical entities of multiple myeloma using global gene expression profiling.
Seminars in hematology 2003;40(4):308-20.
2003: Ramesh Babu Batchu; A M Moreno; Susann M Szmania; S K Gupta; Fenghuang Zhan; Nancy Rosen; M Kozlowski; Horace Spencer; G C Spagnoli; John Shaughnessy; Bart Barlogie; Guido Tricot; Frits van Rhee
High-level expression of cancer/testis antigen NY-ESO-1 and human granulocyte-macrophage colony-stimulating factor in dendritic cells with a bicistronic retroviral vector.
Human gene therapy 2003;14(14):1333-45.
2003: Clive S Zent; Fenghuang Zhan; Steven A Schichman; Klaus Bumm; Pei Lin; James B Chen; John D Shaughnessy
The distinct gene expression profiles of chronic lymphocytic leukemia and multiple myeloma suggest different anti-apoptotic mechanisms but predict only some differences in phenotype.
Leukemia research 2003;27(9):765-74.
2003: Karin Tarte; Fenghuang Zhan; John De Vos; Bernard Klein; John Shaughnessy
Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation.
Blood 2003;102(2):592-600.
2003: John Shaughnessy; Joth Jacobson; Jeffrey Sawyer; Jason McCoy; AB Fassas; Fenghuang Zhan; Klaus Bumm; Joshua Epstein; Elias Anaissie; Sundar Jagannath; David H Vesole; David Siegel; Raman Desikan; Nikhil Munshi; Ashraf Badros; Erming Tian; Maurizio Zangari; Guido Tricot; John Crowley; Bart Barlogie
Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression.
Blood 2003;101(10):3849-56.
2003: Jeroen Guikema; Sjoerd Hovenga; Edo Vellenga; Jelle J Conradie; Wayel Habib Abdulahad; Roelof Bekkema; Jan W Smit; Fenghuang Zhan; John Shaughnessy; Nicolaas A Bos
CD27 is heterogeneously expressed in multiple myeloma: low CD27 expression in patients with high-risk disease.
British journal of haematology 2003;121(1):36-43.
2003: Madhumita Santra; Fenghuang Zhan; Erming Tian; Bart Barlogie; John Shaughnessy
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript.
Blood 2003;101(6):2374-6.
2003: Fenghuang Zhan; Erming Tian; Klaus Bumm; Ruston Smith; Bart Barlogie; John Shaughnessy
Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development.
Blood 2003;101(3):1128-40.
2002: Adel K El-Naggar; Hyung W Kim; Gary L Clayman; Madelene M Coombes; Bao Le; Syeling Lai; Fenghuang Zhan; Mario A Luna; Waun Ki Hong; J Jack Lee
Differential expression profiling of head and neck squamous carcinoma: significance in their phenotypic and biological classification.
Oncogene 2002;21(53):8206-19.
2002: Karin Tarte; John De Vos; Thomas Thykjaer; Fenghuang Zhan; Geneviève Fiol; Valérie Costes; Thierry Rème; Eric Legouffe; Jean-François Rossi; John Shaughnessy; Torben F Ørntoft; Bernard Klein
Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts.
Blood 2002;100(4):1113-22.
2002: Omar Eton; Sewa S Legha; Agop Bedikian; J Jack Lee; Antonio C Buzaid; Cynthia Hodges; Sigrid E Ring; Nicholas E Papadopoulos; Carl Plager; Mary Jo East; Fenghuang Zhan; Robert S Benjamin
Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(8):2045-52.
2002: Fenghuang Zhan; Johanna Hardin; Bob Kordsmeier; Klaus Bumm; Mingzhong Zheng; Erming Tian; Ralph D Sanderson; Yang Yang; Carla Wilson; Maurizio Zangari; Elias Anaissie; Christopher Morris; Firas Muwalla; Frits van Rhee; AB Fassas; John Crowley; Guido Tricot; Bart Barlogie; John Shaughnessy
Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells.
Blood 2002;99(5):1745-57.
2002: Hong-Ran Choi; John G Batsakis; Fenghuang Zhan; Erich M Sturgis; Mario A Luna; Adel K El-Naggar
Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis.
Human pathology 2002;33(2):158-64.
2002: Klaus Bumm; Mingzhong Zheng; Clyde Bailey; Fenghuang Zhan; Maurizio Chiriva-Internati; Paul Eddlemon; Julian Terry; Bart Barlogie; John D Shaughnessy
CGO: utilizing and integrating gene expression microarray data in clinical research and data management.
Bioinformatics (Oxford, England) 2002;18(2):327-8.
2001: John Shaughnessy; Ana Gabrea; Y Qi; Leslie A Brents; Fenghuang Zhan; Erming Tian; Jeffrey Sawyer; Bart Barlogie; P Leif Bergsagel; M Kuehl
Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma.
Blood 2001;98(1):217-23.
2000: N Jiang; Fenghuang Zhan; L Cao; K Yao; G Li
c-myc gene inactivation during induction of nasopharyngeal carcinoma cells with retinoic acid.
Chinese medical journal 2000;113(9):823-6.
2000: Y Xie; LW Deng; N Jiang; Fenghuang Zhan; L Cao; Y Qiu; X Tang; G Li
[Molecular cloning of a novel gene located on chromosome 3p25.3 and an analysis of its expression in nasopharyngeal carcinoma].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2000;17(4):225-8.
2000: N Jiang; Fenghuang Zhan; G Tan; LW Deng; M Zhou; L Cao; Y Qiu; Y Xie; G Li
A cDNA located on chromosome 7q32 shows loss of expression in epithelial cell line of nasopharyngeal carcinoma.
Chinese medical journal 2000;113(7):650-3.
1999: L Bin; C Hu; Fenghuang Zhan
[The expression in situ of transforming growth factor beta s, their receptors and TGF beta-receptor interacting protein-1 in nasopharygneal carcinoma].
Zhonghua er bi yan hou ke za zhi 1999;34(4):210-2.
1999: Fenghuang Zhan; L Cao; L Bin; N Jiang; LW Deng; Y Xie; G Tan; G Li
cDNA representational difference analysis of differentially expressed cDNA sequences in human nasopharyngeal carcinoma.
Chinese medical journal 1999;112(6):538-42.
1999: Fenghuang Zhan; L Cao; C Hu; G Li
[Differentially expressed cDNA sequences homologous with known genes in human nasopharyngeal carcinoma].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 1999;24(2):103-6.
1999: N Jiang; LW Deng; G L Tan; Fenghuang Zhan; M Zhou; L Cao; Y Z Qiu; Y Xie; G Y Li
[A nasopharyngeal carcinoma negatively related EST on 7q32].
Yi chuan xue bao = Acta genetica Sinica 1999;26(4):301-8.
1998: Fenghuang Zhan; N Jiang; L Cao; LW Deng; G Tan; M Zhou; Y Xie; G Li
[Primary study of differentially expressed cDNA sequences in cell line HNE1 of human nasopharyngeal carcinoma by cDNA representational difference analysis].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 1998;15(6):341-4.
1998: N Jiang; Fenghuang Zhan; Y Xie; Z Zeng; M Zhou; LW Deng; G Li
[Establishment of partial gene expression map of 7q32 in nasopharyngeal carcinoma and primary culture normal nasopharyngeal epithelial cells].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 1998;15(5):267-70.
1998: LW Deng; N Jing; G Tan; M Zhou; Fenghuang Zhan; Y Xie; L Cao; G Li
A common region of allelic loss on chromosome region 3p25.3-26.3 in nasopharyngeal carcinoma.
Genes, chromosomes & cancer 1998;23(1):21-5.
1997: Fenghuang Zhan; X C Jian; Z H Shen
Giant hemangioma of the sternocleidomastoid muscle: report of a case.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 1997;55(2):190-3.