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Wes Trotter

Research Profile

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Chemicals & Drugs

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Bacteriophage T7

Physiology

Protein Prenylation

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Publications

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Wes Trotter; Kausik K Nanda; Nathan R Kett; christopher regan; Joseph J Lynch; Gary L Stump; Laszlo Kiss; Jixin Wang; Robert H Spencer; Stefanie A Kane; Rebecca B White; Rena Zhang; Kenneth D Anderson; Nigel J Liverton; Charles J McIntyre; Douglas C Beshore; George D Hartman; Christopher Dinsmore
Design and synthesis of novel isoquinoline-3-nitriles as orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillation.
Kausik K Nanda; M Brad Nolt; Matthew J Cato; Stefanie A Kane; Laszlo Kiss; Robert H Spencer; Jixin Wang; Joseph J Lynch; christopher regan; Gary L Stump; Bing Li; Rebecca White; Suzie Yeh; Michael J Bogusky; Mark T Bilodeau; Christopher Dinsmore; Craig W Lindsley; George D Hartman; Scott E Wolkenberg; Wes Trotter
Potent antagonists of the Kv1.5 potassium channel: synthesis and evaluation of analogous N,N-diisopropyl-2-(pyridine-3-yl)acetamides.
Ian M Bell; Steven M Stirdivant; Janet Ahern; J Christopher Culberson; Paul L Darke; Christopher Dinsmore; Robert A Drakas; Steven N Gallicchio; Samuel L Graham; David C Heimbrook; Dawn L Hall; Jin Hua; Nathan R Kett; Annette S Kim; Maria Kornienko; Lawrence C Kuo; Sanjeev Munshi; Amy G Quigley; John C Reid; Wes Trotter; Lloyd H Waxman; Theresa M Williams; C Blair Zartman
Biochemical and structural characterization of a novel class of inhibitors of the type 1 insulin-like growth factor and insulin receptor kinases.

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All Publications

2006: Wes Trotter; Kausik K Nanda; Nathan R Kett; christopher regan; Joseph J Lynch; Gary L Stump; Laszlo Kiss; Jixin Wang; Robert H Spencer; Stefanie A Kane; Rebecca B White; Rena Zhang; Kenneth D Anderson; Nigel J Liverton; Charles J McIntyre; Douglas C Beshore; George D Hartman; Christopher Dinsmore
Design and synthesis of novel isoquinoline-3-nitriles as orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillation.
Journal of medicinal chemistry 2006;49(24):6954-7.
2006: Kausik K Nanda; M Brad Nolt; Matthew J Cato; Stefanie A Kane; Laszlo Kiss; Robert H Spencer; Jixin Wang; Joseph J Lynch; christopher regan; Gary L Stump; Bing Li; Rebecca White; Suzie Yeh; Michael J Bogusky; Mark T Bilodeau; Christopher Dinsmore; Craig W Lindsley; George D Hartman; Scott E Wolkenberg; Wes Trotter
Potent antagonists of the Kv1.5 potassium channel: synthesis and evaluation of analogous N,N-diisopropyl-2-(pyridine-3-yl)acetamides.
Bioorganic & medicinal chemistry letters 2006;16(22):5897-901.
2005: Ian M Bell; Steven M Stirdivant; Janet Ahern; J Christopher Culberson; Paul L Darke; Christopher Dinsmore; Robert A Drakas; Steven N Gallicchio; Samuel L Graham; David C Heimbrook; Dawn L Hall; Jin Hua; Nathan R Kett; Annette S Kim; Maria Kornienko; Lawrence C Kuo; Sanjeev Munshi; Amy G Quigley; John C Reid; Wes Trotter; Lloyd H Waxman; Theresa M Williams; C Blair Zartman
Biochemical and structural characterization of a novel class of inhibitors of the type 1 insulin-like growth factor and insulin receptor kinases.
Biochemistry 2005;44(27):9430-40.
2001: Wes Trotter; Amy G Quigley; William C Lumma; John T Sisko; Eileen S Walsh; C S Hamann; Ronald G Robinson; HG Bhimnathwala; D G Kolodin; W Zheng; Carolyn A Buser; Hans E Huber; Robert B Lobell; Nancy E Kohl; Theresa M Williams; Samuel L Graham; Christopher Dinsmore
2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase.
Bioorganic & medicinal chemistry letters 2001;11(7):865-9.
1999: Rosa Zerella; P A Evans; J M Ionides; Len C Packman; Wes Trotter; Joel Mackay; Dudley H Williams
Autonomous folding of a peptide corresponding to the N-terminal beta-hairpin from ubiquitin.
Protein science : a publication of the Protein Society 1999;8(6):1320-31.
1992: N A Van Draanen; S C Tucker; F L Boyd; Wes Trotter; J E Reardon
Beta-L-thymidine 5'-triphosphate analogs as DNA polymerase substrates.
The Journal of biological chemistry 1992;267(35):25019-24.