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Weijing Cai

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TOP 3
Weijing Cai; Xue Chen; Maya Ramdas; Gary E Striker; Li Zhu; Helen Vlassara
Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1.
Helen Vlassara; Mark Woodward; Jaime Uribarri; Weijing Cai; Susan Goodman; Fabrizio Grosjean; James Post; Renata Pyzik; Gary E Striker
Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease.
Jaime Uribarri; Li Zhu; Weijing Cai; Xue Chen; Susan Goodman; Renata Pyzik; Maya Ramdas; Gary E Striker; Helen Vlassara
Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: potential role of AGER1 and SIRT1.

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All Publications

2012: Weijing Cai; Xue Chen; Maya Ramdas; Gary E Striker; Li Zhu; Helen Vlassara
Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(39):15888-93.
2012: Helen Vlassara; Mark Woodward; Jaime Uribarri; Weijing Cai; Susan Goodman; Fabrizio Grosjean; James Post; Renata Pyzik; Gary E Striker
Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease.
Clinical journal of the American Society of Nephrology : CJASN 2012;7(6):934-42.
2011: Jaime Uribarri; Li Zhu; Weijing Cai; Xue Chen; Susan Goodman; Renata Pyzik; Maya Ramdas; Gary E Striker; Helen Vlassara
Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: potential role of AGER1 and SIRT1.
Diabetes care 2011;34(7):1610-6.
2010: Jaime Uribarri; Sandra Woodruff; Susan Goodman; Weijing Cai; Xue Chen; Renata Pyzik; Angie Yong; Gary E Striker; Helen Vlassara
Advanced glycation end products in foods and a practical guide to their reduction in the diet.
Journal of the American Dietetic Association 2010;110(6):911-16.e12.
2010: Weijing Cai; Massimo Torreggiani; Li Zhu; Xue Chen; John Cijiang He; Gary E Striker; Helen Vlassara
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.
American journal of physiology. Cell physiology 2010;298(3):C624-34.
2009: Helen Vlassara; Jaime Uribarri; Luigi Ferrucci; Weijing Cai; Massimo Torreggiani; James B Post; Feng Zheng; Gary E Striker
Identifying advanced glycation end products as a major source of oxidants in aging: implications for the management and/or prevention of reduced renal function in elderly persons.
Seminars in nephrology 2009;29(6):594-603.
2009: Helen Vlassara; Weijing Cai; Susan Goodman; Renata Pyzik; Angie Yong; Xue Chen; Li Zhu; Tina Neade; Michal Beeri; Jeremy M Silverman; Luigi Ferrucci; Laurie Tansman; Gary E Striker; Jaime Uribarri
Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1.
The Journal of clinical endocrinology and metabolism 2009;94(11):4483-91.
2009: Massimo Torreggiani; Huixian Liu; Jin Wu; Feng Zheng; Weijing Cai; Gary Striker; Helen Vlassara
Advanced glycation end product receptor-1 transgenic mice are resistant to inflammation, oxidative stress, and post-injury intimal hyperplasia.
The American journal of pathology 2009;175(4):1722-32.
2009: Zhengshan Zhao; Chunying Zhao; Xu Hannah Zhang; Feng Zheng; Weijing Cai; Helen Vlassara; Zhongmin Alex Ma
Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis.
Endocrinology 2009;150(6):2569-76.
2008: Weijing Cai; John Cijiang He; Li Zhu; Xue Chen; Feng Zheng; Gary E Striker; Helen Vlassara
Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan.
The American journal of pathology 2008;173(2):327-36.
2008: Ellena Linden; Weijing Cai; John Cijiang He; Chen Xue; Zhu Li; Jonathan Winston; Helen Vlassara; Jaime Uribarri
Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation.
Clinical journal of the American Society of Nephrology : CJASN 2008;3(3):691-8.
2008: Helen Vlassara; Jaime Uribarri; Weijing Cai; Gary E Striker
Advanced glycation end product homeostasis: exogenous oxidants and innate defenses.
Annals of the New York Academy of Sciences 2008;1126():46-52.
2008: Weijing Cai; John Cijiang He; Li Zhu; Xue Chen; Gary E Striker; Helen Vlassara
AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.
American journal of physiology. Cell physiology 2008;294(1):C145-52.
2007: Jaime Uribarri; Alin Stirban; Denise Sander; Weijing Cai; Monica Negrean; Cristina E Buenting; Theodor Koschinsky; Helen Vlassara
Single oral challenge by advanced glycation end products acutely impairs endothelial function in diabetic and nondiabetic subjects.
Diabetes care 2007;30(10):2579-82.
2007: Weijing Cai; John Cijiang He; Li Zhu; Xue Chen; Sylvan Wallenstein; Gary E Striker; Helen Vlassara
Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression.
The American journal of pathology 2007;170(6):1893-902.
2007: Jaime Uribarri; Weijing Cai; Melpomeni Peppa; Susan Goodman; Luigi Ferrucci; Gary E Striker; Helen Vlassara
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(4):427-33.
2006: Weijing Cai; John Cijiang He; Li Zhu; Changyong Lu; Helen Vlassara
Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(37):13801-6.
2006: Melpomeni Peppa; Harold Brem; Weijing Cai; Jiang-Gang Zhang; John Basgen; Zhu Li; Helen Vlassara; Jaime Uribarri
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711).
American journal of nephrology 2006;26(5):430-6.
2006: Weijing Cai; Li Zhu; Xue Chen; Jaime Uribarri; Melpomeni Peppa
Association of advanced glycoxidation end products and inflammation markers with thrombosis of arteriovenous grafts in hemodialysis patients.
American journal of nephrology 2006;26(2):181-5.
2005: Oana Sandu; Keying Song; Weijing Cai; Feng Zheng; Jaime Uribarri; Helen Vlassara
Insulin resistance and type 2 diabetes in high-fat-fed mice are linked to high glycotoxin intake.
Diabetes 2005;54(8):2314-9.
2005: Jaime Uribarri; Weijing Cai; Oana Sandu; Melpomeni Peppa; Teresia Goldberg; Helen Vlassara
Diet-derived advanced glycation end products are major contributors to the body's AGE pool and induce inflammation in healthy subjects.
Annals of the New York Academy of Sciences 2005;1043():461-6.
2004: Changyong Lu; John Cijiang He; Weijing Cai; Huixian Liu; Li Zhu; Helen Vlassara
Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11767-72.
2004: Teresia Goldberg; Weijing Cai; Melpomeni Peppa; Veronique Dardaine; Bantwal Suresh Baliga; Jaime Uribarri; Helen Vlassara
Advanced glycoxidation end products in commonly consumed foods.
Journal of the American Dietetic Association 2004;104(8):1287-91.
2004: Weijing Cai; John Cijiang He; Li Zhu; Melpomeni Peppa; Changyong Lu; Jaime Uribarri; Helen Vlassara
High levels of dietary advanced glycation end products transform low-density lipoprotein into a potent redox-sensitive mitogen-activated protein kinase stimulant in diabetic patients.
Circulation 2004;110(3):285-91.
2004: Melpomeni Peppa; Jaime Uribarri; Weijing Cai; Min Lu; Helen Vlassara
Glycoxidation and inflammation in renal failure patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2004;43(4):690-5.
2003: Melpomeni Peppa; Harold Brem; Paul Ehrlich; Jian-Gang Zhang; Weijing Cai; Zhu Li; Anca Croitoru; Swan N Thung; Helen Vlassara
Adverse effects of dietary glycotoxins on wound healing in genetically diabetic mice.
Diabetes 2003;52(11):2805-13.
2003: Jaime Uribarri; Melpomeni Peppa; Weijing Cai; Teresia Goldberg; Min Lu; Suresh Baliga; Joseph A Vassalotti; Helen Vlassara
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2003;42(3):532-8.
2003: Reigh-Yi Lin; Robin P Choudhury; Weijing Cai; Min Lu; John T Fallon; Edward A Fisher; Helen Vlassara
Dietary glycotoxins promote diabetic atherosclerosis in apolipoprotein E-deficient mice.
Atherosclerosis 2003;168(2):213-20.
2003: Jaime Uribarri; Melpomeni Peppa; Weijing Cai; Teresia Goldberg; Min Lu; Cijiang He; Helen Vlassara
Restriction of dietary glycotoxins reduces excessive advanced glycation end products in renal failure patients.
Journal of the American Society of Nephrology : JASN 2003;14(3):728-31.
2002: Helen Vlassara; Weijing Cai; Jill Crandall; Teresia Goldberg; Robert Oberstein; Veronique Dardaine; Melpomeni Peppa; Elliot J Rayfield
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15596-601.
2002: Melpomeni Peppa; Teresia Goldberg; Weijing Cai; Elliot Rayfield; Helen Vlassara
Glycotoxins: a missing link in the "relationship of dietary fat and meat intake in relation to risk of type 2 diabetes in men".
Diabetes care 2002;25(10):1898-9.
2002: Weijing Cai; Qiao-Di Gao; Li Zhu; Melpomeni Peppa; Cijiang He; Helen Vlassara
Oxidative stress-inducing carbonyl compounds from common foods: novel mediators of cellular dysfunction.
Molecular medicine (Cambridge, Mass.) 2002;8(7):337-46.
2002: Susanna M Hofmann; Heng-Jiang Dong; Zhu Li; Weijing Cai; Jennifer Altomonte; Swan N Thung; Feng Zeng; Edward A Fisher; Helen Vlassara
Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse.
Diabetes 2002;51(7):2082-9.
2001: Feng Zheng; Weijing Cai; T Mitsuhashi; Helen Vlassara
Lysozyme enhances renal excretion of advanced glycation endproducts in vivo and suppresses adverse age-mediated cellular effects in vitro: a potential AGE sequestration therapy for diabetic nephropathy?
Molecular medicine (Cambridge, Mass.) 2001;7(11):737-47.