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Senena Corbalan-Garcia
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44
Gómez-Fernández, Juan
17
Torrecillas, Alejandro
8
de Godos, Ana
6
Marín-Vicente, Consuelo
5
Gomez-Fernandez, Juan
5
Sánchez-Bautista, Sonia
5
Ausili, Alessio
5
Conesa-Zamora, Pablo
4
Fita, Ignacio
4
Bar-Sagi, Dafna
4
Rodríguez-Alfaro, José
3
Ochoa, Wendy
3
Verdaguer, Nuria
3
Mollinedo, Faustino
3
Aranda, Francisco
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All Publications
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2009: Ausili Alessio; de Godos Ana; Torrecillas Alejandro; Corbalán-García Senena; Gómez-Fernández Juan C
The interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids.
Biochimica et biophysica acta 2009;1788(9):1924-32.
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2009: Sánchez-Bautista Sonia; Corbalán-García Senena; Pérez-Lara Angel; Gómez-Fernández Juan C
A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.
Biophysical journal 2009;96(9):3638-47.
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2009: Guerrero-Valero Marta; Ferrer-Orta Cristina; Querol-Audí Jordi; Marin-Vicente Consuelo; Fita Ignacio; Gómez-Fernández Juan C; Verdaguer Nuria; Corbalán-García Senena
Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(16):6603-7.
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2008: Ausili Alessio; Torrecillas Alejandro; Aranda Francisco; de Godos Ana; Sánchez-Bautista Sonia; Corbalán-García Senena; Gómez-Fernández Juan C
Redox state of coenzyme Q10 determines its membrane localization.
The journal of physical chemistry. B 2008;112(40):12696-702.
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2008: Ausili Alessio; Torrecillas Alejandro; Martínez-Senac María M; Corbalán-García Senena; Gómez-Fernández Juan C
The interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes.
Journal of structural biology 2008;164(1):146-52.
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2008: Ausili Alessio; Torrecillas Alejandro; Aranda Francisco J; Mollinedo Faustino; Gajate Consuelo; Corbalán-García Senena; de Godos Ana; Gómez-Fernández Juan C
Edelfosine is incorporated into rafts and alters their organization.
The journal of physical chemistry. B 2008;112(37):11643-54.
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2008: Marín-Vicente Consuelo; Nicolás Francisco E; Gómez-Fernández Juan C; Corbalán-García Senena
The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells.
Journal of molecular biology 2008;377(4):1038-52.
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2007: Corbalán-García S; Guerrero-Valero M; Marín-Vicente C; Gómez-Fernández J C
The C2 domains of classical/conventional PKCs are specific PtdIns(4,5)P(2)-sensing domains.
Biochemical Society transactions 2007;35(Pt 5):1046-8.
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2007: Torrecillas Alejandro; Martínez-Senac María M; Ausili Alessio; Corbalán-García Senena; Gómez-Fernández Juan C
Interaction of the C-terminal domain of Bcl-2 family proteins with model membranes.
Biochimica et biophysica acta 2007;1768(11):2931-9.
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2007: Guerrero-Valero Marta; Marín-Vicente Consuelo; Gómez-Fernández Juan C; Corbalán-García Senena
The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding.
Journal of molecular biology 2007;371(3):608-21.
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2007: Gómez-Fernández Juan C; Corbalán-García Senena
Diacylglycerols, multivalent membrane modulators.
Chemistry and physics of lipids 2007;148(1):1-25.
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2007: Sánchez-Bautista Sonia; de Godos Ana; Rodríguez-Alfaro José A; Torrecillas Alejandro; Corbalán-García Senena; Gómez-Fernández Juan C
Interaction of the C2 domain from protein kinase C(epsilon) with model membranes.
Biochemistry 2007;46(11):3183-92.
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2006: Sánchez-Bautista Sonia; Marín-Vicente Consuelo; Gómez-Fernández Juan C; Corbalán-García Senena
The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.
Journal of molecular biology 2006;362(5):901-14.
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2006: Torrecillas Alejandro; Aroca-Aguilar J Daniel; Aranda Francisco J; Gajate Consuelo; Mollinedo Faustino; Corbalán-García Senena; de Godos Ana; Gómez-Fernández Juan C
Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes.
International journal of pharmaceutics 2006;318(1-2):28-40.
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2006: Corbalán-García Senena; Gómez-Fernández Juan C
Protein kinase C regulatory domains: the art of decoding many different signals in membranes.
Biochimica et biophysica acta 2006;1761(7):633-54.
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2006: Sánchez-Bautista Sonia; Kazaks Andris; Beaulande Melanie; Torrecillas Alejandro; Corbalán-García Senena; Gómez-Fernández Juan C
Structural study of the catalytic domain of PKCzeta using infrared spectroscopy and two-dimensional infrared correlation spectroscopy.
The FEBS journal 2006;273(14):3273-86.
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2006: López-Nicolás Rubén; López-Andreo M José; Marín-Vicente Consuelo; Gómez-Fernández Juan C; Corbalán-García Senena
Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.
Journal of molecular biology 2006;357(4):1105-20.
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2005: López-Andreo María-José; Torrecillas Alejandro; Conesa-Zamora Pablo; Corbalán-García Senena; Gómez-Fernández Juan C
Retinoic acid as a modulator of the activity of protein kinase Calpha.
Biochemistry 2005;44(34):11353-60.
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2005: Torrecillas Alejandro; Martínez-Senac María M; Goormaghtigh Erik; de Godos Ana; Corbalán-García Senena; Gómez-Fernández Juan C
Modulation of the membrane orientation and secondary structure of the C-terminal domains of Bak and Bcl-2 by lipids.
Biochemistry 2005;44(32):10796-809.
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2005: Marín-Vicente Consuelo; Gómez-Fernández Juan C; Corbalán-García Senena
The ATP-dependent membrane localization of protein kinase Calpha is regulated by Ca2+ influx and phosphatidylinositol 4,5-bisphosphate in differentiated PC12 cells.
Molecular biology of the cell 2005;16(6):2848-61.
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2005: Conesa-Zamora Pablo; Mollinedo Faustino; Corbalán-García Senena; Gómez-Fernández Juan C
A comparative study of the effect of the antineoplastic ether lipid 1-O-octadecyl-2-O-methyl-glycero-3-phosphocholine and some homologous compounds on PKC alpha and PKC epsilon.
Biochimica et biophysica acta 2005;1687(1-3):110-9.
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2004: Gómez-Fernández Juan C; Torrecillas Alejandro; Corbalán-García Senena
Diacylglycerols as activators of protein kinase C.
Molecular membrane biology 2004;21(6):339-49.
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2004: Torrecillas Alejandro; Laynez José; Menéndez Margarita; Corbalán-García Senena; Gómez-Fernández Juan C
Calorimetric study of the interaction of the C2 domains of classical protein kinase C isoenzymes with Ca2+ and phospholipids.
Biochemistry 2004;43(37):11727-39.
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2004: Torrecillas Alejandro; Corbalán-García Senena; Gómez-Fernández Juan C
An infrared spectroscopic study of the secondary structure of protein kinase C alpha and its thermal denaturation.
Biochemistry 2004;43(8):2332-44.
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2004: Rodríguez-Alfaro Jose A; Gomez-Fernandez Juan C; Corbalan-Garcia Senena
Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.
Journal of molecular biology 2004;335(4):1117-29.
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2003: Jose Lopez-Andreo Maria; Gomez-Fernandez Juan C; Corbalan-Garcia Senena
The simultaneous production of phosphatidic acid and diacylglycerol is essential for the translocation of protein kinase Cepsilon to the plasma membrane in RBL-2H3 cells.
Molecular biology of the cell 2003;14(12):4885-95.
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2003: Torrecillas Alejandro; Corbalán-García Senena; Gómez-Fernández Juan C
Structural study of the C2 domains of the classical PKC isoenzymes using infrared spectroscopy and two-dimensional infrared correlation spectroscopy.
Biochemistry 2003;42(40):11669-81.
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2003: Ochoa Wendy F; Torrecillas Alejandro; Fita Ignacio; Verdaguer Nuria; Corbalán-García Senena; Gomez-Fernandez Juan C
Retinoic acid binds to the C2-domain of protein kinase C(alpha).
Biochemistry 2003;42(29):8774-9.
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2003: Bolsover Stephen R; Gomez-Fernandez Juan C; Corbalan-Garcia Senena
Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane.
The Journal of biological chemistry 2003;278(12):10282-90.
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2003: Kohout Susy C; Corbalán-García Senena; Gómez-Fernández Juan C; Falke Joseph J
C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling.
Biochemistry 2003;42(5):1254-65.
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2003: Corbalán-García Senena; García-García Josefa; Rodríguez-Alfaro José A; Gómez-Fernández Juan C
A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.
The Journal of biological chemistry 2003;278(7):4972-80.
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2002: Kohout Susy C; Corbalán-García Senena; Torrecillas Alejandro; Goméz-Fernandéz Juan C; Falke Joseph J
C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state.
Biochemistry 2002;41(38):11411-24.
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2002: Martínez-Senac María del Mar; Corbalán-García Senena; Gómez-Fernández Juan C
The structure of the C-terminal domain of the pro-apoptotic protein Bak and its interaction with model membranes.
Biophysical journal 2002;82(1 Pt 1):233-43.
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2001: Aroca J D; Sánchez-Piñera P; Corbalán-García S; Conesa-Zamora P; de Godos A; Gómez-Fernández J C
Correlation between the effect of the anti-neoplastic ether lipid 1-O-octadecyl-2-O-methyl-glycero-3-phosphocholine on the membrane and the activity of protein kinase Calpha.
European journal of biochemistry / FEBS 2001;268(24):6369-78.
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2001: Torrecillas A; Corbalán-García S; de Godos A; Gómez-Fernández J C
Activation of protein kinase C alpha by lipid mixtures containing different proportions of diacylglycerols.
Biochemistry 2001;40(49):15038-46.
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2001: Conesa-Zamora P; Lopez-Andreo M J; Gómez-Fernández J C; Corbalán-García S
Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.
Biochemistry 2001;40(46):13898-905.
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2001: Ochoa W F; Garcia-Garcia J; Fita I; Corbalan-Garcia S; Verdaguer N; Gomez-Fernandez J C
Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains.
Journal of molecular biology 2001;311(4):837-49.
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2001: del Mar Martínez-Senac M; Corbalán-García S; Gómez-Fernández J C
Conformation of the C-terminal domain of the pro-apoptotic protein Bax and mutants and its interaction with membranes.
Biochemistry 2001;40(33):9983-92.
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2001: García-García J; Gómez-Fernández J C; Corbalán-García S
Structural characterization of the C2 domain of novel protein kinase Cepsilon.
European journal of biochemistry / FEBS 2001;268(4):1107-17.
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2000: Conesa-Zamora P; Gómez-Fernández J C; Corbalán-García S
The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane.
Biochimica et biophysica acta 2000;1487(2-3):246-54.
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2000: del Mar Martínez-Senac M; Corbalán-García S; Gómez-Fernández J C
Study of the secondary structure of the C-terminal domain of the antiapoptotic protein bcl-2 and its interaction with model membranes.
Biochemistry 2000;39(26):7744-52.
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1999: Verdaguer N; Corbalan-Garcia S; Ochoa W F; Fita I; Gómez-Fernández J C
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
The EMBO journal 1999;18(22):6329-38.
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1999: García-García J; Corbalán-García S; Gómez-Fernández J C
Effect of calcium and phosphatidic acid binding on the C2 domain of PKC alpha as studied by Fourier transform infrared spectroscopy.
Biochemistry 1999;38(30):9667-75.
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1999: Corbalán-García S; Rodríguez-Alfaro J A; Gómez-Fernández J C
Determination of the calcium-binding sites of the C2 domain of protein kinase Calpha that are critical for its translocation to the plasma membrane.
The Biochemical journal 1999;337 ( Pt 3)():513-21.
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1999: Sánchez-Piñera P; Micol V; Corbalán-García S; Gómez-Fernández J C
A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.
The Biochemical journal 1999;337 ( Pt 3)():387-95.
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1998: Velasco-Guillén I; Corbalán-García S; Gómez-Fernández J C; Teruel J A
Location of N-cyclohexyl-N'-(4-dimethyl-amino-alpha-naphthyl)carbodiimide- binding site in sarcoplasmic reticulum Ca2+-transporting ATPase.
European journal of biochemistry / FEBS 1998;253(1):339-44.
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1998: Corbalan-Garcia S; Margarit S M; Galron D; Yang S S; Bar-Sagi D
Regulation of Sos activity by intramolecular interactions.
Molecular and cellular biology 1998;18(2):880-6.
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1997: Chen R H; Corbalan-Garcia S; Bar-Sagi D
The role of the PH domain in the signal-dependent membrane targeting of Sos.
The EMBO journal 1997;16(6):1351-9.
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1996: Corbalan-Garcia S; Yang S S; Degenhardt K R; Bar-Sagi D
Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2.
Molecular and cellular biology 1996;16(10):5674-82.
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1996: Corbalán-García S; Teruel J A; Gómez-Fernández J C
Involvement of an arginyl residue in the nucleotide-binding site of Ca(2+)-ATPase from sarcoplasmic reticulum as seen by reaction with phenylglyoxal.
The Biochemical journal 1996;318 ( Pt 1)():179-85.
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1996: Corbalan-Garcia S; Degenhardt K R; Bar-Sagi D
Insulin-induced dissociation of Sos from Grb2 does not contribute to the down regulation of Ras activation.
Oncogene 1996;12(5):1063-8.
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1994: Gómez-Fernández J C; Corbalán-García S; Villalaín J; Teruel J A
Structural aspects of the Ca(2+)-ATPase from sarcoplasmic reticulum.
Biochemical Society transactions 1994;22(3):826-9.
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1994: Corbalan-Garcia S; Teruel J A; Gomez-Fernandez J C
Chemical modification of Ca(2+)-ATPase from sarcoplasmic reticulum with phenylglyoxal.
Biochemical Society transactions 1994;22(3):381S.
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1994: Corbalán-García S; Teruel J A; Villalaín J; Gómez-Fernández J C
Extensive proteolytic digestion of the (Ca2+ + Mg2+)-ATPase from sarcoplasmic reticulum leads to a highly hydrophobic proteinaceous residue with a mainly alpha-helical structure.
Biochemistry 1994;33(27):8247-54.
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1993: Corbalán-García S; Teruel J A; Varón R; García-Cánovas F; Gómez-Fernández J C
A kinetic study of an unstable enzyme measured through coupling reactions. Application to the self-inactivation of detergent-solubilized Ca(2+)-ATPase from sarcoplasmic reticulum.
Biochimica et biophysica acta 1993;1203(1):45-52.
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1993: Corbalan-Garcia S; Teruel J A; Gomez-Fernandez J C
Intramolecular distances within the Ca(2+)-ATPase from sarcoplasmic reticulum as estimated through fluorescence energy transfer between probes.
European journal of biochemistry / FEBS 1993;217(2):737-44.
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1992: Corbalan-Garcia S; Teruel J A; Gomez-Fernandez J C
Characterization of ruthenium red-binding sites of the Ca(2+)-ATPase from sarcoplasmic reticulum and their interaction with Ca(2+)-binding sites.
The Biochemical journal 1992;287 ( Pt 3)():767-74.
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1992: Corbalan-Garcia S; Teruel J A; Gomez-Fernandez J C
Interaction of ruthenium red with the calcium binding sites of sarcoplasmic reticulum Ca(2+)-ATPase.
Biochemical Society transactions 1992;20(2):185S.
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