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Hon Kit Wong

Research Profile

Living Beings

Anatomy

Chemicals & Drugs

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Huntington's Disease

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Autophagy

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Publications

TOP 3
Hon Kit Wong; Johanna Lahdenranta; Walid S Kamoun; Annie W Chan; Andrea I McClatchey; Scott R Plotkin; Rakesh K Jain; Emmanuelle di Tomaso
Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.
Peter O Bauer; Anand Goswami; Hon Kit Wong; Misako Okuno; Masaru Kurosawa; Mizuki Yamada; Haruko Miyazaki; Gen Matsumoto; Yoshihiro Kino; Yoshitaka Nagai; Nobuyuki Nukina
Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein.
Peter O Bauer; Hon Kit Wong; Fumitaka Oyama; Anand Goswami; Misako Okuno; Yoshihiro Kino; Haruko Miyazaki; Nobuyuki Nukina
Inhibition of Rho kinases enhances the degradation of mutant huntingtin.

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All Publications

2010: Hon Kit Wong; Johanna Lahdenranta; Walid S Kamoun; Annie W Chan; Andrea I McClatchey; Scott R Plotkin; Rakesh K Jain; Emmanuelle di Tomaso
Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.
Cancer research 2010;70(9):3483-93.
2010: Peter O Bauer; Anand Goswami; Hon Kit Wong; Misako Okuno; Masaru Kurosawa; Mizuki Yamada; Haruko Miyazaki; Gen Matsumoto; Yoshihiro Kino; Yoshitaka Nagai; Nobuyuki Nukina
Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein.
Nature biotechnology 2010;28(3):256-63.
2009: Peter O Bauer; Hon Kit Wong; Fumitaka Oyama; Anand Goswami; Misako Okuno; Yoshihiro Kino; Haruko Miyazaki; Nobuyuki Nukina
Inhibition of Rho kinases enhances the degradation of mutant huntingtin.
The Journal of biological chemistry 2009;284(19):13153-64.
2008: Hon Kit Wong; Peter O Bauer; Masaru Kurosawa; Anand Goswami; Chika Washizu; Yoko Machida; Asako Tosaki; Mizuki Yamada; Thomas Knöpfel; Takemichi Nakamura; Nobuyuki Nukina
Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism.
Human molecular genetics 2008;17(20):3223-35.
2007: Haruko Miyazaki; Fumitaka Oyama; Hon Kit Wong; Kumi Kaneko; Takashi Sakurai; Akira Tamaoka; Nobuyuki Nukina
BACE1 modulates filopodia-like protrusions induced by sodium channel beta4 subunit.
Biochemical and biophysical research communications 2007;361(1):43-8.
2005: Hon Kit Wong; Michael Fricker; Andreas Wyttenbach; Andreas Villunger; Ewa M Michalak; Andreas Strasser; Aviva M Tolkovsky
Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite.
Molecular and cellular biology 2005;25(19):8732-47.
2005: Hon Kit Wong; Takashi Sakurai; Fumitaka Oyama; Kumi Kaneko; Koji Wada; Haruko Miyazaki; Masaru Kurosawa; Bart De Strooper; Paul Saftig; Nobuyuki Nukina
beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase.
The Journal of biological chemistry 2005;280(24):23009-17.
2005: Svetlana Kotliarova; Nihar Ranjan Jana; Naoaki Sakamoto; Masaru Kurosawa; Haruko Miyazaki; Munenori Nekooki; Hiroshi Doi; Yoko Machida; Hon Kit Wong; Taishi Suzuki; Chiharu Uchikawa; Yuri Kotliarov; Kazuyo Uchida; Yoshiro Nagao; Utako Nagaoka; Akira Tamaoka; Kiyomitsu Oyanagi; Fumitaka Oyama; Nobuyuki Nukina
Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates.
Journal of neurochemistry 2005;93(3):641-53.
2003: Nikolaus J Sucher; Konrad Kohler; Lalitha Tenneti; Hon Kit Wong; Tatiana Gründer; Sascha Fauser; Thomas Wheeler-Schilling; Nobuki Nakanishi; Stuart A Lipton; Elke Guenther
N-methyl-D-aspartate receptor subunit NR3A in the retina: developmental expression, cellular localization, and functional aspects.
Investigative ophthalmology & visual science 2003;44(10):4451-6.
2002: Hon Kit Wong; Xiao-Bo Liu; Maria F Matos; Shing-Fai Chan; Isabel Pérez-Otaño; Megan Boysen; Jiankun Cui; Nobuki Nakanishi; James Trimmer; Edward G Jones; Stuart A Lipton; Nikolaus J Sucher
Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain.
The Journal of comparative neurology 2002;450(4):303-17.
2002: Yasnory F Sasaki; Thomas Rothe; Louis S Premkumar; Saumya Das; Jiankun Cui; Maria V Talantova; Hon Kit Wong; Xiandi Gong; Shing-Fai Chan; Dongxian Zhang; Nobuki Nakanishi; Nikolaus J Sucher; Stuart A Lipton
Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons.
Journal of neurophysiology 2002;87(4):2052-63.
2001: Albert Cheung Hoi Yu; Hon Kit Wong; H W Yung; Lok Ting Lau
Ischemia-induced apoptosis in primary cultures of astrocytes.
Glia 2001;35(2):121-30.