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Andrzej Dlugosz

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Paul W Harms; Craig N Johnson; Timothy M Johnson; Kevin T Nash; Rajiv M Patel; Dafydd G Thomas; Monique Verhaegen; Stephanie Daignault; Andrzej Dlugosz; James T Elder; Douglas R Fullen; Thomas J Giordano; Johann Gudjonsson; Christopher K Bichakjian
Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis.
Li-Jyun Syu; Manas Tetarbe; Dawn Wilbert; Xinlei Zheng; Kathryn A Eaton; Mohamad El-Zaatari; Jennifer Ferris; Marina Grachtchouk; Deborah L Gumucio; Ashley Kaatz; Theresa M Keeley; Zhiping Liu; Juanita L Merchant; Joanna Pero; Xiotan Qiao; Linda C Samuelson; Andrzej Dlugosz
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
Andrzej Dlugosz; Sid Agrawal; Peter Kirkpatrick
Vismodegib.

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2013: Paul W Harms; Craig N Johnson; Timothy M Johnson; Kevin T Nash; Rajiv M Patel; Dafydd G Thomas; Monique Verhaegen; Stephanie Daignault; Andrzej Dlugosz; James T Elder; Douglas R Fullen; Thomas J Giordano; Johann Gudjonsson; Christopher K Bichakjian
Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis.
The Journal of investigative dermatology 2013;133(4):936-45.
2012: Li-Jyun Syu; Manas Tetarbe; Dawn Wilbert; Xinlei Zheng; Kathryn A Eaton; Mohamad El-Zaatari; Jennifer Ferris; Marina Grachtchouk; Deborah L Gumucio; Ashley Kaatz; Theresa M Keeley; Zhiping Liu; Juanita L Merchant; Joanna Pero; Xiotan Qiao; Linda C Samuelson; Andrzej Dlugosz
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
The American journal of pathology 2012;181(6):2114-25.
2012: Andrzej Dlugosz; Sid Agrawal; Peter Kirkpatrick
Vismodegib.
Nature reviews. Drug discovery 2012;11(6):437-8.
2012: Stuart H Yuspa; Andrzej Dlugosz; Kenneth H Kraemer; Molly Kulesz-Martin; Dennis R Roop; Jackie R Bickenbach
Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research.
The Journal of investigative dermatology 2012;132(5):1317-20.
2012: Markus Eberl; Alexandre N Ermilov; Hendrik Hache; Cornelia Hauser-Kronberger; Stefan Klingler; Hans Lehrach; Andrea Loipetzberger; Doris Mangelberger; Wilfried Nietfeld; Harald SCHNIDAR; Maria Sibilia; Flavio Solca; Monique Verhaegen; Christoph Wierling; Kerstin Zoidl; Hans-Christian Bauer; Christopher K Bichakjian; Helene Damhofer; Andrzej Dlugosz; Fritz Aberger
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells.
EMBO molecular medicine 2012;4(3):218-33.
2012: Milena Saqui-Salces; Li-Jyun Syu; Natalia A Veniaminova; Meghna Waghray; Evelyn Covés-Datson; Andrzej Dlugosz; Juanita L Merchant
Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.
PloS one 2012;7(10):e48039.
2011: Heather M Ames; Christopher K Bichakjian; Andrzej Dlugosz; Douglas R Fullen; Timothy M Johnson; Grace Y Liu; Katherine I Oravecz-Wilson; Monique Verhaegen; Theodora S Ross
Huntingtin-interacting protein 1: a Merkel cell carcinoma marker that interacts with c-Kit.
The Journal of investigative dermatology 2011;131(10):2113-20.
2011: Marina Grachtchouk; Joanna Pero; Steven H Yang; Alexandre N Ermilov; L Evan Michael; Aiqin Wang; Dawn Wilbert; Rajiv M Patel; Jennifer Ferris; James Diener; Mary Allen; Seokchun Lim; Li-Jyun Syu; Monique Verhaegen; Andrzej Dlugosz
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
The Journal of clinical investigation 2011;121(5):1768-81.
2010: Daryle Joseph Depianto; Michelle L Kerns; Andrzej Dlugosz; Pierre A Coulombe
Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin.
Nature genetics 2010;42(10):910-4.
2010: Divya Khanna; Christin A Hamilton; Mahaveer S Bhojani; Kuei C Lee; Andrzej Dlugosz; Brian D Ross; Alnawaz Rehemtulla
A transgenic mouse for imaging caspase-dependent apoptosis within the skin.
The Journal of investigative dermatology 2010;130(7):1797-806.
2010: Xiping Cheng; Jie Jin; Lily Hu; Dongbiao Shen; Xian-Ping Dong; Mohammad A Samie; Jayne Knoff; Brian Eisinger; Mei-Ling Liu; Susan M Huang; Michael J Caterina; Peter J Dempsey; Lowell Evan Michael; Andrzej Dlugosz; Nancy C Andrews; David E Clapham; Haoxing Xu
TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation.
Cell 2010;141(2):331-43.
2009: Andrzej Dlugosz; Moshe Talpaz
Following the hedgehog to new cancer therapies.
The New England journal of medicine 2009;361(12):1202-5.
2009: Sunny Wong; Allen D Seol; Po-Lin So; Alexandre N Ermilov; Christopher K Bichakjian; Ervin H Epstein; Andrzej Dlugosz; Jeremy F Reiter
Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis.
Nature medicine 2009;15(9):1055-61.
2009: Young-Goo Han; Hong Joo Kim; Andrzej Dlugosz; David W Ellison; Richard J Gilbertson; Arturo Alvarez-Buylla
Dual and opposing roles of primary cilia in medulloblastoma development.
Nature medicine 2009;15(9):1062-5.
2009: Andrey A Sharov; Andrei N Mardaryev; Tatyana Y Sharova; Marina Grachtchouk; Ruzanna Atoyan; H Randolph Byers; John T Seykora; Paul Overbeek; Andrzej Dlugosz; Vladimir A Botchkarev
Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways.
The American journal of pathology 2009;175(3):1303-14.
2009: Asa Kolterud; Ann S Grosse; William J Zacharias; Katherine D Walton; Katherine E Kretovich; Blair B Madison; Meghna Waghray; Jennifer E Ferris; Chunbo Hu; Juanita L Merchant; Andrzej Dlugosz; Andreas Kottmann; Deborah L Gumucio
Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning.
Gastroenterology 2009;137(2):618-28.
2009: Zhipeng Fan; Juan Du; Huimin Liu; Honglai Zhang; Andrzej Dlugosz; Cun-Yu Wang; Ming Fan; Yan Shen; Songlin Wang
A susceptibility locus on 1p32-1p34 for congenital macrostomia in a Chinese family and identification of a novel PTCH2 mutation.
American journal of medical genetics. Part A 2009;149A(3):521-4.
2009: Johann Gudjonsson; Abhishek Aphale; Marina Grachtchouk; Jun Ding; Rajan P Nair; Timothy S Wang; John J Voorhees; Andrzej Dlugosz; James T Elder
Lack of evidence for activation of the hedgehog pathway in psoriasis.
The Journal of investigative dermatology 2009;129(3):635-40.
2008: Lowell Evan Michael; Bart A Westerman; Alexandre N Ermilov; Aiqin Wang; Jennifer Ferris; Jianhong Liu; Marleen Blom; David W Ellison; Maarten van Lohuizen; Andrzej Dlugosz
Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion.
Neoplasia (New York, N.Y.) 2008;10(12):1343-9, 5p following 1349.
2008: Steven Hoseong Yang; Thomas Andl; Vladimir Grachtchouk; Aiqin Wang; Jianhong Liu; Li-Jyun Syu; Jenny Ferris; Timothy S Wang; Adam B Glick; Sarah E Millar; Andrzej Dlugosz
Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling.
Nature genetics 2008;40(9):1130-5.
2008: Yuhang Zhang; Thomas Andl; Steven H Yang; Monica Teta; Fei Liu; John T Seykora; John W Tobias; Stefano Piccolo; Ruth Schmidt-Ullrich; Andras Nagy; Makoto M Taketo; Andrzej Dlugosz; Sarah E Millar
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.
Development (Cambridge, England) 2008;135(12):2161-72.
2008: Fei Liu; Emily Y Chu; Brenda Watt; Yuhang Zhang; Natalie M Gallant; Thomas Andl; Steven H Yang; Min Min Lu; Stefano Piccolo; Ruth Schmidt-Ullrich; Makoto M Taketo; Edward Morrisey; Radhika Atit; Andrzej Dlugosz; Sarah E Millar
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis.
Developmental biology 2008;313(1):210-24.
2007: Yana Zavros; Meghna Waghray; Arthur Tessier; Longchuan Bai; Andrea Todisco; Deborah L Gumucio; Linda C Samuelson; Andrzej Dlugosz; Juanita L Merchant
Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation.
The Journal of biological chemistry 2007;282(46):33265-74.
2007: Monica Dentice; Cristina Luongo; Stephen Huang; Raffaele Ambrosio; Andrea Elefante; Delphine Mirebeau-Prunier; Ann Marie Zavacki; Gianfranco Fenzi; Marina Grachtchouk; Mark E Hutchin; Andrzej Dlugosz; Antonio Bianco; Caterina Missero; P Reed Larsen; Domenico Salvatore
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14466-71.
2007: Sarah V Bradley; Teresa S Hyun; Katherine I Oravecz-Wilson; Lina Li; Erik I Waldorff; Alexander N Ermilov; Steven A Goldstein; Claire X Zhang; David G Drubin; Kate Varela; Albert F Parlow; Andrzej Dlugosz; Theodora S Ross
Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1.
Human molecular genetics 2007;16(11):1279-92.
2007: Vidyullatha Vasireddy; Yoshikazu Uchida; Norman Salem; Soo Yeon Kim; Md Nawajes A Mandal; G Bhanuprakash Reddy; Ravi Bodepudi; Nathan L Alderson; Johnie C Brown; Hiroko Hama; Andrzej Dlugosz; Peter M Elias; Walter M Holleran; Radha Ayyagari
Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death.
Human molecular genetics 2007;16(5):471-82.
2007: Jack T Mosher; Kelly J Yeager; Genevieve M Kruger; Nancy M Joseph; Mark E Hutchin; Andrzej Dlugosz; Sean J Morrison
Intrinsic differences among spatially distinct neural crest stem cells in terms of migratory properties, fate determination, and ability to colonize the enteric nervous system.
Developmental biology 2007;303(1):1-15.
2007: Marina Pasca di Magliano; Andrew V Biankin; Patrick W Heiser; David A Cano; Pedro J A Gutierrez; Therese B Deramaudt; Davendra Segara; Amanda C Dawson; James G Kench; Susan M Henshall; Robert L Sutherland; Andrzej Dlugosz; Anil K Rustgi; Matthias Hebrok
Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.
PloS one 2007;2(11):e1155.
2007: Fei Liu; Shoba Thirumangalathu; Natalie M Gallant; Steven H Yang; Cristi L Stoick-Cooper; Seshamma T Reddy; Thomas Andl; Makoto M Taketo; Andrzej Dlugosz; Randall T Moon; Linda A Barlow; Sarah E Millar
Wnt-beta-catenin signaling initiates taste papilla development.
Nature genetics 2007;39(1):106-12.
2006: Marina Pasca di Magliano; Shigeki Sekine; Alexandre Ermilov; Jenny Ferris; Andrzej Dlugosz; Matthias Hebrok
Hedgehog/Ras interactions regulate early stages of pancreatic cancer.
Genes & development 2006;20(22):3161-73.
2006: Marina Grachtchouk; Jianhong Liu; Aiqin Wang; Lebing Wei; Christopher K Bichakjian; Jonathan Garlick; Augusto F G Paulino; Thomas J Giordano; Andrzej Dlugosz
Odontogenic keratocysts arise from quiescent epithelial rests and are associated with deregulated hedgehog signaling in mice and humans.
The American journal of pathology 2006;169(3):806-14.
2006: Neehar Bhatia; Saravanan Thiyagarajan; Irina Elcheva; Mohammed Saleem; Andrzej Dlugosz; Hasan Mukhtar; Vladimir S Spiegelman
Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.
The Journal of biological chemistry 2006;281(28):19320-6.
2005: Erich Roessler; Alexandre N Ermilov; Dorothy Katherine Grange; Aiqin Wang; Marina Grachtchouk; Andrzej Dlugosz; Maximilian Muenke
A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2.
Human molecular genetics 2005;14(15):2181-8.
2005: Mark E Hutchin; Muhammed S T Kariapper; Marina Grachtchouk; Aiqin Wang; Lebing Wei; Donelle Cummings; Jianhong Liu; L Evan Michael; Adam Glick; Andrzej Dlugosz
Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle.
Genes & development 2005;19(2):214-23.
2004: Anna Brancaccio; Annunziata Minichiello; Marina Grachtchouk; Dario Antonini; Hong Sheng; Rosanna Parlato; Nina Dathan; Andrzej Dlugosz; Caterina Missero
Requirement of the forkhead gene Foxe1, a target of sonic hedgehog signaling, in hair follicle morphogenesis.
Human molecular genetics 2004;13(21):2595-606.
2004: Chunhua Cui; Thomas Elsam; Qinjie Tian; John T Seykora; Marina Grachtchouk; Andrzej Dlugosz; Hung Tseng
Gli proteins up-regulate the expression of basonuclin in Basal cell carcinoma.
Cancer research 2004;64(16):5651-8.
2003: Mary Allen; Marina Grachtchouk; Hong Sheng; Vladimir Grachtchouk; Anna Wang; Lebing Wei; Jianhong Liu; Angel Ramirez; Daniel Metzger; Pierre Chambon; Jose Jorcano; Andrzej Dlugosz
Hedgehog signaling regulates sebaceous gland development.
The American journal of pathology 2003;163(6):2173-8.
2003: Vladimir Grachtchouk; Marina Grachtchouk; Lori Lowe; Tim Johnson; Lebing Wei; Aiqin Wang; Frederic J de Sauvage; Andrzej Dlugosz
The magnitude of hedgehog signaling activity defines skin tumor phenotype.
The EMBO journal 2003;22(11):2741-51.
2003: David Van Mater; Frank T Kolligs; Andrzej Dlugosz; Eric R Fearon
Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice.
Genes & development 2003;17(10):1219-24.
2003: Pleasantine Mill; Rong Mo; Hong Fu; Marina Grachtchouk; Peter C W Kim; Andrzej Dlugosz; Chi-Chung Hui
Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.
Genes & development 2003;17(2):282-94.
2002: Andrzej Dlugosz; Glenn Merlino; Stuart H Yuspa
Progress in cutaneous cancer research.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2002;7(1):17-26.
2002: Hong Sheng; Sara Goich; Aiqin Wang; Marina Grachtchouk; Lori Lowe; Rong Mo; Kui Lin; Frederic J de Sauvage; Hiroshi Sasaki; Chi-Chung Hui; Andrzej Dlugosz
Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype.
Cancer research 2002;62(18):5308-16.
2000: Dana L Sachs; L Su; Andrzej Dlugosz
Verrucous annular ulcerated hip plaques. Diagnosis: superficial granulomatous pyoderma form of pyoderma gangrenosum.
Archives of dermatology 2000;136(10):1263-8.
2000: Mitchell F Denning; Andrzej Dlugosz; Christina Cheng; Peter J Dempsey; R J Coffey; David Threadgill; Terry Magnuson; Stuart H Yuspa
Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes.
Experimental dermatology 2000;9(3):192-9.
2000: alison mcbride; Andrzej Dlugosz; Carl Baker
Production of infectious bovine papillomavirus from cloned viral DNA by using an organotypic raft/xenograft technique.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5534-9.
2000: Marina Grachtchouk; Rong Mo; S Yu; X Zhang; H Sasaki; Chi-Chung Hui; Andrzej Dlugosz
Basal cell carcinomas in mice overexpressing Gli2 in skin.
Nature genetics 2000;24(3):216-7.
1999: Q Ding; S i Fukami; X Meng; Yukiko Nishizaki; X Zhang; H Sasaki; Andrzej Dlugosz; M Nakafuku; C c Hui
Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.
Current biology : CB 1999;9(19):1119-22.
1999: Andrzej Dlugosz
The Hedgehog and the hair follicle: a growing relationship.
The Journal of clinical investigation 1999;104(7):851-3.
1999: Chin Chiang; R Z Swan; Marina Grachtchouk; M Bolinger; Ying Litingtung; E K Robertson; Michael K Cooper; W Gaffield; Heiner Westphal; Philip A Beachy; Andrzej Dlugosz
Essential role for Sonic hedgehog during hair follicle morphogenesis.
Developmental biology 1999;205(1):1-9.
1998: Y S Lee; Stuart H Yuspa; Andrzej Dlugosz
Differentiation of cultured human epidermal keratinocytes at high cell densities is mediated by endogenous activation of the protein kinase C signaling pathway.
The Journal of investigative dermatology 1998;111(5):762-6.
1997: Andrzej Dlugosz; L Hansen; Christina Cheng; N Alexander; Mitchell F Denning; David Threadgill; Terry Magnuson; R J Coffey; Stuart H Yuspa
Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras.
Cancer research 1997;57(15):3180-8.
1997: Laura A Hansen; N Alexander; M E Hogan; J P Sundberg; Andrzej Dlugosz; David Threadgill; Terry Magnuson; Stuart H Yuspa
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development.
The American journal of pathology 1997;150(6):1959-75.
1997: Y S Lee; Andrzej Dlugosz; R McKay; Nicholas Dean; Stuart H Yuspa
Definition by specific antisense oligonucleotides of a role for protein kinase C alpha in expression of differentiation markers in normal and neoplastic mouse epidermal keratinocytes.
Molecular carcinogenesis 1997;18(1):44-53.
1996: Andrzej Dlugosz
Signal transduction in normal and neoplastic keratinocytes.
The Journal of dermatology 1996;23(11):751-5.
1996: M H Wang; Andrzej Dlugosz; Y Sun; T Suda; A Skeel; Edward J Leonard
Macrophage-stimulating protein induces proliferation and migration of murine keratinocytes.
Experimental cell research 1996;226(1):39-46.
1996: Susan Rutberg; E Saez; A Glick; Andrzej Dlugosz; Bruce M Spiegelman; Stuart H Yuspa
Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins.
Oncogene 1996;13(1):167-76.
1996: C Stanwell; Andrzej Dlugosz; Stuart H Yuspa
Staurosporine induces a complete program of terminal differentiation in neoplastic mouse keratinocytes via activation of protein kinase C.
Carcinogenesis 1996;17(6):1259-65.
1996: Stuart H Yuspa; Andrzej Dlugosz; Mitchell F Denning; A B Glick
Multistage carcinogenesis in the skin.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1996;1(2):147-50.
1996: Mitchell F Denning; Andrzej Dlugosz; David Threadgill; Terry Magnuson; Stuart H Yuspa
Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta.
The Journal of biological chemistry 1996;271(10):5325-31.
1996: C Stanwell; Mitchell F Denning; Susan Rutberg; C Cheng; Stuart H Yuspa; Andrzej Dlugosz
Staurosporine induces a sequential program of mouse keratinocyte terminal differentiation through activation of PKC isozymes.
The Journal of investigative dermatology 1996;106(3):482-9.
1995: David Threadgill; Andrzej Dlugosz; L A Hansen; Tamar Tennenbaum; U Lichti; D Yee; Christian LaMantia; T Mourton; Karl Herrup; R C Harris
Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype.
Science (New York, N.Y.) 1995;269(5221):230-4.
1995: Andrzej Dlugosz; C Cheng; E K Williams; N Darwiche; Peter J Dempsey; B Mann; A R Dunn; R J Coffey; Stuart H Yuspa
Autocrine transforming growth factor alpha is dispensible for v-rasHa-induced epidermal neoplasia: potential involvement of alternate epidermal growth factor receptor ligands.
Cancer research 1995;55(9):1883-93.
1995: Z Szallasi; K Kosa; C B Smith; Andrzej Dlugosz; E K Williams; Stuart H Yuspa; Peter M Blumberg
Differential regulation by anti-tumor-promoting 12-deoxyphorbol-13-phenylacetate reveals distinct roles of the classical and novel protein kinase C isozymes in biological responses of primary mouse keratinocytes.
Molecular pharmacology 1995;47(2):258-65.
1995: Mitchell F Denning; Andrzej Dlugosz; E K Williams; Z Szallasi; Peter M Blumberg; Stuart H Yuspa
Specific protein kinase C isozymes mediate the induction of keratinocyte differentiation markers by calcium.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(2):149-57.
1995: Stuart H Yuspa; Henry Hennings; Andrzej Dlugosz; Tamar Tennenbaum; A Glick
The role of growth factors in mouse skin tumor promotion and premalignant progression.
Progress in clinical and biological research 1995;391():39-48.
1995: Andrzej Dlugosz; A B Glick; Tamar Tennenbaum; Wendy C Weinberg; Stuart H Yuspa
Isolation and utilization of epidermal keratinocytes for oncogene research.
Methods in enzymology 1995;254():3-20.
1994: Andrzej Dlugosz; C Cheng; E K Williams; A G Dharia; Mitchell F Denning; Stuart H Yuspa
Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha.
Cancer research 1994;54(24):6413-20.
1994: Andrzej Dlugosz; C Cheng; Mitchell F Denning; Peter J Dempsey; R J Coffey; Stuart H Yuspa
Keratinocyte growth factor receptor ligands induce transforming growth factor alpha expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(12):1283-92.
1994: Z Szallasi; Mitchell F Denning; C B Smith; Andrzej Dlugosz; Stuart H Yuspa; George R Pettit; Peter M Blumberg
Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation.
Molecular pharmacology 1994;46(5):840-50.
1994: Stuart H Yuspa; Andrzej Dlugosz; C K Cheng; Mitchell F Denning; Tamar Tennenbaum; A B Glick; Wendy C Weinberg
Role of oncogenes and tumor suppressor genes in multistage carcinogenesis.
The Journal of investigative dermatology 1994;103(5 Suppl):90S-95S.
1994: Andrzej Dlugosz; Stuart H Yuspa
Protein kinase C regulates keratinocyte transglutaminase (TGK) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium.
The Journal of investigative dermatology 1994;102(4):409-14.
1993: Mitchell F Denning; Andrzej Dlugosz; M K Howett; Stuart H Yuspa
Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta.
The Journal of biological chemistry 1993;268(35):26079-81.
1993: C Cheng; Tamar Tennenbaum; Peter J Dempsey; R J Coffey; Stuart H Yuspa; Andrzej Dlugosz
Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(4):317-27.
1993: J E Strickland; Andrzej Dlugosz; Henry Hennings; Stuart H Yuspa
Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation.
Carcinogenesis 1993;14(2):205-9.
1993: Stuart H Yuspa; K Punnonen; E Lee; Henry Hennings; J Strickland; C Cheng; A Glick; Andrzej Dlugosz
The in vitro analysis of biochemical changes relevant to skin carcinogenesis.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;128():299-308.
1993: Andrzej Dlugosz; Stuart H Yuspa
Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C.
The Journal of cell biology 1993;120(1):217-25.
1992: E Lee; K Punnonen; C Cheng; A Glick; Andrzej Dlugosz; Stuart H Yuspa
Analysis of phospholipid metabolism in murine keratinocytes transformed by the v-ras oncogene: relationship of phosphatidylinositol turnover and cytokine stimulation to the transformed phenotype.
Carcinogenesis 1992;13(12):2367-73.
1992: Stuart H Yuspa; K Punnonen; E Lee; Henry Hennings; J E Strickland; C Cheng; A Glick; Andrzej Dlugosz
Alterations in the biology and biochemistry of keratinocytes induced by the ras oncogene.
Progress in clinical and biological research 1992;376():103-15.
1992: Andrzej Dlugosz; Mischak Harald; J Frederic Mushinski; Stuart H Yuspa
Transcripts encoding protein kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells.
Molecular carcinogenesis 1992;5(4):286-92.
1991: Andrzej Dlugosz; Stuart H Yuspa
Staurosporine induces protein kinase C agonist effects and maturation of normal and neoplastic mouse keratinocytes in vitro.
Cancer research 1991;51(17):4677-84.
1989: Thomas G O'Brien; L Dzubow; Andrzej Dlugosz; Susan K Gilmour; K O'Donnell; O Hietala
Regulation of ornithine decarboxylase in normal and neoplastic mouse and human epidermis.
Progress in clinical and biological research 1989;298():213-31.
1988: O Hietala; L Dzubow; Andrzej Dlugosz; J A Pyle; F Jenney; Susan K Gilmour; Thomas G O'Brien
Activation of human squamous cell carcinoma ornithine decarboxylase activity by guanosine triphosphate.
Cancer research 1988;48(5):1252-7.
1987: M R Khouri; S H Saul; Andrzej Dlugosz; R D Soloway
Hepatocanalicular injury associated with vitamin A derivative etretinate. An idiosyncratic hypersensitivity reaction.
Digestive diseases and sciences 1987;32(10):1207-11.
1985: H Holtzer; S Forry-Schaudies; Andrzej Dlugosz; P Antin; G Dubyak
Interactions between IFs, microtubules, and myofibrils in fibrogenic and myogenic cells.
Annals of the New York Academy of Sciences 1985;455():106-25.
1984: Andrzej Dlugosz; P B Antin; V T Nachmias; H Holtzer
The relationship between stress fiber-like structures and nascent myofibrils in cultured cardiac myocytes.
The Journal of cell biology 1984;99(6):2268-78.
1983: Andrzej Dlugosz; S J Tapscott; H Holtzer
Effects of phorbol 12-myristate 13-acetate on the differentiation program of embryonic chick skeletal myoblasts.
Cancer research 1983;43(6):2780-9.
1983: Franco Tatò; Stefano Alemà; Andrzej Dlugosz; David Boettiger; H Holtzer; G Cossu; M Pacifici
Development of 'revertant' myotubes in cultures of Rous sarcoma virus transformed avian myogenic cells.
Differentiation; research in biological diversity 1983;24(2):131-9.
1982: J Croop; G Dubyak; Y Toyama; Andrzej Dlugosz; A Scarpa; H Holtzer
Effects of 12-O-tetradecanoyl-phorbol-13-acetate on Myofibril integrity and Ca2+ content in developing myotubes.
Developmental biology 1982;89(2):460-74.
1982: H Holtzer; M Pacifici; R Payette; J Croop; Andrzej Dlugosz; Y Toyama
TPA reversibly blocks the differentiation of chick myogenic, chondrogenic, and melanogenic cells.
Carcinogenesis; a comprehensive survey 1982;7():347-57.
1980: J Croop; Y Toyama; Andrzej Dlugosz; H Holtzer
Selective effects of phorbol 12-myristate 13-acetate on myofibrils and 10-nm filaments.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(9):5273-7.