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Lubbert Dijkhuizen
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29
Dijkstra, Bauke
24
van der Maarel, M J E C
18
Leemhuis, Hans
13
Uitdehaag, Joost
13
Kralj, Slavko
12
Meijer, Wim
12
Rozeboom, Henriëtte
11
van der Veen, Bart
9
van der Geize, Robert
9
Euverink, Gert-Jan
9
Wösten, Han
8
Claessen, Dennis
8
Kalk, Kor
8
Hessels, Gerda
7
van Keulen, Geertje
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All Publications
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2009: Malik Amarila; Radji Maksum; Kralj Slavko; Dijkhuizen Lubbert
Screening of lactic acid bacteria from Indonesia reveals glucansucrase and fructansucrase genes in two different Weissella confusa strains from soya.
FEMS microbiology letters 2009;300(1):131-8.
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2009: de Jong Wouter; Wösten Han A B; Dijkhuizen Lubbert; Claessen Dennis
Attachment of Streptomyces coelicolor is mediated by amyloidal fimbriae that are anchored to the cell surface via cellulose.
Molecular microbiology 2009;73(6):1128-40.
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2009: Petrusma M; Dijkhuizen L; van der Geize R
Rhodococcus rhodochrous DSM 43269 3-ketosteroid 9alpha-hydroxylase, a two-component iron-sulfur-containing monooxygenase with subtle steroid substrate specificity.
Applied and environmental microbiology 2009;75(16):5300-7.
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2009: Kelly Ronan M; Dijkhuizen Lubbert; Leemhuis Hans
The evolution of cyclodextrin glucanotransferase product specificity.
Applied microbiology and biotechnology 2009;84(1):119-33.
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2009: Kelly Ronan M; Dijkhuizen Lubbert; Leemhuis Hans
Starch and alpha-glucan acting enzymes, modulating their properties by directed evolution.
Journal of biotechnology 2009;140(3-4):184-93.
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2009: de Jong Wouter; Manteca Angel; Sanchez Jesus; Bucca Giselda; Smith Colin P; Dijkhuizen Lubbert; Claessen Dennis; Wösten Han A B
NepA is a structural cell wall protein involved in maintenance of spore dormancy in Streptomyces coelicolor.
Molecular microbiology 2009;71(6):1591-603.
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2009: Leemhuis Hans; Kelly Ronan M; Dijkhuizen Lubbert
Directed evolution of enzymes: Library screening strategies.
IUBMB life 2009;61(3):222-8.
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2009: Palomo M; Kralj S; van der Maarel M J E C; Dijkhuizen L
The unique branching patterns of Deinococcus glycogen branching enzymes are determined by their N-terminal domains.
Applied and environmental microbiology 2009;75(5):1355-62.
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2008: Kralj Slavko; van Leeuwen Sander S; Valk Vincent; Eeuwema Wieger; Kamerling Johannis P; Dijkhuizen Lubbert
Hybrid reuteransucrase enzymes reveal regions important for glucosidic linkage specificity and the transglucosylation/hydrolysis ratio.
The FEBS journal 2008;275(23):6002-10.
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2008: van der Geize R; de Jong W; Hessels G I; Grommen A W F; Jacobs A A C; Dijkhuizen L
A novel method to generate unmarked gene deletions in the intracellular pathogen Rhodococcus equi using 5-fluorocytosine conditional lethality.
Nucleic acids research 2008;36(22):e151.
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2008: Mohn William W; van der Geize Robert; Stewart Gordon R; Okamoto Sachi; Liu Jie; Dijkhuizen Lubbert; Eltis Lindsay D
The actinobacterial mce4 locus encodes a steroid transporter.
The Journal of biological chemistry 2008;283(51):35368-74.
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2008: van der Geize R; Hessels G I; Nienhuis-Kuiper M; Dijkhuizen L
Characterization of a second Rhodococcus erythropolis SQ1 3-ketosteroid 9alpha-hydroxylase activity comprising a terminal oxygenase homologue, KshA2, active with oxygenase-reductase component KshB.
Applied and environmental microbiology 2008;74(23):7197-203.
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2008: Borodina Irina; Siebring Jeroen; Zhang Jie; Smith Colin P; van Keulen Geertje; Dijkhuizen Lubbert; Nielsen Jens
Antibiotic overproduction in Streptomyces coelicolor A3 2 mediated by phosphofructokinase deletion.
The Journal of biological chemistry 2008;283(37):25186-99.
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2008: Wieringa N F; van der Windt H J; Zuiker R R M; Dijkhuizen L; Verkerk M A; Vonk R J; Swart J A A
Positioning functional foods in an ecological approach to the prevention of overweight and obesity.
Obesity reviews : an official journal of the International Association for the Study of Obesity 2008;9(5):464-73.
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2008: van Leeuwen Sander S; Kralj Slavko; Gerwig Gerrit J; Dijkhuizen Lubbert; Kamerling Johannis P
Structural analysis of bioengineered alpha-D-glucan produced by a triple mutant of the Glucansucrase GTF180 enzyme from Lactobacillus reuteri strain 180: generation of (alpha1-->4) linkages in a native (1-->3)(1-->6)-alpha-D-glucan.
Biomacromolecules 2008;9(8):2251-8.
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2008: Kelly Ronan M; Leemhuis Hans; Rozeboom Henriëtte J; van Oosterwijk Niels; Dijkstra Bauke W; Dijkhuizen Lubbert
Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution.
The Biochemical journal 2008;413(3):517-25.
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2008: te Poele Evelien M; Bolhuis Henk; Dijkhuizen Lubbert
Actinomycete integrative and conjugative elements.
Antonie van Leeuwenhoek 2008;94(1):127-43.
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2008: Anwar Munir A; Kralj Slavko; van der Maarel Marc J E C; Dijkhuizen Lubbert
The probiotic Lactobacillus johnsonii NCC 533 produces high-molecular-mass inulin from sucrose by using an inulosucrase enzyme.
Applied and environmental microbiology 2008;74(11):3426-33.
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2008: Yuan Xiao-Lian; van der Kaaij Rachel M; van den Hondel Cees A M J J; Punt Peter J; van der Maarel Marc J E C; Dijkhuizen Lubbert; Ram Arthur F J
Aspergillus niger genome-wide analysis reveals a large number of novel alpha-glucan acting enzymes with unexpected expression profiles.
Molecular genetics and genomics : MGG 2008;279(6):545-61.
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2008: van Leeuwen Sander S; Kralj Slavko; van Geel-Schutten Ineke H; Gerwig Gerrit J; Dijkhuizen Lubbert; Kamerling Johannis P
Structural analysis of the alpha-D-glucan (EPS35-5) produced by the Lactobacillus reuteri strain 35-5 glucansucrase GTFA enzyme.
Carbohydrate research 2008;343(7):1251-65.
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2008: van Leeuwen Sander S; Kralj Slavko; van Geel-Schutten Ineke H; Gerwig Gerrit J; Dijkhuizen Lubbert; Kamerling Johannis P
Structural analysis of the alpha-D-glucan (EPS180) produced by the Lactobacillus reuteri strain 180 glucansucrase GTF180 enzyme.
Carbohydrate research 2008;343(7):1237-50.
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2008: te Poele Evelien M; Samborskyy Markiyan; Oliynyk Markiyan; Leadlay Peter F; Bolhuis Henk; Dijkhuizen Lubbert
Actinomycete integrative and conjugative pMEA-like elements of Amycolatopsis and Saccharopolyspora decoded.
Plasmid 2008;59(3):202-16.
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2008: Kelly Ronan M; Leemhuis Hans; Gätjen Linda; Dijkhuizen Lubbert
Evolution toward small molecule inhibitor resistance affects native enzyme function and stability, generating acarbose-insensitive cyclodextrin glucanotransferase variants.
The Journal of biological chemistry 2008;283(16):10727-34.
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2008: Knol Jan; Bodewits Karin; Hessels Gerda I; Dijkhuizen Lubbert; van der Geize Robert
3-Keto-5alpha-steroid Delta(1)-dehydrogenase from Rhodococcus erythropolis SQ1 and its orthologue in Mycobacterium tuberculosis H37Rv are highly specific enzymes that function in cholesterol catabolism.
The Biochemical journal 2008;410(2):339-46.
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2007: van der Kaaij R M; Janecek S; van der Maarel M J E C; Dijkhuizen L
Phylogenetic and biochemical characterization of a novel cluster of intracellular fungal alpha-amylase enzymes.
Microbiology (Reading, England) 2007;153(Pt 12):4003-15.
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2007: Rohman Ali; van Oosterwijk Niels; Kralj Slavko; Dijkhuizen Lubbert; Dijkstra Bauke W; Puspaningsih Ni Nyoman Tri
Purification, crystallization and preliminary X-ray analysis of a thermostable glycoside hydrolase family 43 beta-xylosidase from Geobacillus thermoleovorans IT-08.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 11):932-5.
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2007: Kelly Ronan M; Leemhuis Hans; Dijkhuizen Lubbert
Conversion of a cyclodextrin glucanotransferase into an alpha-amylase: assessment of directed evolution strategies.
Biochemistry 2007;46(39):11216-22.
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2007: te Poele Evelien M; Habets Marrit N; Tan Geok Yuan Annie; Ward Alan C; Goodfellow Michael; Bolhuis Henk; Dijkhuizen Lubbert
Prevalence and distribution of nucleotide sequences typical for pMEA-like accessory genetic elements in the genus Amycolatopsis.
FEMS microbiology ecology 2007;61(2):285-94.
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2007: van der Kaaij R M; Yuan X-L; Franken A; Ram A F J; Punt P J; van der Maarel M J E C; Dijkhuizen L
Two novel, putatively cell wall-associated and glycosylphosphatidylinositol-anchored alpha-glucanotransferase enzymes of Aspergillus niger.
Eukaryotic cell 2007;6(7):1178-88.
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2007: Barends Thomas R M; Bultema Jelle B; Kaper Thijs; van der Maarel Marc J E C; Dijkhuizen Lubbert; Dijkstra Bauke W
Three-way stabilization of the covalent intermediate in amylomaltase, an alpha-amylase-like transglycosylase.
The Journal of biological chemistry 2007;282(23):17242-9.
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2007: Kaper Thijs; Leemhuis Hans; Uitdehaag Joost C M; van der Veen Bart A; Dijkstra Bauke W; van der Maarel Marc J E C; Dijkhuizen Lubbert
Identification of acceptor substrate binding subsites +2 and +3 in the amylomaltase from Thermus thermophilus HB8.
Biochemistry 2007;46(17):5261-9.
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2007: Goosen Coenie; Yuan Xiao-Lian; van Munster Jolanda M; Ram Arthur F J; van der Maarel Marc J E C; Dijkhuizen Lubbert
Molecular and biochemical characterization of a novel intracellular invertase from Aspergillus niger with transfructosylating activity.
Eukaryotic cell 2007;6(4):674-81.
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2007: Biedendieck Rebekka; Beine Rafael; Gamer Martin; Jordan Eva; Buchholz Klaus; Seibel Jürgen; Dijkhuizen Lubbert; Malten Marco; Jahn Dieter
Export, purification, and activities of affinity tagged Lactobacillus reuteri levansucrase produced by Bacillus megaterium.
Applied microbiology and biotechnology 2007;74(5):1062-73.
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2007: Van der Geize Robert; Yam Katherine; Heuser Thomas; Wilbrink Maarten H; Hara Hirofumi; Anderton Matthew C; Sim Edith; Dijkhuizen Lubbert; Davies Julian E; Mohn William W; Eltis Lindsay D
A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(6):1947-52.
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2007: Pel Herman J; de Winde Johannes H; Archer David B; Dyer Paul S; Hofmann Gerald; Schaap Peter J; Turner Geoffrey; de Vries Ronald P; Albang Richard; Albermann Kaj; Andersen Mikael R; Bendtsen Jannick D; Benen Jacques A E; van den Berg Marco; Breestraat Stefaan; Caddick Mark X; Contreras Roland; Cornell Michael; Coutinho Pedro M; Danchin Etienne G J; Debets Alfons J M; Dekker Peter; van Dijck Piet W M; van Dijk Alard; Dijkhuizen Lubbert; Driessen Arnold J M; d'Enfert Christophe; Geysens Steven; Goosen Coenie; Groot Gert S P; de Groot Piet W J; Guillemette Thomas; Henrissat Bernard; Herweijer Marga; van den Hombergh Johannes P T W; van den Hondel Cees A M J J; van der Heijden Rene T J M; van der Kaaij Rachel M; Klis Frans M; Kools Harrie J; Kubicek Christian P; van Kuyk Patricia A; Lauber Jürgen; Lu Xin; van der Maarel Marc J E C; Meulenberg Rogier; Menke Hildegard; Mortimer Martin A; Nielsen Jens; Oliver Stephen G; Olsthoorn Maurien; Pal Karoly; van Peij Noël N M E; Ram Arthur F J; Rinas Ursula; Roubos Johannes A; Sagt Cees M J; Schmoll Monika; Sun Jibin; Ussery David; Varga Janos; Vervecken Wouter; van de Vondervoort Peter J J; Wedler Holger; Wösten Han A B; Zeng An-Ping; van Ooyen Albert J J; Visser Jaap; Stam Hein
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88.
Nature biotechnology 2007;25(2):221-31.
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2007: Hellmuth Hendrik; Hillringhaus Lars; Höbbel Sven; Kralj Slavko; Dijkhuizen Lubbert; Seibel Jürgen
Highly efficient chemoenzymatic synthesis of novel branched thiooligosaccharides by substrate direction with glucansucrases.
Chembiochem : a European journal of chemical biology 2007;8(3):273-6.
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2006: Yuan Xiao-Lian; Goosen Coenie; Kools Harrie; van der Maarel Marc J E C; van den Hondel Cees A M J J; Dijkhuizen Lubbert; Ram Arthur F J
Database mining and transcriptional analysis of genes encoding inulin-modifying enzymes of Aspergillus niger.
Microbiology (Reading, England) 2006;152(Pt 10):3061-73.
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2006: te Poele Evelien M; Kloosterman Harm; Hessels Gerda I; Bolhuis Henk; Dijkhuizen Lubbert
RepAM of the Amycolatopsis methanolica integrative element pMEA300 belongs to a novel class of replication initiator proteins.
Microbiology (Reading, England) 2006;152(Pt 10):2943-50.
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2006: Ozimek Lukasz K; Kralj Slavko; Kaper Thijs; van der Maarel Marc J E C; Dijkhuizen Lubbert
Single amino acid residue changes in subsite -1 of inulosucrase from Lactobacillus reuteri 121 strongly influence the size of products synthesized.
The FEBS journal 2006;273(17):4104-13.
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2006: Kralj Slavko; Eeuwema Wieger; Eckhardt Tom H; Dijkhuizen Lubbert
Role of asparagine 1134 in glucosidic bond and transglycosylation specificity of reuteransucrase from Lactobacillus reuteri 121.
The FEBS journal 2006;273(16):3735-42.
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2006: Claessen Dennis; de Jong Wouter; Dijkhuizen Lubbert; Wösten Han A B
Regulation of Streptomyces development: reach for the sky!
Trends in microbiology 2006;14(7):313-9.
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2006: Ozimek Lukasz K; Kralj Slavko; van der Maarel Marc J E C; Dijkhuizen Lubbert
The levansucrase and inulosucrase enzymes of Lactobacillus reuteri 121 catalyse processive and non-processive transglycosylation reactions.
Microbiology (Reading, England) 2006;152(Pt 4):1187-96.
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2006: van Hijum Sacha A F T; Kralj Slavko; Ozimek Lukasz K; Dijkhuizen Lubbert; van Geel-Schutten Ineke G H
Structure-function relationships of glucansucrase and fructansucrase enzymes from lactic acid bacteria.
Microbiology and molecular biology reviews : MMBR 2006;70(1):157-76.
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2006: Schoondermark-Stolk Sung A; Jansen Michael; Veurink Janine H; Verkleij Arie J; Verrips C Theo; Euverink Gert-Jan W; Boonstra Johannes; Dijkhuizen Lubbert
Rapid identification of target genes for 3-methyl-1-butanol production in Saccharomyces cerevisiae.
Applied microbiology and biotechnology 2006;70(2):237-46.
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2006: Malten Marco; Biedendieck Rebekka; Gamer Martin; Drews Ann-Christin; Stammen Simon; Buchholz Klaus; Dijkhuizen Lubbert; Jahn Dieter
A Bacillus megaterium plasmid system for the production, export, and one-step purification of affinity-tagged heterologous levansucrase from growth medium.
Applied and environmental microbiology 2006;72(2):1677-9.
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2005: Kaper Thijs; Talik Boguslawa; Ettema Thijs J; Bos Herman; van der Maarel Marc J E C; Dijkhuizen Lubbert
Amylomaltase of Pyrobaculum aerophilum IM2 produces thermoreversible starch gels.
Applied and environmental microbiology 2005;71(9):5098-106.
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2005: van Keulen Geertje; Hopwood David A; Dijkhuizen Lubbert; Sawers R Gary
Gas vesicles in actinomycetes: old buoys in novel habitats?
Trends in microbiology 2005;13(8):350-4.
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2005: Kralj S; Stripling E; Sanders P; van Geel-Schutten G H; Dijkhuizen L
Highly hydrolytic reuteransucrase from probiotic Lactobacillus reuteri strain ATCC 55730.
Applied and environmental microbiology 2005;71(7):3942-50.
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2005: Kralj Slavko; van Geel-Schutten Ineke G H; Faber Elly J; van der Maarel Marc J E C; Dijkhuizen Lubbert
Rational transformation of Lactobacillus reuteri 121 reuteransucrase into a dextransucrase.
Biochemistry 2005;44(25):9206-16.
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2005: Gebbink Martijn F B G; Claessen Dennis; Bouma Barend; Dijkhuizen Lubbert; Wösten Han A B
Amyloids--a functional coat for microorganisms.
Nature reviews. Microbiology 2005;3(4):333-41.
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2005: Ozimek L K; Euverink G J W; van der Maarel M J E C; Dijkhuizen L
Mutational analysis of the role of calcium ions in the Lactobacillus reuteri strain 121 fructosyltransferase (levansucrase and inulosucrase) enzymes.
FEBS letters 2005;579(5):1124-8.
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2004: Kralj S; van Geel-Schutten G H; Dondorff M M G; Kirsanovs S; van der Maarel M J E C; Dijkhuizen L
Glucan synthesis in the genus Lactobacillus: isolation and characterization of glucansucrase genes, enzymes and glucan products from six different strains.
Microbiology (Reading, England) 2004;150(Pt 11):3681-90.
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2004: Leemhuis Hans; Wehmeier Udo F; Dijkhuizen Lubbert
Single amino acid mutations interchange the reaction specificities of cyclodextrin glycosyltransferase and the acarbose-modifying enzyme acarviosyl transferase.
Biochemistry 2004;43(41):13204-13.
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2004: Kralj S; van Geel-Schutten G H; van der Maarel M J E C; Dijkhuizen L
Biochemical and molecular characterization of Lactobacillus reuteri 121 reuteransucrase.
Microbiology (Reading, England) 2004;150(Pt 7):2099-112.
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2004: Claessen Dennis; Stokroos Ietse; Deelstra Heine J; Penninga Nynke A; Bormann Christiane; Salas José A; Dijkhuizen Lubbert; Wösten Han A B
The formation of the rodlet layer of streptomycetes is the result of the interplay between rodlins and chaplins.
Molecular microbiology 2004;53(2):433-43.
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2004: van Keulen Geertje; Siebring Jeroen; Rembacz Krzysztof P; Hoogeveen Martin; Tomczynska Magdalena; Dijkhuizen Lubbert
Improved method for the isolation of RNA from (standing liquid cultures of) Streptomycetes.
Journal of microbiological methods 2004;58(1):139-42.
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2004: van der Geize Robert; Dijkhuizen Lubbert
Harnessing the catabolic diversity of rhodococci for environmental and biotechnological applications.
Current opinion in microbiology 2004;7(3):255-61.
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2004: Janssen M I; van Leeuwen M B M; van Kooten T G; de Vries J; Dijkhuizen L; Wösten H A B
Promotion of fibroblast activity by coating with hydrophobins in the beta-sheet end state.
Biomaterials 2004;25(14):2731-9.
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2004: Kaper T; van der Maarel M J E C; Euverink G J W; Dijkhuizen L
Exploring and exploiting starch-modifying amylomaltases from thermophiles.
Biochemical Society transactions 2004;32(Pt 2):279-82.
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2004: van Hijum S A F T; Szalowska E; van der Maarel M J E C; Dijkhuizen L
Biochemical and molecular characterization of a levansucrase from Lactobacillus reuteri.
Microbiology (Reading, England) 2004;150(Pt 3):621-30.
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2004: Ozimek L K; van Hijum S A F T; van Koningsveld G A; van Der Maarel M J E C; van Geel-Schutten G H; Dijkhuizen L
Site-directed mutagenesis study of the three catalytic residues of the fructosyltransferases of Lactobacillus reuteri 121.
FEBS letters 2004;560(1-3):131-3.
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2004: Leemhuis Hans; Rozeboom Henriëtte J; Dijkstra Bauke W; Dijkhuizen Lubbert
Improved thermostability of bacillus circulans cyclodextrin glycosyltransferase by the introduction of a salt bridge.
Proteins 2004;54(1):128-34.
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2004: Sosio Margherita; Kloosterman Harm; Bianchi Alessandra; de Vreugd Peter; Dijkhuizen Lubbert; Donadio Stefano
Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.
Microbiology (Reading, England) 2004;150(Pt 1):95-102.
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2003: Kloosterman H; Hessels G I; Vrijbloed J W; Euverink G J; Dijkhuizen L
(De)regulation of key enzyme steps in the shikimate pathway and phenylalanine-specific pathway of the actinomycete Amycolatopsis methanolica.
Microbiology (Reading, England) 2003;149(Pt 11):3321-30.
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2003: Leemhuis Hans; Euverink Gert-Jan W; Dijkhuizen Lubbert
High-throughput screening for gene libraries expressing carbohydrate hydrolase activity.
Biotechnology letters 2003;25(19):1643-5.
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2003: Leemhuis Hans; Kragh Karsten M; Dijkstra Bauke W; Dijkhuizen Lubbert
Engineering cyclodextrin glycosyltransferase into a starch hydrolase with a high exo-specificity.
Journal of biotechnology 2003;103(3):203-12.
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2003: Claessen Dennis; Rink Rick; de Jong Wouter; Siebring Jeroen; de Vreugd Peter; Boersma F G Hidde; Dijkhuizen Lubbert; Wosten Han A B
A novel class of secreted hydrophobic proteins is involved in aerial hyphae formation in Streptomyces coelicolor by forming amyloid-like fibrils.
Genes & development 2003;17(14):1714-26.
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2003: Leemhuis Hans; Rozeboom Henriëtte J; Wilbrink Maarten; Euverink Gert-Jan W; Dijkstra Bauke W; Dijkhuizen Lubbert
Conversion of cyclodextrin glycosyltransferase into a starch hydrolase by directed evolution: the role of alanine 230 in acceptor subsite +1.
Biochemistry 2003;42(24):7518-26.
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2003: Jansen Michael; Veurink Janine H; Euverink Gert-Jan W; Dijkhuizen Lubbert
Growth of the salt-tolerant yeast Zygosaccharomyces rouxii in microtiter plates: effects of NaCl, pH and temperature on growth and fusel alcohol production from branched-chain amino acids.
FEMS yeast research 2003;3(3):313-8.
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2003: Leemhuis Hans; Rozeboom Henriëtte J; Dijkstra Bauke W; Dijkhuizen Lubbert
The fully conserved Asp residue in conserved sequence region I of the alpha-amylase family is crucial for the catalytic site architecture and activity.
FEBS letters 2003;541(1-3):47-51.
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2003: van Keulen Geertje; Jonkers Henk M; Claessen Dennis; Dijkhuizen Lubbert; Wösten Han A B
Differentiation and anaerobiosis in standing liquid cultures of Streptomyces coelicolor.
Journal of bacteriology 2003;185(4):1455-8.
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2003: van Keulen Geertje; Ridder Anja N J A; Dijkhuizen Lubbert; Meijer Wim G
Analysis of DNA binding and transcriptional activation by the LysR-type transcriptional regulator CbbR of Xanthobacter flavus.
Journal of bacteriology 2003;185(4):1245-52.
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2003: van Hijum S A F T; van der Maarel M J E C; Dijkhuizen L
Kinetic properties of an inulosucrase from Lactobacillus reuteri 121.
FEBS letters 2003;534(1-3):207-10.
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2003: Leemhuis Hans; Dijkstra Bauke W; Dijkhuizen Lubbert
Thermoanaerobacterium thermosulfurigenes cyclodextrin glycosyltransferase.
European journal of biochemistry / FEBS 2003;270(1):155-62.
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2002: Janssen M I; van Leeuwen M B M; Scholtmeijer K; van Kooten T G; Dijkhuizen L; Wösten H A B
Coating with genetic engineered hydrophobin promotes growth of fibroblasts on a hydrophobic solid.
Biomaterials 2002;23(24):4847-54.
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2002: Hektor Harm J; Kloosterman Harm; Dijkhuizen Lubbert
Identification of a magnesium-dependent NAD(P)(H)-binding domain in the nicotinoprotein methanol dehydrogenase from Bacillus methanolicus.
The Journal of biological chemistry 2002;277(49):46966-73.
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2002: van der Geize Robert; Hessels Gerda I; Dijkhuizen Lubbert
Molecular and functional characterization of the kstD2 gene of Rhodococcus erythropolis SQ1 encoding a second 3-ketosteroid Delta(1)-dehydrogenase isoenzyme.
Microbiology (Reading, England) 2002;148(Pt 10):3285-92.
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2002: van Hijum S A F T; van Geel-Schutten G H; Rahaoui H; van der Maarel M J E C; Dijkhuizen L
Characterization of a novel fructosyltransferase from Lactobacillus reuteri that synthesizes high-molecular-weight inulin and inulin oligosaccharides.
Applied and environmental microbiology 2002;68(9):4390-8.
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2002: Kralj S; van Geel-Schutten G H; Rahaoui H; Leer R J; Faber E J; van der Maarel M J E C; Dijkhuizen L
Molecular characterization of a novel glucosyltransferase from Lactobacillus reuteri strain 121 synthesizing a unique, highly branched glucan with alpha-(1-->4) and alpha-(1-->6) glucosidic bonds.
Applied and environmental microbiology 2002;68(9):4283-91.
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2002: Kloosterman Harm; Vrijbloed Jan W; Dijkhuizen Lubbert
Molecular, biochemical, and functional characterization of a Nudix hydrolase protein that stimulates the activity of a nicotinoprotein alcohol dehydrogenase.
The Journal of biological chemistry 2002;277(38):34785-92.
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2002: van der Geize R; Hessels G I; van Gerwen R; van der Meijden P; Dijkhuizen L
Molecular and functional characterization of kshA and kshB, encoding two components of 3-ketosteroid 9alpha-hydroxylase, a class IA monooxygenase, in Rhodococcus erythropolis strain SQ1.
Molecular microbiology 2002;45(4):1007-18.
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2002: Claessen Dennis; Wösten Han A B; van Keulen Geertje; Faber Onno G; Alves Alexandra M C R; Meijer Wim G; Dijkhuizen Lubbert
Two novel homologous proteins of Streptomyces coelicolor and Streptomyces lividans are involved in the formation of the rodlet layer and mediate attachment to a hydrophobic surface.
Molecular microbiology 2002;44(6):1483-92.
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2002: Leemhuis Hans; Dijkstra Bauke W; Dijkhuizen Lubbert
Mutations converting cyclodextrin glycosyltransferase from a transglycosylase into a starch hydrolase.
FEBS letters 2002;514(2-3):189-92.
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2002: van der Maarel Marc J E C; van der Veen Bart; Uitdehaag Joost C M; Leemhuis Hans; Dijkhuizen L
Properties and applications of starch-converting enzymes of the alpha-amylase family.
Journal of biotechnology 2002;94(2):137-55.
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2002: Leemhuis Hans; Uitdehaag Joost C M; Rozeboom Henriette J; Dijkstra Bauke W; Dijkhuizen Lubbert
The remote substrate binding subsite -6 in cyclodextrin-glycosyltransferase controls the transferase activity of the enzyme via an induced-fit mechanism.
The Journal of biological chemistry 2002;277(2):1113-9.
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2001: van Hijum S A; Bonting K; van der Maarel M J; Dijkhuizen L
Purification of a novel fructosyltransferase from Lactobacillus reuteri strain 121 and characterization of the levan produced.
FEMS microbiology letters 2001;205(2):323-8.
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2001: van der Geize R; Hessels G I; van Gerwen R; van der Meijden P; Dijkhuizen L
Unmarked gene deletion mutagenesis of kstD, encoding 3-ketosteroid Delta1-dehydrogenase, in Rhodococcus erythropolis SQ1 using sacB as counter-selectable marker.
FEMS microbiology letters 2001;205(2):197-202.
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2001: Alves A M; Euverink G J; Santos H; Dijkhuizen L
Different physiological roles of ATP- and PP(i)-dependent phosphofructokinase isoenzymes in the methylotrophic actinomycete Amycolatopsis methanolica.
Journal of bacteriology 2001;183(24):7231-40.
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2001: van der Veen B A; Leemhuis H; Kralj S; Uitdehaag J C; Dijkstra B W; Dijkhuizen L
Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase.
The Journal of biological chemistry 2001;276(48):44557-62.
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2001: Uitdehaag J C; van der Veen B A; Dijkhuizen L; Elber R; Dijkstra B W
Enzymatic circularization of a malto-octaose linear chain studied by stochastic reaction path calculations on cyclodextrin glycosyltransferase.
Proteins 2001;43(3):327-35.
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2000: van der Veen BA; Uitdehaag J C; Dijkstra B W; Dijkhuizen L
Engineering of cyclodextrin glycosyltransferase reaction and product specificity.
Biochimica et biophysica acta 2000;1543(2):336-360.
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2000: van Keulen G; Dijkhuizen L; Meijer W G
Effects of the Calvin cycle on nicotinamide adenine dinucleotide concentrations and redox balances of Xanthobacter flavus.
Journal of bacteriology 2000;182(16):4637-9.
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2000: Uitdehaag J C; van Alebeek G J; van Der Veen B A; Dijkhuizen L; Dijkstra B W
Structures of maltohexaose and maltoheptaose bound at the donor sites of cyclodextrin glycosyltransferase give insight into the mechanisms of transglycosylation activity and cyclodextrin size specificity.
Biochemistry 2000;39(26):7772-80.
-
2000: van der Veen B A; Uitdehaag J C; Dijkstra B W; Dijkhuizen L
The role of arginine 47 in the cyclization and coupling reactions of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 implications for product inhibition and product specificity.
European journal of biochemistry / FEBS 2000;267(12):3432-41.
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2000: van Der Geize R; Hessels G I; van Gerwen R; Vrijbloed J W; van Der Meijden P; Dijkhuizen L
Targeted disruption of the kstD gene encoding a 3-ketosteroid delta(1)-dehydrogenase isoenzyme of Rhodococcus erythropolis strain SQ1.
Applied and environmental microbiology 2000;66(5):2029-36.
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2000: van der Veen B A; Uitdehaag J C; Penninga D; van Alebeek G J; Smith L M; Dijkstra B W; Dijkhuizen L
Rational design of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 to increase alpha-cyclodextrin production.
Journal of molecular biology 2000;296(4):1027-38.
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2000: van der Veen B A; van Alebeek G J; Uitdehaag J C; Dijkstra B W; Dijkhuizen L
The three transglycosylation reactions catalyzed by cyclodextrin glycosyltransferase from Bacillus circulans (strain 251) proceed via different kinetic mechanisms.
European journal of biochemistry / FEBS 2000;267(3):658-65.
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1999: Uitdehaag J C; Kalk K H; van Der Veen B A; Dijkhuizen L; Dijkstra B W
The cyclization mechanism of cyclodextrin glycosyltransferase (CGTase) as revealed by a gamma-cyclodextrin-CGTase complex at 1.8-A resolution.
The Journal of biological chemistry 1999;274(49):34868-76.
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1999: Uitdehaag J C; Mosi R; Kalk K H; van der Veen B A; Dijkhuizen L; Withers S G; Dijkstra B W
X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family.
Nature structural biology 1999;6(5):432-6.
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1998: Breedveld M; Bonting K; Dijkhuizen L
Mutational analysis of exopolysaccharide biosynthesis by Lactobacillus sakei 0-1.
FEMS microbiology letters 1998;169(2):241-9.
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1998: Wind R D; Buitelaar R M; Dijkhuizen L
Engineering of factors determining alpha-amylase and cyclodextrin glycosyltransferase specificity in the cyclodextrin glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1.
European journal of biochemistry / FEBS 1998;253(3):598-605.
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1998: van Keulen G; Girbal L; van den Bergh E R; Dijkhuizen L; Meijer W G
The LysR-type transcriptional regulator CbbR controlling autotrophic CO2 fixation by Xanthobacter flavus is an NADPH sensor.
Journal of bacteriology 1998;180(6):1411-7.
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1998: Wind R D; Uitdehaag J C; Buitelaar R M; Dijkstra B W; Dijkhuizen L
Engineering of cyclodextrin product specificity and pH optima of the thermostable cyclodextrin glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1.
The Journal of biological chemistry 1998;273(10):5771-9.
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1997: Bystrykh L V; Govorukhina N I; Dijkhuizen L; Duine J A
Tetrazolium-dye-linked alcohol dehydrogenase of the methylotrophic actinomycete Amycolatopsis methanolica is a three-component complex.
European journal of biochemistry / FEBS 1997;247(1):280-7.
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1997: Arfman N; Hektor H J; Bystrykh L V; Govorukhina N I; Dijkhuizen L; Frank J
Properties of an NAD(H)-containing methanol dehydrogenase and its activator protein from Bacillus methanolicus.
European journal of biochemistry / FEBS 1997;244(2):426-33.
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1997: Alves A M; Euverink G J; Bibb M J; Dijkhuizen L
Identification of ATP-dependent phosphofructokinase as a regulatory step in the glycolytic pathway of the actinomycete Streptomyces coelicolor A3(2).
Applied and environmental microbiology 1997;63(3):956-61.
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1996: Penninga D; van der Veen B A; Knegtel R M; van Hijum S A; Rozeboom H J; Kalk K H; Dijkstra B W; Dijkhuizen L
The raw starch binding domain of cyclodextrin glycosyltransferase from Bacillus circulans strain 251.
The Journal of biological chemistry 1996;271(51):32777-84.
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1996: Strokopytov B; Knegtel R M; Penninga D; Rozeboom H J; Kalk K H; Dijkhuizen L; Dijkstra B W
Structure of cyclodextrin glycosyltransferase complexed with a maltononaose inhibitor at 2.6 angstrom resolution. Implications for product specificity.
Biochemistry 1996;35(13):4241-9.
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1996: Bystrykh L V; Fernández-Moreno M A; Herrema J K; Malpartida F; Hopwood D A; Dijkhuizen L
Production of actinorhodin-related "blue pigments" by Streptomyces coelicolor A3(2).
Journal of bacteriology 1996;178(8):2238-44.
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1996: Smith L M; Meijer W G; Dijkhuizen L; Goodwin P M
A protein having similarity with methylmalonyl-CoA mutase is required for the assimilation of methanol and ethanol by Methylobacterium extorquens AM1.
Microbiology (Reading, England) 1996;142 ( Pt 3)():675-84.
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1996: Knegtel R M; Wind R D; Rozeboom H J; Kalk K H; Buitelaar R M; Dijkhuizen L; Dijkstra B W
Crystal structure at 2.3 A resolution and revised nucleotide sequence of the thermostable cyclodextrin glycosyltransferase from Thermonanaerobacterium thermosulfurigenes EM1.
Journal of molecular biology 1996;256(3):611-22.
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1996: van den Bergh E R; Baker S C; Raggers R J; Terpstra P; Woudstra E C; Dijkhuizen L; Meijer W G
Primary structure and phylogeny of the Calvin cycle enzymes transketolase and fructosebisphosphate aldolase of Xanthobacter flavus.
Journal of bacteriology 1996;178(3):888-93.
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1996: Alves A M; Meijer W G; Vrijbloed J W; Dijkhuizen L
Characterization and phylogeny of the pfp gene of Amycolatopsis methanolica encoding PPi-dependent phosphofructokinase.
Journal of bacteriology 1996;178(1):149-55.
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1995: Knegtel R M; Strokopytov B; Penninga D; Faber O G; Rozeboom H J; Kalk K H; Dijkhuizen L; Dijkstra B W
Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products.
The Journal of biological chemistry 1995;270(49):29256-64.
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1995: Euverink G J; Hessels G I; Franke C; Dijkhuizen L
Chorismate mutase and 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of the methylotrophic actinomycete Amycolatopsis methanolica.
Applied and environmental microbiology 1995;61(11):3796-803.
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1995: Vrijbloed J W; van Hylckama Vlieg J; van der Put N M; Hessels G I; Dijkhuizen L
Molecular cloning with a pMEA300-derived shuttle vector and characterization of the Amycolatopsis methanolica prephenate dehydratase gene.
Journal of bacteriology 1995;177(22):6666-9.
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1995: Vrijbloed J W; van der Put N M; Dijkhuizen L
Identification and functional analysis of the transfer region of plasmid pMEA300 of the methylotrophic actinomycete Amycolatopsis methanolica.
Journal of bacteriology 1995;177(22):6499-505.
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1995: Vrijbloed J W; Jelínková M; Hessels G I; Dijkhuizen L
Identification of the minimal replicon of plasmid pMEA300 of the methylotrophic actinomycete Amycolatopsis methanolica.
Molecular microbiology 1995;18(1):21-31.
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1995: van den Bergh E R; van der Kooij T A; Dijkhuizen L; Meijer W G
Fructosebisphosphatase isoenzymes of the chemoautotroph Xanthobacter flavus.
Journal of bacteriology 1995;177(20):5860-4.
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1995: Vrijbloed J W; Madon J; Dijkhuizen L
Transformation of the methylotrophic actinomycete Amycolatopis methanolica with plasmid DNA: stimulatory effect of a pMEA300-encoded gene.
Plasmid 1995;34(2):96-104.
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1995: Euverink G J; Wolters D J; Dijkhuizen L
Prephenate dehydratase of the actinomycete Amycolatopsis methanolica: purification and characterization of wild-type and deregulated mutant proteins.
The Biochemical journal 1995;308 ( Pt 1)():313-20.
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1995: Wind R D; Liebl W; Buitelaar R M; Penninga D; Spreinat A; Dijkhuizen L; Bahl H
Cyclodextrin formation by the thermostable alpha-amylase of Thermoanaerobacterium thermosulfurigenes EM1 and reclassification of the enzyme as a cyclodextrin glycosyltransferase.
Applied and environmental microbiology 1995;61(4):1257-65.
-
1995: Penninga D; Strokopytov B; Rozeboom H J; Lawson C L; Dijkstra B W; Bergsma J; Dijkhuizen L
Site-directed mutations in tyrosine 195 of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 affect activity and product specificity.
Biochemistry 1995;34(10):3368-76.
-
1995: Strokopytov B; Penninga D; Rozeboom H J; Kalk K H; Dijkhuizen L; Dijkstra B W
X-ray structure of cyclodextrin glycosyltransferase complexed with acarbose. Implications for the catalytic mechanism of glycosidases.
Biochemistry 1995;34(7):2234-40.
-
1994: Vrijbloed J W; Madon J; Dijkhuizen L
A plasmid from the methylotrophic actinomycete Amycolatopsis methanolica capable of site-specific integration.
Journal of bacteriology 1994;176(22):7087-90.
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1994: Alves A M; Euverink G J; Hektor H J; Hessels G I; van der Vlag J; Vrijbloed J W; Hondmann D; Visser J; Dijkhuizen L
Enzymes of glucose and methanol metabolism in the actinomycete Amycolatopsis methanolica.
Journal of bacteriology 1994;176(22):6827-35.
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1994: Lawson C L; van Montfort R; Strokopytov B; Rozeboom H J; Kalk K H; de Vries G E; Penninga D; Dijkhuizen L; Dijkstra B W
Nucleotide sequence and X-ray structure of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 in a maltose-dependent crystal form.
Journal of molecular biology 1994;236(2):590-600.
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1993: van den Bergh E R; Dijkhuizen L; Meijer W G
CbbR, a LysR-type transcriptional activator, is required for expression of the autotrophic CO2 fixation enzymes of Xanthobacter flavus.
Journal of bacteriology 1993;175(19):6097-104.
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1993: Bystrykh L V; Vonck J; van Bruggen E F; van Beeumen J; Samyn B; Govorukhina N I; Arfman N; Duine J A; Dijkhuizen L
Electron microscopic analysis and structural characterization of novel NADP(H)-containing methanol: N,N'-dimethyl-4-nitrosoaniline oxidoreductases from the gram-positive methylotrophic bacteria Amycolatopsis methanolica and Mycobacterium gastri MB19.
Journal of bacteriology 1993;175(6):1814-22.
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1992: Tabita F R; Gibson J L; Bowien B; Dijkhuizen L; Meijer W G
Uniform designation for genes of the Calvin-Benson-Bassham reductive pentose phosphate pathway of bacteria.
FEMS microbiology letters 1992;78(2-3):107-10.
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1992: Euverink G J; Hessels G I; Vrijbloed J W; Coggins J R; Dijkhuizen L
Purification and characterization of a dual function 3-dehydroquinate dehydratase from Amycolatopsis methanolica.
Journal of general microbiology 1992;138(11):2449-57.
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1992: Attwood M M; Arfman N; Weusthuis R A; Dijkhuizen L
Purification and characterization of an NAD(+)-linked formaldehyde dehydrogenase from the facultative RuMP cycle methylotroph Arthrobacter P1.
Antonie van Leeuwenhoek 1992;62(3):201-7.
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1992: de Vries G E; Arfman N; Terpstra P; Dijkhuizen L
Cloning, expression, and sequence analysis of the Bacillus methanolicus C1 methanol dehydrogenase gene.
Journal of bacteriology 1992;174(16):5346-53.
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1992: Arfman N; Dijkhuizen L; Kirchhof G; Ludwig W; Schleifer K H; Bulygina E S; Chumakov K M; Govorukhina N I; Trotsenko Y A; White D
Bacillus methanolicus sp. nov., a new species of thermotolerant, methanol-utilizing, endospore-forming bacteria.
International journal of systematic bacteriology 1992;42(3):439-45.
-
1992: Reding H K; Croes G L; Dijkhuizen L; Wiegel J
Emendation of Xanthobacter flavus as a motile species.
International journal of systematic bacteriology 1992;42(2):309-11.
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1992: Arfman N; de Vries K J; Moezelaar H R; Attwood M M; Robinson G K; van Geel M; Dijkhuizen L
Environmental regulation of alcohol metabolism in thermotolerant methylotrophic Bacillus strains.
Archives of microbiology 1992;157(3):272-8.
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1991: Bystrykh L V; Dijkhuizen L; Harder W
Modification of flavin adenine dinucleotide in alcohol oxidase of the yeast Hansenula polymorpha.
Journal of general microbiology 1991;137(10):2381-6.
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1991: Arfman N; Van Beeumen J; De Vries G E; Harder W; Dijkhuizen L
Purification and characterization of an activator protein for methanol dehydrogenase from thermotolerant Bacillus spp.
The Journal of biological chemistry 1991;266(6):3955-60.
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1991: Vonck J; Arfman N; De Vries G E; Van Beeumen J; Van Bruggen E F; Dijkhuizen L
Electron microscopic analysis and biochemical characterization of a novel methanol dehydrogenase from the thermotolerant Bacillus sp. C1.
The Journal of biological chemistry 1991;266(6):3949-54.
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1991: Meijer W G; Arnberg A C; Enequist H G; Terpstra P; Lidstrom M E; Dijkhuizen L
Identification and organization of carbon dioxide fixation genes in Xanthobacter flavus H4-14.
Molecular & general genetics : MGG 1991;225(2):320-30.
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1990: Meijer W G; Enequist H G; Terpstra P; Dijkhuizen L
Nucleotide sequences of the genes encoding fructosebisphosphatase and phosphoribulokinase from Xanthobacter flavus H4-14.
Journal of general microbiology 1990;136(11):2225-30.
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1990: Lawson C L; Bergsma J; Bruinenberg P M; de Vries G; Dijkhuizen L; Dijkstra B W
Maltodextrin-dependent crystallization of cyclomaltodextrin glucanotransferase from Bacillus circulans.
Journal of molecular biology 1990;214(4):807-9.
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1990: de Boer L; Dijkhuizen L; Grobben G; Goodfellow M; Stackebrandt E; Parlett J H; Whitehead D; Witt D
Amycolatopsis methanolica sp. nov., a facultatively methylotrophic actinomycete.
International journal of systematic bacteriology 1990;40(2):194-204.
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1990: Meijer W G; Croes L M; Jenni B; Lehmicke L G; Lidstrom M E; Dijkhuizen L
Characterization of Xanthobacter strains H4-14 and 25a and enzyme profiles after growth under autotrophic and heterotrophic conditions.
Archives of microbiology 1990;153(4):360-7.
-
1990: Arfman N; Bystrykh L; Govorukhina N I; Dijkhuizen L
3-Hexulose-6-phosphate synthase from thermotolerant methylotroph Bacillus C1.
Methods in enzymology 1990;188():391-7.
-
1990: Arfman N; Dijkhuizen L
Methanol dehydrogenase from thermotolerant methylotroph Bacillus C1.
Methods in enzymology 1990;188():223-6.
-
1989: De Boer L; Brouwer J W; Van Hassel C W; Levering P R; Dijkhuizen L
Nitrogen metabolism in the facultative methylotroph Arthrobacter P1 grown with various amines or ammonia as nitrogen sources.
Antonie van Leeuwenhoek 1989;56(3):221-32.
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1989: Arfman N; Watling E M; Clement W; van Oosterwijk R J; de Vries G E; Harder W; Attwood M M; Dijkhuizen L
Methanol metabolism in thermotolerant methylotrophic Bacillus strains involving a novel catabolic NAD-dependent methanol dehydrogenase as a key enzyme.
Archives of microbiology 1989;152(3):280-8.
-
1988: Meijer W G; Dijkhuizen L
Regulation of autotrophic metabolism in Pseudomonas oxalaticus OX1 wild-type and an isocitrate-lyase-deficient mutant.
Journal of general microbiology 1988;134(12):3231-7.
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1985: Janssen D B; Scheper A; Dijkhuizen L; Witholt B
Degradation of halogenated aliphatic compounds by Xanthobacter autotrophicus GJ10.
Applied and environmental microbiology 1985;49(3):673-7.
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1984: Dijkhuizen L; Harder W; de Boer L; van Boven A; Clement W; Bron S; Venema G
Genetic manipulation of the restricted facultative methylotroph Hyphomicrobium X by the R-plasmid-mediated introduction of the Escherichia coli pdh genes.
Archives of microbiology 1984;139(4):311-8.
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1984: Dijkhuizen L; Harder W
Current views on the regulation of autotrophic carbon dioxide fixation via the Calvin cycle in bacteria.
Antonie van Leeuwenhoek 1984;50(5-6):473-87.
-
1983: Harder W; Dijkhuizen L
Physiological responses to nutrient limitation.
Annual review of microbiology 1983;37():1-23.
-
1982: Harder W; Dijkhuizen L
Strategies of mixed substrate utilization in microorganisms.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1982;297(1088):459-80.
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1978: Dijkhuizen L; Knight M; Harder W
Metabolic regulation in Pseudomonas oxalaticus OX1. Autotrophic and heterotrophic growth on mixed substrates.
Archives of microbiology 1978;116(1):77-83.
-
1978: Knight M; Dijkhuizen L; Harder W
Metabolic regulation in Pseudomonas oxalaticus OX1. Enzyme and coenzyme concentration changes during substrate transition experiments.
Archives of microbiology 1978;116(1):85-90.
-
1977: Dijkhuizen L; Wiersma M; Harder W
Energy production and growth of Pseudomonas oxalaticus OX1 on oxalate and formate.
Archives of microbiology 1977;115(2):229-36.
-
1977: Dijkhuizen L; Groen L; Harder W; Konings W N
Active transport of oxalate by Pseudomonas oxalaticus OX1.
Archives of microbiology 1977;115(2):223-7.
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1975: Dijkhuizen L; Harder W
Substrate inhibition in Pseudomonas oxalaticus OX1: a kinetic study of growth inhibition by oxalate and formate using extended cultures.
Antonie van Leeuwenhoek 1975;41(2):135-46.
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