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Nigel Cairns

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
69
Lubec, Gert
49
Armstrong, Richard
37
Lantos, Peter
17
Fountoulakis, Michael
16
Seidl, Rainer
14
förstl, hans
14
Bigio, Eileen
14
Labudova, O
14
Rossor, Martin
13
Lantos, Peter
12
Rubinsztein, David
11
Perry, Robert
11
Morris, John
10
Mackenzie, Ian
10
Kim, Seong Hwan

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Publications

TOP 3
Wegorzewska Iga; Bell Shaughn; Cairns Nigel J; Miller Timothy M; Baloh Robert H
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration.
Gitcho Michael A; Bigio Eileen H; Mishra Manjari; Johnson Nancy; Weintraub Sandra; Mesulam Marsel; Rademakers Rosa; Chakraverty Sumi; Cruchaga Carlos; Morris John C; Goate Alison M; Cairns Nigel J
TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy.
Armstrong R A; Cairns N J
Laminar distribution of the pathological changes in frontal and temporal cortex in 8 patients with progressive supranuclear palsy.

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All Publications

2009: Wegorzewska Iga; Bell Shaughn; Cairns Nigel J; Miller Timothy M; Baloh Robert H
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18809-14.
2009: Gitcho Michael A; Bigio Eileen H; Mishra Manjari; Johnson Nancy; Weintraub Sandra; Mesulam Marsel; Rademakers Rosa; Chakraverty Sumi; Cruchaga Carlos; Morris John C; Goate Alison M; Cairns Nigel J
TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy.
Acta neuropathologica 2009;118(5):633-45.
2009: Armstrong R A; Cairns N J
Laminar distribution of the pathological changes in frontal and temporal cortex in 8 patients with progressive supranuclear palsy.
Clinical neuropathology 2009;28(5):350-7.
2009: Armstrong R A; Cairns N J
Clustering and spatial correlations of the neuronal cytoplasmic inclusions, astrocytic plaques and ballooned neurons in corticobasal degeneration.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(9):1103-10.
2009: Norton J B; Cairns N J; Chakraverty S; Wang J; Levitch D; Galvin J E; Goate A
Presenilin1 G217R mutation linked to Alzheimer disease with cotton wool plaques.
Neurology 2009;73(6):480-2.
2009: Gitcho Michael A; Strider Jeffrey; Carter Deborah; Taylor-Reinwald Lisa; Forman Mark S; Goate Alison M; Cairns Nigel J
VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death.
The Journal of biological chemistry 2009;284(18):12384-98.
2009: Rollinson Sara; Rizzu Patrizia; Sikkink Stephen; Baker Matthew; Halliwell Nicola; Snowden Julie; Traynor Bryan J; Ruano Dina; Cairns Nigel; Rohrer Jonathan D; Mead Simon; Collinge John; Rossor Martin; Akay Ela; Guerreiro Rita; Rademakers Rosa; Morrison Karen E; Pastor Pau; Alonso Elena; Martinez-Lage Pablo; Graff-Radford Neil; Neary David; Heutink Peter; Mann David M A; Van Swieten John; Pickering-Brown Stuart M
Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration.
Neurobiology of aging 2009;30(4):656-65.
2009: Armstrong R A; Ironside J W; Lantos P L; Cairns N J
A quantitative study of the pathological changes in the cerebellum in 15 cases of variant Creutzfeldt-Jakob disease (vCJD).
Neuropathology and applied neurobiology 2009;35(1):36-45.
2009: Armstrong R A; Lantos P L; Cairns N J
Hippocampal pathology in progressive supranuclear palsy (PSP): a quantitative study of 8 cases.
Clinical neuropathology 2009;28(1):46-53.
2009: Mackenzie Ian R A; Neumann Manuela; Bigio Eileen H; Cairns Nigel J; Alafuzoff Irina; Kril Jillian; Kovacs Gabor G; Ghetti Bernardino; Halliday Glenda; Holm Ida E; Ince Paul G; Kamphorst Wouter; Revesz Tamas; Rozemuller Annemieke J M; Kumar-Singh Samir; Akiyama Haruhiko; Baborie Atik; Spina Salvatore; Dickson Dennis W; Trojanowski John Q; Mann David M A
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations.
Acta neuropathologica 2009;117(1):15-8.
2008: Thorpe Julian R; Tang Helen; Atherton Joe; Cairns Nigel J
Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(12):1661-71.
2008: Liscic R M; Grinberg L T; Zidar J; Gitcho M A; Cairns N J
ALS and FTLD: two faces of TDP-43 proteinopathy.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2008;15(8):772-80.
2008: Armstrong Richard A; Lantos Peter L; Cairns Nigel J
What determines the molecular composition of abnormal protein aggregates in neurodegenerative disease?
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(4):351-65.
2008: Tang X N; Cairns B; Cairns N; Yenari M A
Apocynin improves outcome in experimental stroke with a narrow dose range.
Neuroscience 2008;154(2):556-62.
2008: Roe Catherine M; Xiong Chengjie; Miller J Phillip; Cairns Nigel J; Morris John C
Interaction of neuritic plaques and education predicts dementia.
Alzheimer disease and associated disorders 2008;22(2):188-93.
2008: Hatanpaa Kimmo J; Bigio Eileen H; Cairns Nigel J; Womack Kyle B; Weintraub Sandra; Morris John C; Foong Chan; Xiao Guanghua; Hladik Christa; Mantanona Tina Y; White Charles L
TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study.
Journal of neuropathology and experimental neurology 2008;67(4):271-9.
2008: Gitcho Michael A; Baloh Robert H; Chakraverty Sumi; Mayo Kevin; Norton Joanne B; Levitch Denise; Hatanpaa Kimmo J; White Charles L; Bigio Eileen H; Caselli Richard; Baker Matt; Al-Lozi Muhammad T; Morris John C; Pestronk Alan; Rademakers Rosa; Goate Alison M; Cairns Nigel J
TDP-43 A315T mutation in familial motor neuron disease.
Annals of neurology 2008;63(4):535-8.
2008: Mukherjee Odity; Wang Jun; Gitcho Michael; Chakraverty Sumi; Taylor-Reinwald Lisa; Shears Shantia; Kauwe John S K; Norton Joanne; Levitch Denise; Bigio Eileen H; Hatanpaa Kimmo J; White Charles L; Morris John C; Cairns Nigel J; Goate Alison
Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia.
Human mutation 2008;29(4):512-21.
2008: Li Yonghong; Grupe Andrew; Rowland Charles; Holmans Peter; Segurado Ricardo; Abraham Richard; Jones Lesley; Catanese Joseph; Ross David; Mayo Kevin; Martinez Maribel; Hollingworth Paul; Goate Alison; Cairns Nigel J; Racette Brad A; Perlmutter Joel S; O'Donovan Michael C; Morris John C; Brayne Carol; Rubinsztein David C; Lovestone Simon; Thal Leon J; Owen Michael J; Williams Julie
Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Human molecular genetics 2008;17(5):759-67.
2008: Wippold F J; Cairns N; Vo K; Holtzman D M; Morris J C
Neuropathology for the neuroradiologist: plaques and tangles.
AJNR. American journal of neuroradiology 2008;29(1):18-22.
2008: Cairns Nigel J
Neuronal intermediate filament inclusion disease.
Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn 2008;89():443-8.
2007: Cairns Nigel J; Neumann Manuela; Bigio Eileen H; Holm Ida E; Troost Dirk; Hatanpaa Kimmo J; Foong Chan; White Charles L; Schneider Julie A; Kretzschmar Hans A; Carter Deborah; Taylor-Reinwald Lisa; Paulsmeyer Katherine; Strider Jeffrey; Gitcho Michael; Goate Alison M; Morris John C; Mishra Manjari; Kwong Linda K; Stieber Anna; Xu Yan; Forman Mark S; Trojanowski John Q; Lee Virginia M-Y; Mackenzie Ian R A
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
The American journal of pathology 2007;171(1):227-40.
2007: Cairns Nigel J; Bigio Eileen H; Mackenzie Ian R A; Neumann Manuela; Lee Virginia M-Y; Hatanpaa Kimmo J; White Charles L; Schneider Julie A; Grinberg Lea Tenenholz; Halliday Glenda; Duyckaerts Charles; Lowe James S; Holm Ida E; Tolnay Markus; Okamoto Koichi; Yokoo Hideaki; Murayama Shigeo; Woulfe John; Munoz David G; Dickson Dennis W; Ince Paul G; Trojanowski John Q; Mann David M A;
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Acta neuropathologica 2007;114(1):5-22.
2007: Armstrong Richard A; Cairns Nigel J; Lantos Peter L
A quantitative study of the pathological changes in white matter in multiple system atrophy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2007;27(3):221-7.
2007: Mackenzie Ian R A; Bigio Eileen H; Ince Paul G; Geser Felix; Neumann Manuela; Cairns Nigel J; Kwong Linda K; Forman Mark S; Ravits John; Stewart Heather; Eisen Andrew; McClusky Leo; Kretzschmar Hans A; Monoranu Camelia M; Highley J Robin; Kirby Janine; Siddique Teepu; Shaw Pamela J; Lee Virginia M-Y; Trojanowski John Q
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Annals of neurology 2007;61(5):427-34.
2007: Liscic Rajka M; Storandt Martha; Cairns Nigel J; Morris John C
Clinical and psychometric distinction of frontotemporal and Alzheimer dementias.
Archives of neurology 2007;64(4):535-40.
2007: Neumann Manuela; Mackenzie Ian R; Cairns Nigel J; Boyer Philip J; Markesbery William R; Smith Charles D; Taylor J Paul; Kretzschmar Hans A; Kimonis Virginia E; Forman Mark S
TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations.
Journal of neuropathology and experimental neurology 2007;66(2):152-7.
2007: Armstrong Richard A; Lantos Peter L; Cairns Nigel J
Spatial topography of the neurofibrillary tangles in cortical and subcortical regions in progressive supranuclear palsy.
Parkinsonism & related disorders 2007;13(1):50-4.
2007: Behrens Maria I; Mukherjee Odity; Tu Pang-hsien; Liscic Rajka M; Grinberg Lea Tenenholz; Carter Deborah; Paulsmeyer Katherine; Taylor-Reinwald Lisa; Gitcho Michael; Norton Joanne B; Chakraverty Sumi; Goate Alison M; Morris John C; Cairns Nigel J
Neuropathologic heterogeneity in HDDD1: a familial frontotemporal lobar degeneration with ubiquitin-positive inclusions and progranulin mutation.
Alzheimer disease and associated disorders 2007;21(1):1-7.
2007: Armstrong R A; Lantos P L; Cairns N J
Progressive supranuclear palsy (PSP): a quantitative study of the pathological changes in cortical and subcortical regions of eight cases.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(12):1569-77.
2007: Armstrong R A; Cairns N J
Spatial patterns of the pathological changes in neuronal intermediate filament inclusion disease (NIFID): an alpha-internexin immunohistochemical study.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(4):451-6.
2006: Lumbreras M; Baamonde C; Martínez-Cué C; Lubec G; Cairns N; Sallés J; Dierssen M; Flórez J
Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease.
Amino acids 2006;31(4):449-56.
2006: Armstrong R A; Cairns N J
Laminar degeneration of the frontal and temporal cortex in neuronal intermediate filament inclusion disease (NIFID): a study original using alpha-internexin immunohistochemistry.
Clinical neuropathology 2006;25(5):209-15.
2006: Mukherjee Odity; Pastor Pau; Cairns Nigel J; Chakraverty Sumi; Kauwe John S K; Shears Shantia; Behrens Maria I; Budde John; Hinrichs Anthony L; Norton Joanne; Levitch Denise; Taylor-Reinwald Lisa; Gitcho Michael; Tu P-H; Tenenholz Grinberg Lea; Liscic Rajka M; Armendariz Javier; Morris John C; Goate Alison M
HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin.
Annals of neurology 2006;60(3):314-22.
2006: Armstrong R A; Cairns N J; Lantos P L
Multiple system atrophy (MSA): topographic distribution of the alpha-synuclein-associated pathological changes.
Parkinsonism & related disorders 2006;12(6):356-62.
2006: Armstrong R A; Kerty E; Skullerud K; Cairns N J
Neuropathological changes in ten cases of neuronal intermediate filament inclusion disease (NIFID): a study using alpha-internexin immunohistochemistry and principal components analysis (PCA).
Journal of neural transmission (Vienna, Austria : 1996) 2006;113(9):1207-15.
2006: Armstrong R A; Cairns N J; Ironside J W
Size frequency distributions of the florid prion protein aggregates in variant Creutzfeldt-Jakob disease follow a power-law function.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2006;27(2):104-9.
2006: Forman Mark S; Mackenzie Ian R; Cairns Nigel J; Swanson Eric; Boyer Philip J; Drachman David A; Jhaveri Bharati S; Karlawish Jason H; Pestronk Alan; Smith Thomas W; Tu Pang-Hsien; Watts Giles D J; Markesbery William R; Smith Charles D; Kimonis Virginia E
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations.
Journal of neuropathology and experimental neurology 2006;65(6):571-81.
2006: Hashemzadeh-Bonehi Lida; Phillips Roger Guy; Cairns Nigel John; Mosaheb Sabrina; Thorpe Julian Robert
Pin1 protein associates with neuronal lipofuscin: potential consequences in age-related neurodegeneration.
Experimental neurology 2006;199(2):328-38.
2006: Armstrong R A; Cairns N J
Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2006;13(5):528-32.
2006: Momeni Parastoo; Cairns Nigel J; Perry Robert H; Bigio Eileen H; Gearing Marla; Singleton Andrew B; Hardy John
Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID).
Neurobiology of aging 2006;27(5):778.e1-778.e6.
2006: Cairns Nigel J; Bigio Eileen H; Mackenzie Ian Ra
Letter to the editor.
Journal of neuropathology and experimental neurology 2006;65(1):97; author reply 97-8.
2006: Momeni Parastoo; Schymick Jennifer; Jain Shushant; Cookson Mark R; Cairns Nigel J; Greggio Elisa; Greenway Matthew J; Berger Stephen; Pickering-Brown Stuart; Chiò Adriano; Fung Hon Chung; Holtzman David M; Huey Edward D; Wassermann Eric M; Adamson Jennifer; Hutton Michael L; Rogaeva Ekaterina; St George-Hyslop Peter; Rothstein Jeffrey D; Hardiman Orla; Grafman Jordan; Singleton Andrew; Hardy John; Traynor Bryan J
Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD.
BMC neurology 2006;6():44.
2005: Cairns Nigel J; Armstrong Richard A
Spatial patterns of the pathological changes in the temporal lobe of patients with neuronal intermediate filament inclusion disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2005;25(4):298-303.
2005: Armstrong R A; Cairns N J; Ironside J W; Lantos P L
Size frequency distribution of prion protein (PrP) aggregates in variant Creutzfeldt-Jakob disease (vCJD).
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(11):1565-73.
2005: Mosaheb Sabrina; Thorpe Julian R; Hashemzadeh-Bonehi Lida; Bigio Eileen H; Gearing Marla; Cairns Nigel J
Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease.
Acta neuropathologica 2005;110(4):360-8.
2005: Armstrong R A; Lantos P L; Cairns N J
Multiple system atrophy: laminar distribution of the pathological changes in frontal and temporal neocortex--a study in ten patients.
Clinical neuropathology 2005;24(5):230-5.
2005: Rezaie Payam; Pontikis Charlie C; Hudson Lance; Cairns Nigel J; Lantos Peter L
Expression of cellular prion protein in the frontal and occipital lobe in Alzheimer's disease, diffuse Lewy body disease, and in normal brain: an immunohistochemical study.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(8):929-40.
2005: Sudo Satoru; Shiozawa Masaki; Cairns Nigel J; Wada Yuji
Aberrant accentuation of neurofibrillary degeneration in the hippocampus of Alzheimer's disease with amyloid precursor protein 717 and presenilin-1 gene mutations.
Journal of the neurological sciences 2005;234(1-2):55-65.
2005: Armstrong Richard A; Lantos Peter L; Cairns Nigel J
Overlap between neurodegenerative disorders.
Neuropathology : official journal of the Japanese Society of Neuropathology 2005;25(2):111-24.
2005: Blomqvist Mia E-L; Chalmers Katy; Andreasen Niels; Bogdanovic Nenad; Wilcock Gordon K; Cairns Nigel J; Feuk Lars; Brookes Anthony J; Love Seth; Blennow Kaj; Kehoe Patrick G; Prince Jonathan A
Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.
Neurobiology of aging 2005;26(6):795-802.
2005: Cairns N J; Armstrong R A
Spatial correlations between the neuronal inclusions, swollen achromatic neurons, and glial cells in neuronal intermediate filament inclusion disease (NIFID).
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(4):473-80.
2005: Jamieson Sarra E; White Jacqueline K; Howson Joanna M M; Pask Rebecca; Smith Anne N; Brayne Carol; Evans John Grimley; Xuereb John; Cairns Nigel J; Rubinsztein David C; Blackwell Jenefer M
Candidate gene association study of solute carrier family 11a members 1 (SLC11A1) and 2 (SLC11A2) genes in Alzheimer's disease.
Neuroscience letters 2005;374(2):124-8.
2005: Cook Lynnette J; Ho Luk W; Wang Lin; Terrenoire Edith; Brayne Carol; Evans John Grimley; Xuereb John; Cairns Nigel J; Turic Dragana; Hollingworth Paul; Moore Pamela J; Jehu Luke; Archer Nicola; Walter Sarah; Foy Catherine; Edmondson Amanda; Powell John; Lovestone Simon; Williams Julie; Rubinsztein David C
Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):5-8.
2004: Cairns Nigel J; Lee Virginia M-Y; Trojanowski John Q
The cytoskeleton in neurodegenerative diseases.
The Journal of pathology 2004;204(4):438-49.
2004: Thorpe Julian R; Mosaheb Sabrina; Hashemzadeh-Bonehi Lida; Cairns Nigel J; Kay John E; Morley Simon J; Rulten Stuart L
Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias.
Neurobiology of disease 2004;17(2):237-49.
2004: Cairns N J; Grossman M; Arnold S E; Burn D J; Jaros E; Perry R H; Duyckaerts C; Stankoff B; Pillon B; Skullerud K; Cruz-Sanchez F F; Bigio E H; Mackenzie I R A; Gearing M; Juncos J L; Glass J D; Yokoo H; Nakazato Y; Mosaheb S; Thorpe J R; Uryu K; Lee V M-Y; Trojanowski J Q
Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease.
Neurology 2004;63(8):1376-84.
2004: Schuessel K; Leutner S; Cairns N J; Müller W E; Eckert A
Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(9):1167-82.
2004: Cairns Nigel J; Uryu Kunihiro; Bigio Eileen H; Mackenzie Ian R A; Gearing Marla; Duyckaerts Charles; Yokoo Hideaki; Nakazato Yoichi; Jaros Evelyn; Perry Robert H; Arnold Steven E; Lee Virginia M-Y; Trojanowski John Q
alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases.
Acta neuropathologica 2004;108(3):213-23.
2004: Cairns Nigel J; Zhukareva Victoria; Uryu Kunihiro; Zhang Bin; Bigio Eileen; Mackenzie Ian R A; Gearing Marla; Duyckaerts Charles; Yokoo Hideaki; Nakazato Yoichi; Jaros Evelyn; Perry Robert H; Lee Virginia M-Y; Trojanowski John Q
alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease.
The American journal of pathology 2004;164(6):2153-61.
2004: Cairns N J; Armstrong R A
Quantification of the pathological changes in the temporal lobe of patients with a novel neurofilamentopathy: neurofilament inclusion disease (NID).
Clinical neuropathology 2004;23(3):107-12.
2004: Armstrong R A; Cairns N J; Lantos P L
A quantitative study of the pathological changes in ten patients with multiple system atrophy (MSA).
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(4):485-95.
2004: Katzov Hagit; Chalmers Katy; Palmgren Juni; Andreasen Niels; Johansson Boo; Cairns Nigel J; Gatz Margaret; Wilcock Gordon K; Love Seth; Pedersen Nancy L; Brookes Anthony J; Blennow Kaj; Kehoe Patrick G; Prince Jonathan A
Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.
Human mutation 2004;23(4):358-67.
2004: Kehoe Patrick G; Katzov Hagit; Andreasen Niels; Gatz Maragaret; Wilcock Gordon K; Cairns Nigel J; Palmgren Juni; de Faire Ulf; Brookes Anthony J; Pedersen Nancy L; Blennow Kaj; Prince Jonathan A
Common variants of ACE contribute to variable age-at-onset of Alzheimer's disease.
Human genetics 2004;114(5):478-83.
2004: Cook Lynnette J; Ho Luk W; Taylor Alison E; Brayne Carol; Evans John Grimley; Xuereb John; Cairns Nigel J; Pritchard Antonia; Lemmon Helen; Mann David; St Clair David; Turic Dragana; Hollingworth Paul; Moore Pamela J; Jehu Luke; Archer Nicola; Walter Sarah; Foy Catherine; Edmondson Amanda; Powell John; Lovestone Simon; Owen Michael J; Williams Julie; Lendon Corinne; Rubinsztein David C
Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.
Neuroscience letters 2004;358(2):142-6.
2004: Preece Paul; Virley David J; Costandi Moheb; Coombes Robert; Moss Stephen J; Mudge Anne W; Jazin Elena; Cairns Nigel J
Amyloid precursor protein mRNA levels in Alzheimer's disease brain.
Brain research. Molecular brain research 2004;122(1):1-9.
2004: Armstrong Richard A; Lantos Peter L; Cairns Nigel J
Spatial patterns of alpha-synuclein positive glial cytoplasmic inclusions in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2004;19(1):109-12.
2004: Cairns N J; Jaros E; Perry R H; Armstrong R A
Temporal lobe pathology of human patients with neurofilament inclusion disease.
Neuroscience letters 2004;354(3):245-7.
2003: Armstrong R A; Lantos P L; Ironside J W; Cairns N J
Spatial correlation between the vacuolation, prion protein, deposition and surviving neurons in patients with Creutzfeldt-Jakob disease (vCJD).
Journal of neural transmission (Vienna, Austria : 1996) 2003;110(11):1303-11.
2003: Preece Paul; Cairns Nigel J
Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance.
Brain research. Molecular brain research 2003;118(1-2):60-71.
2003: Culpan Doris; MacGowan Sian H; Ford Julia M; Nicoll James A R; Griffin W Sue; Dewar Deborah; Cairns Nigel J; Hughes Anthony; Kehoe Patrick G; Wilcock Gordon K
Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.
Neuroscience letters 2003;350(1):61-5.
2003: Armstrong Richard A; Lantos Peter L; Cairns Nigel J
A quantitative study of the pathological changes in cortical neurons in sporadic Creutzfeldt-Jakob disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(3):181-7.
2003: Armstrong R A; Lantos P L; Ironside J W; Cairns N J
Differences in the density and spatial distribution of florid and diffuse plaques in variant Creutzfeldt-Jakob disease (vCJD).
Clinical neuropathology 2003;22(5):209-14.
2003: Armstrong R A; Cairns N J; Ironside J W; Lantos P L
Does the neuropathology of human patients with variant Creutzfeldt-Jakob disease reflect haematogenous spread of the disease?
Neuroscience letters 2003;348(1):37-40.
2003: Preece Paul; Virley David J; Costandi Moheb; Coombes Robert; Moss Stephen J; Mudge Anne W; Jazin Elena; Cairns Nigel J
Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease.
Brain research. Molecular brain research 2003;116(1-2):155-8.
2003: Preece Paul; Virley David J; Costandi Moheb; Coombes Robert; Moss Stephen J; Mudge Anne W; Jazin Elena; Cairns Nigel J
An optimistic view for quantifying mRNA in post-mortem human brain.
Brain research. Molecular brain research 2003;116(1-2):7-16.
2003: Kovács Tibor; Papp Mátyás I; Cairns Nigel J; Khan M Nadeem; Lantos Peter L
Olfactory bulb in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2003;18(8):938-42.
2003: Cairns N J; Armstrong R A
Clustering of neuronal inclusions in "dementia with neurofilament inclusions".
Acta neuropathologica 2003;106(2):125-8.
2003: Cairns N J; Brännström T; Khan M N; Rossor M N; Lantos P L
Neuronal loss in familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions.
Experimental neurology 2003;181(2):319-26.
2003: Cairns Nigel J; Perry Robert H; Jaros Evelyn; Burn David; McKeith Ian G; Lowe James S; Holton Janice; Rossor Martin N; Skullerud Kari; Duyckaerts Charles; Cruz-Sanchez Felix F; Lantos Peter L
Patients with a novel neurofilamentopathy: dementia with neurofilament inclusions.
Neuroscience letters 2003;341(3):177-80.
2003: Kehoe Patrick G; Katzov Hagit; Feuk Lars; Bennet Anna M; Johansson Boo; Wiman Björn; de Faire Ulf; Cairns Nigel J; Wilcock Gordon K; Brookes Anthony J; Blennow Kaj; Prince Jonathan A
Haplotypes extending across ACE are associated with Alzheimer's disease.
Human molecular genetics 2003;12(8):859-67.
2003: Shiozawa Masaki; Fukutani Yuken; Arai Nobutaka; Cairns Nigel J; Mizutani Toshio; Isaki Kiminori; Lantos Peter L; Wada Yuji
Glyceraldehyde 3-phosphate dehydrogenase and endothelin-1 immunoreactivity is associated with cerebral white matter damage in dentatorubral-pallidoluysian atrophy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(1):36-43.
2003: Krapfenbauer Kurt; Engidawork Ephrem; Cairns Nigel; Fountoulakis Michael; Lubec Gert
Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders.
Brain research 2003;967(1-2):152-60.
2003: Teufel Michael; Saudek Vladimir; Ledig Jean-Pierre; Bernhardt Annie; Boularand Sylviane; Carreau Alexandra; Cairns Nigel J; Carter Christopher; Cowley David J; Duverger Danielle; Ganzhorn Axel J; Guenet Chantal; Heintzelmann Blanche; Laucher Veronique; Sauvage Claude; Smirnova Tatiana
Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase.
The Journal of biological chemistry 2003;278(8):6521-31.
2003: Greber-Platzer Susanne; Fleischmann Christine; Nussbaumer Christa; Cairns Nigel; Lubec Gert
Increased RNA levels of the 25 kDa synaptosomal associated protein in brain samples of adult patients with Down Syndrome.
Neuroscience letters 2003;336(2):77-80.
2003: Pollak D; Cairns N; Lubec G
Cytoskeleton derangement in brain of patients with Down syndrome, Alzheimer's disease and Pick's disease.
Journal of neural transmission. Supplementum 2003;(67):149-58.
2003: Armstrong Richard A; Cairns Nigel J
Spatial patterns of the pathological changes in the cerebellar cortex in sporadic Creutzfeldt-Jakob disease (sCJD).
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2003;41(4):183-9.
2002: Yoo Byong Chul; Krapfenbauer Kurt; Cairns Nigel; Belay Girma; Bajo Michal; Lubec Gert
Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 2002;334(3):196-200.
2002: Armstrong R A; Cairns N J; Ironside J W; Lantos P L
The spatial patterns of prion protein deposits in cases of variant Creutzfeldt-Jakob disease.
Acta neuropathologica 2002;104(6):665-9.
2002: Armstrong R A; Lantos P L; Cairns N J
Spatial patterns of the vacuolation in subcortical white matter in sporadic Creutzfeldt-Jakob disease (sCJD).
Clinical neuropathology 2002;21(6):284-8.
2002: Cook Lynnette; Brayne Carol E; Easton Douglas; Evans John Grimley; Xuereb John; Cairns Nigel J; Rubinsztein David C
No evidence for an association between Saitohin Q7R polymorphism and Alzheimer's disease.
Annals of neurology 2002;52(5):690-1.
2002: Bond Brian C; Virley David J; Cairns Nigel J; Hunter A Jackie; Moore Gary B T; Moss Stephen J; Mudge Anne W; Walsh Frank S; Jazin Elena; Preece Paul
The quantification of gene expression in an animal model of brain ischaemia using TaqMan real-time RT-PCR.
Brain research. Molecular brain research 2002;106(1-2):101-16.
2002: Armstrong Richard A; Cairns Nigel J; Lantos Peter L
Are pathological lesions in neurodegenerative disorders the cause or the effect of the degeneration?
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(3):133-46.
2002: Valerio Alessandra; Ferrario Marina; Paterlini Marta; Liberini Paolo; Moretto Giuseppe; Cairns Nigel J; Pizzi Marina; Spano PierFranco
Spinal cord mGlu1a receptors: possible target for amyotrophic lateral sclerosis therapy.
Pharmacology, biochemistry, and behavior 2002;73(2):447-54.
2002: Kim Seong Hwan; Fountoulakis Michael; Cairns Nigel J; Lubec Gert
Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome.
Biochemical and biophysical research communications 2002;296(4):970-5.
2002: Emilsson Lina; Saetre Peter; Balciuniene Jorune; Castensson Anja; Cairns Nigel; Jazin Elena E
Increased monoamine oxidase messenger RNA expression levels in frontal cortex of Alzheimer's disease patients.
Neuroscience letters 2002;326(1):56-60.
2002: Ballard Clive; Johnson Mary; Piggott Margaret; Perry Robert; O'Brien John; Rowan Elise; Perry Elaine; Lantos Peter; Cairns Nigel; Holmes Clive
A positive association between 5HT re-uptake binding sites and depression in dementia with Lewy bodies.
Journal of affective disorders 2002;69(1-3):219-23.
2002: Armstrong R A; Cairns N J; Ironside J W; Lantos P L
Quantification of vacuolation ("spongiform change"), surviving neurones and prion protein deposition in eleven cases of variant Creutzfeldt-Jakob disease.
Neuropathology and applied neurobiology 2002;28(2):129-35.
2002: Lantos P L; Cairns N J; Khan M N; King A; Revesz T; Janssen J C; Morris H; Rossor M N
Neuropathologic variation in frontotemporal dementia due to the intronic tau 10(+16) mutation.
Neurology 2002;58(8):1169-75.
2002: Kim Seong Hwan; Krapfenbauer Kurt; Cheon Myeong Sook; Fountoulakis Michael; Cairns Nigel J; Lubec Gert
Human brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and increased in Pick's disease.
Neuroscience letters 2002;321(3):169-72.
2002: Armstrong Richard A; Cairns Nigel J; Ironside James W; Lantos Peter L
Laminar distribution of the pathological changes in the cerebral cortex in variant Creutzfeldt-Jakob disease (vCJD).
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2002;40(4):165-71.
2001: Armstrong R A; Lantos P L; Cairns N J
Spatial correlations between the vacuolation, prion protein deposits, and surviving neurons in the cerebral cortex in sporadic Creutzfeldt-Jakob disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(4):266-71.
2001: Taylor A; Ezquerra M; Bagri G; Yip A; Goumidi L; Cottel D; Easton D; Evans J G; Xuereb J; Cairns N J; Amouyel P; Chartier-Harlin M C; Brayne C; Rubinsztein D C
Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes.
American journal of medical genetics 2001;105(8):761-4.
2001: Court J A; Ballard C G; Piggott M A; Johnson M; O'Brien J T; Holmes C; Cairns N; Lantos P; Perry R H; Jaros E; Perry E K
Visual hallucinations are associated with lower alpha bungarotoxin binding in dementia with Lewy bodies.
Pharmacology, biochemistry, and behavior 2001;70(4):571-9.
2001: Armstrong R A; Cairns N J; Lantos P L
Quantification of the vacuolation (spongiform change) and prion protein deposition in 11 patients with sporadic Creutzfeldt-Jakob disease.
Acta neuropathologica 2001;102(6):591-6.
2001: Lambri M; Djurovic V; Kibble M; Cairns N; Al-Sarraj S
Specificity and sensitivity of betaAPP in head injury.
Clinical neuropathology 2001;20(6):263-71.
2001: Vlkolinský R; Cairns N; Fountoulakis M; Lubec G
Decreased brain levels of 2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's disease.
Neurobiology of aging 2001;22(4):547-53.
2001: Mann D M; Takeuchi A; Sato S; Cairns N J; Lantos P L; Rossor M N; Haltia M; Kalimo H; Iwatsubo T
Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques.
Neuropathology and applied neurobiology 2001;27(3):189-96.
2001: Schuller E; Gulesserian T; Seidl R; Cairns N; Lube G
Brain t-complex polypeptide 1 (TCP- 1) related to its natural substrate beta1 tubulin is decreased in Alzheimer's disease.
Life sciences 2001;69(3):263-70.
2001: Seidl R; Bidmon B; Bajo M; Yoo P C; Cairns N; LaCasse E C; Lubec G
Evidence for apoptosis in the fetal Down syndrome brain.
Journal of child neurology 2001;16(6):438-42.
2001: Kim S H; Vlkolinsky R; Cairns N; Fountoulakis M; Lubec G
The reduction of NADH ubiquinone oxidoreductase 24- and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease.
Life sciences 2001;68(24):2741-50.
2001: Ishii K; Lippa C; Tomiyama T; Miyatake F; Ozawa K; Tamaoka A; Hasegawa T; Fraser P E; Shoji S; Nee L E; Pollen D A; St George-Hyslop P H; Ii K; Ohtake T; Kalaria R N; Rossor M N; Lantos P L; Cairns N J; Farrer L A; Mori H
Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition.
Neurobiology of aging 2001;22(3):367-76.
2001: Engidawork E; Gulesserian T; Seidl R; Cairns N; Lubec G
Expression of apoptosis related proteins in brains of patients with Alzheimer's disease.
Neuroscience letters 2001;303(2):79-82.
2001: Yoo B C; Cairns N; Fountoulakis M; Lubec G
Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and Alzheimer's disease.
Dementia and geriatric cognitive disorders 2001;12(3):219-25.
2001: Yoo B C; Vlkolinsky R; Engidawork E; Cairns N; Fountoulakis M; Lubec G
Differential expression of molecular chaperones in brain of patients with Down syndrome.
Electrophoresis 2001;22(6):1233-41.
2001: Taylor A E; Yip A; Brayne C; Easton D; Evans J G; Xuereb J; Cairns N; Esiri M M; Rubinsztein D C
Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease.
Journal of medical genetics 2001;38(4):232-3.
2001: Krapfenbauer K; Yoo B C; Kim S H; Cairns N; Lubec G
Differential display reveals downregulation of the phospholipid transfer protein (PLTP) at the mRNA level in brains of patients with Down syndrome.
Life sciences 2001;68(18):2169-79.
2001: Armstrong R A; Cairns N J; Lantos P L
Spatial pattern of prion protein deposits in patients with sporadic Creutzfeldt-Jakob disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(1):19-24.
2001: Armstrong R A; Cairns N J; Lantos P L
What does the study of the spatial patterns of pathological lesions tell us about the pathogenesis of neurodegenerative disorders?
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(1):1-12.
2001: Murphy T; Yip A; Brayne C; Easton D; Evans J G; Xuereb J; Cairns N; Esiri M M; Rubinsztein D C
The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease.
Neuroreport 2001;12(3):631-4.
2001: Kim S H; Cairns N; Fountoulakisc M; Lubec G
Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease.
Neuroscience letters 2001;300(1):41-4.
2001: Cheon M S; Bajo M; Gulesserian T; Cairns N; Lubec G
Evidence for the relation of herpes simplex virus type 1 to Down syndrome and Alzheimer's disease.
Electrophoresis 2001;22(3):445-8.
2001: Seidl R; Cairns N; Singewald N; Kaehler S T; Lubec G
Differences between GABA levels in Alzheimer's disease and Down syndrome with Alzheimer-like neuropathology.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(2):139-45.
2001: Kovács T; Cairns N J; Lantos P L
Olfactory centres in Alzheimer's disease: olfactory bulb is involved in early Braak's stages.
Neuroreport 2001;12(2):285-8.
2001: Engidawork E; Gulesserian T; Yoo B C; Cairns N; Lubec G
Alteration of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease.
Biochemical and biophysical research communications 2001;281(1):84-93.
2001: Gulesserian T; Seidl R; Hardmeier R; Cairns N; Lubec G
Superoxide dismutase SOD1, encoded on chromosome 21, but not SOD2 is overexpressed in brains of patients with Down syndrome.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(1):41-6.
2001: Seidl R; Labudova O; Krapfenbauer K; Henriksson E W; Craft J; Turhani-Schatzmann D; Achsel T; Bidmon B; Pruijn G J; Cairns N; Lubec G
Deficient brain snRNP70K in patients with Down syndrome.
Electrophoresis 2001;22(1):43-8.
2001: Yoo B C; Fountoulakis M; Cairns N; Lubec G
Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome.
Electrophoresis 2001;22(1):172-9.
2001: Yoo B C; Kim S H; Cairns N; Fountoulakis M; Lubec G
Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease.
Biochemical and biophysical research communications 2001;280(1):249-58.
2001: Armstrong R A; Lantos P L; Cairns N J
The spatial patterns of prion protein deposits in Creutzfeldt-Jakob disease: comparison with beta-amyloid deposits in Alzheimer's disease.
Neuroscience letters 2001;298(1):53-6.
2001: Cairns N J
Molecular neuropathology of transgenic mouse models of Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):289-301.
2001: Cheon M S; Fountoulakis M; Cairns N J; Dierssen M; Herkner K; Lubec G
Decreased protein levels of stathmin in adult brains with Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):281-8.
2001: Kim S H; Nairn A C; Cairns N; Lubec G
Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):263-72.
2001: Seidl R; Cairns N; Lubec G
The brain in Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):247-61.
2001: Kim S H; Fountoulakis M; Cairns N; Lubec G
Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):223-35.
2001: Engidawork E; Gulesserian T; Balic N; Cairns N; Lubec G
Changes in nicotinic acetylcholine receptor subunits expression in brain of patients with Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):211-22.
2001: Balcz B; Kirchner L; Cairns N; Fountoulakis M; Lubec G
Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):193-201.
2001: Engidawork E; Gulesserian T; Seidl R; Cairns N; Lubec G
Expression of apoptosis related proteins: RAIDD, ZIP kinase, Bim/BOD, p21, Bax, Bcl-2 and NF-kappaB in brains of patients with Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):181-92.
2001: Gulesserian T; Engidawork E; Yoo B C; Cairns N; Lubec G
Alteration of caspases and other apoptosis regulatory proteins in Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):163-79.
2001: Bajo M; Yoo B C; Cairns N; Gratzer M; Lubec G
Neurofilament proteins NF-L, NF-M and NF-H in brain of patients with Down syndrome and Alzheimer's disease.
Amino acids 2001;21(3):293-301.
2000: Bell K; Cairns N J; Lantos P L; Rossor M N
Immunohistochemistry distinguishes: between Pick's disease and corticobasal degeneration.
Journal of neurology, neurosurgery, and psychiatry 2000;69(6):835-6.
2000: Morris H R; Vaughan J R; Datta S R; Bandopadhyay R; Rohan De Silva H A; Schrag A; Cairns N J; Burn D; Nath U; Lantos P L; Daniel S; Lees A J; Quinn N P; Wood N W
Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE.
Neurology 2000;55(12):1918-20.
2000: Ballard C; Piggott M; Johnson M; Cairns N; Perry R; McKeith I; Jaros E; O'Brien J; Holmes C; Perry E
Delusions associated with elevated muscarinic binding in dementia with Lewy bodies.
Annals of neurology 2000;48(6):868-76.
2000: Pickering-Brown S; Baker M; Yen S H; Liu W K; Hasegawa M; Cairns N; Lantos P L; Rossor M; Iwatsubo T; Davies Y; Allsop D; Furlong R; Owen F; Hardy J; Mann D; Hutton M
Pick's disease is associated with mutations in the tau gene.
Annals of neurology 2000;48(6):859-67.
2000: Gulesserian T; Engidawork E; Cairns N; Lubec G
Increased protein levels of serotonin transporter in frontal cortex of patients with Down syndrome.
Neuroscience letters 2000;296(1):53-7.
2000: Kim S H; Vlkolinsky R; Cairns N; Lubec G
Decreased levels of complex III core protein 1 and complex V beta chain in brains from patients with Alzheimer's disease and Down syndrome.
Cellular and molecular life sciences : CMLS 2000;57(12):1810-6.
2000: Fukutani Y; Cairns N J; Shiozawa M; Sasaki K; Sudo S; Isaki K; Lantos P L
Neuronal loss and neurofibrillary degeneration in the hippocampal cortex in late-onset sporadic Alzheimer's disease.
Psychiatry and clinical neurosciences 2000;54(5):523-9.
2000: Armstrong R A; Cairns N J; Lantos P L
Clustering of Pick bodies in the dentate gyrus in Pick's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20(3):170-5.
2000: Kim S H; Yoo B C; Broers J L; Cairns N; Lubec G
Neuroendocrine-specific protein C, a marker of neuronal differentiation, is reduced in brain of patients with Down syndrome and Alzheimer's disease.
Biochemical and biophysical research communications 2000;276(1):329-34.
2000: Narain Y; Yip A; Murphy T; Brayne C; Easton D; Evans J G; Xuereb J; Cairns N; Esiri M M; Furlong R A; Rubinsztein D C
The ACE gene and Alzheimer's disease susceptibility.
Journal of medical genetics 2000;37(9):695-7.
2000: Shiozawa M; Fukutani Y; Sasaki K; Isaki K; Hamano T; Hirayama M; Imamura K; Mukai M; Arai N; Cairns N J
Corticobasal degeneration: an autopsy case clinically diagnosed as progressive supranuclear palsy.
Clinical neuropathology 2000;19(4):192-9.
2000: Armstrong R A; Cairns N J; Lantos P L
Beta-amyloid deposition in the temporal lobe of patients with dementia with Lewy bodies: comparison with non-demented cases and Alzheimer's disease.
Dementia and geriatric cognitive disorders 2000;11(4):187-92.
2000: Eckert G P; Cairns N J; Maras A; Gattaz W F; Müller W E
Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease.
Dementia and geriatric cognitive disorders 2000;11(4):181-6.
2000: Pickering-Brown S M; Owen F; Isaacs A; Snowden J; Varma A; Neary D; Furlong R; Daniel S E; Cairns N J; Mann D M
Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pick- or microvacuolar-type histology.
Experimental neurology 2000;163(2):452-6.
2000: Armstrong R A; Cairns N J; Lantos P L
A quantitative study of the pathological lesions in the neocortex and hippocampus of twelve patients with corticobasal degeneration.
Experimental neurology 2000;163(2):348-56.
2000: Eastwood S L; Cairns N J; Harrison P J
Synaptophysin gene expression in schizophrenia. Investigation of synaptic pathology in the cerebral cortex.
The British journal of psychiatry : the journal of mental science 2000;176():236-42.
2000: Armstrong R A; Cairns N J; Lantos P L
The spatial pattern of the vacuolation in patients with sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 2000;281(2-3):187-90.
1999: Kovács T; Cairns N J; Lantos P L
beta-amyloid deposition and neurofibrillary tangle formation in the olfactory bulb in ageing and Alzheimer's disease.
Neuropathology and applied neurobiology 1999;25(6):481-91.
1999: Karlsson K; Cairns N; Lubec G; Fountoulakis M
Enrichment of human brain proteins by heparin chromatography.
Electrophoresis 1999;20(14):2970-6.
1999: Court J; Spurden D; Lloyd S; McKeith I; Ballard C; Cairns N; Kerwin R; Perry R; Perry E
Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus.
Journal of neurochemistry 1999;73(4):1590-7.
1999: Kovács T; Cairns N J; Lantos P L
Alpha-2-macroglobulin intronic polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease.
Neuroscience letters 1999;273(1):61-83.
1999: Gómez-Isla T; Growdon W B; McNamara M J; Nochlin D; Bird T D; Arango J C; Lopera F; Kosik K S; Lantos P L; Cairns N J; Hyman B T
The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors.
Brain : a journal of neurology 1999;122 ( Pt 9)():1709-19.
1999: Armstrong R A; Cairns N J; Lantos P L
Laminar distribution of pick bodies, pick cells and Alzheimer disease pathology in the frontal and temporal cortex in Pick's disease.
Neuropathology and applied neurobiology 1999;25(4):266-71.
1999: Guan Z; Wang Y; Cairns N J; Lantos P L; Dallner G; Sindelar P J
Decrease and structural modifications of phosphatidylethanolamine plasmalogen in the brain with Alzheimer disease.
Journal of neuropathology and experimental neurology 1999;58(7):740-7.
1999: Ballard C; Holmes C; McKeith I; Neill D; O'Brien J; Cairns N; Lantos P; Perry E; Ince P; Perry R
Psychiatric morbidity in dementia with Lewy bodies: a prospective clinical and neuropathological comparative study with Alzheimer's disease.
The American journal of psychiatry 1999;156(7):1039-45.
1999: Armstrong R A; Cairns N J; Lantos P L
Clustering of cerebral cortical lesions in patients with corticobasal degeneration.
Neuroscience letters 1999;268(1):5-8.
1999: Armstrong R A; Cairns N J; Lantos P L
Quantification of pathological lesions in the frontal and temporal lobe of ten patients diagnosed with Pick's disease.
Acta neuropathologica 1999;97(5):456-62.
1999: Dow D J; Lindsey N; Cairns N J; Brayne C; Robinson D; Huppert F A; Paykel E S; Xuereb J; Wilcock G; Whittaker J L; Rubinsztein D C
Alpha-2 macroglobulin polymorphism and Alzheimer disease risk in the UK.
Nature genetics 1999;22(1):16-7; author reply 21-2.
1999: Greber S; Lubec G; Cairns N; Fountoulakis M
Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down syndrome and Alzheimer's disease.
Electrophoresis 1999;20(4-5):928-34.
1999: Langen H; Berndt P; Röder D; Cairns N; Lubec G; Fountoulakis M
Two-dimensional map of human brain proteins.
Electrophoresis 1999;20(4-5):907-16.
1999: Labudova O; Kitzmueller E; Rink H; Cairns N; Lubec G
Increased phosphoglycerate kinase in the brains of patients with Down's syndrome but not with Alzheimer's disease.
Clinical science (London, England : 1979) 1999;96(3):279-85.
1999: Fukutani Y; Cairns N J; Everall I P; Chadwick A; Isaki K; Lantos P L
Cerebellar dentate nucleus in Alzheimer's disease with myoclonus.
Dementia and geriatric cognitive disorders 1999;10(2):81-8.
1999: Armstrong R; Cairns N; Lantos P
The spatial patterns of Pick bodies, Pick cells and Alzheimer's disease pathology in Pick's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 1999;19(1):64-70.
1999: Holmes C; Cairns N; Lantos P; Mann A
Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies.
The British journal of psychiatry : the journal of mental science 1999;174():45-50.
1999: Seidl R; Fang-Kircher S; Bidmon B; Cairns N; Lubec G
Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome.
Neuroscience letters 1999;260(1):9-12.
1999: Lubec G; Labudova O; Cairns N; Fountoulakis M
Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down's syndrome.
Neuroscience letters 1999;260(2):141-5.
1999: Kehoe P G; Russ C; McIlory S; Williams H; Holmans P; Holmes C; Liolitsa D; Vahidassr D; Powell J; McGleenon B; Liddell M; Plomin R; Dynan K; Williams N; Neal J; Cairns N J; Wilcock G; Passmore P; Lovestone S; Williams J; Owen M J
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
Nature genetics 1999;21(1):71-2.
1999: Eckert G P; Cairns N J; Müller W E
Piracetam reverses hippocampal membrane alterations in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1999;106(7-8):757-61.
1999: Schatzmann-Turhani D; Labudova O; Yeghiazaryan K; Rink H; Hauser E; Cairns N; Lubec G
Overexpression of DNAse I in brain of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():353-62.
1999: Fountoulakis M; Cairns N; Lubec G
Increased levels of 14-3-3 gamma and epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome.
Journal of neural transmission. Supplementum 1999;57():323-35.
1999: Yoo B C; Seidl R; Cairns N; Lubec G
Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 1999;57():315-22.
1999: Yeghiazaryan K; Turhani-Schatzmann D; Labudova O; Schuller E; Olson E N; Cairns N; Lubec G
Downregulation of the transcription factor scleraxis in brain of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():305-14.
1999: Seidl R; Bajo M; Böhm K; LaCasse E C; MacKenzie A E; Cairns N; Lubec G
Neuronal apoptosis inhibitory protein (NAIP)-like immunoreactivity in brains of adult patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():283-91.
1999: Greber-Platzer S; Schatzmann-Turhani D; Cairns N; Balcz B; Lubec G
Expression of the transcription factor ETS2 in brain of patients with Down syndrome--evidence against the overexpression-gene dosage hypothesis.
Journal of neural transmission. Supplementum 1999;57():269-81.
1999: Labudova O; Cairns N; Kitzmüller E; Lubec G
Impaired brain glucose metabolism in patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():247-56.
1999: Seidl R; Kaehler S T; Prast H; Singewald N; Cairns N; Gratzer M; Lubec G
Serotonin (5-HT) in brains of adult patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():221-32.
1999: Krapfenbauer K; Yoo B C; Cairns N; Lubec G
Differential display reveals deteriorated mRNA levels of NADH3 (complex I) in cerebellum of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():211-20.
1999: Lubec G; Nonaka M; Krapfenbauer K; Gratzer M; Cairns N; Fountoulakis M
Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level.
Journal of neural transmission. Supplementum 1999;57():161-77.
1999: Labudova O; Kitzmueller E; Rink H; Cairns N; Lubec G
Gene expression in fetal Down syndrome brain as revealed by subtractive hybridization.
Journal of neural transmission. Supplementum 1999;57():125-36.
1999: Kitzmueller E; Labudova O; Rink H; Cairns N; Lubec G
Altered gene expression in fetal Down syndrome brain as revealed by the gene hunting technique of subtractive hybridization.
Journal of neural transmission. Supplementum 1999;57():99-124.
1999: Greber-Platzer S; Balcz B; Cairns N; Lubec G
c-fos expression in brains of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():75-85.
1999: Cairns N J
Neuropathology.
Journal of neural transmission. Supplementum 1999;57():61-74.
1999: Lubec G; Labudova O; Cairns N; Berndt P; Langen H; Fountoulakis M
Reduced aldehyde dehydrogenase levels in the brain of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():21-40.
1999: Fang-Kircher S G; Labudova O; Kitzmueller E; Rink H; Cairns N; Lubec G
Increased steady state mRNA levels of DNA-repair genes XRCC1, ERCC2 and ERCC3 in brain of patients with Down syndrome.
Life sciences 1999;64(18):1689-99.
1999: Labudova O; Cairns N; Koeck T; Kitzmueller E; Rink H; Lubec G
Thyroid stimulating hormone-receptor overexpression in brain of patients with Down syndrome and Alzheimer's disease.
Life sciences 1999;64(12):1037-44.
1999: Schatzmann-Turhani D; Greber-Platzer S; Cairns N; Lubec G
Determination of the protooncogene ets-2 gene transcript in human brain at the atto-gram-level by the use of competitive RT/PCR.
Amino acids 1999;16(1):13-9.
1998: Armstrong R A; Cairns N J; Lantos P L
Spatial distribution of diffuse, primitive, and classic amyloid-beta deposits and blood vessels in the upper laminae of the frontal cortex in Alzheimer disease.
Alzheimer disease and associated disorders 1998;12(4):378-83.
1998: Kehoe P G; Williams H; Holmans P; Wilcock G; Cairns N J; Neal J; Owen M J
The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.
Journal of medical genetics 1998;35(12):1034-5.
1998: Lippa C F; Fujiwara H; Mann D M; Giasson B; Baba M; Schmidt M L; Nee L E; O'Connell B; Pollen D A; St George-Hyslop P; Ghetti B; Nochlin D; Bird T D; Cairns N J; Lee V M; Iwatsubo T; Trojanowski J Q
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes.
The American journal of pathology 1998;153(5):1365-70.
1998: Labudova O; Fang-Kircher S; Cairns N; Moenkemann H; Yeghiazaryan K; Lubec G
Brain vasopressin levels in Down syndrome and Alzheimer's disease.
Brain research 1998;806(1):55-9.
1998: Labudova O; Krapfenbauer K; Moenkemann H; Rink H; Kitzmüller E; Cairns N; Lubec G
Decreased transcription factor junD in brains of patients with Down syndrome.
Neuroscience letters 1998;252(3):159-62.
1998: Spillantini M G; Crowther R A; Jakes R; Cairns N J; Lantos P L; Goedert M
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
Neuroscience letters 1998;251(3):205-8.
1998: Hermon M; Cairns N; Egly J M; Fery A; Labudova O; Lubec G
Expression of DNA excision-repair-cross-complementing proteins p80 and p89 in brain of patients with Down Syndrome and Alzheimer's disease.
Neuroscience letters 1998;251(1):45-8.
1998: Müller W E; Eckert G P; Scheuer K; Cairns N J; Maras A; Gattaz W F
Effects of beta-amyloid peptides on the fluidity of membranes from frontal and parietal lobes of human brain. High potencies of A beta 1-42 and A beta 1-43.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(1):10-5.
1998: Armstrong R A; Cairns N J; Lantos P L
The spatial patterns of Lewy bodies, senile plaques, and neurofibrillary tangles in dementia with Lewy bodies.
Experimental neurology 1998;150(1):122-7.
1998: Armstrong R A; Cairns N J; Lantos P L
Clustering of Pick bodies in patients with Pick's disease.
Neuroscience letters 1998;242(2):81-4.
1998: Tysoe C; Whittaker J; Xuereb J; Cairns N J; Cruts M; Van Broeckhoven C; Wilcock G; Rubinsztein D C
A presenilin-1 truncating mutation is present in two cases with autopsy-confirmed early-onset Alzheimer disease.
American journal of human genetics 1998;62(1):70-6.
1997: Rezaie P; Cairns N J; Male D K
Expression of adhesion molecules on human fetal cerebral vessels: relationship to microglial colonisation during development.
Brain research. Developmental brain research 1997;104(1-2):175-89.
1997: Marshall K A; Daniel S E; Cairns N; Jenner P; Halliwell B
Upregulation of the anti-apoptotic protein Bcl-2 may be an early event in neurodegeneration: studies on Parkinson's and incidental Lewy body disease.
Biochemical and biophysical research communications 1997;240(1):84-7.
1997: Seidl R; Greber S; Schuller E; Bernert G; Cairns N; Lubec G
Evidence against increased oxidative DNA-damage in Down syndrome.
Neuroscience letters 1997;235(3):137-40.
1997: Jones A L; Middle F; Guy C; Spurlock G; Cairns N J; McGuffin P; Craddock N; Owen M; O'Donovan M C
No evidence for expanded polyglutamine sequences in bipolar disorder and schizophrenia.
Molecular psychiatry 1997;2(6):478-82.
1997: Alam Z I; Jenner A; Daniel S E; Lees A J; Cairns N; Marsden C D; Jenner P; Halliwell B
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.
Journal of neurochemistry 1997;69(3):1196-203.
1997: Sawa A; Oyama F; Cairns N J; Amano N; Matsushita M
Aberrant expression of bcl-2 gene family in Down's syndrome brains.
Brain research. Molecular brain research 1997;48(1):53-9.
1997: Fukutani Y; Sasaki K; Mukai M; Matsubara R; Isaki K; Cairns N J
Neurons and extracellular neurofibrillary tangles in the hippocampal subdivisions in early-onset familial Alzheimer's disease: a case study.
Psychiatry and clinical neurosciences 1997;51(4):227-31.
1997: Seidl R; Schuller E; Cairns N; Lubec G
Evidence against increased glycoxidation in patients with Alzheimer's disease.
Neuroscience letters 1997;232(1):49-52.
1997: Fukutani Y; Cairns N J; Rossor M N; Lantos P L
Cerebellar pathology in sporadic and familial Alzheimer's disease including APP 717 (Val-->Ile) mutation cases: a morphometric investigation.
Journal of the neurological sciences 1997;149(2):177-84.
1997: Duberley R M; Johnson I P; Anand P; Leigh P N; Cairns N J
Immunocytochemical studies of neurotrophins in cerebral motor cortex in Amyotrophic Lateral Sclerosis.
Brain research 1997;763(2):259-63.
1997: Cairns N J; Atkinson P F; Hanger D P; Anderton B H; Daniel S E; Lantos P L
Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease.
Neuroscience letters 1997;230(1):49-52.
1997: Armstrong R A; Cairns N J; Lantos P L
beta-Amyloid (A beta) deposition in the medial temporal lobe of patients with dementia with Lewy bodies.
Neuroscience letters 1997;227(3):193-6.
1997: Duberley R M; Johnson I P; Anand P; Leigh P N; Cairns N J
Neurotrophin-3-like immunoreactivity and Trk C expression in human spinal motoneurones in amyotrophic lateral sclerosis.
Journal of the neurological sciences 1997;148(1):33-40.
1997: Lyras L; Cairns N J; Jenner A; Jenner P; Halliwell B
An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease.
Journal of neurochemistry 1997;68(5):2061-9.
1997: Armstrong R A; Cairns N J; Lantos P L
Dementia with Lewy bodies: clustering of Lewy bodies in human patients.
Neuroscience letters 1997;224(1):41-4.
1997: Schneider C; Risser D; Kirchner L; Kitzmüller E; Cairns N; Prast H; Singewald N; Lubec G
Similar deficits of central histaminergic system in patients with Down syndrome and Alzheimer disease.
Neuroscience letters 1997;222(3):183-6.
1997: Tysoe C; Whittaker J; Cairns N J; Atkinson P F; Harrington C R; Xuereb J; Wilcock G; Rubinsztein D C
Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease.
Neuroscience letters 1997;222(1):68-9.
1997: Cairns N J; Atkinson P F; Kovács T; Lees A J; Daniel S E; Lantos P L
Apolipoprotein E e4 allele frequency in patients with multiple system atrophy.
Neuroscience letters 1997;221(2-3):161-4.
1997: Risser D; Lubec G; Cairns N; Herrera-Marschitz M
Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome.
Life sciences 1997;60(15):1231-7.
1996: Cairns N J; Lantos P L
Brain tissue banks in psychiatric and neurological research.
Journal of clinical pathology 1996;49(11):870-3.
1996: Bernert G; Nemethova M; Herrera-Marschitz M; Cairns N; Lubec G
Decreased cyclin dependent kinase in brain of patients with Down syndrome.
Neuroscience letters 1996;216(1):68-70.
1996: Fukutani Y; Cairns N J; Rossor M N; Lantos P L
Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease.
Neuroscience letters 1996;214(1):33-6.
1996: Mann D M; Iwatsubo T; Cairns N J; Lantos P L; Nochlin D; Sumi S M; Bird T D; Poorkaj P; Hardy J; Hutton M; Prihar G; Crook R; Rossor M N; Haltia M
Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43).
Annals of neurology 1996;40(2):149-56.
1996: Scheuer K; Maras A; Gattaz W F; Cairns N; Förstl H; Müller W E
Cortical NMDA receptor properties and membrane fluidity are altered in Alzheimer's disease.
Dementia (Basel, Switzerland) 1996;7(4):210-4.
1996: Rezaie P; Cairns N J; Chadwick A; Lantos P L
Lewy bodies are located preferentially in limbic areas in diffuse Lewy body disease.
Neuroscience letters 1996;212(2):111-4.
1996: Muir P; Nicholson F; Spencer G T; Ajetunmobi J F; Starkey W G; Khan M; Archard L C; Cairns N J; Anderson V E; Leigh P N; Howard R S; Banatvala J E
Enterovirus infection of the central nervous system of humans: lack of association with chronic neurological disease.
The Journal of general virology 1996;77 ( Pt 7)():1469-76.
1996: Armstrong R A; Cairns N J; Patel R; Lantos P L; Rossor M N
Relationships between beta-amyloid (A beta) deposits and blood vessels in patients with sporadic and familial Alzheimer's disease.
Neuroscience letters 1996;207(3):171-4.
1996: Mann D M; Iwatsubo T; Ihara Y; Cairns N J; Lantos P L; Bogdanovic N; Lannfelt L; Winblad B; Maat-Schieman M L; Rossor M N
Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene.
The American journal of pathology 1996;148(4):1257-66.
1996: Anwar R; Moynihan T P; Ardley H; Brindle N; Coletta P L; Cairns N; Markham A F; Robinson P A
Molecular analysis of the presenilin 1 (S182) gene in "sporadic" cases of Alzheimer's disease: identification and characterisation of unusual splice variants.
Journal of neurochemistry 1996;66(4):1774-7.
1996: Armstrong R A; Cairns N J; Myers D; Smith C U; Lantos P L; Rossor M N
A comparison of beta-amyloid deposition in the medial temporal lobe in sporadic Alzheimer's disease, Down's syndrome and normal elderly brains.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1996;5(1):35-41.
1996: Seidl R; Beninati S; Cairns N; Singewald N; Risser D; Bavan H; Nemethova M; Lubec G
Polyamines in frontal cortex of patients with Down syndrome and Alzheimer disease.
Neuroscience letters 1996;206(2-3):193-5.
1996: Gattaz W F; Levy R; Cairns N J; Förstl H; Braus D F; Maras A
[Relevance of metabolism of membrane phospholipids for Alzheimer dementia]
Fortschritte der Neurologie-Psychiatrie 1996;64(1):8-12.
1996: Risser D; You Z B; Cairns N; Herrera-Marschitz M; Seidl R; Schneider C; Terenius L; Lubec G
Endogenous opioids in frontal cortex of patients with Down syndrome.
Neuroscience letters 1996;203(2):111-4.
1996: Hayn M; Kremser K; Singewald N; Cairns N; Nemethova M; Lubec B; Lubec G
Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in Down's syndrome and Alzheimer's disease.
Life sciences 1996;59(7):537-44.
1996: Gattaz W F; Cairns N J; Levy R; Förstl H; Braus D F; Maras A
Decreased phospholipase A2 activity in the brain and in platelets of patients with Alzheimer's disease.
European archives of psychiatry and clinical neuroscience 1996;246(3):129-31.
1996: Baran H; Cairns N; Lubec B; Lubec G
Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome.
Life sciences 1996;58(21):1891-9.
1995: Fukutani Y; Kobayashi K; Nakamura I; Watanabe K; Isaki K; Cairns N J
Neurons, intracellular and extracellular neurofibrillary tangles in subdivisions of the hippocampal cortex in normal ageing and Alzheimer's disease.
Neuroscience letters 1995;200(1):57-60.
1995: Muir P; Nicholson F; Sharief M K; Thompson E J; Cairns N J; Lantos P; Spencer G T; Kaminski H J; Banatvala J E
Evidence for persistent enterovirus infection of the central nervous system in patients with previous paralytic poliomyelitis.
Annals of the New York Academy of Sciences 1995;753():219-32.
1995: Anderson V E; Cairns N J; Leigh P N
Involvement of the amygdala, dentate and hippocampus in motor neuron disease.
Journal of the neurological sciences 1995;129 Suppl():75-8.
1995: Kingsbury A E; Foster O J; Nisbet A P; Cairns N; Bray L; Eve D J; Lees A J; Marsden C D
Tissue pH as an indicator of mRNA preservation in human post-mortem brain.
Brain research. Molecular brain research 1995;28(2):311-8.
1995: Gattaz W F; Maras A; Cairns N J; Levy R; Förstl H
Decreased phospholipase A2 activity in Alzheimer brains.
Biological psychiatry 1995;37(1):13-7.
1994: Förstl H; Burns A; Levy R; Cairns N
Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1994;165(2):53-9.
1994: Oyama F; Cairns N J; Shimada H; Oyama R; Titani K; Ihara Y
Down's syndrome: up-regulation of beta-amyloid protein precursor and tau mRNAs and their defective coordination.
Journal of neurochemistry 1994;62(3):1062-6.
1994: Förstl H; Levy R; Burns A; Luthert P; Cairns N
Disproportionate loss of noradrenergic and cholinergic neurons as cause of depression in Alzheimer's disease--a hypothesis.
Pharmacopsychiatry 1994;27(1):11-5.
1993: Förstl H; Burns A; Levy R; Cairns N; Luthert P; Lantos P
Neuropathological correlates of behavioural disturbance in confirmed Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1993;163():364-8.
1993: Förstl H; Burns A; Levy R; Cairns N
Neuropathological basis for drawing disability (constructional apraxia) in Alzheimer's disease.
Psychological medicine 1993;23(3):623-9.
1993: Förstl H; Burns A; Luthert P; Cairns N; Levy R
The Lewy-body variant of Alzheimer's disease. Clinical and pathological findings.
The British journal of psychiatry : the journal of mental science 1993;162():385-92.
1993: Ghauri F Y; Nicholson J K; Sweatman B C; Wood J; Beddell C R; Lindon J C; Cairns N J
NMR spectroscopy of human post mortem cerebrospinal fluid: distinction of Alzheimer's disease from control using pattern recognition and statistics.
NMR in biomedicine 1993;6(2):163-7.
1993: Cairns N J; Chadwick A; Lantos P L; Levy R; Rossor M N
Beta A4 protein deposition in familial Alzheimer's disease with the mutation in codon 717 of the beta A4 amyloid precursor protein gene and sporadic Alzheimer's disease.
Neuroscience letters 1993;149(2):137-40.
1992: Förstl H; Burns A; Luthert P; Cairns N; Lantos P; Levy R
Clinical and neuropathological correlates of depression in Alzheimer's disease.
Psychological medicine 1992;22(4):877-84.
1992: Cairns N J; Chadwick A; Luthert P J; Lantos P L
Astrocytosis, beta A4-protein deposition and paired helical filament formation in Alzheimer's disease.
Journal of the neurological sciences 1992;112(1-2):68-75.
1992: Förstl H; Burns A; Levy R; Cairns N; Luthert P; Lantos P
Neurologic signs in Alzheimer's disease. Results of a prospective clinical and neuropathologic study.
Archives of neurology 1992;49(10):1038-42.
1992: Förstl H; Burns A; Cairns N; Luthert P; Lantos P; Levy R
[Organic correlates of depressive symptoms in Alzheimer's dementia. Results of a prospective study, review of the literature]
Der Nervenarzt 1992;63(9):566-74.
1992: Goedert M; Spillantini M G; Cairns N J; Crowther R A
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms.
Neuron 1992;8(1):159-68.
1991: Cairns N J; Chadwick A; Luthert P J; Lantos P L
beta-Amyloid protein load is relatively uniform throughout neocortex and hippocampus in elderly Alzheimer's disease patients.
Neuroscience letters 1991;129(1):115-8.
1991: Förstl H; Cairns N; Burns A; Luthert P
Medical disorders in Alzheimer's disease and vascular dementia.
Postgraduate medical journal 1991;67(790):742-4.
1991: Hanger D P; Brion J P; Gallo J M; Cairns N J; Luthert P J; Anderton B H
Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated.
The Biochemical journal 1991;275 ( Pt 1)():99-104.
1991: Förstl H; Burns A; Luthert P; Cairns N
[Dementia and internal diseases: incidence of internal diseases in Alzheimer dementia, vascular dementia and other dementing diseases]
Zeitschrift für Gerontologie 1991;24(2):91-3.
1991: Armstrong R A; Myers D; Smith C U; Cairns N; Luthert P J
Alzheimer's disease: the relationship between the density of senile plaques, neurofibrillary tangles and A4 protein in human patients.
Neuroscience letters 1991;123(2):141-3.
1988: Cairns N J; Wonnacott S
[3H](-)nicotine binding sites in fetal human brain.
Brain research 1988;475(1):1-7.

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