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Nigel Cairns

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Richard A Armstrong; R L Hamilton; J Hedreen; I R A Mackenzie; Nigel J Cairns
Laminar distribution of the pathological changes in sporadic frontotemporal lobar degeneration with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy: a quantitative study using polynomial curve fitting.
Richard A Armstrong; Nigel J Cairns
Spatial patterns of the tau pathology in progressive supranuclear palsy.
Thomas J Esparza; David M Holtzman; Hanzhi Zhao; Randall J Bateman; Nigel J Cairns; John R Cirrito; David L Brody
Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls.

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2013: Richard A Armstrong; R L Hamilton; J Hedreen; I R A Mackenzie; Nigel J Cairns
Laminar distribution of the pathological changes in sporadic frontotemporal lobar degeneration with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy: a quantitative study using polynomial curve fitting.
Neuropathology and applied neurobiology 2013;39(4):335-47.
2013: Richard A Armstrong; Nigel J Cairns
Spatial patterns of the tau pathology in progressive supranuclear palsy.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2013;34(3):337-44.
2013: Thomas J Esparza; David M Holtzman; Hanzhi Zhao; Randall J Bateman; Nigel J Cairns; John R Cirrito; David L Brody
Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls.
Annals of neurology 2013;73(1):104-19.
2012: Richard A Armstrong; Nigel J Cairns
Different molecular pathologies result in similar spatial patterns of cellular inclusions in neurodegenerative disease: a comparative study of eight disorders.
Journal of neural transmission (Vienna, Austria : 1996) 2012;119(12):1551-60.
2012: Paul T Kotzbauer; Nigel J Cairns; Meghan C Campbell; Brad A Racette; Samer D Tabbal; Allison W Willis; Joel S Perlmutter
Pathologic accumulation of α-synuclein and Aβ in Parkinson disease patients with dementia.
Archives of neurology 2012;69(10):1326-31.
2012: Randall J Bateman; Tammie L S Benzinger; Tyler M Blazey; V Buckles; Nigel J Cairns; Anne M Fagan; Nick C Fox; Bernardino Ghetti; Alison Goate; David M Holtzman; William E Klunk; Daniel S Marcus; Ralph N Martins; Colin L Masters; Richard Mayeux; Eric McDade; John C Morris; Krista Moulder; Angela Oliver; John M Ringman; Martin N Rossor; Stephen Salloway; Anna Santacruz; Peter R Schofield; Reisa A Sperling; Xianyun Xie; Chengjie Xiong; Paul S Aisen
Clinical and biomarker changes in dominantly inherited Alzheimer's disease.
The New England journal of medicine 2012;367(9):795-804.
2012: Jessica M McDonald; Lisa Taylor-Reinwald; Nigel J Cairns; David Holtzman; Dominic M Walsh
The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain.
Brain research 2012;1450():138-47.
2012: Jianjun Sun; Jinbin Xu; Nigel J Cairns; Joel S Perlmutter; Robert H Mach
Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain.
PloS one 2012;7(11):e49483.
2012: Nupur Ghoshal; D F Wozniak; J T Dearborn; Nigel J Cairns
Core features of frontotemporal dementia recapitulated in progranulin knockout mice.
Neurobiology of disease 2012;45(1):395-408.
2011: Richard A Armstrong; Eileen H Bigio; Felix F Cruz-Sanchez; Charles Duyckaerts; Marla Gearing; Ian R A Mackenzie; Robert H Perry; Kari Skullerud; Hideaki Yokoo; Nigel J Cairns
Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID).
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(11):1651-7.
2011: Tristan Page; Robert H Perry; Eileen H Bigio; Nigel J Cairns; Deborah Carter; Sumi Chakraverty; Isidre Ferrer; Marla Gearing; Michael Gitcho; Alison M Goate; Sabrina Mosaheb; Julian R Thorpe
FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy.
Journal of molecular neuroscience : MN 2011;45(3):409-21.
2011: Ian R A Mackenzie; David G Munoz; Manuela Neumann; Nigel J Cairns; Adrian M Isaacs
Novel types of frontotemporal lobar degeneration: beyond tau and TDP-43.
Journal of molecular neuroscience : MN 2011;45(3):402-8.
2011: Rawan Tarawneh; Chengjie Xiong; Nigel J Cairns; Deborah Carter; Gina D'Angelo; Anne M Fagan; Denise Head; Jack H Ladenson; Jin-Moo Lee; Elizabeth Macy; Mark A Mintun; John C Morris; David M Holtzman
Visinin-like protein-1: diagnostic and prognostic biomarker in Alzheimer disease.
Annals of neurology 2011;70(2):274-85.
2011: Richard A Armstrong; Nigel J Cairns
Spatial patterns of TDP-43 neuronal cytoplasmic inclusions (NCI) in fifteen cases of frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP).
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2011;32(4):653-9.
2011: Florence Dequen; Eileen H Bigio; Nigel J Cairns; Jean-Pierre Julien
Gigaxonin mutation analysis in patients with NIFID.
Neurobiology of aging 2011;32(8):1528-9.
2011: Adam C Naj; Gyungah Jun; Gary Beecham; Li-San Wang; Badri Narayan Vardarajan; Jacqueline Buros; Paul J Gallins; Joseph Buxbaum; Gail P Jarvik; Paul K Crane; Eric B Larson; Thomas D Bird; Bradley F Boeve; Neill R Graff-Radford; Philip L De Jager; Denis Evans; Julie A Schneider; Minerva M Carrasquillo; Nilufer Ertekin-Taner; Steven G Younkin; Carlos Cruchaga; John S K Kauwe; Petra Nowotny; Patricia Kramer; John Hardy; Matthew Huentelman; Amanda Myers; M. Michael Barmada; F Yesim Demirci; Clinton T Baldwin; Robert C Green; Ekaterina Rogaeva; Steven E Arnold; Robert C Barber; Thomas Beach; Eileen H Bigio; James D Bowen; Adam Boxer; James R Burke; Nigel J Cairns; Chris S Carlson; Regina M Carney; Steven L Carroll; Helena C Chui; David G Clark; Jason Corneveaux; Carl W Cotman; Jeffrey L Cummings; Charles DeCarli; Steven T DeKosky; Ramon Diaz-Arrastia; Malcolm Dick; dennis dickson; William G Ellis; Kelley M Faber; Kenneth B Fallon; Martin R Farlow; Steven Ferris; Matthew P Frosch; Douglas Galasko; Mary Ganguli; Marla Gearing; Daniel Geschwind; Bernardino Ghetti; John Gilbert; Sid Gilman; Bruno Giordani; Jonathan D Glass; John H Growdon; Ronald L Hamilton; Lindy E Harrell; Elizabeth Head; Lawrence Honig; Christine M Hulette; Bradley T Hyman; Gregory A Jicha; Lee-Way Jin; Nancy Johnson; Jason Karlawish; Anna Karydas; Jeffrey A Kaye; Ronald Kim; Edward H Koo; Neil W Kowall; James J Lah; Allan Levey; Andrew P Lieberman; Oscar L Lopez; Wendy J Mack; Daniel C Marson; Frank Martiniuk; Deborah C Mash; Eliezer Masliah; Wayne C McCormick; Susan M McCurry; Andrew N McDavid; Ann C McKee; Marsel Mesulam; Bruce L Miller; Carol A Miller; Joshua Miller; Joseph E Parisi; Daniel P Perl; Elaine Peskind; Ronald C. Petersen; Wayne W Poon; Joseph F Quinn; Ruchita A Rajbhandary; Murray Raskind; Barry Reisberg; John M Ringman; Erik D Roberson; Roger N Rosenberg; Mary Sano; Lon S Schneider; William Seeley; Michael L Shelanski; Michael Slifer; Charles D Smith; Joshua A Sonnen; Salvatore Spina; Robert A Stern; Rudolph E Tanzi; John Q Trojanowski; Juan C Troncoso; Vivianna M Van Deerlin; Harry V Vinters; Jean Paul Vonsattel; Sandra Weintraub; Kathleen A Welsh-Bohmer; Jennifer Williamson; Randall L Woltjer; Laura B Cantwell; Beth A Dombroski; Duane Beekly; Kathryn L Lunetta; Eden R Martin; M Ilyas Kamboh; Andrew J Saykin; Eric Reiman; David A Bennett; John C Morris; Thomas J Montine; Alison Goate; Deborah Blacker; Debby W Tsuang; Hakon Hakonarson; Walter A Kukull; Tatiana M Foroud; Jonathan L Haines; Richard Mayeux; Margaret Pericak-Vance; Lindsay A Farrer; Peter St George-Hyslop; Gerard D Schellenberg
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Nature genetics 2011;43(5):436-41.
2011: Alice S Chen-Plotkin; Maria Martinez-Lage; Patrick M A Sleiman; William Hu; Robert Greene; Elisabeth McCarty Wood; Shaoxu Bing; Murray Grossman; Gerard D Schellenberg; Kimmo J Hatanpaa; Myron F Weiner; Charles L White; William S Brooks; Glenda M Halliday; Jillian J Kril; Marla Gearing; Thomas Beach; Neill R Graff-Radford; dennis dickson; Rosa Rademakers; Bradley F Boeve; Stuart M Pickering-Brown; Julie Snowden; John C van Swieten; Peter Heutink; Harro Seelaar; Jill R Murrell; Bernardino Ghetti; Salvatore Spina; Jordan Grafman; Jeffrey A Kaye; Randall L Woltjer; Marsel Mesulam; Eileen Bigio; Albert Lladó; Bruce L Miller; Ainhoa Alzualde; Fermin Moreno; Jonathan D Rohrer; Ian R A Mackenzie; Howard H Feldman; Ronald L Hamilton; Marc Cruts; Sebastiaan Engelborghs; Peter P De Deyn; Christine Van Broeckhoven; Thomas D Bird; Nigel J Cairns; Alison Goate; Matthew P Frosch; Peter F Riederer; Nenad Bogdanovic; Virginia M-Y Lee; John Q Trojanowski; Vivianna M Van Deerlin
Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration.
Archives of neurology 2011;68(4):488-97.
2011: Richard A Armstrong; Nigel J Cairns
A morphometric study of the spatial patterns of TDP-43 immunoreactive neuronal inclusions in frontotemporal lobar degeneration (FTLD) with progranulin (GRN) mutation.
Histology and histopathology 2011;26(2):185-90.
2011: Ian R A Mackenzie; David G Munoz; Hirofumi Kusaka; Osamu Yokota; Kenji Ishihara; Sigrun Roeber; Hans A Kretzschmar; Nigel J Cairns; Manuela Neumann
Distinct pathological subtypes of FTLD-FUS.
Acta neuropathologica 2011;121(2):207-18.
2011: Richard A Armstrong; Marla Gearing; Eileen H Bigio; Felix F Cruz-Sanchez; Charles Duyckaerts; Ian R A Mackenzie; Robert H Perry; Kari Skullerud; Hedeaki Yokoo; Nigel J Cairns
The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease.
Acta neuropathologica 2011;121(2):219-28.
2011: Lirong Zhu; Samer D Tabbal; Nigel J Cairns; Brad A Racette
Pregnancy in multiple system atrophy: a case report.
Journal of medical case reports 2011;5(1):599.
2010: Nigel J Cairns; R J Perrin; R E Schmidt; A Gru; Karen G Green; D Carter; Lisa Taylor-Reinwald; John C Morris; Michael Gitcho; Robert H Baloh
TDP-43 proteinopathy in familial motor neurone disease with TARDBP A315T mutation: a case report.
Neuropathology and applied neurobiology 2010;36(7):673-9.
2010: Rebecca Craig-Schapiro; Richard J Perrin; Catherine M Roe; Chengjie Xiong; Deborah Carter; Nigel J Cairns; Mark A Mintun; Elaine Peskind; Ge Li; Douglas Galasko; Christopher M Clark; Joseph F Quinn; Gina D'Angelo; James P Malone; R Reid Townsend; John C Morris; Anne M Fagan; David M Holtzman
YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease.
Biological psychiatry 2010;68(10):903-12.
2010: Erin R Foster; Meghan C Campbell; Michelle A Burack; Johanna Hartlein; Hubert P Flores; Nigel J Cairns; Tamara Hershey; Joel S Perlmutter
Amyloid imaging of Lewy body-associated disorders.
Movement disorders : official journal of the Movement Disorder Society 2010;25(15):2516-23.
2010: Wen-Quan Zou; Gianfranco Puoti; Xiangzhu Xiao; Jue Yuan; Liuting Qing; Ignazio Cali; Miyuki Shimoji; Jan P M Langeveld; Rudy J Castellani; Silvio Notari; Barbara J Crain; Robert E Schmidt; Michael Geschwind; Stephen J DeArmond; Nigel J Cairns; dennis dickson; Lawrence Honig; Juan Maria Torres; James A Mastrianni; Sabina Capellari; Giorgio Giaccone; Ermias D Belay; Lawrence B Schonberger; Mark Cohen; George Perry; Qingzhong Kong; Piero Parchi; Fabrizio Tagliavini; Pierluigi Gambetti
Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.
Annals of neurology 2010;68(2):162-72.
2010: Nigel J Cairns; Lisa Taylor-Reinwald; John C Morris
Autopsy consent, brain collection, and standardized neuropathologic assessment of ADNI participants: the essential role of the neuropathology core.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(3):274-9.
2010: Michael Weiner; Paul S Aisen; Clifford R Jack; William J Jagust; John Q Trojanowski; Leslie Shaw; Andrew J. Saykin; John C Morris; Nigel J Cairns; Laurel Beckett; Arthur W Toga; Robert Green; Sarah Walter; Holly Soares; Peter Snyder; Eric Siemers; William Potter; Patricia E Cole; Mark Schmidt
The Alzheimer's disease neuroimaging initiative: progress report and future plans.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(3):202-11.e7.
2010: Richard A Armstrong; Nigel J Cairns
Analysis of beta-amyloid (Abeta) deposition in the temporal lobe in Alzheimer's disease using Fourier (spectral) analysis.
Neuropathology and applied neurobiology 2010;36(3):248-57.
2010: Vivianna M Van Deerlin; Patrick M A Sleiman; Maria Martinez-Lage; Alice Chen-Plotkin; Li-San Wang; Neill R Graff-Radford; dennis dickson; Rosa Rademakers; Bradley F Boeve; Murray Grossman; Steven E Arnold; D M A Mann; Stuart M Pickering-Brown; Harro Seelaar; Peter Heutink; John C van Swieten; Jill R Murrell; Bernardino Ghetti; Salvatore Spina; Jordan Grafman; John R Hodges; Maria Grazia Spillantini; Sid Gilman; Andrew P Lieberman; Jeffrey A Kaye; Randall L Woltjer; Eileen H Bigio; Marsel Mesulam; Safa Al-Sarraj; Claire Troakes; Roger N Rosenberg; Charles L White; Isidro Ferrer; Albert Lladó; Manuela Neumann; Hans A Kretzschmar; Christine Marie Hulette; Kathleen A Welsh-Bohmer; Bruce L Miller; Ainhoa Alzualde; Adolfo Lopez de Munain; Ann C McKee; Marla Gearing; Allan Levey; James J Lah; John Hardy; Jonathan D Rohrer; Tammaryn Lashley; Ian R A Mackenzie; Howard H Feldman; Ronald L Hamilton; Steven T DeKosky; Julie van der Zee; Samir Kumar-Singh; Christine Van Broeckhoven; Richard Mayeux; Jean Paul G Vonsattel; Juan C Troncoso; Jillian J Kril; John B J Kwok; Glenda M Halliday; Thomas D Bird; Paul Geoffrey Ince; Pamela J Shaw; Nigel J Cairns; John C Morris; Catriona Ann McLean; Charles DeCarli; William G Ellis; Stefanie H Freeman; Matthew P Frosch; John H Growdon; Daniel P Perl; Mary Sano; David A Bennett; Julie A Schneider; Thomas Beach; Eric Reiman; Bryan Woodruff; Jeffrey L Cummings; Harry V Vinters; Carol A Miller; Helena C Chui; Irina Alafuzoff; Päivi Hartikainen; Danielle Seilhean; Douglas Galasko; Eliezer Masliah; Carl W Cotman; M Teresa Tuñón; M Cristina Caballero Martínez; David G Munoz; Steven L Carroll; Daniel Marson; Peter F Riederer; Nenad Bogdanovic; Gerard D Schellenberg; Hakon Hakonarson; John Q Trojanowski; Virginia M-Y Lee
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Nature genetics 2010;42(3):234-9.
2010: Nigel J Cairns; Nupur Ghoshal
FUS: A new actor on the frontotemporal lobar degeneration stage.
Neurology 2010;74(5):354-6.
2010: Richard A Armstrong; William G Ellis; Ronald L Hamilton; Ian R A Mackenzie; John Hedreen; Marla Gearing; Thomas Montine; Jean-Paul Vonsattel; Elizabeth Head; Andrew P Lieberman; Nigel J Cairns
Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(2):227-39.
2010: M A Burack; J Hartlein; H P Flores; L Taylor-Reinwald; J S Perlmutter; Nigel J Cairns
In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia.
Neurology 2010;74(1):77-84.
2010: Ian R A Mackenzie; Manuela Neumann; Eileen H Bigio; Nigel J Cairns; Irina Alafuzoff; Jillian Kril; Gabor Geza Kovacs; Bernardino Ghetti; Glenda Halliday; Ida E Holm; Paul Geoffrey Ince; Wouter Kamphorst; Tamas Revesz; Annemieke J M Rozemuller; Samir Kumar-Singh; Haruhiko Akiyama; Atik Baborie; Salvatore Spina; dennis dickson; John Q Trojanowski; D M A Mann
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update.
Acta neuropathologica 2010;119(1):1-4.
2009: Nigel J Cairns; Milos D Ikonomovic; Tammie Benzinger; Martha Storandt; Anne M Fagan; Aarti R Shah; Lisa Taylor Reinwald; Deborah Carter; Angela Felton; David M Holtzman; Mark A Mintun; William E Klunk; John C Morris
Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report.
Archives of neurology 2009;66(12):1557-62.
2009: Richard A Armstrong; Nigel J Cairns
Size frequency distribution of the beta-amyloid (abeta) deposits in dementia with Lewy bodies with associated Alzheimer's disease pathology.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2009;30(6):471-7.
2009: Iga Wegorzewska; Shaughn Bell; Nigel J Cairns; Timothy M Miller; Robert H Baloh
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18809-14.
2009: Michael A Gitcho; Eileen H Bigio; Manjari Mishra; Nancy Johnson; Sandra Weintraub; Marsel Mesulam; Rosa Rademakers; Sumi Chakraverty; Carlos Cruchaga; John C Morris; Alison Goate; Nigel J Cairns
TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy.
Acta neuropathologica 2009;118(5):633-45.
2009: Richard A Armstrong; Nigel J Cairns
Laminar distribution of the pathological changes in frontal and temporal cortex in 8 patients with progressive supranuclear palsy.
Clinical neuropathology 2009;28(5):350-7.
2009: Richard A Armstrong; Nigel J Cairns
Clustering and spatial correlations of the neuronal cytoplasmic inclusions, astrocytic plaques and ballooned neurons in corticobasal degeneration.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(9):1103-10.
2009: J B Norton; Nigel J Cairns; Sumi Chakraverty; J Wang; D Levitch; James E Galvin; Alison Goate
Presenilin1 G217R mutation linked to Alzheimer disease with cotton wool plaques.
Neurology 2009;73(6):480-2.
2009: Michael A Gitcho; Jeffrey Strider; Deborah Carter; Lisa Taylor-Reinwald; Mark S Forman; Alison Goate; Nigel J Cairns
VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death.
The Journal of biological chemistry 2009;284(18):12384-98.
2009: Sara Rollinson; Patrizia Rizzu; Stephen Sikkink; Matthew Baker; Nicola Halliwell; Julie Snowden; Bryan Joseph Traynor; Dina Ruano; Nigel J Cairns; Jonathan D Rohrer; Simon Mead; John Collinge; Martin N Rossor; Ela Akay; Rita Guerreiro; Rosa Rademakers; Karen E Morrison; Pau Pastor; Elena Alonso; Pablo Martinez-Lage; Neil Graff-Radford; David Neary; Peter Heutink; D M A Mann; John Van Swieten; Stuart Pickering-Brown
Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration.
Neurobiology of aging 2009;30(4):656-65.
2009: Richard A Armstrong; James W Ironside; Peter L Lantos; Nigel J Cairns
A quantitative study of the pathological changes in the cerebellum in 15 cases of variant Creutzfeldt-Jakob disease (vCJD).
Neuropathology and applied neurobiology 2009;35(1):36-45.
2009: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Hippocampal pathology in progressive supranuclear palsy (PSP): a quantitative study of 8 cases.
Clinical neuropathology 2009;28(1):46-53.
2009: Ian R A Mackenzie; Manuela Neumann; Eileen H Bigio; Nigel J Cairns; Irina Alafuzoff; Jillian Kril; Gabor Geza Kovacs; Bernardino Ghetti; Glenda Halliday; Ida E Holm; Paul Geoffrey Ince; Wouter Kamphorst; Tamas Revesz; Annemieke J M Rozemuller; Samir Kumar-Singh; Haruhiko Akiyama; Atik Baborie; Salvatore Spina; dennis dickson; John Q Trojanowski; D M A Mann
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations.
Acta neuropathologica 2009;117(1):15-8.
2008: Julian R Thorpe; Helen Tang; Joe Atherton; Nigel J Cairns
Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(12):1661-71.
2008: Rajka Liscic; L T Grinberg; J Zidar; M A Gitcho; Nigel J Cairns
ALS and FTLD: two faces of TDP-43 proteinopathy.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2008;15(8):772-80.
2008: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
What determines the molecular composition of abnormal protein aggregates in neurodegenerative disease?
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(4):351-65.
2008: Xian Nan Tang; B Cairns; Nigel J Cairns; Midori A Yenari
Apocynin improves outcome in experimental stroke with a narrow dose range.
Neuroscience 2008;154(2):556-62.
2008: Catherine M Roe; Chengjie Xiong; Philip Miller; Nigel J Cairns; John C Morris
Interaction of neuritic plaques and education predicts dementia.
Alzheimer disease and associated disorders 2008;22(2):188-93.
2008: Kimmo J Hatanpaa; Eileen H Bigio; Nigel J Cairns; Kyle B Womack; Sandra Weintraub; John C Morris; Chan Foong; Guanghua Xiao; Christa L Hladik; Tina Y Mantanona; Charles L White
TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study.
Journal of neuropathology and experimental neurology 2008;67(4):271-9.
2008: Michael A Gitcho; Robert H Baloh; Sumi Chakraverty; Kevin Mayo; Joanne B Norton; Denise Levitch; Kimmo J Hatanpaa; Charles L White; Eileen H Bigio; Richard Caselli; Matt Baker; Muhammad T Al-Lozi; John C Morris; Alan Pestronk; Rosa Rademakers; Alison Goate; Nigel J Cairns
TDP-43 A315T mutation in familial motor neuron disease.
Annals of neurology 2008;63(4):535-8.
2008: Odity Mukherjee; Jun Wang; Michael Gitcho; Sumi Chakraverty; Lisa Taylor-Reinwald; Shantia Shears; John S K Kauwe; Joanne Norton; Denise Levitch; Eileen H Bigio; Kimmo J Hatanpaa; Charles L White; John C Morris; Nigel J Cairns; Alison Goate
Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia.
Human mutation 2008;29(4):512-21.
2008: Yonghong Li; Andrew Grupe; Charles Rowland; Peter Holmans; Ricardo Segurado; Richard Abraham; Lesley Jones; Joseph J Catanese; David Ross; Kevin Mayo; Maribel Martinez; Paul Hollingworth; Alison Goate; Nigel J Cairns; Brad A Racette; Joel S Perlmutter; Michael C O'Donovan; John C Morris; Carol Brayne; David C Rubinsztein; Simon Lovestone; Leon J Thal; Michael J Owen; Julie Williams
Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Human molecular genetics 2008;17(5):759-67.
2008: Nigel J Cairns
Neuronal intermediate filament inclusion disease.
Handbook of clinical neurology 2008;89():443-8.
2008: Franz J Wippold; Nigel J Cairns; Katie D Vo; David M Holtzman; John C Morris
Neuropathology for the neuroradiologist: plaques and tangles.
AJNR. American journal of neuroradiology 2008;29(1):18-22.
2007: Yan Hu; Ava Hosseini; John S K Kauwe; Julia Gross; Nigel J Cairns; Alison Goate; Anne M Fagan; R Reid Townsend; David M Holtzman
Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease.
Proteomics. Clinical applications 2007;1(11):1373-84.
2007: Nigel J Cairns; Manuela Neumann; Eileen H Bigio; Ida E Holm; Dirk Troost; Kimmo J Hatanpaa; Chan Foong; Charles L White; Julie A Schneider; Hans A Kretzschmar; Deborah Carter; Lisa Taylor-Reinwald; Katherine Paulsmeyer; Jeffrey Strider; Michael Gitcho; Alison Goate; John C Morris; Manjari Mishra; Linda K Kwong; Anna Stieber; Yan Xu; Mark S Forman; John Q Trojanowski; Virginia M-Y Lee; Ian R A Mackenzie
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
The American journal of pathology 2007;171(1):227-40.
2007: Nigel J Cairns; Eileen H Bigio; Ian R A Mackenzie; Manuela Neumann; Virginia M-Y Lee; Kimmo J Hatanpaa; Charles L White; Julie A Schneider; Lea Tenenholz Grinberg; Glenda Halliday; Charles Duyckaerts; James S Lowe; Ida E Holm; Markus Tolnay; Koichi Okamoto; Hideaki Yokoo; Shigeo Murayama; John Woulfe; David G Munoz; dennis dickson; Paul Geoffrey Ince; John Q Trojanowski; D M A Mann
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Acta neuropathologica 2007;114(1):5-22.
2007: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
A quantitative study of the pathological changes in white matter in multiple system atrophy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2007;27(3):221-7.
2007: Ian R A Mackenzie; Eileen H Bigio; Paul Geoffrey Ince; Felix Geser; Manuela Neumann; Nigel J Cairns; Linda K Kwong; Mark S Forman; John Ravits; Heather Stewart; Andrew Eisen; Leo McClusky; Hans A Kretzschmar; Camelia M Monoranu; J Robin Highley; Janine Kirby; Teepu Siddique; Pamela J Shaw; Virginia M-Y Lee; John Q Trojanowski
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Annals of neurology 2007;61(5):427-34.
2007: Rajka Liscic; Martha Storandt; Nigel J Cairns; John C Morris
Clinical and psychometric distinction of frontotemporal and Alzheimer dementias.
Archives of neurology 2007;64(4):535-40.
2007: Manuela Neumann; Ian R A Mackenzie; Nigel J Cairns; Philip J Boyer; William R Markesbery; Charles D Smith; J. Paul Taylor; Hans A Kretzschmar; Virginia E Kimonis; Mark S Forman
TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations.
Journal of neuropathology and experimental neurology 2007;66(2):152-7.
2007: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Spatial topography of the neurofibrillary tangles in cortical and subcortical regions in progressive supranuclear palsy.
Parkinsonism & related disorders 2007;13(1):50-4.
2007: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Progressive supranuclear palsy (PSP): a quantitative study of the pathological changes in cortical and subcortical regions of eight cases.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(12):1569-77.
2007: Maria I Behrens; Odity Mukherjee; Pang-hsien Tu; Rajka Liscic; Lea Tenenholz Grinberg; Deborah Carter; Katherine Paulsmeyer; Lisa Taylor-Reinwald; Michael Gitcho; Joanne B Norton; Sumi Chakraverty; Alison Goate; John C Morris; Nigel J Cairns
Neuropathologic heterogeneity in HDDD1: a familial frontotemporal lobar degeneration with ubiquitin-positive inclusions and progranulin mutation.
Alzheimer disease and associated disorders 2007;21(1):1-7.
2007: Richard A Armstrong; Nigel J Cairns
Spatial patterns of the pathological changes in neuronal intermediate filament inclusion disease (NIFID): an alpha-internexin immunohistochemical study.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(4):451-6.
2006: Marian Lumbreras; Carmela Baamonde; Carmen Martínez-Cué; Gert Lubec; Nigel J Cairns; Joan Sallés; Mara Dierssen; Jesús Flórez
Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease.
Amino acids 2006;31(4):449-56.
2006: Richard A Armstrong; Nigel J Cairns
Laminar degeneration of the frontal and temporal cortex in neuronal intermediate filament inclusion disease (NIFID): a study original using alpha-internexin immunohistochemistry.
Clinical neuropathology 2006;25(5):209-15.
2006: Odity Mukherjee; Pau Pastor; Nigel J Cairns; Sumi Chakraverty; John S K Kauwe; Shantia Shears; Maria I Behrens; John Budde; Anthony L Hinrichs; Joanne Norton; Denise Levitch; Lisa Taylor-Reinwald; Michael Gitcho; Pang-hsien Tu; Lea Tenenholz Grinberg; Rajka Liscic; Javier Armendariz; John C Morris; Alison Goate
HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin.
Annals of neurology 2006;60(3):314-22.
2006: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Multiple system atrophy (MSA): topographic distribution of the alpha-synuclein-associated pathological changes.
Parkinsonism & related disorders 2006;12(6):356-62.
2006: Richard A Armstrong; Emilia Kerty; K Skullerud; Nigel J Cairns
Neuropathological changes in ten cases of neuronal intermediate filament inclusion disease (NIFID): a study using alpha-internexin immunohistochemistry and principal components analysis (PCA).
Journal of neural transmission (Vienna, Austria : 1996) 2006;113(9):1207-15.
2006: Richard A Armstrong; Nigel J Cairns; James W Ironside
Size frequency distributions of the florid prion protein aggregates in variant Creutzfeldt-Jakob disease follow a power-law function.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2006;27(2):104-9.
2006: Mark S Forman; Ian R A Mackenzie; Nigel J Cairns; Eric Swanson; Philip J Boyer; David Drachman; Bharati S Jhaveri; Jason H T Karlawish; Alan Pestronk; Thomas W Smith; Pang-hsien Tu; Giles D J Watts; William R Markesbery; Charles D Smith; Virginia E Kimonis
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations.
Journal of neuropathology and experimental neurology 2006;65(6):571-81.
2006: Lida Hashemzadeh-Bonehi; Roger Guy Phillips; Nigel J Cairns; Sabrina Mosaheb; Julian R Thorpe
Pin1 protein associates with neuronal lipofuscin: potential consequences in age-related neurodegeneration.
Experimental neurology 2006;199(2):328-38.
2006: Richard A Armstrong; Nigel J Cairns
Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2006;13(5):528-32.
2006: Parastoo Momeni; Nigel J Cairns; Robert H Perry; Eileen H Bigio; Marla Gearing; Andrew Singleton; John Hardy
Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID).
Neurobiology of aging 2006;27(5):778.e1-778.e6.
2006: Parastoo Momeni; Jennifer C Schymick; Shushant Jain; Mark Cookson; Nigel J Cairns; Elisa Greggio; Matthew J Greenway; Stephen Berger; Stuart Pickering-Brown; Adriano Chio; Hon-Chung Fung; David M Holtzman; Edward D Huey; Eric M Wassermann; Jennifer Adamson; Michael Hutton; Ekaterina Rogaeva; Peter St George-Hyslop; Jeffrey rothstein; Orla Hardiman; Jordan Grafman; Andrew Singleton; John Hardy; Bryan Joseph Traynor
Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD.
BMC neurology 2006;6():44.
2006: Nigel J Cairns; Eileen H Bigio; Ian R A Mackenzie
Letter to the editor.
Journal of neuropathology and experimental neurology 2006;65(1):97; author reply 97-8.
2005: Nigel J Cairns; Richard A Armstrong
Spatial patterns of the pathological changes in the temporal lobe of patients with neuronal intermediate filament inclusion disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2005;25(4):298-303.
2005: Richard A Armstrong; Nigel J Cairns; James W Ironside; Peter L Lantos
Size frequency distribution of prion protein (PrP) aggregates in variant Creutzfeldt-Jakob disease (vCJD).
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(11):1565-73.
2005: Sabrina Mosaheb; Julian R Thorpe; Lida Hashemzadeh-Bonehi; Eileen H Bigio; Marla Gearing; Nigel J Cairns
Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease.
Acta neuropathologica 2005;110(4):360-8.
2005: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Multiple system atrophy: laminar distribution of the pathological changes in frontal and temporal neocortex--a study in ten patients.
Clinical neuropathology 2005;24(5):230-5.
2005: Payam Rezaie; Charlie C Pontikis; Lance Hudson; Nigel J Cairns; Peter L Lantos
Expression of cellular prion protein in the frontal and occipital lobe in Alzheimer's disease, diffuse Lewy body disease, and in normal brain: an immunohistochemical study.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(8):929-40.
2005: Satoru Sudo; Masaki Shiozawa; Nigel J Cairns; Yuji Wada
Aberrant accentuation of neurofibrillary degeneration in the hippocampus of Alzheimer's disease with amyloid precursor protein 717 and presenilin-1 gene mutations.
Journal of the neurological sciences 2005;234(1-2):55-65.
2005: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Overlap between neurodegenerative disorders.
Neuropathology : official journal of the Japanese Society of Neuropathology 2005;25(2):111-24.
2005: Mia E-L Blomqvist; Katy Chalmers; Niels Andreasen; Nenad Bogdanovic; Gordon K Wilcock; Nigel J Cairns; Lars Feuk; Anthony J Brookes; Seth Love; Kaj Blennow; Pat Kehoe; Jonathan A Prince
Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.
Neurobiology of aging 2005;26(6):795-802.
2005: Nigel J Cairns; RA Armstrong
Spatial correlations between the neuronal inclusions, swollen achromatic neurons, and glial cells in neuronal intermediate filament inclusion disease (NIFID).
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(4):473-80.
2005: Sarra E Jamieson; Jacqueline K White; Joanna M M Howson; Rebecca Pask; Anne N Smith; Carol Brayne; John Grimley Evans; John H Xuereb; Nigel J Cairns; David C Rubinsztein; Jenefer M Blackwell
Candidate gene association study of solute carrier family 11a members 1 (SLC11A1) and 2 (SLC11A2) genes in Alzheimer's disease.
Neuroscience letters 2005;374(2):124-8.
2005: Lynnette J Cook; Luk W Ho; Lin Wang; Edith Terrenoire; Carol Brayne; John Grimley Evans; John H Xuereb; Nigel J Cairns; Darko Turic; Paul Hollingworth; Pamela J Moore; Luke Jehu; Nicola Archer; Sarah Walter; Catherine Foy; Amanda Edmondson; John Powell; Simon Lovestone; Julie Williams; David C Rubinsztein
Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):5-8.
2004: Nigel J Cairns; Virginia M-Y Lee; John Q Trojanowski
The cytoskeleton in neurodegenerative diseases.
The Journal of pathology 2004;204(4):438-49.
2004: Julian R Thorpe; Sabrina Mosaheb; Lida Hashemzadeh-Bonehi; Nigel J Cairns; John E Kay; Simon J Morley; Stuart L Rulten
Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias.
Neurobiology of disease 2004;17(2):237-49.
2004: Nigel J Cairns; Murray Grossman; Steven E Arnold; David J Burn; Evelyn Jaros; Robert H Perry; Charles Duyckaerts; B Stankoff; B Pillon; Kari Skullerud; F F Cruz-Sanchez; Eileen H Bigio; Ian R A Mackenzie; Marla Gearing; Jorge L Juncos; Jonathan D Glass; Hideaki Yokoo; Yoichi Nakazato; Sabrina Mosaheb; Julian R Thorpe; Kunihiro Uryu; Virginia M-Y Lee; John Q Trojanowski
Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease.
Neurology 2004;63(8):1376-84.
2004: Katrin Schuessel; Silke Leutner; Nigel J Cairns; Walter E Müller; Anne Eckert
Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(9):1167-82.
2004: Nigel J Cairns; Kunihiro Uryu; Eileen H Bigio; Ian R A Mackenzie; Marla Gearing; Charles Duyckaerts; Hideaki Yokoo; Yoichi Nakazato; Evelyn Jaros; Robert H Perry; Steven E Arnold; Virginia M-Y Lee; John Q Trojanowski
alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases.
Acta neuropathologica 2004;108(3):213-23.
2004: Nigel J Cairns; Victoria Zhukareva; Kunihiro Uryu; Bin Zhang; Eileen H Bigio; Ian R A Mackenzie; Marla Gearing; Charles Duyckaerts; Hideaki Yokoo; Yoichi Nakazato; Evelyn Jaros; Robert H Perry; Virginia M-Y Lee; John Q Trojanowski
alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease.
The American journal of pathology 2004;164(6):2153-61.
2004: Nigel J Cairns; RA Armstrong
Quantification of the pathological changes in the temporal lobe of patients with a novel neurofilamentopathy: neurofilament inclusion disease (NID).
Clinical neuropathology 2004;23(3):107-12.
2004: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
A quantitative study of the pathological changes in ten patients with multiple system atrophy (MSA).
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(4):485-95.
2004: Hagit Katzov; Katy Chalmers; Juni Palmgren; Niels Andreasen; Boo Johansson; Nigel J Cairns; Margaret Gatz; Gordon K Wilcock; Seth Love; Nancy L Pedersen; Anthony J Brookes; Kaj Blennow; Pat Kehoe; Jonathan A Prince
Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.
Human mutation 2004;23(4):358-67.
2004: Pat Kehoe; Hagit Katzov; Niels Andreasen; Margaret Gatz; Gordon K Wilcock; Nigel J Cairns; Juni Palmgren; Ulf de Faire; Anthony J Brookes; Nancy L Pedersen; Kaj Blennow; Jonathan A Prince
Common variants of ACE contribute to variable age-at-onset of Alzheimer's disease.
Human genetics 2004;114(5):478-83.
2004: Lynnette J Cook; Luk W Ho; Alison E Taylor; Carol Brayne; John Grimley Evans; John H Xuereb; Nigel J Cairns; Antonia Pritchard; Helen Lemmon; D M A Mann; David St Clair; Darko Turic; Paul Hollingworth; Pamela J Moore; Luke Jehu; Nicola Archer; Sarah Walter; Catherine Foy; Amanda Edmondson; John Powell; Simon Lovestone; Michael J Owen; Julie Williams; Corinne Lendon; David C Rubinsztein
Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.
Neuroscience letters 2004;358(2):142-6.
2004: Paul Preece; David J Virley; Moheb Costandi; Robert Coombes; Stephen J Moss; Anne W Mudge; Elena Jazin; Nigel J Cairns
Amyloid precursor protein mRNA levels in Alzheimer's disease brain.
Brain research. Molecular brain research 2004;122(1):1-9.
2004: Nigel J Cairns; Evelyn Jaros; Robert H Perry; RA Armstrong
Temporal lobe pathology of human patients with neurofilament inclusion disease.
Neuroscience letters 2004;354(3):245-7.
2004: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Spatial patterns of alpha-synuclein positive glial cytoplasmic inclusions in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2004;19(1):109-12.
2003: Richard A Armstrong; Peter L Lantos; James W Ironside; Nigel J Cairns
Spatial correlation between the vacuolation, prion protein, deposition and surviving neurons in patients with Creutzfeldt-Jakob disease (vCJD).
Journal of neural transmission (Vienna, Austria : 1996) 2003;110(11):1303-11.
2003: Paul Preece; Nigel J Cairns
Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance.
Brain research. Molecular brain research 2003;118(1-2):60-71.
2003: Doris Culpan; Sian H MacGowan; Julia M Ford; Nicoll James; W Sue Griffin; Deborah Dewar; Nigel J Cairns; Anthony Hughes; Pat Kehoe; Gordon K Wilcock
Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.
Neuroscience letters 2003;350(1):61-5.
2003: Richard A Armstrong; Nigel J Cairns; James W Ironside; Peter L Lantos
Does the neuropathology of human patients with variant Creutzfeldt-Jakob disease reflect haematogenous spread of the disease?
Neuroscience letters 2003;348(1):37-40.
2003: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
A quantitative study of the pathological changes in cortical neurons in sporadic Creutzfeldt-Jakob disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(3):181-7.
2003: Richard A Armstrong; Peter L Lantos; James W Ironside; Nigel J Cairns
Differences in the density and spatial distribution of florid and diffuse plaques in variant Creutzfeldt-Jakob disease (vCJD).
Clinical neuropathology 2003;22(5):209-14.
2003: Paul Preece; David J Virley; Moheb Costandi; Robert Coombes; Stephen J Moss; Anne W Mudge; Elena Jazin; Nigel J Cairns
Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease.
Brain research. Molecular brain research 2003;116(1-2):155-8.
2003: Paul Preece; David J Virley; Moheb Costandi; Robert Coombes; Stephen J Moss; Anne W Mudge; Elena Jazin; Nigel J Cairns
An optimistic view for quantifying mRNA in post-mortem human brain.
Brain research. Molecular brain research 2003;116(1-2):7-16.
2003: Tibor Kovács; Mátyás I Papp; Nigel J Cairns; M Nadeem Khan; Peter L Lantos
Olfactory bulb in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2003;18(8):938-42.
2003: Nigel J Cairns; R A Armstrong
Clustering of neuronal inclusions in "dementia with neurofilament inclusions".
Acta neuropathologica 2003;106(2):125-8.
2003: Nigel J Cairns; T Brännström; M N Khan; Martin N Rossor; Peter L Lantos
Neuronal loss in familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions.
Experimental neurology 2003;181(2):319-26.
2003: Nigel J Cairns; Robert H Perry; Evelyn Jaros; David J Burn; Ian G McKeith; James S Lowe; Janice Holton; Martin N Rossor; Kari Skullerud; Charles Duyckaerts; Felix F Cruz-Sanchez; Peter L Lantos
Patients with a novel neurofilamentopathy: dementia with neurofilament inclusions.
Neuroscience letters 2003;341(3):177-80.
2003: Pat Kehoe; Hagit Katzov; Lars Feuk; Anna M Bennet; Boo Johansson; Björn Wiman; Ulf de Faire; Nigel J Cairns; Gordon K Wilcock; Anthony J Brookes; Kaj Blennow; Jonathan A Prince
Haplotypes extending across ACE are associated with Alzheimer's disease.
Human molecular genetics 2003;12(8):859-67.
2003: Kurt Krapfenbauer; Ephrem Engidawork; Nigel J Cairns; Michael Fountoulakis; Gert Lubec
Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders.
Brain research 2003;967(1-2):152-60.
2003: Masaki Shiozawa; Yuken Fukutani; Nobutaka Arai; Nigel J Cairns; Toshio Mizutani; Kiminori Isaki; Peter L Lantos; Yuji Wada
Glyceraldehyde 3-phosphate dehydrogenase and endothelin-1 immunoreactivity is associated with cerebral white matter damage in dentatorubral-pallidoluysian atrophy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(1):36-43.
2003: Michael Teufel; Vladimir Saudek; Jean-Pierre Ledig; Annie Bernhardt; Sylviane Boularand; Alexandra Carreau; Nigel J Cairns; Christopher Carter; David J Cowley; Danielle Duverger; Axel J Ganzhorn; Chantal Guenet; Blanche Heintzelmann; Veronique Laucher; Claude Sauvage; Tatiana Smirnova
Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase.
The Journal of biological chemistry 2003;278(8):6521-31.
2003: Susanne Greber-Platzer; Christine Fleischmann; Christa Nussbaumer; Nigel J Cairns; Gert Lubec
Increased RNA levels of the 25 kDa synaptosomal associated protein in brain samples of adult patients with Down Syndrome.
Neuroscience letters 2003;336(2):77-80.
2003: Daniela Pollak; Nigel J Cairns; Gert Lubec
Cytoskeleton derangement in brain of patients with Down syndrome, Alzheimer's disease and Pick's disease.
Journal of neural transmission. Supplementum 2003;(67):149-58.
2003: Richard A Armstrong; Nigel J Cairns
Spatial patterns of the pathological changes in the cerebellar cortex in sporadic Creutzfeldt-Jakob disease (sCJD).
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2003;41(4):183-9.
2002: Byong Chul Yoo; Kurt Krapfenbauer; Nigel J Cairns; Girma Belay; Michal Bajo; Gert Lubec
Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 2002;334(3):196-200.
2002: Richard A Armstrong; Nigel J Cairns; James W Ironside; Peter L Lantos
The spatial patterns of prion protein deposits in cases of variant Creutzfeldt-Jakob disease.
Acta neuropathologica 2002;104(6):665-9.
2002: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Spatial patterns of the vacuolation in subcortical white matter in sporadic Creutzfeldt-Jakob disease (sCJD).
Clinical neuropathology 2002;21(6):284-8.
2002: Lynnette Cook; Carol Brayne; Douglas Easton; John Grimley Evans; John H Xuereb; Nigel J Cairns; David C Rubinsztein
No evidence for an association between Saitohin Q7R polymorphism and Alzheimer's disease.
Annals of neurology 2002;52(5):690-1.
2002: Brian C Bond; David J Virley; Nigel J Cairns; A Jackie Hunter; Gary B T Moore; Stephen J Moss; Anne W Mudge; Frank S Walsh; Elena Jazin; Paul Preece
The quantification of gene expression in an animal model of brain ischaemia using TaqMan real-time RT-PCR.
Brain research. Molecular brain research 2002;106(1-2):101-16.
2002: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Are pathological lesions in neurodegenerative disorders the cause or the effect of the degeneration?
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(3):133-46.
2002: Alessandra Valerio; Marina Ferrario; Marta Paterlini; Paolo Liberini; Giuseppe Moretto; Nigel J Cairns; Marina Pizzi; PierFranco Spano
Spinal cord mGlu1a receptors: possible target for amyotrophic lateral sclerosis therapy.
Pharmacology, biochemistry, and behavior 2002;73(2):447-54.
2002: Seong Hwan Kim; Michael Fountoulakis; Nigel J Cairns; Gert Lubec
Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome.
Biochemical and biophysical research communications 2002;296(4):970-5.
2002: Lina Emilsson; Peter Saetre; Jorune Balciuniene; Anja Castensson; Nigel J Cairns; Elena Jazin
Increased monoamine oxidase messenger RNA expression levels in frontal cortex of Alzheimer's disease patients.
Neuroscience letters 2002;326(1):56-60.
2002: Clive G Ballard; Mary Johnson; Margaret A Piggott; Robert H Perry; John T O'Brien; Elise Rowan; Elaine K Perry; Peter Lantos; Nigel J Cairns; Clive Holmes
A positive association between 5HT re-uptake binding sites and depression in dementia with Lewy bodies.
Journal of affective disorders 2002;69(1-3):219-23.
2002: Peter L Lantos; Nigel J Cairns; M Nadeem Khan; Andrew King; Tamas Revesz; John C Janssen; Huw Morris; Martin N Rossor
Neuropathologic variation in frontotemporal dementia due to the intronic tau 10(+16) mutation.
Neurology 2002;58(8):1169-75.
2002: Richard A Armstrong; Nigel J Cairns; James W Ironside; Peter L Lantos
Quantification of vacuolation ("spongiform change"), surviving neurones and prion protein deposition in eleven cases of variant Creutzfeldt-Jakob disease.
Neuropathology and applied neurobiology 2002;28(2):129-35.
2002: Seong Hwan Kim; Kurt Krapfenbauer; Myeong Sook Cheon; Michael Fountoulakis; Nigel J Cairns; Gert Lubec
Human brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and increased in Pick's disease.
Neuroscience letters 2002;321(3):169-72.
2002: Richard A Armstrong; Nigel J Cairns; James W Ironside; Peter L Lantos
Laminar distribution of the pathological changes in the cerebral cortex in variant Creutzfeldt-Jakob disease (vCJD).
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2002;40(4):165-71.
2001: A Taylor; Mario Ezquerra; G Bagri; A Yip; L Goumidi; Dominique Cottel; Douglas Easton; John Grimley Evans; J Xuereb; Nigel J Cairns; Philippe Amouyel; Marie-Christine Chartier-Harlin; Carol Brayne; David C Rubinsztein
Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes.
American journal of medical genetics 2001;105(8):761-4.
2001: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
Spatial correlations between the vacuolation, prion protein deposits, and surviving neurons in the cerebral cortex in sporadic Creutzfeldt-Jakob disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(4):266-71.
2001: Jennifer A Court; Clive G Ballard; Margaret A Piggott; Mary Johnson; John T O'Brien; Clive Holmes; Nigel J Cairns; Peter Lantos; Robert H Perry; Evelyn Jaros; Elaine K Perry
Visual hallucinations are associated with lower alpha bungarotoxin binding in dementia with Lewy bodies.
Pharmacology, biochemistry, and behavior 2001;70(4):571-9.
2001: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Quantification of the vacuolation (spongiform change) and prion protein deposition in 11 patients with sporadic Creutzfeldt-Jakob disease.
Acta neuropathologica 2001;102(6):591-6.
2001: M Lambri; V Djurovic; MM Kibble; Nigel J Cairns; Safa Al-Sarraj
Specificity and sensitivity of betaAPP in head injury.
Clinical neuropathology 2001;20(6):263-71.
2001: R Vlkolinský; Nigel J Cairns; M Fountoulakis; Gert Lubec
Decreased brain levels of 2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's disease.
Neurobiology of aging 2001;22(4):547-53.
2001: Elisabeth Schuller; Talin Gulesserian; Rainer Seidl; Nigel J Cairns; G Lube
Brain t-complex polypeptide 1 (TCP- 1) related to its natural substrate beta1 tubulin is decreased in Alzheimer's disease.
Life sciences 2001;69(3):263-70.
2001: D M A Mann; A Takeuchi; S Sato; Nigel J Cairns; P L Lantos; Martin N Rossor; M Haltia; Hannu Kalimo; Takeshi Iwatsubo
Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques.
Neuropathology and applied neurobiology 2001;27(3):189-96.
2001: Rainer Seidl; Bettina Bidmon; M Bajo; P C Yoo; Nigel J Cairns; Eric C LaCasse; Gert Lubec
Evidence for apoptosis in the fetal Down syndrome brain.
Journal of child neurology 2001;16(6):438-42.
2001: Seong Hwan Kim; R Vlkolinsky; Nigel J Cairns; Michael Fountoulakis; Gert Lubec
The reduction of NADH ubiquinone oxidoreductase 24- and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease.
Life sciences 2001;68(24):2741-50.
2001: Ephrem Engidawork; Talin Gulesserian; Rainer Seidl; Nigel J Cairns; Gert Lubec
Expression of apoptosis related proteins in brains of patients with Alzheimer's disease.
Neuroscience letters 2001;303(2):79-82.
2001: Kazuhiro Ishii; Carol F Lippa; T Tomiyama; F Miyatake; K Ozawa; Akira Tamaoka; T Hasegawa; Paul E Fraser; Shin'ichi Shoji; Linda E Nee; Daniel A Pollen; P H St George-Hyslop; K Ii; T Ohtake; Rajesh N. Kalaria; Martin N Rossor; P L Lantos; Nigel J Cairns; Lindsay A Farrer; Hiroshi Mori
Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition.
Neurobiology of aging 2001;22(3):367-76.
2001: B C Yoo; Nigel J Cairns; Michael Fountoulakis; Gert Lubec
Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and Alzheimer's disease.
Dementia and geriatric cognitive disorders 2001;12(3):219-25.
2001: Byong Chul Yoo; R Vlkolinsky; Ephrem Engidawork; Nigel J Cairns; Michael Fountoulakis; Gert Lubec
Differential expression of molecular chaperones in brain of patients with Down syndrome.
Electrophoresis 2001;22(6):1233-41.
2001: A E Taylor; A Yip; Carol Brayne; Douglas Easton; John Grimley Evans; J Xuereb; Nigel J Cairns; Margaret M Esiri; David C Rubinsztein
Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease.
Journal of medical genetics 2001;38(4):232-3.
2001: Kurt Krapfenbauer; B C Yoo; Seong Hwan Kim; Nigel J Cairns; Gert Lubec
Differential display reveals downregulation of the phospholipid transfer protein (PLTP) at the mRNA level in brains of patients with Down syndrome.
Life sciences 2001;68(18):2169-79.
2001: T Murphy; A Yip; Carol Brayne; Douglas Easton; John Grimley Evans; J Xuereb; Nigel J Cairns; Margaret M Esiri; David C Rubinsztein
The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease.
Neuroreport 2001;12(3):631-4.
2001: Seong Hwan Kim; Nigel J Cairns; M Fountoulakisc; Gert Lubec
Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease.
Neuroscience letters 2001;300(1):41-4.
2001: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Spatial pattern of prion protein deposits in patients with sporadic Creutzfeldt-Jakob disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(1):19-24.
2001: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
What does the study of the spatial patterns of pathological lesions tell us about the pathogenesis of neurodegenerative disorders?
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(1):1-12.
2001: Ephrem Engidawork; Talin Gulesserian; Byong Chul Yoo; Nigel J Cairns; Gert Lubec
Alteration of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease.
Biochemical and biophysical research communications 2001;281(1):84-93.
2001: Tibor Kovács; Nigel J Cairns; Peter L Lantos
Olfactory centres in Alzheimer's disease: olfactory bulb is involved in early Braak's stages.
Neuroreport 2001;12(2):285-8.
2001: Myeong Sook Cheon; M Bajo; Talin Gulesserian; Nigel J Cairns; Gert Lubec
Evidence for the relation of herpes simplex virus type 1 to Down syndrome and Alzheimer's disease.
Electrophoresis 2001;22(3):445-8.
2001: Rainer Seidl; Nigel J Cairns; Nicolas Singewald; Stefan T Kaehler; Gert Lubec
Differences between GABA levels in Alzheimer's disease and Down syndrome with Alzheimer-like neuropathology.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(2):139-45.
2001: Richard A Armstrong; Peter L Lantos; Nigel J Cairns
The spatial patterns of prion protein deposits in Creutzfeldt-Jakob disease: comparison with beta-amyloid deposits in Alzheimer's disease.
Neuroscience letters 2001;298(1):53-6.
2001: Byong Chul Yoo; Seong Hwan Kim; Nigel J Cairns; Michael Fountoulakis; Gert Lubec
Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease.
Biochemical and biophysical research communications 2001;280(1):249-58.
2001: Nigel J Cairns
Molecular neuropathology of transgenic mouse models of Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):289-301.
2001: Myeong Sook Cheon; Michael Fountoulakis; Nigel J Cairns; Mara Dierssen; Kurt Herkner; Gert Lubec
Decreased protein levels of stathmin in adult brains with Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):281-8.
2001: Seong Hwan Kim; Angus Nairn; Nigel J Cairns; Gert Lubec
Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):263-72.
2001: Rainer Seidl; Nigel J Cairns; Gert Lubec
The brain in Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):247-61.
2001: Seong Hwan Kim; Michael Fountoulakis; Nigel J Cairns; Gert Lubec
Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):223-35.
2001: Ephrem Engidawork; Talin Gulesserian; Nadja Balic; Nigel J Cairns; Gert Lubec
Changes in nicotinic acetylcholine receptor subunits expression in brain of patients with Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):211-22.
2001: Brigitte Balcz; Lieselotte Kirchner; Nigel J Cairns; Michael Fountoulakis; Gert Lubec
Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):193-201.
2001: Ephrem Engidawork; Talin Gulesserian; Rainer Seidl; Nigel J Cairns; Gert Lubec
Expression of apoptosis related proteins: RAIDD, ZIP kinase, Bim/BOD, p21, Bax, Bcl-2 and NF-kappaB in brains of patients with Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):181-92.
2001: Talin Gulesserian; Ephrem Engidawork; Byong Chul Yoo; Nigel J Cairns; Gert Lubec
Alteration of caspases and other apoptosis regulatory proteins in Down syndrome.
Journal of neural transmission. Supplementum 2001;(61):163-79.
2001: M Bajo; B C Yoo; Nigel J Cairns; M Gratzer; Gert Lubec
Neurofilament proteins NF-L, NF-M and NF-H in brain of patients with Down syndrome and Alzheimer's disease.
Amino acids 2001;21(3):293-301.
2001: Talin Gulesserian; Rainer Seidl; R Hardmeier; Nigel J Cairns; Gert Lubec
Superoxide dismutase SOD1, encoded on chromosome 21, but not SOD2 is overexpressed in brains of patients with Down syndrome.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(1):41-6.
2001: Rainer Seidl; O Labudova; Kurt Krapfenbauer; E W Henriksson; J Craft; D Turhani-Schatzmann; T Achsel; Bettina Bidmon; Ger J M Pruijn; Nigel J Cairns; Gert Lubec
Deficient brain snRNP70K in patients with Down syndrome.
Electrophoresis 2001;22(1):43-8.
2001: Byong Chul Yoo; Michael Fountoulakis; Nigel J Cairns; Gert Lubec
Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome.
Electrophoresis 2001;22(1):172-9.
2000: Huw R Morris; Jenny R Vaughan; S R Datta; R Bandopadhyay; H A Rohan De Silva; Anette Schrag; Nigel J Cairns; David J Burn; U Nath; Peter L Lantos; Susan E Daniel; Andrew J Lees; Niall Quinn; Nicholas W Wood
Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE.
Neurology 2000;55(12):1918-20.
2000: Talin Gulesserian; Ephrem Engidawork; Nigel J Cairns; Gert Lubec
Increased protein levels of serotonin transporter in frontal cortex of patients with Down syndrome.
Neuroscience letters 2000;296(1):53-7.
2000: K Bell; Nigel J Cairns; P L Lantos; Martin N Rossor
Immunohistochemistry distinguishes: between Pick's disease and corticobasal degeneration.
Journal of neurology, neurosurgery, and psychiatry 2000;69(6):835-6.
2000: Clive G Ballard; Margaret A Piggott; Mary Johnson; Nigel J Cairns; Robert H Perry; Ian G McKeith; Evelyn Jaros; John T O'Brien; Clive Holmes; Elaine K Perry
Delusions associated with elevated muscarinic binding in dementia with Lewy bodies.
Annals of neurology 2000;48(6):868-76.
2000: Stuart Pickering-Brown; Matt Baker; Shu-Hui C. Yen; W K Liu; M Hasegawa; Nigel J Cairns; P L Lantos; Martin N Rossor; Takeshi Iwatsubo; Y Davies; David Allsop; R Furlong; F Owen; John Hardy; D M A Mann; Michael Hutton
Pick's disease is associated with mutations in the tau gene.
Annals of neurology 2000;48(6):859-67.
2000: Seong Hwan Kim; R Vlkolinsky; Nigel J Cairns; Gert Lubec
Decreased levels of complex III core protein 1 and complex V beta chain in brains from patients with Alzheimer's disease and Down syndrome.
Cellular and molecular life sciences : CMLS 2000;57(12):1810-6.
2000: Yuken Fukutani; Nigel J Cairns; Masaki Shiozawa; K Sasaki; Satoru Sudo; Kiminori Isaki; Peter L Lantos
Neuronal loss and neurofibrillary degeneration in the hippocampal cortex in late-onset sporadic Alzheimer's disease.
Psychiatry and clinical neurosciences 2000;54(5):523-9.
2000: Seong Hwan Kim; Byong Chul Yoo; J L Broers; Nigel J Cairns; Gert Lubec
Neuroendocrine-specific protein C, a marker of neuronal differentiation, is reduced in brain of patients with Down syndrome and Alzheimer's disease.
Biochemical and biophysical research communications 2000;276(1):329-34.
2000: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Clustering of Pick bodies in the dentate gyrus in Pick's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20(3):170-5.
2000: Y Narain; A Yip; T Murphy; Carol Brayne; Douglas Easton; John Grimley Evans; J Xuereb; Nigel J Cairns; Margaret M Esiri; Robert A Furlong; David C Rubinsztein
The ACE gene and Alzheimer's disease susceptibility.
Journal of medical genetics 2000;37(9):695-7.
2000: Masaki Shiozawa; Yuken Fukutani; K Sasaki; Kiminori Isaki; T Hamano; M Hirayama; K Imamura; M Mukai; Nobutaka Arai; Nigel J Cairns
Corticobasal degeneration: an autopsy case clinically diagnosed as progressive supranuclear palsy.
Clinical neuropathology 2000;19(4):192-9.
2000: Richard A Armstrong; Nigel J Cairns; P L Lantos
Beta-amyloid deposition in the temporal lobe of patients with dementia with Lewy bodies: comparison with non-demented cases and Alzheimer's disease.
Dementia and geriatric cognitive disorders 2000;11(4):187-92.
2000: Gunter P Eckert; Nigel J Cairns; Athanasios Maras; Wagner F Gattaz; Walter E Müller
Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease.
Dementia and geriatric cognitive disorders 2000;11(4):181-6.
2000: Stuart Pickering-Brown; F Owen; A Isaacs; Julie Snowden; Anoop Varma; David Neary; R Furlong; Susan E Daniel; Nigel J Cairns; D M A Mann
Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pick- or microvacuolar-type histology.
Experimental neurology 2000;163(2):452-6.
2000: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
A quantitative study of the pathological lesions in the neocortex and hippocampus of twelve patients with corticobasal degeneration.
Experimental neurology 2000;163(2):348-56.
2000: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
The spatial pattern of the vacuolation in patients with sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 2000;281(2-3):187-90.
2000: Sharon L Eastwood; Nigel J Cairns; Paul J Harrison
Synaptophysin gene expression in schizophrenia. Investigation of synaptic pathology in the cerebral cortex.
The British journal of psychiatry : the journal of mental science 2000;176():236-42.
1999: Tibor Kovács; Nigel J Cairns; Peter L Lantos
beta-amyloid deposition and neurofibrillary tangle formation in the olfactory bulb in ageing and Alzheimer's disease.
Neuropathology and applied neurobiology 1999;25(6):481-91.
1999: K Karlsson; Nigel J Cairns; Gert Lubec; Michael Fountoulakis
Enrichment of human brain proteins by heparin chromatography.
Electrophoresis 1999;20(14):2970-6.
1999: Jennifer A Court; DP Spurden; S Lloyd; Ian G McKeith; Clive G Ballard; Nigel J Cairns; R Kerwin; Robert H Perry; Elaine K Perry
Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus.
Journal of neurochemistry 1999;73(4):1590-7.
1999: Tibor Kovács; Nigel J Cairns; Peter L Lantos
Alpha-2-macroglobulin intronic polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease.
Neuroscience letters 1999;273(1):61-83.
1999: T Gómez-Isla; Whitfield B Growdon; MJ McNamara; David Nochlin; Thomas D Bird; JC Arango; Francisco Lopera; Kenneth S Kosik; P L Lantos; Nigel J Cairns; Bradley T Hyman
The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors.
Brain : a journal of neurology 1999;122 ( Pt 9)():1709-19.
1999: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Laminar distribution of pick bodies, pick cells and Alzheimer disease pathology in the frontal and temporal cortex in Pick's disease.
Neuropathology and applied neurobiology 1999;25(4):266-71.
1999: Z Guan; Y Wang; Nigel J Cairns; P L Lantos; Gustav Dallner; Pavel Sindelar
Decrease and structural modifications of phosphatidylethanolamine plasmalogen in the brain with Alzheimer disease.
Journal of neuropathology and experimental neurology 1999;58(7):740-7.
1999: Clive G Ballard; Clive Holmes; Ian G McKeith; D Neill; John T O'Brien; Nigel J Cairns; Peter Lantos; Elaine K Perry; Paul Ince; Robert H Perry
Psychiatric morbidity in dementia with Lewy bodies: a prospective clinical and neuropathological comparative study with Alzheimer's disease.
The American journal of psychiatry 1999;156(7):1039-45.
1999: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Clustering of cerebral cortical lesions in patients with corticobasal degeneration.
Neuroscience letters 1999;268(1):5-8.
1999: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Quantification of pathological lesions in the frontal and temporal lobe of ten patients diagnosed with Pick's disease.
Acta neuropathologica 1999;97(5):456-62.
1999: D J Dow; N Lindsey; Nigel J Cairns; Carol Brayne; D Robinson; F A Huppert; E S Paykel; J Xuereb; Gordon K Wilcock; J L Whittaker; David C Rubinsztein
Alpha-2 macroglobulin polymorphism and Alzheimer disease risk in the UK.
Nature genetics 1999;22(1):16-7; author reply 21-2.
1999: S Greber; Gert Lubec; Nigel J Cairns; Michael Fountoulakis
Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down syndrome and Alzheimer's disease.
Electrophoresis 1999;20(4-5):928-34.
1999: Hanno Langen; Peter Berndt; Daniel Röder; Nigel J Cairns; Gert Lubec; Michael Fountoulakis
Two-dimensional map of human brain proteins.
Electrophoresis 1999;20(4-5):907-16.
1999: O Labudova; Erwin Kitzmueller; H Rink; Nigel J Cairns; Gert Lubec
Increased phosphoglycerate kinase in the brains of patients with Down's syndrome but not with Alzheimer's disease.
Clinical science (London, England : 1979) 1999;96(3):279-85.
1999: Yuken Fukutani; Nigel J Cairns; I P Everall; A Chadwick; Kiminori Isaki; Peter L Lantos
Cerebellar dentate nucleus in Alzheimer's disease with myoclonus.
Dementia and geriatric cognitive disorders 1999;10(2):81-8.
1999: Gert Lubec; O Labudova; Nigel J Cairns; Michael Fountoulakis
Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down's syndrome.
Neuroscience letters 1999;260(2):141-5.
1999: Rainer Seidl; Susanne Fang-Kircher; Bettina Bidmon; Nigel J Cairns; Gert Lubec
Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome.
Neuroscience letters 1999;260(1):9-12.
1999: R Armstrong; Nigel J Cairns; P Lantos
The spatial patterns of Pick bodies, Pick cells and Alzheimer's disease pathology in Pick's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 1999;19(1):64-70.
1999: Gunter P Eckert; Nigel J Cairns; Walter E Müller
Piracetam reverses hippocampal membrane alterations in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1999;106(7-8):757-61.
1999: D Schatzmann-Turhani; O Labudova; Kristina Yeghiazaryan; H Rink; Erwin Hauser; Nigel J Cairns; Gert Lubec
Overexpression of DNAse I in brain of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():353-62.
1999: Michael Fountoulakis; Nigel J Cairns; Gert Lubec
Increased levels of 14-3-3 gamma and epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome.
Journal of neural transmission. Supplementum 1999;57():323-35.
1999: Byong Chul Yoo; Rainer Seidl; Nigel J Cairns; Gert Lubec
Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 1999;57():315-22.
1999: Kristina Yeghiazaryan; D Turhani-Schatzmann; O Labudova; Elisabeth Schuller; E N Olson; Nigel J Cairns; Gert Lubec
Downregulation of the transcription factor scleraxis in brain of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():305-14.
1999: Rainer Seidl; M Bajo; K Böhm; Eric C LaCasse; Alex E MacKenzie; Nigel J Cairns; Gert Lubec
Neuronal apoptosis inhibitory protein (NAIP)-like immunoreactivity in brains of adult patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():283-91.
1999: Susanne Greber-Platzer; D Schatzmann-Turhani; Nigel J Cairns; Brigitte Balcz; Gert Lubec
Expression of the transcription factor ETS2 in brain of patients with Down syndrome--evidence against the overexpression-gene dosage hypothesis.
Journal of neural transmission. Supplementum 1999;57():269-81.
1999: O Labudova; Nigel J Cairns; Erwin Kitzmüller; Gert Lubec
Impaired brain glucose metabolism in patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():247-56.
1999: Rainer Seidl; Stefan T Kaehler; Helmut Prast; Nicolas Singewald; Nigel J Cairns; M Gratzer; Gert Lubec
Serotonin (5-HT) in brains of adult patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():221-32.
1999: Kurt Krapfenbauer; Byong Chul Yoo; Nigel J Cairns; Gert Lubec
Differential display reveals deteriorated mRNA levels of NADH3 (complex I) in cerebellum of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():211-20.
1999: Gert Lubec; M Nonaka; Kurt Krapfenbauer; M Gratzer; Nigel J Cairns; Michael Fountoulakis
Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level.
Journal of neural transmission. Supplementum 1999;57():161-77.
1999: O Labudova; Erwin Kitzmueller; H Rink; Nigel J Cairns; Gert Lubec
Gene expression in fetal Down syndrome brain as revealed by subtractive hybridization.
Journal of neural transmission. Supplementum 1999;57():125-36.
1999: Erwin Kitzmueller; O Labudova; H Rink; Nigel J Cairns; Gert Lubec
Altered gene expression in fetal Down syndrome brain as revealed by the gene hunting technique of subtractive hybridization.
Journal of neural transmission. Supplementum 1999;57():99-124.
1999: Susanne Greber-Platzer; Brigitte Balcz; Nigel J Cairns; Gert Lubec
c-fos expression in brains of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():75-85.
1999: Nigel J Cairns
Neuropathology.
Journal of neural transmission. Supplementum 1999;57():61-74.
1999: Gert Lubec; O Labudova; Nigel J Cairns; Peter Berndt; H Langen; Michael Fountoulakis
Reduced aldehyde dehydrogenase levels in the brain of patients with Down syndrome.
Journal of neural transmission. Supplementum 1999;57():21-40.
1999: Susanne Fang-Kircher; O Labudova; Erwin Kitzmueller; H Rink; Nigel J Cairns; Gert Lubec
Increased steady state mRNA levels of DNA-repair genes XRCC1, ERCC2 and ERCC3 in brain of patients with Down syndrome.
Life sciences 1999;64(18):1689-99.
1999: Clive Holmes; Nigel J Cairns; Peter Lantos; A Mann
Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies.
The British journal of psychiatry : the journal of mental science 1999;174():45-50.
1999: O Labudova; Nigel J Cairns; Thomas Koeck; Erwin Kitzmueller; H Rink; Gert Lubec
Thyroid stimulating hormone-receptor overexpression in brain of patients with Down syndrome and Alzheimer's disease.
Life sciences 1999;64(12):1037-44.
1999: D Schatzmann-Turhani; Susanne Greber-Platzer; Nigel J Cairns; Gert Lubec
Determination of the protooncogene ets-2 gene transcript in human brain at the atto-gram-level by the use of competitive RT/PCR.
Amino acids 1999;16(1):13-9.
1999: Pat Kehoe; C Russ; S McIlory; H Williams; Peter Holmans; C Holmes; D Liolitsa; D Vahidassr; J Powell; B McGleenon; M Liddell; Robert Plomin; Kevin B Dynan; N Williams; Jim Neal; Nigel J Cairns; Gordon K Wilcock; Peter Passmore; Simon Lovestone; Julie Williams; Michael J Owen
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
Nature genetics 1999;21(1):71-2.
1998: Richard A Armstrong; Nigel J Cairns; P L Lantos
Spatial distribution of diffuse, primitive, and classic amyloid-beta deposits and blood vessels in the upper laminae of the frontal cortex in Alzheimer disease.
Alzheimer disease and associated disorders 1998;12(4):378-83.
1998: Pat Kehoe; Hywel Williams; Peter Holmans; Gordon K Wilcock; Nigel J Cairns; Jim Neal; Michael J Owen
The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.
Journal of medical genetics 1998;35(12):1034-5.
1998: Carol F Lippa; H Fujiwara; D M A Mann; Benoit I Giasson; M Baba; ML Schmidt; Linda E Nee; B O'Connell; Daniel A Pollen; Peter St George-Hyslop; Bernardino Ghetti; David Nochlin; Thomas D Bird; Nigel J Cairns; Virginia M-Y Lee; Takeshi Iwatsubo; John Q Trojanowski
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes.
The American journal of pathology 1998;153(5):1365-70.
1998: O Labudova; Susanne Fang-Kircher; Nigel J Cairns; Heike Moenkemann; Kristina Yeghiazaryan; Gert Lubec
Brain vasopressin levels in Down syndrome and Alzheimer's disease.
Brain research 1998;806(1):55-9.
1998: O Labudova; Kurt Krapfenbauer; Heike Moenkemann; H Rink; Erwin Kitzmüller; Nigel J Cairns; Gert Lubec
Decreased transcription factor junD in brains of patients with Down syndrome.
Neuroscience letters 1998;252(3):159-62.
1998: Maria Grazia Spillantini; R Anthony Crowther; Ross Jakes; Nigel J Cairns; P L Lantos; Michel Goedert
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
Neuroscience letters 1998;251(3):205-8.
1998: Michael Hermon; Nigel J Cairns; J M Egly; A Fery; O Labudova; Gert Lubec
Expression of DNA excision-repair-cross-complementing proteins p80 and p89 in brain of patients with Down Syndrome and Alzheimer's disease.
Neuroscience letters 1998;251(1):45-8.
1998: Walter E Müller; Gunter P Eckert; K Scheuer; Nigel J Cairns; Athanasios Maras; Wagner F Gattaz
Effects of beta-amyloid peptides on the fluidity of membranes from frontal and parietal lobes of human brain. High potencies of A beta 1-42 and A beta 1-43.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(1):10-5.
1998: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
The spatial patterns of Lewy bodies, senile plaques, and neurofibrillary tangles in dementia with Lewy bodies.
Experimental neurology 1998;150(1):122-7.
1998: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Clustering of Pick bodies in patients with Pick's disease.
Neuroscience letters 1998;242(2):81-4.
1998: C Tysoe; J Whittaker; John H Xuereb; Nigel J Cairns; Marc Cruts; Christine Van Broeckhoven; Gordon K Wilcock; David C Rubinsztein
A presenilin-1 truncating mutation is present in two cases with autopsy-confirmed early-onset Alzheimer disease.
American journal of human genetics 1998;62(1):70-6.
1997: Payam Rezaie; Nigel J Cairns; David Male
Expression of adhesion molecules on human fetal cerebral vessels: relationship to microglial colonisation during development.
Brain research. Developmental brain research 1997;104(1-2):175-89.
1997: K A Marshall; Susan E Daniel; Nigel J Cairns; Peter Jenner; Barry Halliwell
Upregulation of the anti-apoptotic protein Bcl-2 may be an early event in neurodegeneration: studies on Parkinson's and incidental Lewy body disease.
Biochemical and biophysical research communications 1997;240(1):84-7.
1997: Rainer Seidl; S Greber; Elisabeth Schuller; Günter Bernert; Nigel J Cairns; Gert Lubec
Evidence against increased oxidative DNA-damage in Down syndrome.
Neuroscience letters 1997;235(3):137-40.
1997: AL Jones; Fiona Middle; Carol Guy; Gillian Spurlock; Nigel J Cairns; Peter McGuffin; Nick Craddock; Michael J Owen; Michael C O'Donovan
No evidence for expanded polyglutamine sequences in bipolar disorder and schizophrenia.
Molecular psychiatry 1997;2(6):478-82.
1997: Z I Alam; A Jenner; Susan E Daniel; Andrew J Lees; Nigel J Cairns; CD Marsden; Peter Jenner; Barry Halliwell
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.
Journal of neurochemistry 1997;69(3):1196-203.
1997: Rainer Seidl; Elisabeth Schuller; Nigel J Cairns; Gert Lubec
Evidence against increased glycoxidation in patients with Alzheimer's disease.
Neuroscience letters 1997;232(1):49-52.
1997: Akira Sawa; Fumitaka Oyama; Nigel J Cairns; Naoji Amano; M Matsushita
Aberrant expression of bcl-2 gene family in Down's syndrome brains.
Brain research. Molecular brain research 1997;48(1):53-9.
1997: Yuken Fukutani; K Sasaki; M Mukai; R Matsubara; Kiminori Isaki; Nigel J Cairns
Neurons and extracellular neurofibrillary tangles in the hippocampal subdivisions in early-onset familial Alzheimer's disease: a case study.
Psychiatry and clinical neurosciences 1997;51(4):227-31.
1997: Yuken Fukutani; Nigel J Cairns; Martin N Rossor; Peter L Lantos
Cerebellar pathology in sporadic and familial Alzheimer's disease including APP 717 (Val-->Ile) mutation cases: a morphometric investigation.
Journal of the neurological sciences 1997;149(2):177-84.
1997: RM Duberley; Ian P Johnson; Praveen Anand; P N Leigh; Nigel J Cairns
Immunocytochemical studies of neurotrophins in cerebral motor cortex in Amyotrophic Lateral Sclerosis.
Brain research 1997;763(2):259-63.
1997: Nigel J Cairns; P F Atkinson; Diane P Hanger; Brian H Anderton; Susan E Daniel; Peter L Lantos
Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease.
Neuroscience letters 1997;230(1):49-52.
1997: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
beta-Amyloid (A beta) deposition in the medial temporal lobe of patients with dementia with Lewy bodies.
Neuroscience letters 1997;227(3):193-6.
1997: RM Duberley; Ian P Johnson; Praveen Anand; P N Leigh; Nigel J Cairns
Neurotrophin-3-like immunoreactivity and Trk C expression in human spinal motoneurones in amyotrophic lateral sclerosis.
Journal of the neurological sciences 1997;148(1):33-40.
1997: L Lyras; Nigel J Cairns; A Jenner; Peter Jenner; Barry Halliwell
An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease.
Journal of neurochemistry 1997;68(5):2061-9.
1997: Richard A Armstrong; Nigel J Cairns; Peter L Lantos
Dementia with Lewy bodies: clustering of Lewy bodies in human patients.
Neuroscience letters 1997;224(1):41-4.
1997: C Schneider; Daniele Risser; Lieselotte Kirchner; Erwin Kitzmüller; Nigel J Cairns; Helmut Prast; Nicolas Singewald; Gert Lubec
Similar deficits of central histaminergic system in patients with Down syndrome and Alzheimer disease.
Neuroscience letters 1997;222(3):183-6.
1997: C Tysoe; J Whittaker; Nigel J Cairns; P F Atkinson; C R Harrington; John H Xuereb; Gordon K Wilcock; David C Rubinsztein
Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease.
Neuroscience letters 1997;222(1):68-9.
1997: Nigel J Cairns; P F Atkinson; Tibor Kovács; Andrew J Lees; Susan E Daniel; Peter L Lantos
Apolipoprotein E e4 allele frequency in patients with multiple system atrophy.
Neuroscience letters 1997;221(2-3):161-4.
1997: Daniele Risser; Gert Lubec; Nigel J Cairns; Mario Herrera-Marschitz
Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome.
Life sciences 1997;60(15):1231-7.
1996: Nigel J Cairns; P L Lantos
Brain tissue banks in psychiatric and neurological research.
Journal of clinical pathology 1996;49(11):870-3.
1996: Günter Bernert; Maria Nemethova; Mario Herrera-Marschitz; Nigel J Cairns; Gert Lubec
Decreased cyclin dependent kinase in brain of patients with Down syndrome.
Neuroscience letters 1996;216(1):68-70.
1996: Yuken Fukutani; Nigel J Cairns; Martin N Rossor; P L Lantos
Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease.
Neuroscience letters 1996;214(1):33-6.
1996: D M A Mann; Takeshi Iwatsubo; Nigel J Cairns; P L Lantos; David Nochlin; Shuzo M Sumi; Thomas D Bird; Parvoneh Poorkaj-Navas; John Hardy; Michael Hutton; Guy Prihar; Richard Crook; Martin N Rossor; Matti Haltia
Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43).
Annals of neurology 1996;40(2):149-56.
1996: Payam Rezaie; Nigel J Cairns; A Chadwick; P L Lantos
Lewy bodies are located preferentially in limbic areas in diffuse Lewy body disease.
Neuroscience letters 1996;212(2):111-4.
1996: K Scheuer; A Maras; Wagner F Gattaz; Nigel J Cairns; hans förstl; W E Müller
Cortical NMDA receptor properties and membrane fluidity are altered in Alzheimer's disease.
Dementia (Basel, Switzerland) 1996;7(4):210-4.
1996: Peter Muir; F Nicholson; G T Spencer; J F Ajetunmobi; W G Starkey; M Khan; L C Archard; Nigel J Cairns; V E Anderson; P N Leigh; R S Howard; Jangu Banatvala
Enterovirus infection of the central nervous system of humans: lack of association with chronic neurological disease.
The Journal of general virology 1996;77 ( Pt 7)():1469-76.
1996: Richard A Armstrong; Nigel J Cairns; R Patel; Peter L Lantos; Martin N Rossor
Relationships between beta-amyloid (A beta) deposits and blood vessels in patients with sporadic and familial Alzheimer's disease.
Neuroscience letters 1996;207(3):171-4.
1996: D M A Mann; Takeshi Iwatsubo; Yasuo Ihara; Nigel J Cairns; P L Lantos; Nenad Bogdanovic; Lars Lannfelt; Bengt Winblad; M L Maat-Schieman; Martin N Rossor
Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene.
The American journal of pathology 1996;148(4):1257-66.
1996: Rashida Anwar; TP Moynihan; Helen C Ardley; N Brindle; P Louise Coletta; Nigel J Cairns; Alexander F Markham; Philip A Robinson
Molecular analysis of the presenilin 1 (S182) gene in "sporadic" cases of Alzheimer's disease: identification and characterisation of unusual splice variants.
Journal of neurochemistry 1996;66(4):1774-7.
1996: Rainer Seidl; Simone Beninati; Nigel J Cairns; Nicolas Singewald; Daniele Risser; H Bavan; Maria Nemethova; Gert Lubec
Polyamines in frontal cortex of patients with Down syndrome and Alzheimer disease.
Neuroscience letters 1996;206(2-3):193-5.
1996: Richard A Armstrong; Nigel J Cairns; D Myers; C U M Smith; P L Lantos; Martin N Rossor
A comparison of beta-amyloid deposition in the medial temporal lobe in sporadic Alzheimer's disease, Down's syndrome and normal elderly brains.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1996;5(1):35-41.
1996: Daniele Risser; Z B You; Nigel J Cairns; Mario Herrera-Marschitz; Rainer Seidl; C Schneider; L Terenius; Gert Lubec
Endogenous opioids in frontal cortex of patients with Down syndrome.
Neuroscience letters 1996;203(2):111-4.
1996: Wagner F Gattaz; R Levy; Nigel J Cairns; hans förstl; Dieter F Braus; A Maras
[Relevance of metabolism of membrane phospholipids for Alzheimer dementia].
Fortschritte der Neurologie-Psychiatrie 1996;64(1):8-12.
1996: Marianne Hayn; K Kremser; Nicolas Singewald; Nigel J Cairns; Maria Nemethova; Barbara Lubec; Gert Lubec
Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in Down's syndrome and Alzheimer's disease.
Life sciences 1996;59(7):537-44.
1996: Wagner F Gattaz; Nigel J Cairns; R Levy; hans förstl; Dieter F Braus; A Maras
Decreased phospholipase A2 activity in the brain and in platelets of patients with Alzheimer's disease.
European archives of psychiatry and clinical neuroscience 1996;246(3):129-31.
1996: Halina BARAN; Nigel J Cairns; Barbara Lubec; Gert Lubec
Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome.
Life sciences 1996;58(21):1891-9.
1995: Yuken Fukutani; K Kobayashi; I Nakamura; K Watanabe; Kiminori Isaki; Nigel J Cairns
Neurons, intracellular and extracellular neurofibrillary tangles in subdivisions of the hippocampal cortex in normal ageing and Alzheimer's disease.
Neuroscience letters 1995;200(1):57-60.
1995: Peter Muir; F Nicholson; M K Sharief; E J Thompson; Nigel J Cairns; P Lantos; G T Spencer; Henry Kaminski; Jangu Banatvala
Evidence for persistent enterovirus infection of the central nervous system in patients with previous paralytic poliomyelitis.
Annals of the New York Academy of Sciences 1995;753():219-32.
1995: V E Anderson; Nigel J Cairns; P N Leigh
Involvement of the amygdala, dentate and hippocampus in motor neuron disease.
Journal of the neurological sciences 1995;129 Suppl():75-8.
1995: Ann E Kingsbury; Oliver J F Foster; A P Nisbet; Nigel J Cairns; L Bray; David Eve; Andrew J Lees; CD Marsden
Tissue pH as an indicator of mRNA preservation in human post-mortem brain.
Brain research. Molecular brain research 1995;28(2):311-8.
1995: Wagner F Gattaz; A Maras; Nigel J Cairns; R Levy; hans förstl
Decreased phospholipase A2 activity in Alzheimer brains.
Biological psychiatry 1995;37(1):13-7.
1994: hans förstl; Alistair Burns; R Levy; Nigel J Cairns
Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1994;165(2):53-9.
1994: Fumitaka Oyama; Nigel J Cairns; H Shimada; R Oyama; K Titani; Yasuo Ihara
Down's syndrome: up-regulation of beta-amyloid protein precursor and tau mRNAs and their defective coordination.
Journal of neurochemistry 1994;62(3):1062-6.
1994: hans förstl; R Levy; Alistair Burns; P Luthert; Nigel J Cairns
Disproportionate loss of noradrenergic and cholinergic neurons as cause of depression in Alzheimer's disease--a hypothesis.
Pharmacopsychiatry 1994;27(1):11-5.
1993: hans förstl; Alistair Burns; R Levy; Nigel J Cairns; P Luthert; P Lantos
Neuropathological correlates of behavioural disturbance in confirmed Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1993;163():364-8.
1993: hans förstl; Alistair Burns; R Levy; Nigel J Cairns
Neuropathological basis for drawing disability (constructional apraxia) in Alzheimer's disease.
Psychological medicine 1993;23(3):623-9.
1993: hans förstl; Alistair Burns; P Luthert; Nigel J Cairns; R Levy
The Lewy-body variant of Alzheimer's disease. Clinical and pathological findings.
The British journal of psychiatry : the journal of mental science 1993;162():385-92.
1993: F Y Ghauri; Jeremy K Nicholson; B C Sweatman; J Wood; C R Beddell; John C Lindon; Nigel J Cairns
NMR spectroscopy of human post mortem cerebrospinal fluid: distinction of Alzheimer's disease from control using pattern recognition and statistics.
NMR in biomedicine 1993;6(2):163-7.
1993: Nigel J Cairns; A Chadwick; P L Lantos; R Levy; Martin N Rossor
Beta A4 protein deposition in familial Alzheimer's disease with the mutation in codon 717 of the beta A4 amyloid precursor protein gene and sporadic Alzheimer's disease.
Neuroscience letters 1993;149(2):137-40.
1992: hans förstl; Alistair Burns; P Luthert; Nigel J Cairns; P Lantos; R Levy
Clinical and neuropathological correlates of depression in Alzheimer's disease.
Psychological medicine 1992;22(4):877-84.
1992: Nigel J Cairns; A Chadwick; P J Luthert; P L Lantos
Astrocytosis, beta A4-protein deposition and paired helical filament formation in Alzheimer's disease.
Journal of the neurological sciences 1992;112(1-2):68-75.
1992: hans förstl; Alistair Burns; R Levy; Nigel J Cairns; P Luthert; P Lantos
Neurologic signs in Alzheimer's disease. Results of a prospective clinical and neuropathologic study.
Archives of neurology 1992;49(10):1038-42.
1992: hans förstl; Alistair Burns; Nigel J Cairns; P Luthert; P Lantos; R Levy
[Organic correlates of depressive symptoms in Alzheimer's dementia. Results of a prospective study, review of the literature].
Der Nervenarzt 1992;63(9):566-74.
1992: Michel Goedert; Maria Grazia Spillantini; Nigel J Cairns; R Anthony Crowther
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms.
Neuron 1992;8(1):159-68.
1991: Nigel J Cairns; A Chadwick; P J Luthert; P L Lantos
beta-Amyloid protein load is relatively uniform throughout neocortex and hippocampus in elderly Alzheimer's disease patients.
Neuroscience letters 1991;129(1):115-8.
1991: hans förstl; Nigel J Cairns; Alistair Burns; P Luthert
Medical disorders in Alzheimer's disease and vascular dementia.
Postgraduate medical journal 1991;67(790):742-4.
1991: Diane P Hanger; Jean-Pierre Brion; J M Gallo; Nigel J Cairns; P J Luthert; Brian H Anderton
Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated.
The Biochemical journal 1991;275 ( Pt 1)():99-104.
1991: hans förstl; Alistair Burns; P Luthert; Nigel J Cairns
[Dementia and internal diseases: incidence of internal diseases in Alzheimer dementia, vascular dementia and other dementing diseases].
Zeitschrift für Gerontologie 1991;24(2):91-3.
1991: Richard A Armstrong; D Myers; C U M Smith; Nigel J Cairns; P J Luthert
Alzheimer's disease: the relationship between the density of senile plaques, neurofibrillary tangles and A4 protein in human patients.
Neuroscience letters 1991;123(2):141-3.
1988: Nigel J Cairns; Susan Wonnacott
[3H](-)nicotine binding sites in fetal human brain.
Brain research 1988;475(1):1-7.