FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Brad Buckman

Research Profile

Chemicals & Drugs

Living Beings

Concepts & Ideas

Procedures

Genes & Molecular Sequences

Molecular Structure

Co-author Network

Publications

TOP 3
Marc Adler; Brad Buckman; Judi Bryant; Zheng Chang; Kieu Chu; Kumar Emayan; Paul Hrvatin; Imadul Islam; John Morser; Drew Sukovich; Christopher West; Shendong Yuan; Marc Whitlow
Structures of potent selective peptide mimetics bound to carboxypeptidase B.
Judi Bryant; Joseph M Post; Serene Alexander; Yi-Xin Wang; Lorraine Kent; Sabine Schirm; Jih-Lie Tseng; Babu Subramanyam; Brad Buckman; Imadul Islam; Shendong Yuan; Mark E Sullivan; Mike Snider; John Morser
Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (I): in vitro effects on platelets.
Yi-Xin Wang; Jon Vincelette; Valdeci da Cunha; Baby Martin-McNulty; Cornell Mallari; Richard M Fitch; Serene Alexander; Imadul Islam; Brad Buckman; Shendong Yuan; Joseph M Post; Babu Subramanyam; Ronald Vergona; Mark E Sullivan; William P Dole; John Morser; Judi Bryant
A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Brad Buckman (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2008: Marc Adler; Brad Buckman; Judi Bryant; Zheng Chang; Kieu Chu; Kumar Emayan; Paul Hrvatin; Imadul Islam; John Morser; Drew Sukovich; Christopher West; Shendong Yuan; Marc Whitlow
Structures of potent selective peptide mimetics bound to carboxypeptidase B.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 2):149-57.
2008: Judi Bryant; Joseph M Post; Serene Alexander; Yi-Xin Wang; Lorraine Kent; Sabine Schirm; Jih-Lie Tseng; Babu Subramanyam; Brad Buckman; Imadul Islam; Shendong Yuan; Mark E Sullivan; Mike Snider; John Morser
Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (I): in vitro effects on platelets.
Thrombosis research 2008;122(4):523-32.
2007: Yi-Xin Wang; Jon Vincelette; Valdeci da Cunha; Baby Martin-McNulty; Cornell Mallari; Richard M Fitch; Serene Alexander; Imadul Islam; Brad Buckman; Shendong Yuan; Joseph M Post; Babu Subramanyam; Ronald Vergona; Mark E Sullivan; William P Dole; John Morser; Judi Bryant
A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models.
Thrombosis and haemostasis 2007;97(5):847-55.
2007: Imadul Islam; Judi Bryant; Karen May; Raju Mohan; Shendong Yuan; Lorraine Kent; John Morser; Lei Zhao; Ronald Vergona; Kathy White; Marc Adler; Marc Whitlow; Brad Buckman
3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa).
Bioorganic & medicinal chemistry letters 2007;17(5):1349-54.
2007: Yi-Xin Wang; Valdeci da Cunha; Jon Vincelette; Lei Zhao; Mariko Nagashima; Kohichi Kawai; Shendong Yuan; Kumar Emayan; Imadul Islam; Junko Hosoya; Mark E Sullivan; William P Dole; John Morser; Brad Buckman; Ronald Vergona
A novel inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa) - part II: enhancement of both exogenous and endogenous fibrinolysis in animal models of thrombosis.
Thrombosis and haemostasis 2007;97(1):54-61.
2007: Yi-Xin Wang; Lei Zhao; Mariko Nagashima; Jon Vincelette; Drew Sukovich; Weiwei Li; Babu Subramanyam; Shendong Yuan; Kumar Emayan; Imadul Islam; Paul Hrvatin; Judi Bryant; David R Light; Ronald Vergona; John Morser; Brad Buckman
A novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) - part I: pharmacological characterization.
Thrombosis and haemostasis 2007;97(1):45-53.
2005: Marc Adler; Judi Bryant; Brad Buckman; Imadul Islam; Brent Larsen; Silke Finster; Lorraine Kent; Karen May; Raju Mohan; Shendong Yuan; Marc Whitlow
Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase B.
Biochemistry 2005;44(26):9339-47.
2005: Richard I Feldman; James M Wu; Mark A Polokoff; Monica J Kochanny; Harald Dinter; Daguang Zhu; Sandra L Biroc; Bruno Alicke; Judi Bryant; Shendong Yuan; Brad Buckman; Dao Lentz; Mike Ferrer; Marc Whitlow; Marc Adler; Silke Finster; Zheng Chang; Damian O Arnaiz
Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.
The Journal of biological chemistry 2005;280(20):19867-74.
2005: Brad Buckman; Yuo-Ling Chou; Margaret A McCarrick; Amy Liang; Dao Lentz; Raju Mohan; Michael M Morrissey; Kenneth J Shaw; Lan Trinh; David R Light
Solid-phase synthesis of naphthylamidines as factor VIIa/tissue factor inhibitors.
Bioorganic & medicinal chemistry letters 2005;15(9):2249-52.
2003: Bin Ye; Shawn Bauer; Brad Buckman; Ameen Ghannam; Brian D Griedel; Seock-Kyu Khim; Wheeseong Lee; Karna L Sacchi; Kenneth J Shaw; Amy Liang; Qingyu Wu; Zuchun Zhao
Synthesis and biological evaluation of menthol-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Bioorganic & medicinal chemistry letters 2003;13(19):3361-5.
2003: Lei Zhao; Brad Buckman; Marian Seto; John Morser; Mariko Nagashima
Mutations in the substrate binding site of thrombin-activatable fibrinolysis inhibitor (TAFI) alter its substrate specificity.
The Journal of biological chemistry 2003;278(34):32359-66.
2002: Gary Phillips; William J Guilford; Brad Buckman; David D Davey; Keith Eagen; Sunil Koovakkat; Amy Liang; Margaret A McCarrick; Raju Mohan; Howard P Ng; Michael Pinkerton; Babu Subramanyam; Elena Ho; Lan Trinh; Marc Whitlow; Shung Wu; Wei Xu; Michael M Morrissey
Design, synthesis, and activity of a novel series of factor Xa inhibitors: optimization of arylamidine groups.
Journal of medicinal chemistry 2002;45(12):2484-93.
2002: Brad Buckman; Ameen Ghannam; Li Angela; Meina Liang; Raju Mohan; Howard P Ng
Automated parallel solid-phase synthesis of non-peptide CCR1 receptor antagonists.
Combinatorial chemistry & high throughput screening 2002;5(3):249-51.
2002: Howard P Ng; Brad Buckman; Keith Eagen; William J Guilford; Monica J Kochanny; Raju Mohan; Kenneth J Shaw; Shung C Wu; Dao Lentz; Amy Liang; Lan Trinh; Elena Ho; David Smith; Babu Subramanyam; Ronald Vergona; Janette Walters; Kathy A White; Mark E Sullivan; Michael M Morrissey; Gary B Phillips
Design, synthesis, and biological activity of novel factor Xa inhibitors: 4-aryloxy substituents of 2,6-diphenoxypyridines.
Bioorganic & medicinal chemistry 2002;10(3):657-66.
2001: Richard Horuk; S Shurey; Howard P Ng; K May; John G Bauman; Imadul Islam; Ameen Ghannam; Brad Buckman; Guo-Ping Wei; Wei Xu; Meina Liang; Mary Rosser; Laura Dunning; Joseph Hesselgesser; RM Snider; Michael M Morrissey; H Daniel Perez; C Green
CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model.
Immunology letters 2001;76(3):193-201.
2001: Richard Horuk; C Clayberger; Alan Krensky; Z Wang; H J Grone; C Weber; Kim S C Weber; Peter J Nelson; K May; Mary Rosser; Laura Dunning; Meina Liang; Brad Buckman; Ameen Ghannam; Howard P Ng; Imadul Islam; John G Bauman; Guo-Ping Wei; S Monahan; Wei Xu; RM Snider; Michael M Morrissey; Joseph Hesselgesser; H Daniel Perez
A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection.
The Journal of biological chemistry 2001;276(6):4199-204.
2000: Meina Liang; Cornell Mallari; Mary Rosser; Howard P Ng; K May; S Monahan; John G Bauman; Imadul Islam; Ameen Ghannam; Brad Buckman; K Shaw; Guo-Ping Wei; Wei Xu; Z Zhao; E Ho; J Shen; H Oanh; Babu Subramanyam; Ronald Vergona; D Taub; Laura Dunning; S Harvey; RM Snider; Joseph Hesselgesser; Michael M Morrissey; H Daniel Perez
Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1.
The Journal of biological chemistry 2000;275(25):19000-8.
1999: Marc Whitlow; Damian O Arnaiz; Brad Buckman; David D Davey; Brian D Griedel; William J Guilford; Sunil Koovakkat; Amy Liang; Raju Mohan; Gary B Phillips; M Seto; Kenneth J Shaw; Wei Xu; Zuchun Zhao; David R Light; Michael M Morrissey
Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 8):1395-404.
1998: Gary B Phillips; Brad Buckman; David D Davey; Keith Eagen; William J Guilford; Josephine W Hinchman; Elena Ho; Sunil Koovakkat; Amy Liang; David R Light; Raju Mohan; Howard P Ng; Joseph M Post; Kenneth J Shaw; D Smith; Babu Subramanyam; Mark E Sullivan; Lan Trinh; Ronald Vergona; Janette Walters; K White; Marc Whitlow; Shung Wu; Wei Xu; Michael M Morrissey
Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme factor Xa.
Journal of medicinal chemistry 1998;41(19):3557-62.
1998: Brad Buckman; Raju Mohan; Sunil Koovakkat; Amy Liang; Lan Trinh; Michael M Morrissey
Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors.
Bioorganic & medicinal chemistry letters 1998;8(16):2235-40.
1998: Raju Mohan; W Yun; Brad Buckman; Amy Liang; Lan Trinh; Michael M Morrissey
Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor XA inhibitors.
Bioorganic & medicinal chemistry letters 1998;8(14):1877-82.
1995: Brad Buckman; T A Bonasera; K S Kirschbaum; Michael J Welch; John A Katzenellenbogen
Fluorine-18-labeled progestin 16 alpha, 17 alpha-dioxolanes: development of high-affinity ligands for the progesterone receptor with high in vivo target site selectivity.
Journal of medicinal chemistry 1995;38(2):328-37.
1994: Brad Buckman; Henry VanBrocklin; C S Dence; Steven Bergmann; Michael J Welch; John A Katzenellenbogen
Synthesis and tissue biodistribution of [omega-11C]palmitic acid. A novel PET imaging agent for cardiac fatty acid metabolism.
Journal of medicinal chemistry 1994;37(15):2481-5.