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Richard Jove

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
30
Turkson, James
18
Yu, Hua
11
Niu, Guilian
10
Bowman, Tammy
10
Coppola, Domenico
9
Garcia, Roy
9
Zhang, Shumin
9
Wu, Jie
9
Mora, Linda
8
Vultur, Adina
8
Buettner, Ralf
8
Huang, Mei
8
Kraker, Alan
7
Haura, Eric
7
Yeatman, Timothy

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Publications

TOP 3
Yu Hua; Pardoll Drew; Jove Richard
STATs in cancer inflammation and immunity: a leading role for STAT3.
Lin Jianping; Buettner Ralf; Yuan Yate-Ching; Yip Richard; Horne David; Jove Richard; Vaidehi Nagarajan
Molecular dynamics simulations of the conformational changes in signal transducers and activators of transcription, Stat1 and Stat3.
Kortylewski Marcin; Swiderski Piotr; Herrmann Andreas; Wang Lin; Kowolik Claudia; Kujawski Maciej; Lee Heehyoung; Scuto Anna; Liu Yong; Yang Chunmei; Deng Jiehui; Soifer Harris S; Raubitschek Andrew; Forman Stephen; Rossi John J; Pardoll Drew M; Jove Richard; Yu Hua
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses.

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All Publications

2009: Yu Hua; Pardoll Drew; Jove Richard
STATs in cancer inflammation and immunity: a leading role for STAT3.
Nature reviews. Cancer 2009;9(11):798-809.
2009: Lin Jianping; Buettner Ralf; Yuan Yate-Ching; Yip Richard; Horne David; Jove Richard; Vaidehi Nagarajan
Molecular dynamics simulations of the conformational changes in signal transducers and activators of transcription, Stat1 and Stat3.
Journal of molecular graphics & modelling 2009;28(4):347-56.
2009: Kortylewski Marcin; Swiderski Piotr; Herrmann Andreas; Wang Lin; Kowolik Claudia; Kujawski Maciej; Lee Heehyoung; Scuto Anna; Liu Yong; Yang Chunmei; Deng Jiehui; Soifer Harris S; Raubitschek Andrew; Forman Stephen; Rossi John J; Pardoll Drew M; Jove Richard; Yu Hua
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses.
Nature biotechnology 2009;27(10):925-32.
2009: Geletu Mulu; Chaize Chrystele; Arulanandam Rozanne; Vultur Adina; Kowolik Claudia; Anagnostopoulou Aikaterini; Jove Richard; Raptis Leda
Stat3 activity is required for gap junctional permeability in normal rat liver epithelial cells.
DNA and cell biology 2009;28(7):319-27.
2009: Homsi Jade; Cubitt Christopher L; Zhang Shumin; Munster Pamela N; Yu Hua; Sullivan Daniel M; Jove Richard; Messina Jane L; Daud Adil I
Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma.
Melanoma research 2009;19(3):167-75.
2009: Lee Heehyoung; Herrmann Andreas; Deng Jie-Hui; Kujawski Maciej; Niu Guilian; Li Zhiwei; Forman Steve; Jove Richard; Pardoll Drew M; Yu Hua
Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors.
Cancer cell 2009;15(4):283-93.
2009: Shain Kenneth H; Yarde Danielle N; Meads Mark B; Huang Mei; Jove Richard; Hazlehurst Lori A; Dalton William S
Beta1 integrin adhesion enhances IL-6-mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation.
Cancer research 2009;69(3):1009-15.
2008: Hillion Joelle; Dhara Surajit; Sumter Takita Felder; Mukherjee Mita; Di Cello Francescopaolo; Belton Amy; Turkson James; Jaganathan Souyma; Cheng Linzhao; Ye Zhaohui; Jove Richard; Aplan Peter; Lin Ying-Wei; Wertzler Kelsey; Reeves Ray; Elbahlouh Ossama; Kowalski Jeanne; Bhattacharya Raka; Resar Linda M S
The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?
Cancer research 2008;68(24):10121-7.
2008: Konig Heiko; Copland Mhairi; Chu Su; Jove Richard; Holyoake Tessa L; Bhatia Ravi
Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells.
Cancer research 2008;68(23):9624-33.
2008: Buettner Ralf; Mesa Tania; Vultur Adina; Lee Frank; Jove Richard
Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells.
Molecular cancer research : MCR 2008;6(11):1766-74.
2008: Yang Fan; Van Meter Timothy E; Buettner Ralf; Hedvat Michael; Liang Wei; Kowolik Claudia M; Mepani Nilesh; Mirosevich Janni; Nam Sangkil; Chen Mike Y; Tye Gary; Kirschbaum Mark; Jove Richard
Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.
Molecular cancer therapeutics 2008;7(11):3519-26.
2008: Cangiano José; Centeno Barbara A; Garrett Christopher R; Cáceres William; de Jesús Ana; Lee Ji-Hyun; Pavía Orestes; Jove Richard; Báez Luis; Sullivan Daniel M; Muro-Cacho Carlos A; Muñoz-Antonia Teresita
Signal transduction proteins in tumors from Puerto Rican and Caucasian gastric adenocarcinoma patients: expression differences with potential for specific targeted therapies.
Digestive diseases and sciences 2008;53(8):2090-100.
2008: Niu Guilian; Briggs Jon; Deng Jiehui; Ma Yihong; Lee Heehyoung; Kortylewski Marcin; Kujawski Maciej; Kay Heidi; Cress W Douglas; Jove Richard; Yu Hua
Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells.
Molecular cancer research : MCR 2008;6(7):1099-105.
2008: Messina Jane L; Yu Hua; Riker Adam I; Munster Pamela N; Jove Richard L; Daud Adil I
Activated stat-3 in melanoma.
Cancer control : journal of the Moffitt Cancer Center 2008;15(3):196-201.
2008: Ozawa Yukiyasu; Williams Ann H; Estes Myka L; Matsushita Norimasa; Boschelli Frank; Jove Richard; List Alan F
Src family kinases promote AML cell survival through activation of signal transducers and activators of transcription (STAT).
Leukemia research 2008;32(6):893-903.
2008: Vultur Adina; Buettner Ralf; Kowolik Claudia; Liang Wei; Smith David; Boschelli Frank; Jove Richard
SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.
Molecular cancer therapeutics 2008;7(5):1185-94.
2008: Scuto Anna; Kirschbaum Mark; Kowolik Claudia; Kretzner Leo; Juhasz Agnes; Atadja Peter; Pullarkat Vinod; Bhatia Ravi; Forman Stephen; Yen Yun; Jove Richard
The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells.
Blood 2008;111(10):5093-100.
2007: Siddiquee Khandaker A Z; Gunning Patrick T; Glenn Matthew; Katt William P; Zhang Shumin; Schrock Christopher; Sebti Said M; Jove Richard; Hamilton Andrew D; Turkson James
An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.
ACS chemical biology 2007;2(12):787-98.
2007: Scuto Anna; Zhang Hongling; Zhao Haiyan; Rivera Maria; Yeatman Timothy J; Jove Richard; Torres-Roca Javier F
RbAp48 regulates cytoskeletal organization and morphology by increasing K-Ras activity and signaling through mitogen-activated protein kinase.
Cancer research 2007;67(21):10317-24.
2007: Buettner Ralf; Huang Mei; Gritsko Tanya; Karras Jim; Enkemann Steve; Mesa Tania; Nam Sangkil; Yu Hua; Jove Richard
Activated signal transducers and activators of transcription 3 signaling induces CD46 expression and protects human cancer cells from complement-dependent cytotoxicity.
Molecular cancer research : MCR 2007;5(8):823-32.
2007: Siddiquee Khandaker; Zhang Shumin; Guida Wayne C; Blaskovich Michelle A; Greedy Benjamin; Lawrence Harshani R; Yip M L Richard; Jove Richard; McLaughlin Mark M; Lawrence Nicholas J; Sebti Said M; Turkson James
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7391-6.
2007: Nam Sangkil; Williams Ann; Vultur Adina; List Alan; Bhalla Kapil; Smith David; Lee Francis Y; Jove Richard
Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells.
Molecular cancer therapeutics 2007;6(4):1400-5.
2007: Gunning Patrick T; Katt William P; Glenn Matthew; Siddiquee Khandaker; Kim Joon S; Jove Richard; Sebti Saïd M; Turkson James; Hamilton Andrew D
Isoform selective inhibition of STAT1 or STAT3 homo-dimerization via peptidomimetic probes: structural recognition of STAT SH2 domains.
Bioorganic & medicinal chemistry letters 2007;17(7):1875-8.
2007: Torres-Roca Javier F; DeSilvio Michelle; Mora Linda B; Khor Li Yan; Hammond Elizabeth; Ahmad Nazeel; Jove Richard; Forman Jeffrey; Lee R Jeffrey; Sandler Howard; Pollack Alan
Activated STAT3 as a correlate of distant metastasis in prostate cancer: a secondary analysis of Radiation Therapy Oncology Group 86-10.
Urology 2007;69(3):505-9.
2007: Shor Audrey C; Keschman Elizabeth A; Lee Francis Y; Muro-Cacho Carlos; Letson G Douglas; Trent Jonathan C; Pledger W Jack; Jove Richard
Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival.
Cancer research 2007;67(6):2800-8.
2006: Anagnostopoulou Aikaterini; Vultur Adina; Arulanandam Rozanne; Cao Jun; Turkson James; Jove Richard; Kim Joon S; Glenn Matthew; Hamilton Andrew D; Raptis Leda
Differential effects of Stat3 inhibition in sparse vs confluent normal and breast cancer cells.
Cancer letters 2006;242(1):120-32.
2006: Mirosevich Janni; Gao Nan; Gupta Aparna; Shappell Scott B; Jove Richard; Matusik Robert J
Expression and role of Foxa proteins in prostate cancer.
The Prostate 2006;66(10):1013-28.
2006: Song Lanxi; Morris Mark; Bagui Tapan; Lee Francis Y; Jove Richard; Haura Eric B
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival.
Cancer research 2006;66(11):5542-8.
2006: Kotha Anupama; Sekharam Madhavi; Cilenti Lucia; Siddiquee Khandaker; Khaled Annette; Zervos Antonis S; Carter Bradford; Turkson James; Jove Richard
Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.
Molecular cancer therapeutics 2006;5(3):621-9.
2006: Diaz Nills; Minton Susan; Cox Charles; Bowman Tammy; Gritsko Tanya; Garcia Roy; Eweis Ibrahim; Wloch Marek; Livingston Sandy; Seijo Ed; Cantor Alan; Lee Ji-Hyun; Beam Craig A; Sullivan Daniel; Jove Richard; Muro-Cacho Carlos A
Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):20-8.
2006: Gritsko Tanya; Williams Ann; Turkson James; Kaneko Satoshi; Bowman Tammy; Huang Mei; Nam Sangkil; Eweis Ibrahim; Diaz Nils; Sullivan Daniel; Yoder Sean; Enkemann Steve; Eschrich Steven; Lee Ji-Hyun; Beam Craig A; Cheng Jin; Minton Susan; Muro-Cacho Carlos A; Jove Richard
Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):11-9.
2006: Riker Adam I; Jove Richard; Daud Adil I
Immunotherapy as part of a multidisciplinary approach to melanoma treatment.
Frontiers in bioscience : a journal and virtual library 2006;11():1-14.
2005: Kortylewski Marcin; Kujawski Maciej; Wang Tianhong; Wei Sheng; Zhang Shumin; Pilon-Thomas Shari; Niu Guilian; Kay Heidi; Mulé James; Kerr William G; Jove Richard; Pardoll Drew; Yu Hua
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity.
Nature medicine 2005;11(12):1314-21.
2005: Park Sungman; Kim Donghwa; Kaneko Satoshi; Szewczyk Kristen M; Nicosia Santo V; Yu Hua; Jove Richard; Cheng Jin Q
Molecular cloning and characterization of the human AKT1 promoter uncovers its up-regulation by the Src/Stat3 pathway.
The Journal of biological chemistry 2005;280(47):38932-41.
2005: Nam Sangkil; Kim Donghwa; Cheng Jin Q; Zhang Shumin; Lee Ji-Hyun; Buettner Ralf; Mirosevich Janni; Lee Francis Y; Jove Richard
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells.
Cancer research 2005;65(20):9185-9.
2005: Niu Guilian; Wright Kenneth L; Ma Yihong; Wright Gabriela M; Huang Mei; Irby Rosalyn; Briggs Jon; Karras James; Cress W Douglas; Pardoll Drew; Jove Richard; Chen Jiangdong; Yu Hua
Role of Stat3 in regulating p53 expression and function.
Molecular and cellular biology 2005;25(17):7432-40.
2005: Turkson James; Zhang Shumin; Mora Linda B; Burns Audrey; Sebti Said; Jove Richard
A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells.
The Journal of biological chemistry 2005;280(38):32979-88.
2005: Torres-Roca Javier F; Eschrich Steven; Zhao Haiyan; Bloom Gregory; Sung Jimmy; McCarthy Susan; Cantor Alan B; Scuto Anna; Li Changgong; Zhang Suming; Jove Richard; Yeatman Timothy
Prediction of radiation sensitivity using a gene expression classifier.
Cancer research 2005;65(16):7169-76.
2005: Xu Qing; Briggs Jon; Park Sungman; Niu Guilian; Kortylewski Marcin; Zhang Shumin; Gritsko Tanya; Turkson James; Kay Heidi; Semenza Gregg L; Cheng Jin Q; Jove Richard; Yu Hua
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways.
Oncogene 2005;24(36):5552-60.
2005: Vultur Adina; Arulanandam Rozanne; Turkson James; Niu Guilian; Jove Richard; Raptis Leda
Stat3 is required for full neoplastic transformation by the Simian Virus 40 large tumor antigen.
Molecular biology of the cell 2005;16(8):3832-46.
2005: Haura Eric B; Turkson James; Jove Richard
Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer.
Nature clinical practice. Oncology 2005;2(6):315-24.
2005: Kortylewski Marcin; Jove Richard; Yu Hua
Targeting STAT3 affects melanoma on multiple fronts.
Cancer metastasis reviews 2005;24(2):315-27.
2005: Dauer Daniel J; Ferraro Bernadette; Song Lanxi; Yu Bin; Mora Linda; Buettner Ralf; Enkemann Steve; Jove Richard; Haura Eric B
Stat3 regulates genes common to both wound healing and cancer.
Oncogene 2005;24(21):3397-408.
2005: Sun Jiazhi; Blaskovich Michelle A; Jove Richard; Livingston Sandra K; Coppola Domenico; Sebti Saïd M
Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity.
Oncogene 2005;24(20):3236-45.
2005: Nam Sangkil; Buettner Ralf; Turkson James; Kim Donghwa; Cheng Jin Q; Muehlbeyer Stephan; Hippe Frankie; Vatter Sandra; Merz Karl-Heinz; Eisenbrand Gerhard; Jove Richard
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(17):5998-6003.
2005: Rahmani Mohamed; Reese Erin; Dai Yun; Bauer Cheryl; Kramer Lora B; Huang Mei; Jove Richard; Dent Paul; Grant Steven
Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change.
Molecular pharmacology 2005;67(4):1166-76.
2004: Turkson James; Zhang Shumin; Palmer Jay; Kay Heidi; Stanko Joseph; Mora Linda B; Sebti Said; Yu Hua; Jove Richard
Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity.
Molecular cancer therapeutics 2004;3(12):1533-42.
2004: Turner Joel G; Engel Roxanne; Derderian Jennifer A; Jove Richard; Sullivan Daniel M
Human topoisomerase IIalpha nuclear export is mediated by two CRM-1-dependent nuclear export signals.
Journal of cell science 2004;117(Pt 14):3061-71.
2004: Vultur Adina; Cao Jun; Arulanandam Rozanne; Turkson James; Jove Richard; Greer Peter; Craig Andrew; Elliott Bruce; Raptis Leda
Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells.
Oncogene 2004;23(15):2600-16.
2004: Turkson James; Kim Joon S; Zhang Shumin; Yuan Jing; Huang Mei; Glenn Matthew; Haura Eric; Sebti Said; Hamilton Andrew D; Jove Richard
Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.
Molecular cancer therapeutics 2004;3(3):261-9.
2004: Savell Jason; Ma Yihong; Morrow Kristin S; Jove Richard; Olashaw Nancy; Moseley Pope L; Cress W Douglas; Wharton Walker
AG490 inhibits G1-S traverse in BALB/c-3T3 cells following either mitogenic stimulation or exogenous expression of E2F-1.
Molecular cancer therapeutics 2004;3(2):205-13.
2004: Yu Hua; Jove Richard
The STATs of cancer--new molecular targets come of age.
Nature reviews. Cancer 2004;4(2):97-105.
2004: Ren Yuan; Meng Songshu; Mei Lin; Zhao Z Joe; Jove Richard; Wu Jie
Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor.
The Journal of biological chemistry 2004;279(9):8497-505.
2004: Wang Tianhong; Niu Guilian; Kortylewski Marcin; Burdelya Lyudmila; Shain Kenneth; Zhang Shumin; Bhattacharya Raka; Gabrilovich Dmitry; Heller Richard; Coppola Domenico; Dalton William; Jove Richard; Pardoll Drew; Yu Hua
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.
Nature medicine 2004;10(1):48-54.
2004: Nefedova Yulia; Huang Mei; Kusmartsev Sergei; Bhattacharya Raka; Cheng Pingyan; Salup Raoul; Jove Richard; Gabrilovich Dmitry
Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):464-74.
2003: Mohapatra Subhra; Chu Baoky; Wei Sheng; Djeu Julie; Epling-Burnette P K; Loughran Thomas; Jove Richard; Pledger W Jackson
Roscovitine inhibits STAT5 activity and induces apoptosis in the human leukemia virus type 1-transformed cell line MT-2.
Cancer research 2003;63(23):8523-30.
2003: Iravani Shohreh; Zhang Hong Q; Yuan Zeng Q; Cheng Jin Q; Karl Richard C; Jove Richard; Coppola Domenico
Modification of insulin-like growth factor 1 receptor, c-Src, and Bcl-XL protein expression during the progression of Barrett's neoplasia.
Human pathology 2003;34(10):975-82.
2003: Sun Mei; Yang Lin; Feldman Richard I; Sun Xia-meng; Bhalla Kapil N; Jove Richard; Nicosia Santo V; Cheng Jin Q
Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src.
The Journal of biological chemistry 2003;278(44):42992-3000.
2003: Cheng Fengdong; Wang Hong-Wei; Cuenca Alex; Huang Mei; Ghansah Tomar; Brayer Jason; Kerr William G; Takeda Kiyoshi; Akira Shizuo; Schoenberger Stephen P; Yu Hua; Jove Richard; Sotomayor Eduardo M
A critical role for Stat3 signaling in immune tolerance.
Immunity 2003;19(3):425-36.
2003: Nimmanapalli Ramadevi; Fuino Lianne; Bali Purva; Gasparetto Maura; Glozak Michele; Tao Jianguo; Moscinski Lynn; Smith Clayton; Wu Jie; Jove Richard; Atadja Peter; Bhalla Kapil
Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells.
Cancer research 2003;63(16):5126-35.
2003: Song Lanxi; Turkson James; Karras James G; Jove Richard; Haura Eric B
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells.
Oncogene 2003;22(27):4150-65.
2003: Raptis Leda; Balboa Valerie; Hsu Tina; Vultur Adina; Turkson James; Jove Richard; Firth Kevin L
In situ electroporation of large numbers of cells using minimal volumes of material.
Analytical biochemistry 2003;317(1):124-8.
2003: Ma Yihong; Yuan Jing; Huang Mei; Jove Richard; Cress W Douglas
Regulation of the cyclin D3 promoter by E2F1.
The Journal of biological chemistry 2003;278(19):16770-6.
2003: Blaskovich Michelle A; Sun Jiazhi; Cantor Alan; Turkson James; Jove Richard; Sebti Saïd M
Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.
Cancer research 2003;63(6):1270-9.
2003: Thomas Christopher Y; Chouinard Michael; Cox Michael; Parsons Sarah; Stallings-Mann Melody; Garcia Roy; Jove Richard; Wharen Robert
Spontaneous activation and signaling by overexpressed epidermal growth factor receptors in glioblastoma cells.
International journal of cancer. Journal international du cancer 2003;104(1):19-27.
2003: Wittmann Sylvie; Bali Purva; Donapaty Sreenivasa; Nimmanapalli Ramadevi; Guo Fei; Yamaguchi Hirohito; Huang Mei; Jove Richard; Wang Hong Gang; Bhalla Kapil
Flavopiridol down-regulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis.
Cancer research 2003;63(1):93-9.
2002: Huang Mei; Dorsey Jay F; Epling-Burnette P K; Nimmanapalli Ramadevi; Landowski Terry H; Mora Linda B; Niu Guilian; Sinibaldi Dominic; Bai Fanqi; Kraker Alan; Yu Hua; Moscinski Lynn; Wei Sheng; Djeu Julie; Dalton William S; Bhalla Kapil; Loughran Thomas P; Wu Jie; Jove Richard
Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells.
Oncogene 2002;21(57):8804-16.
2002: Mora Linda B; Buettner Ralf; Seigne John; Diaz Jose; Ahmad Nazeel; Garcia Roy; Bowman Tammy; Falcone Robert; Fairclough Rita; Cantor Alan; Muro-Cacho Carlos; Livingston Sandy; Karras James; Pow-Sang Julio; Jove Richard
Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells.
Cancer research 2002;62(22):6659-66.
2002: Nimmanapalli Ramadevi; O'Bryan Erica; Huang Mei; Bali Purva; Burnette Pearlie Kay; Loughran Thomas; Tepperberg James; Jove Richard; Bhalla Kapil
Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin.
Cancer research 2002;62(20):5761-9.
2002: Niu Guilian; Bowman Tammy; Huang Mei; Shivers Steve; Reintgen Douglas; Daud Adil; Chang Alfred; Kraker Alan; Jove Richard; Yu Hua
Roles of activated Src and Stat3 signaling in melanoma tumor cell growth.
Oncogene 2002;21(46):7001-10.
2002: Malek Renae L; Irby Rosalyn B; Guo Qingbin M; Lee Kerry; Wong Sylvia; He Mei; Tsai Jennifer; Frank Bryan; Liu Edison T; Quackenbush John; Jove Richard; Yeatman Timothy J; Lee Norman H
Identification of Src transformation fingerprint in human colon cancer.
Oncogene 2002;21(47):7256-65.
2002: Burdelya Lyudmila; Catlett-Falcone Robyn; Levitzki Alexander; Cheng Fengdong; Mora Linda B; Sotomayor Eduardo; Coppola Domenico; Sun JiaZhi; Sebti Said; Dalton William S; Jove Richard; Yu Hua
Combination therapy with AG-490 and interleukin 12 achieves greater antitumor effects than either agent alone.
Molecular cancer therapeutics 2002;1(11):893-9.
2002: Bild Andrea H; Mendoza Francisco J; Gibson Erika M; Huang Mei; Villanueva Jacylyn; Garrington Timothy P; Jove Richard; Johnson Gary L; Gibson Spencer B
MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage.
Oncogene 2002;21(43):6649-56.
2002: Dorsey J F; Cunnick J M; Lanehart R; Huang M; Kraker A J; Bhalla K N; Jove R; Wu J
Interleukin-3 protects Bcr-Abl-transformed hematopoietic progenitor cells from apoptosis induced by Bcr-Abl tyrosine kinase inhibitors.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(9):1589-95.
2002: Velichko Sharlene; Wagner T Charis; Turkson James; Jove Richard; Croze Ed
STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues.
The Journal of biological chemistry 2002;277(38):35635-41.
2002: Bild Andrea H; Turkson James; Jove Richard
Cytoplasmic transport of Stat3 by receptor-mediated endocytosis.
The EMBO journal 2002;21(13):3255-63.
2002: Epling-Burnette P K; Garcia Roy; Bai Fanqi; Ismail Sajid; Loughran Thomas P; Djeu Julie Y; Jove Richard; Wei Sheng
Carboxy-terminal truncated STAT5 is induced by interleukin-2 and GM-CSF in human neutrophils.
Cellular immunology 2002;217(1-2):1-11.
2002: Buettner Ralf; Mora Linda B; Jove Richard
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):945-54.
2002: Niu Guilian; Wright Kenneth L; Huang Mei; Song Lanxi; Haura Eric; Turkson James; Zhang Shumin; Wang Tianhong; Sinibaldi Dominic; Coppola Domenico; Heller Richard; Ellis Lee M; Karras James; Bromberg Jacqueline; Pardoll Drew; Jove Richard; Yu Hua
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.
Oncogene 2002;21(13):2000-8.
2002: Lazaridis Emmanuel N; Sinibaldi Dominic; Bloom Gregory; Mane Shrikant; Jove Richard
A simple method to improve probe set estimates from oligonucleotide arrays.
Mathematical biosciences 2002;176(1):53-8.
2002: Zhang Yu-Wen; Wang Ling-Mei; Jove Richard; Vande Woude George F
Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis.
Oncogene 2002;21(2):217-26.
2001: Oshiro M M; Landowski T H; Catlett-Falcone R; Hazlehurst L A; Huang M; Jove R; Dalton W S
Inhibition of JAK kinase activity enhances Fas-mediated apoptosis but reduces cytotoxic activity of topoisomerase II inhibitors in U266 myeloma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(12):4262-71.
2001: Mora L B; Buettner R; Ahmad N; Bassel Y; Jove R; Seigne J D
Prostate adenocarcinoma: cellular and molecular abnormalities.
Cancer control : journal of the Moffitt Cancer Center 2001;8(6):551-61.
2001: Turkson J; Ryan D; Kim J S; Zhang Y; Chen Z; Haura E; Laudano A; Sebti S; Hamilton A D; Jove R
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.
The Journal of biological chemistry 2001;276(48):45443-55.
2001: Sun M; Wang G; Paciga J E; Feldman R I; Yuan Z Q; Ma X L; Shelley S A; Jove R; Tsichlis P N; Nicosia S V; Cheng J Q
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells.
The American journal of pathology 2001;159(2):431-7.
2001: Bowman T; Broome M A; Sinibaldi D; Wharton W; Pledger W J; Sedivy J M; Irby R; Yeatman T; Courtneidge S A; Jove R
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7319-24.
2001: Epling-Burnette P K; Zhong B; Bai F; Jiang K; Bailey R D; Garcia R; Jove R; Djeu J Y; Loughran T P; Wei S
Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7486-95.
2001: Garcia R; Bowman T L; Niu G; Yu H; Minton S; Muro-Cacho C A; Cox C E; Falcone R; Fairclough R; Parsons S; Laudano A; Gazit A; Levitzki A; Kraker A; Jove R
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells.
Oncogene 2001;20(20):2499-513.
2001: Niu G; Shain K H; Huang M; Ravi R; Bedi A; Dalton W S; Jove R; Yu H
Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest.
Cancer research 2001;61(8):3276-80.
2001: Sakai T; Jove R; Fässler R; Mosher D F
Role of the cytoplasmic tyrosines of beta 1A integrins in transformation by v-src.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3808-13.
2001: Epling-Burnette P K; Liu J H; Catlett-Falcone R; Turkson J; Oshiro M; Kothapalli R; Li Y; Wang J M; Yang-Yen H F; Karras J; Jove R; Loughran T P
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression.
The Journal of clinical investigation 2001;107(3):351-62.
2000: Turkson J; Jove R
STAT proteins: novel molecular targets for cancer drug discovery.
Oncogene 2000;19(56):6613-26.
2000: Sinibaldi D; Wharton W; Turkson J; Bowman T; Pledger W J; Jove R
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling.
Oncogene 2000;19(48):5419-27.
2000: Zhang Y; Turkson J; Carter-Su C; Smithgall T; Levitzki A; Kraker A; Krolewski J J; Medveczky P; Jove R
Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity.
The Journal of biological chemistry 2000;275(32):24935-44.
2000: Dorsey J F; Jove R; Kraker A J; Wu J
The pyrido[2,3-d]pyrimidine derivative PD180970 inhibits p210Bcr-Abl tyrosine kinase and induces apoptosis of K562 leukemic cells.
Cancer research 2000;60(12):3127-31.
2000: Bowman T; Garcia R; Turkson J; Jove R
STATs in oncogenesis.
Oncogene 2000;19(21):2474-88.
2000: Jove R
Preface: STAT signaling.
Oncogene 2000;19(21):2466-7.
2000: Wang Y Z; Wharton W; Garcia R; Kraker A; Jove R; Pledger W J
Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity.
Oncogene 2000;19(17):2075-85.
1999: Lund T C; Coleman C; Horvath E; Sefton B M; Jove R; Medveczky M M; Medveczky P G
The Src-family kinase Lck can induce STAT3 phosphorylation and DNA binding activity.
Cellular signalling 1999;11(11):789-96.
1999: Catlett-Falcone R; Dalton W S; Jove R
STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription.
Current opinion in oncology 1999;11(6):490-6.
1999: Turkson J; Bowman T; Adnane J; Zhang Y; Djeu J Y; Sekharam M; Frank D A; Holzman L B; Wu J; Sebti S; Jove R
Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.
Molecular and cellular biology 1999;19(11):7519-28.
1999: Niu G; Heller R; Catlett-Falcone R; Coppola D; Jaroszeski M; Dalton W; Jove R; Yu H
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo.
Cancer research 1999;59(20):5059-63.
1999: Dalton W S; Jove R
Drug resistance in multiple myeloma: approaches to circumvention.
Seminars in oncology 1999;26(5 Suppl 13):23-7.
1999: Karni R; Jove R; Levitzki A
Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors.
Oncogene 1999;18(33):4654-62.
1999: de Groot R P; Raaijmakers J A; Lammers J W; Jove R; Koenderman L
STAT5 activation by BCR-Abl contributes to transformation of K562 leukemia cells.
Blood 1999;94(3):1108-12.
1999: Shain K H; Jove R; Olashaw N E
Constitutive RelB activation in v-Src-transformed fibroblasts: requirement for IkappaB degradation.
Journal of cellular biochemistry 1999;73(2):237-47.
1999: Liu R Y; Fan C; Garcia R; Jove R; Zuckerman K S
Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines.
Blood 1999;93(7):2369-79.
1999: Irby R B; Mao W; Coppola D; Kang J; Loubeau J M; Trudeau W; Karl R; Fujita D J; Jove R; Yeatman T J
Activating SRC mutation in a subset of advanced human colon cancers.
Nature genetics 1999;21(2):187-90.
1999: Catlett-Falcone R; Landowski T H; Oshiro M M; Turkson J; Levitzki A; Savino R; Ciliberto G; Moscinski L; Fernández-Luna J L; Nuñez G; Dalton W S; Jove R
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells.
Immunity 1999;10(1):105-15.
1999: Lee J H; Harwalkar J A; Bryant S S; Sundaram V; Jove R; Golubic M
Inhibition of neurofibromin and p120 GTPase activating protein (GAP) by dietary fatty acids.
Advances in experimental medicine and biology 1999;469():391-8.
1998: Liu A X; Testa J R; Hamilton T C; Jove R; Nicosia S V; Cheng J Q
AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells.
Cancer research 1998;58(14):2973-7.
1998: Cunnick J M; Dorsey J F; Standley T; Turkson J; Kraker A J; Fry D W; Jove R; Wu J
Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway.
The Journal of biological chemistry 1998;273(23):14468-75.
1998: Turkson J; Bowman T; Garcia R; Caldenhoven E; De Groot R P; Jove R
Stat3 activation by Src induces specific gene regulation and is required for cell transformation.
Molecular and cellular biology 1998;18(5):2545-52.
1998: Iravani S; Mao W; Fu L; Karl R; Yeatman T; Jove R; Coppola D
Elevated c-Src protein expression is an early event in colonic neoplasia.
Laboratory investigation; a journal of technical methods and pathology 1998;78(3):365-71.
1998: Nelson K L; Rogers J A; Bowman T L; Jove R; Smithgall T E
Activation of STAT3 by the c-Fes protein-tyrosine kinase.
The Journal of biological chemistry 1998;273(12):7072-7.
1998: Garcia R; Jove R
Activation of STAT transcription factors in oncogenic tyrosine kinase signaling.
Journal of biomedical science 1998;5(2):79-85.
1998: Golubic M; Harwalkar J A; Bryant S S; Sundaram V; Jove R; Lee J H
Differential regulation of neurofibromin and p120 GTPase-activating protein by nutritionally relevant fatty acids.
Nutrition and cancer 1998;30(2):97-107.
1997: Yu C L; Jove R; Burakoff S J
Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5206-10.
1997: Mao W; Irby R; Coppola D; Fu L; Wloch M; Turner J; Yu H; Garcia R; Jove R; Yeatman T J
Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential.
Oncogene 1997;15(25):3083-90.
1997: Irby R; Mao W; Coppola D; Jove R; Gamero A; Cuthbertson D; Fujita D J; Yeatman T J
Overexpression of normal c-Src in poorly metastatic human colon cancer cells enhances primary tumor growth but not metastatic potential.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(12):1287-95.
1997: Garcia R; Yu C L; Hudnall A; Catlett R; Nelson K L; Smithgall T; Fujita D J; Ethier S P; Jove R
Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(12):1267-76.
1997: Lund T C; Garcia R; Medveczky M M; Jove R; Medveczky P G
Activation of STAT transcription factors by herpesvirus Saimiri Tip-484 requires p56lck.
Journal of virology 1997;71(9):6677-82.
1997: Sartor C I; Dziubinski M L; Yu C L; Jove R; Ethier S P
Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells.
Cancer research 1997;57(5):978-87.
1997: Stancato L F; Silverstein A M; Owens-Grillo J K; Chow Y H; Jove R; Pratt W B
The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase.
The Journal of biological chemistry 1997;272(7):4013-20.
1997: Campbell G S; Yu C L; Jove R; Carter-Su C
Constitutive activation of JAK1 in Src-transformed cells.
The Journal of biological chemistry 1997;272(5):2591-4.
1997: Stofega M R; Yu C L; Wu J; Jove R
Activation of extracellular signal-regulated kinase (ERK) by mitogenic stimuli is repressed in v-Src-transformed cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(1):113-9.
1996: Bryant S S; Mitchell A L; Collins F; Miao W; Marshall M; Jove R
N-terminal sequences contained in the Src homology 2 and 3 domains of p120 GTPase-activating protein are required for full catalytic activity toward Ras.
The Journal of biological chemistry 1996;271(9):5195-9.
1995: Yu C L; Prochownik E V; Jove R
Proximal promoter region of the junB gene mediates attenuation of serum inducibility in Src-transformed cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(12):1513-21.
1995: Bryant S S; Briggs S; Smithgall T E; Martin G A; McCormick F; Chang J H; Parsons S J; Jove R
Two SH2 domains of p120 Ras GTPase-activating protein bind synergistically to tyrosine phosphorylated p190 Rho GTPase-activating protein.
The Journal of biological chemistry 1995;270(30):17947-52.
1995: Yu C L; Meyer D J; Campbell G S; Larner A C; Carter-Su C; Schwartz J; Jove R
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein.
Science (New York, N.Y.) 1995;269(5220):81-3.
1995: Yu H; Suchard S J; Nairn R; Jove R
Dissociation of mitogen-activated protein kinase activation from the oxidative burst in differentiated HL-60 cells and human neutrophils.
The Journal of biological chemistry 1995;270(26):15719-24.
1995: Briggs S D; Bryant S S; Jove R; Sanderson S D; Smithgall T E
The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck.
The Journal of biological chemistry 1995;270(24):14718-24.
1995: Pumiglia K M; LeVine H; Haske T; Habib T; Jove R; Decker S J
A direct interaction between G-protein beta gamma subunits and the Raf-1 protein kinase.
The Journal of biological chemistry 1995;270(24):14251-4.
1995: Chow Y H; Pumiglia K; Jun T H; Dent P; Sturgill T W; Jove R
Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase.
The Journal of biological chemistry 1995;270(23):14100-6.
1995: Pumiglia K; Chow Y H; Fabian J; Morrison D; Decker S; Jove R
Raf-1 N-terminal sequences necessary for Ras-Raf interaction and signal transduction.
Molecular and cellular biology 1995;15(1):398-406.
1994: Dent P; Chow Y H; Wu J; Morrison D K; Jove R; Sturgill T W
Expression, purification and characterization of recombinant mitogen-activated protein kinase kinases.
The Biochemical journal 1994;303 ( Pt 1)():105-12.
1994: Stancato L F; Chow Y H; Owens-Grillo J K; Yem A W; Deibel M R; Jove R; Pratt W B
The native v-Raf.hsp90.p50 heterocomplex contains a novel immunophilin of the FK506 binding class.
The Journal of biological chemistry 1994;269(35):22157-61.
1993: Park S; Jove R
Tyrosine phosphorylation of Ras GTPase-activating protein stabilizes its association with p62 at membranes of v-Src transformed cells.
The Journal of biological chemistry 1993;268(34):25728-34.
1993: Stancato L F; Chow Y H; Hutchison K A; Perdew G H; Jove R; Pratt W B
Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system.
The Journal of biological chemistry 1993;268(29):21711-6.
1993: Hutchison K A; Scherrer L C; Czar M J; Stancato L F; Chow Y H; Jove R; Pratt W B
Regulation of glucocorticoid receptor function through assembly of a receptor-heat shock protein complex.
Annals of the New York Academy of Sciences 1993;684():35-48.
1993: Gregory P E; Gutmann D H; Mitchell A; Park S; Boguski M; Jacks T; Wood D L; Jove R; Collins F S
Neurofibromatosis type 1 gene product (neurofibromin) associates with microtubules.
Somatic cell and molecular genetics 1993;19(3):265-74.
1993: Yu C L; Prochownik E V; Imperiale M J; Jove R
Attenuation of serum inducibility of immediate early genes by oncoproteins in tyrosine kinase signaling pathways.
Molecular and cellular biology 1993;13(4):2011-9.
1992: Redmond T; Brott B K; Jove R; Welsh M J
Localization of the viral and cellular Src kinases to perinuclear vesicles in fibroblasts.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(9):567-76.
1992: Apel I; Yu C L; Wang T; Dobry C; Van Antwerp M E; Jove R; Prochownik E V
Regulation of the junB gene by v-src.
Molecular and cellular biology 1992;12(8):3356-64.
1992: Park S; Liu X; Pawson T; Jove R
Activated Src tyrosine kinase phosphorylates Tyr-457 of bovine GTPase-activating protein (GAP) in vitro and the corresponding residue of rat GAP in vivo.
The Journal of biological chemistry 1992;267(24):17194-200.
1992: Hutchison K A; Stancato L F; Jove R; Pratt W B
The protein-protein complex between pp60v-src and hsp90 is stabilized by molybdate, vanadate, tungstate, and an endogenous cytosolic metal.
The Journal of biological chemistry 1992;267(20):13952-7.
1992: Park S; Marshall M S; Gibbs J B; Jove R
Reconstitution of interactions between the Src tyrosine kinases and Ras GTPase-activating protein using a baculovirus expression system.
The Journal of biological chemistry 1992;267(16):11612-8.
1992: Hutchison K A; Brott B K; De Leon J H; Perdew G H; Jove R; Pratt W B
Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system.
The Journal of biological chemistry 1992;267(5):2902-8.
1991: Brott B K; Decker S; O'Brien M C; Jove R
Molecular features of the viral and cellular Src kinases involved in interactions with the GTPase-activating protein.
Molecular and cellular biology 1991;11(10):5059-67.
1991: Brott B K; Decker S; Shafer J; Gibbs J B; Jove R
GTPase-activating protein interactions with the viral and cellular Src kinases.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(3):755-9.
1989: Jove R; Hanafusa T; Hamaguchi M; Hanafusa H
In vivo phosphorylation states and kinase activities of transforming p60c-src mutants.
Oncogene research 1989;5(1):49-60.
1987: Jove R; Kornbluth S; Hanafusa H
Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region.
Cell 1987;50(6):937-43.
1987: Kornbluth S; Jove R; Hanafusa H
Characterization of avian and viral p60src proteins expressed in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(13):4455-9.
1987: Grass D S; Jove R; Manley J L
RNA polymerase II terminates transcription in vitro in the SV40 origin region.
Nucleic acids research 1987;15(11):4417-36.
1987: Calothy G; Laugier D; Cross F R; Jove R; Hanafusa T; Hanafusa H
The membrane-binding domain and myristylation of p60v-src are not essential for stimulation of cell proliferation.
Journal of virology 1987;61(5):1678-81.
1987: Garber E A; Mayer B J; Jove R; Hanafusa H
Analysis of p60v-src mutants carrying lesions involved in temperature sensitivity.
Journal of virology 1987;61(2):354-60.
1987: Jove R; Hanafusa H
Cell transformation by the viral src oncogene.
Annual review of cell biology 1987;3():31-56.
1986: Mayer B J; Jove R; Krane J F; Poirier F; Calothy G; Hanafusa H
Genetic lesions involved in temperature sensitivity of the src gene products of four Rous sarcoma virus mutants.
Journal of virology 1986;60(3):858-67.
1986: Jove R; Garber E A; Iba H; Hanafusa H
Biochemical properties of p60v-src mutants that induce different cell transformation parameters.
Journal of virology 1986;60(3):849-57.
1986: Jove R; Mayer B J; Iba H; Laugier D; Poirier F; Calothy G; Hanafusa T; Hanafusa H
Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters.
Journal of virology 1986;60(3):840-8.

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