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Bruno Calabretta

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Giovanna Ferrari-Amorotti; Valentina Fragliasso; Giulia Grisendi; Gloria Manzotti; Marco Pieraccioli; Zelia Prudente; Giuseppe Raschellà; Angela Rachele Soliera; Sara Cattelani; Claudia Chiodoni; Mario Paolo Colombo; Massimo Dominici; Roza Esteki; Bruno Calabretta
Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion.
Sara Cattelani; Samantha Cialfi; Raffaella Defferrari; Carlo Dominici; Giovanna Ferrari-Amorotti; Valentina Fragliasso; Sara Galavotti; Clara Guerzoni; Alessandro Inserra; Gloria Manzotti; Heather P McDowell; Chiara Menin; Giuseppe Raschellà; Angela Rachele Soliera; Barbara Tanno; Gian Paolo Tonini; Deborah Tweddle; Luigi Varesio; Jenny Vergalli; Pierluigi Altavista; Maria Luisa Belli; Roberta Bertorelle; Bruno Calabretta
The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform.
A R Soliera; S Addya; A Audia; S Cattelani; Giovanna Ferrari-Amorotti; V Fragliasso; Tessa L Holyoake; Maria Rosa Lidonnici; G Manzotti; Samanta A Mariani; G Perini; L Peterson; Bruno Calabretta
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1.

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All Publications

2013: Giovanna Ferrari-Amorotti; Valentina Fragliasso; Giulia Grisendi; Gloria Manzotti; Marco Pieraccioli; Zelia Prudente; Giuseppe Raschellà; Angela Rachele Soliera; Sara Cattelani; Claudia Chiodoni; Mario Paolo Colombo; Massimo Dominici; Roza Esteki; Bruno Calabretta
Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion.
Cancer research 2013;73(1):235-45.
2012: Sara Cattelani; Samantha Cialfi; Raffaella Defferrari; Carlo Dominici; Giovanna Ferrari-Amorotti; Valentina Fragliasso; Sara Galavotti; Clara Guerzoni; Alessandro Inserra; Gloria Manzotti; Heather P McDowell; Chiara Menin; Giuseppe Raschellà; Angela Rachele Soliera; Barbara Tanno; Gian Paolo Tonini; Deborah Tweddle; Luigi Varesio; Jenny Vergalli; Pierluigi Altavista; Maria Luisa Belli; Roberta Bertorelle; Bruno Calabretta
The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform.
Neoplasia (New York, N.Y.) 2012;14(7):634-43.
2012: A R Soliera; S Addya; A Audia; S Cattelani; Giovanna Ferrari-Amorotti; V Fragliasso; Tessa L Holyoake; Maria Rosa Lidonnici; G Manzotti; Samanta A Mariani; G Perini; L Peterson; Bruno Calabretta
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1.
Leukemia 2012;26(7):1555-63.
2012: G Manzotti; Samanta A Mariani; Giuseppe Raschellà; A R Soliera; J Vergalli; S Cattelani; Vincenzo Cesi; Francesca Corradini; Giovanna Ferrari-Amorotti; V Fragliasso; Tessa L Holyoake; Rita Bussolari; Bruno Calabretta
Expression of p89(c-Mybex9b), an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells.
Blood cancer journal 2012;2(5):e71.
2012: Valentina Fragliasso; Giulia Grisendi; Clara Guerzoni; Gloria Manzotti; Samanta A Mariani; Angela Rachele Soliera; Jenny Vergalli; olivia candini; Sara Cattelani; Yuri Chiodo; Giovanna Ferrari-Amorotti; Bruno Calabretta
Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells.
Journal of cellular biochemistry 2012;113(5):1704-13.
2011: Gaspare La Rocca; Bin Shi; Alessandra Audia; Giovanna Ferrari-Amorotti; Hestia S Mellert; Bruno Calabretta; Steven B McMahon; Laura Sepp-Lorenzino; Renato Baserga
Regulation of microRNA-145 by growth arrest and differentiation.
Experimental cell research 2011;317(4):488-95.
2011: Bruno Calabretta; Paolo Salomoni
Inhibition of autophagy: a new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors.
Leukemia & lymphoma 2011;52 Suppl 1():54-9.
2010: Maria Rosa Lidonnici; Alessandra Audia; Angela Rachele Soliera; Marco Prisco; Giovanna Ferrari-Amorotti; Todd Waldron; Nicholas J Donato; Ying Zhang; Robert V Martinez; Tessa L Holyoake; Bruno Calabretta
Expression of the transcriptional repressor Gfi-1 is regulated by C/EBP{alpha} and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells.
Cancer research 2010;70(20):7949-59.
2010: Giovanna Ferrari-Amorotti; Samanta A Mariani; Chiara Novi; Sara Cattelani; Luisa Pecorari; Francesca Corradini; Angela Rachele Soliera; Gloria Manzotti; Valentina Fragliasso; Ying Zhang; Robert V Martinez; Eric W-F Lam; Clara Guerzoni; Bruno Calabretta
The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain.
The Journal of biological chemistry 2010;285(40):30837-50.
2010: Barbara Tanno; Fabiola Sesti; Vincenzo Cesi; Gianluca Bossi; Giovanna Ferrari-Amorotti; Rita Bussolari; Donatella Tirindelli; Bruno Calabretta; Giuseppe Raschellà
Expression of Slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin.
The Journal of biological chemistry 2010;285(38):29434-45.
2009: Roberta Vitali; Camillo Mancini; Vincenzo Cesi; Barbara Tanno; Marta Piscitelli; Mariateresa Mancuso; Fabiola Sesti; Emanuela Pasquali; Bruno Calabretta; Carlo Dominici; Giuseppe Raschellà
Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model.
International journal of cancer. Journal international du cancer 2009;125(11):2547-55.
2009: Paolo Salomoni; Bruno Calabretta
Targeted therapies and autophagy: new insights from chronic myeloid leukemia.
Autophagy 2009;5(7):1050-1.
2009: Cristian Bellodi; Maria Rosa Lidonnici; Ashley Hamilton; G Vignir Helgason; Angela Rachele Soliera; Mattia Ronchetti; Sara Galavotti; Kenneth W Young; Tommaso Selmi; Rinat Yacobi; Richard A Van Etten; Nicholas J Donato; Ann Hunter; David Dinsdale; Elena Tirrò; Paolo Vigneri; Pierluigi Nicotera; Martin J Dyer; Tessa Holyoake; Paolo Salomoni; Bruno Calabretta
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.
The Journal of clinical investigation 2009;119(5):1109-23.
2009: Luisa Pecorari; Oriano Marin; Chiara Silvestri; Olivia Candini; Elena Rossi; Clara Guerzoni; Sara Cattelani; Samanta A Mariani; Francesca Corradini; Giovanna Ferrari-Amorotti; Laura Cortesi; Rita Bussolari; Giuseppe Raschellà; Massimo R Federico; Bruno Calabretta
Elongation Factor 1 alpha interacts with phospho-Akt in breast cancer cells and regulates their proliferation, survival and motility.
Molecular cancer 2009;8():58.
2008: Angela Rachele Soliera; Maria Rosa Lidonnici; Giovanna Ferrari-Amorotti; Marco Prisco; Ying Zhang; Robert V Martinez; Nicholas J Donato; Bruno Calabretta
Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPalpha in p210BCR/ABL-expressing cells.
Blood 2008;112(5):1942-50.
2008: Roberta Vitali; Camillo Mancini; Vincenzo Cesi; Barbara Tanno; Mariateresa Mancuso; Gianluca Bossi; Ying Zhang; Robert V Martinez; Bruno Calabretta; Carlo Dominici; Giuseppe Raschellà
Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(14):4622-30.
2008: Sara Cattelani; Raffaella Defferrari; Sonia Marsilio; Rita Bussolari; olivia candini; Francesca Corradini; Giovanna Ferrari-Amorotti; Clara Guerzoni; Luisa Pecorari; Chiara Menin; Roberta Bertorelle; Pierluigi Altavista; Heather P McDowell; Renata Boldrini; Carlo Dominici; Gian Paolo Tonini; Giuseppe Raschellà; Bruno Calabretta
Impact of a single nucleotide polymorphism in the MDM2 gene on neuroblastoma development and aggressiveness: results of a pilot study on 239 patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3248-53.
2008: Maria Rosa Lidonnici; Francesca Corradini; Todd Waldron; Timothy P Bender; Bruno Calabretta
Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis.
Blood 2008;111(9):4771-9.
2008: Roberta Vitali; Vincenzo Cesi; Barbara Tanno; Giovanna Ferrari-Amorotti; Carlo Dominici; Bruno Calabretta; Giuseppe Raschellà
Activation of p53-dependent responses in tumor cells treated with a PARC-interacting peptide.
Biochemical and biophysical research communications 2008;368(2):350-6.
2007: Francesca Corradini; Rita Bussolari; Davide Cerioli; Maria Rosa Lidonnici; Bruno Calabretta
A degradation-resistant c-Myb mutant cooperates with Bcl-2 in enhancing proliferative potential and survival of hematopoietic cells.
Blood cells, molecules & diseases 2007;39(3):292-6.
2007: Ji Suk Chang; Ramasamy Santhanam; Rossana Trotta; Paolo Neviani; Anna Eiring; Edward Briercheck; Mattia Ronchetti; Denis C Roy; Bruno Calabretta; Michael A Caligiuri; Danilo Perrotti
High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation.
Blood 2007;110(3):994-1003.
2007: G Iotti; Giovanna Ferrari-Amorotti; C Rosafio; Francesca Corradini; Maria Rosa Lidonnici; M Ronchetti; Michela Bardini; Y Zhang; Robert Martinez; F Blasi; Bruno Calabretta
Expression of CCL9/MIP-1gamma is repressed by BCR/ABL and its restoration suppresses in vivo leukemogenesis of 32D-BCR/ABL cells.
Oncogene 2007;26(24):3482-91.
2007: Mingli Liu; Xiao Tu; Giovanna Ferrari-Amorotti; Bruno Calabretta; Renato Baserga
Downregulation of the upstream binding factor1 by glycogen synthase kinase3beta in myeloid cells induced to differentiate.
Journal of cellular biochemistry 2007;100(5):1154-69.
2007: Rita Bussolari; olivia candini; D Colomer; Francesca Corradini; Clara Guerzoni; Samanta A Mariani; S Cattelani; C Silvestri; L Pecorari; Ilaria Iacobucci; Simona Soverini; Tommaso Fasano; giovanni martinelli; F Cervantes; Bruno Calabretta
Coding sequence and intron-exon junctions of the c-myb gene are intact in the chronic phase and blast crisis stages of chronic myeloid leukemia patients.
Leukemia research 2007;31(2):163-7.
2006: Giovanna Ferrari-Amorotti; Karen Keeshan; Michela Zattoni; Clara Guerzoni; Giorgio Iotti; Sara Cattelani; Nicholas J Donato; Bruno Calabretta
Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha.
Blood 2006;108(4):1353-62.
2006: Clara Guerzoni; Giovanna Ferrari-Amorotti; Michela Bardini; Samanta A Mariani; Bruno Calabretta
Effects of C/EBPalpha and C/EBPbeta in BCR/ABL-expressing cells: differences and similarities.
Cell cycle (Georgetown, Tex.) 2006;5(12):1254-7.
2006: Clara Guerzoni; Michela Bardini; Samanta A Mariani; Giovanna Ferrari-Amorotti; Paolo Neviani; Maria Luisa Panno; Ying Zhang; Robert Martinez; Danilo Perrotti; Bruno Calabretta
Inducible activation of CEBPB, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells.
Blood 2006;107(10):4080-9.
2005: Francesca Corradini; Vincenzo Cesi; Viviana Bartella; Elisabetta Pani; Rita Bussolari; olivia candini; Bruno Calabretta
Enhanced proliferative potential of hematopoietic cells expressing degradation-resistant c-Myb mutants.
The Journal of biological chemistry 2005;280(34):30254-62.
2005: Vincenzo Cesi; Maria Laura Giuffrida; Roberta Vitali; Barbara Tanno; Camillo Mancini; Bruno Calabretta; Giuseppe Raschellà
C/EBP alpha and beta mimic retinoic acid activation of IGFBP-5 in neuroblastoma cells by a mechanism independent from binding to their site.
Experimental cell research 2005;305(1):179-89.
2005: Barbara Tanno; Vincenzo Cesi; Roberta Vitali; F Sesti; Maria Laura Giuffrida; Camillo Mancini; Bruno Calabretta; Giuseppe Raschellà
Silencing of endogenous IGFBP-5 by micro RNA interference affects proliferation, apoptosis and differentiation of neuroblastoma cells.
Cell death and differentiation 2005;12(3):213-23.
2004: Marco Prisco; Arianna Maiorana; Clara Guerzoni; George A Calin; Bruno Calabretta; Renate Voit; Ingrid Grummt; Renato Baserga
Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells.
Molecular and cellular biology 2004;24(12):5421-33.
2004: Bruno Calabretta; Danilo Perrotti
The biology of CML blast crisis.
Blood 2004;103(11):4010-22.
2004: Danilo Perrotti; Bruno Calabretta
Translational regulation by the p210 BCR/ABL oncoprotein.
Oncogene 2004;23(18):3222-9.
2004: Thorsten Zenz; A Roessner; A Thomas; Stefan Fröhling; Hartmut Döhner; Bruno Calabretta; L Dahéron
hIan5: the human ortholog to the rat Ian4/Iddm1/lyp is a new member of the Ian family that is overexpressed in B-cell lymphoid malignancies.
Genes and immunity 2004;5(2):109-16.
2003: Karen Keeshan; Giorgia Santilli; Francesca Corradini; Danilo Perrotti; Bruno Calabretta
Transcription activation function of C/EBPalpha is required for induction of granulocytic differentiation.
Blood 2003;102(4):1267-75.
2003: Danilo Perrotti; Rossana Trotta; Bruno Calabretta
Altered mRNA translation: possible mechanism for CML disease progression.
Cell cycle (Georgetown, Tex.) 2003;2(3):177-80.
2003: Rossana Trotta; Tatiana Vignudelli; olivia candini; Robert V Intine; Luisa Pecorari; Clara Guerzoni; Giorgia Santilli; Mike W Byrom; Silvia Goldoni; Lance P Ford; Michael A Caligiuri; Richard J Maraia; Danilo Perrotti; Bruno Calabretta
BCR/ABL activates mdm2 mRNA translation via the La antigen.
Cancer cell 2003;3(2):145-60.
2002: Danilo Perrotti; Bruno Calabretta
Post-transcriptional mechanisms in BCR/ABL leukemogenesis: role of shuttling RNA-binding proteins.
Oncogene 2002;21(56):8577-83.
2002: Vincenzo Cesi; Barbara Tanno; Roberta Vitali; Camillo Mancini; Maria Laura Giuffrida; Bruno Calabretta; Giuseppe Raschellà
Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation.
Cell death and differentiation 2002;9(11):1232-9.
2002: Barbara Tanno; Anna Negroni; Roberta Vitali; Maria Celeste Pirozzoli; Vincenzo Cesi; Camillo Mancini; Bruno Calabretta; Giuseppe Raschellà
Expression of insulin-like growth factor-binding protein 5 in neuroblastoma cells is regulated at the transcriptional level by c-Myb and B-Myb via direct and indirect mechanisms.
The Journal of biological chemistry 2002;277(26):23172-80.
2002: Angela Iervolino; Giorgia Santilli; Rossana Trotta; Clara Guerzoni; Vincenzo Cesi; Anna Bergamaschi; Carlo Gambacorti-Passerini; Bruno Calabretta; Danilo Perrotti
hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis.
Molecular and cellular biology 2002;22(7):2255-66.
2002: Danilo Perrotti; Vincenzo Cesi; Rossana Trotta; Clara Guerzoni; Giorgia Santilli; Kenneth Campbell; Angela Iervolino; Fabrizio Condorelli; Carlo Gambacorti-Passerini; Michael A Caligiuri; Bruno Calabretta
BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2.
Nature genetics 2002;30(1):48-58.
2001: M A Powzaniuk; Rossana Trotta; Matthew J Loza; A Harth; R V Iozzo; Laurence C Eisenlohr; Bice Perussia; Bruno Calabretta
B-Myb overexpression results in activation and increased Fas/Fas ligand-mediated cytotoxicity of T and NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):242-9.
2001: Fabrizio Condorelli; P Salomoni; S Cotteret; Vincenzo Cesi; Srinivasa M Srinivasula; Emad S Alnemri; Bruno Calabretta
Caspase cleavage enhances the apoptosis-inducing effects of BAD.
Molecular and cellular biology 2001;21(9):3025-36.
2001: Annamaria Biroccio; Barbara Benassi; Igea D'Agnano; Carmen D'Angelo; Simonetta Buglioni; Marcella Mottolese; A Ricciotti; Gennaro Citro; Maurizio Cosimelli; Robert G Ramsay; Bruno Calabretta; Gabriella Zupi
c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings.
The American journal of pathology 2001;158(4):1289-99.
2001: L Dahéron; Thorsten Zenz; Linda D Siracusa; C Brenner; Bruno Calabretta
Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity.
Nucleic acids research 2001;29(6):1308-16.
2001: R Amendola; R Martinez; Anna Negroni; D Venturelli; Barbara Tanno; Bruno Calabretta; Giuseppe Raschellà
DR-nm23 expression affects neuroblastoma cell differentiation, integrin expression, and adhesion characteristics.
Medical and pediatric oncology 2001;36(1):93-6.
2000: M Cirinnà; Rossana Trotta; P Salomoni; P Kossev; Mariusz A Wasik; Danilo Perrotti; Bruno Calabretta
Bcl-2 expression restores the leukemogenic potential of a BCR/ABL mutant defective in transformation.
Blood 2000;96(12):3915-21.
2000: MJ Fernandes; N N Iscove; G Gingras; Bruno Calabretta
Identification and characterization of the gene for a novel C-type lectin (CLECSF7) that maps near the natural killer gene complex on human chromosome 12.
Genomics 2000;69(2):263-70.
2000: Anna Negroni; D Venturelli; Barbara Tanno; R Amendola; S Ransac; Vincenzo Cesi; Bruno Calabretta; Giuseppe Raschellà
Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis.
Cell death and differentiation 2000;7(9):843-50.
2000: Danilo Perrotti; Angela Iervolino; Vincenzo Cesi; M Cirinná; S Lombardini; E Grassilli; S Bonatti; P P Claudio; Bruno Calabretta
BCR-ABL prevents c-jun-mediated and proteasome-dependent FUS (TLS) proteolysis through a protein kinase CbetaII-dependent pathway.
Molecular and cellular biology 2000;20(16):6159-69.
2000: P Salomoni; Fabrizio Condorelli; S M Sweeney; Bruno Calabretta
Versatility of BCR/ABL-expressing leukemic cells in circumventing proapoptotic BAD effects.
Blood 2000;96(2):676-84.
2000: M Cervellera; G Raschella; Giorgia Santilli; Barbara Tanno; Andrea Ventura; Camillo Mancini; Cinzia Sevignani; Bruno Calabretta; A Sala
Direct transactivation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB.
The Journal of biological chemistry 2000;275(28):21055-60.
2000: D Venturelli; Vincenzo Cesi; S Ransac; A Engelhard; Danilo Perrotti; Bruno Calabretta
The nucleoside diphosphate kinase activity of DRnm23 is not required for inhibition of differentiation and induction of apoptosis in 32Dcl3 myeloid precursor cells.
Experimental cell research 2000;257(2):265-71.
2000: L Manzella; R Gualdi; Danilo Perrotti; N C Nicolaides; G Girlando; M A Giuffrida; A Messina; Bruno Calabretta
The interferon regulatory factors 1 and 2 bind to a segment of the human c-myb first intron: possible role in the regulation of c-myb expression.
Experimental cell research 2000;256(1):248-56.
2000: Giulia De Falco; Luigi Bagella; Pier Paolo Claudio; Antonio De Luca; Y Fu; Bruno Calabretta; A Sala; Antonio Giordano
Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation.
Oncogene 2000;19(3):373-9.
2000: A Engelhard; K Campbell; Bruno Calabretta
B-myb alters the response of myeloid precursor cells to G-CSF.
Experimental cell research 2000;254(1):153-62.
1999: Cinzia Sevignani; A Cranston; Renato V Iozzo; Richard Fishel; Bruno Calabretta
Spontaneous and mutagen-induced transformation of primary cultures of Msh2-/- p53-/- colonocytes.
Cancer research 1999;59(23):5882-6.
1999: SD Putney; J Brown; C Cucco; R Lee; Tomasz Skorski; Carlo Leonetti; T Geiser; Bruno Calabretta; Gabriella Zupi; G Zon
Enhanced anti-tumor effects with microencapsulated c-myc antisense oligonucleotide.
Antisense & nucleic acid drug development 1999;9(5):451-8.
1999: Francesca Peruzzi; Marco Prisco; M Dews; P Salomoni; E Grassilli; Gaetano Romano; Bruno Calabretta; Renato Baserga
Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis.
Molecular and cellular biology 1999;19(10):7203-15.
1999: Giuseppe Raschellà; Vincenzo Cesi; R Amendola; Anna Negroni; Barbara Tanno; Pierluigi Altavista; Gian Paolo Tonini; Bruno De Bernardi; Bruno Calabretta
Expression of B-myb in neuroblastoma tumors is a poor prognostic factor independent from MYCN amplification.
Cancer research 1999;59(14):3365-8.
1999: M Majewski; Margaret Nieborowska-Skorska; P Salomoni; Artur Slupianek; Krzysztof Reiss; Rossana Trotta; Bruno Calabretta; Tomasz Skorski
Activation of mitochondrial Raf-1 is involved in the antiapoptotic effects of Akt.
Cancer research 1999;59(12):2815-9.
1999: MJ Fernandes; A A Finnegan; Linda D Siracusa; C Brenner; N N Iscove; Bruno Calabretta
Characterization of a novel receptor that maps near the natural killer gene complex: demonstration of carbohydrate binding and expression in hematopoietic cells.
Cancer research 1999;59(11):2709-17.
1999: E Grassilli; P Salomoni; Danilo Perrotti; Claudio Franceschi; Bruno Calabretta
Resistance to apoptosis in CTLL-2 cells overexpressing B-Myb is associated with B-Myb-dependent bcl-2 induction.
Cancer research 1999;59(10):2451-6.
1999: Margaret Nieborowska-Skorska; Mariusz A Wasik; Artur Slupianek; P Salomoni; T Kitamura; Bruno Calabretta; Tomasz Skorski
Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis.
The Journal of experimental medicine 1999;189(8):1229-42.
1999: Renato V Iozzo; F Chakrani; Danilo Perrotti; David J McQuillan; Tomasz Skorski; Bruno Calabretta; I Eichstetter
Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3092-7.
1998: Tomasz Skorski; Pawel Wlodarski; L Daheron; P Salomoni; Margaret Nieborowska-Skorska; M Majewski; Mariusz A Wasik; Bruno Calabretta
BCR/ABL-mediated leukemogenesis requires the activity of the small GTP-binding protein Rac.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11858-62.
1998: Danilo Perrotti; S Bonatti; Rossana Trotta; Robert Martinez; Tomasz Skorski; P Salomoni; E Grassilli; R V Lozzo; D R Cooper; Bruno Calabretta
TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis.
The EMBO journal 1998;17(15):4442-55.
1998: P Salomoni; Mariusz A Wasik; R F Riedel; Krzysztof Reiss; John K Choi; Tomasz Skorski; Bruno Calabretta
Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant.
The Journal of experimental medicine 1998;187(12):1995-2007.
1998: Giuseppe Raschellà; Barbara Tanno; F Bonetto; Anna Negroni; Pier Paolo Claudio; Alfonso Baldi; R Amendola; Bruno Calabretta; Antonio Giordano; Marco Giorgio Paggi
The RB-related gene Rb2/p130 in neuroblastoma differentiation and in B-myb promoter down-regulation.
Cell death and differentiation 1998;5(5):401-7.
1998: Paolo De Fabritiis; Maria Concetta Petti; Enrico Montefusco; Maria Stefania De Propris; R Sala; Roberto Bellucci; Marco Mancini; A Lisci; F Bonetto; T Geiser; Bruno Calabretta; Franco Mandelli
BCR-ABL antisense oligodeoxynucleotide in vitro purging and autologous bone marrow transplantation for patients with chronic myelogenous leukemia in advanced phase.
Blood 1998;91(9):3156-62.
1998: Cinzia Sevignani; Pawel Wlodarski; J Kirillova; W E Mercer; K G Danielson; Renato V Iozzo; Bruno Calabretta
Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene.
The Journal of clinical investigation 1998;101(8):1572-80.
1998: Pawel Wlodarski; Mariusz A Wasik; Mariusz Z Ratajczak; Cinzia Sevignani; Grazyna Hoser; Jerzy Kawiak; Alan M Gewirtz; Bruno Calabretta; Tomasz Skorski
Role of p53 in hematopoietic recovery after cytotoxic treatment.
Blood 1998;91(8):2998-3006.
1998: Gennaro Citro; Igea D'Agnano; Carlo Leonetti; R Perini; Barbara Bucci; G Zon; Bruno Calabretta; Gabriella Zupi
c-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice.
Cancer research 1998;58(2):283-9.
1998: Tomasz Skorski; Margaret Nieborowska-Skorska; Pawel Wlodarski; Mariusz A Wasik; Rossana Trotta; P Kanakaraj; P Salomoni; M Antonyak; Robert Martinez; M Majewski; A Wong; Bice Perussia; Bruno Calabretta
The SH3 domain contributes to BCR/ABL-dependent leukemogenesis in vivo: role in adhesion, invasion, and homing.
Blood 1998;91(2):406-18.
1997: Tomasz Skorski; Alfonso Bellacosa; Margaret Nieborowska-Skorska; M Majewski; Robert Martinez; John K Choi; Rossana Trotta; Pawel Wlodarski; Danilo Perrotti; Tung O Chan; Mariusz A Wasik; Philip Tsichlis; Bruno Calabretta
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.
The EMBO journal 1997;16(20):6151-61.
1997: R Amendola; R Martinez; Anna Negroni; D Venturelli; Barbara Tanno; Bruno Calabretta; Giuseppe Raschellà
DR-nm23 gene expression in neuroblastoma cells: relationship to integrin expression, adhesion characteristics, and differentiation.
Journal of the National Cancer Institute 1997;89(17):1300-10.
1997: Bruno Calabretta; Tomasz Skorski
Targeting c-myc in leukemia.
Anti-cancer drug design 1997;12(5):373-81.
1997: Manoranjan Santra; D M Mann; E W Mercer; Tomasz Skorski; Bruno Calabretta; Renato V Iozzo
Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases.
The Journal of clinical investigation 1997;100(1):149-57.
1997: Paolo De Fabritiis; Tomasz Skorski; Maria Stefania De Propris; Marco Giorgio Paggi; Margaret Nieborowska-Skorska; A Lisci; Sonia Buffolino; K Campbell; T Geiser; Bruno Calabretta
Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells.
Leukemia 1997;11(6):811-9.
1997: Tomasz Skorski; Danilo Perrotti; Margaret Nieborowska-Skorska; S Gryaznov; Bruno Calabretta
Antileukemia effect of c-myc N3'-->P5' phosphoramidate antisense oligonucleotides in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3966-71.
1997: P Salomoni; Danilo Perrotti; Robert Martinez; Claudio Franceschi; Bruno Calabretta
Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3296-301.
1997: S E DeRocco; Renato V Iozzo; X P Ma; R Schwarting; D Peterson; Bruno Calabretta
Ectopic expression of A-myb in transgenic mice causes follicular hyperplasia and enhanced B lymphocyte proliferation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3240-4.
1997: R Martinez; D Venturelli; Danilo Perrotti; Maria L Veronese; K Kastury; Teresa Druck; Kay Huebner; Bruno Calabretta
Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family.
Cancer research 1997;57(6):1180-7.
1997: A Sala; M Kundu; Ida Casella; A Engelhard; Bruno Calabretta; L Grasso; Marco Giorgio Paggi; Antonio Giordano; R J Watson; Kamel Khalili; Cesare Peschle
Activation of human B-MYB by cyclins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):532-6.
1997: Tomasz Skorski; Margaret Nieborowska-Skorska; Pawel Wlodarski; Danilo Perrotti; Grazyna Hoser; Jerzy Kawiak; M Majewski; L Christensen; Renato V Iozzo; Bruno Calabretta
Treatment of Philadelphia leukemia in severe combined immunodeficient mice by combination of cyclophosphamide and bcr/abl antisense oligodeoxynucleotides.
Journal of the National Cancer Institute 1997;89(2):124-33.
1997: Susanna Scarpa; Anna Negroni; R Amendola; P Signorelli; Bruno Calabretta; Andrea Modesti; Giuseppe Raschellà
Phenotypic and morphological characterization of neuroblastoma cells constitutively expressing B-myb.
Journal of neuro-oncology 1997;31(1-2):107-14.
1997: Bruno Calabretta; Tomasz Skorski
Gene regulatory mechanisms operative on hematopoietic cells: proliferation, differentiation, and neoplasia.
Critical reviews in eukaryotic gene expression 1997;7(1-2):117-24.
1996: Tomasz Skorski; Margaret Nieborowska-Skorska; Pawel Wlodarski; Danilo Perrotti; Robert Martinez; Mariusz A Wasik; Bruno Calabretta
Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13137-42.
1996: Bruno Calabretta; Tomasz Skorski
BCR/ABL regulation of PI-3 kinase activity.
Leukemia & lymphoma 1996;23(5-6):473-6.
1996: Danilo Perrotti; T Bellón; Rossana Trotta; Robert Martinez; Bruno Calabretta
A cell proliferation-dependent multiprotein complex NC-3A positively regulates the CD34 promoter via a TCATTT-containing element.
Blood 1996;88(9):3336-48.
1996: C Cucco; Bruno Calabretta
In vitro and in vivo reversal of multidrug resistance in a human leukemia-resistant cell line by mdr1 antisense oligodeoxynucleotides.
Cancer research 1996;56(19):4332-7.
1996: Tomasz Skorski; Margaret Nieborowska-Skorska; Pawel Wlodarski; G Zon; Renato V Iozzo; Bruno Calabretta
Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice.
Blood 1996;88(3):1005-12.
1996: Donatella Del Bufalo; C Cucco; Carlo Leonetti; Gennaro Citro; Igea D'Agnano; M Benassi; T Geiser; G Zon; Bruno Calabretta; Gabriella Zupi
Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo.
British journal of cancer 1996;74(3):387-93.
1996: P Melotti; Bruno Calabretta
The transcription factors c-myb and GATA-2 act independently in the regulation of normal hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5313-8.
1996: A Sala; Ida Casella; T Bellon; Bruno Calabretta; R J Watson; Cesare Peschle
B-myb promotes S phase and is a downstream target of the negative regulator p107 in human cells.
The Journal of biological chemistry 1996;271(16):9363-7.
1996: S Gryaznov; Tomasz Skorski; C Cucco; Margaret Nieborowska-Skorska; C Y Chiu; D Lloyd; J K Chen; M Koziolkiewicz; Bruno Calabretta
Oligonucleotide N3'-->P5' phosphoramidates as antisense agents.
Nucleic acids research 1996;24(8):1508-14.
1996: Carlo Leonetti; Igea D'Agnano; F Lozupone; A Valentini; T Geiser; G Zon; Bruno Calabretta; C Citro G; Gabriella Zupi
Antitumor effect of c-myc antisense phosphorothioate oligodeoxynucleotides on human melanoma cells in vitro and and in mice.
Journal of the National Cancer Institute 1996;88(7):419-29.
1996: P Melotti; Bruno Calabretta
Induction of hematopoietic commitment and erythromyeloid differentiation in embryonal stem cells constitutively expressing c-myb.
Blood 1996;87(6):2221-34.
1996: Bruno Calabretta; Tomasz Skorski; M Z Ratajczak; Alan M Gewirtz
Antisense strategies in the treatment of leukemias.
Seminars in oncology 1996;23(1):78-87.
1996: Giuseppe Raschellà; Anna Negroni; S Pucci; R Amendola; S Valeri; Bruno Calabretta
B-myb transcriptional regulation and mRNA stability during differentiation of neuroblastoma cells.
Experimental cell research 1996;222(2):395-9.
1996: C Szczylik; T Skórski; L Malaguarnera; J Hetman; S T Chen; Bruno Calabretta
Inhibition of in vitro proliferation of chronic myelogenous leukemia progenitor cells by c-myb antisense oligodeoxynucleotides.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1996;34(3-4):129-34.
1996: M Nieborowska-Skórska; A P Białek; N C Nicolaides; Renato V Iozzo; Maciej Kawalec; Bruno Calabretta; Jerzy Kawiak; K Marlicz; T Skórski
The influence of phosphorothioate oligodeoxynucleotides on various organs in vivo.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1996;34(2):69-73.
1995: Tomasz Skorski; Margaret Nieborowska-Skorska; K Campbell; Renato V Iozzo; G Zon; Zbigniew Darzynkiewicz; Bruno Calabretta
Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes.
The Journal of experimental medicine 1995;182(6):1645-53.
1995: A Sala; T Bellon; P Melotti; Cesare Peschle; Bruno Calabretta
Inhibition of erythro-myeloid differentiation by constitutive expression of a DNA binding-deficient c-myb mutant: implication for c-myb function.
Blood 1995;86(9):3404-12.
1995: Danilo Perrotti; P Melotti; Tomasz Skorski; Ida Casella; Cesare Peschle; Bruno Calabretta
Overexpression of the zinc finger protein MZF1 inhibits hematopoietic development from embryonic stem cells: correlation with negative regulation of CD34 and c-myb promoter activity.
Molecular and cellular biology 1995;15(11):6075-87.
1995: D Venturelli; Robert Martinez; P Melotti; Ida Casella; Cesare Peschle; C Cucco; G Spampinato; Zbigniew Darzynkiewicz; Bruno Calabretta
Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7435-9.
1995: Manoranjan Santra; Tomasz Skorski; Bruno Calabretta; E C Lattime; Renato V Iozzo
De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):7016-20.
1995: Tomasz Skorski; P Kanakaraj; Margaret Nieborowska-Skorska; M Z Ratajczak; S C Wen; G Zon; Alan M Gewirtz; Bice Perussia; Bruno Calabretta
Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells.
Blood 1995;86(2):726-36.
1995: Tomasz Skorski; Margaret Nieborowska-Skorska; C Szczylik; P Kanakaraj; Danilo Perrotti; G Zon; Alan M Gewirtz; Bice Perussia; Bruno Calabretta
C-RAF-1 serine/threonine kinase is required in BCR/ABL-dependent and normal hematopoiesis.
Cancer research 1995;55(11):2275-8.
1995: Giuseppe Raschellà; Anna Negroni; A Sala; S Pucci; A Romeo; Bruno Calabretta
Requirement of b-myb function for survival and differentiative potential of human neuroblastoma cells.
The Journal of biological chemistry 1995;270(15):8540-5.
1995: P de Fabritis; Sergio Amadori; Maria Concetta Petti; Marco Mancini; Enrico Montefusco; Alessandra Picardi; T Geiser; K Campbell; Bruno Calabretta; Franco Mandelli
In vitro purging with BCR-ABL antisense oligodeoxynucleotides does not prevent haematologic reconstitution after autologous bone marrow transplantation.
Leukemia 1995;9(4):662-4.
1995: S C Wen; D H Ku; Antonio De Luca; Pier Paolo Claudio; Antonio Giordano; Bruno Calabretta
ets-2 regulates cdc2 kinase activity in mammalian cells: coordinated expression of cdc2 and cyclin A.
Experimental cell research 1995;217(1):8-14.
1995: Livio Azzoni; I Anegon; Bruno Calabretta; Bice Perussia
Ligand binding to Fc gamma R induces c-myc-dependent apoptosis in IL-2-stimulated NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):491-9.
1995: J Fertała; M Nieborowska-Skórska; Bruno Calabretta; T Skórski
The diverse effect of topoisomerase I specific inhibitor (camptothecin) on normal and BCR/ABL-dependent hematopoietic cells proliferation: therapeutic implications.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1995;33(3):187-92.
1994: X P Ma; Bruno Calabretta
DNA binding and transactivation activity of A-myb, a c-myb-related gene.
Cancer research 1994;54(24):6512-6.
1994: Pier Paolo Claudio; Candace M Howard; Alfonso Baldi; Antonio De Luca; Y Fu; Gianluigi Condorelli; Y Sun; N Colburn; Bruno Calabretta; Antonio Giordano
p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107.
Cancer research 1994;54(21):5556-60.
1994: P Melotti; Bruno Calabretta
Ets-2 and c-Myb act independently in regulating expression of the hematopoietic stem cell antigen CD34.
The Journal of biological chemistry 1994;269(41):25303-9.
1994: Tomasz Skorski; P Kanakaraj; D H Ku; Margaret Nieborowska-Skorska; Eli Canaani; G Zon; Bice Perussia; Bruno Calabretta
Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth.
The Journal of experimental medicine 1994;179(6):1855-65.
1994: Tomasz Skorski; Margaret Nieborowska-Skorska; N C Nicolaides; C Szczylik; P Iversen; Renato V Iozzo; G Zon; Bruno Calabretta
Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4504-8.
1994: G Raschella; A Romeo; Anna Negroni; S Pucci; C Dominici; Manuel A Castello; P Bevilacqua; Armando Felsani; Bruno Calabretta
Lack of correlation between N-myc and MAX expression in neuroblastoma tumors and in cell lines: implication for N-myc-MAX complex formation.
Cancer research 1994;54(8):2251-5.
1994: A Sala; N C Nicolaides; A Engelhard; T Bellon; D C Lawe; A Arnold; X Graña; Antonio Giordano; Bruno Calabretta
Correlation between E2F-1 requirement in the S phase and E2F-1 transactivation of cell cycle-related genes in human cells.
Cancer research 1994;54(6):1402-6.
1994: Gennaro Citro; C Szczylik; Patrizia Ginobbi; Gabriella Zupi; Bruno Calabretta
Inhibition of leukaemia cell proliferation by folic acid-polylysine-mediated introduction of c-myb antisense oligodeoxynucleotides into HL-60 cells.
British journal of cancer 1994;69(3):463-7.
1994: P Melotti; D H Ku; Bruno Calabretta
Regulation of the expression of the hematopoietic stem cell antigen CD34: role of c-myb.
The Journal of experimental medicine 1994;179(3):1023-8.
1994: M Nieborowska-Skórska; M Nakashima; M Ratajczak; Z Steplewski; Bruno Calabretta; T Skórski
Oncogene-targeted antisense oligodeoxynucleotides combined with chemotherapy or immunotherapy: a new approach for tumor treatment?
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1994;32(1):35-40.
1994: M Nieborowska-Skórska; M Z Ratajczak; Bruno Calabretta; T Skórski
The role of c-Myc protooncogene in chronic myelogenous leukemia.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1994;32(4):231-4.
1993: Tomasz Skorski; P Kanakaraj; Margaret Nieborowska-Skorska; M Ratajczak; C Szczylik; G Zon; R B Arlinghaus; Alan M Gewirtz; Bice Perussia; Bruno Calabretta
p120 GAP requirement in normal and malignant human hematopoiesis.
The Journal of experimental medicine 1993;178(6):1923-33.
1993: Paolo De Fabritiis; Sergio Amadori; Bruno Calabretta; Franco Mandelli
Elimination of clonogenic Philadelphia-positive cells using BCR-ABL antisense oligodeoxynucleotides.
Bone marrow transplantation 1993;12(3):261-5.
1993: C Szczylik; Tomasz Skorski; D H Ku; N C Nicolaides; S C Wen; L Rudnicka; A Bonati; L Malaguarnera; Bruno Calabretta
Regulation of proliferation and cytokine expression of bone marrow fibroblasts: role of c-myb.
The Journal of experimental medicine 1993;178(3):997-1005.
1993: Tomasz Skorski; Margaret Nieborowska-Skorska; C Barletta; L Malaguarnera; C Szcyzlik; S T Chen; B Lange; Bruno Calabretta
Highly efficient elimination of Philadelphia leukemic cells by exposure to bcr/abl antisense oligodeoxynucleotides combined with mafosfamide.
The Journal of clinical investigation 1993;92(1):194-202.
1993: Bruno Calabretta; Tomasz Skorski; C Szczylik; G Zon
Prospects for gene-directed therapy with antisense oligodeoxynucleotides.
Cancer treatment reviews 1993;19(2):169-79.
1993: D H Ku; S C Wen; A Engelhard; N C Nicolaides; K E Lipson; T A Marino; Bruno Calabretta
c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene.
The Journal of biological chemistry 1993;268(3):2255-9.
1993: Bruno Calabretta; D Venturelli; Alan M Gewirtz
Functional significance of c-myb expression in normal and leukemic hematopoiesis.
Cancer investigation 1993;11(2):191-7.
1993: M Nieborowska-Skórska; T Skórski; M Z Ratajczak; C Szczylik; L Malaguarnera; Bruno Calabretta
Successful mafosfamide purging of bone marrow from chronic myelogenous leukemia (CML) cells.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1993;31(4):161-7.
1992: Bruno Calabretta; Tomasz Skorski; G Zon
Antisense oligonucleotides.
Seminars in cancer biology 1992;3(6):391-8.
1992: A Sala; Bruno Calabretta
Regulation of BALB/c 3T3 fibroblast proliferation by B-myb is accompanied by selective activation of cdc2 and cyclin D1 expression.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10415-9.
1992: Bruno Calabretta; Tomasz Skorski; C Szczylik; D Caracciolo; Mauro Valtieri; D Venturelli
Protooncogenes in the regulation of normal hematopoiesis. An antisense approach.
Annals of the New York Academy of Sciences 1992;660():117-23.
1992: N C Nicolaides; I Correa; C Casadevall; Salvatore Travali; Kenneth J Soprano; Bruno Calabretta
The Jun family members, c-Jun and JunD, transactivate the human c-myb promoter via an Ap1-like element.
The Journal of biological chemistry 1992;267(27):19665-72.
1992: Giuseppe Raschellà; Anna Negroni; Tomasz Skorski; S Pucci; Margaret Nieborowska-Skorska; A Romeo; Bruno Calabretta
Inhibition of proliferation by c-myb antisense RNA and oligodeoxynucleotides in transformed neuroectodermal cell lines.
Cancer research 1992;52(15):4221-6.
1992: Gennaro Citro; D Perrotti; C Cucco; Igea D'Agnano; Ada Sacchi; Gabriella Zupi; Bruno Calabretta
Inhibition of leukemia cell proliferation by receptor-mediated uptake of c-myb antisense oligodeoxynucleotides.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7031-5.
1992: Mariusz Z Ratajczak; Selina M Luger; K DeRiel; Janet L Abrahm; Bruno Calabretta; Alan M Gewirtz
Role of the KIT protooncogene in normal and malignant human hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1710-4.
1992: Tomasz Skorski; C Szczylik; M Z Ratajczak; L Malaguarnera; Alan M Gewirtz; Bruno Calabretta
Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides.
The Journal of experimental medicine 1992;175(3):743-50.
1992: Bruno Calabretta; N C Nicolaides
c-myb and growth control.
Critical reviews in eukaryotic gene expression 1992;2(3):225-35.
1992: T Skórski; M Nieborowska-Skórska; Bruno Calabretta
A model of Ph' positive chronic myeloid leukemia-blast crisis cell line growth in immunodeficient SCID mice.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1992;30(3):91-6.
1991: N C Nicolaides; R Gualdi; C Casadevall; L Manzella; Bruno Calabretta
Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene.
Molecular and cellular biology 1991;11(12):6166-76.
1991: Bruno Calabretta
Inhibition of protooncogene expression by antisense oligodeoxynucleotides: biological and therapeutic implications.
Cancer research 1991;51(17):4505-10.
1991: Krzysztof Reiss; Salvatore Travali; Bruno Calabretta; Renato Baserga
Growth regulated expression of B-myb in fibroblasts and hematopoietic cells.
Journal of cellular physiology 1991;148(3):338-43.
1991: C Szczylik; Tomasz Skorski; N C Nicolaides; L Manzella; L Malaguarnera; D Venturelli; Alan M Gewirtz; Bruno Calabretta
Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides.
Science (New York, N.Y.) 1991;253(5019):562-5.
1991: Salvatore Travali; A Ferber; Krzysztof Reiss; C Sell; J Koniecki; Bruno Calabretta; Renato Baserga
Effect of the myb gene product on expression of the PCNA gene in fibroblasts.
Oncogene 1991;6(6):887-94.
1991: Bruno Calabretta; R B Sims; Mauro Valtieri; D Caracciolo; C Szczylik; D Venturelli; M Ratajczak; M Beran; Alan M Gewirtz
Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2351-5.
1991: Salvatore Travali; Krzysztof Reiss; A Ferber; S Petralia; WE Mercer; Bruno Calabretta; Renato Baserga
Constitutively expressed c-myb abrogates the requirement for insulinlike growth factor 1 in 3T3 fibroblasts.
Molecular and cellular biology 1991;11(2):731-6.
1991: Alan M Gewirtz; Bruno Calabretta
Role of the c-myb and c-abl protooncogenes in human hematopoiesis.
Annals of the New York Academy of Sciences 1991;628():63-73.
1991: Bruno Calabretta; Alan M Gewirtz
Functional requirements of c-myb during normal and leukemic hematopoiesis.
Critical reviews in oncogenesis 1991;2(3):187-94.
1991: T Skórski; C Szczylik; L Malaguarnera; Bruno Calabretta
Gene-targeted specific inhibition of chronic myeloid leukemia cell growth by BCR-ABL antisense oligodeoxynucleotides.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 1991;29(3):85-9.
1990: D Venturelli; M T Mariano; C Szczylik; Mauro Valtieri; B Lange; W Crist; M Link; Bruno Calabretta
Down-regulated c-myb expression inhibits DNA synthesis of T-leukemia cells in most patients.
Cancer research 1990;50(22):7371-5.
1990: D Venturelli; Salvatore Travali; Bruno Calabretta
Inhibition of T-cell proliferation by a MYB antisense oligomer is accompanied by selective down-regulation of DNA polymerase alpha expression.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5963-7.
1990: Alan M Gewirtz; Bruno Calabretta
Molecular regulation of human megakaryocyte development.
International journal of cell cloning 1990;8(4):267-76.
1990: D Caracciolo; D Venturelli; Mauro Valtieri; C Peschle; Alan M Gewirtz; Bruno Calabretta
Stage-related proliferative activity determines c-myb functional requirements during normal human hematopoiesis.
The Journal of clinical investigation 1990;85(1):55-61.
1989: D Caracciolo; Mauro Valtieri; D Venturelli; C Peschle; Alan M Gewirtz; Bruno Calabretta
Lineage-specific requirement of c-abl function in normal hematopoiesis.
Science (New York, N.Y.) 1989;245(4922):1107-10.
1989: Alan M Gewirtz; G Anfossi; D Venturelli; S Valpreda; R Sims; Bruno Calabretta
G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb.
Science (New York, N.Y.) 1989;245(4914):180-3.
1989: D H Ku; Salvatore Travali; Bruno Calabretta; Kay Huebner; Renato Baserga
Human gene for proliferating cell nuclear antigen has pseudogenes and localizes to chromosome 20.
Somatic cell and molecular genetics 1989;15(4):297-307.
1989: Salvatore Travali; D H Ku; M G Rizzo; L Ottavio; Renato Baserga; Bruno Calabretta
Structure of the human gene for the proliferating cell nuclear antigen.
The Journal of biological chemistry 1989;264(13):7466-72.
1989: G Anfossi; Alan M Gewirtz; Bruno Calabretta
An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3379-83.
1989: Alan M Gewirtz; Bruno Calabretta; B Rucinski; Stefan Niewiarowski; W Y Xu
Inhibition of human megakaryocytopoiesis in vitro by platelet factor 4 (PF4) and a synthetic COOH-terminal PF4 peptide.
The Journal of clinical investigation 1989;83(5):1477-86.
1988: D Jaskulski; C Gatti; Salvatore Travali; Bruno Calabretta; Renato Baserga
Regulation of the proliferating cell nuclear antigen cyclin and thymidine kinase mRNA levels by growth factors.
The Journal of biological chemistry 1988;263(21):10175-9.
1988: D Jaskulski; J K deRiel; WE Mercer; Bruno Calabretta; Renato Baserga
Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA cyclin.
Science (New York, N.Y.) 1988;240(4858):1544-6.
1988: Renato Baserga; Bruno Calabretta; Salvatore Travali; D Jaskulski; K E Lipson; J K deRiel
Regulation of the expression of cell cycle genes.
Annals of the New York Academy of Sciences 1988;551():283-9.
1988: S Ferrari; Bruno Calabretta; R Battini; Stephen C Cosenza; Thomas A Owen; Kenneth J Soprano; Renato Baserga
Expression of c-myc and induction of DNA synthesis by platelet-poor plasma in human diploid fibroblasts.
Experimental cell research 1988;174(1):25-33.
1987: Leszek Kaczmarek; Bruno Calabretta; I B Elfenbein; WE Mercer
Cell cycle analysis of human peripheral blood T lymphocytes in long-term culture.
Experimental cell research 1987;173(1):70-9.
1987: Leszek Kaczmarek; Bruno Calabretta; S Ferrari; Jon K de Riel
Cell-cycle-dependent expression of human ornithine decarboxylase.
Journal of cellular physiology 1987;132(3):545-51.