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Wolfgang Poller

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Sabrina Wilk; Chin-An Yang; Sandra Bauer; Katrin Göldner; Alexander Jenke; Katja Kotsch; Wolfgang Poller; Heinz-Peter Schultheiss; Carsten Skurk; Jenny Stehr; Hans-Dieter Volk; Carmen Scheibenbogen
Adiponectin modulates NK-cell function.
Peter Bobbert; Thomas Bobbert; Alexander Jenke; Uwe Kühl; Dirk Lassner; Wolfgang Poller; Ursula Rauch; Carmen Scheibenbogen; Heinz-Peter Schultheiss; Carsten Skurk
High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy.
Madlen Löbel; Christian Meisel; Wolfgang Poller; Ursula Rauch; Sandra Bauer; Andreas Eisenreich; Robert Kudernatsch; Uwe Kühl; Heinz-Peter Schultheiss; Juliane Tank; Hans-Dieter Volk; Carmen Scheibenbogen
CCN1: a novel inflammation-regulated biphasic immune cell migration modulator.

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2013: Sabrina Wilk; Chin-An Yang; Sandra Bauer; Katrin Göldner; Alexander Jenke; Katja Kotsch; Wolfgang Poller; Heinz-Peter Schultheiss; Carsten Skurk; Jenny Stehr; Hans-Dieter Volk; Carmen Scheibenbogen
Adiponectin modulates NK-cell function.
European journal of immunology 2013;43(4):1024-33.
2012: Peter Bobbert; Thomas Bobbert; Alexander Jenke; Uwe Kühl; Dirk Lassner; Wolfgang Poller; Ursula Rauch; Carmen Scheibenbogen; Heinz-Peter Schultheiss; Carsten Skurk
High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy.
European journal of heart failure 2012;14(11):1265-75.
2012: Madlen Löbel; Christian Meisel; Wolfgang Poller; Ursula Rauch; Sandra Bauer; Andreas Eisenreich; Robert Kudernatsch; Uwe Kühl; Heinz-Peter Schultheiss; Juliane Tank; Hans-Dieter Volk; Carmen Scheibenbogen
CCN1: a novel inflammation-regulated biphasic immune cell migration modulator.
Cellular and molecular life sciences : CMLS 2012;69(18):3101-13.
2012: Mario Kasner; Wolfgang Poller; Heinz-Peter Schultheiss; Paul Steendijk; Stephan Dröse; Dirk Westermann; Carsten Tschöpe
Left ventricular dysfunction induced by nonsevere idiopathic pulmonary arterial hypertension: a pressure-volume relationship study.
American journal of respiratory and critical care medicine 2012;186(2):181-9.
2012: Wolfgang Poller; Madlen Rother; Carsten Skurk; Carmen Scheibenbogen
Endogenous migration modulators as parent compounds for the development of novel cardiovascular and anti-inflammatory drugs.
British journal of pharmacology 2012;165(7):2044-58.
2011: Dirk Westermann; Christin Zietsch; Uwe Völker; Peter Moritz Becher; Stefan Bereswill; Felicitas Escher; Elke Hammer; Markus M Heimesaat; Karin Klingel; Diana Lindner; Johanna Plendl; Wolfgang Poller; Alexander Riad; Kostantinos Savvatis; Heinz-Peter Schultheiss; Carsten Tschöpe
Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy.
Circulation 2011;124(19):2082-93.
2011: Sabrina Wilk; Nalân Utku; Hans D Volk; Sandra Bauer; Diana Elligsen-Merkel; Nicole Goerner; Manuel Guerreiro; Alexander Jenke; Robert Kudernatsch; Jordi Magrane; Wolfgang Poller; Madlen Rother; Carmen Scheibenbogen; Carsten Skurk
Adiponectin is a negative regulator of antigen-activated T cells.
European journal of immunology 2011;41(8):2323-32.
2011: Peter Bobbert; Carmen Scheibenbogen; Alexander Jenke; Gabriele Kania; Sabrina Wilk; Stefanie Krohn; Jenny Stehr; Uwe Kuehl; Ursula Rauch; Urs Eriksson; Heinz-Peter Schultheiss; Wolfgang Poller; Carsten Skurk
Adiponectin expression in patients with inflammatory cardiomyopathy indicates favourable outcome and inflammation control.
European heart journal 2011;32(9):1134-47.
2011: Tanja Pozzuto; Kristina von Kietzell; Thomas Bock; Caroline Schmidt-Lucke; Wolfgang Poller; Thomas Zobel; Dirk Lassner; Heinz Zeichhardt; Stefan Weger; Henry Fechner
Transactivation of human parvovirus B19 gene expression in endothelial cells by adenoviral helper functions.
Virology 2011;411(1):50-64.
2011: Alexander Riad; Dirk Westermann; Christin Zietsch; Konstantinos Savvatis; Peter M Becher; Stefan Bereswill; Markus M Heimesaat; Olga Lettau; Dirk Lassner; Andrea Dörner; Wolfgang Poller; Mathias Busch; Stephan B Felix; Heinz P Schultheiss; Carsten Tschöpe
TRIF is a critical survival factor in viral cardiomyopathy.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(4):2561-70.
2011: Isaac Sipo; Mathias Knauf; Henry Fechner; Wolfgang Poller; Oliver Planz; Reinhard Kurth; Stephen Norley
Vaccine protection against lethal homologous and heterologous challenge using recombinant AAV vectors expressing codon-optimized genes from pandemic swine origin influenza virus (SOIV).
Vaccine 2011;29(8):1690-9.
2011: A Geisler; A Jungmann; Jens Kurreck; Wolfgang Poller; Hugo A Katus; Roland Vetter; Henry Fechner; O J Müller
microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors.
Gene therapy 2011;18(2):199-209.
2011: Henry Fechner; Anja Geisler; Sandra Pinkert; Wolfgang Poller; Jens Kurreck
Pharmacological and biological antiviral therapeutics for cardiac coxsackievirus infections.
Molecules (Basel, Switzerland) 2011;16(10):8475-503.
2011: Dirk Westermann; Diana Lindner; Mario Kasner; Christine Zietsch; K Savvatis; Felicitas Escher; J von Schlippenbach; C Skurk; Paul Steendijk; Alexander Riad; Wolfgang Poller; Heinz-Peter Schultheiss; Carsten Tschöpe
Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.
Circulation. Heart failure 2011;4(1):44-52.
2010: Madlen Rother; Stefanie Krohn; Gabriela Kania; Davy Vanhoutte; Andreas Eisenreich; Xiaomin Wang; Dirk Westermann; Kostas Savvatis; Nadine Dannemann; Carsten Skurk; Denise Hilfiker-Kleiner; Toni Cathomen; Henry Fechner; Ursula Rauch; Heinz-Peter Schultheiss; Stephane Heymans; Urs Eriksson; Carmen Scheibenbogen; Wolfgang Poller
Matricellular signaling molecule CCN1 attenuates experimental autoimmune myocarditis by acting as a novel immune cell migration modulator.
Circulation 2010;122(25):2688-98.
2010: Anne Eckstein; Tobias Grössl; Anja Geisler; Xiaomin Wang; Sandra Pinkert; Tanja Pozzuto; Christina Schwer; Jens Kurreck; Stefan Weger; Roland Vetter; Wolfgang Poller; Henry Fechner
Inhibition of adenovirus infections by siRNA-mediated silencing of early and late adenoviral gene functions.
Antiviral research 2010;88(1):86-94.
2010: Wolfgang Poller; Roger Hajjar; Heinz-Peter Schultheiss; Henry Fechner
Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure.
Cardiovascular research 2010;86(3):353-64.
2010: Wolfgang Poller; Henry Fechner
Development of novel cardiovascular therapeutics from small regulatory RNA molecules--an outline of key requirements.
Current pharmaceutical design 2010;16(20):2252-68.
2009: Sandra Pinkert; Dirk Westermann; Xiaomin Wang; Karin Klingel; Andrea Dörner; Konstantinos Savvatis; Tobias Grössl; Stefanie Krohn; Carsten Tschöpe; Heinz Zeichhardt; Katja Kotsch; Kerstin Weitmann; Wolfgang Hoffmann; Heinz-Peter Schultheiss; O Brad Spiller; Wolfgang Poller; Henry Fechner
Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor.
Circulation 2009;120(23):2358-66.
2009: Denise Werk; Sandra Pinkert; Albert Heim; Heinz Zeichhardt; Hans-Peter Grunert; Wolfgang Poller; Volker A Erdmann; Henry Fechner; Jens Kurreck
Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic antiviral activity against coxsackievirus B3.
Antiviral research 2009;83(3):298-306.
2009: Robert Fischer; Wolfgang Poller; Heinz-Peter Schultheiss; Michael Gotthardt
CAR-diology--a virus receptor in the healthy and diseased heart.
Journal of molecular medicine (Berlin, Germany) 2009;87(9):879-84.
2009: Silvio Antoniak; U Boltzen; A Eisenreich; Caroline Stellbaum; Wolfgang Poller; Heinz-Peter Schultheiss; Ursula Rauch
Regulation of cardiomyocyte full-length tissue factor expression and microparticle release under inflammatory conditions in vitro.
Journal of thrombosis and haemostasis : JTH 2009;7(5):871-8.
2009: Yu Shi; Chen Chen; Ulrike Lisewski; Uta Wrackmeyer; Michael Radke; Dirk Westermann; Martina Sauter; Carsten Tschöpe; Wolfgang Poller; Karin Klingel; Michael Gotthardt
Cardiac deletion of the Coxsackievirus-adenovirus receptor abolishes Coxsackievirus B3 infection and prevents myocarditis in vivo.
Journal of the American College of Cardiology 2009;53(14):1219-26.
2009: Andreas Eisenreich; Vladimir Y Bogdanov; Andreas Zakrzewicz; Axel R Pries; Silvio Antoniak; Wolfgang Poller; Heinz-Peter Schultheiss; Ursula Rauch
Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells.
Circulation research 2009;104(5):589-99.
2009: Lennart Suckau; Henry Fechner; Elie Chemaly; Stefanie Krohn; Lahouaria Hadri; Jens Kockskämper; Dirk Westermann; Egbert Bisping; Hung Ly; Xiaomin Wang; Yoshiaki Kawase; Jiqiu Chen; Lifan Liang; Isaac Sipo; Roland Vetter; Stefan Weger; Jens Kurreck; Volker Erdmann; Carsten Tschope; Burkert Pieske; Djamel Lebeche; Heinz-Peter Schultheiss; Roger J Hajjar; Wolfgang Poller
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy.
Circulation 2009;119(9):1241-52.
2008: Matthias Holzmann; Alexander Nicko; Uwe Kühl; Michel Noutsias; Wolfgang Poller; Wolfgang Hoffmann; Andreas Morguet; Bernhard Witzenbichler; Carsten Tschöpe; Heinz-Peter Schultheiss; Matthias Pauschinger
Complication rate of right ventricular endomyocardial biopsy via the femoral approach: a retrospective and prospective study analyzing 3048 diagnostic procedures over an 11-year period.
Circulation 2008;118(17):1722-8.
2008: Andreas Eisenreich; Ulrike Boltzen; Wolfgang Poller; Heinz-Peter Schultheiss; Ursula Rauch
Effects of the Cdc2-like kinase-family and DNA topoisomerase I on the alternative splicing of eNOS in TNF-alpha-stimulated human endothelial cells.
Biological chemistry 2008;389(10):1333-8.
2008: Ulrike Lisewski; Yu Shi; Uta Wrackmeyer; Robert Fischer; Chen Chen; Alexander Schirdewan; Rene Jüttner; Fritz G Rathjen; Wolfgang Poller; Michael H Radke; Michael Gotthardt
The tight junction protein CAR regulates cardiac conduction and cell-cell communication.
The Journal of experimental medicine 2008;205(10):2369-79.
2008: Henry Fechner; Isaac Sipo; Dirk Westermann; Sandra Pinkert; Xiaomin Wang; Lennart Suckau; Jens Kurreck; Heinz Zeichhardt; Oliver Müller; Roland Vetter; Volker A Erdmann; Carsten Tschope; Wolfgang Poller
Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy.
Journal of molecular medicine (Berlin, Germany) 2008;86(9):987-97.
2008: Petra Goldin-Lang; Quoc-Viet Tran; Iduna Fichtner; Andreas Eisenreich; Silvio Antoniak; Karsten Schulze; Sarah E Coupland; Wolfgang Poller; Heinz-Peter Schultheiss; Ursula Rauch
Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis.
Oncology reports 2008;20(1):123-8.
2008: Uwe Kühl; Dirk Lassner; Matthias Pauschinger; Ulrich Gross; Bettina Seeberg; Michel Noutsias; Wolfgang Poller; Heinz-Peter Schultheiss
Prevalence of erythrovirus genotypes in the myocardium of patients with dilated cardiomyopathy.
Journal of medical virology 2008;80(7):1243-51.
2008: Felicitas Escher; Uwe Kuhl; Titus Mbah Sabi; Lennart Suckau; Dirk Lassner; Wolfgang Poller; Heinz-Peter Schultheiss; Michel Noutsias
Immunohistological detection of Parvovirus B19 capsid proteins in endomyocardial biopsies from dilated cardiomyopathy patients.
Medical science monitor : international medical journal of experimental and clinical research 2008;14(6):CR333-338.
2008: Carsten Skurk; Frank Wittchen; Lennart Suckau; Henning Witt; Michel Noutsias; Henry Fechner; Heinz-Peter Schultheiss; Wolfgang Poller
Description of a local cardiac adiponectin system and its deregulation in dilated cardiomyopathy.
European heart journal 2008;29(9):1168-80.
2008: Dirk Westermann; Mario Kasner; Paul Steendijk; Frank Spillmann; Alexander Riad; Kerstin Weitmann; Wolfgang Hoffmann; Wolfgang Poller; Matthias Pauschinger; Heinz-Peter Schultheiss; Carsten Tschöpe
Role of left ventricular stiffness in heart failure with normal ejection fraction.
Circulation 2008;117(16):2051-60.
2008: Michel Noutsias; Maria Rohde; Andrea Block; Katrin Klippert; Olga Lettau; Katja Blunert; Michael Hummel; Uwe Kühl; Hans Lehmkuhl; Roland Hetzer; Ursula Rauch; Wolfgang Poller; Matthias Pauschinger; Heinz-Peter Schultheiss; Hans D Volk; Katja Kotsch
Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies.
BMC molecular biology 2008;9():3.
2007: Isaac Sipo; Henry Fechner; Sandra Pinkert; Lennart Suckau; Xiaomin Wang; Stefan Weger; Wolfgang Poller
Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction.
Gene therapy 2007;14(18):1319-29.
2007: Mario Kasner; Dirk Westermann; Paul Steendijk; Regina Gaub; Ursula Wilkenshoff; Kerstin Weitmann; Wolfgang Hoffmann; Wolfgang Poller; Heinz-Peter Schultheiss; Matthias Pauschinger; Carsten Tschöpe
Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative Doppler-conductance catheterization study.
Circulation 2007;116(6):637-47.
2007: Petra Goldin-Lang; Klaus Pels; Quoc-Viet Tran; Björn Szotowski; Frank Wittchen; Silvio Antoniak; Tobias Willich; Henning Witt; Michael Hummel; Dido Lenze; Wolfgang Poller; Heinz-Peter Schultheiss; Ursula Rauch
Effect of ionizing radiation on cellular procoagulability and co-ordinated gene alterations.
Haematologica 2007;92(8):1091-8.
2007: Angela Kallwellis-Opara; Andrea Dörner; Wolfgang Poller; Michel Noutsias; Uwe Kühl; Heinz-Peter Schultheiss; Matthias Pauschinger
Autoimmunological features in inflammatory cardiomyopathy.
Clinical research in cardiology : official journal of the German Cardiac Society 2007;96(7):469-80.
2007: Henry Fechner; Sandra Pinkert; Xiaomin Wang; Isaac Sipo; Lennart Suckau; Jens Kurreck; Andrea Dörner; K Sollerbrant; Heinz Zeichhardt; Hans-Peter Grunert; Roland Vetter; Heinz-Peter Schultheiss; Wolfgang Poller
Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor.
Gene therapy 2007;14(12):960-71.
2007: Frank Wittchen; Lennart Suckau; Henning Witt; C Skurk; Dirk Lassner; Henry Fechner; Isaac Sipo; Ute Ungethüm; Patricia Ruiz; Matthias Pauschinger; Carsten Tschope; Ursula Rauch; Uwe Kühl; Heinz-Peter Schultheiss; Wolfgang Poller
Genomic expression profiling of human inflammatory cardiomyopathy (DCMi) suggests novel therapeutic targets.
Journal of molecular medicine (Berlin, Germany) 2007;85(3):257-71.
2007: Henry Fechner; Lennart Suckau; Jens Kurreck; Isaac Sipo; Xiaomin Wang; Sandra Pinkert; S Loschen; J Rekittke; Stefan Weger; Dick H W Dekkers; Roland Vetter; Volker A Erdmann; Heinz-Peter Schultheiss; Martin Paul; Jos M J Lamers; Wolfgang Poller
Highly efficient and specific modulation of cardiac calcium homeostasis by adenovector-derived short hairpin RNA targeting phospholamban.
Gene therapy 2007;14(3):211-8.
2007: Henry Fechner; Xiaomin Wang; Almudena Hurtado Picó; Judith Wildner; Lennart Suckau; Sandra Pinkert; Isaac Sipo; Stefan Weger; Wolfgang Poller
A bidirectional Tet-dependent promotor construct regulating the expression of E1A for tight control of oncolytic adenovirus replication.
Journal of biotechnology 2007;127(4):560-74.
2007: Jun Li; Sebastian Leschka; Susanne Rutschow; Peter L Schwimmbeck; Lars Husmann; Michel Noutsias; Dirk Westermann; Wolfgang Poller; Heinz Zeichhardt; Karin Klingel; Carsten Tschope; Heinz-Peter Schultheiss; Matthias Pauschinger
Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis.
European journal of pharmacology 2007;554(1):60-8.
2006: Carsten Tschöpe; Dirk Westermann; Paul Steendijk; Mario Kasner; Martin Rudwaleit; Peter L Schwimmbeck; Wolfgang Poller; Heinz-Peter Schultheiss
Coronary vasospasm-induced acute diastolic dysfunction in a patient with Raynaud's phenomenon.
Clinical research in cardiology : official journal of the German Cardiac Society 2006;95(6):344-8.
2006: Isaac Sipo; Almudena Hurtado Picó; Xiaomin Wang; Jürgen Eberle; Iver Petersen; Stefan Weger; Wolfgang Poller; Henry Fechner
An improved Tet-On regulatable FasL-adenovirus vector system for lung cancer therapy.
Journal of molecular medicine (Berlin, Germany) 2006;84(3):215-25.
2006: Wolfgang Poller; Heinz-Peter Schultheiss; Uwe Kühl
Viruses and other environmental factors as possible sources of phenotypic heterogeneity in familial dilated cardiomyopathy.
Journal of the American College of Cardiology 2006;47(3):689-90; author reply 690.
2006: Uwe Kühl; Matthias Pauschinger; Wolfgang Poller; Heinz-Peter Schultheiss
Anti-viral treatment in patients with virus-induced cardiomyopathy.
Ernst Schering Research Foundation workshop 2006;(55):323-42.
2006: Wolfgang Poller; Henry Fechner; Uwe Kühl; Matthias Pauschinger; Heinz-Peter Schultheiss
New therapeutics targets in chronic viral cardiomyopathy.
Ernst Schering Research Foundation workshop 2006;(55):287-303.
2006: Isaac Sipo; Xiaomin Wang; Almudena Hurtado Picó; Lennart Suckau; Stefan Weger; Wolfgang Poller; Henry Fechner
Tamoxifen-regulated adenoviral E1A chimeras for the control of tumor selective oncolytic adenovirus replication in vitro and in vivo.
Gene therapy 2006;13(2):173-86.
2006: Andrea Dörner; Stefanie Giessen; Regina Gaub; Helga Grosse Siestrup; Peter L Schwimmbeck; Roland Hetzer; Wolfgang Poller; Heinz-Peter Schultheiss
An isoform shift in the cardiac adenine nucleotide translocase expression alters the kinetic properties of the carrier in dilated cardiomyopathy.
European journal of heart failure 2006;8(1):81-9.
2005: Heinz-Peter Schultheiss; Michel Noutsias; Uwe Kühl; Ulrich Gross; Dirk Lassner; Wolfgang Poller; Matthias Pauschinger
[Cardiomyopathies II. Hypertrophic cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy].
Der Internist 2005;46(12):1373-85, quiz 1386-7.
2005: Heinz-Peter Schultheiss; Michel Noutsias; Uwe Kühl; Dirk Lassner; Ulrich Gross; Wolfgang Poller; Matthias Pauschinger
[Cardiomyopathies. I: classification of cardiomyopathies--dilated cardiomyopathy].
Der Internist 2005;46(11):1245-56; quiz 1257.
2005: Carsten Tschöpe; Mario Kasner; Dirk Westermann; Regina Gaub; Wolfgang Poller; Heinz-Peter Schultheiss
The role of NT-proBNP in the diagnostics of isolated diastolic dysfunction: correlation with echocardiographic and invasive measurements.
European heart journal 2005;26(21):2277-84.
2005: Uwe Kühl; Matthias Pauschinger; Bettina Seeberg; Dirk Lassner; Michel Noutsias; Wolfgang Poller; Heinz-Peter Schultheiss
Viral persistence in the myocardium is associated with progressive cardiac dysfunction.
Circulation 2005;112(13):1965-70.
2005: Wolfgang Poller; Uwe Kühl; Carsten Tschoepe; Matthias Pauschinger; Henry Fechner; Heinz-Peter Schultheiss
Genome-environment interactions in the molecular pathogenesis of dilated cardiomyopathy.
Journal of molecular medicine (Berlin, Germany) 2005;83(8):579-86.
2005: Björn Szotowski; Silvio Antoniak; Wolfgang Poller; Heinz-Peter Schultheiss; Ursula Rauch
Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines.
Circulation research 2005;96(12):1233-9.
2005: Carsten Tschöpe; Mario Kasner; Dirk Westermann; Thomas Walther; Regina Gaub; Wolfgang Poller; Heinz-Peter Schultheiss
Elevated NT-ProBNP levels in patients with increased left ventricular filling pressure during exercise despite preserved systolic function.
Journal of cardiac failure 2005;11(5 Suppl):S28-33.
2005: Matthias Pauschinger; Susanne Rutschow; Kumaran Chandrasekharan; Dirk Westermann; Anneke Weitz; Lothar Peter Schwimmbeck; Heinz Zeichhardt; Wolfgang Poller; Michel Noutsias; Jun Li; Heinz-Peter Schultheiss; Carsten Tschope
Carvedilol improves left ventricular function in murine coxsackievirus-induced acute myocarditis association with reduced myocardial interleukin-1beta and MMP-8 expression and a modulated immune response.
European journal of heart failure 2005;7(4):444-52.
2005: Björn Szotowski; Petra Goldin-Lang; Silvio Antoniak; Vladimir Y Bogdanov; Delano Pathirana; Matthias Pauschinger; Andrea Dörner; Uwe Kuehl; Sarah E Coupland; Yale Nemerson; Michael Hummel; Wolfgang Poller; Roland Hetzer; Heinz-Peter Schultheiss; Ursula Rauch
Alterations in myocardial tissue factor expression and cellular localization in dilated cardiomyopathy.
Journal of the American College of Cardiology 2005;45(7):1081-9.
2005: Almudena Hurtado Picó; Xiaomin Wang; Isaac Sipo; Ulrike Siemetzki; Jürgen Eberle; Wolfgang Poller; Henry Fechner
Viral and nonviral factors causing nonspecific replication of tumor- and tissue-specific promoter-dependent oncolytic adenoviruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(4):563-77.
2005: Carsten Tschöpe; C-T Bock; Mario Kasner; Michel Noutsias; Dirk Westermann; Peter L Schwimmbeck; Matthias Pauschinger; Wolfgang Poller; Uwe Kühl; Reinhard Kandolf; Heinz-Peter Schultheiss
High prevalence of cardiac parvovirus B19 infection in patients with isolated left ventricular diastolic dysfunction.
Circulation 2005;111(7):879-86.
2005: Uwe Kühl; Matthias Pauschinger; Michel Noutsias; Bettina Seeberg; Thomas Bock; Dirk Lassner; Wolfgang Poller; Reinhard Kandolf; Heinz-Peter Schultheiss
High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction.
Circulation 2005;111(7):887-93.
2004: Wolfgang Poller; Henry Fechner; Jens Kurreck; Matthias Pauschinger; Uwe Kühl; Volker A Erdmann; Jos M J Lamers; Heinz-Peter Schultheiss
Nucleic acid-based modulation of cardiac gene expression for the treatment of cardiac diseases. Approaches and perspectives.
Zeitschrift für Kardiologie 2004;93(3):171-93.
2004: Haili Wang; Markus Kroeber; Michael Hanke; Rainer Ries; Carsten Schmid; Wolfgang Poller; Wiltrud Richter
Release of active and depot GDF-5 after adenovirus-mediated overexpression stimulates rabbit and human intervertebral disc cells.
Journal of molecular medicine (Berlin, Germany) 2004;82(2):126-34.
2004: Michel Noutsias; Matthias Pauschinger; Wolfgang Poller; Heinz-Peter Schultheiss; Uwe Kühl
Immunomodulatory treatment strategies in inflammatory cardiomyopathy: current status and future perspectives.
Expert review of cardiovascular therapy 2004;2(1):37-51.
2003: Mahmoud A Srour; Henry Fechner; Xiaomin Wang; Ulrike Siemetzki; Thilo Albert; Johannes Oldenburg; Peter Hanfland; Wolfgang Poller; Hans H Brackmann; Rainer Schwaab
Regulation of human factor IX expression using doxycycline-inducible gene expression system.
Thrombosis and haemostasis 2003;90(3):398-405.
2003: Henry Fechner; Xiaomin Wang; M Srour; Ulrike Siemetzki; Holger Seltmann; Andreas P Sutter; Hans Scherübl; Christos Zouboulis; Rainer Schwaab; Wolfgang Hillen; Heinz-Peter Schultheiss; Wolfgang Poller
A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication.
Gene therapy 2003;10(19):1680-90.
2003: Uwe Kühl; Matthias Pauschinger; Thomas Bock; Karin Klingel; C Peter Lothar Schwimmbeck; Bettina Seeberg; Lars Krautwurm; Wolfgang Poller; Heinz-Peter Schultheiss; Reinhard Kandolf
Parvovirus B19 infection mimicking acute myocardial infarction.
Circulation 2003;108(8):945-50.
2003: Uwe Kühl; Matthias Pauschinger; Peter L Schwimmbeck; Bettina Seeberg; Conny Lober; Michel Noutsias; Wolfgang Poller; Heinz-Peter Schultheiss
Interferon-beta treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction.
Circulation 2003;107(22):2793-8.
2003: Henry Fechner; Michel Noutsias; Carsten Tschoepe; Kerstin Hinze; Xiaomin Wang; Felicitas Escher; Matthias Pauschinger; Dick H W Dekkers; Roland Vetter; Martin Paul; Jos M J Lamers; Heinz-Peter Schultheiss; Wolfgang Poller
Induction of coxsackievirus-adenovirus-receptor expression during myocardial tissue formation and remodeling: identification of a cell-to-cell contact-dependent regulatory mechanism.
Circulation 2003;107(6):876-82.
2003: Michel Noutsias; Matthias Pauschinger; Wolfgang Poller; Heinz-Peter Schultheiss; Uwe Kühl
Current insights into the pathogenesis, diagnosis and therapy of inflammatory cardiomyopathy.
Heart failure monitor 2003;3(4):127-35.
2003: Henry Fechner; Pamela E Johnston; Nicholas J Sharp; Paul Montague; Ian R Griffiths; Xiaomin Wang; Natasha Olby; Alfred Looman; Wolfgang Poller; Thomas Flegel
Molecular genetic and expression analysis of alpha-tocopherol transfer protein mRNA in German shepherd dogs with degenerative myelopathy.
Berliner und Münchener tierärztliche Wochenschrift 2003;116(1-2):31-6.
2002: Ralph Knöll; Masahiko Hoshijima; Hal M Hoffman; Veronika Person; Ilka Lorenzen-Schmidt; Marie-Louise Bang; Takeharu Hayashi; Nobuyuki Shiga; Hideo Yasukawa; Wolfgang Schaper; William McKenna; Mitsuhiro Yokoyama; Nicholas J Schork; Jeffrey H Omens; Andrew D McCulloch; Akinori Kimura; Carol C Gregorio; Wolfgang Poller; Jutta Schaper; Heinz-Peter Schultheiss; Kenneth R Chien
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy.
Cell 2002;111(7):943-55.
2002: Wolfgang Poller; Henry Fechner; Michel Noutsias; Carsten Tschoepe; Heinz-Peter Schultheiss
Highly variable expression of virus receptors in the human cardiovascular system. Implications for cardiotropic viral infections and gene therapy.
Zeitschrift für Kardiologie 2002;91(12):978-91.
2002: Jun Li; Peter L Schwimmbeck; Carsten Tschope; Sebastian Leschka; Lars Husmann; Susanne Rutschow; Florian Reichenbach; Michel Noutsias; Ursula Kobalz; Wolfgang Poller; Frank Spillmann; Heinz Zeichhardt; Heinz-Peter Schultheiss; Matthias Pauschinger
Collagen degradation in a murine myocarditis model: relevance of matrix metalloproteinase in association with inflammatory induction.
Cardiovascular research 2002;56(2):235-47.
2001: Christina Warnecke; D Kaup; U Marienfeld; Wolfgang Poller; C Yankah; Michael Gräfe; Eckart Fleck; Vera Regitz-Zagrosek
Adenovirus-mediated overexpression and stimulation of the human angiotensin II type 2 receptor in porcine cardiac fibroblasts does not modulate proliferation, collagen I mRNA expression and ERK1/ERK2 activity, but inhibits protein tyrosine phosphatases.
Journal of molecular medicine (Berlin, Germany) 2001;79(9):510-21.
2001: Michel Noutsias; Henry Fechner; H de Jonge; Xiaomin Wang; Dick H W Dekkers; A B Houtsmuller; Matthias Pauschinger; J Bergelson; Rahat S Warraich; M Yacoub; R Hetzer; Jos M J Lamers; Heinz-Peter Schultheiss; Wolfgang Poller
Human coxsackie-adenovirus receptor is colocalized with integrins alpha(v)beta(3) and alpha(v)beta(5) on the cardiomyocyte sarcolemma and upregulated in dilated cardiomyopathy: implications for cardiotropic viral infections.
Circulation 2001;104(3):275-80.
2000: Henry Fechner; Xiaomin Wang; H Wang; A Jansen; Matthias Pauschinger; Hans Scherübl; J M Bergelson; Heinz-Peter Schultheiss; Wolfgang Poller
Trans-complementation of vector replication versus Coxsackie-adenovirus-receptor overexpression to improve transgene expression in poorly permissive cancer cells.
Gene therapy 2000;7(22):1954-68.
2000: Albert Smolenski; Wolfgang Poller; Ulrich Walter; Suzanne M Lohmann
Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I.
The Journal of biological chemistry 2000;275(33):25723-32.
2000: Karin Eizema; Henry Fechner; Karel Bezstarosti; S Schneider-Rasp; A van der Laarse; H Wang; Heinz-Peter Schultheiss; Wolfgang Poller; Jos M J Lamers
Adenovirus-based phospholamban antisense expression as a novel approach to improve cardiac contractile dysfunction: comparison of a constitutive viral versus an endothelin-1-responsive cardiac promoter.
Circulation 2000;101(18):2193-9.
1999: A Frey; S Schneider-Rasp; U Marienfeld; J C Yu; Martin Paul; Wolfgang Poller; Harald Schmidt
Biochemical and functional characterization of nitric oxide synthase III gene transfer using a replication-deficient adenoviral vector.
Biochemical pharmacology 1999;58(7):1155-66.
1999: A Haack; Wolfgang Poller; S Schneider-Rasp; P Thalheimer; C Schmitt; Peter Hanfland; Hans H Brackmann; Rainer Schwaab
Highly sensitive and species-specific assay for quantification of human transgene expression levels.
Haemophilia : the official journal of the World Federation of Hemophilia 1999;5(5):334-9.
1999: Henry Fechner; A Haack; H Wang; Xiaomin Wang; Karin Eizema; Matthias Pauschinger; R Schoemaker; R Veghel; A Houtsmuller; Heinz-Peter Schultheiss; Jos M J Lamers; Wolfgang Poller
Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers.
Gene therapy 1999;6(9):1520-35.
1999: U Marienfeld; A Haack; P Thalheimer; S Schneider-Rasp; Hans H Brackmann; Wolfgang Poller
'Autoreplication' of the vector genome in recombinant adenoviral vectors with different E1 region deletions and transgenes.
Gene therapy 1999;6(6):1101-13.
1999: Matthias Pauschinger; D Knopf; S Petschauer; A Doerner; Wolfgang Poller; Peter L Schwimmbeck; Uwe Kühl; Heinz-Peter Schultheiss
Dilated cardiomyopathy is associated with significant changes in collagen type I/III ratio.
Circulation 1999;99(21):2750-6.
1999: Wolfgang Poller; F Merklein; S Schneider-Rasp; A Haack; Henry Fechner; H Wang; I Anagnostopoulos; S Weidinger
Molecular characterisation of the defective alpha 1-antitrypsin alleles PI Mwurzburg (Pro369Ser), Mheerlen (Pro369Leu), and Q0lisbon (Thr68Ile).
European journal of human genetics : EJHG 1999;7(3):321-31.
1999: A Haack; C Schmitt; Wolfgang Poller; Johannes Oldenburg; Peter Hanfland; Hans H Brackmann; Rainer Schwaab
Analysis of expression kinetics and activity of a new B-domain truncated and full-length FVIII protein in three different cell lines.
Annals of hematology 1999;78(3):111-6.
1999: Matthias Pauschinger; M D Phan; A Doerner; Uwe Kuehl; Peter L Schwimmbeck; Wolfgang Poller; Reinhard Kandolf; Heinz-Peter Schultheiss
Enteroviral RNA replication in the myocardium of patients with left ventricular dysfunction and clinically suspected myocarditis.
Circulation 1999;99(7):889-95.
1998: Stepan Gambaryan; C Wagner; Albert Smolenski; U Walter; Wolfgang Poller; W Haase; A Kurtz; Suzanne M Lohmann
Endogenous or overexpressed cGMP-dependent protein kinases inhibit cAMP-dependent renin release from rat isolated perfused kidney, microdissected glomeruli, and isolated juxtaglomerular cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):9003-8.
1998: Michael Halank; M Wiemer; Carsten Tschöpe; Wolfgang Poller; Peter L Schwimmbeck; Dieter Horstkotte; Gert Höffken
[Precapillary pulmonary hypertension of uncertain etiology].
Deutsche medizinische Wochenschrift (1946) 1998;123(28-29):861-5.
1997: Arie B Vaandrager; Ben C Tilly; Albert Smolenski; S Schneider-Rasp; Alice G M Bot; Marcel Edixhoven; Bob J Scholte; Thomas Jarchau; Ulrich Walter; Suzanne M Lohmann; Wolfgang Poller; Hugo R de Jonge
cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta.
The Journal of biological chemistry 1997;272(7):4195-200.
1996: Wolfgang Poller; S Schneider-Rasp; U Liebert; F Merklein; P Thalheimer; A Haack; Rainer Schwaab; C Schmitt; Hans H Brackmann
Stabilization of transgene expression by incorporation of E3 region genes into an adenoviral factor IX vector and by transient anti-CD4 treatment of the host.
Gene therapy 1996;3(6):521-30.
1995: V N Kalinin; W Schmidt; Wolfgang Poller; K Olek
[A new point mutation in the mitochondrial gene ND1, detected in a patient with type II diabetes].
Genetika 1995;31(8):1180-2.
1995: J Hager; L Hansen; C Vaisse; Nathalie Vionnet; Anne Philippi; Wolfgang Poller; Gilberto Velho; Carlo Carcassi; L Contu; C Julier
A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus.
Nature genetics 1995;9(3):299-304.
1995: Wolfgang Poller; Thomas E Willnow; Jan Hilpert; Joachim Herz
Differential recognition of alpha 1-antitrypsin-elastase and alpha 1-antichymotrypsin-cathepsin G complexes by the low density lipoprotein receptor-related protein.
The Journal of biological chemistry 1995;270(6):2841-5.
1995: Wolfgang Poller
Application of molecular genetics to the study of beta-cell function and diabetes mellitus.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1995;103 Suppl 2():15-22.
1994: J P Faber; Wolfgang Poller; S Weidinger; M Kirchgesser; Rainer Schwaab; F Bidlingmaier; K Olek
Identification and DNA sequence analysis of 15 new alpha 1-antitrypsin variants, including two PI*Q0 alleles and one deficient PI*M allele.
American journal of human genetics 1994;55(6):1113-21.
1994: J Hager; Hélène Blanché; F Sun; N V Vaxillaire; Wolfgang Poller; D Cohen; P Czernichow; Gilberto Velho; Jean-Jacques Robert; N Cohen
Six mutations in the glucokinase gene identified in MODY by using a nonradioactive sensitive screening technique.
Diabetes 1994;43(5):730-3.
1993: Wolfgang Poller; J P Faber; S Weidinger; K Tief; S Scholz; M Fischer; K Olek; M Kirchgesser; Hans-Heinrich Heidtmann
A leucine-to-proline substitution causes a defective alpha 1-antichymotrypsin allele associated with familial obstructive lung disease.
Genomics 1993;17(3):740-3.
1993: J P Faber; Wolfgang Poller; K Olek; U Baumann; J Carlson; B Lindmark; S Eriksson
The molecular basis of alpha 1-antichymotrypsin deficiency in a heterozygote with liver and lung disease.
Journal of hepatology 1993;18(3):313-21.
1993: Wolfgang Poller; J P Faber
[Molecular analysis of pulmonary risk genes. Relevance for clinical research, diagnosis and therapy].
Medizinische Klinik (Munich, Germany : 1983) 1993;88(4):212-30.
1993: B Lüdecke; Wolfgang Poller; K Olek; K Bartholomé
Sequence variant of the human cathepsin G gene.
Human genetics 1993;91(1):83-4.
1993: Wolfgang Poller; Helmut Schatz
Molecular genetic analysis of NIDDM. Status and prospects.
Experimental and clinical endocrinology 1993;101(2):58-68.
1992: S Weidinger; Wolfgang Poller; J P Faber; F Schwarzfischer
Improved phenotyping of alpha 1-antichymotrypsin (ACT) by isoelectric focusing and immunoprinting: first demonstration of a deficient protein variant in the ACT system.
Electrophoresis 1992;13(9-10):778-80.
1992: Wolfgang Poller; J P Faber; S Scholz; S Weidinger; K Bartholomé; K Olek; S Eriksson
Mis-sense mutation of alpha 1-antichymotrypsin gene associated with chronic lung disease.
Lancet 1992;339(8808):1538.
1992: Wolfgang Poller; J P Faber; G Klobeck; K Olek
Cloning of the human alpha 2-macroglobulin gene and detection of mutations in two functional domains: the bait region and the thiolester site.
Human genetics 1992;88(3):313-9.
1991: Wolfgang Poller; J P Faber; S Scholz; K Olek; K M Müller
Sequence analysis of the cystic fibrosis gene in patients with disseminated bronchiectatic lung disease. Application in the identification of a cystic fibrosis patient with atypical clinical course.
Klinische Wochenschrift 1991;69(14):657-63.
1991: Wolfgang Poller; J P Faber; S Weidinger; K Olek
DNA polymorphisms associated with a new alpha 1-antitrypsin PIQ0 variant (PIQ0riedenburg).
Human genetics 1991;86(5):522-4.
1991: Wolfgang Poller; J P Faber; K Olek
Sequence polymorphism in the human alpha-2-macroglobulin (A2M) gene.
Nucleic acids research 1991;19(1):198.
1990: Wolfgang Poller; J P Faber; K Olek
Highly variable clinical course in severe alpha 1-antitrypsin deficiency--use of polymerase chain reaction for the detection of rare deficiency alleles.
Klinische Wochenschrift 1990;68(17):857-63.
1990: Wolfgang Poller; Abderrahman Machraoui; W T Ulmer
[Pulmonary gas exchange in conventional ventilation and high frequency ventilation in severe respiratory insufficiency].
Pneumologie (Stuttgart, Germany) 1990;44 Suppl 1():668-9.
1990: Wolfgang Poller; C Meisen; K Olek
DNA polymorphisms of the alpha 1-antitrypsin gene region in patients with chronic obstructive pulmonary disease.
European journal of clinical investigation 1990;20(1):1-7.
1990: Wolfgang Poller
[Genetic defects in pneumology].
Verhandlungen der Deutschen Gesellschaft für Innere Medizin 1990;96():441-50.
1989: Kurt Rasche; Wolfgang Poller; Annette Fisseler-Eckhoff; V Wiebe
[Mucoviscidosis: late diagnosis despite typical clinical features].
Deutsche medizinische Wochenschrift (1946) 1989;114(41):1566-70.
1989: Wolfgang Poller; J Barth; B Voss
Detection of an alteration of the alpha 2-macroglobulin gene in a patient with chronic lung disease and serum alpha 2-macroglobulin deficiency.
Human genetics 1989;83(1):93-6.
1989: Wolfgang Poller; C Meisen; K Olek
PstI polymorphism of the alpha 1-antitrypsin-like gene.
Nucleic acids research 1989;17(5):2151.
1989: Wolfgang Poller; J Barth; G Klobeck; W Ulmer
[DNA polymorphism of the alpha 2-macroglobulin gene in patients with chronic obstructive lung disease and serum alpha 2-macroglobulin deficiency].
Verhandlungen der Deutschen Gesellschaft für Innere Medizin 1989;95():7-12.
1988: C Meisen; Wolfgang Poller; K Olek
DNA haplotyping of PI Z and M alleles within the German population.
American journal of human genetics 1988;43(6):978-9.