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Jose Rueff

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Bernardo Brito Palma; Jose Rueff; Marta Silva E Sousa; Phillipe Urban; Michel Kranendonk
Functional characterization of eight human CYP1A2 variants: the role of cytochrome b5.
Marta Gromicho; António Laires; Marta Magalhães; Paula Rendeiro; Jose Rueff; Joana Dinis; Alexandra R Fernandes; Purificação Tavares; Fátima Torres; António Sebastião Rodrigues
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.
Luís S Santos; Susana N Silva; Ana Paula Azevedo; Sandra C Branco; Teresa Cruz Ferreira; Octávia Monteiro Gil; Edward Limbert; Isabel Manita; Jose Rueff; Jorge Gaspar
Polymorphisms in base excision repair genes and thyroid cancer risk.

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2013: Bernardo Brito Palma; Jose Rueff; Marta Silva E Sousa; Phillipe Urban; Michel Kranendonk
Functional characterization of eight human CYP1A2 variants: the role of cytochrome b5.
Pharmacogenetics and genomics 2013;23(2):41-52.
2013: Marta Gromicho; António Laires; Marta Magalhães; Paula Rendeiro; Jose Rueff; Joana Dinis; Alexandra R Fernandes; Purificação Tavares; Fátima Torres; António Sebastião Rodrigues
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.
Oncology reports 2013;29(2):741-50.
2012: Luís S Santos; Susana N Silva; Ana Paula Azevedo; Sandra C Branco; Teresa Cruz Ferreira; Octávia Monteiro Gil; Edward Limbert; Isabel Manita; Jose Rueff; Jorge Gaspar
Polymorphisms in base excision repair genes and thyroid cancer risk.
Oncology reports 2012;28(5):1859-68.
2012: Célia Martins; David H Phillips; Raquel Cação; Kathleen J Cole; António Laires; Jose Rueff; António S Rodrigues
Estragole: a weak direct-acting food-borne genotoxin and potential carcinogen.
Mutation research 2012;747(1):86-92.
2012: Antonio S Rodrigues; Joana Dinis; Marta Gromicho; António Laires; Celia Martins; Jose Rueff
Genomics and cancer drug resistance.
Current pharmaceutical biotechnology 2012;13(5):651-73.
2012: Susana N Silva; Ana Paula Azevedo; Guilherme Bezerra De Castro; Mafalda Gomes; Daniela Guerreiro; Jose Rueff; Jorge Gaspar
SNPs/pools: a methodology for the identification of relevant SNPs in breast cancer epidemiology.
Oncology reports 2012;27(2):511-6.
2011: Joaquim Calado; René Santer; Jose Rueff
Effect of kidney disease on glucose handling (including genetic defects).
Kidney international. Supplement 2011;(120):S7-13.
2011: Célia Martins; Carolina Doran; António Laires; Jose Rueff; António S Rodrigues
Genotoxic and apoptotic activities of the food flavourings myristicin and eugenol in AA8 and XRCC1 deficient EM9 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(2):385-92.
2010: B Brito Palma; M Silva E Sousa; C R Vosmeer; J Lastdrager; Jose Rueff; N P E Vermeulen; Michel Kranendonk
Functional characterization of eight human cytochrome P450 1A2 gene variants by recombinant protein expression.
The pharmacogenomics journal 2010;10(6):478-88.
2010: Bruno Costa Gomes; Susana N Silva; Ana Paula Azevedo; Isabel Manita; Octávia Monteiro Gil; Teresa Cruz Ferreira; Edward Limbert; Jose Rueff; Jorge Gaspar
The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk.
Oncology reports 2010;24(4):1079-85.
2010: Rafael Gómez-Bombarelli; Bernardo Brito Palma; Célia Martins; Michel Kranendonk; António S Rodrigues; Emilio Calle; Jose Rueff; Juan Casado
Alkylating potential of oxetanes.
Chemical research in toxicology 2010;23(7):1275-81.
2009: Helder Novais Bastos; Mónica Rego Antão; Susana N Silva; Ana Paula Azevedo; Isabel Manita; Valdemar Teixeira; Julieta Esperança Pina; Octávia Monteiro Gil; Teresa Cruz Ferreira; Edward Limbert; Jose Rueff; Jorge Gaspar
Association of polymorphisms in genes of the homologous recombination DNA repair pathway and thyroid cancer risk.
Thyroid : official journal of the American Thyroid Association 2009;19(10):1067-75.
2009: Susana N Silva; Ana Paula Azevedo; Valdemar Teixeira; Julieta Esperança Pina; Jose Rueff; Jorge Gaspar
The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.
Oncology reports 2009;22(3):593-8.
2009: João Conde; Susana N Silva; Ana Paula Azevedo; Valdemar Teixeira; Julieta Esperança Pina; Jose Rueff; Jorge Gaspar
Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study.
BMC cancer 2009;9():344.
2009: Jose Rueff; João P Teixeira; Luís Silva Santos; Jorge Gaspar
Genetic effects and biotoxicity monitoring of occupational styrene exposure.
Clinica chimica acta; international journal of clinical chemistry 2009;399(1-2):8-23.
2008: Ana M Neves; Gertrude Thompson; Júlio Carvalheira; José Costa Trindade; Jose Rueff; Joaquim Machado Caetano; James W Casey; Sylvie Hermouet
Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma.
Brain research 2008;1221():108-14.
2008: Michel Kranendonk; Christopher C Marohnic; Satya P Panda; Maria Paula Duarte; José Santos Oliveira; Bettie Sue Masters; Jose Rueff
Impairment of human CYP1A2-mediated xenobiotic metabolism by Antley-Bixler syndrome variants of cytochrome P450 oxidoreductase.
Archives of biochemistry and biophysics 2008;475(2):93-9.
2008: Joao Paulo Teixeira; Susana Silva; J Torres; Jorge Gaspar; J Roach; Peter B Farmer; Jose Rueff; Olga Mayan
Styrene-oxide N-terminal valine haemoglobin adducts as biomarkers of occupational exposure to styrene.
International journal of hygiene and environmental health 2008;211(1-2):59-62.
2008: A Brás; C Z Cotrim; I Vasconcelos; J Mexia; A Léonard; I Sanzhar; N Akhmatullina; Jose Rueff
Asynchronous DNA replication detected by fluorescence in situ hybridisation as a possible indicator of genetic damage in human lymphocytes.
Oncology reports 2008;19(2):369-75.
2007: Joao Paulo Teixeira; Jorge Gaspar; Joana Roma-Torres; Susana Silva; Carla Costa; J Roach; Olga Mayan; Jose Rueff; Peter B Farmer
Styrene-oxide N-terminal valine haemoglobin adducts in reinforced plastic workers: possible influence of genetic polymorphism of drug-metabolising enzymes.
Toxicology 2007;237(1-3):58-64.
2007: Ana S Fernandes; Jorge Gaspar; M Fátima Cabral; Cátia Caneiras; Rita Guedes; Jose Rueff; Matilde Castro; Judite Costa; Nuno G Oliveira
Macrocyclic copper(II) complexes: superoxide scavenging activity, structural studies and cytotoxicity evaluation.
Journal of inorganic biochemistry 2007;101(5):849-58.
2007: Célia Martins; Nuno G Oliveira; Marta Pingarilho; Gonçalo Gamboa da Costa; Vanda Martins; M Matilde Marques; Frederick A Beland; Mona I Churchwell; Daniel R Doerge; Jose Rueff; Jorge Gaspar
Cytogenetic damage induced by acrylamide and glycidamide in mammalian cells: correlation with specific glycidamide-DNA adducts.
Toxicological sciences : an official journal of the Society of Toxicology 2007;95(2):383-90.
2007: Susana N Silva; Rita Moita; Ana Paula Azevedo; Rita Gouveia; Isabel Manita; Julieta Esperança Pina; Jose Rueff; Jorge Gaspar
Menopausal age and XRCC1 gene polymorphisms: role in breast cancer risk.
Cancer detection and prevention 2007;31(4):303-9.
2007: Maria Paula Duarte; Bernardo Brito Palma; Maxim Chudaev; António Laires; José Santos Oliveira; Sergey A Usanov; Jose Rueff; Michel Kranendonk
The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93-100).
Mutagenesis 2007;22(1):75-81.
2007: Sandra Brum; Jose Rueff; João R Santos; Joaquim Calado
Unusual adult-onset manifestation of an attenuated Bartter's syndrome type IV renal phenotype caused by a mutation in BSND.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(1):288-9.
2006: Susana N Silva; Marisa N Cabral; Guilherme Bezerra de Castro; Marcelo Pires; Ana Paula Azevedo; Isabel Manita; Julieta Esperança Pina; Jose Rueff; Jorge Gaspar
Breast cancer risk and polymorphisms in genes involved in metabolism of estrogens (CYP17, HSD17beta1, COMT and MnSOD): possible protective role of MnSOD gene polymorphism Val/Ala and Ala/Ala in women that never breast fed.
Oncology reports 2006;16(4):781-8.
2006: Susana N Silva; Guilherme Bezerra de Castro; Ana Faber; Marcelo Pires; Vanessa C Oliveira; Ana Paula Azevedo; Marisa N Cabral; Isabel Manita; Julieta Esperança Pina; Jose Rueff; Jorge Gaspar
The role of ERCC2 polymorphisms in breast cancer risk.
Cancer genetics and cytogenetics 2006;170(1):86-8.
2006: Carla Costa; Joao Paulo Teixeira; Susana Silva; Joana Roma-Torres; Patrícia Coelho; Jorge Gaspar; Maria Alves; Blanca Laffon; Jose Rueff; Olga Mayan
Cytogenetic and molecular biomonitoring of a Portuguese population exposed to pesticides.
Mutagenesis 2006;21(5):343-50.
2006: Alexandra Maralhas; Ana Monteiro; Célia Martins; Michel Kranendonk; António Laires; Jose Rueff; António S Rodrigues
Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol.
Mutagenesis 2006;21(3):199-204.
2006: Joaquim Calado; J Loeffler; Onur Sakallioglu; Faysal Gok; K Lhotta; J Barata; Jose Rueff
Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting.
Kidney international 2006;69(5):852-5.
2006: Beatriz Porto; Ricardo Jorge Dinis Oliveira; Carla Sousa; Jorge Gaspar; Jose Rueff; Félix Carvalho; Isabel Malheiro
The role of foetal red blood cells in protecting cultured lymphocytes against diepoxybutane-induced chromosome breaks.
Mutation research 2006;603(1):41-7.
2005: Susana N Silva; Octávia Monteiro Gil; Vanessa C Oliveira; Marisa N Cabral; Ana Paula Azevedo; Ana Faber; Isabel Manita; Teresa Cruz Ferreira; Edward Limbert; Julieta Esperança Pina; Jose Rueff; Jorge Gaspar
Association of polymorphisms in ERCC2 gene with non-familial thyroid cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(10):2407-12.
2005: Margarida Goulart de Medeiros; M C Batoréu; António S Rodrigues; António Laires; Jose Rueff
Lipoperoxidation products and thiol antioxidants in chromium exposed workers.
Mutagenesis 2005;20(5):311-5.
2005: Nuno G Oliveira; Matilde Castro; António S Rodrigues; Isabel C Gonçalves; Célia Martins; José M Toscano-Rico; Jose Rueff
Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the boron neutron capture reaction.
Mutation research 2005;583(1):36-48.
2005: Maria Paula Duarte; Bernardo Brito Palma; António Laires; José Santos Oliveira; Jose Rueff; Michel Kranendonk
Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.
Mutagenesis 2005;20(3):199-208.
2005: Maria Paula Duarte; Bernardo Brito Palma; Maxim Chudaev; António Laires; José Santos Oliveira; Sergey A Usanov; Jose Rueff; Michel Kranendonk
The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
Mutagenesis 2005;20(2):93-100.
2005: Ana Faber; Guilherme N M Ferreira; Susana N Silva; Jose Rueff; Jorge Gaspar
Multiplex PCR-single-base extension genotyping of multiple glutathione S-transferase polymorphisms.
Biotechnology and applied biochemistry 2005;41(Pt 1):9-15.
2005: Joaquim Calado; Augusta Gaspar; Carla Clemente; Jose Rueff
A novel heterozygous missense mutation in the UMOD gene responsible for Familial Juvenile Hyperuricemic Nephropathy.
BMC medical genetics 2005;6():5.
2005: António S Rodrigues; Nuno G Oliveira; Octávia Monteiro Gil; A Léonard; Jose Rueff
Use of cytogenetic indicators in radiobiology.
Radiation protection dosimetry 2005;115(1-4):455-60.
2005: A Léonard; Jose Rueff; GB Gerber; ED Léonard
Usefulness and limits of biological dosimetry based on cytogenetic methods.
Radiation protection dosimetry 2005;115(1-4):448-54.
2004: Joaquim Calado; K Soto; Carla Clemente; P Correia; Jose Rueff
Gene Symbol: SLC55A2. Disease: familial renal glucosuria.
Human genetics 2004;115(2):170.
2004: Jorge Gaspar; Sónia Rodrigues; Octávia Monteiro Gil; Isabel Manita; Teresa Cruz Ferreira; Edward Limbert; Luzia Gonçalves; Julieta Esperança Pina; Jose Rueff
Combined effects of glutathione S-transferase polymorphisms and thyroid cancer risk.
Cancer genetics and cytogenetics 2004;151(1):60-7.
2004: Joao Paulo Teixeira; Jorge Gaspar; Susana Silva; Joana Torres; Susana N Silva; M Conceição Azevedo; Paula Neves; Blanca Laffon; Josefina Méndez; Carla Gonçalves; Olga Mayan; Peter B Farmer; Jose Rueff
Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1.
Toxicology 2004;195(2-3):231-42.
2004: Joaquim Calado; Karina Soto; Carla Clemente; Pedro Correia; Jose Rueff
Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria.
Human genetics 2004;114(3):314-6.
2004: Maria do Céu Silva; Jorge Gaspar; Isabel Duarte Silva; Ana Faber; Jose Rueff
GSTM1, GSTT1, and GSTP1 genotypes and the genotoxicity of hydroquinone in human lymphocytes.
Environmental and molecular mutagenesis 2004;43(4):258-64.
2003: Maria do Céu Silva; Jorge Gaspar; Isabel Duarte Silva; Daniela Leão; Jose Rueff
Mechanisms of induction of chromosomal aberrations by hydroquinone in V79 cells.
Mutagenesis 2003;18(6):491-6.
2003: Maria do Céu Silva; Jorge Gaspar; Isabel Duarte Silva; Daniela Leão; Jose Rueff
Induction of chromosomal aberrations by phenolic compounds: possible role of reactive oxygen species.
Mutation research 2003;540(1):29-42.
2003: Beatriz Porto; Laura Chiecchio; Jorge Gaspar; Ana Faber; Luciana Pinho; Jose Rueff; Isabel Malheiro
Role of haemoglobin in the protection of cultured lymphocytes against diepoxybutane (DEB), assessed by in vitro induced chromosome breakage.
Mutation research 2003;536(1-2):61-7.
2003: Bárbara Gigante; C Santos; Artur M S Silva; Maria João Marcelo Curto; Maria São José Nascimento; E Pinto; Madalena Pedro; Fátima Cerqueira; Madalena M M Pinto; Maria Paula Duarte; António Laires; Jose Rueff; J Gonçalves; M I Pegado; M L Valdeira
Catechols from abietic acid synthesis and evaluation as bioactive compounds.
Bioorganic & medicinal chemistry 2003;11(8):1631-8.
2003: Nuno G Oliveira; Matilde Castro; António S Rodrigues; I C Concalves; Octávia Monteiro Gil; AP Fernandes; José M Toscano-Rico; Jose Rueff
Wortmannin enhances the induction of micronuclei by low and high LET radiation.
Mutagenesis 2003;18(2):217.
2003: Nuno G Oliveira; Matilde Castro; António S Rodrigues; Isabel C Gonçalves; Octávia Monteiro Gil; AP Fernandes; José M Toscano-Rico; Jose Rueff
Wortmannin enhances the induction of micronuclei by low and high LET radiation.
Mutagenesis 2003;18(1):37-44.
2003: M G Medeiros; António S Rodrigues; M C Batoréu; António Laires; Jose Rueff; A Zhitkovich
Elevated levels of DNA-protein crosslinks and micronuclei in peripheral lymphocytes of tannery workers exposed to trivalent chromium.
Mutagenesis 2003;18(1):19-24.
2002: Octávia Monteiro Gil; Nuno G Oliveira; António S Rodrigues; António Laires; Teresa Cruz Ferreira; Edward Limbert; Jose Rueff
Possible transient adaptive response to mitomycin C in peripheral lymphocytes from thyroid cancer patients after iodine-131 therapy.
International journal of cancer. Journal international du cancer 2002;102(6):556-61.
2002: Jose Rueff; Jorge Gaspar; Michel Kranendonk
DNA polymorphisms as modulators of genotoxicity and cancer.
Biological chemistry 2002;383(6):923-32.
2002: Joao Paulo Teixeira; Jorge Gaspar; Gabriela Martinho; Susana Silva; Sónia Rodrigues; Olga Mayan; Elizabeth Martin; Peter B Farmer; Jose Rueff
Aromatic DNA adduct levels in coke oven workers: correlation with polymorphisms in genes GSTP1, GSTM1, GSTT1 and CYP1A1.
Mutation research 2002;517(1-2):147-55.
2002: S Marques; Nuno G Oliveira; T Chaveca; Jose Rueff
Micronuclei and sister chromatid exchanges induced by capsaicin in human lymphocytes.
Mutation research 2002;517(1-2):39-46.
2002: Nuno G Oliveira; Matilde Castro; António S Rodrigues; Octávia Monteiro Gil; José M Toscano-Rico; Jose Rueff
DNA-PK inhibitor wortmannin enhances DNA damage induced by bleomycin in V79 Chinese hamster cells.
Teratogenesis, carcinogenesis, and mutagenesis 2002;22(5):343-51.
2001: Nuno G Oliveira; Matilde Castro; António S Rodrigues; Isabel C Gonçalves; R Cassapo; AP Fernandes; T Chaveca; José M Toscano-Rico; Jose Rueff
Evaluation of the genotoxic effects of the boron neutron capture reaction in human melanoma cells using the cytokinesis block micronucleus assay.
Mutagenesis 2001;16(5):369-75.
2001: H Caria; T Chaveca; Jose Rueff
Aneuploidy induced in lymphocytes of parents of trisomic 21 children.
Teratogenesis, carcinogenesis, and mutagenesis 2001;21(5):369-82.
2000: Octávia Monteiro Gil; Nuno G Oliveira; António S Rodrigues; António Laires; Teresa Cruz Ferreira; Edward Limbert; Jose Rueff
No evidence of increased chromosomal aberrations and micronuclei in lymphocytes from nonfamilial thyroid cancer patients prior to radiotherapy.
Cancer genetics and cytogenetics 2000;123(1):55-60.
2000: Michel Kranendonk; António Laires; Jose Rueff; W R Estabrook; Nico P E Vermeulen
Heterologous expression of xenobiotic mammalian-metabolizing enzymes in mutagenicity tester bacteria: an update and practical considerations.
Critical reviews in toxicology 2000;30(3):287-306.
2000: I Alves; Nuno G Oliveira; António Laires; António S Rodrigues; Jose Rueff
Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: role of ascorbic acid as a modulator of patulin clastogenicity.
Mutagenesis 2000;15(3):229-34.
2000: Isabel Duarte Silva; Jorge Gaspar; G G da Costa; António S Rodrigues; António Laires; Jose Rueff
Chemical features of flavonols affecting their genotoxicity. Potential implications in their use as therapeutical agents.
Chemico-biological interactions 2000;124(1):29-51.
2000: Maria Paula Duarte; António Laires; Jorge Gaspar; José Santos Oliveira; Jose Rueff
Genotoxicity of instant coffee and of some phenolic compounds present in coffee upon nitrosation.
Teratogenesis, carcinogenesis, and mutagenesis 2000;20(4):241-9.
2000: Nuno G Oliveira; M Neves; António S Rodrigues; Octávia Monteiro Gil; T Chaveca; Jose Rueff
Assessment of the adaptive response induced by quercetin using the MNCB peripheral blood human lymphocytes assay.
Mutagenesis 2000;15(1):77-83.
2000: Octávia Monteiro Gil; Nuno G Oliveira; António S Rodrigues; António Laires; Teresa Cruz Ferreira; Edward Limbert; A Léonard; G Gerber; Jose Rueff
Cytogenetic alterations and oxidative stress in thyroid cancer patients after iodine-131 therapy.
Mutagenesis 2000;15(1):69-75.
1999: Maria Paula Duarte; António Laires; Jorge Gaspar; Daniela Leão; José Santos Oliveira; Jose Rueff
Genotoxicity of instant coffee: possible involvement of phenolic compounds.
Mutation research 1999;442(1):43-51.
1999: L A Marcelino; M Galvin; G M Martins; M J Proença; E Mayrand; Jose Rueff; C J Monteiro
Fast and reliable screening of mutations in human tumors: use of multiple fluorescence-based long linker arm nucleotides assay (mf-LLA).
BioTechniques 1999;26(6):1134-8, 1140-2, 1144 passim.
1999: A Léonard; GB Gerber; C Stecca; Jose Rueff; H Borba; P B Farmer; Radim J Sram; A E Czeizel; Ivan Kalina
Mutagenicity, carcinogenicity, and teratogenicity of acrylonitrile.
Mutation research 1999;436(3):263-83.
1999: Michel Kranendonk; Filipa Carreira Barbosa; P Theisen; António Laires; Charles W Fisher; Jose Rueff; Ronald W Estabrook; Nico P E Vermeulen
Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies.
Mutation research 1999;441(1):73-83.
1999: Michel Kranendonk; Charles W Fisher; R Roda; Filipa Carreira Barbosa; P Theisen; António Laires; Jose Rueff; Nico P E Vermeulen; Ronald W Estabrook
Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: comparison of three types of expression systems.
Mutation research 1999;439(2):287-300.
1998: Michel Kranendonk; P Mesquita; António Laires; Nico P E Vermeulen; Jose Rueff
Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.
Mutagenesis 1998;13(3):263-9.
1997: Nuno G Oliveira; António S Rodrigues; T Chaveca; Jose Rueff
Induction of an adaptive response to quercetin, mitomycin C and hydrogen peroxide by low doses of quercetin in V79 Chinese hamster cells.
Mutagenesis 1997;12(6):457-62.
1997: Isabel Duarte Silva; António S Rodrigues; Jorge Gaspar; António Laires; Jose Rueff
Metabolism of galangin by rat cytochromes P450: relevance to the genotoxicity of galangin.
Mutation research 1997;393(3):247-57.
1997: Isabel Duarte Silva; António S Rodrigues; Jorge Gaspar; R Maia; António Laires; Jose Rueff
Involvement of rat cytochrome 1A1 in the biotransformation of kaempferol to quercetin: relevance to the genotoxicity of kaempferol.
Mutagenesis 1997;12(5):383-90.
1997: H Caria; A Quintas; T Chaveca; Jose Rueff
The role of poly(ADP-ribose)polymerase in the induction of sister chromatid exchanges and micronuclei by mitomycin C in Down's syndrome cells as compared to euploid cells.
Mutation research 1997;377(2):269-77.
1997: Michel Kranendonk; Jan N M Commandeur; António Laires; Jose Rueff; Nico P E Vermeulen
Characterization of enzyme activities and cofactors involved in bioactivation and bioinactivation of chemical carcinogens in the tester strains Escherichia coli K12 MX100 and Salmonella typhimurium LT2 TA100.
Mutagenesis 1997;12(4):245-54.
1996: R Almeida; N Morton; P Fidalgo; N Leitão; C Mira; Jose Rueff; C Monteiro
APC intragenic haplotypes in familial adenomatous polyposis.
Clinical genetics 1996;50(6):483-5.
1996: R Tavares; H Borba; M Monteiro; M J Proença; N Lynce; Jose Rueff; E Bailey; G M Sweetman; R M Lawrence; Peter B Farmer
Monitoring of exposure to acrylonitrile by determination of N-(2-cyanoethyl)valine at the N-terminal position of haemoglobin.
Carcinogenesis 1996;17(12):2655-60.
1996: Michel Kranendonk; F Pintado; P Mesquita; António Laires; Nico P E Vermeulen; Jose Rueff
MX100, a new Escherichia coli tester strain for use in genotoxicity studies.
Mutagenesis 1996;11(4):327-33.
1996: Jose Rueff; C Chiapella; J K Chipman; F Darroudi; Isabel Duarte Silva; M Duverger-van Bogaert; E Fonti; H R Glatt; P Isern; António Laires; A Léonard; M Llagostera; P Mossesso; A T Natarajan; Fabrizio Palitti; António S Rodrigues; A Schinoppi; G Turchi; G Werle-Schneider
Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays.
Mutation research 1996;353(1-2):151-76.
1996: R Almeida; P Fidalgo; E Ramalho; A Brás; N Leitão; C Mira; Jose Rueff; C Monteiro
Presymptomatic diagnosis in Portuguese FAP families using intragenic RFLPs and (CA)n flanking markers by fluorescence based semiautomated DNA analysis.
Journal of medical genetics 1996;33(3):244-7.
1996: Isabel Duarte Silva; A Rodrigues; Jorge Gaspar; R Maia; António Laires; Jose Rueff
Mutagenicity of kaempferol in V79 cells: the role of cytochromes P450.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(4):229-41.
1996: L Cristóvão; Jose Rueff
Effect of a poly(ADP-ribose) polymerase inhibitor on DNA breakage and cytotoxicity induced by hydrogen peroxide and gamma-radiation.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(4):219-27.
1996: H Borba; M Monteiro; M J Proença; T Chaveca; V Pereira; N Lynce; Jose Rueff
Evaluation of some biomonitoring markers in occupationally exposed populations to acrylonitrile.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(4):205-18.
1996: Jorge Gaspar; António Laires; S Va; S Pereira; A Mariano; M Quina; Jose Rueff
Mutagenic activity of glycine upon nitrosation in the presence of chloride and human gastric juice: a possible role in gastric carcinogenesis.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(5):275-86.
1996: A Moreira; G Martins; M J Monteiro; M Alves; J Dias; J D da Costa; M J Melo; D Matias; A Costa; M Cristóvão; Jose Rueff; C Monteiro
Glutathione S-transferase mu polymorphism and susceptibility to lung cancer in the Portuguese population.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(5):269-74.
1996: Isabel Duarte Silva; Jorge Gaspar; A Rodrigues; G G da Costa; António Laires; Jose Rueff
Mechanisms of myricetin mutagenicity in V79 cells: involvement of radicalar species.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(5):253-68.
1996: H Caria; T Chaveca; Jose Rueff
Preferential sensitivity of acrocentric chromosomes to the aneugenic effect of colchicine.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(5):243-52.
1995: Jose Rueff; Jorge Gaspar; António Laires
Structural requirements for mutagenicity of flavonoids upon nitrosation. A structure-activity study.
Mutagenesis 1995;10(4):325-8.
1995: H Caria; T Chaveca; António Laires; Jose Rueff
Genotoxicity of quercetin in the micronucleus assay in mouse bone marrow erythrocytes, human lymphocytes, V79 cell line and identification of kinetochore-containing (CREST staining) micronuclei in human lymphocytes.
Mutation research 1995;343(2-3):85-94.
1995: A Brás; L Cristóvão; C Coelho; A Hilali; Bernard Dutrillaux; A Léonard; Jose Rueff
Normal genetic response to gamma irradiation in familial adenomatous polyposis.
European journal of cancer (Oxford, England : 1990) 1995;31A(9):1506-10.
1994: Jorge Gaspar; António Laires; Jose Rueff
Genotoxic flavonoids and red wine: a possible role in stomach carcinogenesis.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1994;3 Suppl 2():13-7.
1994: António S Rodrigues; Isabel Duarte Silva; M H Caria; António Laires; T Chaveca; H R Glatt; Jose Rueff
Genotoxicity assessment of aromatic amines and amides in genetically engineered V79 cells.
Mutation research 1994;341(2):93-100.
1994: Jorge Gaspar; A Rodrigues; António Laires; F Silva; S Costa; M J Monteiro; C Monteiro; Jose Rueff
On the mechanisms of genotoxicity and metabolism of quercetin.
Mutagenesis 1994;9(5):445-9.
1994: R Tavares; P Ramos; José Martins Palminha; MA Bispo; I Paz; A Bras; Jose Rueff; Peter B Farmer; E Bailey
Transplacental exposure to genotoxins. Evaluation in haemoglobin of hydroxyethylvaline adduct levels in smoking and non-smoking mothers and their newborns.
Carcinogenesis 1994;15(6):1271-4.
1994: Michel Kranendonk; M Ruas; António Laires; Jose Rueff
Isolation and prevalidation of an Escherichia coli tester strain for the use in mechanistic and metabolic studies of genotoxins.
Mutation research 1994;312(2):99-109.
1993: António Laires; Jorge Gaspar; H Borba; M Proença; M Monteiro; Jose Rueff
Genotoxicity of nitrosated red wine and of the nitrosatable phenolic compounds present in wine: tyramine, quercetin and malvidine-3-glucoside.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1993;31(12):989-94.
1993: Jose Rueff; A Brás; L Cristóvão; J Mexia; M Sá da Costa; V Pires
DNA strand breaks and chromosomal aberrations induced by H2O2 and 60Co gamma-radiation.
Mutation research 1993;289(2):197-204.
1993: Jorge Gaspar; António Laires; M Monteiro; O Laureano; E Ramos; Jose Rueff
Quercetin and the mutagenicity of wines.
Mutagenesis 1993;8(1):51-5.
1992: Jose Rueff; A Rodrigues; António Laires; Jorge Gaspar
Activation of promutagens by porphyrinic biomimetic systems.
Mutation research 1992;269(2):243-50.
1992: Jose Rueff; António Laires; Jorge Gaspar; H Borba; A Rodrigues
Oxygen species and the genotoxicity of quercetin.
Mutation research 1992;265(1):75-81.
1990: Jose Rueff; António Laires; Jorge Gaspar; A Rodrigues
Mutagenic activity in the wine-making process: correlations with rutin and quercetin levels.
Mutagenesis 1990;5(4):393-6.
1989: A Brás; C Monteiro; Jose Rueff
Oxidative stress in trisomy 21. A possible role in cataractogenesis.
Ophthalmic paediatrics and genetics 1989;10(4):271-7.
1989: António Laires; P Pacheco; Jose Rueff
Mutagenicity of rutin and the glycosidic activity of cultured cell-free microbial preparations of human faeces and saliva.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1989;27(7):437-43.
1989: C Monteiro; Jose Rueff; A B Falcao; S Portugal; D J Weatherall; A E Kulozik
The frequency and origin of the sickle cell mutation in the district of Coruche/Portugal.
Human genetics 1989;82(3):255-8.
1987: M Llagostera; S Garrido; Jordi Barbé; Ricardo Guerrero; Jose Rueff
Influence of S9 mix in the induction of SOS system by quercetin.
Mutation research 1987;191(1):1-4.
1986: Jose Rueff; António Laires; H Borba; T Chaveca; M I Gomes; M Halpern
Genetic toxicology of flavonoids: the role of metabolic conditions in the induction of reverse mutation, SOS functions and sister-chromatid exchanges.
Mutagenesis 1986;1(3):179-83.
1982: M I Gomes; Jose Rueff; M Halpern
VLDL-associated mutagenic activity.
British journal of cancer 1982;45(4):646-7.
1982: Jose Rueff; António Laires; M I Gomes; H Borba; J Magalhães; M Halpern
Mutagenicity in urine of workers in naval industry.
Progress in clinical and biological research 1982;109():443-52.
1982: António Laires; H Borba; Jose Rueff; M I Gomes; M Halpern
Urinary mutagenicity in occupational exposure to mineral oils and iron oxide particles.
Carcinogenesis 1982;3(9):1077-9.