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John Calam

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Ian L P Beales; John Calam
Regulation of amylin release from cultured rabbit gastric fundic mucosal cells.
Naila Arebi; Zoe V Healey; Philip W Bliss; Mohammad A Ghatei; Susan Van Noorden; Raymond J Playford; John Calam
Nitric oxide regulates the release of somatostatin from cultured gastric rabbit primary D-cells.
Houman Ashrafian; Simon D Taylor-Robinson; John Calam; Raymond J Playford
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All Publications

2003: Ian L P Beales; John Calam
Regulation of amylin release from cultured rabbit gastric fundic mucosal cells.
BMC physiology 2003;3():13.
2002: Naila Arebi; Zoe V Healey; Philip W Bliss; Mohammad A Ghatei; Susan Van Noorden; Raymond J Playford; John Calam
Nitric oxide regulates the release of somatostatin from cultured gastric rabbit primary D-cells.
Gastroenterology 2002;123(2):566-76.
2002: Houman Ashrafian; Simon D Taylor-Robinson; John Calam; Raymond J Playford
Once you start, you can't stop.
Lancet 2002;359(9302):226.
2001: Anthony J FitzGerald; M Jordinson; Jonathan M Rhodes; R Singh; John Calam; Robert A Goodlad
Comparison of the effects of concanavalin-A and epidermal growth factor on epithelial cell proliferation in the rat intestine.
Alimentary pharmacology & therapeutics 2001;15(7):1077-84.
2001: Pius Hildebrand; F S Lehmann; S Ketterer; A D Christ; T Stingelin; J Beltinger; A H Gibbons; D H Coy; John Calam; F Larsen; Christoph Beglinger
Regulation of gastric function by endogenous gastrin releasing peptide in humans: studies with a specific gastrin releasing peptide receptor antagonist.
Gut 2001;49(1):23-8.
2001: Ian L P Beales; John Calam
Inhibition of carbachol stimulated acid secretion by interleukin 1beta in rabbit parietal cells requires protein kinase C.
Gut 2001;48(6):782-9.
2001: kenneth simpson; Dalit Strauss-Ayali; Reinhard Straubinger; Eugenio Scanziani; Patrick L McDonough; AF Straubinger; Yung-Fu Chang; M I Esteves; J G Fox; C Domeneghini; Naila Arebi; John Calam
Helicobacter pylori infection in the cat: evaluation of gastric colonization, inflammation and function.
Helicobacter 2001;6(1):1-14.
2001: Damian M Bailey; Bruce Davies; Linda M Castell; Eric A Newsholme; John Calam
Physical exercise and normobaric hypoxia: independent modulators of peripheral cholecystokinin metabolism in man.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;90(1):105-13.
2000: S Murray; G W Taylor; Q N Karim; Philip W Bliss; John Calam
N alpha-methylhistamine: association with Helicobacter pylori infection in humans and effects on gastric acid secretion.
Clinica chimica acta; international journal of clinical chemistry 2000;301(1-2):181-92.
2000: Ian L P Beales; John Calam
Helicobacter pylori increases gastrin release from cultured canine antral G-cells.
European journal of gastroenterology & hepatology 2000;12(6):641-4.
2000: M Jordinson; Anthony J FitzGerald; Robert A Goodlad; AE Brynes; G Grant; Massimo Pignatelli; John Calam
Systemic effect of peanut agglutinin following intravenous infusion into rats.
Alimentary pharmacology & therapeutics 2000;14(6):835-40.
2000: Stephen Murray; Philip W Bliss; N Karim; John Calam; Graham W Taylor
Analysis of N(alpha)-methylhistamine by gas chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 2000;739(2):337-44.
2000: kenneth simpson; Dalit Strauss-Ayali; Eugenio Scanziani; Reinhard Straubinger; Patrick L McDonough; AF Straubinger; Yung-Fu Chang; C Domeneghini; Naila Arebi; John Calam
Helicobacter felis infection is associated with lymphoid follicular hyperplasia and mild gastritis but normal gastric secretory function in cats.
Infection and immunity 2000;68(2):779-90.
2000: Damian M Bailey; Bruce Davies; James S Milledge; M Richards; S R Williams; M Jordinson; John Calam
Elevated plasma cholecystokinin at high altitude: metabolic implications for the anorexia of acute mountain sickness.
High altitude medicine & biology 2000;1(1):9-23.
1999: Philip W Bliss; Zoe V Healey; Naila Arebi; John Calam
Nalpha-methyl histamine and histamine stimulate gastrin release from rabbit G-cells via histamine H2-receptors.
Alimentary pharmacology & therapeutics 1999;13(12):1669-74.
1999: M Jordinson; Robert A Goodlad; AE Brynes; Philip W Bliss; Mohammad A Ghatei; Stephen R Bloom; A Fitzgerald; G Grant; Susan Bardocz; Arpad Pusztai; Massimo Pignatelli; John Calam
Gastrointestinal responses to a panel of lectins in rats maintained on total parenteral nutrition.
The American journal of physiology 1999;276(5 Pt 1):G1235-42.
1999: M Jordinson; I el-Hariry; D Calnan; John Calam; Massimo Pignatelli
Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells.
Gut 1999;44(5):709-14.
1998: M Jordinson; John Calam; Massimo Pignatelli
Lectins: from basic science to clinical application in cancer prevention.
Expert opinion on investigational drugs 1998;7(9):1389-403.
1998: Ian L P Beales; John Calam
The histamine H3 receptor agonist N alpha-methylhistamine produced by Helicobacter pylori does not alter somatostatin release from cultured rabbit fundic D-cells.
Gut 1998;43(2):176-81.
1998: S G R G Barton; Vivienne R Winrow; David S Rampton; J E Crabtree; Ian L P Beales; John Calam
Circulating antibodies to the 60-kD heat shock protein (hsp) family in patients with Helicobacter pylori infection.
Clinical and experimental immunology 1998;112(3):490-4.
1998: I L Beales; John Calam
Pathogenic mechanisms in Helicobacter pylori infection.
Hospital medicine (London, England : 1998) 1998;59(3):186-90.
1998: Ian L P Beales; John Calam
Interleukin 1 beta and tumour necrosis factor alpha inhibit acid secretion in cultured rabbit parietal cells by multiple pathways.
Gut 1998;42(2):227-34.
1998: M Jordinson; Ian L P Beales; John Calam
Soybean agglutinin stimulated cholecystokinin release from cultured rabbit jejunal cells requires calcium influx via L-type calcium channels.
Peptides 1998;19(9):1541-7.
1998: Zoe V Healey; Philip W Bliss; J Edwards; Naila Arebi; Ian L P Beales; John Calam
Effect of PACAP-27 on 14C-aminopyrine accumulation in isolated rabbit parietal cells.
Peptides 1998;19(6):1111-4.
1998: John Calam
Clinical science of Helicobacter pylori infection: ulcers and NSAIDs.
British medical bulletin 1998;54(1):55-62.
1997: John Calam; A Gibbons; Zoe V Healey; Philip W Bliss; Naila Arebi
How does Helicobacter pylori cause mucosal damage? Its effect on acid and gastrin physiology.
Gastroenterology 1997;113(6 Suppl):S43-9; discussion S50.
1997: M Jordinson; R J Playford; John Calam
Effects of a panel of dietary lectins on cholecystokinin release in rats.
The American journal of physiology 1997;273(4 Pt 1):G946-50.
1997: Ian L P Beales; John Calam
Helicobacter pylori infection and tumour necrosis factor-alpha increase gastrin release from human gastric antral fragments.
European journal of gastroenterology & hepatology 1997;9(8):773-7.
1997: Ian L P Beales; Martin Blaser; S Srinivasan; John Calam; G I Pérez-Pérez; T Yamada; James M Scheiman; L Post; John Del Valle
Effect of Helicobacter pylori products and recombinant cytokines on gastrin release from cultured canine G cells.
Gastroenterology 1997;113(2):465-71.
1997: Zoe V Healey; John Calam
Inhibiting acid and Helicobacter pylori?
Gut 1997;41(1):125-6.
1997: Ian L P Beales; John Calam
Stimulation of IL-8 production in human gastric epithelial cells by Helicobacter pylori, IL-1beta and TNF-alpha requires tyrosine kinase activity, but not protein kinase C.
Cytokine 1997;9(7):514-20.
1997: A H Gibbons; Stephen Legon; Marjorie M Walker; Mohammad A Ghatei; John Calam
The effect of gastrin-releasing peptide on gastrin and somatostatin messenger RNAs in humans infected with Helicobacter pylori.
Gastroenterology 1997;112(6):1940-7.
1997: Ian L P Beales; John Calam
Helicobacter pylori stimulates granulocyte-macrophage colony-stimulating factor (GM-CSF) production from cultured antral biopsies and a human gastric epithelial cell line.
European journal of gastroenterology & hepatology 1997;9(5):451-5.
1997: A Weir; S D Taylor-Robinson; S Poole; M Pignatelli; J F Walters; John Calam
Cytoplasmic antineutrophil cytoplasmic antibody-positive vasculitis associated with ulcerative colitis.
The American journal of gastroenterology 1997;92(3):506-8.
1997: Ian L P Beales; John Calam
Effect of N alpha-methyl-histamine on acid secretion in isolated cultured rabbit parietal cells: implications for Helicobacter pylori associated gastritis and gastric physiology.
Gut 1997;40(1):14-9.
1997: Ian L P Beales; John Calam; L Post; S Srinivasan; T Yamada; John Del Valle
Effect of transforming growth factor alpha and interleukin 8 on somatostatin release from canine fundic D cells.
Gastroenterology 1997;112(1):136-43.
1996: Ian L P Beales; John Calam
Truncated glucagon-like peptide-1 and oxyntomodulin stimulate somatostatin release from rabbit fundic D-cells in primary culture.
Experimental physiology 1996;81(6):1039-41.
1996: Ian L P Beales; L Post; John Calam; Tadataka Yamada; John Del Valle
Tumour necrosis factor alpha stimulates gastrin release from canine and human antral G cells: possible mechanism of the Helicobacter pylori-gastrin link.
European journal of clinical investigation 1996;26(7):609-11.
1996: Ian L P Beales; J E Crabtree; D Scunes; A Covacci; John Calam
Antibodies to CagA protein are associated with gastric atrophy in Helicobacter pylori infection.
European journal of gastroenterology & hepatology 1996;8(7):645-9.
1996: M Jordinson; P H Deprez; Raymond J Playford; S Heal; T C Freeman; Stuart McDonald; John Calam
Soybean lectin stimulates pancreatic exocrine secretion via CCK-A receptors in rats.
The American journal of physiology 1996;270(4 Pt 1):G653-9.
1996: John Calam
Helicobacter pylori and hormones.
The Yale journal of biology and medicine 1996;69(1):39-49.
1995: John Calam
The somatostatin-gastrin link of Helicobacter pylori infection.
Annals of medicine 1995;27(5):569-73.
1995: John Calam
Pathogenic mechanisms.
Baillière's clinical gastroenterology 1995;9(3):487-506.
1995: Raymond J Playford; S Mehta; P Upton; R Rentch; S Moss; John Calam; Stephen R Bloom; N Payne; Mohammad A Ghatei; R Edwards
Effect of peptide YY on human renal function.
The American journal of physiology 1995;268(4 Pt 2):F754-9.
1995: John Calam
Helicobacter pylori, acid and gastrin.
European journal of gastroenterology & hepatology 1995;7(4):310-7.
1995: Raymond J Playford; A M Hanby; K Patel; John Calam
Influence of inflammatory bowel disease on the distribution and concentration of pancreatic secretory trypsin inhibitor within the colon.
The American journal of pathology 1995;146(2):310-6.
1995: Raymond J Playford; Tania Marchbank; DP Calnan; John Calam; P Royston; J J Batten; H F Hansen
Epidermal growth factor is digested to smaller, less active forms in acidic gastric juice.
Gastroenterology 1995;108(1):92-101.
1994: S F Moss; Stephen Legon; J Davies; John Calam
Cytokine gene expression in Helicobacter pylori associated antral gastritis.
Gut 1994;35(11):1567-70.
1994: John Calam
Helicobacter pylori.
European journal of clinical investigation 1994;24(8):501-10.
1994: A H Gibbons; John Calam
Cholecystokinin as a physiological regulator of gastric acid secretion in man.
European journal of clinical investigation 1994;24(6):367-9.
1994: Raymond J Playford; A M Hanby; C Quinn; John Calam
Influence of inflammation and atrophy on pancreatic secretory trypsin inhibitor levels within the gastric mucosa.
Gastroenterology 1994;106(3):735-41.
1994: S F Moss; Stephen Legon; John Calam
Reciprocal changes in antral gastrin and somatostatin mRNA in pernicious anemia.
Digestive diseases and sciences 1994;39(2):321-6.
1993: Raymond J Playford; A W King; P H Deprez; J De-Belleroche; T C Freeman; John Calam
Effects of diet and the cholecystokinin antagonist; devazepide (L364,718) on CCK mRNA, and tissue and plasma CCK concentrations.
European journal of clinical investigation 1993;23(10):641-7.
1993: S F Moss; A Waheed; K Beardshall; J Gill; D Adamson; R Unwin; John Calam
Use of endoscopic biopsies and microelectrodes to study human gastric acid secretion in vitro.
Neuropeptides 1993;25(4):265-9.
1993: S F Moss; John Calam
Acid secretion and sensitivity to gastrin in patients with duodenal ulcer: effect of eradication of Helicobacter pylori.
Gut 1993;34(7):888-92.
1993: P J Hammond; A F Wade; M E Gwilliam; A Michael Peters; MJ Myers; S G Gilbey; Stephen R Bloom; John Calam
Amino acid infusion blocks renal tubular uptake of an indium-labelled somatostatin analogue.
British journal of cancer 1993;67(6):1437-9.
1993: Raymond J Playford; A C Woodman; P Clark; P Watanapa; D Vesey; P H Deprez; Robin C N Williamson; John Calam
Effect of luminal growth factor preservation on intestinal growth.
Lancet 1993;341(8849):843-8.
1993: P Watanapa; B Flaks; H Oztas; P H Deprez; John Calam; Robin C N Williamson
Inhibitory effect of a cholecystokinin antagonist on pancreatic carcinogenesis after pancreatobiliary diversion.
British journal of cancer 1993;67(4):663-7.
1992: S F Moss; Stephen Legon; Anne E Bishop; Julia M Polak; John Calam
Effect of Helicobacter pylori on gastric somatostatin in duodenal ulcer disease.
Lancet 1992;340(8825):930-2.
1992: Raymond J Playford; M A Benito-Orfila; Petros Nihoyannopoulos; K A Nandha; J Cockcroft; S Todd; Mohammad A Ghatei; J Domin; Stephen R Bloom; John Calam
Effects of peptide YY on the human cardiovascular system: reversal of responses to vasoactive intestinal peptide.
The American journal of physiology 1992;263(4 Pt 1):E740-7.
1992: P Watanapa; B Flaks; H Oztas; P H Deprez; John Calam; Robin C N Williamson
Duodenogastric reflux enhances growth and carcinogenesis in the rat pancreas.
The British journal of surgery 1992;79(8):791-4.
1992: K Beardshall; P Deprez; Raymond J Playford; M Alexander; John Calam
Effect of chymotrypsin on human cholecystokinin release: use of clostripain in the validation of a new radioimmunoassay.
Regulatory peptides 1992;40(1):1-12.
1992: P Watanapa; M Egan; P H Deprez; John Calam; Catherine Sarraf; Stuart McDonald; Robin C N Williamson
Role of cholecystokinin in pancreatic adaptation to massive enterectomy.
Gut 1992;33(7):959-64.
1992: S F Moss; P Ghosh; D M Thomas; James E Jackson; John Calam
Gastric antral vascular ectasia: maintenance treatment with oestrogen-progesterone.
Gut 1992;33(5):715-7.
1992: K Beardshall; S Moss; J Gill; S Levi; P Ghosh; Raymond J Playford; John Calam
Suppression of Helicobacter pylori reduces gastrin releasing peptide stimulated gastrin release in duodenal ulcer patients.
Gut 1992;33(5):601-3.
1992: S F Moss; D M Thomas; K Ayesu; S Levi; John Calam
Sucralfate diminishes basal acid output without affecting gastrin, H. pylori or gastritis in duodenal ulcer patients.
Alimentary pharmacology & therapeutics 1992;6(2):251-8.
1992: S Moss; John Calam
Helicobacter pylori and peptic ulcers: the present position.
Gut 1992;33(3):289-92.
1992: P Watanapa; B Flaks; H Oztas; P H Deprez; John Calam; Robin C N Williamson
Enhancing effect of partial gastrectomy on pancreatic carcinogenesis.
British journal of cancer 1992;65(3):383-7.
1992: S F Moss; Raymond J Playford; K Ayesu; S K Li; John Calam
pH-dependent secretion of gastrin in duodenal ulcer disease: effect of suppressing Helicobacter pylori.
Digestion 1992;52(3-4):173-8.
1991: Raymond J Playford; J J Batten; T C Freeman; K Beardshall; D A Vesey; G C Fenn; J H Baron; John Calam
Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol.
Gut 1991;32(11):1396-400.
1991: P Watanapa; E F Efa; K Beardshall; John Calam; Catherine Sarraf; Malcolm R Alison; Robin C N Williamson
Inhibitory effect of a cholecystokinin antagonist on the proliferative response of the pancreas to pancreatobiliary diversion.
Gut 1991;32(9):1049-54.
1991: P H Deprez; P Ghosh; Robert A Goodlad; S L Lacey; S Millership; Raymond J Playford; C Y Lee; John Calam
Hypergastrinaemia: a new mechanism.
Lancet 1991;338(8764):410-1.
1991: P Watanapa; K Bardshall; John Calam; Robin C N Williamson
Tropic role of enteroglucagon in pancreatic adaptation to subtotal enterectomy.
The British journal of surgery 1991;78(8):917-20.
1991: John Calam; Robert A Goodlad; C Y Lee; B Ratcliffe; M E Coates; G W Stamp; Nicholas A Wright
Achlorhydria-induced hypergastrinaemia: the role of bacteria.
Clinical science (London, England : 1979) 1991;80(4):281-4.
1991: Raymond J Playford; D A Vesey; S Haldane; M R Alison; John Calam
Dose-dependent effects of fentanyl on indomethacin-induced gastric damage.
Digestion 1991;49(4):198-203.
1990: T C Freeman; R Davies; John Calam
Interactions of pancreatic secretory trypsin inhibitor in small intestinal juice: its hydrolysis and protection by intraluminal factors.
Clinica chimica acta; international journal of clinical chemistry 1990;195(1-2):27-39.
1990: T C Freeman; Raymond J Playford; C Quinn; K Beardshall; L Poulter; J Young; John Calam
Pancreatic secretory trypsin inhibitor in gastrointestinal mucosa and gastric juice.
Gut 1990;31(11):1318-23.
1990: T C Freeman; B J Curry; John Calam; J R Woodburn
Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells.
Gastroenterology 1990;99(5):1414-20.
1990: Raymond J Playford; J Domin; J Beacham; K B Parmar; K Tatemoto; Stephen R Bloom; John Calam
Preliminary report: role of peptide YY in defence against diarrhoea.
Lancet 1990;335(8705):1555-7.
1990: Raymond J Playford; C H Matthews; M J Campbell; H T Delves; K K Hla; Humphrey Hodgson; John Calam
Bismuth induced encephalopathy caused by tri potassium dicitrato bismuthate in a patient with chronic renal failure.
Gut 1990;31(3):359-60.
1990: M Coupe; H Rees; C J Springer; Anne E Bishop; J A Morris; Julia M Polak; John Calam
Gastric enterochromaffin-like (ECL) cells in hypergastrinaemic duodenal ulcer disease.
Gut 1990;31(2):144-7.
1990: John Calam; Y Yiangou; G C Nikou; B J Chrysanthou; J L Beacham; Stephen R Bloom
Effects of preprovasoactive intestinal polypeptide-derived peptides on ileal output.
Gastroenterology 1990;98(2):505-8.
1989: S Levi; K Beardshall; I Swift; W Foulkes; Raymond J Playford; P Ghosh; John Calam
Antral Helicobacter pylori, hypergastrinaemia, and duodenal ulcers: effect of eradicating the organism.
BMJ (Clinical research ed.) 1989;299(6714):1504-5.
1989: K Beardshall; G Frost; Y Morarji; J Domin; Stephen R Bloom; John Calam
Saturation of fat and cholecystokinin release: implications for pancreatic carcinogenesis.
Lancet 1989;2(8670):1008-10.
1989: John Calam; Mohammad A Ghatei; J Domin; T E Adrian; M Myszor; S Gupta; C Tait; Stephen R Bloom
Regional differences in concentrations of regulatory peptides in human colon mucosal biopsy.
Digestive diseases and sciences 1989;34(8):1193-8.
1989: S Levi; K Beardshall; G Haddad; Raymond J Playford; P Ghosh; John Calam
Campylobacter pylori and duodenal ulcers: the gastrin link.
Lancet 1989;1(8648):1167-8.
1989: John Calam; C J Springer; J C Bojarski; M L Francis-Reme
Postprandial gastrin concentrations are higher in female patients with duodenal ulcers.
Digestion 1989;42(3):163-6.
1988: John Calam; Y Yiangou; B Chrysanthou; G Paul; A Mehta; Stephen R Bloom
Peptide histidine methionine (PHM) increases ileostomy output.
Regulatory peptides 1988;23(1):57-62.
1988: C J Springer; John Calam
Cholecystokinin cleavage to cholecystokinin-octapeptide in vivo and in vitro: accelerated cleavage in acute pancreatitis.
Gastroenterology 1988;95(1):143-50.
1988: John Calam; R J Unwin; S Dorudi; C Taylor; C J Springer; W S Peart
Effects of vasoactive intestinal polypeptide infusions on renal function in patients with liver disease.
Clinical and experimental pharmacology & physiology 1988;15(6):491-5.
1987: John Calam; J C Bojarski; C J Springer
Raw soya-bean flour increases cholecystokinin release in man.
The British journal of nutrition 1987;58(2):175-9.
1987: A P Savage; John Calam; C B Wood; Stephen R Bloom
SMS 201-995 treatment and advanced intestinal cancer: a pilot study.
Alimentary pharmacology & therapeutics 1987;1(2):133-9.
1987: L A Meldrum; J C Bojarski; John Calam
Effects of substance P and other neuropeptides on guinea-pig gall-bladder muscle.
Digestion 1987;37(4):193-9.
1986: L A Meldrum; J C Bojarski; John Calam
Effects of benzodiazepines on responses of guinea-pig ileum and gall-bladder and rat pancreatic acini to cholecystokinin.
European journal of pharmacology 1986;123(3):427-32.