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Nigel Calcutt
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29
Mizisin, Andrew
20
Tomlinson, David
8
Jolivalt, Corinne
7
Yaksh, Tony
7
Malmberg, Annika
7
Freshwater, Jason
7
Kalichman, Michael
6
Campana, Marie
6
O'Brien, John
4
Svensson, Camilla
4
Chaplan, Sandra
4
Fernyhough, Paul
3
Garcia, Michael
3
Luo, David
3
Gotow, Takahiro
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All Publications
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2009: Calcutt Nigel A; Lopez Veronica L; Bautista Arjel D; Mizisin Leah M; Torres Brenda R; Shroads Albert L; Mizisin Andrew P; Stacpoole Peter W
Peripheral neuropathy in rats exposed to dichloroacetate.
Journal of neuropathology and experimental neurology 2009;68(9):985-93.
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2009: Jolivalt Corinne G; Mizisin Leah M; Nelson Austin; Cunha Joice M; Ramos Khara M; Bonke Dieter; Calcutt Nigel A
B vitamins alleviate indices of neuropathic pain in diabetic rats.
European journal of pharmacology 2009;612(1-3):41-7.
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2009: Calcutt Nigel A; Cooper Mark E; Kern Tim S; Schmidt Ann Marie
Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials.
Nature reviews. Drug discovery 2009;8(5):417-29.
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2009: Garcia Michael L; Rao Mala V; Fujimoto Jiro; Garcia Virginia B; Shah Sameer B; Crum John; Gotow Takahiro; Uchiyama Yasuo; Ellisman Mark; Calcutt Nigel A; Cleveland Don W
Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(5):1277-84.
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2008: Jolivalt Corinne G; Lee Corinne A; Ramos Khara M; Calcutt Nigel A
Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters.
Pain 2008;140(1):48-57.
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2008: Beiswenger Kristina K; Calcutt Nigel A; Mizisin Andrew P
Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice.
Neuroscience letters 2008;442(3):267-72.
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2008: Jolivalt Corinne G; Vu Yvonne; Mizisin Leah M; Mizisin Andrew P; Calcutt Nigel A
Impaired prosaposin secretion during nerve regeneration in diabetic rats and protection of nerve regeneration by a prosaposin-derived peptide.
Journal of neuropathology and experimental neurology 2008;67(7):702-10.
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2008: Cunha Joice M; Jolivalt Corinne G; Ramos Khara M; Gregory Joshua A; Calcutt Nigel A; Mizisin Andrew P
Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors.
Metabolism: clinical and experimental 2008;57(7):873-81.
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2008: Calcutt Nigel A; Jolivalt Corinne G; Fernyhough Paul
Growth factors as therapeutics for diabetic neuropathy.
Current drug targets 2008;9(1):47-59.
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2008: Jolivalt Corinne G; Dacunha Joice M; Esch Fred S; Calcutt Nigel A
Central action of prosaptide TX14(A) against gp120-induced allodynia in rats.
European journal of pain (London, England) 2008;12(1):76-81.
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2008: Beiswenger Kristina K; Calcutt Nigel A; Mizisin Andrew P
Epidermal nerve fiber quantification in the assessment of diabetic neuropathy.
Acta histochemica 2008;110(5):351-62.
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2007: Calcutt Nigel A; Backonja Miroslav Misha
Pathogenesis of pain in peripheral diabetic neuropathy.
Current diabetes reports 2007;7(6):429-34.
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2007: Landgraf Rachelle R; Garrett Timothy J; Calcutt Nigel A; Stacpoole Peter W; Yost Richard A
MALDI-linear ion trap microprobe MS/MS studies of the effects of dichloroacetate on lipid content of nerve tissue.
Analytical chemistry 2007;79(21):8170-5.
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2007: Ramos Khara M; Jiang Yun; Svensson Camilla I; Calcutt Nigel A
Pathogenesis of spinally mediated hyperalgesia in diabetes.
Diabetes 2007;56(6):1569-76.
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2006: Jiang Yun; Calcutt Nigel A; Ramos Khara M; Mizisin Andrew P
Novel sites of aldose reductase immunolocalization in normal and streptozotocin-diabetic rats.
Journal of the peripheral nervous system : JPNS 2006;11(4):274-85.
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2006: Jolivalt C G; Jiang Y; Freshwater J D; Bartoszyk G D; Calcutt N A
Dynorphin A, kappa opioid receptors and the antinociceptive efficacy of asimadoline in streptozotocin-induced diabetic rats.
Diabetologia 2006;49(11):2775-85.
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2006: Malmberg Annika B; O'Connor William T; Glennon Jeffery C; Ceseña Rose; Calcutt Nigel A
Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats.
Brain research 2006;1115(1):48-53.
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2006: Calcutt Nigel A; Freshwater Jason D; Hauptmann Nils; Taylor Eve M; Mizisin Andrew P
Protection of sensory function in diabetic rats by Neotrofin.
European journal of pharmacology 2006;534(1-3):187-93.
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2006: Jolivalt Corinne G; Ramos Khara M; Herbetsson Katrin; Esch Fred S; Calcutt Nigel A
Therapeutic efficacy of prosaposin-derived peptide on different models of allodynia.
Pain 2006;121(1-2):14-21.
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2004: Malmberg Annika B; Mizisin Andrew P; Calcutt Nigel A; von Stein Thorsten; Robbins Wendye R; Bley Keith R
Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch.
Pain 2004;111(3):360-7.
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2004: Mizisin Andrew P; Vu Yvonne; Shuff Michelle; Calcutt Nigel A
Ciliary neurotrophic factor improves nerve conduction and ameliorates regeneration deficits in diabetic rats.
Diabetes 2004;53(7):1807-12.
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2004: Calcutt Nigel A
Experimental models of painful diabetic neuropathy.
Journal of the neurological sciences 2004;220(1-2):137-9.
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2004: Calcutt N A; Freshwater J D; Mizisin A P
Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor.
Diabetologia 2004;47(4):718-24.
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2004: Calcutt Nigel A
Modeling diabetic sensory neuropathy in rats.
Methods in molecular medicine 2004;99():55-65.
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2003: Garcia Michael L; Lobsiger Christian S; Shah Sameer B; Deerinck Tom J; Crum John; Young Darren; Ward Christopher M; Crawford Thomas O; Gotow Takahiro; Uchiyama Yasuo; Ellisman Mark H; Calcutt Nigel A; Cleveland Don W
NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth.
The Journal of cell biology 2003;163(5):1011-20.
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2003: Svensson Camilla I; Marsala Martin; Westerlund Anna; Calcutt Nigel A; Campana Wendy M; Freshwater Jason D; Catalano Rosanne; Feng Ying; Protter Andrew A; Scott Brian; Yaksh Tony L
Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing.
Journal of neurochemistry 2003;86(6):1534-44.
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2003: Sayers Nicola M; Beswick Lisa J; Middlemas Alicia; Calcutt Nigel A; Mizisin Andrew P; Tomlinson David R; Fernyhough Paul
Neurotrophin-3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of streptozocin-induced diabetic rats.
Diabetes 2003;52(9):2372-80.
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2003: Huang Tze-Jen; Price Sally A; Chilton Lucy; Calcutt Nigel A; Tomlinson David R; Verkhratsky Alex; Fernyhough Paul
Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.
Diabetes 2003;52(8):2129-36.
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2003: Calcutt Nigel A; Allendoerfer Karen L; Mizisin Andrew P; Middlemas Alicia; Freshwater Jason D; Burgers Monica; Ranciato Rigel; Delcroix Jean-Dominique; Taylor Frederick R; Shapiro Renee; Strauch Kathy; Dudek Henryk; Engber Thomas M; Galdes Alphonse; Rubin Lee L; Tomlinson David R
Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy.
The Journal of clinical investigation 2003;111(4):507-14.
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2002: Calcutt Nigel A
Future treatments for diabetic neuropathy: clues from experimental neuropathy.
Current diabetes reports 2002;2(6):482-8.
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2002: Luo Z D; Calcutt N A; Higuera E S; Valder C R; Song Y-H; Svensson C I; Myers R R
Injury type-specific calcium channel alpha 2 delta-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin.
The Journal of pharmacology and experimental therapeutics 2002;303(3):1199-205.
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2002: Rao Mala V; Garcia Michael L; Miyazaki Yukio; Gotow Takahiro; Yuan Aidong; Mattina Salvatore; Ward Chris M; Calcutt Nigel A; Uchiyama Yasuo; Nixon Ralph A; Cleveland Don W
Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.
The Journal of cell biology 2002;158(4):681-93.
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2002: Freshwater Jason D; Svensson Camilla I; Malmberg Annika B; Calcutt Nigel A
Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats.
Diabetes 2002;51(7):2249-55.
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2002: Calcutt Nigel A
Potential mechanisms of neuropathic pain in diabetes.
International review of neurobiology 2002;50():205-28.
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2001: Mizisin A P; Steinhardt R C; O'Brien J S; Calcutt N A
TX14(A), a prosaposin-derived peptide, reverses established nerve disorders in streptozotocin-diabetic rats and prevents them in galactose-fed rats.
Journal of neuropathology and experimental neurology 2001;60(10):953-60.
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2001: Rende M; Brizi E; Donato R; Provenzano C; Bruno R; Mizisin A P; Garrett R S; Calcutt N A; Campana W M; O'Brien J S
Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury.
Muscle & nerve 2001;24(6):799-808.
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2000: Calcutt N A; Freshwater J D; O'Brien J S
Protection of sensory function and antihyperalgesic properties of a prosaposin-derived peptide in diabetic rats.
Anesthesiology 2000;93(5):1271-8.
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2000: Campana W M; Mohiuddin L; Misasi R; O'Brien J S; Calcutt N A
Prosaposin-derived peptides enhanced sprouting of sensory neurons in vitro and induced sprouting at motor endplates in vivo.
Journal of the peripheral nervous system : JPNS 2000;5(3):126-30.
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2000: Calcutt N A; Stiller C; Gustafsson H; Malmberg A B
Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats.
Brain research 2000;856(1-2):20-7.
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1999: Luo Z D; Chaplan S R; Scott B P; Cizkova D; Calcutt N A; Yaksh T L
Neuronal nitric oxide synthase mRNA upregulation in rat sensory neurons after spinal nerve ligation: lack of a role in allodynia development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(21):9201-8.
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1999: Calcutt N A; Campana W M; Eskeland N L; Mohiuddin L; Dines K C; Mizisin A P; O'Brien J S
Prosaposin gene expression and the efficacy of a prosaposin-derived peptide in preventing structural and functional disorders of peripheral nerve in diabetic rats.
Journal of neuropathology and experimental neurology 1999;58(6):628-36.
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1999: Ceseña R M; Calcutt N A
Gabapentin prevents hyperalgesia during the formalin test in diabetic rats.
Neuroscience letters 1999;262(2):101-4.
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1999: Dines K C; Calcutt N A; Nunag K D; Mizisin A P; Kalichman M W
Effects of hindlimb temperature on sciatic nerve laser Doppler vascular conductance in control and streptozotocin-diabetic rats.
Journal of the neurological sciences 1999;163(1):17-24.
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1999: Shelton G D; Calcutt N A; Garrett R S; Gu D; Sarvetnick N; Campana W M; Powell H C
Necrotizing myopathy induced by overexpression of interferon-gamma in transgenic mice.
Muscle & nerve 1999;22(2):156-65.
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1999: Mizisin A P; Calcutt N A; Tomlinson D R; Gallagher A; Fernyhough P
Neurotrophin-3 reverses nerve conduction velocity deficits in streptozotocin-diabetic rats.
Journal of the peripheral nervous system : JPNS 1999;4(3-4):211-21.
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1998: Calcutt N A; Chen P; Hua X Y
Effects of diabetes on tissue content and evoked release of calcitonin gene-related peptide-like immunoreactivity from rat sensory nerves.
Neuroscience letters 1998;254(3):129-32.
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1998: Calcutt N A; Dines K C; Ceseña R M
Effects of the peptide HP228 on nerve disorders in diabetic rats.
Metabolism: clinical and experimental 1998;47(6):650-6.
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1998: Campana W M; Eskeland N; Calcutt N A; Misasi R; Myers R R; O'Brien J S
Prosaptide prevents paclitaxel neurotoxicity.
Neurotoxicology 1998;19(2):237-44.
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1997: Calcutt N A; Chaplan S R
Spinal pharmacology of tactile allodynia in diabetic rats.
British journal of pharmacology 1997;122(7):1478-82.
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1997: Mizisin A P; Bache M; DiStefano P S; Acheson A; Lindsay R M; Calcutt N A
BDNF attenuates functional and structural disorders in nerves of galactose-fed rats.
Journal of neuropathology and experimental neurology 1997;56(12):1290-301.
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1997: Hua X Y; Calcutt N A; Malmberg A B
Neonatal capsaicin treatment abolishes formalin-induced spinal PGE2 release.
Neuroreport 1997;8(9-10):2325-9.
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1997: Mizisin A P; Li L; Calcutt N A
Sorbitol accumulation and transmembrane efflux in osmotically stressed JS1 schwannoma cells.
Neuroscience letters 1997;229(1):53-6.
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1997: Mizisin A P; Calcutt N A; DiStefano P S; Acheson A; Longo F M
Aldose reductase inhibition increases CNTF-like bioactivity and protein in sciatic nerves from galactose-fed and normal rats.
Diabetes 1997;46(4):647-52.
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1997: Malmberg A B; Hedner T; Fallgren B; Calcutt N A
The effect of alpha-trinositol (D-myo-inositol 1,2,6-trisphosphate) on formalin-evoked spinal amino acid and prostaglandin E2 levels.
Brain research 1997;747(1):160-4.
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1997: Okuse K; Chaplan S R; McMahon S B; Luo Z D; Calcutt N A; Scott B P; Akopian A N; Wood J N
Regulation of expression of the sensory neuron-specific sodium channel SNS in inflammatory and neuropathic pain.
Molecular and cellular neurosciences 1997;10(3-4):196-207.
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1996: Calcutt N A; Jorge M C; Yaksh T L; Chaplan S R
Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine.
Pain 1996;68(2-3):293-9.
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1996: Brett F M; Kalichman M W; Calcutt N A; Mizisin A P
Effects of seven days of galactose feeding and aldose reductase inhibition on mast cells and vessel morphometry in rat sciatic nerve.
Journal of the neurological sciences 1996;141(1-2):6-12.
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1996: Belai A; Calcutt N A; Carrington A L; Diemel L T; Tomlinson D R; Burnstock G
Enteric neuropeptides in streptozotocin-diabetic rats; effects of insulin and aldose reductase inhibition.
Journal of the autonomic nervous system 1996;58(3):163-9.
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1996: Mizisin A P; Li L; Perello M; Freshwater J D; Kalichman M W; Roux L; Calcutt N A
Polyol pathway and osmoregulation in JS1 Schwann cells grown in hyperglycemic and hyperosmotic conditions.
The American journal of physiology 1996;270(1 Pt 2):F90-7.
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1995: Calcutt N A; Li L; Yaksh T L; Malmberg A B
Different effects of two aldose reductase inhibitors on nociception and prostaglandin E.
European journal of pharmacology 1995;285(2):189-97.
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1995: Kalichman M W; Powell H C; Calcutt N A; Mizisin A P
Mast cell degranulation and blood-nerve barrier permeability in rat sciatic nerve after 7 days of hyperglycemia.
The American journal of physiology 1995;268(2 Pt 2):H740-8.
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1995: Gu D; Wogensen L; Calcutt N A; Xia C; Zhu S; Merlie J P; Fox H S; Lindstrom J; Powell H C; Sarvetnick N
Myasthenia gravis-like syndrome induced by expression of interferon gamma in the neuromuscular junction.
The Journal of experimental medicine 1995;181(2):547-57.
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1994: Calcutt N A; Malmberg A B; Yamamoto T; Yaksh T L
Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats.
Pain 1994;58(3):413-20.
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1994: Calcutt N A; McMurray H F; Moorhouse D F; Bache M; Parthasarathy S; Powell H C; Mizisin A P
Inhibition of macrophage chemotaxis and peripheral nerve regeneration in normal and hyperglycemic rats by the aldose reductase inhibitor Tolrestat.
Experimental neurology 1994;128(2):226-32.
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1994: Calcutt N A; Mizisin A P; Kalichman M W
Aldose reductase inhibition, Doppler flux and conduction in diabetic rat nerve.
European journal of pharmacology 1994;251(1):27-33.
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1993: Calcutt N A; Mizisin A P; Yaksh T L
Impaired induction of vasoactive intestinal polypeptide after sciatic nerve injury in the streptozotocin-diabetic rat.
Journal of the neurological sciences 1993;119(2):154-61.
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1993: Malmberg A B; Yaksh T L; Calcutt N A
Anti-nociceptive effects of the GM1 ganglioside derivative AGF 44 on the formalin test in normal and streptozotocin-diabetic rats.
Neuroscience letters 1993;161(1):45-8.
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1993: Carrington A L; Calcutt N A; Ettlinger C B; Gustafsson T; Tomlinson D R
Effects of treatment with myo-inositol or its 1,2,6-trisphosphate (PP56) on nerve conduction in streptozotocin-diabetes.
European journal of pharmacology 1993;237(2-3):257-63.
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1993: Mizisin A P; Kalichman M W; Calcutt N A; Myers R R; Powell H C
Decreased endoneurial fluid electrolytes in normal rat sciatic nerve after aldose reductase inhibition.
Journal of the neurological sciences 1993;116(1):67-72.
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1992: Kalichman M W; Calcutt N A
Local anesthetic-induced conduction block and nerve fiber injury in streptozotocin-diabetic rats.
Anesthesiology 1992;77(5):941-7.
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1992: Calcutt N A; Carrington A L; Ettlinger C B; Tomlinson D R
The effect of mixed bovine brain gangliosides on hypoxic conduction block in control and streptozotocin-diabetic rats.
Journal of the neurological sciences 1992;109(1):96-101.
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1992: Calcutt N A; Muir D; Powell H C; Mizisin A P
Reduced ciliary neuronotrophic factor-like activity in nerves from diabetic or galactose-fed rats.
Brain research 1992;575(2):320-4.
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1991: Mizisin A P; Calcutt N A
Dose-dependent alterations in nerve polyols and (Na+,K+)-ATPase activity in galactose intoxication.
Metabolism: clinical and experimental 1991;40(11):1207-12.
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1991: Willars G B; Calcutt N A; Tomlinson D R
Nerve conduction velocity and axonal transport of 6-phosphofructokinase activity in galactose-fed rats.
Journal of the neurological sciences 1991;104(1):46-51.
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1991: Carrington A L; Ettlinger C B; Calcutt N A; Tomlinson D R
Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats.
Diabetologia 1991;34(6):397-401.
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1991: Calcutt N A; Ettlinger C B; Carrington A L; Diemel L; Tomlinson D R
Resistance to hypoxic conduction block in sciatic nerves of rats with streptozotocin-induced diabetes mellitus.
Journal of the neurological sciences 1991;103(1):116-23.
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1990: Calcutt N A; Tomlinson D R; Biswas S
Coexistence of nerve conduction deficit with increased Na(+)-K(+)-ATPase activity in galactose-fed mice. Implications for polyol pathway and diabetic neuropathy.
Diabetes 1990;39(6):663-6.
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1990: Calcutt N A; Tomlinson D R; Willars G B; Keen P
Axonal transport of substance P-like immunoreactivity in ganglioside-treated diabetic rats.
Journal of the neurological sciences 1990;96(2-3):283-91.
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1989: Willars G B; Calcutt N A; Compton A M; Tomlinson D R; Keen P
Substance P levels in peripheral nerve, skin, atrial myocardium and gastrointestinal tract of rats with long-term diabetes mellitus. Effects of aldose reductase inhibition.
Journal of the neurological sciences 1989;91(1-2):153-64.
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1989: Tomlinson D R; Willars G B; Calcutt N A; Compton A M; Macdonald I A; Clarke H E; Keen P
Effects of sorbinil treatment in rats with chronic streptozotocin-diabetes; changes in lens and in substance P and catecholamines in the iris.
Current eye research 1989;8(4):357-63.
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1988: Calcutt N A; Willars G B; Tomlinson D R
Axonal transport of choline acetyltransferase and 6-phosphofructokinase activities in genetically diabetic mice.
Muscle & nerve 1988;11(12):1206-10.
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1988: Lambourne J E; Brown A M; Calcutt N; Tomlinson D R; Willars G B
Adenosine triphosphatase in nerves and ganglia of rats with streptozotocin-induced diabetes or galactosaemia; effects of aldose reductase inhibition.
Diabetologia 1988;31(6):379-84.
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1988: Calcutt N A; Willars G B; Tomlinson D R
Statil-sensitive polyol formation in nerve of galactose-fed mice.
Metabolism: clinical and experimental 1988;37(5):450-3.
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1988: Calcutt N A; Tomlinson D R; Willars G B
Ganglioside treatment of streptozotocin-diabetic rats prevents defective axonal transport of 6-phosphofructokinase activity.
Journal of neurochemistry 1988;50(5):1478-83.
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1988: Calcutt N A; Tomlinson D R; Willars G B
Ganglioside treatment of diabetic rats; effects on nerve adenosine triphosphatase activity and motor nerve conduction velocity.
Life sciences 1988;42(16):1515-20.
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1987: Willars G B; Calcutt N A; Tomlinson D R
Reduced anterograde and retrograde accumulation of axonally transported phosphofructokinase in streptozotocin-diabetic rats: effects of insulin and the aldose reductase inhibitor 'Statil'.
Diabetologia 1987;30(4):239-43.
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