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Marie-Caroline Le Bousse-Kerdilès

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Christophe Desterke; Chrystele Bilhou-Nabéra; Bernadette Guerton; Christophe Martinaud; Carole Tonetti; Denis Clay; Paola Guglielmelli; Alessandro Vannucchi; Dominique Bordessoule; Hans Hasselbalch; Brigitte Dupriez; Nassima Benzoubir; Marie-Françoise Bourgeade; Olivier Pierre-Louis; Vladimir Lazar; William Vainchenker; Annelise Bennaceur-Griscelli; Heinz Gisslinger; Stéphane Giraudier; Marie-Caroline Le Bousse-Kerdilès
FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.
Fanny Baran-Marszak; Hajer Magdoud; Christophe Desterke; Anabell Alvarado; Claudine Roger; Stéphanie Harel; Elizabeth Mazoyer; Bruno Cassinat; Sylvie Chevret; Carole Tonetti; Stéphane Giraudier; Pierre Fenaux; Florence Cymbalista; Nadine Varin-Blank; Marie-Caroline Le Bousse-Kerdilès; Jean-Jacques Kiladjian; Laura Velazquez
Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms.
Jean-Jacques Lataillade; Philippe Brunet de la Grange; Georges Uzan; Marie-Caroline Le Bousse-Kerdilès
[Are stem cells as old as their niches? The quest for eternal life...].

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All Publications

2011: Christophe Desterke; Chrystele Bilhou-Nabéra; Bernadette Guerton; Christophe Martinaud; Carole Tonetti; Denis Clay; Paola Guglielmelli; Alessandro Vannucchi; Dominique Bordessoule; Hans Hasselbalch; Brigitte Dupriez; Nassima Benzoubir; Marie-Françoise Bourgeade; Olivier Pierre-Louis; Vladimir Lazar; William Vainchenker; Annelise Bennaceur-Griscelli; Heinz Gisslinger; Stéphane Giraudier; Marie-Caroline Le Bousse-Kerdilès
FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.
Cancer research 2011;71(8):2901-15.
2010: Fanny Baran-Marszak; Hajer Magdoud; Christophe Desterke; Anabell Alvarado; Claudine Roger; Stéphanie Harel; Elizabeth Mazoyer; Bruno Cassinat; Sylvie Chevret; Carole Tonetti; Stéphane Giraudier; Pierre Fenaux; Florence Cymbalista; Nadine Varin-Blank; Marie-Caroline Le Bousse-Kerdilès; Jean-Jacques Kiladjian; Laura Velazquez
Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms.
Blood 2010;116(26):5961-71.
2010: Jean-Jacques Lataillade; Philippe Brunet de la Grange; Georges Uzan; Marie-Caroline Le Bousse-Kerdilès
[Are stem cells as old as their niches? The quest for eternal life...].
Médecine sciences : M/S 2010;26(6-7):582-5.
2009: Olivier Pierre-Louis; Denis Clay; Philippe Brunet de la Grange; Istvan Blazsek; Christophe Desterke; Bernadette Guerton; Camille Blondeau; Jean-Valère Malfuson; Marie Prat; Annelise Bennaceur-Griscelli; Jean-Jacques Lataillade; Marie-Caroline Le Bousse-Kerdilès
Dual SP/ALDH functionalities refine the human hematopoietic Lin-CD34+CD38- stem/progenitor cell compartment.
Stem cells (Dayton, Ohio) 2009;27(10):2552-62.
2009: julien villeneuve; Anna Block; Marie-Caroline Le Bousse-Kerdilès; Sébastien Lepreux; Paquita Nurden; Jean Ripoche; Alan T Nurden
Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: a novel organization for these secreted proteins.
Experimental hematology 2009;37(7):849-56.
2008: Aurélie Chabanon; desterke christophe; Emilie Rodenburger; Denis Clay; Bernadette Guerton; Laetitia Boutin; Annelise Bennaceur-Griscelli; Olivier Pierre-Louis; Georges Uzan; Lucile Abecassis; Marie-Françoise Bourgeade; Jean-Jacques Lataillade; Marie-Caroline Le Bousse-Kerdilès
A cross-talk between stromal cell-derived factor-1 and transforming growth factor-beta controls the quiescence/cycling switch of CD34(+) progenitors through FoxO3 and mammalian target of rapamycin.
Stem cells (Dayton, Ohio) 2008;26(12):3150-61.
2008: Jean-Jacques Lataillade; Olivier Pierre-Louis; Hans Carl Hasselbalch; Georges Uzan; Claude Jasmin; Marie-Claire Martyré; Marie-Caroline Le Bousse-Kerdilès
Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence.
Blood 2008;112(8):3026-35.
2008: R Chaligné; C Tonetti; R Besancenot; L Roy; C Marty; P Mossuz; J-J Kiladjian; G Socié; D Bordessoule; Marie-Caroline Le Bousse-Kerdilès; W Vainchenker; S Giraudier
New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition.
Leukemia 2008;22(8):1557-66.
2008: Costanza Bogani; Vanessa Ponziani; Paola Guglielmelli; desterke christophe; Vittorio Rosti; Alberto Bosi; Marie-Caroline Le Bousse-Kerdilès; Giovanni Barosi; Alessandro M Vannucchi
Hypermethylation of CXCR4 promoter in CD34+ cells from patients with primary myelofibrosis.
Stem cells (Dayton, Ohio) 2008;26(8):1920-30.
2008: Marie-Caroline Le Bousse-Kerdilès; Marie-Claire Martyré; Michel Samson
Cellular and molecular mechanisms underlying bone marrow and liver fibrosis: a review.
European cytokine network 2008;19(2):69-80.
2007: Paola Guglielmelli; Roberta Zini; Costanza Bogani; Simona Salati; Alessandro Pancrazzi; Elisa Bianchi; Francesco Mannelli; Sergio Ferrari; Marie-Caroline Le Bousse-Kerdilès; Alberto Bosi; Giovanni Barosi; Anna Rita Migliaccio; Rossella Manfredini; Alessandro M Vannucchi
Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1).
Stem cells (Dayton, Ohio) 2007;25(1):165-73.
2006: Peter J Campbell; E Joanna Baxter; Philip A Beer; Linda Maree SCOTT; Anthony J Bench; Brian J P Huntly; Wendy N Erber; Rajko Kusec; Thomas Stauffer Larsen; Stéphane Giraudier; Marie-Caroline Le Bousse-Kerdilès; Martin Griesshammer; John T Reilly; Betty Y Cheung; Claire N Harrison; Anthony R Green
Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation.
Blood 2006;108(10):3548-55.
2006: Peter J Campbell; Martin Griesshammer; Konstanze Döhner; Hartmut Döhner; Rajko Kusec; Hans Carl Hasselbalch; Thomas Stauffer Larsen; Niels Pallisgaard; Stéphane Giraudier; Marie-Caroline Le Bousse-Kerdilès; desterke christophe; Bernadette Guerton; Brigitte Dupriez; Dominique Bordessoule; Pierre Fenaux; Jean-Jacques Kiladjian; Jean-François Viallard; Josette Brière; Claire N Harrison; Anthony R Green; John T Reilly
V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis.
Blood 2006;107(5):2098-100.
2005: Marie-Claire Martyré; Marie-Caroline Le Bousse-Kerdilès
Stem cell dysregulation in myelofibrosis with myeloid metaplasia: current data on growth factor and transcription factor involvement.
Seminars in oncology 2005;32(4):373-9.
2005: Jean-Jacques Lataillade; Denis Clay; Catherine David; Laetitia Boutin; Bernadette Guerton; Michel Drouet; Francis Hérodin; Marie-Caroline Le Bousse-Kerdilès
Phenotypic and functional characteristics of CD34+ cells are related to their anatomical environment: is their versatility a prerequisite for their bio-availability?
Journal of leukocyte biology 2005;77(5):634-43.
2005: Sharareh Emadi; Denis Clay; desterke christophe; Bernadette Guerton; Eliane Maquarre; Agnès Charpentier; Claude Jasmin; Marie-Caroline Le Bousse-Kerdilès
IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis.
Blood 2005;105(2):464-73.
2004: Jean-Jacques Lataillade; Jorge Domenech; Marie-Caroline Le Bousse-Kerdilès
Stromal cell-derived factor-1 (SDF-1)\CXCR4 couple plays multiple roles on haematopoietic progenitors at the border between the old cytokine and new chemokine worlds: survival, cell cycling and trafficking.
European cytokine network 2004;15(3):177-88.
2003: Virginie Steunou; Marie-Caroline Le Bousse-Kerdilès; A Colin-Micouin; Denis Clay; Sylvie Chevillard; Marie-Claire Martyré
Altered transcription of the stem cell leukemia gene in myelofibrosis with myeloid metaplasia.
Leukemia 2003;17(10):1998-2006.
2003: Chrystèle Bilhou-Nabéra; Christophe Brigaudeau; Denis Clay; Joris Andrieux; Jean-Luc Lai; Danièle Brouty-Boyé; Christine Vignon; Marie-Josée Gharbi; Marie-Caroline Le Bousse-Kerdilès; Vincent Praloran
Does cytogenetic mosaicism in CD34+CD38low cells reflect the persistence of normal primitive hematopoietic progenitors in myeloid metaplasia with myelofibrosis?
Blood 2003;102(4):1551-2.
2002: Jean-Jacques Lataillade; Denis Clay; philippe Bourin; Francis Hérodin; Catherine Dupuy; Claude Jasmin; Marie-Caroline Le Bousse-Kerdilès
Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism.
Blood 2002;99(4):1117-29.
2001: Danièle Brouty-Boyé; Diane Briard; Bruno Azzarone; Marie-Caroline Le Bousse-Kerdilès; Denis Clay; C Pottin-Clémenceau; Claude Jasmin
Effects of human fibroblasts from myelometaplasic and non-myelometaplasic hematopoietic tissues on CD34+ stem cells.
International journal of cancer. Journal international du cancer 2001;92(4):484-8.
2001: Denis Clay; Eric Rubinstein; Zohar Mishal; A Anjo; Michel Prenant; Claude Jasmin; Claude Boucheix; Marie-Caroline Le Bousse-Kerdilès
CD9 and megakaryocyte differentiation.
Blood 2001;97(7):1982-9.
2001: Marie-Caroline Le Bousse-Kerdilès; Marie-Claire Martyré
Involvement of the fibrogenic cytokines, TGF-beta and bFGF, in the pathogenesis of idiopathic myelofibrosis.
Pathologie-biologie 2001;49(2):153-7.
2000: Jean-Jacques Lataillade; Denis Clay; Catherine Dupuy; S Rigal; Claude Jasmin; philippe Bourin; Marie-Caroline Le Bousse-Kerdilès
Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival.
Blood 2000;95(3):756-68.
1999: S Oshevski; Marie-Caroline Le Bousse-Kerdilès; Denis Clay; Z Levashova; N Debili; N Vitral; Claude Jasmin; M Castagna
Differential expression of protein kinase C isoform transcripts in human hematopoietic progenitors undergoing differentiation.
Biochemical and biophysical research communications 1999;263(3):603-9.
1999: Marie-Caroline Le Bousse-Kerdilès; Marie-Claire Martyré
Dual implication of fibrogenic cytokines in the pathogenesis of fibrosis and myeloproliferation in myeloid metaplasia with myelofibrosis.
Annals of hematology 1999;78(10):437-44.
1999: Marie-Caroline Le Bousse-Kerdilès; Marie-Claire Martyré
Myelofibrosis: pathogenesis of myelofibrosis with myeloid metaplasia. French INSERM Research Network on Myelofibrosis with Myeloid Metaplasia.
Springer seminars in immunopathology 1999;21(4):491-508.
1996: Marie-Caroline Le Bousse-Kerdilès; Sylvie Chevillard; A Charpentier; N Romquin; Denis Clay; Florence Smadja-Joffe; V Praloran; Brigitte Dupriez; Jean-Loup Demory; Claude Jasmin; Marie-Claire Martyré
Differential expression of transforming growth factor-beta, basic fibroblast growth factor, and their receptors in CD34+ hematopoietic progenitor cells from patients with myelofibrosis and myeloid metaplasia.
Blood 1996;88(12):4534-46.
1992: Marie-Caroline Le Bousse-Kerdilès; M Souyri; Florence Smadja-Joffe; V Praloran; Claude Jasmin; H J Ziltener
Enhanced hematopoietic growth factor production in an experimental myeloproliferative syndrome.
Blood 1992;79(12):3179-87.