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Alan Lehmann
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22
Broughton, Bernard
19
Arlett, Colin
17
Carr, Antony
15
Stefanini, Miria
14
Kannouche, Patricia
12
Nardo, Tiziana
10
Sarasin, Alain
10
Botta, Elena
9
Watts, Felicity
8
Jaspers, Nicolaas
8
Green, Catherine
8
Green, Michael
6
Jeggo, Penny
6
Hoeijmakers, Jan
6
Berneburg, Mark
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All Publications
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2009: Brown Stephanie; Niimi Atsuko; Lehmann Alan R
Ubiquitination and deubiquitination of PCNA in response to stalling of the replication fork.
Cell cycle (Georgetown, Tex.) 2009;8(5):689-92.
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2009: Sabbioneda Simone; Green Catherine M; Bienko Marzena; Kannouche Patricia; Dikic Ivan; Lehmann Alan R
Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):E20; author reply E21.
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2008: Sabbioneda Simone; Gourdin Audrey M; Green Catherine M; Zotter Angelika; Giglia-Mari Giuseppina; Houtsmuller Adriaan; Vermeulen Wim; Lehmann Alan R
Effect of proliferating cell nuclear antigen ubiquitination and chromatin structure on the dynamic properties of the Y-family DNA polymerases.
Molecular biology of the cell 2008;19(12):5193-202.
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2008: Lehmann Alan R
XPD structure reveals its secrets.
DNA repair 2008;7(11):1912-5.
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2008: Niimi Atsuko; Brown Stephanie; Sabbioneda Simone; Kannouche Patricia L; Scott Andrew; Yasui Akira; Green Catherine M; Lehmann Alan R
Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16125-30.
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2008: Anttinen Anu; Koulu Leena; Nikoskelainen Eeva; Portin Raija; Kurki Timo; Erkinjuntti Matti; Jaspers Nicolaas G J; Raams Anja; Green Michael H L; Lehmann Alan R; Wing Jonathan F; Arlett Colin F; Marttila Reijo J
Neurological symptoms and natural course of xeroderma pigmentosum.
Brain : a journal of neurology 2008;131(Pt 8):1979-89.
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2008: Kleijer Wim J; Laugel Vincent; Berneburg Mark; Nardo Tiziana; Fawcett Heather; Gratchev Alexei; Jaspers Nicolaas G J; Sarasin Alain; Stefanini Miria; Lehmann Alan R
Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy.
DNA repair 2008;7(5):744-50.
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2008: Taylor Elaine M; Copsey Alice C; Hudson Jessica J R; Vidot Susanne; Lehmann Alan R
Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex.
Molecular and cellular biology 2008;28(4):1197-206.
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2008: Arlett C F; Green M H L; Rogers P B; Lehmann A R; Plowman P N
Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts.
The British journal of radiology 2008;81(961):51-8.
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2007: Lehmann Alan R; Niimi Atsuko; Ogi Tomoo; Brown Stephanie; Sabbioneda Simone; Wing Jonathan F; Kannouche Patricia L; Green Catherine M
Translesion synthesis: Y-family polymerases and the polymerase switch.
DNA repair 2007;6(7):891-9.
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2007: Botta Elena; Offman Judith; Nardo Tiziana; Ricotti Roberta; Zambruno Giovanna; Sansone Daniela; Balestri Paolo; Raams Anja; Kleijer Wim J; Jaspers Nicolaas G J; Sarasin Alain; Lehmann Alan R; Stefanini Miria
Mutations in the C7orf11 (TTDN1) gene in six nonphotosensitive trichothiodystrophy patients: no obvious genotype-phenotype relationships.
Human mutation 2007;28(1):92-6.
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2006: Palecek Jan; Vidot Susanne; Feng Min; Doherty Aidan J; Lehmann Alan R
The Smc5-Smc6 DNA repair complex. bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits.
The Journal of biological chemistry 2006;281(48):36952-9.
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2006: Lehmann Alan R; Fuchs Robert P
Gaps and forks in DNA replication: Rediscovering old models.
DNA repair 2006;5(12):1495-8.
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2006: Lehmann Alan R
New functions for Y family polymerases.
Molecular cell 2006;24(4):493-5.
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2006: Friedberg Errol C; Aguilera Andres; Gellert Martin; Hanawalt Philip C; Hays John B; Lehmann Alan R; Lindahl Tomas; Lowndes Noel; Sarasin Alain; Wood Richard D
DNA repair: from molecular mechanism to human disease.
DNA repair 2006;5(8):986-96.
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2006: Andressoo Jaan-Olle; Mitchell James R; de Wit Jan; Hoogstraten Deborah; Volker Marcel; Toussaint Wendy; Speksnijder Ewoud; Beems Rudolph B; van Steeg Harry; Jans Judith; de Zeeuw Chris I; Jaspers Nicolaas G J; Raams Anja; Lehmann Alan R; Vermeulen Wim; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria.
Cancer cell 2006;10(2):121-32.
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2006: Lehmann Alan R
Translesion synthesis in mammalian cells.
Experimental cell research 2006;312(14):2673-6.
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2006: Sidwell R U; Sandison A; Wing J; Fawcett H D; Seet J-E; Fisher C; Nardo T; Stefanini M; Lehmann A R; Cream J J
A novel mutation in the XPA gene associated with unusually mild clinical features in a patient who developed a spindle cell melanoma.
The British journal of dermatology 2006;155(1):81-8.
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2006: Frampton Jonathan; Irmisch Anja; Green Catherine M; Neiss Andrea; Trickey Michelle; Ulrich Helle D; Furuya Kanji; Watts Felicity Z; Carr Antony M; Lehmann Alan R
Postreplication repair and PCNA modification in Schizosaccharomyces pombe.
Molecular biology of the cell 2006;17(7):2976-85.
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2006: Ogi Tomoo; Lehmann Alan R
The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair.
Nature cell biology 2006;8(6):640-2.
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2006: Arlett C F; Plowman P N; Rogers P B; Parris C N; Abbaszadeh F; Green M H L; McMillan T J; Bush C; Foray N; Lehmann A R
Clinical and cellular ionizing radiation sensitivity in a patient with xeroderma pigmentosum.
The British journal of radiology 2006;79(942):510-7.
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2006: Lehmann Alan R
Clubbing together on clamps: The key to translesion synthesis.
DNA repair 2006;5(3):404-7.
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2005: Bienko Marzena; Green Catherine M; Crosetto Nicola; Rudolf Fabian; Zapart Grzegorz; Coull Barry; Kannouche Patricia; Wider Gerhard; Peter Matthias; Lehmann Alan R; Hofmann Kay; Dikic Ivan
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.
Science (New York, N.Y.) 2005;310(5755):1821-4.
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2005: Albertella Mark R; Green Catherine M; Lehmann Alan R; O'Connor Mark J
A role for polymerase eta in the cellular tolerance to cisplatin-induced damage.
Cancer research 2005;65(21):9799-806.
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2005: Theron Therina; Fousteri Maria I; Volker Marcel; Harries Lorna W; Botta Elena; Stefanini Miria; Fujimoto Mitsuo; Andressoo Jaan-Olle; Mitchell Jay; Jaspers Nicolaas G J; McDaniel Lisa D; Mullenders Leon H; Lehmann Alan R
Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome.
Molecular and cellular biology 2005;25(18):8368-78.
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2005: Fujimoto Mitsuo; Leech Suzanne N; Theron Therina; Mori Masato; Fawcett Heather; Botta Elena; Nozaki Yasuyuki; Yamagata Takanori; Moriwaki Shin-Ichi; Stefanini Miria; Momoi Mariko Y; Nakagawa Hidemi; Shuster Sam; Moss Celia; Lehmann Alan R
Two new XPD patients compound heterozygous for the same mutation demonstrate diverse clinical features.
The Journal of investigative dermatology 2005;125(1):86-92.
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2005: Friedberg Errol C; Lehmann Alan R; Fuchs Robert P P
Trading places: how do DNA polymerases switch during translesion DNA synthesis?
Molecular cell 2005;18(5):499-505.
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2005: Lehmann Alan R
The role of SMC proteins in the responses to DNA damage.
DNA repair 2005;4(3):309-14.
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2005: Lehmann Alan R
Replication of damaged DNA by translesion synthesis in human cells.
FEBS letters 2005;579(4):873-6.
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2005: Andrews Emily A; Palecek Jan; Sergeant John; Taylor Elaine; Lehmann Alan R; Watts Felicity Z
Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.
Molecular and cellular biology 2005;25(1):185-96.
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2005: Sergeant John; Taylor Elaine; Palecek Jan; Fousteri Maria; Andrews Emily A; Sweeney Sara; Shinagawa Hideo; Watts Felicity Z; Lehmann Alan R
Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex.
Molecular and cellular biology 2005;25(1):172-84.
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2005: Ogi Tomoo; Kannouche Patricia; Lehmann Alan R
Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci.
Journal of cell science 2005;118(Pt 1):129-36.
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2005: Green Catherine M; Lehmann Alan R
Translesion synthesis and error-prone polymerases.
Advances in experimental medicine and biology 2005;570():199-223.
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2004: Tissier Agnès; Kannouche Patricia; Reck Marie-Pierre; Lehmann Alan R; Fuchs Robert P P; Cordonnier Agnès
Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein.
DNA repair 2004;3(11):1503-14.
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2004: Vidal Antonio E; Kannouche Patricia; Podust Vladimir N; Yang Wei; Lehmann Alan R; Woodgate Roger
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota.
The Journal of biological chemistry 2004;279(46):48360-8.
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2004: Shiloh Yosef; Lehmann Alan R
Maintaining integrity.
Nature cell biology 2004;6(10):923-8.
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2004: Kannouche Patricia L; Lehmann Alan R
Ubiquitination of PCNA and the polymerase switch in human cells.
Cell cycle (Georgetown, Tex.) 2004;3(8):1011-3.
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2004: Kannouche Patricia L; Wing Jonathan; Lehmann Alan R
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage.
Molecular cell 2004;14(4):491-500.
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2004: Vaisman Alexandra; Lehmann Alan R; Woodgate Roger
DNA polymerases eta and iota.
Advances in protein chemistry 2004;69():205-28.
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2003: Taylor Ewan R; Dornan Edward S; Boner Winifred; Connolly Julie A; McNair Shona; Kannouche Patricia; Lehmann A R; Morgan Iain M
The fidelity of HPV16 E1/E2-mediated DNA replication.
The Journal of biological chemistry 2003;278(52):52223-30.
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2003: Lehmann Alan R
DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy.
Biochimie 2003;85(11):1101-11.
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2003: Lehmann Alan R
Replication of damaged DNA.
Cell cycle (Georgetown, Tex.) 2003;2(4):300-2.
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2003: Stary Anne; Kannouche Patricia; Lehmann Alan R; Sarasin Alain
Role of DNA polymerase eta in the UV mutation spectrum in human cells.
The Journal of biological chemistry 2003;278(21):18767-75.
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2003: Kannouche Patricia; Fernández de Henestrosa Antonio R; Coull Barry; Vidal Antonio E; Gray Colin; Zicha Daniel; Woodgate Roger; Lehmann Alan R
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.
The EMBO journal 2003;22(5):1223-33.
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2002: Lehmann Alan R
Replication of damaged DNA in mammalian cells: new solutions to an old problem.
Mutation research 2002;509(1-2):23-34.
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2002: Kannouche Patricia; Fernández de Henestrosa Antonio R; Coull Barry; Vidal Antonio E; Gray Colin; Zicha Daniel; Woodgate Roger; Lehmann Alan R
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.
The EMBO journal 2002;21(22):6246-56.
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2002: Botta Elena; Nardo Tiziana; Lehmann Alan R; Egly Jean-Marc; Pedrini Antonia M; Stefanini Miria
Reduced level of the repair/transcription factor TFIIH in trichothiodystrophy.
Human molecular genetics 2002;11(23):2919-28.
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2002: Broughton Bernard C; Cordonnier Agnes; Kleijer Wim J; Jaspers Nicolaas G J; Fawcett Heather; Raams Anja; Garritsen Victor H; Stary Anne; Avril Marie-Françoise; Boudsocq Francois; Masutani Chikahide; Hanaoka Fumio; Fuchs Robert P; Sarasin Alain; Lehmann Alan R
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):815-20.
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2001: Viprakasit V; Gibbons R J; Broughton B C; Tolmie J L; Brown D; Lunt P; Winter R M; Marinoni S; Stefanini M; Brueton L; Lehmann A R; Higgs D R
Mutations in the general transcription factor TFIIH result in beta-thalassaemia in individuals with trichothiodystrophy.
Human molecular genetics 2001;10(24):2797-802.
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2001: Broughton B C; Berneburg M; Fawcett H; Taylor E M; Arlett C F; Nardo T; Stefanini M; Menefee E; Price V H; Queille S; Sarasin A; Bohnert E; Krutmann J; Davidson R; Kraemer K H; Lehmann A R
Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene.
Human molecular genetics 2001;10(22):2539-47.
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2001: Taylor E M; Moghraby J S; Lees J H; Smit B; Moens P B; Lehmann A R
Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex.
Molecular biology of the cell 2001;12(6):1583-94.
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2001: Zeng X; Winter D B; Kasmer C; Kraemer K H; Lehmann A R; Gearhart P J
DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes.
Nature immunology 2001;2(6):537-41.
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2001: Kannouche P; Broughton B C; Volker M; Hanaoka F; Mullenders L H; Lehmann A R
Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells.
Genes & development 2001;15(2):158-72.
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2001: Lehmann A R
The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases.
Genes & development 2001;15(1):15-23.
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2001: Berneburg M; Lehmann A R
Xeroderma pigmentosum and related disorders: defects in DNA repair and transcription.
Advances in genetics 2001;43():71-102.
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2000: Lehmann A R
Replication of UV-damaged DNA: new insights into links between DNA polymerases, mutagenesis and human disease.
Gene 2000;253(1):1-12.
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2000: Colella S; Nardo T; Botta E; Lehmann A R; Stefanini M
Identical mutations in the CSB gene associated with either Cockayne syndrome or the DeSanctis-cacchione variant of xeroderma pigmentosum.
Human molecular genetics 2000;9(8):1171-5.
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2000: de Klein A; Muijtjens M; van Os R; Verhoeven Y; Smit B; Carr A M; Lehmann A R; Hoeijmakers J H
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.
Current biology : CB 2000;10(8):479-82.
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2000: Chavanne F; Broughton B C; Pietra D; Nardo T; Browitt A; Lehmann A R; Stefanini M
Mutations in the XPC gene in families with xeroderma pigmentosum and consequences at the cell, protein, and transcript levels.
Cancer research 2000;60(7):1974-82.
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2000: Fousteri M I; Lehmann A R
A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein.
The EMBO journal 2000;19(7):1691-702.
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2000: Berneburg M; Lowe J E; Nardo T; Araújo S; Fousteri M I; Green M H; Krutmann J; Wood R D; Stefanini M; Lehmann A R
UV damage causes uncontrolled DNA breakage in cells from patients with combined features of XP-D and Cockayne syndrome.
The EMBO journal 2000;19(5):1157-66.
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2000: Berneburg M; Clingen P H; Harcourt S A; Lowe J E; Taylor E M; Green M H; Krutmann J; Arlett C F; Lehmann A R
The cancer-free phenotype in trichothiodystrophy is unrelated to its repair defect.
Cancer research 2000;60(2):431-8.
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2000: Monteiro C; Marcelino L A; Conde A R; Saraiva C; Giphart-Gassler M; De Nooij-van Dalen A G; Van Buuren-van Seggelen V; Van der Keur M; May C A; Cole J; Lehmann A R; Steinsgrimsdottir H; Beare D; Capulas E; Armour J A
Molecular methods for the detection of mutations.
Teratogenesis, carcinogenesis, and mutagenesis 2000;20(6):357-86.
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1999: McDonald J P; Rapic-Otrin V; Epstein J A; Broughton B C; Wang X; Lehmann A R; Wolgemuth D J; Woodgate R
Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta.
Genomics 1999;60(1):20-30.
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1999: Riballo E; Critchlow S E; Teo S H; Doherty A J; Priestley A; Broughton B; Kysela B; Beamish H; Plowman N; Arlett C F; Lehmann A R; Jackson S P; Jeggo P A
Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient.
Current biology : CB 1999;9(13):699-702.
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1999: van Hoffen A; Kalle W H; de Jong-Versteeg A; Lehmann A R; van Zeeland A A; Mullenders L H
Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription.
Nucleic acids research 1999;27(14):2898-904.
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1999: Colella S; Nardo T; Mallery D; Borrone C; Ricci R; Ruffa G; Lehmann A R; Stefanini M
Alterations in the CSB gene in three Italian patients with the severe form of Cockayne syndrome (CS) but without clinical photosensitivity.
Human molecular genetics 1999;8(5):935-41.
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1999: Cordonnier A M; Lehmann A R; Fuchs R P
Impaired translesion synthesis in xeroderma pigmentosum variant extracts.
Molecular and cellular biology 1999;19(3):2206-11.
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1998: Botta E; Nardo T; Broughton B C; Marinoni S; Lehmann A R; Stefanini M
Analysis of mutations in the XPD gene in Italian patients with trichothiodystrophy: site of mutation correlates with repair deficiency, but gene dosage appears to determine clinical severity.
American journal of human genetics 1998;63(4):1036-48.
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1998: Taylor E M; Lehmann A R
Conservation of eukaryotic DNA repair mechanisms.
International journal of radiation biology 1998;74(3):277-86.
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1998: Jeggo P A; Carr A M; Lehmann A R
Splitting the ATM: distinct repair and checkpoint defects in ataxia-telangiectasia.
Trends in genetics : TIG 1998;14(8):312-6.
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1998: de Boer J; de Wit J; van Steeg H; Berg R J; Morreau H; Visser P; Lehmann A R; Duran M; Hoeijmakers J H; Weeda G
A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy.
Molecular cell 1998;1(7):981-90.
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1998: Svetlova M P; Solovjeva L V; Nikiforov A A; Chagin V A; Lehmann A R; Tomilin N V
Staurosporine-sensitive protein phosphorylation is required for postreplication DNA repair in human cells.
FEBS letters 1998;428(1-2):23-6.
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1998: Lehmann A R
Dual functions of DNA repair genes: molecular, cellular, and clinical implications.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(2):146-55.
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1998: Mallery D L; Tanganelli B; Colella S; Steingrimsdottir H; van Gool A J; Troelstra C; Stefanini M; Lehmann A R
Molecular analysis of mutations in the CSB (ERCC6) gene in patients with Cockayne syndrome.
American journal of human genetics 1998;62(1):77-85.
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1997: Taylor E M; Broughton B C; Botta E; Stefanini M; Sarasin A; Jaspers N G; Fawcett H; Harcourt S A; Arlett C F; Lehmann A R
Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8658-63.
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1997: Ahrens C; Grewe M; Berneburg M; Grether-Beck S; Quilliet X; Mezzina M; Sarasin A; Lehmann A R; Arlett C F; Krutmann J
Photocarcinogenesis and inhibition of intercellular adhesion molecule 1 expression in cells of DNA-repair-defective individuals.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):6837-41.
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1997: Yonemasu R; McCready S J; Murray J M; Osman F; Takao M; Yamamoto K; Lehmann A R; Yasui A
Characterization of the alternative excision repair pathway of UV-damaged DNA in Schizosaccharomyces pombe.
Nucleic acids research 1997;25(8):1553-8.
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1997: Singleton B K; Priestley A; Steingrimsdottir H; Gell D; Blunt T; Jackson S P; Lehmann A R; Jeggo P A
Molecular and biochemical characterization of xrs mutants defective in Ku80.
Molecular and cellular biology 1997;17(3):1264-73.
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1997: McDaniel L D; Legerski R; Lehmann A R; Friedberg E C; Schultz R A
Confirmation of homozygosity for a single nucleotide substitution mutation in a Cockayne syndrome patient using monoallelic mutation analysis in somatic cell hybrids.
Human mutation 1997;10(4):317-21.
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1996: Lehmann A R; Bridges B A; Hanawalt P C; Johnson R T; Kanaar R; Krokan H E; Kyrtopoulos S; Lambert B; Melton D W; Moustacchi E; Natarajan A T; Radman M; Sarasin A; Seeberg E; Smerdon M J; Smith C A; Smith P J; Thacker J; Thomale J; Waters R; Weeda G; West S C; van Zeeland A A; Zdzienicka M Z
Workshop on processing of DNA damage.
Mutation research 1996;364(3):245-70.
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1996: Moriwaki S; Stefanini M; Lehmann A R; Hoeijmakers J H; Robbins J H; Rapin I; Botta E; Tanganelli B; Vermeulen W; Broughton B C; Kraemer K H
DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and cockayne syndrome resemble xeroderma pigmentosum cells.
The Journal of investigative dermatology 1996;107(4):647-53.
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1996: Blunt T; Gell D; Fox M; Taccioli G E; Lehmann A R; Jackson S P; Jeggo P A
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10285-90.
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1996: Lehmann A R
Molecular biology of DNA repair in the fission yeast Schizosaccharomyces pombe.
Mutation research 1996;363(3):147-61.
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1996: Steingrimsdottir H; Beare D; Cole J; Leal J F; Kostic T; Lopez-Barea J; Dorado G; Lehmann A R
Development of new molecular procedures for the detection of genetic alterations in man.
Mutation research 1996;353(1-2):109-21.
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1996: Stefanini M; Fawcett H; Botta E; Nardo T; Lehmann A R
Genetic analysis of twenty-two patients with Cockayne syndrome.
Human genetics 1996;97(4):418-23.
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1996: Broughton B C; Steingrimsdottir H; Lehmann A R
Five polymorphisms in the coding sequence of the xeroderma pigmentosum group D gene.
Mutation research 1996;362(2):209-11.
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1996: Takayama K; Salazar E P; Broughton B C; Lehmann A R; Sarasin A; Thompson L H; Weber C A
Defects in the DNA repair and transcription gene ERCC2(XPD) in trichothiodystrophy.
American journal of human genetics 1996;58(2):263-70.
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1996: Solov'eva L V; Svetlova M P; Hancock R; Whittle R; Lehmann A R; Bootsma D; Tomilin N V
[The dual function of the proliferating cell nuclear antigen (PCNA) in the response of human cells to UV damages]
Tsitologiia 1996;38(12):1294-302.
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1995: Griffiths D J; Barbet N C; McCready S; Lehmann A R; Carr A M
Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins.
The EMBO journal 1995;14(23):5812-23.
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1995: Lehmann A R; Walicka M; Griffiths D J; Murray J M; Watts F Z; McCready S; Carr A M
The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair.
Molecular and cellular biology 1995;15(12):7067-80.
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1995: Lehmann A R
Nucleotide excision repair and the link with transcription.
Trends in biochemical sciences 1995;20(10):402-5.
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1995: Lehmann A R; Carr A M
The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer.
Trends in genetics : TIG 1995;11(10):375-7.
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1995: Lynch S A; de Berker D; Lehmann A R; Pollitt R J; Reid M M; Lamb W H
Trichothiodystrophy with sideroblastic anaemia and developmental delay.
Archives of disease in childhood 1995;73(3):249-51.
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1995: Henning K A; Li L; Iyer N; McDaniel L D; Reagan M S; Legerski R; Schultz R A; Stefanini M; Lehmann A R; Mayne L V; Friedberg E C
The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH.
Cell 1995;82(4):555-64.
-
1995: Steingrimsdottir H; Beare D; Carr A M; Cole J; Lehmann A R
U.v.-hypermutability of xeroderma pigmentosum cells demonstrated with a DNA-based mutation system.
Oncogene 1995;10(10):2057-66.
-
1995: Sanford K K; Parshad R; Price F M; Tarone R E; Lehmann A R
G2 phase repair of X-ray-induced chromosomal DNA damage in trichothiodystrophy cells.
Mutation research 1995;346(2):107-14.
-
1995: Lehmann A R
Workshop on eukaryotic DNA repair genes and gene products.
Cancer research 1995;55(4):968-70.
-
1995: Lehmann A R
The molecular biology of nucleotide excision repair and double-strand break repair in eukaryotes.
Genetic engineering 1995;17():1-19.
-
1994: Jeggo P A; Carr A M; Lehmann A R
Cloning human DNA repair genes.
International journal of radiation biology 1994;66(5):573-7.
-
1994: Taccioli G E; Gottlieb T M; Blunt T; Priestley A; Demengeot J; Mizuta R; Lehmann A R; Alt F W; Jackson S P; Jeggo P A
Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination.
Science (New York, N.Y.) 1994;265(5177):1442-5.
-
1994: Mezzina M; Eveno E; Chevallier-Lagente O; Benoit A; Carreau M; Vermeulen W; Hoeijmakers J H; Stefanini M; Lehmann A R; Weber C A
Correction by the ERCC2 gene of UV sensitivity and repair deficiency phenotype in a subset of trichothiodystrophy cells.
Carcinogenesis 1994;15(8):1493-8.
-
1994: Murray J M; Tavassoli M; al-Harithy R; Sheldrick K S; Lehmann A R; Carr A M; Watts F Z
Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.
Molecular and cellular biology 1994;14(7):4878-88.
-
1994: Lehmann A R; Bootsma D; Clarkson S G; Cleaver J E; McAlpine P J; Tanaka K; Thompson L H; Wood R D
Nomenclature of human DNA repair genes.
Mutation research 1994;315(1):41-2.
-
1994: Broughton B C; Steingrimsdottir H; Weber C A; Lehmann A R
Mutations in the xeroderma pigmentosum group D DNA repair/transcription gene in patients with trichothiodystrophy.
Nature genetics 1994;7(2):189-94.
-
1994: Mondello C; Nardo T; Giliani S; Arrand J E; Weber C A; Lehmann A R; Nuzzo F; Stefanini M
Molecular analysis of the XP-D gene in Italian families with patients affected by trichothiodystrophy and xeroderma pigmentosum group D.
Mutation research 1994;314(2):159-65.
-
1994: al-Khodairy F; Fotou E; Sheldrick K S; Griffiths D J; Lehmann A R; Carr A M
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast.
Molecular biology of the cell 1994;5(2):147-60.
-
1994: Lehmann A R; Carr A M
DNA damage, repair and the cell cycle.
Trends in cell biology 1994;4(1):24-6.
-
1994: Tolmie J L; de Berker D; Dawber R; Galloway C; Gregory D W; Lehmann A R; McClure J; Pollitt R J; Stephenson J B
Syndromes associated with trichothiodystrophy.
Clinical dysmorphology 1994;3(1):1-14.
-
1994: Vermeulen W; van Vuuren A J; Chipoulet M; Schaeffer L; Appeldoorn E; Weeda G; Jaspers N G; Priestley A; Arlett C F; Lehmann A R
Three unusual repair deficiencies associated with transcription factor BTF2(TFIIH): evidence for the existence of a transcription syndrome.
Cold Spring Harbor symposia on quantitative biology 1994;59():317-29.
-
1993: Doe C L; Murray J M; Shayeghi M; Hoskins M; Lehmann A R; Carr A M; Watts F Z
Cloning and characterisation of the Schizosaccharomyces pombe rad8 gene, a member of the SNF2 helicase family.
Nucleic acids research 1993;21(25):5964-71.
-
1993: Lehmann A R
Duplicated region of sequence similarity to the human XRCC1 DNA repair gene in the Schizosaccharomyces pombe rad4/cut5 gene.
Nucleic acids research 1993;21(22):5274.
-
1993: McCready S; Carr A M; Lehmann A R
Repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in the fission yeast Schizosaccharomyces pombe.
Molecular microbiology 1993;10(4):885-90.
-
1993: Hafezparast M; Kaur G P; Zdzienicka M; Athwal R S; Lehmann A R; Jeggo P A
Subchromosomal localization of a gene (XRCC5) involved in double strand break repair to the region 2q34-36.
Somatic cell and molecular genetics 1993;19(5):413-21.
-
1993: Muris D F; Vreeken K; Carr A M; Broughton B C; Lehmann A R; Lohman P H; Pastink A
Cloning the RAD51 homologue of Schizosaccharomyces pombe.
Nucleic acids research 1993;21(19):4586-91.
-
1993: Lehmann A R; Thompson A F; Harcourt S A; Stefanini M; Norris P G
Cockayne's syndrome: correlation of clinical features with cellular sensitivity of RNA synthesis to UV irradiation.
Journal of medical genetics 1993;30(8):679-82.
-
1993: Stefanini M; Lagomarsini P; Giliani S; Nardo T; Botta E; Peserico A; Kleijer W J; Lehmann A R; Sarasin A
Genetic heterogeneity of the excision repair defect associated with trichothiodystrophy.
Carcinogenesis 1993;14(6):1101-5.
-
1993: Berth-Jones J; Cole J; Lehmann A R; Arlett C F; Graham-Brown R A
Xeroderma pigmentosum variant: 5 years of tumour suppression by etretinate.
Journal of the Royal Society of Medicine 1993;86(6):355-6.
-
1993: Steingrimsdottir H; Rowley G; Waugh A; Beare D; Ceccherini I; Cole J; Lehmann A R
Molecular analysis of mutations in the hprt gene in circulating lymphocytes from normal and DNA-repair-deficient donors.
Mutation research 1993;294(1):29-41.
-
1993: Carr A M; Sheldrick K S; Murray J M; al-Harithy R; Watts F Z; Lehmann A R
Evolutionary conservation of excision repair in Schizosaccharomyces pombe: evidence for a family of sequences related to the Saccharomyces cerevisiae RAD2 gene.
Nucleic acids research 1993;21(6):1345-9.
-
1993: Lindahl T; Prigent C; Barnes D E; Lehmann A R; Satoh M S; Roberts E; Nash R A; Robins P; Daly G
DNA joining in mammalian cells.
Cold Spring Harbor symposia on quantitative biology 1993;58():619-24.
-
1992: Carr A M; Green M H; Lehmann A R
Checkpoint policing by p53.
Nature 1992;359(6395):486-7.
-
1992: Webster A D; Barnes D E; Arlett C F; Lehmann A R; Lindahl T
Growth retardation and immunodeficiency in a patient with mutations in the DNA ligase I gene.
Lancet 1992;339(8808):1508-9.
-
1992: Murray J M; Doe C L; Schenk P; Carr A M; Lehmann A R; Watts F Z
Cloning and characterisation of the S. pombe rad15 gene, a homologue to the S. cerevisiae RAD3 and human ERCC2 genes.
Nucleic acids research 1992;20(11):2673-8.
-
1992: Barnes D E; Tomkinson A E; Lehmann A R; Webster A D; Lindahl T
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents.
Cell 1992;69(3):495-503.
-
1992: Timms A R; Steingrimsdottir H; Lehmann A R; Bridges B A
Mutant sequences in the rpsL gene of Escherichia coli B/r: mechanistic implications for spontaneous and ultraviolet light mutagenesis.
Molecular & general genetics : MGG 1992;232(1):89-96.
-
1992: Steingrimsdottir H; Rowley G; Dorado G; Cole J; Lehmann A R
Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene.
Nucleic acids research 1992;20(6):1201-8.
-
1992: Lehmann A R; Hoeijmakers J H; van Zeeland A A; Backendorf C M; Bridges B A; Collins A; Fuchs R P; Margison G P; Montesano R; Moustacchi E
Workshop on DNA repair.
Mutation research 1992;273(1):1-28.
-
1991: Fenech M; Carr A M; Murray J; Watts F Z; Lehmann A R
Cloning and characterization of the rad4 gene of Schizosaccharomyces pombe; a gene showing short regions of sequence similarity to the human XRCC1 gene.
Nucleic acids research 1991;19(24):6737-41.
-
1991: Lehmann A R; Carr A M; Watts F Z; Murray J M
DNA repair in the fission yeast, Schizosaccharomyces pombe.
Mutation research 1991;250(1-2):205-10.
-
1991: Anstey A V; Arlett C F; Cole J; Norris P G; Hamblin A S; Limb G A; Lehmann A R; Wilkinson J D; Turner M
Long-term survival and preservation of natural killer cell activity in a xeroderma pigmentosum patient with spontaneous regression and multiple deposits of malignant melanoma.
The British journal of dermatology 1991;125(3):272-8.
-
1991: Broughton B C; Barbet N; Murray J; Watts F Z; Koken M H; Lehmann A R; Carr A M
Assignment of ten DNA repair genes from Schizosaccharomyces pombe to chromosomal NotI restriction fragments.
Molecular & general genetics : MGG 1991;228(3):470-2.
-
1991: Murray J M; Carr A M; Lehmann A R; Watts F Z
Cloning and characterisation of the rad9 DNA repair gene from Schizosaccharomyces pombe.
Nucleic acids research 1991;19(13):3525-31.
-
1991: Norris P G; Arlett C F; Cole J; Lehmann A R; Hawk J L
Abnormal erythemal response and elevated T lymphocyte HRPT mutant frequency in Cockayne's syndrome.
The British journal of dermatology 1991;124(5):453-60.
-
1991: Muriel W J; Lamb J R; Lehmann A R
UV mutation spectra in cell lines from patients with Cockayne's syndrome and ataxia telangiectasia, using the shuttle vector pZ189.
Mutation research 1991;254(2):119-23.
-
1991: Dorado G; Steingrimsdottir H; Arlett C F; Lehmann A R
Molecular analysis of ultraviolet-induced mutations in a xeroderma pigmentosum cell line.
Journal of molecular biology 1991;217(2):217-22.
-
1990: Bridges B A; Carr A M; Lehmann A R
Possible methodologies for the detection and study of DNA sequence changes following mutagen exposure: magnetic enrichment in mutant DNA.
Mutagenesis 1990;5(6):523-4.
-
1990: Lehmann A R; Bridges B A
Sunlight-induced cancer: some new aspects and implications of the xeroderma pigmentosum model.
The British journal of dermatology 1990;122 Suppl 35():115-9.
-
1990: Lehmann A R; Norris P G
DNA repair deficient photodermatoses.
Seminars in dermatology 1990;9(1):55-62.
-
1990: Broughton B C; Lehmann A R; Harcourt S A; Arlett C F; Sarasin A; Kleijer W J; Beemer F A; Nairn R; Mitchell D L
Relationship between pyrimidine dimers, 6-4 photoproducts, repair synthesis and cell survival: studies using cells from patients with trichothiodystrophy.
Mutation research 1990;235(1):33-40.
-
1990: Norris P G; Limb G A; Hamblin A S; Lehmann A R; Arlett C F; Cole J; Waugh A P; Hawk J L
Immune function, mutant frequency, and cancer risk in the DNA repair defective genodermatoses xeroderma pigmentosum, Cockayne's syndrome, and trichothiodystrophy.
The Journal of investigative dermatology 1990;94(1):94-100.
-
1989: Lehmann A R
Trichothiodystrophy and the relationship between DNA repair and cancer.
BioEssays : news and reviews in molecular, cellular and developmental biology 1989;11(6):168-70.
-
1989: Lehmann A R; Jaspers N G; Gatti R A
Fourth International Workshop on Ataxia-Telangiectasia.
Cancer research 1989;49(21):6162-3.
-
1989: Lehmann A R; Norris P G
DNA repair and cancer: speculations based on studies with xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy.
Carcinogenesis 1989;10(8):1353-6.
-
1989: Lamb J R; Petit-Frère C; Broughton B C; Lehmann A R; Green M H
Inhibition of DNA replication by ionizing radiation is mediated by a trans-acting factor.
International journal of radiation biology 1989;56(2):125-30.
-
1989: Dean S W; Kincla L; Sykes H R; Lehmann A R; Wise I A
Instability of extrachromosomal cosmid DNA in SV40-transformed human (ataxia-telangiectasia) cells.
Experimental cell research 1989;183(2):473-83.
-
1989: Lehmann A R; Arlett C F; Harcourt S A; Steingrimsdottir H; Gebara M M
Mutagenic treatments result in inactivation of expression of a transfected bacterial gene integrated into a human cell line.
Mutation research 1989;220(2-3):255-62.
-
1988: Lehmann A R; Willis A E; Broughton B C; James M R; Steingrimsdottir H; Harcourt S A; Arlett C F; Lindahl T
Relation between the human fibroblast strain 46BR and cell lines representative of Bloom's syndrome.
Cancer research 1988;48(22):6343-7.
-
1988: Lehmann A R; Arlett C F; Broughton B C; Harcourt S A; Steingrimsdottir H; Stefanini M; Malcolm A; Taylor R; Natarajan A T; Green S
Trichothiodystrophy, a human DNA repair disorder with heterogeneity in the cellular response to ultraviolet light.
Cancer research 1988;48(21):6090-6.
-
1988: Dean S W; Sykes H R; Lehmann A R
Inactivation by nitrogen mustard of plasmids introduced into normal and Fanconi's anaemia cells.
Mutation research 1988;194(1):57-63.
-
1988: Mayne L V; Jones T; Dean S W; Harcourt S A; Lowe J E; Priestley A; Steingrimsdottir H; Sykes H; Green M H; Lehmann A R
SV 40-transformed normal and DNA-repair-deficient human fibroblasts can be transfected with high frequency but retain only limited amounts of integrated DNA.
Gene 1988;66(1):65-76.
-
1988: Parris C N; Arlett C F; Lehmann A R; Green M H; Masters J R
Differential sensitivities to gamma radiation of human bladder and testicular tumour cell lines.
International journal of radiation biology and related studies in physics, chemistry, and medicine 1988;53(4):599-608.
-
1987: Friedberg E C; Backendorf C; Burke J; Collins A; Grossman L; Hoeijmakers J H; Lehmann A R; Seeberg E; van der Schans G P; van Zeeland A A
Molecular aspects of DNA repair.
Mutation research 1987;184(2):67-86.
-
1987: Muriel W J; Cole J; Lehmann A R
Molecular analysis of ouabain-resistant mutants of the mouse lymphoma cell line L5178Y.
Mutagenesis 1987;2(5):383-9.
-
1987: Gebara M M; Drevon C; Harcourt S A; Steingrimsdottir H; James M R; Burke J F; Arlett C F; Lehmann A R
Inactivation of a transfected gene in human fibroblasts can occur by deletion, amplification, phenotypic switching, or methylation.
Molecular and cellular biology 1987;7(4):1459-64.
-
1987: Hilgers G; Abrahams P J; Schouten R; Cornelis J J; Lehmann A R; Van der Eb A J; Rommelaere J
[Cells of patients with ataxia telangiectasia show a normal capacity of radio-induced reactivation of damaged HSV-1 virus]
Comptes rendus des séances de la Société de biologie et de ses filiales 1987;181(4):432-8.
-
1987: Green M H; Lowe J E; Arlett C F; Harcourt S A; Burke J F; James M R; Lehmann A R; Povey S M
A gamma-ray-resistant derivative of an ataxia telangiectasia cell line obtained following DNA-mediated gene transfer.
Journal of cell science. Supplement 1987;6():127-37.
-
1986: Lehmann A R; Arlett C F; Burke J F; Green M H; James M R; Lowe J E
A derivative of an ataxia-telangiectasia (A-T) cell line with normal radiosensitivity but A-T-like inhibition of DNA synthesis.
International journal of radiation biology and related studies in physics, chemistry, and medicine 1986;49(4):639-43.
-
1985: Lehmann A R
Use of recombinant DNA techniques in cloning DNA repair genes and in the study of mutagenesis in mammalian cells.
Mutation research 1985;150(1-2):61-7.
-
1985: Poirier V; James M R; Arlett C F; Lehmann A R
NAD and the synthesis of (ADP-ribose)n in a human cell strain (46BR) hypersensitive to the lethal effects of 3-aminobenzamide.
Carcinogenesis 1985;6(6):837-41.
-
1985: Henderson L M; Arlett C F; Harcourt S A; Lehmann A R; Broughton B C
Cells from an immunodeficient patient (46BR) with a defect in DNA ligation are hypomutable but hypersensitive to the induction of sister chromatid exchanges.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(7):2044-8.
-
1985: Lehmann A R; Oomen A
Effect of DNA damage on the expression of the chloramphenicol acetyltransferase gene after transfection into diploid human fibroblasts.
Nucleic acids research 1985;13(6):2087-95.
-
1985: Lehmann A R; Francis A J; Giannelli F
Prenatal diagnosis of Cockayne's syndrome.
Lancet 1985;1(8427):486-8.
-
1985: Lehmann A R
Ageing, DNA repair of radiation damage and carcinogenesis: fact and fiction.
IARC scientific publications 1985;(58):203-13.
-
1984: Mayne L V; Broughton B C; Lehmann A R
The ultraviolet sensitivity of Cockayne syndrome cells is not a consequence of reduced cellular NAD content.
American journal of human genetics 1984;36(2):311-9.
-
1984: Lehmann A R; Broughton B C
Poly(ADP-ribosylation) reduces the steady-state level of breaks in DNA following treatment of human cells with alkylating agents.
Carcinogenesis 1984;5(1):117-9.
-
1983: Teo I A; Lehmann A R; Müller R; Rajewsky M F
Similar rate of O6-ethylguanine elimination from DNA in normal human fibroblast and xeroderma pigmentosum cell strains not transformed by SV40.
Carcinogenesis 1983;4(8):1075-7.
-
1983: Teo I A; Broughton B C; Day R S; James M R; Karran P; Mayne L V; Lehmann A R
A biochemical defect in the repair of alkylated DNA in cells from an immunodeficient patient (46BR).
Carcinogenesis 1983;4(5):559-64.
-
1982: Lehmann A R
Three complementation groups in Cockayne syndrome.
Mutation research 1982;106(2):347-56.
-
1982: Mayne L V; Lehmann A R; Waters R
Excision repair in Cockayne syndrome.
Mutation research 1982;106(1):179-89.
-
1982: James M R; Lehmann A R
Role of poly(adenosine diphosphate ribose) in deoxyribonucleic acid repair in human fibroblasts.
Biochemistry 1982;21(17):4007-13.
-
1982: Mayne L V; Lehmann A R
Failure of RNA synthesis to recover after UV irradiation: an early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum.
Cancer research 1982;42(4):1473-8.
-
1981: Lehmann A R
Cancer-associated human genetic diseases with defects in DNA repair.
Journal of cancer research and clinical oncology 1981;100(2):117-24.
-
1981: Lehmann A R; Karran P
DNA repair.
International review of cytology 1981;72():101-46.
-
1980: Arlett C F; Harcourt S A; Lehmann A R; Stevens S; Ferguson-Smith M A; Morley W N
Studies on a new case of xeroderma pigmentosum (XP3BR) from complementation group G with cellular sensitivity to ionizing radiation.
Carcinogenesis 1980;1(9):745-51.
-
1980: Lehmann A R
Early steps in excision repair.
Nature 1980;285(5767):614-5.
-
1980: Rogers A M; Hill R; Lehmann A R; Arlett C F; Burns V W
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
Mutation research 1980;69(1):139-48.
-
1980: Lehmann A R; Stevens S
A rapid procedure for measurement of DNA repair in human fibroblasts and for complementation analysis of xeroderma pigmentosum cells.
Mutation research 1980;69(1):177-90.
-
1979: Lehmann A R
The relationship between pyrimidine dimers and replicating DNA in UV-irradiated human fibroblasts.
Nucleic acids research 1979;7(7):1901-12.
-
1979: Lehmann A R; Kirk-Bell S; Mayne L
Abnormal kinetics of DNA synthesis in ultraviolet light-irradiated cells from patients with Cockayne's syndrome.
Cancer research 1979;39(10):4237-41.
-
1979: McGarva D; Doubleday O P; Lehmann A R; Bridges B A
Assays for the fidelity of DNA polymerases in cell-free extracts of Escherichia coli are complicated by contaminating nucleoside triphosphatases.
Biochimica et biophysica acta 1979;563(2):356-64.
-
1979: Arlett C F; Lehmann A R
The UV-response in repair-deficient human syndromes.
Acta biologica et medica Germanica 1979;38(9):1277-83.
-
1979: Lehmann A R; Stevens S
The response of ataxia telangiectasia cells to bleomycin.
Nucleic acids research 1979;6(5):1953-60.
-
1978: Lehmann A R; Kirk-Bell S
DNA-binding proteins in xeroderma pigmentosum fibroblasts.
Experimental cell research 1978;114(1):197-201.
-
1978: Arlett C F; Lehmann A R; Giannelli F; Ramsay C A
A human subject with a new defect in repair of ultraviolet damage.
The Journal of investigative dermatology 1978;70(4):173-7.
-
1978: Lehmann A R; Kirk-Bell S
Pyrimidine dimer sites associated with the daughter DNA strands in UV-irradiated human fibroblasts.
Photochemistry and photobiology 1978;27(3):297-307.
-
1978: Cramp W A; Köhnlein W; Lehmann A R
Biological functions of DNA and methods of testing.
Molecular biology, biochemistry, and biophysics 1978;27():255-60.
-
1978: Arlett C F; Lehmann A R
Human disorders showing increased sensitivity to the induction of genetic damage.
Annual review of genetics 1978;12():95-115.
-
1978: Lehmann A R
Repair processes for radiation-induced DNA damage.
Molecular biology, biochemistry, and biophysics 1978;27():312-34.
-
1977: Lehmann A R; Kirk-Bell S; Arlett C F; Harcourt S A; de Weerd-Kastelein E A; Keijzer W; Hall-Smith P
Repair of ultraviolet light damage in a variety of human fibroblast cell strains.
Cancer research 1977;37(3):904-10.
-
1977: Lehmann A R; Arlett C F
Human genetic disorders with defects in the repair of deoxyribonucleic acid [proceedings]
Biochemical Society transactions 1977;5(4):1199-203.
-
1977: Lehmann A R; Bridges B A
DNA repair.
Essays in biochemistry 1977;13():71-119.
-
1976: Arlett C F; Lehmann A R; Lohman P H; Paterson M C
Proceedings: Ataxia telangiectasia, radiosensitivity at the cellular and molecular level.
The British journal of radiology 1976;49(582):560-1.
-
1975: Arlett C F; Turnbull D; Harcourt S A; Lehmann A R; Colella C M
A comparison of the 8-azaguanine and ouabain-resistance systems for the selection of induced mutant Chinese hamster cells.
Mutation research 1975;33(2-3):261-78.
-
1975: Taylor A M; Harnden D G; Arlett C F; Harcourt S A; Lehmann A R; Stevens S; Bridges B A
Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity.
Nature 1975;258(5534):427-9.
-
1975: Nilsson K; Lehmann A R
The effect of methylated oxypurines on the size of newly-synthesized DNA and on the production of chromosome aberrations after UV irradiation in Chinese hamster cells.
Mutation research 1975;30(2):255-66.
-
1975: Lehmann A R; Stevens S
Postreplication repair of DNA in chick cells: studies using photoreactivation.
Biochimica et biophysica acta 1975;402(2):179-87.
-
1975: Lehmann A R; Kirk-Bell S; Arlett C F; Paterson M C; Lohman P H; de Weerd-Kastelein E A; Bootsma D
Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(1):219-23.
-
1975: Lehmann A R
Postreplication repair of DNA in UV-irradiated mammalian cells.
Basic life sciences 1975;5B():617-23.
-
1974: Lehmann A R
Postreplication repair of DNA in mammalian cells.
Life sciences 1974;15(12):2005-16.
-
1974: Lehmann A R
Postreplication repair of DNA in mammalian cells.
Life sciences 1974;15(12):2005-16.
-
1974: Green M H; Medcalf A S; Arlett C F; Harcourt S A; Lehmann A R
DNA strand breakage caused by dichlorvos, methyl methanesulphonate and iodoacetamide in Escherichia coli and cultured Chinese hamster cells.
Mutation research 1974;24(3):365-78.
-
1974: Lehmann A R; Kirk-Bell S
Effects of caffeine and theophylline on DNA synthesis in unirradiated and UV-irradiated mammalian cells.
Mutation research 1974;26(2):73-82.
-
1974: Lehmann A R; Kirk-Bell S; Shall S; Whish W J
The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.
Experimental cell research 1974;83(1):63-72.
-
1972: Lehmann A R
Post-replication repair of DNA in ultraviolet-irradiated mammalian cells. No gaps in DNA synthesized late after ultraviolet irradiation.
European journal of biochemistry / FEBS 1972;31(3):438-45.
-
1972: Lehmann A R
Effect of caffeine on DNA synthesis in mammalian cells.
Biophysical journal 1972;12(10):1316-25.
-
1972: Lehmann A R; Shall S
No inhibition of endogenous DNA polymerase by synthesis of poly (ADP-ribose) in nuclei from lymphoid cells.
FEBS letters 1972;26(1):181-4.
-
1972: Lehmann A R
Postreplication repair of DNA in ultraviolet-irradiated mammalian cells.
Journal of molecular biology 1972;66(3):319-37.
-
1971: Ormerod M G; Lehmann A R
Artefacts arising from the sedimentation of high molecular weight DNA on sucrose gradients.
Biochimica et biophysica acta 1971;247(3):369-72.
-
1971: Ormerod M G; Lehmann A R
The release of high molecular weight DNA from a mammalian cell (L-5178Y). Attachment of the DNA to the nuclear membrane.
Biochimica et biophysica acta 1971;228(2):331-43.
-
1970: Lehmann A R; Ormerod M G
Double-strand breaks in the DNA of a mammalian cell after x-irradiation.
Biochimica et biophysica acta 1970;217(2):268-77.
-
1970: Lehmann A R; Ormerod M G
The replication of DNA in murine lymphoma cells (L5178Y). I. Rate of replication.
Biochimica et biophysica acta 1970;204(1):128-43.
-
1969: Lehmann A R; Ormerod M G
Artefact in the measurement of the molecular weight of pulse labelled DNA.
Nature 1969;221(5185):1053-6.
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