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Steffen Mueller

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Publications

TOP 3
Nusrat Jahan; Eckard Wimmer; Steffen Mueller
Polypyrimidine Tract Binding Protein-1 (PTB1) Is a Determinant of the Tissue and Host Tropism of a Human Rhinovirus/Poliovirus Chimera PV1(RIPO).
Yutong Song; Charles B Ward; Bruce Futcher; Ying Liu; Steffen Mueller; Aniko V Paul; Steven Skiena; Eckard Wimmer
Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design.
Jeronimo Cello; Steffen Mueller
Production of infectious poliovirus from synthetic viral genomes.

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All Publications

2013: Nusrat Jahan; Eckard Wimmer; Steffen Mueller
Polypyrimidine Tract Binding Protein-1 (PTB1) Is a Determinant of the Tissue and Host Tropism of a Human Rhinovirus/Poliovirus Chimera PV1(RIPO).
PloS one 2013;8(4):e60791.
2012: Yutong Song; Charles B Ward; Bruce Futcher; Ying Liu; Steffen Mueller; Aniko V Paul; Steven Skiena; Eckard Wimmer
Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(36):14301-7.
2012: Jeronimo Cello; Steffen Mueller
Production of infectious poliovirus from synthetic viral genomes.
Methods in molecular biology (Clifton, N.J.) 2012;852():181-93.
2011: Varsha Sitaraman; Steven Skiena; Charles B Ward; Eckard Wimmer; Dmitri V Gnatenko; Patrick Hearing; Steffen Mueller; Wadie F Bahou
Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(34):14294-9.
2011: Nusrat Jahan; Eckard Wimmer; Steffen Mueller
A host-specific, temperature-sensitive translation defect determines the attenuation phenotype of a human rhinovirus/poliovirus chimera, PV1(RIPO).
Journal of virology 2011;85(14):7225-35.
2010: Steffen Mueller; J. Robert Coleman; Dimitris Papamichail; Charles B Ward; Anjaruwee Nimnual; Bruce Futcher; Steven Skiena; Eckard Wimmer
Live attenuated influenza virus vaccines by computer-aided rational design.
Nature biotechnology 2010;28(7):723-6.
2010: Ying Liu; Chunling Wang; Steffen Mueller; Aniko V Paul; Eckard Wimmer; Ping Jiang
Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis.
PLoS pathogens 2010;6(8):e1001066.
2009: Eckard Wimmer; Steffen Mueller; Terrence M Tumpey; Jeffery K Taubenberger
Synthetic viruses: a new opportunity to understand and prevent viral disease.
Nature biotechnology 2009;27(12):1163-72.
2009: Steffen Mueller; J. Robert Coleman; Eckard Wimmer
Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis.
Chemistry & biology 2009;16(3):337-47.
2008: Ping Zhang; Steffen Mueller; Marc C Morais; Carol M Bator; valorie bowman; Susan Hafenstein; Eckard Wimmer; Michael G Rossmann
Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18284-9.
2008: J. Robert Coleman; Dimitris Papamichail; Steven Skiena; Bruce Futcher; Eckard Wimmer; Steffen Mueller
Virus attenuation by genome-scale changes in codon pair bias.
Science (New York, N.Y.) 2008;320(5884):1784-7.
2007: Hidemi Toyoda; Jiang Yin; Steffen Mueller; Eckard Wimmer; Jeronimo Cello
Oncolytic treatment and cure of neuroblastoma by a novel attenuated poliovirus in a novel poliovirus-susceptible animal model.
Cancer research 2007;67(6):2857-64.
2006: Steffen Mueller; Dimitris Papamichail; J. Robert Coleman; Steven Skiena; Eckard Wimmer
Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity.
Journal of virology 2006;80(19):9687-96.
2006: Corey A Cohn; Steffen Mueller; Eckard Wimmer; Nicole Leifer; Steven Greenbaum; Daniel R Strongin; Martin A A Schoonen
Pyrite-induced hydroxyl radical formation and its effect on nucleic acids.
Geochemical transactions 2006;7():3.
2005: Steffen Mueller; Eckard Wimmer; Jeronimo Cello
Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event.
Virus research 2005;111(2):175-93.
2003: Steffen Mueller; Thomas A Rosenquist; Yoshimi Takai; Richard A Bronson; Eckard Wimmer
Loss of nectin-2 at Sertoli-spermatid junctions leads to male infertility and correlates with severe spermatozoan head and midpiece malformation, impaired binding to the zona pellucida, and oocyte penetration.
Biology of reproduction 2003;69(4):1330-40.
2003: Steffen Mueller; Eckard Wimmer
Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains.
The Journal of biological chemistry 2003;278(33):31251-60.
2003: Yongning He; Steffen Mueller; Paul R Chipman; Carol M Bator; Xiaozhong Peng; valorie bowman; Suchetana Mukhopadhyay; Eckard Wimmer; Richard J Kuhn; Michael G Rossmann
Complexes of poliovirus serotypes with their common cellular receptor, CD155.
Journal of virology 2003;77(8):4827-35.
2002: Akiko Iwasaki; Reinhold Welker; Steffen Mueller; Melissa M Linehan; Akio Nomoto; Eckard Wimmer
Immunofluorescence analysis of poliovirus receptor expression in Peyer's patches of humans, primates, and CD155 transgenic mice: implications for poliovirus infection.
The Journal of infectious diseases 2002;186(5):585-92.
2002: David J Solecki; Matthias Gromeier; Steffen Mueller; Günter Bernhardt; Eckard Wimmer
Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog.
The Journal of biological chemistry 2002;277(28):25697-702.
2002: Kumi Ozaki-Kuroda; Hiroyuki Nakanishi; Hiroshi Ohta; Hiromitsu Tanaka; Hidetake Kurihara; Steffen Mueller; Kenji Irie; Wataru Ikeda; Tatsuo Sakai; Eckard Wimmer; Yoshitake Nishimune; Yoshimi Takai
Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.
Current biology : CB 2002;12(13):1145-50.
2002: Steffen Mueller; Xuemei Cao; Reinhold Welker; Eckard Wimmer
Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis.
The Journal of biological chemistry 2002;277(10):7897-904.
2001: X Li; H H Lu; Steffen Mueller; Eckard Wimmer
The C-terminal residues of poliovirus proteinase 2A(pro) are critical for viral RNA replication but not for cis- or trans-proteolytic cleavage.
The Journal of general virology 2001;82(Pt 2):397-408.
2000: Yongning He; valorie bowman; Steffen Mueller; Carol M Bator; J Bella; X Peng; Timothy S Baker; Eckard Wimmer; Richard J Kuhn; Michael G Rossmann
Interaction of the poliovirus receptor with poliovirus.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):79-84.
1998: Steffen Mueller; Eckard Wimmer
Expression of foreign proteins by poliovirus polyprotein fusion: analysis of genetic stability reveals rapid deletions and formation of cardioviruslike open reading frames.
Journal of virology 1998;72(1):20-31.
1997: Matthias Gromeier; Steffen Mueller; David J Solecki; B Bossert; Günter Bernhardt; Eckard Wimmer
Determinants of poliovirus neurovirulence.
Journal of neurovirology 1997;3 Suppl 1():S35-8.