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João Calixto

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TOP 3
Israel Matos; Allisson Freire Bento; Rafaela F Claudino; Rodrigo Marcon; João B Calixto
Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: the relevance of cannabinoid system.
Rafael C Dutra; Daniela F P Leite; Marianne N Manjavachi; Rodrigo Marcon; João B Pesquero; Allisson F Bento; Maíra Assunção Bicca; João B Calixto
The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: Evidence for the involvement of astrocytes.
Flavia C Meotti; Alice F Viana; Stefânia Forner; Juliana F Lima-Garcia; João B Calixto
Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced haemorrhagic cystitis.

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All Publications

2013: Israel Matos; Allisson Freire Bento; Rafaela F Claudino; Rodrigo Marcon; João B Calixto
Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: the relevance of cannabinoid system.
Molecular immunology 2013;54(3-4):482-92.
2013: Rafael C Dutra; Daniela F P Leite; Marianne N Manjavachi; Rodrigo Marcon; João B Pesquero; Allisson F Bento; Maíra Assunção Bicca; João B Calixto
The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: Evidence for the involvement of astrocytes.
Neurobiology of disease 2013;54():82-93.
2013: Flavia C Meotti; Alice F Viana; Stefânia Forner; Juliana F Lima-Garcia; João B Calixto
Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced haemorrhagic cystitis.
Chemico-biological interactions 2013;203(2):440-7.
2013: Giselle F Passos; João B Calixto; Rodrigo Marcon; Rodrigo Medeiros; Andrey F Z Nascimento; Luiz F Pianowski
The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice.
European journal of pharmacology 2013;698(1-3):413-20.
2012: Allisson Freire Bento; Rafaela F Claudino; Maíra Cola; Rafael Cypriano Dutra; Daniela Ferraz Pereira Leite; Rodrigo Marcon; Alessandra Cadete Martini; João B Calixto
Evaluation of chemical mediators and cellular response during acute and chronic gut inflammatory response induced by dextran sodium sulfate in mice.
Biochemical pharmacology 2012;84(11):1459-69.
2012: Stefânia Forner; Janice Koepp; Alessandra C Martini; Rodrigo Medeiros; Edinéia L Andrade; Allisson F Bento; João B Calixto
Effects of kinin B(1) and B(2) receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats.
British journal of pharmacology 2012;167(8):1737-52.
2012: Fernanda L Basei; Daniela A Cabrini; Michael Bader; Maria Helena C Carvalho; Graziela S Ceravolo; Cláudia P Figueiredo; Stefânia Forner; Daniela B Hara; Rodrigo Medeiros; Andrey F Z Nascimento; João B Calixto
Endothelium dependent expression and underlying mechanisms of des-Arg⁹-bradykinin-induced B₁R-mediated vasoconstriction in rat portal vein.
Peptides 2012;37(2):216-24.
2012: Robson Costa; Marianne N Manjavachi; Emerson M Motta; Maíra Cola; João B Calixto
Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice.
Neuropharmacology 2012;63(5):798-805.
2012: Rafael Cypriano Dutra; Rodrigo Marcon; Flavia Carla Meotti; Ana Flavia Paszcuk; Luiz F Pianowski; Kathryn Ana Bortolini Simão da Silva; Allisson Freire Bento; João B Calixto
Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system.
Neuropharmacology 2012;63(4):593-605.
2012: Valnês S Rodrigues-Junior; Diógenes Santiago Santos; Cristopher Zandoná Schneider; Eduardo Henrique Silva Sousa; André Arigony Souto; Luiz Augusto Basso; João B Calixto; Luiz Gonzaga de França Lopes; André Dos Santos Junior; Anderson Jader Dos Santos; Maria M Campos
Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection.
International journal of antimicrobial agents 2012;40(2):182-5.
2012: Juliana Romanini; Eraldo L Batista; João B Calixto; Cláudia P Figueiredo; Paulo C Leal; Tânia R Mielcke; Fernanda Bueno Morrone; Maria M Campos
The role of CXCR2 chemokine receptors in the oral squamous cell carcinoma.
Investigational new drugs 2012;30(4):1371-8.
2012: Elizandra Braganhol; João B Calixto; Luis F Campesato; Maria M Campos; Angelica R Cappellari; Maria Isabel Edelweiss; Fernanda Bueno Morrone; Simon C Robson; Jean Sévigny; Márcia R Wink; Rafael F Zanin; Leticia S Bergamin; Andressa Bernardi; Ana Maria Oliveira Battastini
Overexpression of NTPDase2 in gliomas promotes systemic inflammation and pulmonary injury.
Purinergic signalling 2012;8(2):235-43.
2012: Rafael Cypriano Dutra; Rodrigo Marcon; Luiz F Pianowski; Paula Roberta de Cezaro de Souza; Allisson Freire Bento; Maíra Assunção Bicca; João B Calixto
Euphol prevents experimental autoimmune encephalomyelitis in mice: evidence for the underlying mechanisms.
Biochemical pharmacology 2012;83(4):531-42.
2012: E L Andrade; Flavia Carla Meotti; João B Calixto
TRPA1 antagonists as potential analgesic drugs.
Pharmacology & therapeutics 2012;133(2):189-204.
2012: Kathryn A B S da Silva; Marianne Neves Manjavachi; Ana Flavia Paszcuk; Marcos Pivatto; Claudio Viegas; Vanderlan S Bolzani; João B Calixto
Plant derived alkaloid (-)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models.
Neuropharmacology 2012;62(2):967-77.
2012: Manuella P Kaster; João B Calixto; Vinicius M Gadotti; Adair R S Santos; Ana Lúcia S Rodrigues
Depressive-like behavior induced by tumor necrosis factor-α in mice.
Neuropharmacology 2012;62(1):419-26.
2011: Daniel F Martins; Leidiane Mazzardo-Martins; Francisney P Nascimento; Breno Speckhann; Franciane Bobinski; Elisângela Bressan; João B Calixto; Eduardo Cargnin-Ferreira; Rafael C Dutra; Gisela A Favretto; Vinicius M Gadotti; Denise A N Lima; Adair R S Santos
Ankle joint mobilization reduces axonotmesis-induced neuropathic pain and glial activation in the spinal cord and enhances nerve regeneration in rats.
Pain 2011;152(11):2653-61.
2011: Vinícios T Boeira; João B Calixto; Maria M Campos; Maria Isabel Edelweiss; Carlos E Leite; André A Santos; Fernanda Bueno Morrone
Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse.
Naunyn-Schmiedeberg's archives of pharmacology 2011;384(3):265-75.
2011: Robson Costa; Rafael C Dutra; Fernanda R Malinsky; Marianne N Manjavachi; Emerson M Motta; João B Pesquero; Allisson F Bento; João B Calixto
Anti-nociceptive effect of kinin B₁ and B₂ receptor antagonists on peripheral neuropathy induced by paclitaxel in mice.
British journal of pharmacology 2011;164(2b):681-93.
2011: Allisson Freire Bento; Rafaela Franco Claudino; Rafael Cypriano Dutra; Rodrigo Marcon; João B Calixto
Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1957-69.
2011: Kathryn A B Simão da Silva; Allisson Freire Bento; Flavia Carla Meotti; Giselle F Passos; Ana Flavia Paszcuk; Eduardo S Silva; João B Calixto
Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice.
Pain 2011;152(8):1872-87.
2011: Alexandre P Rogerio; Edinéia L Andrade; João B Calixto
C-fibers, but not the transient potential receptor vanilloid 1 (TRPV1), play a role in experimental allergic airway inflammation.
European journal of pharmacology 2011;662(1-3):55-62.
2011: Edinéia Lemos Andrade; Stefânia Forner; Allisson Freire Bento; Danela Leite; Marcos Antonio Dias; Paulo César Leal; Janice Koepp; João B Calixto
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
American journal of physiology. Renal physiology 2011;300(5):F1223-34.
2011: Allisson Freire Bento; Rodrigo Marcon; Rafael Cypriano Dutra; Rafaela Franco Claudino; Maíra Cola; Daniela Ferraz Pereira Leite; João B Calixto
β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway.
The American journal of pathology 2011;178(3):1153-66.
2011: Rafael C Dutra; Cláudia P Figueiredo; Danela Leite; Marianne N Manjavachi; Eliziane S Patrício; João B Pesquero; Allisson F Bento; João B Calixto
The role of kinin receptors in preventing neuroinflammation and its clinical severity during experimental autoimmune encephalomyelitis in mice.
PloS one 2011;6(11):e27875.
2011: Rafael C Dutra; Rodrigo Marcon; Luiz F Pianowski; Eder C Schmidt; Allisson F Bento; Zenilda L Bouzon; Rafaela F Claudino; João B Calixto
Preventive and therapeutic euphol treatment attenuates experimental colitis in mice.
PloS one 2011;6(11):e27122.
2011: Ana Flavia Paszcuk; Nara L M Quintão; Maria M Campos; Kathryn A B S da Silva; Rafael C Dutra; João B Calixto
Cannabinoid agonists inhibit neuropathic pain induced by brachial plexus avulsion in mice by affecting glial cells and MAP kinases.
PloS one 2011;6(9):e24034.
2011: Cláudia P Figueiredo; Maíra A Bicca; Alexandra Latini; Rui D S Prediger; Rodrigo Medeiros; João B Calixto
Folic acid plus α-tocopherol mitigates amyloid-β-induced neurotoxicity through modulation of mitochondrial complexes activity.
Journal of Alzheimer's disease : JAD 2011;24(1):61-75.
2011: Alice F Viana; Maria M Campos; Paulo C Leal; Izaque S Maciel; Emerson M Motta; Luiz Pianowski; João B Calixto
Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on Its Dopaminergic Effects.
Evidence-based complementary and alternative medicine : eCAM 2011;2011():120820.
2010: André A Santos; Paulo C Leal; Maria I A Edelweiss; Tiago Giuliani Lopes; João B Calixto; Fernanda Bueno Morrone; Maria M Campos
Effects of the compounds MV8608 and MV8612 obtained from Mandevilla velutina in the model of hemorrhagic cystitis induced by cyclophosphamide in rats.
Naunyn-Schmiedeberg's archives of pharmacology 2010;382(5-6):399-407.
2010: Marianne Neves Manjavachi; Emerson Marcelo Motta; Denise Marotta; Daniela Ferraz Pereira Leite; João B Calixto
Mechanisms involved in IL-6-induced muscular mechanical hyperalgesia in mice.
Pain 2010;151(2):345-55.
2010: Andressa Bernardi; Rudimar Luiz Frozza; Ana Paula Horn; Maria Martha Campos; João B Calixto; Christianne Salbego; Adriana Pohlmann; Sílvia S Guterres; Ana Maria Oliveira Battastini
Protective effects of indomethacin-loaded nanocapsules against oxygen-glucose deprivation in organotypic hippocampal slice cultures: involvement of neuroinflammation.
Neurochemistry international 2010;57(6):629-36.
2010: Rodrigo Medeiros; Cláudia P Figueiredo; Pablo Pandolfo; Filipe S Duarte; Rui D S Prediger; Giselle F Passos; João B Calixto
The role of TNF-alpha signaling pathway on COX-2 upregulation and cognitive decline induced by beta-amyloid peptide.
Behavioural brain research 2010;209(1):165-73.
2010: TB Nguelefack; Rafael C Dutra; Ana F Paszcuk; Edinéia L Andrade; Léon A Tapondjou; João B Calixto
Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation.
Journal of ethnopharmacology 2010;128(3):567-74.
2010: Alexandre P Rogerio; Cristiana L Dora; Edinéia L Andrade; Juliana S Chaves; Luis F C Silva; Elenara Lemos-Senna; João B Calixto
Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice.
Pharmacological research : the official journal of the Italian Pharmacological Society 2010;61(4):288-97.
2010: Diogo Santos M da Costa; Flavia Carla Meotti; Edinéia Lemos Andrade; Paulo César Leal; Emerson Marcelo Motta; João B Calixto
The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation.
Pain 2010;148(3):431-7.
2010: Giselle F Passos; Cláudia P Figueiredo; Rui D S Prediger; Kathryn A B S Silva; Jarbas M Siqueira; Filipe S Duarte; Paulo C Leal; Rodrigo Medeiros; João B Calixto
Involvement of phosphoinositide 3-kinase gamma in the neuro-inflammatory response and cognitive impairments induced by beta-amyloid 1-40 peptide in mice.
Brain, behavior, and immunity 2010;24(3):493-501.
2010: Robson Costa; Marianne N Manjavachi; Emerson M Motta; Denise Marotta; Luiz Juliano; Hugo A Torres; João B Pesquero; João B Calixto
The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase-activated receptor-2 agonists in mice.
British journal of pharmacology 2010;159(4):888-97.
2010: Alice F Viana; Izaque S Maciel; Fabiana N Dornelles; Claudia P Figueiredo; Jarbas M Siqueira; Maria M Campos; João B Calixto
Kinin B1 receptors mediate depression-like behavior response in stressed mice treated with systemic E. coli lipopolysaccharide.
Journal of neuroinflammation 2010;7():98.
2010: Marianne N Manjavachi; Nara L M Quintão; Maria Martha Campos; Isa K Deschamps; Rosendo A Yunes; Ricardo J Nunes; Paulo C Leal; João B Calixto
The effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice.
European journal of pain (London, England) 2010;14(1):23-31.
2009: Giselle Fazzioni Passos; Cláudia Pinto Figueiredo; Rui Daniel Schröder Prediger; Pablo Pandolfo; Filipe Silveira Duarte; Rodrigo Medeiros; João B Calixto
Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide.
The American journal of pathology 2009;175(4):1586-97.
2009: Alexandre P Rogerio; Edinéia L Andrade; Danela Leite; Cláudia P Figueiredo; João B Calixto
Preventive and therapeutic anti-inflammatory properties of the sesquiterpene alpha-humulene in experimental airways allergic inflammation.
British journal of pharmacology 2009;158(4):1074-87.
2009: Andressa Bernardi; A C C V Zilberstein; E Jäger; M M Campos; Fernanda Bueno Morrone; João B Calixto; Adriana Pohlmann; Sílvia S Guterres; Ana Maria Oliveira Battastini
Effects of indomethacin-loaded nanocapsules in experimental models of inflammation in rats.
British journal of pharmacology 2009;158(4):1104-11.
2009: Fabiana N Dornelles; Diógenes S Santos; Thomas E Van Dyke; João B Calixto; Eraldo L Batista; Maria M Campos
In vivo up-regulation of kinin B1 receptors after treatment with Porphyromonas gingivalis lipopolysaccharide in rat paw.
The Journal of pharmacology and experimental therapeutics 2009;330(3):756-63.
2009: Rodrigo Medeiros; Cláudia P Figueiredo; Giselle F Passos; João B Calixto
Reduced skin inflammatory response in mice lacking inducible nitric oxide synthase.
Biochemical pharmacology 2009;78(4):390-5.
2009: Anelize S Fogo; Eliane Antonioli; João B Calixto; Alexandre H Campos
Tormentic acid reduces vascular smooth muscle cell proliferation and survival.
European journal of pharmacology 2009;615(1-3):50-4.
2009: C E Vitor; Cláudia P Figueiredo; D B Hara; A F Bento; Tania Mazzuco; João B Calixto
Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes, alpha- and beta-amyrin, in a mouse model of colitis.
British journal of pharmacology 2009;157(6):1034-44.
2009: Denise M Marotta; Robson Costa; Emerson M Motta; Elizabeth S Fernandes; Rodrigo Medeiros; Nara L M Quintão; Maria M Campos; João B Calixto
Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw.
Biochemical pharmacology 2009;77(7):1223-35.
2008: Juliana Siqueira Chaves; Paulo César Leal; Luis Pianowisky; João B Calixto
Pharmacokinetics and tissue distribution of the sesquiterpene alpha-humulene in mice.
Planta medica 2008;74(14):1678-83.
2008: Allisson Freire Bento; Danela Leite; Rafaela Franco Claudino; Daniela Balz Hara; Paulo César Leal; João B Calixto
The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice.
Journal of leukocyte biology 2008;84(4):1213-21.
2008: Candida Kassuya; Alexandre P Rogerio; João B Calixto
The role of ET(A) and ET(B) receptor antagonists in acute and allergic inflammation in mice.
Peptides 2008;29(8):1329-37.
2008: D B Hara; Danela Leite; Elizabeth S Fernandes; Giselle F Passos; A O Guimarães; João B Pesquero; Maria M Campos; João B Calixto
The relevance of kinin B1 receptor upregulation in a mouse model of colitis.
British journal of pharmacology 2008;154(6):1276-86.
2008: R Costa; Denise Marotta; M N Manjavachi; Elizabeth S Fernandes; J F Lima-Garcia; Ana Flavia Paszcuk; Nara L M Quintão; L Juliano; S D Brain; João B Calixto
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.
British journal of pharmacology 2008;154(5):1094-103.
2008: Rodrigo Medeiros; Gustavo Büchele Rodrigues; Cláudia P Figueiredo; Eduardo B Rodrigues; Astor Grumman; Octávio Menezes-de-Lima; Giselle F Passos; João B Calixto
Molecular mechanisms of topical anti-inflammatory effects of lipoxin A(4) in endotoxin-induced uveitis.
Molecular pharmacology 2008;74(1):154-61.
2008: Nara L M Quintão; Adair R S Santos; Maria M Campos; João B Calixto
The role of neurotrophic factors in genesis and maintenance of mechanical hypernociception after brachial plexus avulsion in mice.
Pain 2008;136(1-2):125-33.
2008: Mauro Schneider Oliveira; Ana Flávia Furian; L M Rambo; L R Ribeiro; Luiz Fernando Freire Royes; Juliano Ferreira; João B Calixto; Carlos Fernando Mello
Modulation of pentylenetetrazol-induced seizures by prostaglandin E2 receptors.
Neuroscience 2008;152(4):1110-8.
2008: Nara L M Quintão; Juliano Ferreira; Alessandra Beirith; Maria M Campos; João B Calixto
Evaluation of the effects of the herbal product Catuama in inflammatory and neuropathic models of nociception in rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2008;15(4):245-52.
2008: E L Andrade; A P Luiz; Juliano Ferreira; João B Calixto
Pronociceptive response elicited by TRPA1 receptor activation in mice.
Neuroscience 2008;152(2):511-20.
2008: Nara L M Quintão; Giselle F Passos; Rodrigo Medeiros; Ana Flavia Paszcuk; Fabiana L Motta; João B Pesquero; Maria M Campos; João B Calixto
Neuropathic pain-like behavior after brachial plexus avulsion in mice: the relevance of kinin B1 and B2 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(11):2856-63.
2008: Juliano Ferreira; Karen M Trichês; Rodrigo Medeiros; Daniela Almeida Cabrini; Marcelo A S Mori; João B Pesquero; Michael Bader; João B Calixto
The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice.
Neuropharmacology 2008;54(3):597-604.
2008: Ana Flavia Paszcuk; Nara L M Quintão; Elizabeth S Fernandes; Luiz Juliano; Kevin Chapman; Patricia Andrade-Gordon; Maria M Campos; Nathalie Vergnolle; João B Calixto
Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw.
European journal of pharmacology 2008;581(1-2):204-15.
2008: Rui D S Prediger; Rodrigo Medeiros; Pablo Pandolfo; Filipe S Duarte; Giselle F Passos; J B Pesquero; Maria M Campos; João B Calixto; Reinaldo N Takahashi
Genetic deletion or antagonism of kinin B(1) and B(2) receptors improves cognitive deficits in a mouse model of Alzheimer's disease.
Neuroscience 2008;151(3):631-43.
2008: Louise Domeneghini Chiaradia; Rodrigo dos Santos; Carlos Eduardo Vitor; André Alexandre Vieira; Paulo Leal; Ricardo J Nunes; João B Calixto; Rosendo A Yunes
Synthesis and pharmacological activity of chalcones derived from 2,4,6-trimethoxyacetophenone in RAW 264.7 cells stimulated by LPS: quantitative structure-activity relationships.
Bioorganic & medicinal chemistry 2008;16(2):658-67.
2007: Edinéia Lemos Andrade; Juliano Ferreira; Adair R S Santos; João B Calixto
Pharmacological analysis of paregoric elixir and its constituents: in vitro and in vivo studies.
Journal of ethnopharmacology 2007;114(2):218-26.
2007: Lucia Helena Martini; Fernanda Jung; Félix A Soares; Liane N Rotta; Deusa Vendite; Marcos E S Frizzo; Rosendo A Yunes; João B Calixto; Susana Wofchuk; Diogo O Souza
Naturally occurring compounds affect glutamatergic neurotransmission in rat brain.
Neurochemical research 2007;32(11):1950-6.
2007: Roselei Fachinetto; Jardel G Villarinho; Caroline Wagner; Romaiana P Pereira; Daiana Silva Avila; Marilise E Burger; João B Calixto; João B T Rocha; Juliano Ferreira
Valeriana officinalis does not alter the orofacial dyskinesia induced by haloperidol in rats: role of dopamine transporter.
Progress in neuro-psychopharmacology & biological psychiatry 2007;31(7):1478-86.
2007: Roselei Fachinetto; Jardel G Villarinho; Caroline Wagner; Romaiana P Pereira; Robson Luiz Puntel; Marcio W Paixão; Antonio L Braga; João B Calixto; João B T Rocha; Juliano Ferreira
Diphenyl diselenide decreases the prevalence of vacuous chewing movements induced by fluphenazine in rats.
Psychopharmacology 2007;194(3):423-32.
2007: Danela Leite; Juliana Echevarria-Lima; Samira Cardoso Ferreira; João B Calixto; Vivian M Rumjanek
ABCC transporter inhibition reduces zymosan-induced peritonitis.
Journal of leukocyte biology 2007;82(3):630-7.
2007: Elizabeth S Fernandes; Giselle F Passos; Rodrigo Medeiros; Fernanda M da Cunha; Juliano Ferreira; Maria M Campos; Luiz F Pianowski; João B Calixto
Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea.
European journal of pharmacology 2007;569(3):228-36.
2007: Alexandre P Rogerio; Cristina R Cardoso; Caroline Fontanari; Maria A Souza; Sandra R Afonso-Cardoso; Erika Vg Silva; Natalia S Koyama; Fernanda L Basei; Edson G Soares; João B Calixto; Sean R Stowell; Marcelo Dias-Baruffi; Lúcia H Faccioli
Anti-asthmatic potential of a D-galactose-binding lectin from Synadenium carinatum latex.
Glycobiology 2007;17(8):795-804.
2007: G D Dalmolin; C R Silva; N A V Bellé; Maribel Antonello Rubin; Carlos Fernando Mello; João B Calixto; J Ferreira
Bradykinin into amygdala induces thermal hyperalgesia in rats.
Neuropeptides 2007;41(4):263-70.
2007: Ana Flavia Paszcuk; Vinicius M Gadotti; Daiane Tibola; Nara L M Quintão; Ana Lúcia S Rodrigues; João B Calixto; Adair R S Santos
Anti-hypernociceptive properties of agmatine in persistent inflammatory and neuropathic models of pain in mice.
Brain research 2007;1159():124-33.
2007: M F P Werner; Candida Kassuya; Juliano Ferreira; Aleksander Roberto Zampronio; João B Calixto; Giles A Rae
Peripheral kinin B(1) and B(2) receptor-operated mechanisms are implicated in neuropathic nociception induced by spinal nerve ligation in rats.
Neuropharmacology 2007;53(1):48-57.
2007: Rodrigo Medeiros; Giselle F Passos; C E Vitor; Janice Koepp; Tania Mazzuco; Luiz F Pianowski; Maria M Campos; João B Calixto
Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw.
British journal of pharmacology 2007;151(5):618-27.
2007: Daniela Balz Hara; Elizabeth S Fernandes; Maria M Campos; João B Calixto
Pharmacological and biochemical characterization of bradykinin B2 receptors in the mouse colon: influence of the TNBS-induced colitis.
Regulatory peptides 2007;141(1-3):25-34.
2007: Rodrigo Medeiros; Rui D S Prediger; Giselle F Passos; Pablo Pandolfo; Filipe S Duarte; Jeferson Luis Franco; Alcir L Dafre; Gabriella Di Giunta; Cláudia P Figueiredo; Reinaldo N Takahashi; Maria M Campos; João B Calixto
Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(20):5394-404.
2007: Rodrigo Medeiros; Michel F Otuki; Maria Christina W Avellar; João B Calixto
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
European journal of pharmacology 2007;559(2-3):227-35.
2007: Giselle F Passos; Elizabeth S Fernandes; Fernanda M da Cunha; Juliano Ferreira; Luiz F Pianowski; Maria M Campos; João B Calixto
Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea.
Journal of ethnopharmacology 2007;110(2):323-33.
2007: Carolina D Duarte; Jorge L M Tributino; Daniel I Lacerda; Marina V Martins; Magna S Alexandre-Moreira; Fernando Dutra; Etelvino J H Bechara; Francine S De-Paula; Marília O F Goulart; Juliano Ferreira; João B Calixto; Marise P Nunes; Alvaro Luiz Bertho; Ana L P Miranda; Eliezer J Barreiro; Carlos A M Fraga
Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors.
Bioorganic & medicinal chemistry 2007;15(6):2421-33.
2007: Candida Kassuya; Juliano Ferreira; Rafaela F Claudino; João B Calixto
Intraplantar PGE2 causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases.
British journal of pharmacology 2007;150(6):727-37.
2007: Gustavo Büchele Rodrigues; Giselle F Passos; Gabriella Di Giunta; Cláudia P Figueiredo; Eduardo B Rodrigues; Astor Grumman; Rodrigo Medeiros; João B Calixto
Preventive and therapeutic anti-inflammatory effects of systemic and topical thalidomide on endotoxin-induced uveitis in rats.
Experimental eye research 2007;84(3):553-60.
2007: Danela Leite; Juliana Echevarria-Lima; João B Calixto; Vivian M Rumjanek
Multidrug resistance related protein (ABCC1) and its role on nitrite production by the murine macrophage cell line RAW 264.7.
Biochemical pharmacology 2007;73(5):665-74.
2007: Rui D S Prediger; Jeferson Luis Franco; Pablo Pandolfo; Rodrigo Medeiros; Filipe S Duarte; Gabriella Di Giunta; Cláudia P Figueiredo; Marcelo Farina; João B Calixto; Reinaldo N Takahashi; Alcir L Dafre
Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response.
Behavioural brain research 2007;177(2):205-13.
2006: Maria M Campos; Paulo Leal; Rosendo A Yunes; João B Calixto
Non-peptide antagonists for kinin B1 receptors: new insights into their therapeutic potential for the management of inflammation and pain.
Trends in pharmacological sciences 2006;27(12):646-51.
2006: Danela Leite; Candida Kassuya; Tania Mazzuco; Aline Silvestre; Lucilia V de Melo; Vera Lúcia G Rehder; Vivian M Rumjanek; João B Calixto
The cytotoxic effect and the multidrug resistance reversing action of lignans from Phyllanthus amarus.
Planta medica 2006;72(15):1353-8.
2006: Michela Mantovani; Manuella P Kaster; Roberto Pertile; João B Calixto; Ana Lúcia S Rodrigues; Adair R S Santos
Mechanisms involved in the antinociception caused by melatonin in mice.
Journal of pineal research 2006;41(4):382-9.
2006: Robson Costa; Elizabeth S Fernandes; Octávio Menezes-de-Lima; Maria M Campos; João B Calixto
Effect of novel selective non-peptide kinin B(1) receptor antagonists on mouse pleurisy induced by carrageenan.
Peptides 2006;27(11):2967-75.
2006: Valdir F Veiga Junior; Luciano Zunino; Maria Lúcia Patitucci; Angelo C Pinto; João B Calixto
The inhibition of paw oedema formation caused by the oil of Copaifera multijuga Hayne and its fractions.
The Journal of pharmacy and pharmacology 2006;58(10):1405-10.
2006: Candida Kassuya; Aline Silvestre; Octávio Menezes-de-Lima; Denise Marotta; Vera Lúcia G Rehder; João B Calixto
Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor.
European journal of pharmacology 2006;546(1-3):182-8.
2006: Wilian M Mattos; Maria M Campos; Elizabeth S Fernandes; Graziela P Richetti; Rivaldo Niero; Rosendo A Yunes; João B Calixto
Anti-edematogenic effects of velutinol A isolated from Mandevilla velutina: evidence for a selective inhibition of kinin B1 receptor-mediated responses.
Regulatory peptides 2006;136(1-3):98-104.
2006: Octávio Menezes-de-Lima; Candida Kassuya; Andrey F Z Nascimento; M G M O Henriques; João B Calixto
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
Prostaglandins & other lipid mediators 2006;80(3-4):123-35.
2006: Rafaela F Claudino; Candida Kassuya; Juliano Ferreira; João B Calixto
Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema.
The Journal of pharmacology and experimental therapeutics 2006;318(2):611-8.
2006: Ana C C Rocha; Elizabeth S Fernandes; Nara L M Quintão; Maria M Campos; João B Calixto
Relevance of tumour necrosis factor-alpha for the inflammatory and nociceptive responses evoked by carrageenan in the mouse paw.
British journal of pharmacology 2006;148(5):688-95.
2006: Edinéia Lemos Andrade; Juliano Ferreira; Eunice André; João B Calixto
Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder.
Biochemical pharmacology 2006;72(1):104-14.
2006: Vinicius M Gadotti; Daiane Tibola; Ana Flavia Paszcuk; Ana Lúcia S Rodrigues; João B Calixto; Adair R S Santos
Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice.
Brain research 2006;1093(1):116-22.
2006: Emerson Marcelo Motta; João B Calixto; Giles A Rae
Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):1141-5.
2006: Mariem El Sayah; Rodrigo Medeiros; Elizabeth S Fernandes; Maria M Campos; João B Calixto
Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro.
Molecular pharmacology 2006;69(5):1701-8.
2006: Eunice André; Barbara Campi; Marcello Trevisani; Juliano Ferreira; Angela Malheiros; Rosendo A Yunes; João B Calixto; Pierangelo Geppetti
Pharmacological characterisation of the plant sesquiterpenes polygodial and drimanial as vanilloid receptor agonists.
Biochemical pharmacology 2006;71(8):1248-54.
2006: Wilian M Mattos; Juliano Ferreira; Graziela P Richetti; Rivaldo Niero; Rosendo A Yunes; João B Calixto
Antinociceptive properties produced by the pregnane compound velutinol A isolated from Mandevilla velutina.
Neuropeptides 2006;40(2):125-32.
2006: Nara L M Quintão; Daniela Balz; Adair R S Santos; Maria M Campos; João B Calixto
Long-lasting neuropathic pain induced by brachial plexus injury in mice: Role triggered by the pro-inflammatory cytokine, tumour necrosis factor alpha.
Neuropharmacology 2006;50(5):614-20.
2006: Lucia Helena Martini; Lucas Cereser; Isaac Zanonato Junior; Fluvia Melina Alves Jardim; Deusa Vendite; Marcos E S Frizzo; Rosendo A Yunes; João B Calixto; Susana Wofchuk; Diogo O Souza
The sesquiterpenes polygodial and drimanial in vitro affect glutamatergic transport in rat brain.
Neurochemical research 2006;31(3):431-8.
2006: Danela Leite; Juliana Echevarria-Lima; Leonardo T Salgado; M A M Capella; João B Calixto; Vivian M Rumjanek
In vivo and in vitro modulation of MDR molecules in murine thymocytes.
International immunopharmacology 2006;6(2):204-15.
2006: Flavia Carla Meotti; Ana Paula Luiz; Moacir Geraldo Pizzolatti; Candida Kassuya; João B Calixto; Adair R S Santos
Analysis of the antinociceptive effect of the flavonoid myricitrin: evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways.
The Journal of pharmacology and experimental therapeutics 2006;316(2):789-96.
2005: Nara L M Quintão; Rodrigo Medeiros; Adair R S Santos; Maria M Campos; João B Calixto
The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice.
Anesthesia and analgesia 2005;101(6):1763-9.
2005: Luiz Augusto Basso; Luiz Hildebrando Pereira da Silva; Arthur G Fett-Neto; Walter Filgueira de Azevedo; Icaro de Souza Moreira; Mario Palma; João B Calixto; Spartaco Astolfi-Filho; Ricardo Ribeiro dos Santos; Milena B P Soares; Diogenes Santos
The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases--a review.
Memórias do Instituto Oswaldo Cruz 2005;100(6):475-506.
2005: Ana C C Rocha; Elizabeth S Fernandes; Giselle F Passos; João B Calixto; Maria M Campos
Assessment of TNFalpha contribution to the functional up-regulation of kinin B(1) receptors in the mouse paw after treatment with LPS.
International immunopharmacology 2005;5(11):1593-600.
2005: Maria M Campos; Elizabeth S Fernandes; Juliano Ferreira; Adair R S Santos; João B Calixto
Antidepressant-like effects of Trichilia catigua (Catuaba) extract: evidence for dopaminergic-mediated mechanisms.
Psychopharmacology 2005;182(1):45-53.
2005: Juliano Ferreira; Karen M Trichês; Rodrigo Medeiros; João B Calixto
Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice.
Pain 2005;117(1-2):171-81.
2005: Elizabeth S Fernandes; Giselle F Passos; Maria M Campos; Glória E P de Souza; Juliana F Fittipaldi; Jorge L Pesquero; Mauro Teixeira; João B Calixto
Cytokines and neutrophils as important mediators of platelet-activating factor-induced kinin B1 receptor expression.
British journal of pharmacology 2005;146(2):209-16.
2005: João B Calixto
Twenty-five years of research on medicinal plants in Latin America: a personal view.
Journal of ethnopharmacology 2005;100(1-2):131-4.
2005: Candida Kassuya; Danela Leite; Lucilia Vilela de Melo; Vera Lúcia G Rehder; João B Calixto
Anti-inflammatory properties of extracts, fractions and lignans isolated from Phyllanthus amarus.
Planta medica 2005;71(8):721-6.
2005: Valfredo Schlemper; Rodrigo Medeiros; Juliano Ferreira; Maria M Campos; João B Calixto
Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro.
British journal of pharmacology 2005;145(6):740-50.
2005: Kelson A Rosa; Vinicius M Gadotti; Angelo Rosa; Ana Lúcia S Rodrigues; João B Calixto; Adair R S Santos
Evidence for the involvement of glutamatergic system in the antinociceptive effect of ascorbic acid.
Neuroscience letters 2005;381(1-2):185-8.
2005: Adair R S Santos; Vinicius M Gadotti; Gerson L Oliveira; Daiane Tibola; Ana Flavia Paszcuk; Amaro Neto; Humberto M Spindola; Márcia M Souza; Ana Lúcia S Rodrigues; João B Calixto
Mechanisms involved in the antinociception caused by agmatine in mice.
Neuropharmacology 2005;48(7):1021-34.
2005: João B Calixto; Candida Kassuya; Eunice André; Juliano Ferreira
Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions.
Pharmacology & therapeutics 2005;106(2):179-208.
2005: Michel F Otuki; Juliano Ferreira; Fabiana V Lima; Cristiane Meyre-Silva; Angela Malheiros; Luciane A Muller; Graziela S Cani; Adair R S Santos; Rosendo A Yunes; João B Calixto
Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways.
The Journal of pharmacology and experimental therapeutics 2005;313(1):310-8.
2005: Juliano Ferreira; Alessandra Beirith; Marcelo A S Mori; Ronaldo C Araújo; Michael Bader; João B Pesquero; João B Calixto
Reduced nerve injury-induced neuropathic pain in kinin B1 receptor knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(9):2405-12.
2005: Michel F Otuki; Fabiana Vieira-Lima; Angela Malheiros; Rosendo A Yunes; João B Calixto
Topical antiinflammatory effects of the ether extract from Protium kleinii and alpha-amyrin pentacyclic triterpene.
European journal of pharmacology 2005;507(1-3):253-9.
2004: João B Calixto; Rodrigo Medeiros; Elizabeth S Fernandes; Juliano Ferreira; Daniela Almeida Cabrini; Maria M Campos
Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes.
British journal of pharmacology 2004;143(7):803-18.
2004: Fernanda M da Cunha; Danielle Duma; Jamil Assreuy; Fátima C Buzzi; Rivaldo Niero; Maria M Campos; João B Calixto
Caffeic acid derivatives: in vitro and in vivo anti-inflammatory properties.
Free radical research 2004;38(11):1241-53.
2004: Andréa Dias Elpo Zomkowski; Angelo Rosa; Jaime Lin; Adair R S Santos; João B Calixto; Ana Lúcia Severo Rodrigues
Evidence for serotonin receptor subtypes involvement in agmatine antidepressant like-effect in the mouse forced swimming test.
Brain research 2004;1023(2):253-63.
2004: Rubens Rodrigues-Filho; Maria M Campos; Juliano Ferreira; Adair R S Santos; Jayme Augusto Bertelli; João B Calixto
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
Brain research 2004;1018(2):159-70.
2004: Maria M Campos; Elizabeth S Fernandes; Juliano Ferreira; Léslei B Bortolanza; Adair R S Santos; João B Calixto
Pharmacological and neurochemical evidence for antidepressant-like effects of the herbal product Catuama.
Pharmacology, biochemistry, and behavior 2004;78(4):757-64.
2004: Rodrigo Medeiros; Daniela Almeida Cabrini; Juliano Ferreira; Elizabeth S Fernandes; Marcelo A S Mori; João B Pesquero; Michael Bader; Maria Christina W Avellar; Maria M Campos; João B Calixto
Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein: a critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways.
Circulation research 2004;94(10):1375-82.
2004: Joice S Siebel; Alessandra Beirith; João B Calixto
Evidence for the involvement of metabotropic glutamatergic, neurokinin 1 receptor pathways and protein kinase C in the antinociceptive effect of dipyrone in mice.
Brain research 2004;1003(1-2):61-7.
2004: Jayme Augusto Bertelli; Adair Roberto Soares dos Santos; Madjid Taleb; João B Calixto; Jean Claude Mira; Marcos Flávio Ghizoni
Long interpositional nerve graft consistently induces incomplete motor and sensory recovery in the rat. An experimental model to test nerve repair.
Journal of neuroscience methods 2004;134(1):75-80.
2004: Eunice Andre; Juliano Ferreira; Angela Malheiros; Rosendo A Yunes; João B Calixto
Evidence for the involvement of vanilloid receptor in the antinociception produced by the dialdeydes unsaturated sesquiterpenes polygodial and drimanial in rats.
Neuropharmacology 2004;46(4):590-7.
2004: Juliano Ferreira; Gisele L da Silva; João B Calixto
Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice.
British journal of pharmacology 2004;141(5):787-94.
2004: João B Calixto; Maria M Campos; Michel F Otuki; Adair R S Santos
Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules.
Planta medica 2004;70(2):93-103.
2004: Giselle F Passos; Elizabeth S Fernandes; Maria M Campos; José G V C Araújo; Jorge L Pesquero; Glória E P Souza; Maria Christina W Avellar; Mauro Teixeira; João B Calixto
Kinin B1 receptor up-regulation after lipopolysaccharide administration: role of proinflammatory cytokines and neutrophil influx.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1839-47.
2003: Astor Grumann Júnior; Ricardo V Alves; João B Calixto
The role of calcium channels in substance P-induced contractile response in the rat iris.
Peptides 2003;24(12):1985-91.
2003: João B Calixto; Michel F Otuki; Adair R S Santos
Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB).
Planta medica 2003;69(11):973-83.
2003: Niraldo Paulino; Andreia P Dantas; Vassya Bankova; Daniela Taggliari Longhi; Amarilis Scremin; Solange L de Castro; João B Calixto
Bulgarian propolis induces analgesic and anti-inflammatory effects in mice and inhibits in vitro contraction of airway smooth muscle.
Journal of pharmacological sciences 2003;93(3):307-13.
2003: Candida Kassuya; Aline Silvestre; Vera Lúcia G Rehder; João B Calixto
Anti-allodynic and anti-oedematogenic properties of the extract and lignans from Phyllanthus amarus in models of persistent inflammatory and neuropathic pain.
European journal of pharmacology 2003;478(2-3):145-53.
2003: Angelo Rosa; Jaime Lin; João B Calixto; Adair R S Santos; Ana Lúcia S Rodrigues
Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.
Behavioural brain research 2003;144(1-2):87-93.
2003: Rubens Rodrigues-Filho; Adair R S Santos; Jayme Augusto Bertelli; João B Calixto
Avulsion injury of the rat brachial plexus triggers hyperalgesia and allodynia in the hindpaws: a new model for the study of neuropathic pain.
Brain research 2003;982(2):186-94.
2003: Mariem El Sayah; João B Calixto
New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro.
Peptides 2003;24(7):1045-51.
2003: Elizabeth S Fernandes; Giselle F Passos; Maria M Campos; José G V C Araújo; Jorge L Pesquero; Maria C Avelllar; Mauro Teixeira; João B Calixto
Mechanisms underlying the modulatory action of platelet activating factor (PAF) on the upregulation of kinin B1 receptors in the rat paw.
British journal of pharmacology 2003;139(5):973-81.
2003: Michela Mantovani; Roberto Pértile; João B Calixto; Adair R S Santos; Ana Lúcia S Rodrigues
Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway.
Neuroscience letters 2003;343(1):1-4.
2003: Danielle R Santos; João B Calixto; Glória E P Souza
Effect of a kinin B2 receptor antagonist on LPS- and cytokine-induced neutrophil migration in rats.
British journal of pharmacology 2003;139(2):271-8.
2003: Alessandra Beirith; Adair R S Santos; João B Calixto
The role of neuropeptides and capsaicin-sensitive fibres in glutamate-induced nociception and paw oedema in mice.
Brain research 2003;969(1-2):110-6.
2003: Fabiane Lunardi; Michel Guzela; Andrea T Rodrigues; Rogério Corrêa; Iriane Eger-Mangrich; Mário Steindel; Edmundo C Grisard; Jamil Assreuy; João B Calixto; Adair R S Santos
Trypanocidal and leishmanicidal properties of substitution-containing chalcones.
Antimicrobial agents and chemotherapy 2003;47(4):1449-51.
2003: M C Calixto; K M Trichês; João B Calixto
Analysis of the inflammatory response in the rat paw caused by the venom of Apis melifera bee.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52(3):132-9.
2003: Tatiana Ramos Lavich; Renato S B Cordeiro; João B Calixto; Patrícia M R e Silva; Marco A Martins
Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats.
European journal of pharmacology 2003;462(1-3):185-92.
2003: Eunice André; Angela Malheiros; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Role of nitric oxide and K+ channels in relaxation induced by polygodial in rabbit corpus cavernosum in vitro.
Journal of cardiovascular pharmacology 2003;41(2):300-6.
2003: Adair R S Santos; Ana Paula Trentin; Juliano Ferreira; Rosendo A Yunes; João B Calixto
Mechanisms involved in the antinociception caused by compound MV8612 isolated from Mandevilla velutina in mice.
Brain research 2003;961(2):269-76.
2003: Rose Mari J Vianna; Brice Ongali; Domenico Regoli; João B Calixto; Réjean Couture
Up-regulation of kinin B1 receptor in the lung of streptozotocin-diabetic rat: autoradiographic and functional evidence.
British journal of pharmacology 2003;138(1):13-22.
2003: Mariem El Sayah; João B Calixto
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
European journal of pharmacology 2003;458(1-2):175-81.
2002: R M Pinheiro; João B Calixto
Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(12):603-10.
2002: Juliano Ferreira; Maria M Campos; Ronaldo C Araújo; Michael Bader; João B Pesquero; João B Calixto
The use of kinin B1 and B2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal level.
Neuropharmacology 2002;43(7):1188-97.
2002: Léslei B Bortalanza; Juliano Ferreira; Sonia C Hess; Franco Delle Monache; Rosendo A Yunes; João B Calixto
Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice.
European journal of pharmacology 2002;453(2-3):203-8.
2002: Rivaldo Niero; Ricardo Vieira Alves; Valdir Cechinel Filho; João B Calixto; Jane E Hawkes; Antonio Euzébio Sant'Ana; Rosendo A Yunes
A new anti-oedematogenic nor-pregnane derivative isolated from Mandevilla illustris.
Planta medica 2002;68(9):850-3.
2002: C Scheidt; Adair R S Santos; Juliano Ferreira; Angela Malheiros; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Evidence for the involvement of glutamatergic receptors in the antinociception caused in mice by the sesquiterpene drimanial.
Neuropharmacology 2002;43(3):340-7.
2002: Niraldo Paulino; Fernando M Scremin; Lisiane B Raichaski; Maria Cristina Marcucci; Amarilis Scremin; João B Calixto
Mechanisms involved in the relaxant action of the ethanolic extract of propolis in the guinea-pig trachea in-vitro.
The Journal of pharmacy and pharmacology 2002;54(6):845-52.
2002: Alexandre H Campos; João B Calixto; Nestor Schor
Bradykinin induces a calcium-store- dependent calcium influx in mouse mesangial cells.
Nephron 2002;91(2):308-15.
2002: Valfredo Schlemper; João B Calixto
Mechanisms underlying the contraction induced by bradykinin in the guinea pig epithelium-denuded trachea.
Canadian journal of physiology and pharmacology 2002;80(4):360-7.
2002: A H M Cardozo; Daniela Almeida Cabrini; Maria M Campos; Giles A Rae; J P Huidobro-Toro; João B Calixto
Diabetes-induced changes in responsiveness of rat bladder and vas deferens to peptides in vitro: susceptibility to reversal by insulin.
Canadian journal of physiology and pharmacology 2002;80(4):334-40.
2002: Andrea D E Zomkowski; Luciana Hammes; Jaime Lin; João B Calixto; Adair R S Santos; Ana Lúcia S Rodrigues
Agmatine produces antidepressant-like effects in two models of depression in mice.
Neuroreport 2002;13(4):387-91.
2002: Maria M Campos; Glória E P de Souza; Natasha D Ricci; Jorge L Pesquero; Mauro Teixeira; João B Calixto
The role of migrating leukocytes in IL-1 beta-induced up-regulation of kinin B(1) receptors in rats.
British journal of pharmacology 2002;135(5):1107-14.
2002: Ana Lúcia S Rodrigues; Gisele L da Silva; Andreza S Mateussi; Elizabeth S Fernandes; Obdulio G Miguel; Rosendo A Yunes; João B Calixto; Adair R S Santos
Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus.
Life sciences 2002;70(12):1347-58.
2002: Tânia Silvia Fröde; Glória E P Souza; João B Calixto
The effects of IL-6 and IL-10 and their specific antibodies in the acute inflammatory responses induced by carrageenan in the mouse model of pleurisy.
Cytokine 2002;17(3):149-56.
2002: Alessandra Beirith; Adair R S Santos; João B Calixto
Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw.
Brain research 2002;924(2):219-28.
2002: Obdulio G Miguel; Adair R S Santos; João B Calixto; Franco Delle Monache; Rosendo A Yunes
Antinociceptive activity of the natural piperidine alkaloid hydrochlorides from Syphocampylus verticellatus.
Zeitschrift für Naturforschung. C, Journal of biosciences 2002;57(1-2):81-4.
2001: Juliano Ferreira; Maria M Campos; João B Pesquero; Ronaldo C Araújo; Michael Bader; João B Calixto
Evidence for the participation of kinins in Freund's adjuvant-induced inflammatory and nociceptive responses in kinin B1 and B2 receptor knockout mice.
Neuropharmacology 2001;41(8):1006-12.
2001: Fernanda M da Cunha; Tânia Silvia Fröde; GL Mendes; Angela Malheiros; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Additional evidence for the anti-inflammatory and anti-allergic properties of the sesquiterpene polygodial.
Life sciences 2001;70(2):159-69.
2001: R M Pinheiro; Maria M Campos; João B Calixto
Analysis of the mechanisms involved in the inflammatory response induced by des-Arg9-bradykinin in the rat pleural cavity.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2001;50(11):570-6.
2001: João B Calixto; Daniela Almeida Cabrini; Juliano Ferreira; Maria M Campos
Inflammatory pain: kinins and antagonists.
Current opinion in anaesthesiology 2001;14(5):519-26.
2001: João B Calixto; C Scheidt; Michel F Otuki; Adair R S Santos
Biological activity of plant extracts: novel analgesic drugs.
Expert opinion on emerging drugs 2001;6(2):261-79.
2001: Michel F Otuki; F V Lima; Angela Malheiros; Valdir Cechinel Filho; Franco Delle Monache; Rosendo A Yunes; João B Calixto
Evaluation of the antinociceptive action caused by ether fraction and a triterpene isolated from resin of Protium kleinii.
Life sciences 2001;69(19):2225-36.
2001: Tânia B Creczynski-Pasa; VR Bonetti; Alessandra Beirith; Karina Ckless; Marlon Konzen; Ilana Seifriz; M S Paula; César Vittorio Franco; Danilo Wilhelm-Filho; João B Calixto
Complexes trans-[RuCl(2)(nic)(4)] and trans-[RuCl(2)(i-nic)(4)] as free radical scavengers.
Journal of inorganic biochemistry 2001;86(2-3):587-94.
2001: Venício F Veiga; L Zunino; João B Calixto; Maria Lúcia Patitucci; Angelo C Pinto
Phytochemical and antioedematogenic studies of commercial copaiba oils available in Brazil.
Phytotherapy research : PTR 2001;15(6):476-80.
2001: Angela Malheiros; Valdir Cechinel Filho; C B Schmitt; C Scheidt; João B Calixto; Franco Delle Monache; Rosendo A Yunes
A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark.
Phytochemistry 2001;57(1):103-7.
2001: Maria M Campos; Daniela Almeida Cabrini; A H Cardozo; Giles A Rae; J H Toro; João B Calixto
Changes in paw oedema triggered via bradykinin B(1) and B(2) receptors in streptozotocin-diabetic rats.
European journal of pharmacology 2001;416(1-2):169-77.
2001: Rodrigo Medeiros; Daniela Almeida Cabrini; João B Calixto
The "in vivo" and "ex vivo" roles of cylcooxygenase-2, nuclear factor-kappaB and protein kinases pathways in the up-regulation of B1 receptor-mediated contraction of the rabbit aorta.
Regulatory peptides 2001;97(2-3):121-30.
2001: J F Cunha; F D Campestrini; João B Calixto; Amarilis Scremin; Niraldo Paulino
The mechanism of gentisic acid-induced relaxation of the guinea pig isolated trachea: the role of potassium channels and vasoactive intestinal peptide receptors.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2001;34(3):381-8.
2001: Tânia Silvia Fröde; Glória E P Souza; João B Calixto
The modulatory role played by TNF-alpha and IL-1 beta in the inflammatory responses induced by carrageenan in the mouse model of pleurisy.
Cytokine 2001;13(3):162-8.
2001: Daniela Almeida Cabrini; Maria M Campos; KS Tratsk; Vanessa F Merino; Jose Silva Junior; Glória E P Souza; Maria Christina W Avellar; João B Pesquero; João B Calixto
Molecular and pharmacological evidence for modulation of kinin B(1) receptor expression by endogenous glucocorticoids hormones in rats.
British journal of pharmacology 2001;132(2):567-77.
2000: E Catapan; Michel F Otuki; A M Viana; Rosendo A Yunes; Louisiane Faccio V Bresciani; Juliano Ferreira; Adair R S Santos; João B Calixto; Valdir Cechinel Filho
Pharmacological activity and chemical composition of callus culture extracts from selected species of Phyllanthus.
Die Pharmazie 2000;55(12):945-6.
2000: G D da Silva; A S Matteussi; Adair Roberto Soares dos Santos; João B Calixto; Ana Lúcia S Rodrigues
Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice.
Neuroreport 2000;11(17):3699-702.
2000: Maria M Campos; João B Calixto
Neurokinin mediation of edema and inflammation.
Neuropeptides 2000;34(5):314-22.
2000: R Luzzi; C Scheidt; JF Roos; Valdir Cechinel Filho; Adair R S Santos; João B Calixto; Rosendo A Yunes; Rivaldo Niero
Antinociceptive activity of a hydroalcoholic extract obtained from aerial parts of Sebastiania schottiana (Euphorbiaceae).
Die Pharmazie 2000;55(9):681-3.
2000: Adair R S Santos; RO de Campos; Obdulio G Miguel; Valdir Cechinel Filho; A C Siani; Rosendo A Yunes; João B Calixto
Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae).
Journal of ethnopharmacology 2000;72(1-2):229-38.
2000: João B Calixto; Alessandra Beirith; Juliano Ferreira; Adair R S Santos; Valdir Cechinel Filho; Rosendo A Yunes
Naturally occurring antinociceptive substances from plants.
Phytotherapy research : PTR 2000;14(6):401-18.
2000: T S Fröde-Saleh; João B Calixto
Synergistic antiinflammatory effect of NF-kappaB inhibitors and steroidal or non steroidal antiinflammatory drugs in the pleural inflammation induced by carrageenan in mice.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49(7):330-7.
2000: João B Calixto; Daniela Almeida Cabrini; Juliano Ferreira; Maria M Campos
Kinins in pain and inflammation.
Pain 2000;87(1):1-5.
2000: Astor Grumann Júnior; M A Dias; Ricardo V Alves; J E Boteon; João B Calixto
Mechanisms mediating substance P-induced contraction in the rat iris in vitro.
Investigative ophthalmology & visual science 2000;41(7):1861-70.
2000: P K Ferreira; Maria M Campos; João B Calixto
The role of sensorial neuropeptides in the edematogenic responses mediated by B(1) agonist des-Arg(9)-BK in rats pre-treated with LPS.
Regulatory peptides 2000;89(1-3):29-35.
2000: Mariem El Sayah; Valdir Cechinel Filho; Rosendo A Yunes; Angela Malheiros; João B Calixto
Action of polygodial on agonist-induced contractions of the rat portal vein in vitro.
Journal of cardiovascular pharmacology 2000;35(4):670-5.
2000: Tania Mazzuco; Eunice André; João B Calixto
Contribution of nitric oxide, prostanoids and Ca(2+)-activated K+ channels to the relaxant response of bradykinin in the guinea pig bronchus in vitro.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(4):383-90.
2000: Valdir Cechinel Filho; ZR Vaz; L Zunino; João B Calixto; Rosendo A Yunes
Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds.
Arzneimittel-Forschung 2000;50(3):281-5.
2000: Lucia Helena Martini; C R Souza; P B Marques; João B Calixto; Rosendo A Yunes; Diogo O Souza
Compounds extracted from Phyllantus and Jatropha elliptica inhibit the binding of [3H]glutamate and [3H]GMP-PNP in rat cerebral cortex membrane.
Neurochemical research 2000;25(2):211-5.
2000: João B Calixto
Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents).
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2000;33(2):179-89.
2000: Juliano Ferreira; A E Floriani; Valdir Cechinel Filho; Franco Delle Monache; Rosendo A Yunes; João B Calixto; Adair R S Santos
Antinociceptive properties of the methanolic extract and two triterpenes isolated from Epidendrum Mosenii stems (Orchidaceae).
Life sciences 2000;66(9):791-802.
2000: GL Mendes; Adair R S Santos; Angela Malheiros; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial.
The Journal of pharmacology and experimental therapeutics 2000;292(1):164-72.
1999: Eunice André; Angela Malheiros; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Mechanisms underlying the relaxation caused by the sesquiterpene polygodial in vessels from rabbit and guinea-pig.
European journal of pharmacology 1999;386(1):47-53.
1999: Alexandre H Campos; João B Calixto; Nestor Schor
Effects of kinins upon cytosolic calcium concentrations in mouse mesangial cells.
Immunopharmacology 1999;45(1-3):39-49.
1999: Ilana Seifriz; Marlon Konzen; Marcos M S Paula; N S Gonçalves; B Spoganickz; Tânia B Creczynski-Pasa; VR Bonetti; Alessandra Beirith; João B Calixto; César Vittorio Franco
Synthesis, potentiometric titration, electrochemical investigation and biological properties of trans-[RuCl2(dinic)4] (dinic = 3,5-pyridinecarboxylic acid).
Journal of inorganic biochemistry 1999;76(3-4):153-63.
1999: Niraldo Paulino; M G Pizollatti; R A Yunes; V C Filho; T B Creczynski-Pasa; João B Calixto
The mechanisms underlying the relaxant effect of methyl and ethyl gallates in the guinea pig trachea in vitro: contribution of potassium channels.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(3):331-6.
1999: RO de Campos; Ricardo V Alves; Juliano Ferreira; D J Kyle; Sarvajit Chakravarty; Babu J Mavunkel; João B Calixto
Oral antinociception and oedema inhibition produced by NPC 18884, a non-peptidic bradykinin B2 receptor antagonist.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(3):278-86.
1999: Adair R S Santos; RO de Campos; Obdulio G Miguel; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester.
European journal of pharmacology 1999;379(1):7-17.
1999: Ana Paula Trentin; Adair R S Santos; A Guedes; Moacir Geraldo Pizzolatti; Rosendo A Yunes; João B Calixto
Antinociception caused by the extract of Hedyosmum brasiliense and its active principle, the sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide.
Planta medica 1999;65(6):517-21.
1999: Maria M Campos; Glória E P Souza; João B Calixto
In vivo B1 kinin-receptor upregulation. Evidence for involvement of protein kinases and nuclear factor kappaB pathways.
British journal of pharmacology 1999;127(8):1851-9.
1999: Juliano Ferreira; Adair R S Santos; João B Calixto
The role of systemic, spinal and supraspinal L-arginine-nitric oxide-cGMP pathway in thermal hyperalgesia caused by intrathecal injection of glutamate in mice.
Neuropharmacology 1999;38(6):835-42.
1999: Adriana R Silva; Andréa P Larangeira; Patrícia Pacheco; João B Calixto; M G M O Henriques; Patrícia T Bozza; Hugo C Castro-Faria-Neto
Bradykinin down-regulates LPS-induced eosinophil accumulation in the pleural cavity of mice through type 2-kinin receptor activation: a role for prostaglandins.
British journal of pharmacology 1999;127(2):569-75.
1999: Sandro José Ribeiro; Raquel M Teixeira; João B Calixto; Thereza C M De Lima
Tachykinin NK(3)receptor involvement in anxiety.
Neuropeptides 1999;33(2):181-8.
1999: Mariem El Sayah; Valdir Cechinel Filho; TR Pinheiro; Rosendo A Yunes; João B Calixto
In vitro effect of the extract and the 1,7-dihydroxy-2,3-dimethoxy xanthone from Polygala cyparissias on the contractions induced by inflammatory mediators and ovalbumin in normal and actively sensitised trachea from guinea pig.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(4):218-23.
1999: Adair R S Santos; Obdulio G Miguel; Rosendo A Yunes; João B Calixto
Antinociceptive properties of the new alkaloid, cis-8, 10-di-N-propyllobelidiol hydrochloride dihydrate isolated from Siphocampylus verticillatus: evidence for the mechanism of action.
The Journal of pharmacology and experimental therapeutics 1999;289(1):417-26.
1999: Alessandra Beirith; Tânia B Creczynski-Pasa; VR Bonetti; Marlon Konzen; Ilana Seifriz; M S Paula; César Vittorio Franco; João B Calixto
Antinociceptive properties and nitric oxide synthase inhibitory action of new ruthenium complexes.
European journal of pharmacology 1999;369(3):289-97.
1999: M Gaertner; L Müller; JF Roos; Graziela S Cani; Adair R S Santos; Rivaldo Niero; João B Calixto; Rosendo A Yunes; Franco Delle Monache; Valdir Cechinel Filho
Analgesic triterpenes from Sebastiania schottiana roots.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1999;6(1):41-4.
1999: Alessandra Beirith; Adair R S Santos; João B Calixto; S C Hess; I Messana; F Ferrari; Rosendo A Yunes
Study of the antinociceptive action of the ethanolic extract and the triterpene 24-hydroxytormentic acid isolated from the stem bark of Ocotea suaveolens.
Planta medica 1999;65(1):50-5.
1999: Jayme Augusto Bertelli; M F Guizoni; Adair Roberto Soares dos Santos; João B Calixto; Hamilton Duarte
Cross-chest radial nerve transfer in brachial plexus injuries. Experimental and anatomical basis.
Chirurgie de la main 1999;18(2):122-30; discussion 131.
1999: TS Saleh; João B Calixto; Yara Santos Medeiros
Effects of anti-inflammatory drugs upon nitrate and myeloperoxidase levels in the mouse pleurisy induced by carrageenan.
Peptides 1999;20(8):949-56.
1999: Ricardo V Alves; Maria M Campos; Adair R S Santos; João B Calixto
Receptor subtypes involved in tachykinin-mediated edema formation.
Peptides 1999;20(8):921-7.
1999: Juliano Ferreira; Adair R S Santos; João B Calixto
Antinociception produced by systemic, spinal and supraspinal administration of amiloride in mice.
Life sciences 1999;65(10):1059-66.
1999: T S Fröde-Saleh; João B Calixto; Yara Santos Medeiros
Analysis of the inflammatory response induced by substance P in the mouse pleural cavity.
Peptides 1999;20(2):259-65.
1999: Tania Mazzuco; M A Dias; João B Calixto
Characterization of the mechanism involved in the relaxant response of dopexamine in the guinea pig pulmonary artery in vitro.
Journal of cardiovascular pharmacology 1999;33(1):86-92.
1998: TS Saleh; R M Vianna; Tânia B Creczynski-Pasa; Sarvajit Chakravarty; Babu J Mavunkel; D J Kyle; João B Calixto
Oral anti-inflammatory action of NPC 18884, a novel bradykinin B2 receptor antagonist.
European journal of pharmacology 1998;363(2-3):179-87.
1998: Valdir Cechinel Filho; Valfredo Schlemper; Adair R S Santos; TR Pinheiro; Rosendo A Yunes; G L Mendes; João B Calixto; Franco Delle Monache
Isolation and identification of active compounds from Drimys winteri barks.
Journal of ethnopharmacology 1998;62(3):223-7.
1998: RO de Campos; M G M O Henriques; João B Calixto
Systemic treatment with Mycobacterium bovis bacillus Calmette-Guérin (BCG) potentiates kinin B1 receptor agonist-induced nociception and oedema formation in the formalin test in mice.
Neuropeptides 1998;32(5):393-403.
1998: RO de Campos; Niraldo Paulino; C H da Silva; Amarilis Scremin; João B Calixto
Anti-hyperalgesic effect of an ethanolic extract of propolis in mice and rats.
The Journal of pharmacy and pharmacology 1998;50(10):1187-93.
1998: João B Calixto; Adair R S Santos; Valdir Cechinel Filho; Rosendo A Yunes
A review of the plants of the genus Phyllanthus: their chemistry, pharmacology, and therapeutic potential.
Medicinal research reviews 1998;18(4):225-58.
1998: Alessandra Beirith; Adair R S Santos; Ana Lúcia S Rodrigues; Tânia B Creczynski-Pasa; João B Calixto
Spinal and supraspinal antinociceptive action of dipyrone in formalin, capsaicin and glutamate tests. Study of the mechanism of action.
European journal of pharmacology 1998;345(3):233-45.
1998: Mariem El Sayah; Valdir Cechinel Filho; Rosendo A Yunes; TR Pinheiro; João B Calixto
Action of polygodial, a sesquiterpene isolated from Drymis winteri, in the guinea-pig ileum and trachea 'in vitro'.
European journal of pharmacology 1998;344(2-3):215-21.
1998: Valdir Cechinel Filho; Adair R S Santos; João B Calixto; Franco Delle Monache; Obdulio G Miguel; Rosendo A Yunes
Triterpenes from Phyllanthus sellowianus roots.
Planta medica 1998;64(2):194.
1998: Maria M Campos; Glória E P Souza; João B Calixto
Modulation of kinin B1 but not B2 receptors-mediated rat paw edema by IL-1beta and TNFalpha.
Peptides 1998;19(7):1269-76.
1998: GL Mendes; Adair R S Santos; Maria M Campos; KS Tratsk; Rosendo A Yunes; Valdir Cechinel Filho; João B Calixto
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
Life sciences 1998;63(5):369-81.
1998: L G Luciano; Pedro D'Orléans-Juste; João B Calixto; Giles A Rae
Endothelin-1 selectively potentiates the purinergic component of sympathetic neurotransmission in rat seminal vesicle.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S515-7.
1998: Valdir Cechinel Filho; Rogério Corrêa; ZR Vaz; João B Calixto; Ricardo J Nunes; TR Pinheiro; Adriano D Andricopulo; Rosendo A Yunes
Further studies on analgesic activity of cyclic imides.
Farmaco (Società chimica italiana : 1989) 1998;53(1):55-7.
1998: R M Vianna; João B Calixto
Characterization of the receptor and the mechanisms underlying the inflammatory response induced by des-Arg9-BK in mouse pleurisy.
British journal of pharmacology 1998;123(2):281-91.
1998: Jayme Augusto Bertelli; Madjid Taleb; Jean Claude Mira; Adair Roberto Soares dos Santos; João B Calixto; L Kassar
Selective restoration of sensation by peripheral nerve grafts directly implanted into the contralateral C7 dorsal root ganglion: an experimental study in rat brachial plexus.
Neurosurgery 1998;42(1):125-9.
1997: KS Tratsk; Maria M Campos; ZR Vaz; Valdir Cechinel Filho; Valfredo Schlemper; Rosendo A Yunes; João B Calixto
Anti-allergic effects and oedema inhibition caused by the extract of Drymis winteri.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46(12):509-14.
1997: Adair R S Santos; João B Calixto
Ruthenium red and capsazepine antinociceptive effect in formalin and capsaicin models of pain in mice.
Neuroscience letters 1997;235(1-2):73-6.
1997: Adair R S Santos; João B Calixto
Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice.
Neuropeptides 1997;31(4):381-9.
1997: TS Saleh; João B Calixto; Yara Santos Medeiros
Pro-inflammatory effects induced by bradykinin in a murine model of pleurisy.
European journal of pharmacology 1997;331(1):43-52.
1997: Daniela Almeida Cabrini; João B Calixto
Characterization of des-Arg9-bradykinin-induced contraction in guinea-pig gallbladder in vitro.
European journal of pharmacology 1997;331(1):31-8.
1997: Mariem El Sayah; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Action of the extract of Drymis winteri on contraction induced by inflammatory mediators, compound 48/80 and ovalbumin of the guinea-pig trachea in vitro.
General pharmacology 1997;28(5):699-704.
1997: Ana Paula Trentin; Adair R S Santos; Obdulio G Miguel; Moacir Geraldo Pizzolatti; Rosendo A Yunes; João B Calixto
Mechanisms involved in the antinociceptive effect in mice of the hydroalcoholic extract of Siphocampylus verticillatus.
The Journal of pharmacy and pharmacology 1997;49(5):567-72.
1997: Márcio M Coelho; C R Oliveira; G P Pajolla; João B Calixto; Irene Rosemir Pelá
Central involvement of kinin B1 and B2 receptors in the febrile response induced by endotoxin in rats.
British journal of pharmacology 1997;121(2):296-302.
1997: Elisabeth Wazlawik; M A Da Silva; Rodrigo Rebelo Peters; J F Correia; Mareni Rocha Farias; João B Calixto; Rosa Maria Ribeiro-do-Valle
Analysis of the role of nitric oxide in the relaxant effect of the crude extract and fractions from Eugenia uniflora in the rat thoracic aorta.
The Journal of pharmacy and pharmacology 1997;49(4):433-7.
1997: Maria M Campos; M G M O Henriques; João B Calixto
The role of B1 and B2 kinin receptors in oedema formation after long-term treatment with Mycobacterium bovis bacillus Calmette-Guérin (BCG).
British journal of pharmacology 1997;120(3):502-8.
1997: RO de Campos; Adair R S Santos; ZR Vaz; TR Pinheiro; Moacir Geraldo Pizzolatti; Valdir Cechinel Filho; Franco Delle Monache; Rosendo A Yunes; João B Calixto
Antinociceptive properties of the hydroalcoholic extract and preliminary study of a xanthone isolated from Polygala cyparissias (Polygalaceae).
Life sciences 1997;61(16):1619-30.
1996: RO de Campos; R V Alves; D J Kyle; Sarvajit Chakravarty; Babu J Mavunkel; João B Calixto
Antioedematogenic and antinociceptive actions of NPC 18521, a novel bradykinin B2 receptor antagonist.
European journal of pharmacology 1996;316(2-3):277-86.
1996: Valdir Cechinel Filho; Adair R S Santos; RO de Campos; Obdulio G Miguel; Rosendo A Yunes; F Ferrari; I Messana; João B Calixto
Chemical and pharmacological studies of Phyllanthus caroliniensis in mice.
The Journal of pharmacy and pharmacology 1996;48(12):1231-6.
1996: Niraldo Paulino; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
The relaxant effect of extract of Phyllanthus urinaria in the guinea-pig isolated trachea. Evidence for involvement of ATP-sensitive potassium channels.
The Journal of pharmacy and pharmacology 1996;48(11):1158-63.
1996: Jayme Augusto Bertelli; Adair Roberto Soares dos Santos; João B Calixto
Is axonal sprouting able to traverse the conjunctival layers of the peripheral nerve? A behavioral, motor, and sensory study of end-to-side nerve anastomosis.
Journal of reconstructive microsurgery 1996;12(8):559-63.
1996: R M Teixeira; Adair R S Santos; S J Ribeiro; João B Calixto; Giles A Rae; Thereza C M De Lima
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
European journal of pharmacology 1996;311(1):7-14.
1996: Niraldo Paulino; Valdir Cechinel Filho; Moacir Geraldo Pizzolatti; Rosendo A Yunes; João B Calixto
Mechanisms involved in the contractile responses induced by the hydroalcoholic extract of Phyllanthus urinaria on the guinea pig isolated trachea: evidence for participation of tachykinins and influx of extracellular Ca2+ sensitive to ruthenium red.
General pharmacology 1996;27(5):795-802.
1996: ZR Vaz; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Antinociceptive action of 2-(4-bromobenzoyl)-3-methyl-4,6-dimethoxy benzofuran, a novel xanthoxyline derivative on chemical and thermal models of nociception in mice.
The Journal of pharmacology and experimental therapeutics 1996;278(1):304-12.
1996: T S Saleh; João B Calixto; Yara Santos Medeiros
Anti-inflammatory effects of theophylline, cromolyn and salbutamol in a murine model of pleurisy.
British journal of pharmacology 1996;118(3):811-9.
1996: Obdulio G Miguel; João B Calixto; Adair R S Santos; I Messana; F Ferrari; Valdir Cechinel Filho; Moacir Geraldo Pizzolatti; Rosendo A Yunes
Chemical and preliminary analgesic evaluation of geraniin and furosin isolated from Phyllanthus sellowianus.
Planta medica 1996;62(2):146-9.
1996: D A Cabrini; D J Kyle; João B Calixto
A pharmacological analysis of receptor subtypes and the mechanisms mediating the biphasic response induced by kinins in the rat stomach fundus in vitro.
The Journal of pharmacology and experimental therapeutics 1996;277(1):299-307.
1996: Maria M Campos; Glória E P Souza; João B Calixto
Upregulation of B1 receptor mediating des-Arg9-BK-induced rat paw oedema by systemic treatment with bacterial endotoxin.
British journal of pharmacology 1996;117(5):793-8.
1996: C R Corrêa; D J Kyle; S Chakraverty; João B Calixto
Antinociceptive profile of the pseudopeptide B2 bradykinin receptor antagonist NPC 18688 in mice.
British journal of pharmacology 1996;117(3):552-558.
1996: Jayme Augusto Bertelli; Madjid Taleb; Jean Claude Mira; João B Calixto
Muscle fiber type reorganization and behavioral functional recovery of rat median nerve repair with vascularized or conventional nerve grafts.
Restorative neurology and neuroscience 1996;10(1):5-12.
1995: Yara Santos Medeiros; João B Calixto
Competitive and selective antagonistic action of NPC 17731 on bradykinin-induced relaxant and contractile responses of the guinea pig isolated ileum.
General pharmacology 1995;26(7):1507-11.
1995: Adair R S Santos; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus.
General pharmacology 1995;26(7):1499-1506.
1995: M A Dias; A H Campos; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea-pig urinary bladder in-vitro.
The Journal of pharmacy and pharmacology 1995;47(10):846-51.
1995: Valfredo Schlemper; João B Calixto
Mechanisms involved in the relaxant response of bradykinin in epithelium intact strips of the guinea-pig trachea.
European journal of pharmacology 1995;282(1-3):177-84.
1995: João B Calixto
Multiple mechanisms of bradykinin-induced contraction in rat and guinea pig smooth muscles in vitro.
European journal of pharmacology 1995;281(3):279-88.
1995: Obdulio G Miguel; Valdir Cechinel Filho; Moacir Geraldo Pizzolatti; Adair R S Santos; João B Calixto; F Ferrari; I Messana; Rosendo A Yunes
A triterpene and phenolic compounds from leaves and stems of Phyllanthus sellowianus.
Planta medica 1995;61(4):391.
1995: Adair R S Santos; Rivaldo Niero; Valdir Cechinel Filho; Rosendo A Yunes; Moacir Geraldo Pizzolatti; Franco Delle Monache; João B Calixto
Antinociceptive properties of steroids isolated from Phyllanthus corcovadensis in mice.
Planta medica 1995;61(4):329-32.
1995: Maria M Campos; L V Mata; João B Calixto
Expression of B1 kinin receptors mediating paw edema and formalin-induced nociception. Modulation by glucocorticoids.
Canadian journal of physiology and pharmacology 1995;73(7):812-9.
1995: Valdir Cechinel Filho; Obdulio G Miguel; Ricardo J Nunes; João B Calixto; Rosendo A Yunes
Antispasmodic activity of xanthoxyline derivatives: structure-activity relationships.
Journal of pharmaceutical sciences 1995;84(4):473-5.
1995: J Maas; Giles A Rae; J P Huidobro-Toro; João B Calixto
Characterization of kinin receptors modulating neurogenic contractions of the mouse isolated vas deferens.
British journal of pharmacology 1995;114(7):1471-7.
1995: D A Cabrini; A M Silva; João B Calixto
Mechanisms of bradykinin-induced contraction of the guinea-pig gallbladder in vitro.
British journal of pharmacology 1995;114(8):1549-56.
1995: Maria M Campos; João B Calixto
Involvement of B1 and B2 receptors in bradykinin-induced rat paw oedema.
British journal of pharmacology 1995;114(5):1005-13.
1995: Giles A Rae; João B Calixto; Pedro D'Orléans-Juste
Effects and mechanisms of action of endothelins on non-vascular smooth muscle of the respiratory, gastrointestinal and urogenital tracts.
Regulatory peptides 1995;55(1):1-46.
1995: L G Luciano; Pedro D'Orléans-Juste; João B Calixto; Giles A Rae
Endothelin-1 contracts and increases motor responses to ATP in rat seminal vesicle.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S91-4.
1994: Adair R S Santos; Valdir Cechinel Filho; Rivaldo Niero; A M Viana; F N Moreno; Maria M Campos; Rosendo A Yunes; João B Calixto
Analgesic effects of callus culture extracts from selected species of Phyllanthus in mice.
The Journal of pharmacy and pharmacology 1994;46(9):755-9.
1994: A H Campos; João B Calixto
Mechanisms involved in the contractile responses of kinins in rat portal vein rings: mediation by B1 and B2 receptors.
The Journal of pharmacology and experimental therapeutics 1994;268(2):902-9.
1994: Valfredo Schlemper; João B Calixto
Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated trachea.
British journal of pharmacology 1994;111(1):83-8.
1993: F Gorski; C R Corrêa; Valdir Cechinel Filho; Rosendo A Yunes; João B Calixto
Potent antinociceptive activity of a hydroalcoholic extract of Phyllanthus corcovadensis.
The Journal of pharmacy and pharmacology 1993;45(12):1046-9.
1993: P C Neves; M C Neves; A B Cruz; A E Sant'Ana; Rosendo A Yunes; João B Calixto
Differential effects of Mandevilla velutina compounds on paw oedema induced by phospholipase A2 and phospholipase C.
European journal of pharmacology 1993;243(3):213-9.
1993: Yara Santos Medeiros; João B Calixto
Analysis of the mechanisms underlying the biphasic responses to bradykinin in circular muscle from guinea pig ileum.
European journal of pharmacology 1993;241(2-3):157-63.
1993: C R Corrêa; João B Calixto
Evidence for participation of B1 and B2 kinin receptors in formalin-induced nociceptive response in the mouse.
British journal of pharmacology 1993;110(1):193-8.
1993: Giles A Rae; João B Calixto; Pedro D'Orléans-Juste
Big-endothelin-1 contracts rat isolated uterus via a phosphoramidon-sensitive endothelin ETA receptor-mediated mechanism.
European journal of pharmacology 1993;240(2-3):113-9.
1993: João B Calixto; I Messana; F Della Monache; F Ferrari; T Bisognin; Rosendo A Yunes
Pharmacological analysis of the methanolic extract and sorocein A, a new Diels-Alder compound isolated from the roots of Sorocea bonplandii Bailon in the isolated rat uterus and guinea pig ileum.
General pharmacology 1993;24(4):983-9.
1993: Giles A Rae; João B Calixto; Pedro D'Orléans-Juste
Conversion of big endothelin-1 in rat uterus causes contraction mediated by ETA receptors.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S192-5.
1992: João B Calixto; Rosendo A Yunes; A B Cruz; Yara Santos Medeiros
Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea.
Agents and actions 1992;36(3-4):222-9.
1992: D F Duarte; A E Sant'Ana; João B Calixto
Analysis of the vasorelaxant action of jatrophone in the isolated aorta of the rat: influence of potassium channel blockers.
European journal of pharmacology 1992;215(1):75-81.
1992: C L Guimarães; João B Calixto; Giles A Rae
Potent constrictor actions of endothelin-1, endothelin-2, and endothelin-3 in rat isolated portal vein.
Hypertension 1992;19(2 Suppl):II79-86.
1992: João B Calixto; Yara Santos Medeiros
Effect of protein kinase C and calcium on bradykinin-mediated contractions of rabbit vessels.
Hypertension 1992;19(2 Suppl):II87-93.
1992: João B Calixto; Yara Santos Medeiros
Bradykinin-induced biphasic response in the rat isolated stomach fundus: functional evidence for a novel bradykinin receptor.
Life sciences 1992;50(7):PL47-52.
1991: João B Calixto; Yara Santos Medeiros
Characterization of bradykinin mediating pertussis toxin-insensitive biphasic response in circular muscle of the isolated guinea pig ileum.
The Journal of pharmacology and experimental therapeutics 1991;259(2):659-65.
1991: João B Calixto; Rosendo A Yunes; Giles A Rae
Effect of crude extracts from Leonotis nepetaefolia (Labiatae) on rat and guinea-pig smooth muscle and rat cardiac muscle.
The Journal of pharmacy and pharmacology 1991;43(8):529-34.
1991: Yara Santos Medeiros; João B Calixto
Influence of calcium entry blockers and calmodulin inhibitors on 5-hydroxytryptamine-, potassium- and calcium-induced contractions in human umbilical artery in-vitro.
The Journal of pharmacy and pharmacology 1991;43(6):411-6.
1991: João B Calixto; J C Zanini Júnior; A B Cruz; Rosendo A Yunes; Yara Santos Medeiros
Extract and compounds obtained from Mandevilla velutina inhibit arachidonic acid-induced ear oedema in mice, but not rat stomach contraction.
Prostaglandins 1991;41(5):515-26.
1991: João B Calixto; Giles A Rae
Effects of endothelins, Bay K 8644 and other oxytocics in non-pregnant and late pregnant rat isolated uterus.
European journal of pharmacology 1991;192(1):109-16.
1991: João B Calixto; Rosendo A Yunes
Antagonism of kinin-induced contraction of isolated rat uterus by the crude hydroalcoholic extract from Mandevilla illustris.
General pharmacology 1991;22(1):99-101.
1991: João B Calixto; R L Brum; Rosendo A Yunes
Action of pregnane compounds from Mandevilla illustris against contractions induced by kinins and other oxytocics in the rat isolated uterus.
General pharmacology 1991;22(6):1071-5.
1990: Yara Santos Medeiros; João B Calixto
Inhibitory effect of diphenylhydantoin on myometrium from pregnant women in vitro. A comparative study with nicardipine and trifluoperazine.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22(5):597-603.
1990: João B Calixto; Obdulio G Miguel; Rosendo A Yunes; Giles A Rae
Action of 2-hydroxy-4,6-dimethoxyacetophenone isolated from Sebastiania schottiana.
Planta medica 1990;56(1):31-5.
1990: João B Calixto; Rosendo A Yunes
Blockade of kinin-induced responses of the guinea-pig isolated urinary bladder by the extract of Mandevilla velutina.
General pharmacology 1990;21(3):285-90.
1990: Giles A Rae; João B Calixto
Effects of endothelins on nerve-mediated contractions of the mouse vas deferens.
Life sciences 1990;47(17):PL83-9.
1990: João B Calixto; A E Sant'ana
Evidence for the mechanism of the inhibitory action of jatrophone in the isolated rat uterine muscle.
General pharmacology 1990;21(1):117-22.
1989: G H Strobel; João B Calixto; G Ballejo
Decreased gamma-aminobutyric acid (GABA) modulatory effect on rat vas deferens neurotransmission after chronic administration of imipramine.
Cellular and molecular neurobiology 1989;9(4):469-73.
1989: Gina Struffaldi Morato; João B Calixto; L Cordeiro; Thereza C M De Lima; Edelton F Morato; M Nicolau; Giles A Rae; R N Takahashi; R M Valle; Rosendo A Yunes
Chemical and pharmacological studies on Talauma ovata St. Hil. (Magnoliaceae).
Journal of ethnopharmacology 1989;26(3):277-86.
1989: H A Trebien; João B Calixto
Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom.
Agents and actions 1989;26(3-4):292-300.
1989: Giles A Rae; João B Calixto
Interactions of calcium antagonists and the calcium channel agonist Bay K 8644 on neurotransmission of the mouse isolated vas deferens.
British journal of pharmacology 1989;96(2):333-40.
1989: Yara Santos Medeiros; R C Torres; João B Calixto
Tracheal responsiveness to histamine, PAF-acether and acetylcholine in normal and actively ovalbumin-sensitized guinea pigs.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1989;22(1):97-101.
1989: Yara Santos Medeiros; João B Calixto
Effect of induced thyroid dysfunction upon uterine responsiveness in strips from pregnant and nonpregnant rats.
Pharmacology 1989;38(4):235-42.
1989: Yara Santos Medeiros; L Coelho; João B Calixto
Gossypol affects the responsiveness of isolated rat myometrium and vas deferens.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1989;22(10):1287-90.
1989: João B Calixto; A L Silva; M S Reis; R M Costa; J A Yunes; A B Cruz; Rosendo A Yunes
Demonstration of anti-bradykinin compounds in callus cultures of Mandevilla velutina.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1989;22(10):1275-9.
1989: Yara Santos Medeiros; João B Calixto
Effect of PAF-acether on the reactivity of the isolated rat myometrium.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1989;22(9):1131-5.
1989: João B Calixto
Interactions between forskolin, calcium and Bay K 8644 in K+-depolarized rat uterine muscle.
General pharmacology 1989;20(6):771-8.
1988: João B Calixto; Moacir Geraldo Pizzolatti; Rosendo A Yunes
The competitive antagonistic effect of compounds from Mandevilla velutina on kinin-induced contractions of rat uterus and guinea-pig ileum in vitro.
British journal of pharmacology 1988;94(4):1133-42.
1988: João B Calixto; M Nicolau; Rosendo A Yunes
Antagonistic effect of Mandevilla velutina extract on kinin-induced contractions of guinea-pig and cat ileum longitudinal smooth muscle.
General pharmacology 1988;19(4):595-9.
1988: João B Calixto; G H Strobel; A B Cruz; Rosendo A Yunes
Blockade of the bradykinin-evoked diphasic response of isolated rat duodenum by the crude extract of and compounds obtained from Mandevilla velutina.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1988;21(5):1015-8.
1987: João B Calixto; M Nicolau; Moacir Geraldo Pizzolatti; Rosendo A Yunes
Kinin antagonist activity of compounds from Mandevilla velutina in the rat isolated uterus.
British journal of pharmacology 1987;91(1):199-204.
1986: João B Calixto; Rosendo A Yunes; Obdulio G Miguel; Giles A Rae
Effects of Sebastiana schottiana extracts on isolated smooth muscle contraction.
Planta medica 1986;(6):444-5.
1986: João B Calixto; M Nicolau; Giles A Rae
Pharmacological actions of tannic acid. I. Effects on isolated smooth and cardiac muscles and on blood pressure.
Planta medica 1986;(1):32-5.
1985: João B Calixto; M Nicolau; Rosendo A Yunes
The selective antagonism of bradykinin action on rat isolated uterus by crude Mandevilla velutina extract.
British journal of pharmacology 1985;85(4):729-31.