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Meltzer Stephen J.

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Alexandru Olaru; Florin Selaru; Christine Vazquez; Sumitaka Yamanaka; John M Abraham; Theodore M Bayless; Yulan Cheng; Noam Harpaz; Yuriko Mori; Meltzer Stephen J.
MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease.
Arwa S Kathiria; Meltzer Stephen J.; William L Neumann; Jennifer Rhees; Rhonda F Souza; Yulan Cheng; Robert M Genta; Erin Hotchkiss; Arianne L Theiss
Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses.
Nishant Agrawal; Chetan Bettegowda; Yulan Cheng; Stefan David; Susan Hutfless; Yuchen Jiao; Kenneth W Kinzler; Nyan L Latt; Nickolas Papadopoulos; Eun Shin; William S Twaddell; Victor E Velculescu; Bert Vogelstein; Liang Wang; Li-Dong Wang; Yuxuan Wang; Wancai Yang; Meltzer Stephen J.
Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.

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2013: Alexandru Olaru; Florin Selaru; Christine Vazquez; Sumitaka Yamanaka; John M Abraham; Theodore M Bayless; Yulan Cheng; Noam Harpaz; Yuriko Mori; Meltzer Stephen J.
MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease.
Inflammatory bowel diseases 2013;19(3):471-80.
2012: Arwa S Kathiria; Meltzer Stephen J.; William L Neumann; Jennifer Rhees; Rhonda F Souza; Yulan Cheng; Robert M Genta; Erin Hotchkiss; Arianne L Theiss
Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses.
Cancer research 2012;72(22):5778-89.
2012: Nishant Agrawal; Chetan Bettegowda; Yulan Cheng; Stefan David; Susan Hutfless; Yuchen Jiao; Kenneth W Kinzler; Nyan L Latt; Nickolas Papadopoulos; Eun Shin; William S Twaddell; Victor E Velculescu; Bert Vogelstein; Liang Wang; Li-Dong Wang; Yuxuan Wang; Wancai Yang; Meltzer Stephen J.
Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.
Cancer discovery 2012;2(10):899-905.
2012: Cathy Bennett; Jacques Bergman; Pradeep Bhandari; Gianpaolo Cengia; Renzo Cestari; Amitabh Chak; Douglas A Corley; Howard Curtis; Gareth Davies; John Decaestecker; Lorna Dunn; Christian Ell; Yngve Falck-Ytter; Gary Falk; M Brian Fennerty; Mark K Ferguson; Ricky Forbes-Young; Grant Fullarton; Jean-Paul Galmiche; Robert Ganz; Laura Gay; Stuart Gittens; James J Going; John Goldblum; Charles Gordon; Heike Grabsch; Susi Green; S Michael Griffin; Chris Haigh; Rebecca Harrison; John Hart; David Hewin; Juergen Hochberger; Michio Hongo; John Inadomi; David Johnston; Peter Kahrilas; Elaine Kay; Philip Kaye; Kausilia Krishnadath; Toni Lerut; Duncan Loft; Gaius Longcroft-Wheaton; Laurence B Lovat; Lars Lundell; Philip Mairs; Peter Malfertheiner; Hendrik Manner; Meltzer Stephen J.; Paul Moayyedi; Iain Murray; Manoj Nanji; Robert Odze; Oliver Pech; Ian Penman; David Poller; Sean Preston; Krish Ragunath; Jaroslaw Regula; Thomas W Rice; Yvonne Romero; Massimo Rugge; Richard Sampliner; Scott Sanders; Nicholas J Shaheen; Prateek Sharma; Neil Shepherd; Tadakuza Shimoda; Rajvinder Singh; Stephen Sontag; Stuart Spechler; Hubert J Stein; Robert Stuart; Jan Tack; Nicholas J Talley; Tony C K Tham; Nimish Vakil; Michael Vieth; Kenneth Wang; Peter Watson; Irving Waxman; Lisa Yerian; Chris Abley; David Al Dulaimi; Haythem Ali; John Allen; Bill Allum; Mark Anderson; David Armstrong; Stephen Attwood; Hugh Barr; Janusz A Z Jankowski
Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process.
Gastroenterology 2012;143(2):336-46.
2012: Jee Hoon Song; Meltzer Stephen J.
MicroRNAs in pathogenesis, diagnosis, and treatment of gastroesophageal cancers.
Gastroenterology 2012;143(1):35-47.e2.
2012: Yulan Cheng; Stefan David; Mark D Duncan; David F Hutcheon; Soibrahim Ibrahim; Zhe Jin; Ke Ma; Meltzer Stephen J.; John M Abraham; Rachana Agarwal; Hassan Ashktorab; Alexandru Olaru; DUANE SMOOT; Jian Yang; Yuriko Mori
LARP7 is a potential tumor suppressor gene in gastric cancer.
Laboratory investigation; a journal of technical methods and pathology 2012;92(7):1013-9.
2012: Sumitaka Yamanaka; Ciprian Tomuleasa; Michael Torbenson; Rachana Agarwal; Sorin Alexandrescu; Fangmei An; Mihaela Chivu-Economescu; Simona Dima; Zhe Jin; Delgermaa Luvsanjav; Meltzer Stephen J.; Elizabeth Montgomery; Alexandru Olaru; Irinel Popescu; Florin Selaru
MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2012;44(7):589-96.
2012: Yulan Cheng; Gilbert M Green; David L Huso; RONNIE MEASE; Meltzer Stephen J.; Martin G Pomper; Srinivasan Senthamizhchelvan; George Sgouros; Rachana Agarwal; John M Abraham
[32P]ATP inhibits the growth of xenografted tumors in nude mice.
Cell cycle (Georgetown, Tex.) 2012;11(10):1878-82.
2012: Kenneth J Vega; Nathaniel Weygant; Joshua Whorton; Shrikant Anant; Stan A Lightfoot; Mohammad Madhoun; Randal May; Meltzer Stephen J.; Dongfeng Qu; Rama Ramanujam; Alessandra Reed; Rhonda Souza; Sripathi Sureban; Courtney W Houchen
Identification of the putative intestinal stem cell marker doublecortin and CaM kinase-like-1 in Barrett's esophagus and esophageal adenocarcinoma.
Journal of gastroenterology and hepatology 2012;27(4):773-80.
2012: Alexandru Olaru; Jian Yang; Wayne Yu; John M Abraham; Rachana Agarwal; Steven R Brant; Yulan Cheng; Stefan David; Noam Harpaz; David F Hutcheon; JOHN KWON; Mark Lazarev; Michael Marohn; Meltzer Stephen J.; Yuriko Mori
Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers.
Inflammatory bowel diseases 2012;18(4):641-8.
2012: Yan-Jie You; Xiao-Xuan Zheng; Meltzer Stephen J.; Yu-Ping Chen; Hao Zhang
Aberrant methylation of the PTPRO gene in peripheral blood as a potential biomarker in esophageal squamous cell carcinoma patients.
Cancer letters 2012;315(2):138-44.
2012: Rachana Agarwal; Yulan Cheng; Zhe Jin; Sahil Kumar; Yuriko Mori; Alexandru Olaru; Masato Sato; Jee Hoon Song; Amit Verma; Jian Yang; John M Abraham; Meltzer Stephen J.
Epigenomic program of Barrett's-associated neoplastic progression reveals possible involvement of insulin signaling pathways.
Endocrine-related cancer 2012;19(1):L5-9.
2012: Agustin F Fernandez; Isidre Ferrer; Mario F Fraga; Oliver Galm; Osvaldo Graña; Manuel Hidalgo; Thomas Lengauer; Ramon Martinez; Jose Ignacio Martin-Subero; Meltzer Stephen J.; David Monk; Jaume Mora; Victor Moreno; Luis Perez-Jurado; Jaime Prat; Felipe Prosper; Annibale A Puca; Susana Puig; Santiago Ropero; Marta Sanchez-Carbayo; Montse Sanchez-Cespedes; Jose V Sanchez-Mut; Reiner Siebert; Aik-Choon Tan; Hiroaki Taniguchi; Alberto Villanueva; Hiroyuki Yamamoto; Xabier Agirre; Yassen Assenov; Lina Badimon; Balazs Balint; Esteban Ballestar; Maria Berdasco; Christoph Bock; John Bridgewater; Gabriel Capella; Javier Carmona; Manel Esteller
A DNA methylation fingerprint of 1628 human samples.
Genome research 2012;22(2):407-19.
2012: Surbhi Jain; Selena Y Lin; Yih-Jyh Lin; Meltzer Stephen J.; Wei Song; Timothy M Block; Batbold Boldbaatar; Kung-Chao Chang; Ting-Tsung Chang; Sitong Chen; Shun-Hua Chen; James P Hamilton; Chi-Tan Hu; Ying-Hsiu Su
Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma.
PloS one 2012;7(4):e35789.
2011: Stefan David; Meltzer Stephen J.
MicroRNA involvement in esophageal carcinogenesis.
Current opinion in pharmacology 2011;11(6):612-6.
2011: Tetsuo Ito; Zhe Jin; Takatsugu Kan; Nobutoshi Matsumura; John M Abraham; Rachana Agarwal; Yulan Cheng; Stefan David; James P Hamilton; Yuriko Mori; Alexandru Olaru; Bogdan Paun; Fumiaki Sato; Florin Selaru; Yutaka Shimada; Kazuharu Shimizu; Jian Yang; Meltzer Stephen J.
Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer.
International journal of cancer. Journal international du cancer 2011;129(9):2134-46.
2011: Francesc Balaguer; C Richard Boland; Antoni Castells; Miriam Cuatrecasas; Meritxell Gironella; Mildred Arnold; Rodrigo Jover; Alexander Link; Xavier Llor; Juan Jose Lozano; Meltzer Stephen J.; Leticia Moreira; Georgina Ramirez; Yan Shen; Elena Stoffel; Sapna Syngal; Ajay Goel
Colorectal cancers with microsatellite instability display unique miRNA profiles.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(19):6239-49.
2011: Yuriko Mori; Alexandru Olaru; Florin Selaru; Jian Yang; Wayne Yu; Rachana Agarwal; Steven R Brant; Yulan Cheng; Mark D Duncan; Ajay Goel; David F Hutcheon; Susan Hutfless; JOHN KWON; Mark Lazarev; Delgermaa Luvsanjav; Michael Marohn; Meltzer Stephen J.
Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning.
Endocrine-related cancer 2011;18(4):465-78.
2011: Mohammed Orloff; Charissa Peterson; Todd Romigh; Jee Hoon Song; Wenjing Wu; Yi-ran Yang; Gurkan Bebek; Yulan Cheng; Stefan David; Shireen Ganapathi; Xin He; Brandie Heald; Meltzer Stephen J.; Charis Eng
Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma.
JAMA : the journal of the American Medical Association 2011;306(4):410-9.
2011: Yulan Cheng; Gilbert M Green; RONNIE MEASE; Meltzer Stephen J.; Martin G Pomper; Jian Yang; Rachana Agarwal; John M Abraham
Strong inhibition of xenografted tumor growth by low-level doses of [(32)P]ATP.
Oncotarget 2011;2(6):461-6.
2011: Fumiaki Sato; Soken Tsuchiya; Meltzer Stephen J.; Kazuharu Shimizu
MicroRNAs and epigenetics.
The FEBS journal 2011;278(10):1598-609.
2011: Zhezhen Jin; Florin Selaru; Yulan Cheng; Takatsugu Kan; Rachana Agarwal; Yuriko Mori; Alexandru Olaru; Jay Yang; Stefan David; James P Hamilton; John M Abraham; John W Harmon; Mark D Duncan; Elizabeth Montgomery; Meltzer Stephen J.
MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro.
Oncogene 2011;30(13):1577-85.
2011: Hector Alvarez; Joanna Opalinska; Li Zhou; Davendra Sohal; Melissa J Fazzari; Yiting Yu; Christina Montagna; Elizabeth Montgomery; Marcia Canto; Kerry Brandt Dunbar; JEAN WANG; Juan Carlos Roa; Yongkai Mo; Tushar Bhagat; K.H. Ramesh; Linda Cannizzaro; J Mollenhauer; Reid F Thompson; Masako Suzuki; Stephen Meltzer; Ari Melnick; John M Greally; Anirban Maitra; Meltzer Stephen J.; Amit Verma
Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.
PLoS genetics 2011;7(3):e1001356.
2011: Surbhi Jain; Pin-Wen Lin; Selena Y Lin; Yih-Jyh Lin; Meltzer Stephen J.; Florin Selaru; Wei Song; Timothy M Block; Ting-Tsung Chang; Shun-Hua Chen; Alison A Evans; James P Hamilton; Chi-Tan Hu; Ying-Hsiu Su
Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma.
PloS one 2011;6(11):e26799.
2011: Harry H Yoon; Al B Benson; Paul J Catalano; Arlene A Forastiere; Michael J Hafez; Lawrence Kleinberg; Geoffrey Liu; Meltzer Stephen J.; Elizabeth Montgomery; KATHLEEN MURPHY; Steven M Offer; Santosh Philips; Mark Powell; Todd C Skaar; Xifeng Wu; Michael K Gibson
Genetic variation in DNA-repair pathways and response to radiochemotherapy in esophageal adenocarcinoma: a retrospective cohort study of the Eastern Cooperative Oncology Group.
BMC cancer 2011;11():176.
2011: Alexandru Olaru; Florin Selaru; Yuriko Mori; Christine Vazquez; Stefan David; Bogdan Paun; Yulan Cheng; Zhe Jin; Jian Yang; Rachana Agarwal; John M Abraham; Themistocles Dassopoulos; Mary L Harris; Theodore M Bayless; JOHN KWON; Noam Harpaz; Ferenc Livak; Meltzer Stephen J.
Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation.
Inflammatory bowel diseases 2011;17(1):221-31.
2010: Manoj Kumar Kashyap; H C Harsha; Santosh Renuse; Harsh Pawar; Nandini A Sahasrabuddhe; Min-Sik Kim; Arivusudar Marimuthu; Shivakumar Keerthikumar; Babylakshmi Muthusamy; Richard Kumaran Kandasamy; Yashwanth Subbannayya; Thottethodi Subrahmanya Keshava Prasad; Riaz Mahmood; Raghothama Chaerkady; Meltzer Stephen J.; Rekha V Kumar; Anil K Rustgi; Akhilesh Pandey
SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome.
Cancer biology & therapy 2010;10(8):796-810.
2010: Feng Wu; Simin Zhang; Themistocles Dassopoulos; Mary L Harris; Theodore M Bayless; Meltzer Stephen J.; Steven R Brant; JOHN KWON
Identification of microRNAs associated with ileal and colonic Crohn's disease.
Inflammatory bowel diseases 2010;16(10):1729-38.
2010: Bogdan Paun; Debra Kukuruga; Zhe Jin; Yuriko Mori; Yulan Cheng; Mark D Duncan; Sanford A Stass; Elizabeth Montgomery; David Hutcheon; Meltzer Stephen J.
Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas.
Cancer 2010;116(19):4495-501.
2010: Stefan David; Meltzer Stephen J.
Stomach - Genetic and epigenetic alterations of preneoplastic and neoplastic lesions.
Cancer biomarkers : section A of Disease markers 2010;9(1-6):493-507.
2009: Takatsugu Kan; Meltzer Stephen J.
MicroRNAs in Barrett's esophagus and esophageal adenocarcinoma.
Current opinion in pharmacology 2009;9(6):727-32.
2009: Tadayuki Akagi; Tetsuo Ito; Motohiro Kato; Zhe Jin; Yulan Cheng; Takatsugu Kan; Go Yamamoto; Alexandru Olaru; Norihiko Kawamata; Jessica Boult; Harmik J Soukiasian; Carl W Miller; Seishi Ogawa; Meltzer Stephen J.; H Phillip Koeffler
Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.
International journal of cancer. Journal international du cancer 2009;125(10):2349-59.
2009: Yuriko Mori; Meltzer Stephen J.
Honey, I shrunk the telomere: UC speeds aging.
Inflammatory bowel diseases 2009;15(9):1432-3.
2009: Florin Selaru; Stefan David; Meltzer Stephen J.; James P Hamilton
Epigenetic events in gastrointestinal cancer.
The American journal of gastroenterology 2009;104(8):1910-2.
2009: Zhe Jin; Yulan Cheng; Wen Gu; Yingye Zheng; Fumiaki Sato; Yuriko Mori; Alexandru Olaru; Bogdan Paun; Jian Yang; Takatsugu Kan; Tetsuo Ito; James P Hamilton; Florin Selaru; Rachana Agarwal; Stefan David; John M Abraham; Herbert C Wolfsen; Michael B Wallace; Nicholas J Shaheen; Kay Washington; JEAN WANG; Marcia Canto; Achyut Bhattacharyya; Mark A Nelson; Paul D Wagner; Yvonne Romero; Kenneth K Wang; Ziding Feng; Richard E Sampliner; Meltzer Stephen J.
A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus.
Cancer research 2009;69(10):4112-5.
2009: J M Morris; H Suzuki; margaret mckernan; Meltzer Stephen J.; R C Stuart; Adrian J Stanley
Impact of EUS-FNA in the management of patients with oesophageal cancer.
Scottish medical journal 2009;54(2):30-3.
2009: Takatsugu Kan; Fumiaki Sato; Tetsuo Ito; Nobutoshi Matsumura; Stefan David; Yulan Cheng; Rachana Agarwal; Bogdan Paun; Zhe Jin; Alexandru Olaru; Florin Selaru; James P Hamilton; Jian Yang; John M Abraham; Yuriko Mori; Meltzer Stephen J.
The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim.
Gastroenterology 2009;136(5):1689-700.
2009: Florin Selaru; Alexandru Olaru; Takatsugu Kan; Stefan David; Yulan Cheng; Yuriko Mori; Jian Yang; Bogdan Paun; Zhe Jin; Rachana Agarwal; James P Hamilton; John M Abraham; Christos S Georgiades; Hector Alvarez; Perumal Vivekanandan; Wayne Yu; Anirban Maitra; Michael Torbenson; Paul J Thuluvath; Gregory J Gores; Nicholas F LaRusso; Ralph Hruban; Meltzer Stephen J.
MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.
Hepatology (Baltimore, Md.) 2009;49(5):1595-601.
2009: Rachana Agarwal; Yuriko Mori; Yulan Cheng; Zhe Jin; Alexandru Olaru; James P Hamilton; Stefan David; Florin Selaru; Jian Yang; John M Abraham; Elizabeth Montgomery; Patrice J Morin; Meltzer Stephen J.
Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells.
PloS one 2009;4(11):e8002.
2009: Bogdan Paun; Yulan Cheng; Barbara A Leggett; Joanne Young; Meltzer Stephen J.; Yuriko Mori
Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.
PloS one 2009;4(11):e7715.
2008: Zhe Jin; Yulan Cheng; Andreea Olaru; Takatsugu Kan; Jian Yang; Bogdan Paun; Tetsuo Ito; James P Hamilton; Stefan David; Rachana Agarwal; Florin Selaru; Fumiaki Sato; John M Abraham; David G Beer; Yuriko Mori; Yutaka Shimada; Meltzer Stephen J.
Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors.
International journal of cancer. Journal international du cancer 2008;123(10):2331-6.
2008: Tetsuo Ito; Yutaka Shimada; Takatsugu Kan; Stefan David; Yulan Cheng; Yuriko Mori; Rachana Agarwal; Bogdan Paun; Zhe Jin; Andreea Olaru; James P Hamilton; Jian Yang; John M Abraham; Meltzer Stephen J.; Fumiaki Sato
Pituitary tumor-transforming 1 increases cell motility and promotes lymph node metastasis in esophageal squamous cell carcinoma.
Cancer research 2008;68(9):3214-24.
2008: John M Abraham; Yulan Cheng; James P Hamilton; Bogdan Paun; Zhe Jin; Rachana Agarwal; Takatsugu Kan; Stefan David; Andreea Olaru; Jian Yang; Tetsuo Ito; Florin Selaru; Yuriko Mori; Meltzer Stephen J.
Generation of small 32P-labeled peptides as a potential approach to colorectal cancer therapy.
PloS one 2008;3(6):e2508.
2008: Fumiaki Sato; Zhe Jin; Karsten Schulmann; JEAN WANG; Bruce D Greenwald; Tetsuo Ito; Takatsugu Kan; James P Hamilton; Jian Yang; Bogdan Paun; Stefan David; Andreea Olaru; Yulan Cheng; Yuriko Mori; John M Abraham; Harris G Yfantis; Tsung-Teh Wu; Mary B Fredericksen; Kenneth K Wang; Marcia Canto; Yvonne Romero; Ziding Feng; Meltzer Stephen J.
Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features.
PloS one 2008;3(4):e1890.
2008: Zhe Jin; James P Hamilton; Jian Yang; Yuriko Mori; Andreea Olaru; Fumiaki Sato; Tetsuo Ito; Takatsugu Kan; Yulan Cheng; Bogdan Paun; Stefan David; David G Beer; Rachana Agarwal; John M Abraham; Meltzer Stephen J.
Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(1):111-7.
2008: Zhe Jin; Yuriko Mori; James P Hamilton; Andreea Olaru; Fumiaki Sato; Jian Yang; Tetsuo Ito; Takatsugu Kan; Rachana Agarwal; Meltzer Stephen J.
Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis.
Cancer 2008;112(1):43-9.
2007: Zhe Jin; Andreea Olaru; Jian Yang; Fumiaki Sato; Yulan Cheng; Takatsugu Kan; Yuriko Mori; Carmit Mantzur; Bogdan Paun; James P Hamilton; Tetsuo Ito; Suna Wang; Stefan David; Rachana Agarwal; David G Beer; John M Abraham; Meltzer Stephen J.
Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(21):6293-300.
2007: Zhe Jin; Yuriko Mori; Jian Yang; Fumiaki Sato; Tetsuo Ito; Yulan Cheng; Bogdan Paun; James P Hamilton; Takatsugu Kan; Andreea Olaru; Stefan David; Rachana Agarwal; John M Abraham; David G Beer; Elizabeth Montgomery; Meltzer Stephen J.
Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma.
Oncogene 2007;26(43):6332-40.
2007: Kazuo Konishi; Lanlan Shen; Suna Wang; Meltzer Stephen J.; Noam Harpaz; Jean-Pierre J Issa
Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias.
Gastroenterology 2007;132(4):1254-60.
2007: Tetsuo Ito; Eiji Tanaka; Tadashi Kadowaki; Takatsugu Kan; Motoshige Higashiyama; Satoshi Shiojima; Shiori Tomoda; Akira Myoumoto; Hideo Akiyama; Hitoshi Nobumasa; Shigemi Matsumoto; Shinichi Miyamoto; Michihide Mitsumori; Fumiaki Sato; Go Watanabe; Atsushi Itami; Meltzer Stephen J.; Gozoh Tsujimoto; Yutaka Shimada
An ultrasensitive new DNA microarray chip provides gene expression profiles for preoperative esophageal cancer biopsies without RNA amplification.
Oncology 2007;73(5-6):366-75.
2007: John M Abraham; Fumiaki Sato; Yulan Cheng; Bogdan Paun; Takatsugu Kan; Andreea Olaru; Zhe Jin; Jian Yang; Rachana Agarwal; Stefan David; James P Hamilton; Tetsuo Ito; Yuriko Mori; Meltzer Stephen J.
Novel decapeptides that bind avidly and deliver radioisotope to colon cancer cells.
PloS one 2007;2(10):e964.
2007: William A Kanner; Cinthia Drachenberg; John C Papadimitriou; Suna Wang; Meltzer Stephen J.; Geoffrey N Sklar
Urethral stromal tumor with pacemaker cell phenotype.
Ultrastructural pathology 2007;31(1):63-71.
2007: Zhenqiu Liu; Feng Jiang; Guoliang Tian; Suna Wang; Fumiaki Sato; Meltzer Stephen J.; Ming Tan
Sparse logistic regression with Lp penalty for biomarker identification.
Statistical applications in genetics and molecular biology 2007;6():Article6.
2006: James P Hamilton; Fumiaki Sato; Zhe Jin; Bruce D Greenwald; Tetsuo Ito; Yuriko Mori; Bogdan Paun; Takatsugu Kan; Yulan Cheng; Suna Wang; Jian Yang; John M Abraham; Meltzer Stephen J.
Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6637-42.
2006: Yuriko Mori; Kun Cai; Yulan Cheng; Suna Wang; Bogdan Paun; James P Hamilton; Zhe Jin; Fumiaki Sato; Agnes T Berki; Takatsugu Kan; Tetsuo Ito; Carmit Mantzur; John M Abraham; Meltzer Stephen J.
A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer.
Gastroenterology 2006;131(3):797-808.
2006: David Shibata; Yuriko Mori; Kun Cai; Li Zhang; Jing Yin; Abul Elahi; Richard Hamelin; Yick F Wong; Wing K Lo; Tony CHUNG; Fumiaki Sato; Martin S Karpeh; Meltzer Stephen J.
RAB32 hypermethylation and microsatellite instability in gastric and endometrial adenocarcinomas.
International journal of cancer. Journal international du cancer 2006;119(4):801-6.
2006: John P O'Neill; Chidambaram Natesa Velalar; Dong I Lee; Bin Zhang; Takeo Nakanishi; Yao Tang; Florin Selaru; Douglas Ross; Meltzer Stephen J.; Arif Hussain
Thapsigargin resistance in human prostate cancer cells.
Cancer 2006;107(3):649-59.
2006: James P Hamilton; Fumiaki Sato; Bruce D Greenwald; Mohan Suntharalingam; Mark J Krasna; Martin J Edelman; Austin Doyle; Agnes T Berki; John M Abraham; Yuriko Mori; Takatsugu Kan; Carmit Mantzur; Bogdan Paun; Suna Wang; Tetsuo Ito; Zhe Jin; Meltzer Stephen J.
Promoter methylation and response to chemotherapy and radiation in esophageal cancer.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2006;4(6):701-8.
2006: Suna Wang; M Zhan; Jing Yin; John M Abraham; Yuriko Mori; Fumiaki Sato; Yan Xu; Andreea Olaru; Agnes T Berki; Hanchen Li; Karsten Schulmann; Takatsugu Kan; James P Hamilton; Bogdan Paun; M M Yu; Zhe Jin; Yulan Cheng; Tetsuo Ito; Carmit Mantzur; Bruce D Greenwald; Meltzer Stephen J.
Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis.
Oncogene 2006;25(23):3346-56.
2006: Fumiaki Sato; John M Abraham; Jing Yin; Takatsugu Kan; Tetsuo Ito; Yuriko Mori; James P Hamilton; Zhe Jin; Yulan Cheng; Bogdan Paun; Agnes T Berki; Suna Wang; Yutaka Shimada; Meltzer Stephen J.
Polo-like kinase and survivin are esophageal tumor-specific promoters.
Biochemical and biophysical research communications 2006;342(2):465-71.
2006: James P Hamilton; Meltzer Stephen J.
A review of the genomics of gastric cancer.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2006;4(4):416-25.
2006: Takao Takahashi; Hisayuki Shigematsu; Narayan Shivapurkar; Jyotsna Reddy; Yingye Zheng; Ziding Feng; Makoto Suzuki; Masaharu Nomura; Meena Augustus; Jing Yin; Meltzer Stephen J.; Adi F Gazdar
Aberrant promoter methylation of multiple genes during multistep pathogenesis of colorectal cancers.
International journal of cancer. Journal international du cancer 2006;118(4):924-31.
2006: Fumiaki Sato; Meltzer Stephen J.
CpG island hypermethylation in progression of esophageal and gastric cancer.
Cancer 2006;106(3):483-93.
2006: Anca Sterian; Takatsugu Kan; Agnes T Berki; Yuriko Mori; Andreea Olaru; Karsten Schulmann; Fumiaki Sato; Suna Wang; Bogdan Paun; Kun Cai; James P Hamilton; John M Abraham; Meltzer Stephen J.
Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma.
Oncology 2006;70(3):168-72.
2006: Takatsugu Kan; Seiji Yamasaki; Kan Kondo; Naoki Teratani; Atsushi Kawabe; Junichi Kaganoi; Meltzer Stephen J.; Masayuki Imamura; Yutaka Shimada
A new specific gene expression in squamous cell carcinoma of the esophagus detected using representational difference analysis and cDNA microarray.
Oncology 2006;70(1):25-33.
2005: Claudia R Baquet; Patricia Commiskey; Kelly M Mack; Meltzer Stephen J.; Shiraz I Mishra
Esophageal cancer epidemiology in blacks and whites: racial and gender disparities in incidence, mortality, survival rates and histology.
Journal of the National Medical Association 2005;97(11):1471-8.
2005: Jan Brabender; Paul Marjoram; Reginald V N Lord; Ralf Metzger; Dennis Salonga; Daniel Vallböhmer; Hartmut Schäfer; Kathleen D Danenberg; Peter V Danenberg; Florin Selaru; Stephan E Baldus; Arnulf H Hölscher; Meltzer Stephen J.; Paul M Schneider
The molecular signature of normal squamous esophageal epithelium identifies the presence of a field effect and can discriminate between patients with Barrett's esophagus and patients with Barrett's-associated adenocarcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(9):2113-7.
2005: Karsten Schulmann; Yuriko Mori; Victoria Croog; Jing Yin; Andreea Olaru; Anca Sterian; Fumiaki Sato; Suna Wang; Yan Xu; Elena Deacu; Agnes T Berki; James P Hamilton; Takatsugu Kan; John M Abraham; Wolff Schmiegel; Noam Harpaz; Meltzer Stephen J.
Molecular phenotype of inflammatory bowel disease-associated neoplasms with microsatellite instability.
Gastroenterology 2005;129(1):74-85.
2005: Takao Takahashi; Makoto Suzuki; Hisayuki Shigematsu; Narayan Shivapurkar; Chinyere Echebiri; Masaharu Nomura; Victor Stastny; Meena Augustus; Cheng-Wen Wu; Ignacio I Wistuba; Meltzer Stephen J.; Adi F Gazdar
Aberrant methylation of Reprimo in human malignancies.
International journal of cancer. Journal international du cancer 2005;115(4):503-10.
2005: Karsten Schulmann; Anca Sterian; Agnes T Berki; Jing Yin; Fumiaki Sato; Yan Xu; Andreea Olaru; Suna Wang; Yuriko Mori; Elena Deacu; James P Hamilton; Takatsugu Kan; Mark J Krasna; David G Beer; Margaret S Pepe; John M Abraham; Ziding Feng; Wolff Schmiegel; Bruce D Greenwald; Meltzer Stephen J.
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk.
Oncogene 2005;24(25):4138-48.
2005: Fumiaki Sato; Yutaka Shimada; Florin Selaru; David Shibata; Masato Maeda; Go Watanabe; Yuriko Mori; Sanford A Stass; Masayuki Imamura; Meltzer Stephen J.
Prediction of survival in patients with esophageal carcinoma using artificial neural networks.
Cancer 2005;103(8):1596-605.
2005: Karsten Schulmann; Frank Brasch; Erdmute Kunstmann; Christoph Engel; Constanze Pagenstecher; Holger Vogelsang; Stefan Krüger; Tilman Vogel; Hanns-Peter Knaebel; Josef Rüschoff; Stephan Hahn; Magnus V Knebel-Doeberitz; Gabriela Moeslein; Meltzer Stephen J.; Hans K Schackert; Christiane Tympner; Elisabeth Mangold; Wolff Schmiegel
HNPCC-associated small bowel cancer: clinical and molecular characteristics.
Gastroenterology 2005;128(3):590-9.
2004: Hangxiu Xu; Rupesh Chaturvedi; Yulan Cheng; Francoise I Bussiere; Mohammad Asim; Micheal D Yao; Darryn Potosky; Meltzer Stephen J.; Juong G Rhee; Sung S Kim; Steven F Moss; Amy Hacker; Yanlin Wang; Robert A Casero; Keith T Wilson
Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis.
Cancer research 2004;64(23):8521-5.
2004: Takatsugu Kan; Yutaka Shimada; Fumiaki Sato; Tetsuo Ito; Kan Kondo; Go Watanabe; Masato Maeda; Seiji Yamasaki; Meltzer Stephen J.; Masayuki Imamura
Prediction of lymph node metastasis with use of artificial neural networks based on gene expression profiles in esophageal squamous cell carcinoma.
Annals of surgical oncology 2004;11(12):1070-8.
2004: Elena Deacu; Yuriko Mori; Fumiaki Sato; Jing Yin; Andreea Olaru; Anca Sterian; Yan Xu; Suna Wang; Karsten Schulmann; Agnes T Berki; Takatsugu Kan; John M Abraham; Meltzer Stephen J.
Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes.
Cancer research 2004;64(21):7690-6.
2004: Martha C Kimos; Suna Wang; Andrew Borkowski; Guang-Yu Yang; Chung S Yang; Kellie Perry; Andreea Olaru; Elena Deacu; Anca Sterian; John R Cottrell; John C Papadimitriou; Lopa Sisodia; Florin Selaru; Yuriko Mori; Yan Xu; Jing Yin; John M Abraham; Meltzer Stephen J.
Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression.
International journal of cancer. Journal international du cancer 2004;111(3):415-7.
2004: Neil R Stokes; Xin Zhou; Meltzer Stephen J.; James B Kaper
Transcriptional responses of intestinal epithelial cells to infection with Vibrio cholerae.
Infection and immunity 2004;72(7):4240-8.
2004: Jan Brabender; Paul Marjoram; Dennis Salonga; Ralf Metzger; Paul M Schneider; Ji Min Park; Sylke Schneider; Arnulf H Hölscher; Jing Yin; Meltzer Stephen J.; Kathleen D Danenberg; Peter V Danenberg; Reginald V N Lord
A multigene expression panel for the molecular diagnosis of Barrett's esophagus and Barrett's adenocarcinoma of the esophagus.
Oncogene 2004;23(27):4780-8.
2004: Yuriko Mori; Jing Yin; Fumiaki Sato; Anca Sterian; Lisa A Simms; Florin Selaru; Karsten Schulmann; Yan Xu; Andreea Olaru; Suna Wang; Elena Deacu; John M Abraham; Joanne Young; Barbara A Leggett; Meltzer Stephen J.
Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning.
Cancer research 2004;64(7):2434-8.
2004: Florin Selaru; Jing Yin; Andreea Olaru; Yuriko Mori; Yan Xu; Steven H Epstein; Fumiaki Sato; Elena Deacu; Suna Wang; Anca Sterian; Amy M Fulton; John M Abraham; David Shibata; Claudia R Baquet; Sanford A Stass; Meltzer Stephen J.
An unsupervised approach to identify molecular phenotypic components influencing breast cancer features.
Cancer research 2004;64(5):1584-8.
2004: Damian T McManus; Andreea Olaru; Meltzer Stephen J.
Biomarkers of esophageal adenocarcinoma and Barrett's esophagus.
Cancer research 2004;64(5):1561-9.
2004: Xinrong Ma; Qingyuan Yang; Keith T Wilson; Namita Kundu; Meltzer Stephen J.; Amy M Fulton
Promoter methylation regulates cyclooxygenase expression in breast cancer.
Breast cancer research : BCR 2004;6(4):R316-21.
2003: Andreea Olaru; Yuriko Mori; Jing Yin; Suna Wang; Martha C Kimos; Kellie Perry; Yan Xu; Fumiaki Sato; Florin Selaru; Elena Deacu; Anca Sterian; David Shibata; John M Abraham; Meltzer Stephen J.
Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors.
Laboratory investigation; a journal of technical methods and pathology 2003;83(12):1867-71.
2003: Yuriko Mori; Florin Selaru; Fumiaki Sato; Jing Yin; Lisa A Simms; Yan Xu; Andreea Olaru; Elena Deacu; Suna Wang; Jennifer M Taylor; Joanne Young; Barbara A Leggett; Jeremy R Jass; John M Abraham; David Shibata; Meltzer Stephen J.
The impact of microsatellite instability on the molecular phenotype of colorectal tumors.
Cancer research 2003;63(15):4577-82.
2003: Suna Wang; Yuriko Mori; Fumiaki Sato; Jing Yin; Yan Xu; Tongtong Zou; Andreea Olaru; Martha C Kimos; Kellie Perry; Florin Selaru; Elena Deacu; Menghong Sun; Ying-Chang Shi; David Shibata; John M Abraham; Bruce D Greenwald; Meltzer Stephen J.
An LOH and mutational investigation of the ST7 gene locus in human esophageal carcinoma.
Oncogene 2003;22(3):467-70.
2002: Keishi Yamashita; Sunil Upadhyay; Motonobu Osada; Mohammad Hoque; Yan Xiao; Masaki Mori; Fumiaki Sato; Meltzer Stephen J.; David Sidransky
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Cancer cell 2002;2(6):485-95.
2002: Fumiaki Sato; David Shibata; Noam Harpaz; Yan Xu; Jing Yin; Yuriko Mori; Suna Wang; Andreea Olaru; Elena Deacu; Florin Selaru; Martha C Kimos; Prodromos Hytiroglou; Joanne Young; Barbara A Leggett; Adi F Gazdar; Shinichi Toyooka; John M Abraham; Meltzer Stephen J.
Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma.
Cancer research 2002;62(23):6820-2.
2002: Vicki L J Whitehall; Coral V A Wynter; Michael D Walsh; Lisa A Simms; David Purdie; Nirmala Pandeya; Joanne Young; Meltzer Stephen J.; Barbara A Leggett; Jeremy R Jass
Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer.
Cancer research 2002;62(21):6011-4.
2002: Jeremy R Jass; Vicki L J Whitehall; Joanne Young; Barbara A Leggett; Meltzer Stephen J.; Nagahide Matsubara; Richard Fishel
Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002.
Cancer research 2002;62(20):5988-9; author reply 5989-90.
2002: David Shibata; Fumiaki Sato; Yuriko Mori; Kellie Perry; Jing Yin; Suna Wang; Yan Xu; Andreea Olaru; Florin Selaru; Kevin Spring; Joanne Young; John M Abraham; Meltzer Stephen J.
Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in gastric adenocarcinomas.
Cancer research 2002;62(20):5637-40.
2002: Tongtong Zou; Florin Selaru; Yan Xu; Valentina Shustova; Jing Yin; Yuriko Mori; David Shibata; Fumiaki Sato; Suma Wang; Andreea Olaru; Elena Deacu; Thomas C Liu; John M Abraham; Meltzer Stephen J.
Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon.
Oncogene 2002;21(31):4855-62.
2002: Yuriko Mori; Fumiaki Sato; Florin Selaru; Andreea Olaru; Kellie Perry; Martha C Kimos; Gen Tamura; Nagahide Matsubara; Suna Wang; Yan Xu; Jing Yin; Tongtong Zou; Barbara A Leggett; Joanne Young; Toshihiro Nukiwa; O Colin Stine; John M Abraham; David Shibata; Meltzer Stephen J.
Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers.
Cancer research 2002;62(13):3641-5.
2002: Yan Xu; Florin Selaru; Jing Yin; Tongtong Zou; Valentina Shustova; Yuriko Mori; Fumiaki Sato; Thomas C Liu; Andreea Olaru; Suna Wang; Martha C Kimos; Kellie Perry; Kena Desai; Bruce D Greenwald; Mark J Krasna; David Shibata; John M Abraham; Meltzer Stephen J.
Artificial neural networks and gene filtering distinguish between global gene expression profiles of Barrett's esophagus and esophageal cancer.
Cancer research 2002;62(12):3493-7.
2002: Shinichi Toyooka; Kiyomi O Toyooka; Kenichi Harada; Kuniharu Miyajima; Prakash Makarla; Ubaradka G Sathyanarayana; Jing Yin; Fumiaki Sato; Narayan Shivapurkar; Meltzer Stephen J.; Adi F Gazdar
Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas.
Cancer research 2002;62(12):3382-6.
2002: H Moriyama; Hiromi Sasamoto; Takeshi Kambara; Nagahide Matsubara; M Ikeda; S Baba; Meltzer Stephen J.; H T Lynch; Kenji Shimizu; Noriaki Tanaka
E2F-4 mutation in hereditary non-polyposis colorectal cancer.
Journal of experimental & clinical cancer research : CR 2002;21(2):185-9.
2002: Kara N Smolinski; John M Abraham; Rhonda F Souza; Jing Yin; Suna Wang; Yan Xu; Tongtong Zou; Dehe Kong; A Steven Fleisher; Meltzer Stephen J.
Activation of the esophagin promoter during esophageal epithelial cell differentiation.
Genomics 2002;79(6):875-80.
2002: Florin Selaru; Yan Xu; Jing Yin; Tongtong Zou; Thomas C Liu; Yuriko Mori; John M Abraham; Fumiaki Sato; Suna Wang; Charlie Twigg; Andreea Olaru; Valentina Shustova; Anatoly Leytin; Prodromos Hytiroglou; David Shibata; Noam Harpaz; Meltzer Stephen J.
Artificial neural networks distinguish among subtypes of neoplastic colorectal lesions.
Gastroenterology 2002;122(3):606-13.
2002: Fumiaki Sato; Noam Harpaz; David Shibata; Yan Xu; Jing Yin; Yuriko Mori; Tongtong Zou; Suna Wang; Kena Desai; Anatoly Leytin; Florin Selaru; John M Abraham; Meltzer Stephen J.
Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis.
Cancer research 2002;62(4):1148-51.
2002: Kiyoshi Sato; Gen Tamura; Takashi Tsuchiya; Yasushi Endoh; Ken Sakata; Teiichi Motoyama; Osamu Usuba; Wataru Kimura; Masanori Terashima; Satoshi Nishizuka; Tongtong Zou; Meltzer Stephen J.
Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer.
Virchows Archiv : an international journal of pathology 2002;440(2):160-5.
2002: Florin Selaru; Tongtong Zou; Yan Xu; Valentina Shustova; Jing Yin; Yuriko Mori; Fumiaki Sato; Suna Wang; Andreea Olaru; David Shibata; Bruce D Greenwald; Mark J Krasna; John M Abraham; Meltzer Stephen J.
Global gene expression profiling in Barrett's esophagus and esophageal cancer: a comparative analysis using cDNA microarrays.
Oncogene 2002;21(3):475-8.
2002: Valentina Shustova; Meltzer Stephen J.
Amplified RNA for gene array hybridizations.
Methods in molecular biology (Clifton, N.J.) 2002;193():227-36.
2001: Joerg Trojan; Guido Plotz; Angela Brieger; Jochen Raedle; Meltzer Stephen J.; Manfred Wolter; Stefan Zeuzem
Activation of a cryptic splice site of PTEN and loss of heterozygosity in benign skin lesions in Cowden disease.
The Journal of investigative dermatology 2001;117(6):1650-3.
2001: Mark Umansky; W Yasui; Aharon Hallak; Shlomo Brill; Itzhak Shapira; Zamir Halpern; H Hibshoosh; J Rattan; Meltzer Stephen J.; E Tahara; Nadir Arber
Proton pump inhibitors reduce cell cycle abnormalities in Barrett's esophagus.
Oncogene 2001;20(55):7987-91.
2001: Jeffrey A Toretsky; N L Zitomersky; Allen E Eskenazi; Roger W Voigt; Eric D Strauch; Chen-Chih Sun; R Huber; Meltzer Stephen J.; David Schlessinger
Glypican-3 expression in Wilms tumor and hepatoblastoma.
Journal of pediatric hematology/oncology 2001;23(8):496-9.
2001: H Takashima; Y Matsumoto; Nagahide Matsubara; Y Shirakawa; R Kawashima; Motohiko Tanino; S Ito; H Isozaki; Mamoru Ouchida; Meltzer Stephen J.; Kenji Shimizu; Noriaki Tanaka
Effect of naturally occurring E2F-4 alterations on transcriptional activation and proliferation in transfected cells.
Laboratory investigation; a journal of technical methods and pathology 2001;81(11):1565-73.
2001: Meltzer Stephen J.
Tumor genomics vs. tumor genetics: a paradigm shift?
Gastroenterology 2001;121(3):726-9.
2001: Yuriko Mori; Jing Yin; A Rashid; Barbara A Leggett; Joanne Young; Lisa A Simms; PM Kuehl; Patricia Langenberg; Meltzer Stephen J.; O Colin Stine
Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability.
Cancer research 2001;61(16):6046-9.
2001: Jan Brabender; Henning Usadel; Kathleen D Danenberg; Ralf Metzger; Paul M Schneider; Reginald V N Lord; Kumari Wickramasinghe; C E Lum; J Park; Dennis Salonga; J Singer; David Sidransky; Arnulf H Hölscher; Meltzer Stephen J.; Peter V Danenberg
Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival.
Oncogene 2001;20(27):3528-32.
2001: Manel Esteller; C Cordon-Cardo; P G Corn; Meltzer Stephen J.; K S Pohar; DAVID WATKINS; Gabriel Capella; Miguel A Peinado; X Matias-Guiu; J Prat; Stephen B Baylin; James G Herman
p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.
Cancer research 2001;61(7):2816-21.
2001: M Akhtar; Yulan Cheng; R M Magno; Hassan Ashktorab; DUANE SMOOT; Meltzer Stephen J.; Keith T Wilson
Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells.
Cancer research 2001;61(6):2399-403.
2001: A Steven Fleisher; M Esteller; Gen Tamura; A Rashid; O Colin Stine; Jing Yin; Tongtong Zou; John M Abraham; Dehe Kong; Satoshi Nishizuka; Stephen P James; Keith T Wilson; James G Herman; Meltzer Stephen J.
Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia.
Oncogene 2001;20(3):329-35.
2001: Rhonda F Souza; Meltzer Stephen J.
Microsatellite Analysis of the Insulin-Like Growth Factor II Receptor in Colorectal Carcinomas.
Methods in molecular medicine 2001;50():137-48.
2000: K Kawakami; Jan Brabender; Reginald V N Lord; Susan Groshen; Bruce D Greenwald; Mark J Krasna; Jing Yin; A Steven Fleisher; John M Abraham; David G Beer; David Sidransky; H T Huss; Tom R DeMeester; Cindy A Eads; Peter W Laird; David H Ilson; David P Kelsen; David H Harpole; M B Moore; Kathleen D Danenberg; Peter V Danenberg; Meltzer Stephen J.
Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma.
Journal of the National Cancer Institute 2000;92(22):1805-11.
2000: Robert G Hardy; Meltzer Stephen J.; Janusz A Jankowski
ABC of colorectal cancer. Molecular basis for risk factors.
BMJ (Clinical research ed.) 2000;321(7265):886-9.
2000: A Steven Fleisher; M Esteller; Noam Harpaz; Anatoly Leytin; A Rashid; Yan Xu; J Liang; O Colin Stine; Jing Yin; Tongtong Zou; John M Abraham; Dehe Kong; Keith T Wilson; Stephen P James; James G Herman; Meltzer Stephen J.
Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1.
Cancer research 2000;60(17):4864-8.
2000: Manel Esteller; A Sparks; M Toyota; Montserrat Sanchez-Cespedes; Gabriel Capella; Miguel A Peinado; S Gonzalez; Gemma Tarafa; David Sidransky; Meltzer Stephen J.; Stephen B Baylin; James G Herman
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.
Cancer research 2000;60(16):4366-71.
2000: Takashi Tsuchiya; Gen Tamura; Kiyoshi Sato; Yasushi Endoh; Ken Sakata; Zhe Jin; Teiichi Motoyama; Osamu Usuba; Wataru Kimura; Satoshi Nishizuka; Keith T Wilson; Stephen P James; Jing Yin; A Steven Fleisher; Tongtong Zou; Steven G Silverberg; Dehe Kong; Meltzer Stephen J.
Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia.
Oncogene 2000;19(32):3642-6.
2000: Gen Tamura; Jing Yin; Suna Wang; A Steven Fleisher; Tongtong Zou; John M Abraham; Dehe Kong; Kara N Smolinski; Keith T Wilson; Stephen P James; Steven G Silverberg; Satoshi Nishizuka; M Terashima; T Motoyama; Meltzer Stephen J.
E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas.
Journal of the National Cancer Institute 2000;92(7):569-73.
2000: A Steven Fleisher; Meltzer Stephen J.; Stephen P James
Colon polyps in Beckwith-Wiedmann syndrome: role of imprinted genes.
Gastroenterology 2000;118(3):637.
2000: Lisa A Simms; J Young; Carol Wicking; Meltzer Stephen J.; J R Jass; B A Leggett
The apoptotic regulatory gene, BCL10, is mutated in sporadic mismatch repair deficient colorectal cancers.
Cell death and differentiation 2000;7(2):236-7.
1999: Mark J Krasna; You Sheng Mao; Joshua R Sonett; G Tamura; Raymond T Jones; Mohan Suntharalingam; Meltzer Stephen J.
P53 gene protein overexpression predicts results of trimodality therapy in esophageal cancer patients.
The Annals of thoracic surgery 1999;68(6):2021-4; discussion 2024-5.
1999: MS Sheikh; Yanping Huang; E A Fernandez-Salas; Wafik S El-Deiry; H Friess; Sally A Amundson; Jing Yin; Meltzer Stephen J.; Nikki J Holbrook; Albert J Fornace
The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract.
Oncogene 1999;18(28):4153-9.
1999: Rhonda F Souza; S Wang; Manjusha Thakar; Kara N Smolinski; Jing Yin; Tongtong Zou; Dehe Kong; John M Abraham; Jeffrey A Toretsky; Meltzer Stephen J.
Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells.
Oncogene 1999;18(28):4063-8.
1999: Jing Yin; Noam Harpaz; Rhonda F Souza; Tongtong Zou; Dehe Kong; Suna Wang; Anatoly Leytin; N S Medalie; Kara N Smolinski; John M Abraham; A Steven Fleisher; Meltzer Stephen J.
Low prevalence of the APC I1307K sequence in Jewish and non-Jewish patients with inflammatory bowel disease.
Oncogene 1999;18(26):3902-4.
1999: Jeremy R Jass; Kelli G Biden; Margaret C Cummings; Lisa A Simms; M Walsh; EM Schoch; Meltzer Stephen J.; C Wright; J Searle; Joanne Young; Barbara A Leggett
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.
Journal of clinical pathology 1999;52(6):455-60.
1999: S Fu; Kalathur S Ramanujam; A Wong; George T Fantry; Cinthia Drachenberg; Stephen P James; Meltzer Stephen J.; Keith T Wilson
Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis.
Gastroenterology 1999;116(6):1319-29.
1999: Janusz A Jankowski; N A Wright; Meltzer Stephen J.; G Triadafilopoulos; K Geboes; Alan G Casson; D Kerr; L S Young
Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus.
The American journal of pathology 1999;154(4):965-73.
1999: A Steven Fleisher; M Esteller; Suna Wang; Gen Tamura; H Suzuki; Jing Yin; Tongtong Zou; John M Abraham; Dehe Kong; Kara N Smolinski; YQ Shi; MG Rhyu; SM Powell; Stephen P James; Keith T Wilson; James G Herman; Meltzer Stephen J.
Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability.
Cancer research 1999;59(5):1090-5.
1999: Kelli G Biden; Lisa A Simms; M Cummings; Ron Buttenshaw; EM Schoch; J Searle; G Gobe; Jeremy R Jass; Meltzer Stephen J.; Barbara A Leggett; Joanne Young
Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability.
Oncogene 1999;18(5):1245-9.
1999: J Dunn; J Garde; Kevin Dolan; John R Gosney; Robert Sutton; Meltzer Stephen J.; John Field
Multiple target sites of allelic imbalance on chromosome 17 in Barrett's oesophageal cancer.
Oncogene 1999;18(4):987-93.
1998: Elizabeth K Balcer-Kubiczek; XF Zhang; L H Han; George H Harrison; C C Davis; XJ Zhou; V Ioffe; W A McCready; John M Abraham; Meltzer Stephen J.
BIGEL analysis of gene expression in HL60 cells exposed to X rays or 60 Hz magnetic fields.
Radiation research 1998;150(6):663-72.
1998: C Richard Boland; S N Thibodeau; S R Hamilton; David Sidransky; James R Eshleman; R W Burt; Meltzer Stephen J.; M A Rodriguez-Bigas; R Fodde; G N Ranzani; sudhir srivastava
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.
Cancer research 1998;58(22):5248-57.
1998: Tongtong Zou; A Steven Fleisher; Dehe Kong; Jing Yin; Rhonda F Souza; Suna Wang; Kara N Smolinski; John M Abraham; Meltzer Stephen J.
Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
Cancer research 1998;58(21):4802-4.
1998: Lisa A Simms; Graham Radford-Smith; Kelli G Biden; Ron Buttenshaw; M Cummings; Jeremy R Jass; Joanne Young; Meltzer Stephen J.; Barbara A Leggett
Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers.
Oncogene 1998;17(15):2003-8.
1998: Kevin Dolan; J Garde; John R Gosney; M Sissons; T Wright; A N Kingsnorth; SJ Walker; Robert Sutton; Meltzer Stephen J.; John Field
Allelotype analysis of oesophageal adenocarcinoma: loss of heterozygosity occurs at multiple sites.
British journal of cancer 1998;78(7):950-7.
1998: Keith T Wilson; S Fu; Kalathur S Ramanujam; Meltzer Stephen J.
Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas.
Cancer research 1998;58(14):2929-34.
1998: H M Cawley; Meltzer Stephen J.; V M De Benedetti; Monica Hollstein; Karl-Rudolf Muehlbauer; L Liang; Patrick Williams; Rhonda F Souza; Bruce D Greenwald; John R Cottrell; A Salabes; Helmut Bartsch; Glennwood E Trivers
Anti-p53 antibodies in patients with Barrett's esophagus or esophageal carcinoma can predate cancer diagnosis.
Gastroenterology 1998;115(1):19-27.
1997: D Kong; A Suzuki; Tongtong Zou; A Sakurada; L W Kemp; S Wakatsuki; T Yokoyama; H Yamakawa; T Furukawa; M Sato; N Ohuchi; S Sato; Jing Yin; S Wang; John M Abraham; Rhonda F Souza; Kara N Smolinski; Meltzer Stephen J.; A Horii
PTEN1 is frequently mutated in primary endometrial carcinomas.
Nature genetics 1997;17(2):143-4.
1997: Rhonda F Souza; Meltzer Stephen J.
The molecular basis for carcinogenesis in metaplastic columnar-lined esophagus.
Gastroenterology clinics of North America 1997;26(3):583-97.
1997: Tongtong Zou; J Lei; YQ Shi; Jing Yin; Suna Wang; Rhonda F Souza; Dehe Kong; Y Shimada; Kara N Smolinski; Bruce D Greenwald; John M Abraham; Noam Harpaz; Meltzer Stephen J.
FHIT gene alterations in esophageal cancer and ulcerative colitis (UC).
Oncogene 1997;15(1):101-5.
1997: Suna Wang; Rhonda F Souza; Dehe Kong; Jing Yin; Kara N Smolinski; Tongtong Zou; T Frank; Joanne Young; K C Flanders; H Sugimura; John M Abraham; Meltzer Stephen J.
Deficient transforming growth factor-beta1 activation and excessive insulin-like growth factor II (IGFII) expression in IGFII receptor-mutant tumors.
Cancer research 1997;57(13):2543-6.
1997: Elizabeth K Balcer-Kubiczek; Meltzer Stephen J.; L H Han; XF Zhang; Z M Shi; George H Harrison; John M Abraham
Csa-19, a radiation-responsive human gene, identified by an unbiased two-gel cDNA library screening method in human cancer cells.
Oncogene 1997;14(25):3051-7.
1997: Rhonda F Souza; Jing Yin; Kara N Smolinski; Tongtong Zou; Suna Wang; YQ Shi; MG Rhyu; John R Cottrell; John M Abraham; Kelli G Biden; Lisa A Simms; Barbara A Leggett; G Steven Bova; T Frank; SM Powell; H Sugimura; Joanne Young; Noam Harpaz; K Shimizu; N Matsubara; Meltzer Stephen J.
Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors.
Cancer research 1997;57(12):2350-3.
1997: Lisa A Simms; Tongtong Zou; Joanne Young; YQ Shi; J Lei; R Appel; MG Rhyu; H Sugimura; G Chenevix-Trench; Rhonda F Souza; Meltzer Stephen J.; Barbara A Leggett
Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers.
Oncogene 1997;14(21):2613-8.
1997: H Ouyang; HO Shiwaku; H Hagiwara; K Miura; Tadayoshi Abe; Y Kato; H Ohtani; K Shiiba; Rhonda F Souza; Meltzer Stephen J.; Akira Horii
The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum.
Cancer research 1997;57(10):1851-4.
1997: Jing Yin; Dehe Kong; Suna Wang; Tongtong Zou; Rhonda F Souza; Kara N Smolinski; P M Lynch; S R Hamilton; H Sugimura; SM Powell; Joanne Young; John M Abraham; Meltzer Stephen J.
Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas.
Human mutation 1997;10(6):474-8.
1997: Rhonda F Souza; J Lei; Jing Yin; R Appel; Tongtong Zou; X Zhou; Suna Wang; MG Rhyu; K Cymes; O Chan; W S Park; Mark J Krasna; Bruce D Greenwald; John R Cottrell; John M Abraham; Lisa A Simms; Barbara A Leggett; Joanne Young; Noam Harpaz; Meltzer Stephen J.
A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms.
Gastroenterology 1997;112(1):40-5.
1996: J Lei; Tongtong Zou; YQ Shi; X Zhou; Kara N Smolinski; Jing Yin; Rhonda F Souza; R Appel; Suna Wang; K Cymes; O Chan; John M Abraham; Noam Harpaz; Meltzer Stephen J.
Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms.
Oncogene 1996;13(11):2459-62.
1996: Meltzer Stephen J.; S P O'Doherty; Christopher Frantz; Kara N Smolinski; Jing Yin; A B Cantor; J Liu; M Valentine; G M Brodeur; P E Berg
Allelic imbalance on chromosome 5q predicts long-term survival in neuroblastoma.
British journal of cancer 1996;74(12):1855-61.
1996: Keith T Wilson; Kalathur S Ramanujam; harry mobley; R F Musselman; Stephen P James; Meltzer Stephen J.
Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line.
Gastroenterology 1996;111(6):1524-33.
1996: Elizabeth K Balcer-Kubiczek; X F Zhang; George H Harrison; W A McCready; Z M Shi; L H Han; John M Abraham; Luther L Ampey III; Meltzer Stephen J.; M C Jacobs; C C Davis
Rodent cell transformation and immediate early gene expression following 60-Hz magnetic field exposure.
Environmental health perspectives 1996;104(11):1188-98.
1996: Rhonda F Souza; R Appel; Jing Yin; S Wang; Kara N Smolinski; John M Abraham; Tongtong Zou; YQ Shi; J Lei; John R Cottrell; K Cymes; Kelli G Biden; Lisa A Simms; Barbara A Leggett; P M Lynch; M Frazier; S M Powell; Noam Harpaz; H Sugimura; J Young; Meltzer Stephen J.
Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours.
Nature genetics 1996;14(3):255-7.
1996: Rhonda F Souza; laure garrigue-antar; J Lei; Jing Yin; R Appel; Vincent F Vellucci; Tongtong Zou; X Zhou; Suna Wang; M G Rhyu; K Cymes; O Chan; W S Park; Mark J Krasna; Bruce D Greenwald; John R Cottrell; John M Abraham; Lisa A Simms; Barbara A Leggett; Joanne Young; Noam Harpaz; Michael Reiss; Meltzer Stephen J.
Alterations of transforming growth factor-beta 1 receptor type II occur in ulcerative colitis-associated carcinomas, sporadic colorectal neoplasms, and esophageal carcinomas, but not in gastric neoplasms.
Human cell 1996;9(3):229-36.
1996: laure garrigue-antar; Rhonda F Souza; Vincent F Vellucci; Meltzer Stephen J.; Michael Reiss
Loss of transforming growth factor-beta type II receptor gene expression in primary human esophageal cancer.
Laboratory investigation; a journal of technical methods and pathology 1996;75(2):263-72.
1996: X Zhou; H Suzuki; J Lei; K Cole; Jing Yin; V Suzuki; John M Abraham; Y Shimada; M Imamura; T Chan; G J Hannon; Meltzer Stephen J.
Growth suppression of esophageal cancer cells by p16INK4 and p15INK4B in vitro.
The cancer journal from Scientific American 1996;2(4):221-4.
1996: John M Abraham; S Wang; H Suzuki; H Y Jiang; L S Rosenblum-Vos; Jing Yin; Meltzer Stephen J.
Esophagin cDNA cloning and characterization: a tissue-specific member of the small proline-rich protein family that is not expressed in esophageal tumors.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(7):855-60.
1996: Meltzer Stephen J.
The molecular biology of esophageal carcinoma.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1996;142():1-8.
1996: TK McDaniel; Meltzer Stephen J.
Direct radioactive labeling of polymerase chain reaction products.
Methods in molecular biology (Clifton, N.J.) 1996;58():325-7.
1995: P E Berg; J Liu; Jing Yin; M G Rhyu; Christopher Frantz; Meltzer Stephen J.
Microsatellite instability is infrequent in neuroblastoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1995;4(8):907-9.
1995: H Nakagawa; Lawrence R Zukerberg; K Togawa; Meltzer Stephen J.; T Nishihara; Anil K Rustgi
Human cyclin D1 oncogene and esophageal squamous cell carcinoma.
Cancer 1995;76(4):541-9.
1995: Meltzer Stephen J.
Dr. Strange DNA, or how I learned to stop cloning and love the computer.
Gastroenterology 1995;109(2):611-4.
1995: X Zhou; H Suzuki; Y Shimada; M Imamura; Jing Yin; H Y Jiang; LILA TARMIN; John M Abraham; Meltzer Stephen J.
Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines.
Genes, chromosomes & cancer 1995;13(4):285-90.
1995: Elizabeth K Balcer-Kubiczek; Jing Yin; K Lin; George H Harrison; John M Abraham; Meltzer Stephen J.
p53 mutational status and survival of human breast cancer MCF-7 cell variants after exposure to X rays or fission neutrons.
Radiation research 1995;142(3):256-62.
1995: LILA TARMIN; Jing Yin; Noam Harpaz; M Kozam; J Noordzij; L B Antonio; H Y Jiang; O Chan; K Cymes; Meltzer Stephen J.
Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms.
Cancer research 1995;55(10):2035-8.
1995: Steven Itzkowitz; Bruce D Greenwald; Meltzer Stephen J.
Colon carcinogenesis in inflammatory bowel disease.
Inflammatory bowel diseases 1995;1(2):142-58.
1994: X Zhou; LILA TARMIN; Jing Yin; H Y Jiang; H Suzuki; M G Rhyu; John M Abraham; Meltzer Stephen J.
The MTS1 gene is frequently mutated in primary human esophageal tumors.
Oncogene 1994;9(12):3737-41.
1994: S M Powell; Nickolas Papadopoulos; Kenneth W Kinzler; Kara N Smolinski; Meltzer Stephen J.
APC gene mutations in the mutation cluster region are rare in esophageal cancers.
Gastroenterology 1994;107(6):1759-63.
1994: LILA TARMIN; Jing Yin; X Zhou; H Suzuki; H Y Jiang; M G Rhyu; John M Abraham; Mark J Krasna; John R Cottrell; Meltzer Stephen J.
Frequent loss of heterozygosity on chromosome 9 in adenocarcinoma and squamous cell carcinoma of the esophagus.
Cancer research 1994;54(23):6094-6.
1994: N Harpaz; A L Peck; Jing Yin; I Fiel; M Hontanosas; Sun Wing Tommy Richard Tong; J N Laurin; John M Abraham; Bruce D Greenwald; Meltzer Stephen J.
p53 protein expression in ulcerative colitis-associated colorectal dysplasia and carcinoma.
Human pathology 1994;25(10):1069-74.
1994: H Suzuki; Noam Harpaz; LILA TARMIN; Jing Yin; H Y Jiang; J D Bell; M Hontanosas; Gabriel M Groisman; John M Abraham; Meltzer Stephen J.
Microsatellite instability in ulcerative colitis-associated colorectal dysplasias and cancers.
Cancer research 1994;54(18):4841-4.
1994: Y Huang; Jing Yin; Meltzer Stephen J.
A unique p53 intragenic deletion flanked by short direct repeats results in loss of mRNA expression in a human esophageal carcinoma.
Carcinogenesis 1994;15(8):1653-5.
1994: Meltzer Stephen J.; Jing Yin; B Manin; M G Rhyu; John R Cottrell; E Hudson; J L Redd; Mark J Krasna; John M Abraham; Brian J Reid
Microsatellite instability occurs frequently and in both diploid and aneuploid cell populations of Barrett's-associated esophageal adenocarcinomas.
Cancer research 1994;54(13):3379-82.
1994: K Togawa ; K Jaskiewicz; H Takahashi; Meltzer Stephen J.; A K Rustgi
Human papillomavirus DNA sequences in esophagus squamous cell carcinoma.
Gastroenterology 1994;107(1):128-36.
1994: M G Rhyu; W S Park; Y J Jung; Sang-Wook Choi; Meltzer Stephen J.
Allelic deletions of MCC/APC and p53 are frequent late events in human gastric carcinogenesis.
Gastroenterology 1994;106(6):1584-8.
1994: P L Blount; Patricia C Galipeau; Carissa A Sanchez; K Neshat; Douglas S Levine; Jing Yin; H Suzuki; John M Abraham; Meltzer Stephen J.; Brian J Reid
17p allelic losses in diploid cells of patients with Barrett's esophagus who develop aneuploidy.
Cancer research 1994;54(9):2292-5.
1994: J S Largey; Meltzer Stephen J.; John J Sauk; Carla Hebert; D W Archibald
Loss of heterozygosity involving the APC gene in oral squamous cell carcinomas.
Oral surgery, oral medicine, and oral pathology 1994;77(3):260-3.
1994: M G Rhyu; W S Park; Meltzer Stephen J.
Microsatellite instability occurs frequently in human gastric carcinoma.
Oncogene 1994;9(1):29-32.
1993: L S Rosenblum-Vos; Meltzer Stephen J.; J Leana-Cox; Stuart Schwartz
Cytogenetic studies of primary cultures of esophageal squamous cell carcinoma.
Cancer genetics and cytogenetics 1993;70(2):127-31.
1993: Jing Yin; Noam Harpaz; Y Tong; Y Huang; Jacqueline Laurin; Bruce D Greenwald; M Hontanosas; C Newkirk; Meltzer Stephen J.
p53 point mutations in dysplastic and cancerous ulcerative colitis lesions.
Gastroenterology 1993;104(6):1633-9.
1993: P L Blount; Meltzer Stephen J.; Jing Yin; Y Huang; Mark J Krasna; Brian J Reid
Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3221-5.
1993: Y Huang; Meltzer Stephen J.; Jing Yin; Y Tong; Esther H Chang; Shiv Srivastava; TK McDaniel; R F Boynton; Z Q Zou
Altered messenger RNA and unique mutational profiles of p53 and Rb in human esophageal carcinomas.
Cancer research 1993;53(8):1889-94.
1993: J S Largey; Meltzer Stephen J.; Jing Yin; K Norris; John J Sauk; D W Archibald
Loss of heterozygosity of p53 in oral cancers demonstrated by the polymerase chain reaction.
Cancer 1993;71(6):1933-7.
1993: Meltzer Stephen J.
Direct sequencing of polymerase chain reaction products.
Methods in molecular biology (Clifton, N.J.) 1993;15():137-41.
1993: Meltzer Stephen J.
Determination of loss of heterozygosity using polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 1993;15():129-36.
1993: TK McDaniel; Meltzer Stephen J.
Direct radioactive labeling of polymerase chain reaction products.
Methods in molecular biology (Clifton, N.J.) 1993;15():41-3.
1992: Y Huang; R F Boynton; P L Blount; R J Silverstein; Jing Yin; Y Tong; TK McDaniel; C Newkirk; James Resau; R Sridhara; B J Reid; Meltzer Stephen J.
Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancers.
Cancer research 1992;52(23):6525-30.
1992: Bruce D Greenwald; Y Huang; R Baum; Meltzer Stephen J.
Barretts carcinoma in a 25-year-old man with point mutation of the p53 tumor suppressor gene.
International journal of oncology 1992;1(3):271-5.
1992: R F Boynton; P L Blount; Jing Yin; V L Brown; Y Huang; Y Tong; TK McDaniel; C Newkirk; James Resau; W H Raskind; R C Haggitt; B J Reid; Meltzer Stephen J.
Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3385-8.
1992: D D'Amico; David P Carbone; Bruce E Johnson; Meltzer Stephen J.; John D Minna
Polymorphic sites within the MCC and APC loci reveal very frequent loss of heterozygosity in human small cell lung cancer.
Cancer research 1992;52(7):1996-9.
1992: Bruce D Greenwald; Noam Harpaz; Jing Yin; Y Huang; Y Tong; V L Brown; TK McDaniel; C Newkirk; James Resau; Meltzer Stephen J.
Loss of heterozygosity affecting the p53, Rb, and mcc/apc tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis.
Cancer research 1992;52(3):741-5.
1991: James Resau; K Sakamoto; John R Cottrell; E A Hudson; Meltzer Stephen J.
Explant organ culture: a review.
Cytotechnology 1991;7(3):137-49.
1991: R F Boynton; Y Huang; P L Blount; Brian J Reid; Wendy H Raskind; Roger C Haggitt; C Newkirk; James Resau; Jing Yin; T McDaniel; Meltzer Stephen J.
Frequent loss of heterozygosity at the retinoblastoma locus in human esophageal cancers.
Cancer research 1991;51(20):5766-9.
1991: TK McDaniel; D Carbone; T Takahashi; Peter Chumakov; Esther H Chang; Kathleen F Pirollo; Jing Yin; Y Huang; Meltzer Stephen J.
The MspI polymorphism in intron 6 of p53 (TP53) detected by digestion of PCR products.
Nucleic acids research 1991;19(17):4796.
1991: TK McDaniel; Y Huang; Jing Yin; S W Needleman; Meltzer Stephen J.
Direct radioactive labeling of unpurified PCR products using Klenow fragment.
BioTechniques 1991;11(2):164, 166.
1991: Meltzer Stephen J.; Jing Yin; Y Huang; TK McDaniel; C Newkirk; O Iseri; Bert Vogelstein; James Resau
Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4976-80.
1991: J B Schreiber; Meltzer Stephen J.; S K Kutta
Frontiers in gastroenterology: new clinical and research opportunities.
Maryland medical journal (Baltimore, Md. : 1985) 1991;40(3):205-8.
1990: Meltzer Stephen J.; S M Mane; P K Wood; James Resau; C Newkirk; J A Terzakis; B I Korelitz; W M Weinstein; S W Needleman
Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products.
Cancer research 1990;50(12):3627-30.
1990: S M Mane; Meltzer Stephen J.; J C Gutheil; V Kapil; Edward J Lee; S W Needleman
RAS gene activation in acute myelogenous leukemia: analysis by in vitro amplification and DNA base sequence determination.
Genes, chromosomes & cancer 1990;2(1):71-7.
1990: Meltzer Stephen J.; S M Mane; P K Wood; L Johnson; S W Needleman
Sequencing products of the polymerase chain reaction directly, without purification.
BioTechniques 1990;8(2):142-8.
1989: Meltzer Stephen J.; D Zhou; W M Weinstein
Tissue-specific expression of c-Ha-ras in premalignant gastrointestinal mucosae.
Experimental and molecular pathology 1989;51(3):264-74.
1989: D H Present; Meltzer Stephen J.; M P Krumholz; A Wolke; Burton I Korelitz
6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity.
Annals of internal medicine 1989;111(8):641-9.
1989: M K Mallet; S M Mane; Meltzer Stephen J.; S W Needleman
c-myc amplification coexistent with activating N-ras point mutation in the biphenotypic leukemic cell line RED-3.
Leukemia 1989;3(7):511-5.
1988: Meltzer Stephen J.; Burton I Korelitz
Pancreatitis and duodenopancreatic reflux in Crohn's disease. Case report and review of the literature.
Journal of clinical gastroenterology 1988;10(5):555-8.
1987: H Masuda; H Battifora; J Yokota; Meltzer Stephen J.; M J Cline
Specificity of proto-oncogene amplification in human malignant diseases.
Molecular biology & medicine 1987;4(4):213-27.
1987: Meltzer Stephen J.; D J Ahnen; H Battifora; J Yokota; M J Cline
Protooncogene abnormalities in colon cancers and adenomatous polyps.
Gastroenterology 1987;92(5 Pt 1):1174-80.
1987: Meltzer Stephen J.; H Z Rotterdam; B I Korelitz
Kaposi's sarcoma occurring in association with ulcerative colitis.
The American journal of gastroenterology 1987;82(4):378-81.
1986: Meltzer Stephen J.; M D Goldberg; R M Meltzer; F Claps
Appendiceal obstruction by a toothpick removed at colonoscopy.
The American journal of gastroenterology 1986;81(11):1107-8.
1986: Meltzer Stephen J.; M D Goldberg
Recurrent pancreatitis caused by vegetable matter obstruction.
The American journal of gastroenterology 1986;81(11):1091-2.
1986: C J Haber; Meltzer Stephen J.; D H Present; B I Korelitz
Nature and course of pancreatitis caused by 6-mercaptopurine in the treatment of inflammatory bowel disease.
Gastroenterology 1986;91(4):982-6.
1979: Meltzer Stephen J.
Historical profiles. Our aims. S. J. Meltzer. Presidential address.
Gastroenterology 1979;76(2):412-4.