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Chun Geun Lee

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Insa M Schmidt; Geoffrey L Chupp; Jack A Elias; Isaac E Hall; Chuan-Hua He; Sujata Kale; Chun Geun Lee; Sik Lee; Yashang Lee; Gilbert W Moeckel; chirag parikh; Lloyd G Cantley
Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function.
Won-Kyung Cho; Jack A Elias; Frank J Giordano; Robert J Homer; Yan Huang; Min-Jong Kang; Chang-Min Lee; Patty J Lee; William C Sessa; Terence K Trow; Chun Geun Lee
IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.
Yang Zhou; Jeiwook Chae; Won-Kyung Cho; Jack A Elias; Min-Jong Kang; Jonathan L Koff; Chang-Min Lee; Jae-Young Lee; Han-Oh Park; Pyeong-Oh Yoon; Chun Geun Lee
Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis.

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2013: Insa M Schmidt; Geoffrey L Chupp; Jack A Elias; Isaac E Hall; Chuan-Hua He; Sujata Kale; Chun Geun Lee; Sik Lee; Yashang Lee; Gilbert W Moeckel; chirag parikh; Lloyd G Cantley
Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function.
Journal of the American Society of Nephrology : JASN 2013;24(2):309-19.
2013: Won-Kyung Cho; Jack A Elias; Frank J Giordano; Robert J Homer; Yan Huang; Min-Jong Kang; Chang-Min Lee; Patty J Lee; William C Sessa; Terence K Trow; Chun Geun Lee
IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2013;304(2):L112-24.
2012: Yang Zhou; Jeiwook Chae; Won-Kyung Cho; Jack A Elias; Min-Jong Kang; Jonathan L Koff; Chang-Min Lee; Jae-Young Lee; Han-Oh Park; Pyeong-Oh Yoon; Chun Geun Lee
Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis.
The Journal of biological chemistry 2012;287(50):41991-2000.
2012: Chun Geun Lee; Chang-Min Lee; Xueyan Peng; John Varga; Yang Zhou; Carol Feghali-Bostwick; Mridu Gulati; Erica L Herzog; Sergio A Jimenez; Farida Ahangari; Jack A Elias
Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-β1 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(5):2635-44.
2012: Charles Dela Cruz; Richard Flavell; Alex Gornitzky; Chuan Hua He; Adam Jacoby; Chun Geun Lee; Wei Liu; Bing Ma; Jack A Elias
Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses.
Cell host & microbe 2012;12(1):34-46.
2012: Min-Jong Kang; Bo Hye Kim; Do-Hyun Kim; Chun Geun Lee; Chang-Min Lee; Won-Kyung Cho; Gina Choe; Je-Min Choi; Jack A Elias
IL-18 induces emphysema and airway and vascular remodeling via IFN-γ, IL-17A, and IL-13.
American journal of respiratory and critical care medicine 2012;185(11):1205-17.
2012: Chun Geun Lee; Bing Ma; Mario Sznol; Yang Zhou; Farida Ahangari; Charles Dela Cruz; Ruth Halaban; Jack A Elias
Chitinase-like proteins in lung injury, repair, and metastasis.
Proceedings of the American Thoracic Society 2012;9(2):57-61.
2012: Chun Geun Lee; Stephen M Rosenberg; Farida Ahangari; Charles Dela Cruz; Erica Herzog; Jack A Elias
YKL-40, a chitinase-like protein at the intersection of inflammation and remodeling.
American journal of respiratory and critical care medicine 2012;185(7):692-4.
2012: Chang-Min Lee; Jun Sik Lee; Kyung Tae Noh; Jun Ho Park; Jin Wook Park; Sung-Joo Park; Yong Kyoo Shin; Jeong Hyun Chang; Won-Kyung Cho; Il-Whan Choi; Myung-Kwan Han; Deok Rim Heo; In Duk Jung; Jong-Suk Kim; Chun Geun Lee; Yeong-Min Park
An essential regulatory role of downstream of kinase-1 in the ovalbumin-induced murine model of asthma.
PloS one 2012;7(4):e34554.
2011: Chun Geun Lee; Bing Ma; Seyedtaghi Takyar; Farida Ahangari; Charles Delacruz; Chuan Hua He; Jack A Elias
Studies of vascular endothelial growth factor in asthma and chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society 2011;8(6):512-5.
2011: Hiroshi Matsuura; Yang Zhou; Charles Dela Cruz; Won Kyoo Cho; Geoffrey L Chupp; Jack A Elias; Dominik Hartl; Robert J Homer; Min-Jong Kang; Barbara Koller; Chun Geun Lee
Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema.
American journal of respiratory cell and molecular biology 2011;44(6):777-86.
2011: Bing Ma; Charles Dela Cruz; Dominik Hartl; Min-Jong Kang; Shervin Takyar; Robert J Homer; Chun Geun Lee; Jack A Elias
RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism.
American journal of respiratory and critical care medicine 2011;183(10):1322-35.
2011: Byung-Jae Lee; Hyung-Geun Moon; Tae-Seop Shin; Seong Gyu Jeon; Eun-Young Lee; Yong Song Gho; Chun Geun Lee; Zhou Zhu; Jack A Elias; Yoon-Keun Kim
Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-γ.
Experimental & molecular medicine 2011;43(4):169-78.
2011: Jack A Elias; Chun Geun Lee
IL-13 in asthma. The successful integration of lessons from mice and humans.
American journal of respiratory and critical care medicine 2011;183(8):957-8.
2011: Charles Dela Cruz; Min-Jong Kang; Won-Kyung Cho; Chun Geun Lee
Transgenic modelling of cytokine polarization in the lung.
Immunology 2011;132(1):9-17.
2011: Chun Geun Lee; Carla A Da Silva; Charles Dela Cruz; Farida Ahangari; Bing Ma; Min-Jong Kang; Chuan-Hua He; Seyedtaghi Takyar; Jack A Elias
Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury.
Annual review of physiology 2011;73():479-501.
2010: Carla A Da Silva; Pierre Pochard; Chun Geun Lee; Jack A Elias
Chitin particles are multifaceted immune adjuvants.
American journal of respiratory and critical care medicine 2010;182(12):1482-91.
2010: Je-Min Choi; Jae-Hun Shin; Myung-Hyun Sohn; Martha J Harding; Jong-Hyun Park; Zuzana Tobiasova; Da-Young Kim; Stephen E Maher; Wook-Jin Chae; Sung-Ho Park; Chun Geun Lee; Sang-Kyou Lee; Alfred L M Bothwell
Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(43):18575-80.
2010: Myung Hyun Sohn; Min-Jong Kang; Hiroshi Matsuura; Vineet Bhandari; ningyuan chen; Chun Geun Lee; Jack A Elias
The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury.
American journal of respiratory and critical care medicine 2010;182(7):918-28.
2010: You-Sun Kim; Seng-Jin Choi; Jun-Pyo Choi; Seong Gyu Jeon; Sun-Young Oh; Byung-Jae Lee; Yong Song Gho; Chun Geun Lee; Zhou Zhu; Jack A Elias; Yoon-Keun Kim
IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model.
Experimental & molecular medicine 2010;42(8):533-46.
2010: Byung Hee Koh; Soo Seok Hwang; Joo Young Kim; Wonyong Lee; Min-Jong Kang; Chun Geun Lee; Jung-Won Park; Richard A Flavell; Gap Ryol Lee
Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(23):10614-9.
2010: Chun Geun Lee; Jack A Elias
Role of breast regression protein-39/YKL-40 in asthma and allergic responses.
Allergy, asthma & immunology research 2010;2(1):20-7.
2009: Eun-Gyoung Hong; Hwi Jin Ko; You-Ree Cho; Hyo-Jeong Kim; Zhexi Ma; Tim Y Yu; Randall H Friedline; Evelyn Kurt-Jones; Robert Finberg; Matthew A Fischer; Erica L Granger; Christopher C Norbury; Stephen D Hauschka; William M Philbrick; Chun Geun Lee; Jack A Elias; Jason K Kim
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.
Diabetes 2009;58(11):2525-35.
2009: Svetlana Chapoval; Chun Geun Lee; Chuyan Tang; Achsah D Keegan; Lauren Cohn; Kim Bottomly; Jack A Elias
Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation.
Clinical immunology (Orlando, Fla.) 2009;132(3):371-84.
2009: Chun Geun Lee; Dominik Hartl; Gap Ryol Lee; Barbara Koller; Hiroshi Matsuura; Carla A Da Silva; Myung Hyun Sohn; Lauren Cohn; Robert J Homer; Alexander A Kozhich; Alison A Humbles; Jennifer Kearley; Anthony J Coyle; Geoffrey L Chupp; Jennifer L Reed; Richard A Flavell; Jack A Elias
Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis.
The Journal of experimental medicine 2009;206(5):1149-66.
2009: Dominik Hartl; Chuan Hua He; Babara Koller; Carla A Da Silva; Yasushi Kobayashi; Chun Geun Lee; Richard A Flavell; Jack A Elias
Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):5098-106.
2009: Myung Hyun Sohn; Ji Hyun Lee; Kyung Won Kim; So Won Kim; Sung Hee Lee; Kyu-Earn Kim; Kyung Hwan Kim; Chun Geun Lee; Jack A Elias; Min Goo Lee
Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy.
American journal of respiratory and critical care medicine 2009;179(6):449-56.
2009: Chun Geun Lee
Chitin, chitinases and chitinase-like proteins in allergic inflammation and tissue remodeling.
Yonsei medical journal 2009;50(1):22-30.
2008: Chun Geun Lee; Carla A Da Silva; Jae-Young Lee; Dominik Hartl; Jack A Elias
Chitin regulation of immune responses: an old molecule with new roles.
Current opinion in immunology 2008;20(6):684-9.
2008: Chun Geun Lee; Dominik Hartl; Hiroshi Matsuura; Felicity M Dunlop; Pierre D Scotney; Louis J Fabri; Andrew D Nash; ningyuan chen; Chu-Yan Tang; Qingsheng Chen; Robert J Homer; Manuel Baca; Jack A Elias
Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production.
American journal of respiratory cell and molecular biology 2008;39(6):739-46.
2008: J-I Youn; Su-Hyung Park; Hyun-Tak Jin; Chun Geun Lee; S-H Seo; M-Y Song; C-W Lee; Young Chul Sung
Enhanced delivery efficiency of recombinant adenovirus into tumor and mesenchymal stem cells by a novel PTD.
Cancer gene therapy 2008;15(11):703-12.
2008: Vineet Bhandari; Rayman Choo-Wing; Chun Geun Lee; Kamran Yusuf; Jonathan H Nedrelow; Namasivayam Ambalavanan; Herbert Malkus; Robert J Homer; Jack A Elias
Developmental regulation of NO-mediated VEGF-induced effects in the lung.
American journal of respiratory cell and molecular biology 2008;39(4):420-30.
2008: Min Jong Kang; Chun Geun Lee; Jae-Young Lee; Charles Dela Cruz; Zhijian J Chen; Richard I Enelow; Jack A Elias
Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.
The Journal of clinical investigation 2008;118(8):2771-84.
2008: Masashi Yamasaki; Hye-Ryun Kang; Robert J Homer; Svetlana Chapoval; Soo Jung Cho; Byung Jae Lee; Jack A Elias; Chun Geun Lee
P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway.
American journal of respiratory cell and molecular biology 2008;38(3):346-53.
2007: Geoffrey L Chupp; Chun Geun Lee; Nizar N Jarjour; Yun Michael Shim; Carole T Holm; Susan He; James Dziura; Jennifer L Reed; Anthony J Coyle; Peter Kiener; Mark Cullen; Martine Grandsaigne; Marie-Christine Dombret; Michel Aubier; Marina Pretolani; Jack A Elias
A chitinase-like protein in the lung and circulation of patients with severe asthma.
The New England journal of medicine 2007;357(20):2016-27.
2007: Jung Mi Kim; Oh Young Lee; Chun Geun Lee; Sung Joon Kwon; Kyung Suk Kim; Won Moon; Dong Hee Koh; Hang Lak Lee; Byung Chul Yoon; Ho Soon Choi; Joon Soo Hahm; Min Ho Lee; Dong Hoo Lee
[p53 Codon 72 and 16-bp duplication polymorphisms of gastric cancer in Koreans].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2007;50(5):292-8.
2007: Hye-Ryun Kang; Chun Geun Lee; Robert J Homer; Jack A Elias
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis.
The Journal of experimental medicine 2007;204(5):1083-93.
2007: Jonathan M Siner; Ge Jiang; Zaza I Cohen; Peiying Shan; Xuchen Zhang; Chun Geun Lee; Jack A Elias; Patty J Lee
VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(7):1422-32.
2007: Seong Gyu Jeon; Chun Geun Lee; MIN-HEE OH; Eun-Young Chun; Yong Song Gho; Sang-Heon Cho; Jong-Hoon Kim; Kyung-Up Min; You-Young Kim; Yoon-Keun Kim; Jack A Elias
Recombinant basic fibroblast growth factor inhibits the airway hyperresponsiveness, mucus production, and lung inflammation induced by an allergen challenge.
The Journal of allergy and clinical immunology 2007;119(4):831-7.
2007: Hye-Ryun Kang; Soo Jung Cho; Chun Geun Lee; Robert J Homer; Jack A Elias
Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.
The Journal of biological chemistry 2007;282(10):7723-32.
2007: Min Jong Kang; Robert J Homer; Amy Gallo; Chun Geun Lee; Kristina Crothers; Soo Jung Cho; Carolyn L Rochester; Hilary Cain; Geoffrey L Chupp; Ho Joo Yoon; Jack A Elias
IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1948-59.
2006: Vineet Bhandari; Rayman Choo-Wing; Chun Geun Lee; Zhou Zhu; Jonathan H Nedrelow; Geoffrey L Chupp; Xucher Zhang; Michael A Matthay; Lorraine B Ware; Robert J Homer; Patty J Lee; Anke Geick; Antonin R de Fougerolles; Jack A Elias
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.
Nature medicine 2006;12(11):1286-93.
2006: Min Jong Kang; Chun Geun Lee; Soo Jung Cho; Robert J Homer; Jack A Elias
IFN-gamma-dependent DNA injury and/or apoptosis are critical in cigarette smoke-induced murine emphysema.
Proceedings of the American Thoracic Society 2006;3(6):517-8.
2006: Jack A Elias; Min Jong Kang; Kristina Crothers; Kristina Crouthers; Robert J Homer; Chun Geun Lee
State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice.
Proceedings of the American Thoracic Society 2006;3(6):494-8.
2006: Chun Geun Lee; Soojung Cho; Robert J Homer; Jack A Elias
Genetic control of transforming growth factor-beta1-induced emphysema and fibrosis in the murine lung.
Proceedings of the American Thoracic Society 2006;3(6):476-477.
2006: Vineet Bhandari; Rayman Choo-Wing; Svetlana Chapoval; Chun Geun Lee; C Tang; Yoon-Keun Kim; Bing Ma; Peter Baluk; Michelle I Lin; Donald M McDonald; Robert J Homer; William C Sessa; Jack A Elias
Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(29):11021-6.
2006: Chun Geun Lee; Hye-Ryun Kang; Robert J Homer; Geoffrey L Chupp; Jack A Elias
Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling.
Proceedings of the American Thoracic Society 2006;3(5):418-23.
2006: Bing Ma; Michael R Blackburn; Chun Geun Lee; Robert J Homer; Wei Liu; Richard A Flavell; Lynn Boyden; Richard P Lifton; Chun-Xiao Sun; Hays W J Young; Jack A Elias
Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis.
The Journal of clinical investigation 2006;116(5):1274-83.
2006: Bing Ma; Wei Liu; Robert J Homer; Patty J Lee; Anthony J Coyle; Jose M Lora; Chun Geun Lee; Jack A Elias
Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4968-78.
2006: Soo Jung Cho; Min Jong Kang; Robert J Homer; Hye-Ryun Kang; Xuchen Zhang; Patty J Lee; Jack A Elias; Chun Geun Lee
Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.
The Journal of biological chemistry 2006;281(12):8161-8.
2006: Janci L Chunn; Amir Mohsenin; Hays W J Young; Chun Geun Lee; Jack A Elias; Rodney E Kellems; Janci Chunn Lindsay
Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations.
American journal of physiology. Lung cellular and molecular physiology 2006;290(3):L579-87.
2006: Patty J Lee; Xuchen Zhang; Peiying Shan; Bing Ma; Chun Geun Lee; Robert J Homer; Zhou Zhu; Mercedes Rincon; Brooke T Mossman; Jack A Elias
ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
The Journal of clinical investigation 2006;116(1):163-73.
2005: Bing Ma; Min Jong Kang; Chun Geun Lee; Svetlana Chapoval; Wei Liu; Qingsheng Chen; Anthony J Coyle; Jose M Lora; Dominic Picarella; Robert J Homer; Jack A Elias
Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema.
The Journal of clinical investigation 2005;115(12):3460-72.
2005: Jack A Elias; Robert J Homer; Qutayba Hamid; Chun Geun Lee
Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma.
The Journal of allergy and clinical immunology 2005;116(3):497-500.
2005: Patrice M Becker; Johannes Waltenberger; Robin Yachechko; Tamara Mirzapoiazova; James Sham; Chun Geun Lee; Jack A Elias; Alexander Dmitriyevich Verin
Neuropilin-1 regulates vascular endothelial growth factor-mediated endothelial permeability.
Circulation research 2005;96(12):1257-65.
2005: Tao Zheng; Min Jong Kang; Kristina Crothers; Zhou Zhu; Wei Liu; Chun Geun Lee; Lesley A Rabach; Harold A Chapman; Robert J Homer; David Aldous; George T De Sanctis; George Desanctis; Stephen Underwood; Michael Graupe; Richard A Flavell; John A Schmidt; Jack A Elias
Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8106-15.
2005: Jack A Elias; Chun Geun Lee
Lipid let loose in pulmonary emphysema.
Nature medicine 2005;11(5):471-2.
2005: Chuan Hua He; Aaron B Waxman; Chun Geun Lee; Holger W Link; Morgan E Rabach; Bing Ma; Qingsheng Chen; Zhou Zhu; Mei Zhong; Keiko Nakayama; Keiichi I Nakayama; Robert J Homer; Jack A Elias
Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury.
The Journal of clinical investigation 2005;115(4):1039-48.
2005: Qingsheng Chen; Lesley A Rabach; Paul Noble; Tao Zheng; Chun Geun Lee; Robert J Homer; Jack A Elias
IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):2305-13.
2004: Alfin Vicencio IV; Chun Geun Lee; Soo Jung Cho; Oliver Eickelberg; Ying Chuu; Gabriel G Haddad; Jack A Elias
Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia?
American journal of respiratory cell and molecular biology 2004;31(6):650-6.
2004: Peter Baluk; Chun Geun Lee; Holger W Link; Erin Ator; Amy Haskell; Jack A Elias; Donald M McDonald
Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways.
The American journal of pathology 2004;165(4):1071-85.
2004: Chun Geun Lee; Holger W Link; Peter Baluk; Robert J Homer; Svetlana Chapoval; Vineet Bhandari; Min Jong Kang; Lauren Cohn; Yoon-Keun Kim; Donald M McDonald; Jack A Elias
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.
Nature medicine 2004;10(10):1095-103.
2004: Chun Geun Lee; Soo Jung Cho; Min Jong Kang; Svetlana Chapoval; Patty J Lee; Paul W Noble; Teshome Yehualaeshet; Binfeng Lu; Richard A Flavell; Jeffrey Milbrandt; Robert J Homer; Jack A Elias
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis.
The Journal of experimental medicine 2004;200(3):377-89.
2003: Geun Tae Park; Oh Young Lee; Sung Joon Kwon; Chun Geun Lee; Byung Chul Yoon; Joon Soo Hahm; Min Ho Lee; Dong Hoo Lee; Choon Suhk Kee; Hee Sik Sun
Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans.
Journal of gastroenterology and hepatology 2003;18(11):1257-63.
2003: Jingming Wang; Qingsheng Chen; Jonathan Corne; Zhou Zhu; Chun Geun Lee; Vineet Bhandari; Robert J Homer; Jack A Elias
Pulmonary expression of leukemia inhibitory factor induces B cell hyperplasia and confers protection in hyperoxia.
The Journal of biological chemistry 2003;278(33):31226-32.
2003: Janci Chunn Lindsay; Chun Geun Lee; Hays W J Young; Zhou Zhu; Janci L Chunn; Min Jong Kang; Suman K Banerjee; Jack A Elias
Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway.
The Journal of clinical investigation 2003;112(3):332-44.
2003: Tao Zheng; Zhou Zhu; Wei Liu; Chun Geun Lee; Qingsheng Chen; Robert J Homer; Jack A Elias
Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro.
The Journal of allergy and clinical immunology 2003;111(4):720-8.
2003: Jack A Elias; Chun Geun Lee; Tao Zheng; Yun Shim; Zhou Zhu
Interleukin-13 and leukotrienes: an intersection of pathogenetic schema.
American journal of respiratory cell and molecular biology 2003;28(4):401-4.
2003: Jack A Elias; Tao Zheng; Chun Geun Lee; Robert J Homer; Qingsheng Chen; Bing Ma; Michael Blackburn; Zhou Zhu
Transgenic modeling of interleukin-13 in the lung.
Chest 2003;123(3 Suppl):339S-45S.
2003: Jack A Elias; Chun Geun Lee; Tao Zheng; Bing Ma; Robert J Homer; Zhou Zhu
New insights into the pathogenesis of asthma.
The Journal of clinical investigation 2003;111(3):291-7.
2002: Chun Geun Lee; Robert J Homer; Lauren Cohn; Holger W Link; Sungsoo Jung; Joseph E Craft; Barney S Graham; Teresa Johnson; Jack A Elias
Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways.
The Journal of biological chemistry 2002;277(38):35466-74.
2002: Sophie Lanone; Tao Zheng; Zhou Zhu; Wei Liu; Chun Geun Lee; Bing Ma; Qingsheng Chen; Robert J Homer; Jingming Wang; Lesley A Rabach; Morgan E Rabach; J Michael Shipley; Steven D Shapiro; Robert M Senior; Jack A Elias
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling.
The Journal of clinical investigation 2002;110(4):463-74.
2002: Zhou Zhu; Tao Zheng; Chun Geun Lee; Robert J Homer; Jack A Elias
Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling.
Seminars in cell & developmental biology 2002;13(2):121-8.
2002: Zhou Zhu; Bing Ma; Tao Zheng; Robert J Homer; Chun Geun Lee; Israel F Charo; Paul Noble; Jack A Elias
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2953-62.
2001: Zhou Zhu; Chun Geun Lee; Tao Zheng; Geoffrey L Chupp; Jingming Wang; Robert J Homer; Paul W Noble; Qutayba Hamid; Jack A Elias
Airway inflammation and remodeling in asthma. Lessons from interleukin 11 and interleukin 13 transgenic mice.
American journal of respiratory and critical care medicine 2001;164(10 Pt 2):S67-70.
2001: Chun Geun Lee; Robert J Homer; Zhou Zhu; Sophie Lanone; X Wang; V Koteliansky; J Michael Shipley; Philip J Gotwals; Paul Noble; Quingshen Chen; Robert M Senior; Jack A Elias
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).
The Journal of experimental medicine 2001;194(6):809-21.
2000: Chun Geun Lee; Ho Joo Yoon; Zhou Zhu; Holger W Link; Z Wang; JM Gwaltney; M Landry; Jack A Elias
Respiratory syncytial virus stimulation of vascular endothelial cell growth Factor/Vascular permeability factor.
American journal of respiratory cell and molecular biology 2000;23(5):662-9.
2000: J Corne; Geoffrey L Chupp; Chun Geun Lee; Robert J Homer; Zhou Zhu; Quingshen Chen; Bing Ma; Y Du; F Roux; J McArdle; Aaron B Waxman; Jack A Elias
IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury.
The Journal of clinical investigation 2000;106(6):783-91.
2000: Jingming Wang; Robert J Homer; L Hong; Lauren Cohn; Chun Geun Lee; S Jung; Jack A Elias
IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):2222-31.
1999: Chetankumar S Tailor; A Nouri; Chun Geun Lee; C Kozak; David Kabat
Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(3):927-32.