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Michael Chopp

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Hongqi Xin; Li Zhang; Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp; Li Hong Shen; Yi Li
Multipotent mesenchymal stromal cells decrease transforming growth factor β1 expression in microglia/macrophages and down-regulate plasminogen activator inhibitor 1 expression in astrocytes after stroke.
Xian Shuang Liu; Tao Tang; Xin Li Wang; Jennifer Xu; Li Zhang; Rui Lan Zhang; Charles Chen; Michael Chopp; Ann Hozeska-Solgot; Haifa Kassis; Zheng Gang Zhang
MicroRNA-17-92 Cluster Mediates the Proliferation and Survival of Neural Progenitor Cells after Stroke.
Yi Zhang; Benjamin Buller; Michael Chopp; Xian Shuang Liu; Yuji Ueno; Xinli Wang; Zheng Gang Zhang
The MicroRNA-17-92 Cluster Enhances Axonal Outgrowth in Embryonic Cortical Neurons.

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All Publications

2013: Hongqi Xin; Li Zhang; Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp; Li Hong Shen; Yi Li
Multipotent mesenchymal stromal cells decrease transforming growth factor β1 expression in microglia/macrophages and down-regulate plasminogen activator inhibitor 1 expression in astrocytes after stroke.
Neuroscience letters 2013;542():81-6.
2013: Xian Shuang Liu; Tao Tang; Xin Li Wang; Jennifer Xu; Li Zhang; Rui Lan Zhang; Charles Chen; Michael Chopp; Ann Hozeska-Solgot; Haifa Kassis; Zheng Gang Zhang
MicroRNA-17-92 Cluster Mediates the Proliferation and Survival of Neural Progenitor Cells after Stroke.
The Journal of biological chemistry 2013;288(18):12478-88.
2013: Yi Zhang; Benjamin Buller; Michael Chopp; Xian Shuang Liu; Yuji Ueno; Xinli Wang; Zheng Gang Zhang
The MicroRNA-17-92 Cluster Enhances Axonal Outgrowth in Embryonic Cortical Neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(16):6885-94.
2013: Xuguang Zheng; Yong Lu; Benjamin Buller; Michael Chopp; Feng Jiang
MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3.
Cancer letters 2013;329(2):146-54.
2013: Ye Xiong; Asim Mahmood; Michael Chopp
Animal models of traumatic brain injury.
Nature reviews. Neuroscience 2013;14(2):128-42.
2013: Asim Mahmood; Changsheng Qu; Hongtao Wu; Ye Xiong; Michael Chopp
Effects of treating traumatic brain injury with collagen scaffolds and human bone marrow stromal cells on sprouting of corticospinal tract axons into the denervated side of the spinal cord.
Journal of neurosurgery 2013;118(2):381-9.
2013: Guang Liang Ding; John S Budaj; Michael Chopp; Lian Li; Qingjiang Li; Asim Mahmood; Siamak P Nejad-Davarani; David J Poulsen; Changsheng Qu; Hongtao Wu; Quan Jiang
MRI of neuronal recovery after low-dose methamphetamine treatment of traumatic brain injury in rats.
PloS one 2013;8(4):e61241.
2013: Amjad Shehadah; Alex Zacharek; Jieli Chen; Yisheng Cui; Brian Kramer; Mei Lu; Cynthia Roberts; Michael Chopp
Efficacy of single and multiple injections of human umbilical tissue-derived cells following experimental stroke in rats.
PloS one 2013;8(1):e54083.
2013: Xu Cui; Yisheng Cui; Cynthia Roberts; Alex Zacharek; Michael Chopp; Jieli Chen
The neurorestorative benefit of GW3965 treatment of stroke in mice.
Stroke; a journal of cerebral circulation 2013;44(1):153-61.
2013: Yong Lu; Xuguang Zheng; Benjamin Buller; Michael Chopp; Mark Katakowski; Feng Jiang
MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells.
Oncology reports 2013;29(1):67-72.
2012: Xu Cui; J Dai; N Kuzmin-Nichols; R Ning; Cynthia Roberts; Cyndy Davis Sanberg; A Shehadah; T Yan; Alex Zacharek; C Zhang; Michael Chopp; Jieli Chen
Combination treatment of stroke with sub-therapeutic doses of Simvastatin and human umbilical cord blood cells enhances vascular remodeling and improves functional outcome.
Neuroscience 2012;227():223-31.
2012: Li Zhang; Michael Chopp; Anna Gosiewska; Brian C Kramer; Yi Li; Michael Romanko; Klaudyne Hong
Different routes of administration of human umbilical tissue-derived cells improve functional recovery in the rat after focal cerebral ischemia.
Brain research 2012;1489():104-12.
2012: Manoranjan Santra; Soumi Santra; Sutapa Santra; Zheng Gang Zhang; Michael Chopp; Mei Lu; Ankita Nalani; Daniel C Morris
Thymosin beta 4 mediates oligodendrocyte differentiation by upregulating p38 MAPK.
Glia 2012;60(12):1826-38.
2012: Lei Wang; Jing Zhang; Li Zhang; Rui Lan Zhang; Michael Chopp; Zhongwu Liu; Mei Lu; Dan Morris; Alexandra Szalad; Zheng Gang Zhang
Thymosin β4 promotes the recovery of peripheral neuropathy in type II diabetic mice.
Neurobiology of disease 2012;48(3):546-55.
2012: Benjamin Buller; Michael Chopp; Daniel Morris; Yuji Ueno; Li Zhang; Rui Lan Zhang; Yi Zhang; Zheng Gang Zhang
Regulation of serum response factor by miRNA-200 and miRNA-9 modulates oligodendrocyte progenitor cell differentiation.
Glia 2012;60(12):1906-14.
2012: Hongtao Wu; Ye Xiong; Asim Mahmood; Changsheng Qu; Michael Chopp
Simvastatin attenuates axonal injury after experimental traumatic brain injury and promotes neurite outgrowth of primary cortical neurons.
Brain research 2012;1486():121-30.
2012: Lian Li; Qing Jiang Li; Mei Lu; Asim Mahmood; Siamak P Nejad-Davarani; Chang Sheng Qu; Shiyang Wang; Michael Chopp; Guang Liang Ding; Quan Jiang
MRI measurement of angiogenesis and the therapeutic effect of acute marrow stromal cell administration on traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(11):2023-32.
2012: Philip Lazarovici; Chunling Zhang; Hadar Arien-Zakay; Jieli Chen; Michael Chopp; Gadi Cohen; Hao Jiang
Multimodal neuroprotection induced by PACAP38 in oxygen-glucose deprivation and middle cerebral artery occlusion stroke models.
Journal of molecular neuroscience : MN 2012;48(3):526-40.
2012: R Ning; Cynthia Roberts; T Yan; Alex Zacharek; C Zhang; Michael Chopp; X Cui; Mei Lu; Jieli Chen
Tissue plasminogen activator treatment of stroke in type-1 diabetes rats.
Neuroscience 2012;222():326-32.
2012: Ye Xiong; Yanlu Zhang; Zheng Gang Zhang; Asim Mahmood; Yuling Meng; Daniel C Morris; Michael Chopp
Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury.
Annals of the New York Academy of Sciences 2012;1270():51-8.
2012: Daniel C Morris; Ye Xiong; Jing Zhang; Li Zhang; Zheng G Zhang; Michael Chopp
Treatment of neurological injury with thymosin β4.
Annals of the New York Academy of Sciences 2012;1269():110-6.
2012: X S Liu; Rui Lan Zhang; C Chen; Michael Chopp; Y S Cui; A Hozeska-Solgot; L F Jia; H Kassis; Zheng Gang Zhang
Valproic acid increases white matter repair and neurogenesis after stroke.
Neuroscience 2012;220():313-21.
2012: Yaoming Wang; Zhenggang Zhang; Michael Chopp; Nienwen Chow; Thomas P Davis; John H Griffin; Berislav V Zlokovic
An activated protein C analog with reduced anticoagulant activity extends the therapeutic window of tissue plasminogen activator for ischemic stroke in rodents.
Stroke; a journal of cerebral circulation 2012;43(9):2444-9.
2012: Kirit Pindolia; Cisley Cardwell; Jieli Chen; Michael Chopp; Xu Cui; Barry Wolf
Neurological deficits in mice with profound biotinidase deficiency are associated with demylination and axonal degeneration.
Neurobiology of disease 2012;47(3):428-35.
2012: Li Zhang; Michael Chopp; Haifa Kassis; Xianshuang Liu; Tao Tang; Hua Teng; Zheng Gang Zhang
Combination therapy with VELCADE and tissue plasminogen activator is neuroprotective in aged rats after stroke and targets microRNA-146a and the toll-like receptor signaling pathway.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(8):1856-64.
2012: Yuji Ueno; Li Zhang; Yi Zhang; Benjamin Buller; Michael Chopp; Norman Lehman; Xian Shuang Liu; Zhongwu Liu; Cynthia Roberts; Zheng Gang Zhang
Axonal outgrowth and dendritic plasticity in the cortical peri-infarct area after experimental stroke.
Stroke; a journal of cerebral circulation 2012;43(8):2221-8.
2012: Li Zhang; Zheng Gang Zhang; Michael Chopp
The neurovascular unit and combination treatment strategies for stroke.
Trends in pharmacological sciences 2012;33(8):415-22.
2012: Evgeniy Khain; Nicholas Charteris; Feng Jiang; Mark Katakowski; Michael Chopp
Migration of adhesive glioma cells: front propagation and fingering.
Physical review. E, Statistical, nonlinear, and soft matter physics 2012;86(1 Pt 1):011904.
2012: Hongqi Xin; Yi Zhang; Zheng Gang Zhang; Ben Buller; Mark Katakowski; Yi Li; Xia Shang; Xinli Wang; Michael Chopp
Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth.
Stem cells (Dayton, Ohio) 2012;30(7):1556-64.
2012: Yanlu Zhang; Michael Chopp; Asim Mahmood; Yuling Meng; Changsheng Qu; Ye Xiong
Impact of inhibition of erythropoietin treatment-mediated neurogenesis in the dentate gyrus of the hippocampus on restoration of spatial learning after traumatic brain injury.
Experimental neurology 2012;235(1):336-44.
2012: Ye Xiong; Yanlu Zhang; Zheng Gang Zhang; Asim Mahmood; Yuling Meng; Daniel C Morris; Michael Chopp
Neuroprotective and neurorestorative effects of thymosin β4 treatment initiated 6 hours after traumatic brain injury in rats.
Journal of neurosurgery 2012;116(5):1081-92.
2012: Dirk M Hermann; Michael Chopp
Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation.
Lancet neurology 2012;11(4):369-80.
2012: Tao Yan; Xinchun Ye; Alex Zacharek; Ben Buller; Michael Chopp; Yisheng Cui; Zhongwu Liu; Cynthia Roberts; Jieli Chen
Niaspan increases axonal remodeling after stroke in type 1 diabetes rats.
Neurobiology of disease 2012;46(1):157-64.
2012: Dongmei Yang; Jianfeng Zhang; Michael Chopp; Yuxia Han; Agnieszka Seyda; Donald Seyfried
Therapeutic effect of human umbilical tissue-derived cell treatment in rats with experimental intracerebral hemorrhage.
Brain research 2012;1444():1-10.
2012: Zhongwu Liu; Hongqi Xin; Li Zhang; Yisheng Cui; William H Frey; Leah R Hanson; Yi Li; Michael Chopp
Subacute intranasal administration of tissue plasminogen activator increases functional recovery and axonal remodeling after stroke in rats.
Neurobiology of disease 2012;45(2):804-9.
2012: Xuguang Zheng; Mark Katakowski; Feng Jiang; Yong Lu; Michael Chopp
ADAM17 promotes glioma cell malignant phenotype.
Molecular carcinogenesis 2012;51(2):150-64.
2012: Arbab Ali; Klaudyne Hong; A S M Iskander; Quan Jiang; Bradford Navia; Christine Thiffault; Nadimpalli Rs Varma; Stephen J Victor; Li Zhang; Michael Chopp
Tracking of In-111-labeled human umbilical tissue-derived cells (hUTC) in a rat model of cerebral ischemia using SPECT imaging.
BMC medical imaging 2012;12():33.
2012: Rui Lan Zhang; Michael Chopp; Xianshuang Liu; Mei Lu; Cynthia Roberts; Xinli Wang; Min Wei; Zheng Gang Zhang
Sildenafil enhances neurogenesis and oligodendrogenesis in ischemic brain of middle-aged mouse.
PloS one 2012;7(10):e48141.
2012: Quan Jiang; Brian C Kramer; Lian Li; Qing Jiang Li; Yi Li; Mei Lu; Brad Navia; Siamak P Nejad-Davarani; Christine Thiffault; Stephen J Victor; Shi Yang Wang; Li Zhang; Arbab Ali; Guang Liang Ding; Klaudyne Hong; Michael Chopp
MRI detects brain reorganization after human umbilical tissue-derived cells (hUTC) treatment of stroke in rat.
PloS one 2012;7(8):e42845.
2012: Sang-Hun Bae; Michael Chopp; Kwan Soo Hong; Myung Seo Kang; Kyung-Sul Kim; Tae-Ho Kong; Hyun-Seob Lee; Jisook Moon
Long-lasting paracrine effects of human cord blood cells on damaged neocortex in an animal model of cerebral palsy.
Cell transplantation 2012;21(11):2497-515.
2012: Hua Teng; Michael Chopp; Ann Hozeska-Solgot; Mei Lu; Lihong Shen; Clark Tang; Zheng Gang Zhang
Tissue plasminogen activator and plasminogen activator inhibitor 1 contribute to sonic hedgehog-induced in vitro cerebral angiogenesis.
PloS one 2012;7(3):e33444.
2012: Xu Cui; Junhao Dai; Nicole Kuzmin-Nichols; Cynthia Roberts; Cyndy Davis Sanberg; Amjad Shehadah; Yuji Ueno; Alex Zacharek; Chunling Zhang; Michael Chopp; Jieli Chen
Therapeutic benefit of treatment of stroke with simvastatin and human umbilical cord blood cells: neurogenesis, synaptic plasticity, and axon growth.
Cell transplantation 2012;21(5):845-56.
2012: Hala Darwish; Michael Chopp; Hala Dawish; Asim Mahmood; Timothy Schallert; Barbara Therrien
Mild traumatic brain injury (MTBI) leads to spatial learning deficits.
Brain injury : [BI] 2012;26(2):151-65.
2011: Xinchun Ye; Alex Zacharek; Michael Chopp; Xu Cui; Yisheng Cui; Xinfeng Liu; Mei Lu; Cynthia Roberts; Amjad Shehadah; Tao Yan; Jieli Chen
Niaspan enhances vascular remodeling after stroke in type 1 diabetic rats.
Experimental neurology 2011;232(2):299-308.
2011: Jieli Chen; Xu Cui; Yishen Cui; Xiangguo Dai; Xinfeng Liu; Mei Lu; Cynthia Roberts; Tao Yan; Xiao-Ping Yang; Xinchun Ye; Alex Zacharek; Chunling Zhang; Michael Chopp
Adverse effects of bone marrow stromal cell treatment of stroke in diabetic rats.
Stroke; a journal of cerebral circulation 2011;42(12):3551-8.
2011: Guangliang Ding; James R Ewing; Steven Gu; Quan Jiang; Lian Li; Qingjiang Li; Mei Lu; Li Zhang; Zheng Gang Zhang; Michael Chopp
Longitudinal magnetic resonance imaging of sildenafil treatment of embolic stroke in aged rats.
Stroke; a journal of cerebral circulation 2011;42(12):3537-41.
2011: Xuguang Zheng; Michael Chopp; Christopher Ding; James Jiang; Yong Lu; Hongyan Yang; Li Zhang; Danping Zhao; Feng Jiang
Atorvastatin reduces functional deficits caused by photodynamic therapy in rats.
International journal of oncology 2011;39(5):1133-41.
2011: Hongqi Xin; Rui Lan Zhang; Zheng Gang Zhang; Ann Hozeska-Solgot; Yi Li; Xianshuang Liu; Li Hong Shen; Michael Chopp
Multipotent mesenchymal stromal cells increase tPA expression and concomitantly decrease PAI-1 expression in astrocytes through the sonic hedgehog signaling pathway after stroke (in vitro study).
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(11):2181-8.
2011: Huijie Wei; Yong Xu; Long Yin; Jieli Chen; Michael Chopp; Jingfei Dong; Yimu Fan; Rongcai Jiang; Li Liu; Qun Mao; Jianning Zhang
Changes and function of circulating endothelial progenitor cells in patients with cerebral aneurysm.
Journal of neuroscience research 2011;89(11):1822-8.
2011: Quan Jiang; David Kaplan; Zhifeng Kou; Lian Li; Qingjiang Li; Mei Lu; Michael Chopp; Siamak P Nejad- Davarani; Guang Liang Ding; Joseph A Helpern; Jiani Hu; Jens H Jensen; Changsheng Qu; Yimin Shen; Shiyang Wang; Zheng Gang Zhang; Asim Mahmood
MRI evaluation of axonal reorganization after bone marrow stromal cell treatment of traumatic brain injury.
NMR in biomedicine 2011;24(9):1119-28.
2011: Amjad Shehadah; Li Zhang; Jieli Chen; Yisheng Cui; Mei Lu; Cynthia Roberts; Michael Chopp
Combination treatment with low-dose Niaspan and tissue plasminogen activator provides neuroprotection after embolic stroke in rats.
Journal of the neurological sciences 2011;309(1-2):96-101.
2011: Lei Wang; Li Zhang; Rui Lan Zhang; F M Alvarez; M Bolz; Michael Chopp; Yisheng Cui; Zhongwu Liu; Mei Lu; A Szalad; Zheng Gang Zhang
Phosphodiesterase-5 is a therapeutic target for peripheral neuropathy in diabetic mice.
Neuroscience 2011;193():399-410.
2011: X Ye; Alex Zacharek; Michael Chopp; X Cui; X Liu; Cynthia Roberts; T Yan; Jieli Chen
Niaspan reduces high-mobility group box 1/receptor for advanced glycation endproducts after stroke in type-1 diabetic rats.
Neuroscience 2011;190():339-45.
2011: Thomas F Rau; Sarah Ulatowski; Li Zhang; Diane M Brooks; Fernando Cardozo-Pelaez; Michael Chopp; Saskia Jacobson; Aakriti Kothiwal; David Poulsen
Low dose methamphetamine mediates neuroprotection through a PI3K-AKT pathway.
Neuropharmacology 2011;61(4):677-86.
2011: Yuling Meng; Changsheng Qu; Ye Xiong; Yanlu Zhang; Asim Mahmood; Michael Chopp
Dose-dependent neurorestorative effects of delayed treatment of traumatic brain injury with recombinant human erythropoietin in rats.
Journal of neurosurgery 2011;115(3):550-60.
2011: Xu Cui; Michael Chopp; Alex Zacharek; Xinchun Ye; Cynthia Roberts; Jieli Chen
Angiopoietin/Tie2 pathway mediates type 2 diabetes induced vascular damage after cerebral stroke.
Neurobiology of disease 2011;43(1):285-92.
2011: Manoranjan Santra; Sutapa Santra; Ben Buller; Ankita Nallani; Kastuv Santra; Michael Chopp
Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells.
Cancer science 2011;102(7):1350-7.
2011: Asim Mahmood; Riuzuo Ning; Changsheng Qu; Hongtao Wu; Ye Xiong; Anton Goussev; Susan Irtenkauf; Yi Li; Michael Chopp
Treatment of TBI with collagen scaffolds and human marrow stromal cells increases the expression of tissue plasminogen activator.
Journal of neurotrauma 2011;28(7):1199-207.
2011: Li Zhang; Yi Li; Chunling Zhang; Michael Chopp; Anna Gosiewska; Klaudyne Hong
Delayed administration of human umbilical tissue-derived cells improved neurological functional recovery in a rodent model of focal ischemia.
Stroke; a journal of cerebral circulation 2011;42(5):1437-44.
2011: Yong Lu; Feng Jiang; Xuguang Zheng; Mark Katakowski; Benjamin Buller; Shing Shun Tony To; Michael Chopp
TGF-β1 promotes motility and invasiveness of glioma cells through activation of ADAM17.
Oncology reports 2011;25(5):1329-35.
2011: Hongtao Wu; Ye Xiong; Dong Zhou; Changsheng Qu; Michael Chopp; Hao Jiang; Dunyue Lu; Asim Mahmood
Induction of angiogenesis and modulation of vascular endothelial growth factor receptor-2 by simvastatin after traumatic brain injury.
Neurosurgery 2011;68(5):1363-71; discussion 1371.
2011: Ruizhuo Ning; Ye Xiong; Asim Mahmood; Yanlu Zhang; Yuling Meng; Changsheng Qu; Michael Chopp
Erythropoietin promotes neurovascular remodeling and long-term functional recovery in rats following traumatic brain injury.
Brain research 2011;1384():140-50.
2011: Lian Li; Quan Jiang; Chang Sheng Qu; Guang Liang Ding; Qing Jiang Li; Shi Yang Wang; Ji Hyun Lee; Mei Lu; Asim Mahmood; Michael Chopp
Transplantation of marrow stromal cells restores cerebral blood flow and reduces cerebral atrophy in rats with traumatic brain injury: in vivo MRI study.
Journal of neurotrauma 2011;28(4):535-45.
2011: Dongmei Yang; Robert A Knight; Yuxia Han; Kishor Karki; Jianfeng Zhang; Christopher Ding; Michael Chopp; Donald Seyfried
Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: magnetic resonance imaging and histological study.
Journal of neurosurgery 2011;114(4):1135-42.
2011: Asamoah Bosomtwi; Michael Chopp; Li Zhang; Zheng Gang Zhang; Mei Lu; Quan Jiang
Mean microvessel segment length and radius after embolic stroke: Comparison of magnetic resonance imaging (MRI) and laser scanning confocal microscopy (LSCM).
Brain research 2011;1381():217-27.
2011: Evgeniy Khain; Mark Katakowski; Scott Hopkins; Alexandra Szalad; Xuguang Zheng; Feng Jiang; Michael Chopp
Collective behavior of brain tumor cells: the role of hypoxia.
Physical review. E, Statistical, nonlinear, and soft matter physics 2011;83(3 Pt 1):031920.
2011: Zhongwu Liu; Yi Li; Rui Lan Zhang; Yisheng Cui; Michael Chopp
Bone marrow stromal cells promote skilled motor recovery and enhance contralesional axonal connections after ischemic stroke in adult mice.
Stroke; a journal of cerebral circulation 2011;42(3):740-4.
2011: Sean I Savitz; Michael Chopp; Robert Deans; S T Carmichael; Donald Phinney; Larry Wechsler
Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II.
Stroke; a journal of cerebral circulation 2011;42(3):825-9.
2011: Li Hong Shen; Hongqi Xin; Yi Li; Rui Lan Zhang; Yisheng Cui; Li Zhang; Mei Lu; Zheng Gang Zhang; Michael Chopp
Endogenous tissue plasminogen activator mediates bone marrow stromal cell-induced neurite remodeling after stroke in mice.
Stroke; a journal of cerebral circulation 2011;42(2):459-64.
2011: Jieli Chen; Xu Cui; Alex Zacharek; Yisheng Cui; Cynthia Roberts; Michael Chopp
White matter damage and the effect of matrix metalloproteinases in type 2 diabetic mice after stroke.
Stroke; a journal of cerebral circulation 2011;42(2):445-52.
2011: Ye Xiong; Asim Mahmood; Yanlu Zhang; Yuling Meng; Zheng Gang Zhang; Changsheng Qu; Thomas N Sager; Michael Chopp
Effects of posttraumatic carbamylated erythropoietin therapy on reducing lesion volume and hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome in rats following traumatic brain injury.
Journal of neurosurgery 2011;114(2):549-59.
2011: Rui Lan Zhang; Michael Chopp; Cindi Roberts; Longfei Jia; Min Wei; Mei Lu; Xinli Wang; Siamak Pourabdollah; Zheng Gang Zhang
Ascl1 lineage cells contribute to ischemia-induced neurogenesis and oligodendrogenesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(2):614-25.
2011: Lei Wang; Michael Chopp; Hua Teng; Marianne Bolz; Moniche Ãlvarez Francisco; Danielle Marie Aluigi; Xin Li Wang; Rui Lan Zhang; Søren Chrsitensen; Thomas N Sager; Alexandra Szalad; Moniche-Alvarez Francisco; Zheng Gang Zhang
Tumor necrosis factor α primes cerebral endothelial cells for erythropoietin-induced angiogenesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(2):640-7.
2011: Changsheng Qu; Asim Mahmood; Xian Shuang Liu; Ye Xiong; Lei Wang; Hongtao Wu; Bo Li; Zheng Gang Zhang; David L Kaplan; Michael Chopp
The treatment of TBI with human marrow stromal cells impregnated into collagen scaffold: functional outcome and gene expression profile.
Brain research 2011;1371():129-39.
2011: Xian Shuang Liu; Tang Tao; Xin Li Wang; Li Zhang; Rui Lan Zhang; Charles Chen; Michael Chopp; Ann Hozeska-Solgot; Haifa Kassis; Zheng Gang Zhang
MicroRNA profiling in subventricular zone after stroke: MiR-124a regulates proliferation of neural progenitor cells through Notch signaling pathway.
PloS one 2011;6(8):e23461.
2011: Hassan Bagher-Ebadian; Michael Chopp; Kourosh Jafari-Khouzani; Mei Lu; Panayiotis Mitsias; Hamid Soltanian-Zadeh; James R Ewing
Predicting final extent of ischemic infarction using artificial neural network analysis of multi-parametric MRI in patients with stroke.
PloS one 2011;6(8):e22626.
2011: Ye Xiong; Asim Mahmood; Yuling Meng; Yanlu Zhang; Zheng Gang Zhang; Daniel C Morris; Michael Chopp
Treatment of traumatic brain injury with thymosin β₄ in rats.
Journal of neurosurgery 2011;114(1):102-15.
2010: Mark Katakowski; Xuguang Zheng; Feng Jiang; Thomas Rogers; Alexandra Szalad; Michael Chopp
MiR-146b-5p suppresses EGFR expression and reduces in vitro migration and invasion of glioma.
Cancer investigation 2010;28(10):1024-30.
2010: Chunling Zhang; Michael Chopp; Yisheng Cui; Lei Wang; Ruilan Zhang; Li Zhang; Mei Lu; Alexandra Szalad; Edith Doppler; Monika Hitzl; Zheng Gang Zhang
Cerebrolysin enhances neurogenesis in the ischemic brain and improves functional outcome after stroke.
Journal of neuroscience research 2010;88(15):3275-81.
2010: Kishor Karki; Robert A Knight; Li Hong Shen; Alissa Kapke; Mei Lu; Yi Li; Michael Chopp
Chronic brain tissue remodeling after stroke in rat: a 1-year multiparametric magnetic resonance imaging study.
Brain research 2010;1360():168-76.
2010: Ye Xiong; Asim Mahmood; Michael Chopp
Neurorestorative treatments for traumatic brain injury.
Discovery medicine 2010;10(54):434-42.
2010: Mark Katakowski; Benjamin Buller; Xinli Wang; Thomas Rogers; Michael Chopp
Functional microRNA is transferred between glioma cells.
Cancer research 2010;70(21):8259-63.
2010: Guangliang Ding; Quan Jiang; Lian Li; Li Zhang; Ying Wang; Zheng Gang Zhang; Mei Lu; Swayamprava Panda; Qingjiang Li; James R Ewing; Michael Chopp
Cerebral tissue repair and atrophy after embolic stroke in rat: a magnetic resonance imaging study of erythropoietin therapy.
Journal of neuroscience research 2010;88(14):3206-14.
2010: Quan Jiang; Zheng Gang Zhang; Michael Chopp
MRI evaluation of white matter recovery after brain injury.
Stroke; a journal of cerebral circulation 2010;41(10 Suppl):S112-3.
2010: Ben Buller; Xianshuang Liu; Xinli Wang; Rui L Zhang; Li Zhang; Ann Hozeska-Solgot; Michael Chopp; Zheng Gang Zhang
MicroRNA-21 protects neurons from ischemic death.
The FEBS journal 2010;277(20):4299-307.
2010: Amjad Shehadah; Jieli Chen; Alex Zacharek; Yisheng Cui; Madalina Ion; Cynthia Roberts; Alissa Kapke; Michael Chopp
Niaspan treatment induces neuroprotection after stroke.
Neurobiology of disease 2010;40(1):277-83.
2010: Yanlu Zhang; Ye Xiong; Asim Mahmood; Yuling Meng; Zhongwu Liu; Changsheng Qu; Michael Chopp
Sprouting of corticospinal tract axons from the contralateral hemisphere into the denervated side of the spinal cord is associated with functional recovery in adult rat after traumatic brain injury and erythropoietin treatment.
Brain research 2010;1353():249-57.
2010: Longfei Jia; Michael Chopp; Li Zhang; Mei Lu; Zheng Gang Zhang
Erythropoietin in combination of tissue plasminogen activator exacerbates brain hemorrhage when treatment is initiated 6 hours after stroke.
Stroke; a journal of cerebral circulation 2010;41(9):2071-6.
2010: Xu Cui; Michael Chopp; Alex Zacharek; Cynthia Roberts; Benjamin Buller; Madalina Ion; Jieli Chen
Niacin treatment of stroke increases synaptic plasticity and axon growth in rats.
Stroke; a journal of cerebral circulation 2010;41(9):2044-9.
2010: Changsheng Qu; Asim Mahmood; Ruizhuo Ning; Ye Xiong; Li Zhang; Jieli Chen; Hao Jiang; Michael Chopp
The treatment of traumatic brain injury with velcade.
Journal of neurotrauma 2010;27(9):1625-34.
2010: Yong Lu; Feng Jiang; Hao Jiang; Kalina Wu; Xuguang Zheng; Yizhong Cai; Mark Katakowski; Michael Chopp; Shing Shun Tony To
Gallic acid suppresses cell viability, proliferation, invasion and angiogenesis in human glioma cells.
European journal of pharmacology 2010;641(2-3):102-7.
2010: Hongtao Wu; Asim Mahmood; Dunyue Lu; Hao Jiang; Ye Xiong; Dong Zhou; Michael Chopp
Attenuation of astrogliosis and modulation of endothelial growth factor receptor in lipid rafts by simvastatin after traumatic brain injury.
Journal of neurosurgery 2010;113(3):591-7.
2010: Ye Xiong; Asim Mahmood; Yuling Meng; Yanlu Zhang; Changsheng Qu; Timothy Schallert; Michael Chopp
Delayed administration of erythropoietin reducing hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome following traumatic brain injury in rats: comparison of treatment with single and triple dose.
Journal of neurosurgery 2010;113(3):598-608.
2010: Daniel C Morris; Michael Chopp; Li Zhang; Mei Lu; Zheng Gang Zhang
Thymosin beta4 improves functional neurological outcome in a rat model of embolic stroke.
Neuroscience 2010;169(2):674-82.
2010: Amjad Shehadah; Jieli Chen; Xu Cui; Cynthia Roberts; Mei Lu; Michael Chopp
Combination treatment of experimental stroke with Niaspan and Simvastatin, reduces axonal damage and improves functional outcome.
Journal of the neurological sciences 2010;294(1-2):107-11.
2010: Li Hong Shen; Yi Li; Michael Chopp
Astrocytic endogenous glial cell derived neurotrophic factor production is enhanced by bone marrow stromal cell transplantation in the ischemic boundary zone after stroke in adult rats.
Glia 2010;58(9):1074-81.
2010: Zhongwu Liu; Yi Li; Zheng Gang Zhang; Xu Cui; Yisheng Cui; Mei Lu; Smita Savant-Bhonsale; Michael Chopp
Bone marrow stromal cells enhance inter- and intracortical axonal connections after ischemic stroke in adult rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(7):1288-95.
2010: Pietro Ghezzi; Myrian Bernaudin; Myriam Bernaudinb; Roberto Bianchi; Roberto Bianchic; Klas Blomgren; Michael Brines; Wendy Campana; Guido Cavaletti; Anthony Cerami; Michael Chopp; Thomas Coleman; Murat Digicaylioglu; Hannelore Ehrenreich; Serhat Erbayraktar; Zebeide Erbayraktar; Max Gassmann; Sermin Genc; Necati Gokmen; Giovanni Grasso; Sandra Juul; Stuart A Lipton; Carla Cerami Hand; Roberto Latini; Giuseppe Lauria; Marcel Leist; Samuel Sathyanesan Newton; Edwige Petit; Lesley Probert; Alessandra Sfacteria; Anna-Leena Siren; Mark Talan; Chris Thiemermann; Daan Westenbrink; Magdi Yaqoob; Changlian Zhu
Erythropoietin: not just about erythropoiesis.
Lancet 2010;375(9732):2142.
2010: Li Zhang; Zheng Gang Zhang; Ben Buller; James Jiang; Yanting Jiang; Danping Zhao; Xianshuang Liu; Dan Morris; Michael Chopp
Combination treatment with VELCADE and low-dose tissue plasminogen activator provides potent neuroprotection in aged rats after embolic focal ischemia.
Stroke; a journal of cerebral circulation 2010;41(5):1001-7.
2010: Daniel C Morris; Michael Chopp; Li Zhang; Zheng Gang Zhang
Thymosin beta4: a candidate for treatment of stroke?
Annals of the New York Academy of Sciences 2010;1194():112-7.
2010: Ye Xiong; Asim Mahmood; Michael Chopp
Angiogenesis, neurogenesis and brain recovery of function following injury.
Current opinion in investigational drugs (London, England : 2000) 2010;11(3):298-308.
2010: Alex Zacharek; Amjad Shehadah; Jieli Chen; Xu Cui; Cynthia Roberts; Mei Lu; Michael Chopp
Comparison of bone marrow stromal cells derived from stroke and normal rats for stroke treatment.
Stroke; a journal of cerebral circulation 2010;41(3):524-30.
2010: Lian Li; Quan Jiang; Guangliang Ding; Li Zhang; Zheng Gang Zhang; Qingjiang Li; Swayamprava Panda; Mei Lu; James R Ewing; Michael Chopp
Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(3):653-62.
2010: Quan Jiang; Zheng Gang Zhang; Michael Chopp
MRI of stroke recovery.
Stroke; a journal of cerebral circulation 2010;41(2):410-4.
2010: Manoranjan Santra; Xuguang Zheng; Cindi Roberts; Sutapa Santra; Mei Lu; Swayamprava Panda; Feng Jiang; Michael Chopp
Single doublecortin gene therapy significantly reduces glioma tumor volume.
Journal of neuroscience research 2010;88(2):304-14.
2010: Donald Seyfried; Yuxia Han; Dongmei Yang; Jennifer Ding; Li Hong Shen; Smita Savant-Bhonsale; Michael Chopp
Localization of bone marrow stromal cells to the injury site after intracerebral hemorrhage in rats.
Journal of neurosurgery 2010;112(2):329-35.
2010: Li Zhang; Michael Chopp; Rui Lan Zhang; Lei Wang; Jing Zhang; Ying Wang; Yier Toh; Manoranjan Santra; Mei Lu; Zheng Gang Zhang
Erythropoietin amplifies stroke-induced oligodendrogenesis in the rat.
PloS one 2010;5(6):e11016.
2010: Hongqi Xin; Yi Li; Li Hong Shen; Xianshuang Liu; Xinli Wang; Jing Zhang; Siamak Pourabdollah-Nejad D; Chunling Zhang; Li Zhang; Hao Jiang; Zheng Gang Zhang; Michael Chopp
Increasing tPA activity in astrocytes induced by multipotent mesenchymal stromal cells facilitate neurite outgrowth after stroke in the mouse.
PloS one 2010;5(2):e9027.
2010: Jian Xu; Xinfeng Liu; Jieli Chen; Alex Zacharek; Xu Cui; Smita Savant-Bhonsale; Michael Chopp; Zhenguo Liu
Cell-cell interaction promotes rat marrow stromal cell differentiation into endothelial cell via activation of TACE/TNF-alpha signaling.
Cell transplantation 2010;19(1):43-53.
2010: Jieli Chen; Alex Zacharek; Xu Cui; Amjad Shehadah; Hao Jiang; Cynthia Roberts; Mei Lu; Michael Chopp
Treatment of stroke with a synthetic liver X receptor agonist, TO901317, promotes synaptic plasticity and axonal regeneration in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(1):102-9.
2010: Ye Xiong; Asim Mahmood; Changsheng Qu; Humaira Kazmi; Zheng Gang Zhang; Constance T Noguchi; Timothy Schallert; Michael Chopp
Erythropoietin improves histological and functional outcomes after traumatic brain injury in mice in the absence of the neural erythropoietin receptor.
Journal of neurotrauma 2010;27(1):205-15.
2010: Hao Jiang; Xia Shang; Hongtao Wu; Grace Huang; Yiyang Wang; Shaza Al-Holou; Subhash C Gautam; Michael Chopp
Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells.
Neurochemical research 2010;35(1):152-61.
2009: Jing Zhang; Zheng Gang Zhang; D Morris; Yi Li; Cynthia Roberts; Stanton Elias; Michael Chopp
Neurological functional recovery after thymosin beta4 treatment in mice with experimental auto encephalomyelitis.
Neuroscience 2009;164(4):1887-93.
2009: Hongtao Wu; Hao Jiang; Dunyue Lu; Ye Xiong; Changsheng Qu; Dong Zhou; Asim Mahmood; Michael Chopp
Effect of simvastatin on glioma cell proliferation, migration, and apoptosis.
Neurosurgery 2009;65(6):1087-96; discussion 1096-7.
2009: Li Zhang; Michael Chopp; Longfei Jia; Yisheng Cui; Mei Lu; Zheng Gang Zhang
Atorvastatin extends the therapeutic window for tPA to 6 h after the onset of embolic stroke in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(11):1816-24.
2009: Yanlu Zhang; Ye Xiong; Asim Mahmood; Yuling Meng; Changsheng Qu; Timothy Schallert; Michael Chopp
Therapeutic effects of erythropoietin on histological and functional outcomes following traumatic brain injury in rats are independent of hematocrit.
Brain research 2009;1294():153-64.
2009: prateek karki; Robert A Knight; Yuxia Han; Dongmei Yang; Jianfeng Zhang; Karyn A Ledbetter; Michael Chopp; Donald Seyfried
Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2009;40(10):3384-9.
2009: Xu Cui; Michael Chopp; Alex Zacharek; Cynthia Roberts; Mei Lu; Smita Savant-Bhonsale; Jieli Chen
Chemokine, vascular and therapeutic effects of combination Simvastatin and BMSC treatment of stroke.
Neurobiology of disease 2009;36(1):35-41.
2009: Changsheng Qu; Ye Xiong; Asim Mahmood; David L Kaplan; Anton Goussev; Ruizhuo Ning; Michael Chopp
Treatment of traumatic brain injury in mice with bone marrow stromal cell-impregnated collagen scaffolds.
Journal of neurosurgery 2009;111(4):658-65.
2009: Brian Silver; Sharon McCarthy; Mei Lu; Panayiotis Mitsias; Andrew N Russman; Angelos Katramados; Daniel C Morris; Christopher Lewandowski; Michael Chopp
Sildenafil treatment of subacute ischemic stroke: a safety study at 25-mg daily for 2 weeks.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2009;18(5):381-3.
2009: Mark Katakowski; Feng Jiang; XuGuang Zheng; Jorge A Gutierrez; Alexandra Szalad; Michael Chopp
Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17.
Cancer science 2009;100(9):1597-604.
2009: Xin Hong; Feng Jiang; Steven N Kalkanis; Zheng Gang Zhang; Xuepeng Zhang; Xuguang Zheng; Hao Jiang; Michael Chopp
Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy.
Lasers in medical science 2009;24(5):777-86.
2009: Xian Shuang Liu; Michael Chopp; Rui Lan Zhang; Ann Hozeska-Solgot; Sara C Gregg; Ben Buller; Mei Lu; Zheng Gang Zhang
Angiopoietin 2 mediates the differentiation and migration of neural progenitor cells in the subventricular zone after stroke.
The Journal of biological chemistry 2009;284(34):22680-9.
2009: Donald Seyfried; Yuxia Han; D Yang; J Ding; Michael Chopp
Erythropoietin promotes neurological recovery after intracerebral haemorrhage in rats.
International journal of stroke : official journal of the International Stroke Society 2009;4(4):250-6.
2009: Xuepeng Zhang; Xuguang Zheng; Feng Jiang; Zheng Gang Zhang; Mark Katakowski; Michael Chopp
Dual-color fluorescence imaging in a nude mouse orthotopic glioma model.
Journal of neuroscience methods 2009;181(2):178-85.
2009: Asim Mahmood; Anton Goussev; Humaira Kazmi; Changsheng Qu; Dunyue Lu; Michael Chopp
Long-term benefits after treatment of traumatic brain injury with simvastatin in rats.
Neurosurgery 2009;65(1):187-91; discussion 191-2.
2009: Bo Li; Asim Mahmood; Dunyue Lu; Hongtao Wu; Ye Xiong; Changsheng Qu; Michael Chopp
Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury.
Neurosurgery 2009;65(1):179-85; discussion 185-6.
2009: Zhongwu Liu; Rui Lan Zhang; Yi Li; Yisheng Cui; Michael Chopp
Remodeling of the corticospinal innervation and spontaneous behavioral recovery after ischemic stroke in adult mice.
Stroke; a journal of cerebral circulation 2009;40(7):2546-51.
2009: Jieli Chen; Xu Cui; Alex Zacharek; Cynthia Roberts; Michael Chopp
eNOS mediates TO90317 treatment-induced angiogenesis and functional outcome after stroke in mice.
Stroke; a journal of cerebral circulation 2009;40(7):2532-8.
2009: Rui Lan Zhang; Michael Chopp; Sara R Gregg; Yier Toh; Cindi Roberts; Yvonne LeTourneau; Benjamin Buller; Longfei Jia; Siamak P Nejad Davarani; Zheng Gang Zhang
Patterns and dynamics of subventricular zone neuroblast migration in the ischemic striatum of the adult mouse.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(7):1240-50.
2009: Jieli Chen; Xu Cui; Alex Zacharek; Michael Chopp
Increasing Ang1/Tie2 expression by simvastatin treatment induces vascular stabilization and neuroblast migration after stroke.
Journal of cellular and molecular medicine 2009;13(7):1348-57.
2009: Yi Li; Michael Chopp
Marrow stromal cell transplantation in stroke and traumatic brain injury.
Neuroscience letters 2009;456(3):120-3.
2009: Xuguang Zheng; Feng Jiang; Mark Katakowski; Zheng Gang Zhang; Qing-e Lu; Michael Chopp
ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation.
Cancer biology & therapy 2009;8(11):1045-54.
2009: Jing Zhang; Yi Li; Zheng Gang Zhang; Mei Lu; Jade Borneman; Ben Buller; Smita Savant-Bhonsale; Stanton Elias; Michael Chopp
Bone marrow stromal cells increase oligodendrogenesis after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(6):1166-74.
2009: Michael Chopp; Asim Mahmood; Dunyue Lu; Yi Li
Editorial. Mesenchymal stem cell treatment of traumatic brain injury.
Journal of neurosurgery 2009;110(6):1186-8.
2009: Ye Xiong; Michael Chopp; Chuan-Pu Lee
Erythropoietin improves brain mitochondrial function in rats after traumatic brain injury.
Neurological research 2009;31(5):496-502.
2009: Zheng Gang Zhang; Michael Chopp
Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic.
Lancet neurology 2009;8(5):491-500.
2009: Jieli Chen; Xu Cui; Alex Zacharek; Guang Liang Ding; Amjad Shehadah; Quan Jiang; Mei Lu; Michael Chopp
Niaspan treatment increases tumor necrosis factor-alpha-converting enzyme and promotes arteriogenesis after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(5):911-20.
2009: Jing Zhang; Chaya Brodie; Yi Li; Xuguang Zheng; Cynthia Roberts; Mei Lu; Qi Gao; Jade Borneman; Smita Savant-Bhonsale; Stanton Elias; Michael Chopp
Bone marrow stromal cell therapy reduces proNGF and p75 expression in mice with experimental autoimmune encephalomyelitis.
Journal of the neurological sciences 2009;279(1-2):30-8.
2009: Ye Xiong; Changsheng Qu; Asim Mahmood; Zhongwu Liu; Ruizhuo Ning; Yi Li; David L Kaplan; Timothy Schallert; Michael Chopp
Delayed transplantation of human marrow stromal cell-seeded scaffolds increases transcallosal neural fiber length, angiogenesis, and hippocampal neuronal survival and improves functional outcome after traumatic brain injury in rats.
Brain research 2009;1263():183-91.
2009: Xu Cui; Michael Chopp; Alex Zacharek; C Zhang; Cynthia Roberts; Jieli Chen
Role of endothelial nitric oxide synthetase in arteriogenesis after stroke in mice.
Neuroscience 2009;159(2):744-50.
2009: Ye Xiong; Asim Mahmood; Michael Chopp
Emerging treatments for traumatic brain injury.
Expert opinion on emerging drugs 2009;14(1):67-84.
2009: Lian Li; Quan Jiang; Guangliang Ding; Li Zhang; Zheng Gang Zhang; Qingjiang Li; Swayamprava Panda; Alissa Kapke; Mei Lu; James R Ewing; Michael Chopp
MRI identification of white matter reorganization enhanced by erythropoietin treatment in a rat model of focal ischemia.
Stroke; a journal of cerebral circulation 2009;40(3):936-41.
2009: Jian Xu; Xinfeng Liu; Jieli Chen; Alex Zacharek; Xu Cui; Smita Savant-Bhonsale; Zhenguo Liu; Michael Chopp
Simvastatin enhances bone marrow stromal cell differentiation into endothelial cells via notch signaling pathway.
American journal of physiology. Cell physiology 2009;296(3):C535-43.
2009: Hemanthkumar Athiraman; Quan Jiang; Guang Liang Ding; Li Zhang; Zheng Gang Zhang; Lei Wang; Arbab Ali; Qingjiang Li; Swayamprava Panda; Karen Ledbetter; Ali M Rad; Michael Chopp
Investigation of relationships between transverse relaxation rate, diffusion coefficient, and labeled cell concentration in ischemic rat brain using MRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2009;61(3):587-94.
2009: Michael Chopp; Yi Li; Zheng Gang Zhang
Mechanisms underlying improved recovery of neurological function after stroke in the rodent after treatment with neurorestorative cell-based therapies.
Stroke; a journal of cerebral circulation 2009;40(3 Suppl):S143-5.
2009: Lei Wang; Michael Chopp; Rui Lan Zhang; Li Zhang; Yvonne LeTourneau; Y F Feng; A Jiang; D C Morris; Zheng Gang Zhang
The Notch pathway mediates expansion of a progenitor pool and neuronal differentiation in adult neural progenitor cells after stroke.
Neuroscience 2009;158(4):1356-63.
2009: Xian Shuang Liu; Michael Chopp; Xue Guo Zhang; Rui Lan Zhang; Ben Buller; Ann Hozeska-Solgot; Sara R Gregg; Zheng Gang Zhang
Gene profiles and electrophysiology of doublecortin-expressing cells in the subventricular zone after ischemic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(2):297-307.
2009: Hao Jiang; Xia Shang; Hongtao Wu; Subhash C Gautam; Shaza Al-Holou; Christina Li; Jarret Kuo; Lijie Zhang; Michael Chopp
Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells.
Journal of experimental therapeutics & oncology 2009;8(1):25-33.
2009: Michael Chopp; Gary K Steinberg; Douglas Kondziolka; Mei Lu; Tonya M Bliss; Yi Li; David C Hess; Cesario V Borlongan
Who's in favor of translational cell therapy for stroke: STEPS forward please?
Cell transplantation 2009;18(7):691-3.
2009: Alexandra Szalad; Mark Katakowski; Xuguang Zheng; Feng Jiang; Michael Chopp
Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia.
Journal of experimental & clinical cancer research : CR 2009;28():129.
2009: Manoranjan Santra; Sutapa Santra; Cindi Roberts; Rui Lan Zhang; Michael Chopp
Doublecortin induces mitotic microtubule catastrophe and inhibits glioma cell invasion.
Journal of neurochemistry 2009;108(1):231-45.
2009: Alex Zacharek; Jieli Chen; Xu Cui; Yuping Yang; Michael Chopp
Simvastatin increases notch signaling activity and promotes arteriogenesis after stroke.
Stroke; a journal of cerebral circulation 2009;40(1):254-60.
2009: Xu Cui; Jieli Chen; Alex Zacharek; Cynthia Roberts; Yuping Yang; Michael Chopp
Nitric oxide donor up-regulation of SDF1/CXCR4 and Ang1/Tie2 promotes neuroblast cell migration after stroke.
Journal of neuroscience research 2009;87(1):86-95.
2008: Asim Mahmood; Anton Goussev; Dunyue Lu; Changsheng Qu; Ye Xiong; Humaira Kazmi; Michael Chopp
Long-lasting benefits after treatment of traumatic brain injury (TBI) in rats with combination therapy of marrow stromal cells (MSCs) and simvastatin.
Journal of neurotrauma 2008;25(12):1441-7.
2008: Asamoah Bosomtwi; Quan Jiang; Guang Liang Ding; Li Zhang; Zheng Gang Zhang; Mei Lu; James R Ewing; Michael Chopp
Quantitative evaluation of microvascular density after stroke in rats using MRI.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(12):1978-87.
2008: Li Hong Shen; Yi Li; Qi Gao; Smita Savant-Bhonsale; Michael Chopp
Down-regulation of neurocan expression in reactive astrocytes promotes axonal regeneration and facilitates the neurorestorative effects of bone marrow stromal cells in the ischemic rat brain.
Glia 2008;56(16):1747-54.
2008: Jing Zhang; Jieli Chen; Yi Li; Xu Cui; Xuguang Zheng; Cynthia Roberts; Mei Lu; Stanton Elias; Michael Chopp
Niaspan treatment improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.
Neurobiology of disease 2008;32(2):273-80.
2008: Hongtao Wu; Dunyue Lu; Hao Jiang; Ye Xiong; Changsheng Qu; Bo Li; Asim Mahmood; Dong Zhou; Michael Chopp
Increase in phosphorylation of Akt and its downstream signaling targets and suppression of apoptosis by simvastatin after traumatic brain injury.
Journal of neurosurgery 2008;109(4):691-8.
2008: Rui Lan Zhang; Chunling Zhang; Li Zhang; Cindi Roberts; Mei Lu; Alissa Kapke; Yisheng Cui; Mitsuyoshi Ninomiya; Toshiaki Nagafuji; Bruce Albala; Zheng Gang Zhang; Michael Chopp
Synergistic effect of an endothelin type A receptor antagonist, S-0139, with rtPA on the neuroprotection after embolic stroke.
Stroke; a journal of cerebral circulation 2008;39(10):2830-6.
2008: Xu Cui; Jieli Chen; Alex Zacharek; Cynthia Roberts; Smita Savant-Bhonsale; Michael Chopp
Treatment of stroke with (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) amino] diazen-1-ium-1, 2-diolate and bone marrow stromal cells upregulates angiopoietin-1/Tie2 and enhances neovascularization.
Neuroscience 2008;156(1):155-64.
2008: Ye Xiong; Asim Mahmood; Dunyue Lu; Changsheng Qu; Humaira Kazmi; Anton Goussev; Zheng Gang Zhang; Constance T Noguchi; Timothy Schallert; Michael Chopp
Histological and functional outcomes after traumatic brain injury in mice null for the erythropoietin receptor in the central nervous system.
Brain research 2008;1230():247-57.
2008: Ye Xiong; Dunyue Lu; Changsheng Qu; Anton Goussev; Timothy Schallert; Asim Mahmood; Michael Chopp
Effects of erythropoietin on reducing brain damage and improving functional outcome after traumatic brain injury in mice.
Journal of neurosurgery 2008;109(3):510-21.
2008: Robert A Knight; Yuxia Han; Tavarekere N Nagaraja; Polly Whitton; Jennifer Ding; Michael Chopp; Donald Seyfried
Temporal MRI assessment of intracerebral hemorrhage in rats.
Stroke; a journal of cerebral circulation 2008;39(9):2596-602.
2008: Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp
Ischemic stroke and neurogenesis in the subventricular zone.
Neuropharmacology 2008;55(3):345-52.
2008: Zhongwu Liu; Yi Li; Xueguo Zhang; Smita Savant-Bhonsale; Michael Chopp
Contralesional axonal remodeling of the corticospinal system in adult rats after stroke and bone marrow stromal cell treatment.
Stroke; a journal of cerebral circulation 2008;39(9):2571-7.
2008: Xian Shuang Liu; Michael Chopp; Manoranjan Santra; Ann Hozeska-Solgot; Rui Lan Zhang; Lei Wang; Hua Teng; Mei Lu; Zheng Gang Zhang
Functional response to SDF1 alpha through over-expression of CXCR4 on adult subventricular zone progenitor cells.
Brain research 2008;1226():18-26.
2008: Brian Silver; Mei Lu; Daniel C Morris; Panayiotis Mitsias; Christopher Lewandowski; Michael Chopp
Blood pressure declines and less favorable outcomes in the NINDS tPA stroke study.
Journal of the neurological sciences 2008;271(1-2):61-7.
2008: Donald Seyfried; Yuxia Han; Dongmei Yang; Jennifer Ding; Smita Savant-Bhonsale; Mohammad S Shukairy; Michael Chopp
Mannitol enhances delivery of marrow stromal cells to the brain after experimental intracerebral hemorrhage.
Brain research 2008;1224():12-9.
2008: Guangliang Ding; Quan Jiang; Lian Li; Li Zhang; Zheng Gang Zhang; Karyn A Ledbetter; Swayamprava Panda; Siamak P N Davarani; Hemanthkumar Athiraman; Qingjiang Li; James R Ewing; Michael Chopp
Magnetic resonance imaging investigation of axonal remodeling and angiogenesis after embolic stroke in sildenafil-treated rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(8):1440-8.
2008: Xuguang Zheng; Feng Jiang; Mark Katakowski; Xuepeng Zhang; Hao Jiang; Zheng Gang Zhang; Michael Chopp
Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion.
Cancer letters 2008;265(2):177-87.
2008: Lei Wang; Michael Chopp; Sara R Gregg; Rui Lan Zhang; Hua Teng; Angela Jiang; Yifan Feng; Zheng Gang Zhang
Neural progenitor cells treated with EPO induce angiogenesis through the production of VEGF.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(7):1361-8.
2008: David S Kwon; Xiaohua Gao; Yong Bo Liu; Deborah S Dulchavsky; Andrew L Danyluk; Mona Bansal; Michael Chopp; Kevin McIntosh; Arbab Ali; Scott Dulchavsky; Subhash C Gautam
Treatment with bone marrow-derived stromal cells accelerates wound healing in diabetic rats.
International wound journal 2008;5(3):453-63.
2008: Jing Zhang; Yi Li; Xuguang Zheng; Qi Gao; Zhongwu Liu; Runjiang Qu; Jade Borneman; Stanton Elias; Michael Chopp
Bone marrow stromal cells protect oligodendrocytes from oxygen-glucose deprivation injury.
Journal of neuroscience research 2008;86(7):1501-10.
2008: Changsheng Qu; Asim Mahmood; Dunyue Lu; Anton Goussev; Ye Xiong; Michael Chopp
Treatment of traumatic brain injury in mice with marrow stromal cells.
Brain research 2008;1208():234-9.
2008: Cesario Borlongan; Michael Chopp; Gary K Steinberg; Tonya M Bliss; Yi Li; Mei Lu; David C Hess; Douglas Kondziolka
Potential of stem/progenitor cells in treating stroke: the missing steps in translating cell therapy from laboratory to clinic.
Regenerative medicine 2008;3(3):249-50.
2008: Guangliang Ding; Quan Jiang; Lian Li; Li Zhang; Zheng Gang Zhang; Karyn A Ledbetter; Lakshman Gollapalli; Swayamprava Panda; Qingjiang Li; James R Ewing; Michael Chopp
Angiogenesis detected after embolic stroke in rat brain using magnetic resonance T2*WI.
Stroke; a journal of cerebral circulation 2008;39(5):1563-8.
2008: Manoranjan Santra; Sutapa Santra; Jing Zhang; Michael Chopp
Ectopic decorin expression up-regulates VEGF expression in mouse cerebral endothelial cells via activation of the transcription factors Sp1, HIF1alpha, and Stat3.
Journal of neurochemistry 2008;105(2):324-37.
2008: Hua Teng; Zheng Gang Zhang; Lei Wang; Rui Lan Zhang; Li Zhang; Dan Morris; Sara R Gregg; Zhenhua Wu; Angela Jiang; Mei Lu; Berislav V Zlokovic; Michael Chopp
Coupling of angiogenesis and neurogenesis in cultured endothelial cells and neural progenitor cells after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(4):764-71.
2008: Qi Gao; Yi Li; Lihong Shen; Jing Zhang; X Zheng; Runjiang Qu; Zhongwu Liu; Michael Chopp
Bone marrow stromal cells reduce ischemia-induced astrocytic activation in vitro.
Neuroscience 2008;152(3):646-55.
2008: Rui Lan Zhang; Zheng Gang Zhang; Cynthia Roberts; Yvonne LeTourneau; Mei Lu; Li Zhang; Ying Wang; Michael Chopp
Lengthening the G(1) phase of neural progenitor cells is concurrent with an increase of symmetric neuron generating division after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(3):602-11.
2008: Michael Chopp; Yi Li; Jing Zhang
Plasticity and remodeling of brain.
Journal of the neurological sciences 2008;265(1-2):97-101.
2008: Hongtao Wu; Dunyue Lu; Hao Jiang; Ye Xiong; Changsheng Qu; Bo Li; Asim Mahmood; Dong Zhou; Michael Chopp
Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury.
Journal of neurotrauma 2008;25(2):130-9.
2008: Mei Lu; Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp
The linkage of neural progenitor cell cycle profiles between embryonic and adult stroke models: Analytical approach II.
Journal of neuroscience methods 2008;167(2):376-83.
2008: Zhongwu Liu; Yi Li; Jing Zhang; Stanton Elias; Michael Chopp
Evaluation of corticospinal axon loss by fluorescent dye tracing in mice with experimental autoimmune encephalomyelitis.
Journal of neuroscience methods 2008;167(2):191-7.
2008: Michael Chopp; Yi Li
Treatment of stroke and intracerebral hemorrhage with cellular and pharmacological restorative therapies.
Acta neurochirurgica. Supplement 2008;105():79-83.
2008: Xin Hong; Feng Jiang; Steven N Kalkanis; Zheng Gang Zhang; Xuepeng Zhang; Xuguang Zheng; Hao Jiang; Tom Mikkelsen; Michael Chopp
Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells.
Journal of experimental & clinical cancer research : CR 2008;27():23.
2008: Feng Jiang; Xuepeng Zhang; Steven N Kalkanis; Zheng Gang Zhang; Hongyan Yang; Mark Katakowski; Xin Hong; Xuguang Zheng; Zhenping Zhu; Michael Chopp
Combination therapy with antiangiogenic treatment and photodynamic therapy for the nude mouse bearing U87 glioblastoma.
Photochemistry and photobiology 2008;84(1):128-37.
2008: Jieli Chen; Alex Zacharek; Ang Li; Xu Cui; Cynthia Roberts; Mei Lu; Michael Chopp
Atorvastatin promotes presenilin-1 expression and Notch1 activity and increases neural progenitor cell proliferation after stroke.
Stroke; a journal of cerebral circulation 2008;39(1):220-6.
2007: Ye Xiong; Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Timothy Schallert; Michael Chopp
Role of gender in outcome after traumatic brain injury and therapeutic effect of erythropoietin in mice.
Brain research 2007;1185():301-12.
2007: Lei Wang; Zheng Gang Zhang; Sara R Gregg; Rui Lan Zhang; Zhongxian Jiao; Yvonne LeTourneau; Xianshuang Liu; Yifan Feng; Jens Gerwien; Lars Torup; Marcel Leist; Constance Tom Noguchi; Zhi-Yong Chen; Michael Chopp
The Sonic hedgehog pathway mediates carbamylated erythropoietin-enhanced proliferation and differentiation of adult neural progenitor cells.
The Journal of biological chemistry 2007;282(44):32462-70.
2007: Li Zhang; Zheng Gang Zhang; Xian Shuang Liu; Ann Hozeska-Solgot; Michael Chopp
The PI3K/Akt pathway mediates the neuroprotective effect of atorvastatin in extending thrombolytic therapy after embolic stroke in the rat.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(11):2470-5.
2007: Xu Cui; Jieli Chen; Alex Zacharek; Yi Li; Cynthia Roberts; Alissa Kapke; Smita Savant-Bhonsale; Michael Chopp
Nitric oxide donor upregulation of stromal cell-derived factor-1/chemokine (CXC motif) receptor 4 enhances bone marrow stromal cell migration into ischemic brain after stroke.
Stem cells (Dayton, Ohio) 2007;25(11):2777-85.
2007: Xuepeng Zhang; Feng Jiang; Steven N Kalkanis; Zheng Gang Zhang; Xin Hong; Hongyan Yang; Michael Chopp
Post-acute response of 9L gliosarcoma to Photofrin-mediated PDT in athymic nude mice.
Lasers in medical science 2007;22(4):253-9.
2007: Hongyan Yang; Michael Chopp; Barbara Weiland; Xuepeng Zhang; Norman Tepley; Feng Jiang; Timothy Schallert
Sensorimotor deficits associated with brain tumor progression and tumor-induced brain plasticity mechanisms.
Experimental neurology 2007;207(2):357-67.
2007: Alex Zacharek; Jieli Chen; Xu Cui; Ang Li; Yi Li; Cynthia Roberts; Yifan Feng; Qi Gao; Michael Chopp
Angiopoietin1/Tie2 and VEGF/Flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(10):1684-91.
2007: Dunyue Lu; Asim Mahmood; Changsheng Qu; Xin Hong; David Kaplan; Michael Chopp
Collagen scaffolds populated with human marrow stromal cells reduce lesion volume and improve functional outcome after traumatic brain injury.
Neurosurgery 2007;61(3):596-602; discussion 602-3.
2007: Hongyan Yang; Michael Chopp; Xuepeng Zhang; Feng Jiang; Zheng Gang Zhang; Steven N Kalkanis; Timothy Schallert
Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models.
Behavioural brain research 2007;182(1):42-50.
2007: Runjiang Qu; Yi Li; Qi Gao; Lihong Shen; Jing Zhang; Zhongwu Liu; Xiaoguang Chen; Michael Chopp
Neurotrophic and growth factor gene expression profiling of mouse bone marrow stromal cells induced by ischemic brain extracts.
Neuropathology : official journal of the Japanese Society of Neuropathology 2007;27(4):355-63.
2007: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Zheng Gang Zhang; Chang Lu; Michael Chopp
Treatment of traumatic brain injury in rats with erythropoietin and carbamylated erythropoietin.
Journal of neurosurgery 2007;107(2):392-7.
2007: Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp
Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain.
Current molecular medicine 2007;7(5):459-62.
2007: Ying Wang; Zheng Gang Zhang; K Rhodes; M Renzi; Rui Lan Zhang; Alissa Kapke; Mei Lu; C Pool; G Heavner; Michael Chopp
Post-ischemic treatment with erythropoietin or carbamylated erythropoietin reduces infarction and improves neurological outcome in a rat model of focal cerebral ischemia.
British journal of pharmacology 2007;151(8):1377-84.
2007: Ana deCarvalho; Xuepeng Zhang; Cynthia Roberts; Feng Jiang; Steven N Kalkanis; Xin Hong; Mei Lu; Michael Chopp
Subclinical photodynamic therapy treatment modifies the brain microenvironment and promotes glioma growth.
Glia 2007;55(10):1053-60.
2007: Xian Shuang Liu; Zheng Gang Zhang; Rui Lan Zhang; Sara R Gregg; Lei Wang; Toh Yier; Michael Chopp
Chemokine ligand 2 (CCL2) induces migration and differentiation of subventricular zone cells after stroke.
Journal of neuroscience research 2007;85(10):2120-5.
2007: Dunyue Lu; Changsheng Qu; Anton Goussev; Hao Jiang; Chang Lu; Timothy Schallert; Asim Mahmood; Jieli Chen; Yi Li; Michael Chopp
Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury.
Journal of neurotrauma 2007;24(7):1132-46.
2007: Jieli Chen; Xu Cui; Alex Zacharek; Hao Jiang; Cynthia Roberts; Chunling Zhang; Mei Lu; Alissa Kapke; Carolyn S Feldkamp; Michael Chopp
Niaspan increases angiogenesis and improves functional recovery after stroke.
Annals of neurology 2007;62(1):49-58.
2007: Li Hong Shen; Yi Li; Jieli Chen; Yisheng Cui; Chunling Zhang; Alissa Kapke; Mei Lu; Smita Savant-Bhonsale; Michael Chopp
One-year follow-up after bone marrow stromal cell treatment in middle-aged female rats with stroke.
Stroke; a journal of cerebral circulation 2007;38(7):2150-6.
2007: Rui Lan Zhang; Zheng Gang Zhang; Ying Wang; Yvonne LeTourneau; Xian Shuang Liu; Xueguo Zhang; Sara R Gregg; Lei Wang; Michael Chopp
Stroke induces ependymal cell transformation into radial glia in the subventricular zone of the adult rodent brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(6):1201-12.
2007: Zhongwu Liu; Yi Li; Runjiang Qu; Lihong Shen; Qi Gao; Xueguo Zhang; Mei Lu; Smita Savant-Bhonsale; Jade Borneman; Michael Chopp
Axonal sprouting into the denervated spinal cord and synaptic and postsynaptic protein expression in the spinal cord after transplantation of bone marrow stromal cell in stroke rats.
Brain research 2007;1149():172-80.
2007: Xian Shuang Liu; Zheng Gang Zhang; Rui Lan Zhang; Sara R Gregg; He Meng; Michael Chopp
Comparison of in vivo and in vitro gene expression profiles in subventricular zone neural progenitor cells from the adult mouse after middle cerebral artery occlusion.
Neuroscience 2007;146(3):1053-61.
2007: Daniel C Morris; Zheng Gang Zhang; Ying Wang; Rui Lan Zhang; Sara R Gregg; Xian Shuang Liu; Michael Chopp
Wnt expression in the adult rat subventricular zone after stroke.
Neuroscience letters 2007;418(2):170-4.
2007: Xueguo Zhang; Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp
Measurement of neuronal activity of individual neurons after stroke in the rat using a microwire electrode array.
Journal of neuroscience methods 2007;162(1-2):91-100.
2007: Xuguang Zheng; Feng Jiang; Mark Katakowski; Steven N Kalkanis; Xin Hong; Xuepeng Zhang; Zheng Gang Zhang; Hongyan Yang; Michael Chopp
Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness.
Cancer science 2007;98(5):674-84.
2007: Mei Lu; Rui Lan Zhang; Zheng Gang Zhang; James Yang; Michael Chopp
Linkage of cell cycle kinetics between embryonic and adult stroke models: an analytical approach.
Journal of neuroscience methods 2007;161(2):323-30.
2007: Mark Katakowski; Jieli Chen; Zheng Gang Zhang; Manoranjan Santra; Ying Wang; Michael Chopp
Stroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(4):669-78.
2007: Rui Lan Zhang; Yvonne LeTourneau; Sara R Gregg; Ying Wang; Yier Toh; Adam M Robin; Zheng Gang Zhang; Michael Chopp
Neuroblast division during migration toward the ischemic striatum: a study of dynamic migratory and proliferative characteristics of neuroblasts from the subventricular zone.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(12):3157-62.
2007: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Michael Chopp
Treatment of traumatic brain injury with a combination therapy of marrow stromal cells and atorvastatin in rats.
Neurosurgery 2007;60(3):546-53; discussion 553-4.
2007: Xian Shuang Liu; Zheng Gang Zhang; Rui Lan Zhang; Sara R Gregg; Daniel C Morris; Ying Wang; Michael Chopp
Stroke induces gene profile changes associated with neurogenesis and angiogenesis in adult subventricular zone progenitor cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(3):564-74.
2007: Lian Li; Quan Jiang; Li Zhang; Guangliang Ding; Zheng Gang Zhang; Qingjiang Li; James R Ewing; Mei Lu; Swayamprava Panda; Karyn A Ledbetter; Polly A Whitton; Michael Chopp
Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke.
Brain research 2007;1132(1):185-92.
2007: Michael Chopp; Zheng Gang Zhang; Quan Jiang
Neurogenesis, angiogenesis, and MRI indices of functional recovery from stroke.
Stroke; a journal of cerebral circulation 2007;38(2 Suppl):827-31.
2007: Xin Hong; Feng Jiang; Steven N Kalkanis; Zheng Gang Zhang; Xuepeng Zhang; Xuguang Zheng; Tom Mikkelsen; Hao Jiang; Michael Chopp
Decrease of endogenous vascular endothelial growth factor may not affect glioma cell proliferation and invasion.
Journal of experimental therapeutics & oncology 2007;6(3):219-29.
2007: Hamid Soltanian-Zadeh; Hassan Bagher-Ebadian; James R Ewing; Panayiotis Mitsias; Alissa Kapke; Mei Lu; Quan Jiang; Suresh C Patel; Michael Chopp
Multiparametric iterative self-organizing data analysis of ischemic lesions using pre- or post-Gd T1 MRI.
Cerebrovascular diseases (Basel, Switzerland) 2007;23(2-3):91-102.
2007: Li Hong Shen; Yi Li; Jieli Chen; Alex Zacharek; Qi Gao; Alissa Kapke; Mei Lu; Kimberly Raginski; P Vanguri; Alan Smith; Michael Chopp
Therapeutic benefit of bone marrow stromal cells administered 1 month after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):6-13.
2006: Manoranjan Santra; Xuepeng Zhang; Sutapa Santra; Feng Jiang; Michael Chopp
Ectopic doublecortin gene expression suppresses the malignant phenotype in glioblastoma cells.
Cancer research 2006;66(24):11726-35.
2006: Yongbo Liu; Deborah S Dulchavsky; Xiaohua Gao; David Kwon; Michael Chopp; Scott Dulchavsky; Subhash C Gautam
Wound repair by bone marrow stromal cells through growth factor production.
The Journal of surgical research 2006;136(2):336-41.
2006: Li Zhang; Zheng Gang Zhang; Rui Lan Zhang; Yisheng Cui; Margot C LaPointe; Brian Silver; Michael Chopp
Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke.
Brain research 2006;1118(1):192-8.
2006: Tong Cheng; Anthony L Petraglia; Zhang Li; Meenakshisundaram Thiyagarajan; Zhihui Zhong; Zhenhua Wu; Dong Liu; Sanjay B Maggirwar; Rashid Deane; José A Fernández; Barbra LaRue; John H Griffin; Michael Chopp; Berislav V Zlokovic
Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.
Nature medicine 2006;12(11):1278-85.
2006: Xuepeng Zhang; Feng Jiang; Steven N Kalkanis; Hongyan Yang; Zheng Gang Zhang; Mark Katakowski; Xin Hong; Xuguang Zheng; Michael Chopp
Combination of surgical resection and photodynamic therapy of 9L gliosarcoma in the nude rat.
Photochemistry and photobiology 2006;82(6):1704-11.
2006: Lian Li; Quan Jiang; Li Zhang; Guangliang Ding; Lei Wang; Rui Lan Zhang; Zheng Gang Zhang; Qingjiang Li; James R Ewing; Alissa Kapke; Mei Lu; Michael Chopp
Ischemic cerebral tissue response to subventricular zone cell transplantation measured by iterative self-organizing data analysis technique algorithm.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(11):1366-77.
2006: Manoranjan Santra; X Shuang Liu; S Santra; Jing Zhang; Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp
Ectopic expression of doublecortin protects adult rat progenitor cells and human glioma cells from severe oxygen and glucose deprivation.
Neuroscience 2006;142(3):739-52.
2006: Guangliang Ding; Quan Jiang; Lian Li; Li Zhang; Zheng Gang Zhang; Karyn A Ledbetter; James R Ewing; Qingjiang Li; Michael Chopp
Detection of BBB disruption and hemorrhage by Gd-DTPA enhanced MRI after embolic stroke in rat.
Brain research 2006;1114(1):195-203.
2006: Jieli Chen; Michael Chopp
Neurorestorative treatment of stroke: cell and pharmacological approaches.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2006;3(4):466-73.
2006: Michael Chopp; Michael Weinrich
Translational issues in neurorehabilitation.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2006;3(4):418-9.
2006: Amir Oron; Uri Oron; Jieli Chen; Anda Eilam; Chunling Zhang; Menachem Sadeh; Yair Lampl; Jackson Streeter; Luis Detaboada; Michael Chopp
Low-level laser therapy applied transcranially to rats after induction of stroke significantly reduces long-term neurological deficits.
Stroke; a journal of cerebral circulation 2006;37(10):2620-4.
2006: Manoranjan Santra; Mark Katakowski; Rui Lan Zhang; Zheng Gang Zhang; He Meng; Feng Jiang; Michael Chopp
Protection of adult mouse progenitor cells and human glioma cells by de novo decorin expression in an oxygen- and glucose-deprived cell culture model system.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(10):1311-22.
2006: Hongyan Yang; Xuepeng Zhang; Michael Chopp; Feng Jiang; Timothy Schallert
Local fluorouracil chemotherapy interferes with neural and behavioral recovery after brain tumor-like mass compression.
Behavioural brain research 2006;172(1):80-9.
2006: Quan Jiang; Zheng Gang Zhang; Guang Liang Ding; Brian Silver; Li Zhang; He Meng; Mei Lu; Siamak Pourabdillah-Nejed-D; Lei Wang; Smita Savant-Bhonsale; Lian Li; Hassan Bagher-Ebadian; Jiani Hu; Arbab Ali; P Vanguri; James R Ewing; Karyn A Ledbetter; Michael Chopp
MRI detects white matter reorganization after neural progenitor cell treatment of stroke.
NeuroImage 2006;32(3):1080-9.
2006: Jieli Chen; Alex Zacharek; A Li; C Zhang; J Ding; Cynthia Roberts; Mei Lu; Alissa Kapke; Michael Chopp
Vascular endothelial growth factor mediates atorvastatin-induced mammalian achaete-scute homologue-1 gene expression and neuronal differentiation after stroke in retired breeder rats.
Neuroscience 2006;141(2):737-44.
2006: C Zhang; Yi Li; Jieli Chen; Qi Gao; Alex Zacharek; Alissa Kapke; Michael Chopp
Bone marrow stromal cells upregulate expression of bone morphogenetic proteins 2 and 4, gap junction protein connexin-43 and synaptophysin after stroke in rats.
Neuroscience 2006;141(2):687-95.
2006: Zhongxian Jiao; Zheng Gang Zhang; Thomas Hornyak; Ann Hozeska; Rui Lan Zhang; Ying Wang; Lei Wang; Cynthia Roberts; Faith M Strickland; Michael Chopp
Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation.
Developmental biology 2006;296(2):396-408.
2006: Jing Zhang; Yi Li; Mei Lu; Yisheng Cui; Jieli Chen; Lori Noffsinger; Stanton Elias; Michael Chopp
Bone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis mice.
Journal of neuroscience research 2006;84(3):587-95.
2006: Alex Zacharek; Jieli Chen; Chunling Zhang; Xu Cui; Cynthia Roberts; Hao Jiang; Hua Teng; Michael Chopp
Nitric oxide regulates Angiopoietin1/Tie2 expression after stroke.
Neuroscience letters 2006;404(1-2):28-32.
2006: Guangliang Ding; Quan Jiang; Lian Li; Li Zhang; Zheng Gang Zhang; Swayamprava Panda; James R Ewing; Michael Chopp
MRI of combination treatment of embolic stroke in rat with rtPA and atorvastatin.
Journal of the neurological sciences 2006;246(1-2):139-47.
2006: Kellie McFarlin; Xiaohua Gao; Yong Bo Liu; Deborah S Dulchavsky; David Kwon; Arbab Ali; Mona Bansal; Joan C. Dunbar; Michael Chopp; Scott Dulchavsky; Subhash C Gautam
Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(4):471-8.
2006: Hongyan Yang; Michael Chopp; Feng Jiang; Xuepeng Zhang; Timothy Schallert
Interruption of functional recovery by the NMDA glutamate antagonist MK801 after compression of the sensorimotor cortex: implications for treatment of tumors or other mass-related brain injuries.
Experimental neurology 2006;200(1):262-6.
2006: Jieli Chen; Alex Zacharek; Yi Li; A Li; Lei Wang; Mark Katakowski; Cynthia Roberts; Mei Lu; Michael Chopp
N-cadherin mediates nitric oxide-induced neurogenesis in young and retired breeder neurospheres.
Neuroscience 2006;140(2):377-88.
2006: Hongqi Xin; Yi Li; Xiaoguang Chen; Michael Chopp
Bone marrow stromal cells induce BMP2/4 production in oxygen-glucose-deprived astrocytes, which promotes an astrocytic phenotype in adult subventricular progenitor cells.
Journal of neuroscience research 2006;83(8):1485-93.
2006: Rui Lan Zhang; Zheng Gang Zhang; Mei Lu; Ying Wang; James Yang; Michael Chopp
Reduction of the cell cycle length by decreasing G1 phase and cell cycle reentry expand neuronal progenitor cells in the subventricular zone of adult rat after stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(6):857-63.
2006: Xian Shuang Liu; Zheng Gang Zhang; Li Zhang; Daniel C Morris; Alissa Kapke; Mei Lu; Michael Chopp
Atorvastatin downregulates tissue plasminogen activator-aggravated genes mediating coagulation and vascular permeability in single cerebral endothelial cells captured by laser microdissection.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(6):787-96.
2006: Lei Wang; Zheng Gang Zhang; Rui Lan Zhang; Sara R Gregg; Ann Hozeska-Solgot; Yvonne LeTourneau; Ying Wang; Michael Chopp
Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(22):5996-6003.
2006: Rui Lan Zhang; Zheng Gang Zhang; Li Zhang; Ying Wang; Chunling Zhang; Michael Chopp
Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia.
Journal of neuroscience research 2006;83(7):1213-9.
2006: Xin Hong; Feng Jiang; Steven N Kalkanis; Zheng Gang Zhang; Xue-Peng Zhang; Ana deCarvalho; Mark Katakowski; kevin bobbitt; Tom Mikkelsen; Michael Chopp
SDF-1 and CXCR4 are up-regulated by VEGF and contribute to glioma cell invasion.
Cancer letters 2006;236(1):39-45.
2006: Brian Silver; Kavita M Grover; Ximena Arcila; Panayiotis Mitsias; Susan Bowyer; Michael Chopp
Recovery in a patient with locked-in syndrome.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2006;33(2):246-9.
2006: Hongyan Yang; Marnie Preston; Michael Chopp; Feng Jiang; Xuepeng Zhang; Timothy Schallert
Mass-related traumatic tissue displacement and behavior: a screen for treatments that reduce [corrected] harm to bystander cells and recovery of function.
Journal of neurotrauma 2006;23(5):721-32.
2006: Guangliang Ding; Quan Jiang; Lian Li; Li Zhang; Zheng Gang Zhang; Hamid Soltanian-Zadeh; Qingjiang Li; Polly A Whitton; James R Ewing; Michael Chopp
Characterization of cerebral tissue by MRI map ISODATA in embolic stroke in rat.
Brain research 2006;1084(1):202-9.
2006: Yi Li; Kevin McIntosh; Jieli Chen; Chunling Zhang; Qi Gao; Jade Borneman; Kimberly Raginski; James Mitchell; Lihong Shen; Jing Zhang; Dunyue Lu; Michael Chopp
Allogeneic bone marrow stromal cells promote glial-axonal remodeling without immunologic sensitization after stroke in rats.
Experimental neurology 2006;198(2):313-25.
2006: Lei Wang; Zheng Gang Zhang; Rui Lan Zhang; Zhongxian Jiao; Ying Wang; S Pourabdollah-Nejad D; Yvonne LeTourneau; Sara R Gregg; Michael Chopp
Neurogenin 1 mediates erythropoietin enhanced differentiation of adult neural progenitor cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(4):556-64.
2006: Donald Seyfried; Jennifer Ding; Yuxia Han; Yi Li; Jieli Chen; Michael Chopp
Effects of intravenous administration of human bone marrow stromal cells after intracerebral hemorrhage in rats.
Journal of neurosurgery 2006;104(2):313-8.
2006: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Michael Chopp
Long-term recovery after bone marrow stromal cell treatment of traumatic brain injury in rats.
Journal of neurosurgery 2006;104(2):272-7.
2006: He Meng; Zheng Gang Zhang; Rui Lan Zhang; Xiansuang Liu; Lei Wang; Adam M Robin; Michael Chopp
Biphasic effects of exogenous VEGF on VEGF expression of adult neural progenitors.
Neuroscience letters 2006;393(2-3):97-101.
2006: Michael Chopp; Yi Li
Transplantation of bone marrow stromal cells for treatment of central nervous system diseases.
Advances in experimental medicine and biology 2006;585():49-64.
2006: Li Zhang; Zheng Gang Zhang; Xianshuang Liu; Ann Hozeska; Nancy Stagliano; William Riordan; Mei Lu; Michael Chopp
Treatment of embolic stroke in rats with bortezomib and recombinant human tissue plasminogen activator.
Thrombosis and haemostasis 2006;95(1):166-73.
2006: Li Hong Shen; Yi Li; Jieli Chen; Jing Zhang; P Vanguri; Jade Borneman; Michael Chopp
Intracarotid transplantation of bone marrow stromal cells increases axon-myelin remodeling after stroke.
Neuroscience 2006;137(2):393-9.
2006: Adam M Robin; Zheng Gang Zhang; Lei Wang; Rui Lan Zhang; Mark Katakowski; Li Zhang; Ying Wang; Chunling Zhang; Michael Chopp
Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(1):125-34.
2005: Zheng Gang Zhang; Li Zhang; Guangliang Ding; Quan Jiang; Rui Lan Zhang; Xueguo Zhang; Wen-Biao Gan; Michael Chopp
A model of mini-embolic stroke offers measurements of the neurovascular unit response in the living mouse.
Stroke; a journal of cerebral circulation 2005;36(12):2701-4.
2005: Li Zhang; Zheng Gang Zhang; Guang Liang Ding; Quan Jiang; Xianshuang Liu; He Meng; Ann Hozeska; Chunling Zhang; Lian Li; Dan Morris; Rui Lan Zhang; Mei Lu; Michael Chopp
Multitargeted effects of statin-enhanced thrombolytic therapy for stroke with recombinant human tissue-type plasminogen activator in the rat.
Circulation 2005;112(22):3486-94.
2005: Quan Jiang; Zheng Gang Zhang; Guang Liang Ding; Li Zhang; James R Ewing; Lei Wang; Rui Lan Zhang; Lian Li; Mei Lu; He Meng; Arbab Ali; Jiani Hu; Qing Jiang Li; Siamak Pourabdollah Nejad D; Hemanthkumar Athiraman; Michael Chopp
Investigation of neural progenitor cell induced angiogenesis after embolic stroke in rat using MRI.
NeuroImage 2005;28(3):698-707.
2005: Asim Mahmood; Dunyue Lu; Changsheng Qu; Anton Goussev; Michael Chopp
Human marrow stromal cell treatment provides long-lasting benefit after traumatic brain injury in rats.
Neurosurgery 2005;57(5):1026-31; discussion 1026-31.
2005: Hamid Soltanian-Zadeh; Ali Shahrokni; Mohammad-Mehdi Khalighi; Zheng Gang Zhang; Reza A Zoroofi; Mahnaz Maddah; Michael Chopp
3-D quantification and visualization of vascular structures from confocal microscopic images using skeletonization and voxel-coding.
Computers in biology and medicine 2005;35(9):791-813.
2005: Changsheng Qu; Dunyue Lu; Anton Goussev; Timothy Schallert; Asim Mahmood; Michael Chopp
Effect of atorvastatin on spatial memory, neuronal survival, and vascular density in female rats after traumatic brain injury.
Journal of neurosurgery 2005;103(4):695-701.
2005: Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp
Neurogenesis in the adult ischemic brain: generation, migration, survival, and restorative therapy.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2005;11(5):408-16.
2005: Mark Katakowski; Zheng Gang Zhang; Ana deCarvalho; Michael Chopp
EphB2 induces proliferation and promotes a neuronal fate in adult subventricular neural precursor cells.
Neuroscience letters 2005;385(3):204-9.
2005: Dunyue Lu; Asim Mahmood; Changsheng Qu; Anton Goussev; Timothy Schallert; Michael Chopp
Erythropoietin enhances neurogenesis and restores spatial memory in rats after traumatic brain injury.
Journal of neurotrauma 2005;22(9):1011-7.
2005: Berislav V Zlokovic; Chunling Zhang; Dong Liu; Jose Fernandez; John H Griffin; Michael Chopp
Functional recovery after embolic stroke in rodents by activated protein C.
Annals of neurology 2005;58(3):474-7.
2005: Xuepeng Zhang; Feng Jiang; Zheng Gang Zhang; Steven N Kalkanis; Xin Hong; Ana deCarvalho; Jieli Chen; Hongyan Yang; Adam M Robin; Michael Chopp
Low-dose photodynamic therapy increases endothelial cell proliferation and VEGF expression in nude mice brain.
Lasers in medical science 2005;20(2):74-9.
2005: Jing Zhang; Yi Li; Jieli Chen; Yisheng Cui; Mei Lu; Stanton Elias; James B Mitchell; Lora Hammill; P Vanguri; Michael Chopp
Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice.
Experimental neurology 2005;195(1):16-26.
2005: Lei Wang; Zheng Gang Zhang; Rui Lan Zhang; Michael Chopp
Activation of the PI3-K/Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(9):1150-8.
2005: Panayiotis Mitsias; Mei Lu; Brian Silver; D Morris; James R Ewing; Sheila Daley; Christopher Lewandowski; Angelos M Katramados; Nikolaos I.H. Papamitsakis; Hassan B Ebadian; Qingming Zhao; Hamid Soltanian-Zadeh; David Hearshen; Suresh C Patel; Michael Chopp
MRI-guided, open trial of abciximab for ischemic stroke within a 3- to 24-hour window.
Neurology 2005;65(4):612-5.
2005: Feng Jiang; Zheng Gang Zhang; Steven N Kalkanis; Mark Katakowksi; Adam M Robin; Xuepeng Zhang; Ari Gotlib; Isaac Chelst; Tom Mikkelsen; Michael Chopp
A quantitative model of tumor-induced angiogenesis in the nude mouse.
Neurosurgery 2005;57(2):320-4.
2005: Mei Lu; Michael Krams; Li Zhang; Zheng Gang Zhang; Michael Chopp
Assessing combination treatments in acute stroke: preclinical experiences.
Behavioural brain research 2005;162(2):165-72.
2005: Lian Li; Quan Jiang; Guangliang Ding; Li Zhang; Zheng Gang Zhang; James R Ewing; Robert A Knight; Alissa Kapke; Hamid Soltanian-Zadeh; Michael Chopp
Map-ISODATA demarcates regional response to combination rt-PA and 7E3 F(ab')2 treatment of embolic stroke in the rat.
Journal of magnetic resonance imaging : JMRI 2005;21(6):726-34.
2005: Guangliang Ding; Vijaya Nagesh; Quan Jiang; Li Zhang; Zheng Gang Zhang; Lian Li; Robert A Knight; Qingjiang Li; James R Ewing; Michael Chopp
Early prediction of gross hemorrhagic transformation by noncontrast agent MRI cluster analysis after embolic stroke in rat.
Stroke; a journal of cerebral circulation 2005;36(6):1247-52.
2005: Mei Lu; Panayiotis Mitsias; James R Ewing; Hamid Soltanian-Zadeh; Hassan Bagher-Ebadian; Qingming Zhao; Nancy Oja-Tebbe; Suresh C Patel; Michael Chopp
Predicting final infarct size using acute and subacute multiparametric MRI measurements in patients with ischemic stroke.
Journal of magnetic resonance imaging : JMRI 2005;21(5):495-502.
2005: Quan Jiang; James R Ewing; Guang Liang Ding; Li Zhang; Zheng Gang Zhang; Lian Li; Polly A Whitton; Mei Lu; Jiani Hu; Qing Jiang Li; Robert A Knight; Michael Chopp
Quantitative evaluation of BBB permeability after embolic stroke in rat using MRI.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(5):583-92.
2005: Li Zhang; Rui Lan Zhang; Ying Wang; Chunling Zhang; Zheng Gang Zhang; He Meng; Michael Chopp
Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor.
Stroke; a journal of cerebral circulation 2005;36(4):847-52.
2005: Jieli Chen; Alex Zacharek; Chunling Zhang; Hao Jiang; Yi Li; Cynthia Roberts; Mei Lu; Alissa Kapke; Michael Chopp
Endothelial nitric oxide synthase regulates brain-derived neurotrophic factor expression and neurogenesis after stroke in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(9):2366-75.
2005: Jing Zhang; Yi Li; Yisheng Cui; Jieli Chen; Mei Lu; Stanton Elias; Michael Chopp
Erythropoietin treatment improves neurological functional recovery in EAE mice.
Brain research 2005;1034(1-2):34-9.
2005: Jieli Chen; Chunling Zhang; Hao Jiang; Yi Li; Lijie Zhang; Adam M Robin; Mark Katakowski; Mei Lu; Michael Chopp
Atorvastatin induction of VEGF and BDNF promotes brain plasticity after stroke in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(2):281-90.
2005: Yi Li; Jieli Chen; Chun Ling Zhang; Lei Wang; Dunyue Lu; Mark Katakowski; Qi Gao; Li Hong Shen; Jing Zhang; Mei Lu; Michael Chopp
Gliosis and brain remodeling after treatment of stroke in rats with marrow stromal cells.
Glia 2005;49(3):407-17.
2005: Qi Gao; Yi Li; Michael Chopp
Bone marrow stromal cells increase astrocyte survival via upregulation of phosphoinositide 3-kinase/threonine protein kinase and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways and stimulate astrocyte trophic factor gene expression after anaerobic insult.
Neuroscience 2005;136(1):123-34.
2005: Qi Gao; Mark Katakowski; Xiaoguang Chen; Yi Li; Michael Chopp
Human marrow stromal cells enhance connexin43 gap junction intercellular communication in cultured astrocytes.
Cell transplantation 2005;14(2-3):109-17.
2005: Guangliang Ding; Quan Jiang; Li Zhang; Zheng Gang Zhang; Lian Li; Robert A Knight; James R Ewing; Ying Wang; Michael Chopp
Analysis of combined treatment of embolic stroke in rat with r-tPA and a GPIIb/IIIa inhibitor.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(1):87-97.
2004: Jing Zhang; Yi Li; Jieli Chen; Maozhou Yang; Mark Katakowski; Mei Lu; Michael Chopp
Expression of insulin-like growth factor 1 and receptor in ischemic rats treated with human marrow stromal cells.
Brain research 2004;1030(1):19-27.
2004: Dunyue Lu; Asim Mahmood; Anton Goussev; Changsheng Qu; Zheng Gang Zhang; Michael Chopp
Delayed thrombosis after traumatic brain injury in rats.
Journal of neurotrauma 2004;21(12):1756-66.
2004: Li Zhang; Zheng Gang Zhang; Chunling Zhang; Rui Lan Zhang; Michael Chopp
Intravenous administration of a GPIIb/IIIa receptor antagonist extends the therapeutic window of intra-arterial tenecteplase-tissue plasminogen activator in a rat stroke model.
Stroke; a journal of cerebral circulation 2004;35(12):2890-5.
2004: Dunyue Lu; Asim Mahmood; Changsheng Qu; Anton Goussev; Mei Lu; Michael Chopp
Atorvastatin reduction of intracranial hematoma volume in rats subjected to controlled cortical impact.
Journal of neurosurgery 2004;101(5):822-5.
2004: Dunyue Lu; Asim Mahmood; Anton Goussev; Timothy Schallert; Changsheng Qu; Zheng Gang Zhang; Yi Li; Mei Lu; Michael Chopp
Atorvastatin reduction of intravascular thrombosis, increase in cerebral microvascular patency and integrity, and enhancement of spatial learning in rats subjected to traumatic brain injury.
Journal of neurosurgery 2004;101(5):813-21.
2004: Asim Mahmood; Dunyue Lu; Michael Chopp
Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain.
Neurosurgery 2004;55(5):1185-93.
2004: Panayiotis Mitsias; James R Ewing; Mei Lu; Mohammad-Mehdi Khalighi; Mamatha Pasnoor; Hassan B Ebadian; Qingming Zhao; Sunitha Santhakumar; Michael A Jacobs; Nikolaos I.H. Papamitsakis; Hamid Soltanian-Zadeh; David Hearshen; Suresh C Patel; Michael Chopp
Multiparametric iterative self-organizing MR imaging data analysis technique for assessment of tissue viability in acute cerebral ischemia.
AJNR. American journal of neuroradiology 2004;25(9):1499-508.
2004: Mei Lu; Zheng Gang Zhang; Michael Chopp
Analysis of cerebral microvascular architecture--application to cortical and subcortical vessels in rat brain.
Journal of neuroscience methods 2004;138(1-2):81-7.
2004: Quan Jiang; Zheng Gang Zhang; Li Zhang; Guang Liang Ding; Lian Li; James R Ewing; Mei Lu; Polly A Whitton; Jiani Hu; Qing Jiang Li; Rui Lan Zhang; Michael Chopp
MRI evaluation of treatment of embolic stroke in rat with intra-arterial and intravenous rt-PA.
Journal of the neurological sciences 2004;224(1-2):57-67.
2004: Zheng Gang Zhang; Quan Jiang; Feng Jiang; Gaungliang Ding; Rui Lan Zhang; Lei Wang; Li Zhang; Adam M Robin; Mark Katakowski; Michael Chopp
In vivo magnetic resonance imaging tracks adult neural progenitor cell targeting of brain tumor.
NeuroImage 2004;23(1):281-7.
2004: Guangliang Ding; Quan Jiang; Li Zhang; Zheng Gang Zhang; Robert A Knight; Hamid Soltanian-Zadeh; Mei Lu; James R Ewing; Qingjiang Li; Polly A Whitton; Michael Chopp
Multiparametric ISODATA analysis of embolic stroke and rt-PA intervention in rat.
Journal of the neurological sciences 2004;223(2):135-43.
2004: Rui Lan Zhang; Zheng Gang Zhang; Wayne Tsang; Lei Wang; Michael Chopp
Down-regulation of p27kip1 increases proliferation of progenitor cells in adult rats.
Neuroreport 2004;15(11):1797-800.
2004: Donald Seyfried; Yuxia Han; Dunyue Lu; Jieli Chen; Ali Bydon; Michael Chopp
Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats.
Journal of neurosurgery 2004;101(1):104-7.
2004: Lei Wang; Zheng Gang Zhang; Ying Wang; Rui Lan Zhang; Michael Chopp
Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats.
Stroke; a journal of cerebral circulation 2004;35(7):1732-7.
2004: Rui Lan Zhang; Zheng Gang Zhang; Chunling Zhang; Li Zhang; Adam M Robin; Ying Wang; Mei Lu; Michael Chopp
Stroke transiently increases subventricular zone cell division from asymmetric to symmetric and increases neuronal differentiation in the adult rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(25):5810-5.
2004: Lei Wang; Zheng Gang Zhang; Rui Lan Zhang; Mikehl S Hafner; Henry K Wong; ZhongXian Jiao; Michael Chopp
Erythropoietin up-regulates SOCS2 in neuronal progenitor cells derived from SVZ of adult rat.
Neuroreport 2004;15(8):1225-9.
2004: Feng Jiang; Zheng Gang Zhang; Mark Katakowski; Adam M Robin; Michelle Faber; Fan Zhang; Michael Chopp
Angiogenesis induced by photodynamic therapy in normal rat brains.
Photochemistry and photobiology 2004;79(6):494-8.
2004: Jieli Chen; Yi Li; Rui Lan Zhang; Mark Katakowski; Subhash C Gautam; Yongxian Xu; Mei Lu; Zheng Gang Zhang; Michael Chopp
Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis.
Brain research 2004;1005(1-2):21-8.
2004: Rui Lan Zhang; Zheng Gang Zhang; Lei Wang; Ying Wang; Anton Gousev; Li Zhang; Khang-Loon Ho; Cindi M Morshead; Michael Chopp
Activated neural stem cells contribute to stroke-induced neurogenesis and neuroblast migration toward the infarct boundary in adult rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(4):441-8.
2004: Panayiotis Mitsias; Mei Lu; Dan Morris; Brian Silver; Christopher Lewandowski; Nikolaos I.H. Papamitsakis; Mohammed M Khaligi; Hassan B Ebadian; Qingming Zhao; Hamid Soltanian-Zadeh; Sheila Daley; David Hearshen; James R Ewing; Suresh C Patel; Michael Chopp
Treatment of acute supratentorial ischemic stroke with abciximab is safe and may result in early neurological improvement. A preliminary report.
Cerebrovascular diseases (Basel, Switzerland) 2004;18(3):249-50.
2004: Asim Mahmood; Dunyue Lu; Michael Chopp
Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury.
Journal of neurotrauma 2004;21(1):33-9.
2004: Dunyue Lu; Anton Goussev; Jieli Chen; Paul Pannu; Yi Li; Asim Mahmood; Michael Chopp
Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury.
Journal of neurotrauma 2004;21(1):21-32.
2003: Mark Katakowski; Zheng Gang Zhang; Jieli Chen; Rui Lan Zhang; Ying Wang; Hao Jiang; Lijie Zhang; Adam M Robin; Yi Li; Michael Chopp
Phosphoinositide 3-kinase promotes adult subventricular neuroblast migration after stroke.
Journal of neuroscience research 2003;74(4):494-501.
2003: Mei Lu; Jieli Chen; Dunyue Lu; Li Yi; Asim Mahmood; Michael Chopp
Global test statistics for treatment effect of stroke and traumatic brain injury in rats with administration of bone marrow stromal cells.
Journal of neuroscience methods 2003;128(1-2):183-90.
2003: Jieli Chen; Yi Li; Mark Katakowski; Xiaoguang Chen; Lei Wang; Dunyue Lu; Mei Lu; Subhash C Gautam; Michael Chopp
Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat.
Journal of neuroscience research 2003;73(6):778-86.
2003: Asim Mahmood; Dunyue Lu; Mei Lu; Michael Chopp
Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells.
Neurosurgery 2003;53(3):697-702; discussion 702-3.
2003: Dunyue Lu; Asim Mahmood; Michael Chopp
Biologic transplantation and neurotrophin-induced neuroplasticity after traumatic brain injury.
The Journal of head trauma rehabilitation 2003;18(4):357-76.
2003: Li Zhang; Zheng Gang Zhang; Rui Lan Zhang; Mei Lu; Michael Krams; Michael Chopp
Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke.
Stroke; a journal of cerebral circulation 2003;34(7):1790-5.
2003: Li Zhang; Zheng Gang Zhang; Rui Lan Zhang; Daniel Morris; Mei Lu; Barry S Coller; Michael Chopp
Adjuvant treatment with a glycoprotein IIb/IIIa receptor inhibitor increases the therapeutic window for low-dose tissue plasminogen activator administration in a rat model of embolic stroke.
Circulation 2003;107(22):2837-43.
2003: Jieli Chen; Zheng Gang Zhang; Yi Li; Ying Wang; Lei Wang; Hao Jiang; Chenling Zhang; Mei Lu; Mark Katakowski; Carolyn S Feldkamp; Michael Chopp
Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke.
Annals of neurology 2003;53(6):743-51.
2003: Daniel C Morris; Thomas Yeich; Mohammad-Mehdi Khalighi; Hamid Soltanian-Zadeh; Zheng Gang Zhang; Michael Chopp
Microvascular structure after embolic focal cerebral ischemia in the rat.
Brain research 2003;972(1-2):31-7.
2003: Jieli Chen; Zheng Gang Zhang; Yi Li; Lei Wang; Yong Xian Xu; Subhash C Gautam; Mei Lu; Zhenping Zhu; Michael Chopp
Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats.
Circulation research 2003;92(6):692-9.
2003: Hamid Soltanian-Zadeh; Mamatha Pasnoor; Rabih Hammoud; Michael A Jacobs; Suresh C Patel; Panayiotis Mitsias; Robert A Knight; Zhang G Zheng; Mei Lu; Michael Chopp
MRI tissue characterization of experimental cerebral ischemia in rat.
Journal of magnetic resonance imaging : JMRI 2003;17(4):398-409.
2003: Rui Lan Zhang; Lei Wang; Li Zhang; Jieli Chen; Zhenping Zhu; Zheng Gang Zhang; Michael Chopp
Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat.
Circulation research 2003;92(3):308-13.
2003: Richard L Harvey; Michael Chopp
The therapeutic effects of cellular therapy for functional recovery after brain injury.
Physical medicine and rehabilitation clinics of North America 2003;14(1 Suppl):S143-51.
2003: Xinkang Wang; Lin Xu; Hugh Wang; Reinhard Grzanna; Yutian Zhan; Robert M Knabb; Joseph M Luettgen; Tracy A Bozarth; Robert Anthony Galemmo; Pancras C Wong; Roberta Bernard; Hugo Vargas; Michael Chopp; Steven M Friedman; Giora Z Feuerstein
Inhibition of factor Xa reduces ischemic brain damage after thromboembolic stroke in rats.
Stroke; a journal of cerebral circulation 2003;34(2):468-74.
2003: Zheng Gang Zhang; Quan Jiang; Rui Lan Zhang; Li Zhang; Lei Wang; Lijei Zhang; Polly Arniego; Khang-Loon Ho; Michael Chopp
Magnetic resonance imaging and neurosphere therapy of stroke in rat.
Annals of neurology 2003;53(2):259-63.
2003: Feng Jiang; Adam M Robin; Mark Katakowski; L Tong; M Espiritu; G Singh; Michael Chopp
Photodynamic therapy with photofrin in combination with Buthionine Sulfoximine (BSO) of human glioma in the nude rat.
Lasers in medical science 2003;18(3):128-33.
2003: Rui Lan Zhang; L Zhang; Zheng Gang Zhang; D Morris; Quan Jiang; Lei Wang; Li Zhang; Michael Chopp
Migration and differentiation of adult rat subventricular zone progenitor cells transplanted into the adult rat striatum.
Neuroscience 2003;116(2):373-82.
2002: Xiaoguang Chen; Yi Li; Lei Wang; Mark Katakowski; Lijie Zhang; Jieli Chen; Yongxian Xu; Subhash C Gautam; Michael Chopp
Ischemic rat brain extracts induce human marrow stromal cell growth factor production.
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(4):275-9.
2002: Asim Mahmood; Dunyue Lu; Lei Wang; Michael Chopp
Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury.
Journal of neurotrauma 2002;19(12):1609-17.
2002: Panayiotis Mitsias; Michael A Jacobs; Rabih Hammoud; Mamatha Pasnoor; Sunitha Santhakumar; Nikolaos I.H. Papamitsakis; Hamid Soltanian-Zadeh; Mei Lu; Michael Chopp; Suresh C Patel
Multiparametric MRI ISODATA ischemic lesion analysis: correlation with the clinical neurological deficit and single-parameter MRI techniques.
Stroke; a journal of cerebral circulation 2002;33(12):2839-44.
2002: Rui Lan Zhang; Ying Wang; Li Zhang; Zheng Gang Zhang; Wayne Tsang; Mei Lu; Lijie Zhang; Michael Chopp
Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats.
Stroke; a journal of cerebral circulation 2002;33(11):2675-80.
2002: Dunyue Lu; Yi Li; Asim Mahmood; Lei Wang; Tahir Rafiq; Michael Chopp
Neural and marrow-derived stromal cell sphere transplantation in a rat model of traumatic brain injury.
Journal of neurosurgery 2002;97(4):935-40.
2002: Xiaoguang Chen; Mark Katakowski; Yi Li; Dunyue Lu; Lei Wang; Lijie Zhang; Jieli Chen; Yongxian Xu; Subhash C Gautam; Asim Mahmood; Michael Chopp
Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: growth factor production.
Journal of neuroscience research 2002;69(5):687-91.
2002: Yi Li; Jieli Chen; X G Chen; Lei Wang; Subhash C Gautam; Yong X Xu; Mark Katakowski; Li Zhang; Mei Lu; Nalini Janakiraman; Michael Chopp
Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recovery.
Neurology 2002;59(4):514-23.
2002: Zheng Gang Zhang; Li Zhang; Manuel Yepes; Quan Jiang; Qingjiang Li; Polly Arniego; Timothy A Coleman; Daniel Lawrence; Michael Chopp
Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke.
Circulation 2002;106(6):740-5.
2002: Jieli Chen; Yi Li; Lei Wang; Mei Lu; Michael Chopp
Caspase inhibition by Z-VAD increases the survival of grafted bone marrow cells and improves functional outcome after MCAo in rats.
Journal of the neurological sciences 2002;199(1-2):17-24.
2002: Lei Wang; Yi Li; Jieli Chen; Subhash C Gautam; Zheng Gang Zhang; Mei Lu; Michael Chopp
Ischemic cerebral tissue and MCP-1 enhance rat bone marrow stromal cell migration in interface culture.
Experimental hematology 2002;30(7):831-6.
2002: Li Zhang; Timothy Schallert; Zheng Gang Zhang; Quan Jiang; Polly Arniego; Qingjiang Li; Mei Lu; Michael Chopp
A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia.
Journal of neuroscience methods 2002;117(2):207-14.
2002: Michael Chopp; Yi Li
Treatment of neural injury with marrow stromal cells.
Lancet neurology 2002;1(2):92-100.
2002: Quan Jiang; Rui Lan Zhang; Zheng Gang Zhang; Robert A Knight; James R Ewing; GuangLiang Ding; Mei Lu; Polly Arniego; Li Zhang; Jiani Hu; QingJiang Li; Michael Chopp
Magnetic resonance imaging characterization of hemorrhagic transformation of embolic stroke in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(5):559-68.
2002: Lei Wang; Yi Li; Xiaoguang Chen; Jieli Chen; Subhash C Gautam; Yongxian Xu; Michael Chopp
MCP-1, MIP-1, IL-8 and ischemic cerebral tissue enhance human bone marrow stromal cell migration in interface culture.
Hematology (Amsterdam, Netherlands) 2002;7(2):113-7.
2002: Zheng Gang Zhang; Li Zhang; Wayne Tsang; Hamid Soltanian-Zadeh; Daniel Morris; Rui Lan Zhang; Anton Goussev; Cecylia Powers; Thomas Yeich; Michael Chopp
Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(4):379-92.
2002: Zheng Gang Zhang; Li Zhang; Quan Jiang; Michael Chopp
Bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse.
Circulation research 2002;90(3):284-8.
2002: Zheng Gang Zhang; Michael Chopp
Vascular endothelial growth factor and angiopoietins in focal cerebral ischemia.
Trends in cardiovascular medicine 2002;12(2):62-6.
2002: Yi Li; Jieli Chen; Michael Chopp
Cell proliferation and differentiation from ependymal, subependymal and choroid plexus cells in response to stroke in rats.
Journal of the neurological sciences 2002;193(2):137-46.
2002: Feng Jiang; Michael Chopp; Mark Katakowski; Kyung-Keun Cho; X Yang; N Hochbaum; L Tong; Tom Mikkelsen
Photodynamic therapy with photofrin reduces invasiveness of malignant human glioma cells.
Lasers in medical science 2002;17(4):280-8.
2002: Zheng Gang Zhang; Li Zhang; S D Croll; Michael Chopp
Angiopoietin-1 reduces cerebral blood vessel leakage and ischemic lesion volume after focal cerebral embolic ischemia in mice.
Neuroscience 2002;113(3):683-7.
2002: Dunyue Lu; Paul Sanberg; Asim Mahmood; Yi Li; Lei Wang; Juan Sanchez-Ramos; Michael Chopp
Intravenous administration of human umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury.
Cell transplantation 2002;11(3):275-81.
2001: Yi Li; Jieli Chen; Lei Wang; Li Zhang; Mei Lu; Michael Chopp
Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Neuroscience letters 2001;316(2):67-70.
2001: Li Zhang; Zheng Gang Zhang; Rui Lan Zhang; Mei Lu; J Adams; P J Elliott; Michael Chopp
Postischemic (6-Hour) treatment with recombinant human tissue plasminogen activator and proteasome inhibitor PS-519 reduces infarction in a rat model of embolic focal cerebral ischemia.
Stroke; a journal of cerebral circulation 2001;32(12):2926-31.
2001: Asim Mahmood; Dunyue Lu; Lei Wang; Yi Li; Mei Lu; Michael Chopp
Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells.
Neurosurgery 2001;49(5):1196-203; discussion 1203-4.
2001: Rui Lan Zhang; Li Zhang; Zheng Gang Zhang; Ying Wang; Mei Lu; Margot C LaPointe; Michael Chopp
A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats.
Annals of neurology 2001;50(5):602-11.
2001: Jieli Chen; Paul Sanberg; Joan C. Dunbar; Lei Wang; Mei Lu; A E Willing; Juan Sanchez-Ramos; Michael Chopp
Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats.
Stroke; a journal of cerebral circulation 2001;32(11):2682-8.
2001: Daniel C Morris; Li Zhang; Zheng Gang Zhang; Mei Lu; K L Berens; P M Brown; Michael Chopp
Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke.
Stroke; a journal of cerebral circulation 2001;32(11):2635-40.
2001: Zheng Gang Zhang; Li Zhang; Wayne Tsang; Anton Goussev; Cecylia Powers; Khang-Loon Ho; Daniel Morris; Susan Smyth; Barry S Coller; Michael Chopp
Dynamic platelet accumulation at the site of the occluded middle cerebral artery and in downstream microvessels is associated with loss of microvascular integrity after embolic middle cerebral artery occlusion.
Brain research 2001;912(2):181-94.
2001: Juan Sanchez-Ramos; Shijie Song; S G Kamath; Tanja Zigova; Alison E Willing; Fernando Cardozo-Pelaez; Todd Stedeford; Michael Chopp; Paul Sanberg
Expression of neural markers in human umbilical cord blood.
Experimental neurology 2001;171(1):109-15.
2001: Jieli Chen; Yi Li; Lei Wang; Mei Lu; Xueguo Zhang; Michael Chopp
Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats.
Journal of the neurological sciences 2001;189(1-2):49-57.
2001: Dunyue Lu; Yi Li; Lei Wang; Jieli Chen; Asim Mahmood; Michael Chopp
Intraarterial administration of marrow stromal cells in a rat model of traumatic brain injury.
Journal of neurotrauma 2001;18(8):813-9.
2001: Yi Li; Jieli Chen; Lei Wang; Mei Lu; Michael Chopp
Treatment of stroke in rat with intracarotid administration of marrow stromal cells.
Neurology 2001;56(12):1666-72.
2001: Donald Seyfried; R Veyna; Yuxia Han; K Li; Naimei Tang; Russell Betts; Shantel Weinsheimer; Michael Chopp; John Anagli
A selective cysteine protease inhibitor is non-toxic and cerebroprotective in rats undergoing transient middle cerebral artery ischemia.
Brain research 2001;901(1-2):94-101.
2001: Zheng Gang Zhang; Wayne Tsang; Li Zhang; Cecylia Powers; Michael Chopp
Up-regulation of neuropilin-1 in neovasculature after focal cerebral ischemia in the adult rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(5):541-9.
2001: Asim Mahmood; Dunyue Lu; L Yi; Jieli Chen; Michael Chopp
Intracranial bone marrow transplantation after traumatic brain injury improving functional outcome in adult rats.
Journal of neurosurgery 2001;94(4):589-95.
2001: J Chen; Yi Li; Lei Wang; Zheng Gang Zhang; D Lu; Mei Lu; Michael Chopp
Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 2001;32(4):1005-11.
2001: Michael A Jacobs; Panayiotis Mitsias; Hamid Soltanian-Zadeh; Sunitha Santhakumar; Amir Ghanei; R Hammond; DJ Peck; Michael Chopp; Suresh C Patel
Multiparametric MRI tissue characterization in clinical stroke with correlation to clinical outcome: part 2.
Stroke; a journal of cerebral circulation 2001;32(4):950-7.
2001: Michael A Jacobs; Zheng Gang Zhang; Robert A Knight; Hamid Soltanian-Zadeh; Anton Goussev; DJ Peck; Michael Chopp
A model for multiparametric mri tissue characterization in experimental cerebral ischemia with histological validation in rat: part 1.
Stroke; a journal of cerebral circulation 2001;32(4):943-9.
2001: D Lu; Asim Mahmood; Lei Wang; Yi Li; Mei Lu; Michael Chopp
Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome.
Neuroreport 2001;12(3):559-63.
2001: R Paul; Zheng Gang Zhang; Brian P Eliceiri; Quan Jiang; A D Boccia; Rui Lan Zhang; Michael Chopp; David A Cheresh
Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke.
Nature medicine 2001;7(2):222-7.
2001: Quan Jiang; James R Ewing; Zheng Gang Zhang; Rui Lan Zhang; Jiani Hu; George Divine; Polly Arniego; Qing Jiang Li; Michael Chopp
Magnetization transfer MRI: application to treatment of middle cerebral artery occlusion in rat.
Journal of magnetic resonance imaging : JMRI 2001;13(2):178-84.
2001: Rui Lan Zhang; Zheng Gang Zhang; Li Zhang; Michael Chopp
Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia.
Neuroscience 2001;105(1):33-41.
2001: Yi Li; Jieli Chen; Michael Chopp
Adult bone marrow transplantation after stroke in adult rats.
Cell transplantation 2001;10(1):31-40.
2000: Zheng Gang Zhang; Li Zhang; Quan Jiang; Rui Lan Zhang; K Davies; C Powers; N v Bruggen; Michael Chopp
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain.
The Journal of clinical investigation 2000;106(7):829-38.
2000: Rui Lan Zhang; Li Zhang; Quan Jiang; Zheng Gang Zhang; Anton Goussev; Michael Chopp
Postischemic intracarotid treatment with TNK-tPA reduces infarct volume and improves neurological deficits in embolic stroke in the unanesthetized rat.
Brain research 2000;878(1-2):64-71.
2000: Michael Chopp; X H Zhang; Joan C. Dunbar; Lei Wang; Jieli Chen; D Lu; Mei Lu; Mark L Rosenblum
Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation.
Neuroreport 2000;11(13):3001-5.
2000: D C Morris; K Davies; Zheng Gang Zhang; Michael Chopp
Measurement of cerebral microvessel diameters after embolic stroke in rat using quantitative laser scanning confocal microscopy.
Brain research 2000;876(1-2):31-6.
2000: Yi Li; Michael Chopp; Jieli Chen; Lei Wang; Subhash C Gautam; Y X Xu; Zheng Gang Zhang
Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(9):1311-9.
2000: S C Cramer; Michael Chopp
Recovery recapitulates ontogeny.
Trends in neurosciences 2000;23(6):265-71.
2000: Michael A Jacobs; Robert A Knight; Hamid Soltanian-Zadeh; Z G Zheng; Anton Goussev; DJ Peck; JP Windham; Michael Chopp
Unsupervised segmentation of multiparameter MRI in experimental cerebral ischemia with comparison to T2, diffusion, and ADC MRI parameters and histopathological validation.
Journal of magnetic resonance imaging : JMRI 2000;11(4):425-37.
2000: Li Zhang; J Chen; Yi Li; Zheng Gang Zhang; Michael Chopp
Quantitative measurement of motor and somatosensory impairments after mild (30 min) and severe (2 h) transient middle cerebral artery occlusion in rats.
Journal of the neurological sciences 2000;174(2):141-6.
2000: J Chen; Yi Li; Michael Chopp
Intracerebral transplantation of bone marrow with BDNF after MCAo in rat.
Neuropharmacology 2000;39(5):711-6.
2000: Quan Jiang; Rui Lan Zhang; Zheng Gang Zhang; James R Ewing; P Jiang; George Divine; Robert A Knight; Michael Chopp
Magnetic resonance imaging indexes of therapeutic efficacy of recombinant tissue plasminogen activator treatment of rat at 1 and 4 hours after embolic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(1):21-7.
1999: Zheng Gang Zhang; Michael Chopp; Anton Goussev; Dunyue Lu; Daniel Morris; Wayne Tsang; Cecylia Powers; Khang-Loon Ho
Cerebral microvascular obstruction by fibrin is associated with upregulation of PAI-1 acutely after onset of focal embolic ischemia in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(24):10898-907.
1999: senol kaya; Asim Mahmood; Yi Li; E Yavuz; Michael Chopp
Expression of cell cycle proteins (cyclin D1 and cdk4) after controlled cortical impact in rat brain.
Journal of neurotrauma 1999;16(12):1187-96.
1999: J Chen; Michael Chopp; Yi Li
Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat.
Journal of the neurological sciences 1999;171(1):24-30.
1999: Zheng Gang Zhang; Michael Chopp; Dunyue Lu; T Wayne; Rui Lan Zhang; Daniel Morris
Receptor tyrosine kinase tie 1 mRNA is upregulated on cerebral microvessels after embolic middle cerebral artery occlusion in rat.
Brain research 1999;847(2):338-42.
1999: A J Thomas; Russ P Nockels; H Q Pan; Christopher I Shaffrey; Michael Chopp
Progesterone is neuroprotective after acute experimental spinal cord trauma in rats.
Spine 1999;24(20):2134-8.
1999: Zheng Gang Zhang; L Bower; Rui Lan Zhang; S Chen; JP Windham; Michael Chopp
Three-dimensional measurement of cerebral microvascular plasma perfusion, glial fibrillary acidic protein and microtubule associated protein-2 immunoreactivity after embolic stroke in rats: a double fluorescent labeled laser-scanning confocal microscopic study.
Brain research 1999;844(1-2):55-66.
1999: S Sahin Kaya; Asim Mahmood; Yi Li; E Yavuz; Michael Chopp
Expression of nestin after traumatic brain injury in rat brain.
Brain research 1999;840(1-2):153-7.
1999: Yi Li; Michael Chopp
Temporal profile of nestin expression after focal cerebral ischemia in adult rat.
Brain research 1999;838(1-2):1-10.
1999: Moo-Young Ahn; Zheng Gang Zhang; W Tsang; Michael Chopp
Endogenous plasminogen activator expression after embolic focal cerebral ischemia in mice.
Brain research 1999;837(1-2):169-76.
1999: Michael A Jacobs; Robert A Knight; JP Windham; Zheng Gang Zhang; Hamid Soltanian-Zadeh; Anton Goussev; DJ Peck; Michael Chopp
Identification of cerebral ischemic lesions in rat using Eigenimage filtered magnetic resonance imaging.
Brain research 1999;837(1-2):83-94.
1999: Kyung-Keun Cho; Tom Mikkelsen; Y J Lee; Feng Jiang; Michael Chopp; Mark L Rosenblum
The role of protein kinase Calpha in U-87 glioma invasion.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1999;17(5-6):447-61.
1999: D C Morris; Zheng Gang Zhang; K Davies; Joseph D Fenstermacher; Michael Chopp
High resolution quantitation of microvascular plasma perfusion in non-ischemic and ischemic rat brain by laser-scanning confocal microscopy.
Brain research. Brain research protocols 1999;4(2):185-91.
1999: Moo-Young Ahn; Zheng Gang Zhang; Li Zhang; Michael Chopp
The effect of age on expression of endogenous plasminogen activators after focal cerebral ischemia in mice.
Brain research 1999;833(1):112-6.
1999: Michael Chopp; Yi Li; N Jiang
Increase in apoptosis and concomitant reduction of ischemic lesion volume and evidence for synaptogenesis after transient focal cerebral ischemia in rat treated with staurosporine.
Brain research 1999;828(1-2):197-201.
1999: James R Ewing; Quan Jiang; Michael D Boska; Zheng Gang Zhang; Stephen L Brown; G H Li; George Divine; Michael Chopp
T1 and magnetization transfer at 7 Tesla in acute ischemic infarct in the rat.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;41(4):696-705.
1999: Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp; J A Zivin
Thrombolysis with tissue plasminogen activator alters adhesion molecule expression in the ischemic rat brain.
Stroke; a journal of cerebral circulation 1999;30(3):624-9.
1999: senol kaya; Asim Mahmood; Yi Li; E Yavuz; M Göksel; Michael Chopp
Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain.
Brain research 1999;818(1):23-33.
1999: Rui Lan Zhang; Zheng Gang Zhang; Michael Chopp
Increased therapeutic efficacy with rt-PA and anti-CD18 antibody treatment of stroke in the rat.
Neurology 1999;52(2):273-9.
1999: Michael Chopp; Rui Lan Zhang; Zheng Gang Zhang; Quan Jiang
The clot thickens--thrombolysis and combination therapies.
Acta neurochirurgica. Supplement 1999;73():67-71.
1999: Zheng Gang Zhang; K Davies; J Prostak; Joseph D Fenstermacher; Michael Chopp
Quantitation of microvascular plasma perfusion and neuronal microtubule-associated protein in ischemic mouse brain by laser-scanning confocal microscopy.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(1):68-78.
1998: Anton Goussev; Zheng Gang Zhang; D C Anderson; Michael Chopp
P-selectin antibody reduces hemorrhage and infarct volume resulting from MCA occlusion in the rat.
Journal of the neurological sciences 1998;161(1):16-22.
1998: Rui Lan Zhang; Michael Chopp; Zheng Gang Zhang; George Divine
Early (1 h) administration of tissue plasminogen activator reduces infarct volume without increasing hemorrhagic transformation after focal cerebral embolization in rats.
Journal of the neurological sciences 1998;160(1):1-8.
1998: Yi Li; N Jiang; C Powers; Michael Chopp
Neuronal damage and plasticity identified by microtubule-associated protein 2, growth-associated protein 43, and cyclin D1 immunoreactivity after focal cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1998;29(9):1972-80; discussion 1980-1.
1998: Quan Jiang; Rui Lan Zhang; Zheng Gang Zhang; James R Ewing; George Divine; Michael Chopp
Diffusion-, T2-, and perfusion-weighted nuclear magnetic resonance imaging of middle cerebral artery embolic stroke and recombinant tissue plasminogen activator intervention in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(7):758-67.
1998: Luis D'Olhaberriague; K M A Welch; Vijaya Nagesh; C Gymnopoulos; HH Mansbach; J W Hugg; Michael D Boska; Robert A Knight; Lonni R Schultz; Steven R Levine; Michael Chopp
Preliminary clinical-radiological assessment of a MR tissue signature model in human stroke.
Journal of the neurological sciences 1998;156(2):158-66.
1998: Yi Li; C Powers; N Jiang; Michael Chopp
Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat.
Journal of the neurological sciences 1998;156(2):119-32.
1998: Quan Jiang; Zheng Gang Zhang; Rui Lan Zhang; James R Ewing; George Divine; P Jiang; Michael Chopp
Diffusion, perfusion, and T2 magnetic resonance imaging of anti-intercellular adhesion molecule 1 antibody treatment of transient middle cerebral artery occlusion in rat.
Brain research 1998;788(1-2):191-201.
1998: N Jiang; Michael Chopp; S Chahwala
Neutrophil inhibitory factor treatment of focal cerebral ischemia in the rat.
Brain research 1998;788(1-2):25-34.
1998: Rui Lan Zhang; Michael Chopp; Zheng Gang Zhang; N Jiang; C Powers
The expression of P- and E-selectins in three models of middle cerebral artery occlusion.
Brain research 1998;785(2):207-14.
1998: Zheng Gang Zhang; Michael Chopp; Anton Goussev; Cecylia Powers
Cerebral vessels express interleukin 1beta after focal cerebral ischemia.
Brain research 1998;784(1-2):210-7.
1998: Feng Jiang; L Lilge; M Belcuig; G Singh; J Grenier; Yi Li; Michael Chopp
Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain.
Lasers in surgery and medicine 1998;23(3):161-6.
1998: Feng Jiang; L Lilge; J Grenier; Yi Li; M D Wilson; Michael Chopp
Photodynamic therapy of U87 human glioma in nude rat using liposome-delivered photofrin.
Lasers in surgery and medicine 1998;22(2):74-80.
1997: Donald Seyfried; Yuxia Han; Z Zheng; N Day; Kamiar Moin; Sandra Rempel; Bonnie F Sloane; Michael Chopp
Cathepsin B and middle cerebral artery occlusion in the rat.
Journal of neurosurgery 1997;87(5):716-23.
1997: Zheng Gang Zhang; Michael Chopp; Rui Lan Zhang; Anton Goussev
A mouse model of embolic focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(10):1081-8.
1997: Yi Li; Michael Chopp; C Powers
Granule cell apoptosis and protein expression in hippocampal dentate gyrus after forebrain ischemia in the rat.
Journal of the neurological sciences 1997;150(2):93-102.
1997: Rui Lan Zhang; Michael Chopp; Zheng Gang Zhang; Quan Jiang; James R Ewing
A rat model of focal embolic cerebral ischemia.
Brain research 1997;766(1-2):83-92.
1997: Yi Li; Michael Chopp; Cecylia Powers; N Jiang
Apoptosis and protein expression after focal cerebral ischemia in rat.
Brain research 1997;765(2):301-12.
1997: Yi Li; Michael Chopp; Cecylia Powers; N Jiang
Immunoreactivity of cyclin D1/cdk4 in neurons and oligodendrocytes after focal cerebral ischemia in rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(8):846-56.
1997: Feng Jiang; L Lilge; B Logie; Yi Li; Michael Chopp
Photodynamic therapy of 9L gliosarcoma with liposome-delivered photofrin.
Photochemistry and photobiology 1997;65(4):701-6.
1997: N Jiang; E A Kowaluk; C H Lee; H Mazdiyasni; Michael Chopp
Adenosine kinase inhibition protects brain against transient focal ischemia in rats.
European journal of pharmacology 1997;320(2-3):131-7.
1997: Zheng Gang Zhang; Rui Lan Zhang; Quan Jiang; S B Raman; L Cantwell; Michael Chopp
A new rat model of thrombotic focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(2):123-35.
1997: Zheng Gang Zhang; Michael Chopp; Cecylia Powers
Temporal profile of microglial response following transient (2 h) middle cerebral artery occlusion.
Brain research 1997;744(2):189-98.
1997: Quan Jiang; Michael Chopp; Zheng Gang Zhang; Robert A Knight; Michael A Jacobs; JP Windham; DJ Peck; James R Ewing; K M A Welch
The temporal evolution of MRI tissue signatures after transient middle cerebral artery occlusion in rat.
Journal of the neurological sciences 1997;145(1):15-23.
1996: Rui Lan Zhang; Michael Chopp; Zheng Gang Zhang; M L Phillips; C L Rosenbloom; R Cruz; A Manning
E-selectin in focal cerebral ischemia and reperfusion in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(6):1126-36.
1996: Michael Chopp; M O Dereski; L Madigan; Feng Jiang; B Logie
Sensitivity of 9L gliosarcomas to photodynamic therapy.
Radiation research 1996;146(4):461-5.
1996: Michael Chopp; L Madigan; M Dereski; Feng Jiang; Yi Li
Photodynamic therapy of human glioma (U87) in the nude rat.
Photochemistry and photobiology 1996;64(4):707-11.
1996: N Jiang; Michael Chopp; D Stein; H Feit
Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats.
Brain research 1996;735(1):101-7.
1996: N Jiang; S P Finklestein; T Do; C G Caday; M Charette; Michael Chopp
Delayed intravenous administration of basic fibroblast growth factor (bFGF) reduces infarct volume in a model of focal cerebral ischemia/reperfusion in the rat.
Journal of the neurological sciences 1996;139(2):173-9.
1996: Zheng Gang Zhang; D Reif; J Macdonald; W X Tang; D K Kamp; R J Gentile; W C Shakespeare; R J Murray; Michael Chopp
ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):599-604.
1996: Michael Chopp; Yi Li; N Jiang; Rui Lan Zhang; J Prostak
Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):578-84.
1996: Q Chen; Michael Chopp; L Madigan; M O Dereski; F W Hetzel
Damage threshold of normal rat brain in photodynamic therapy.
Photochemistry and photobiology 1996;64(1):163-7.
1996: N Jiang; Rui Lan Zhang; B M Baron; Michael Chopp
Administration of a competitive NMDA antagonist MDL-100,453 reduces infarct size after permanent middle cerebral artery occlusion in rat.
Journal of the neurological sciences 1996;138(1-2):36-41.
1996: Rui Lan Zhang; Michael Chopp; W X Tang; Zheng Gang Zhang; S D Putney; R M Starzyk
Synthetic peptide derived from the Bordetella pertussis bacterium reduces infarct volume after transient middle cerebral artery occlusion in the rat.
Neurology 1996;46(5):1437-41.
1996: Michael Chopp
Spreading depression.
Cephalalgia : an international journal of headache 1996;16(2):77.
1996: Michael Chopp; P H Chan; C Y Hsu; M E Cheung; T P Jacobs
DNA damage and repair in central nervous system injury: National Institute of Neurological Disorders and Stroke Workshop Summary.
Stroke; a journal of cerebral circulation 1996;27(3):363-9.
1996: Michael Chopp; Zheng Gang Zhang
Anti-adhesion molecule and nitric oxide protection strategies in ischemic stroke.
Current opinion in neurology 1996;9(1):68-72.
1996: Michael Chopp; Rui Lan Zhang; N Jiang
The role of adhesion molecules in reducing cerebral ischemic cell damage.
Advances in neurology 1996;71():315-26; discussion 326-7.
1996: Michael Chopp; Yi Li
Apoptosis in focal cerebral ischemia.
Acta neurochirurgica. Supplement 1996;66():21-6.
1995: N Jiang; M Moyle; H R Soule; W E Rote; Michael Chopp
Neutrophil inhibitory factor is neuroprotective after focal ischemia in rats.
Annals of neurology 1995;38(6):935-42.
1995: Zheng Gang Zhang; Michael Chopp; W X Tang; N Jiang; Rui Lan Zhang
Postischemic treatment (2-4 h) with anti-CD11b and anti-CD18 monoclonal antibodies are neuroprotective after transient (2 h) focal cerebral ischemia in the rat.
Brain research 1995;698(1-2):79-85.
1995: Rui Lan Zhang; Michael Chopp; N Jiang; W X Tang; J Prostak; A M Manning; D C Anderson
Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the Wistar rat.
Stroke; a journal of cerebral circulation 1995;26(8):1438-42; discussion 1443.
1995: Yi Li; Michael Chopp; N Jiang; Zheng Gang Zhang; C Zaloga
Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1995;26(7):1252-7; discussion 1257-8.
1995: Rui Lan Zhang; Michael Chopp; C Zaloga; Zheng Gang Zhang; N Jiang; Subhash C Gautam; W X Tang; W Tsang; D C Anderson; A M Manning
The temporal profiles of ICAM-1 protein and mRNA expression after transient MCA occlusion in the rat.
Brain research 1995;682(1-2):182-8.
1995: Yi Li; V G Sharov; N Jiang; C Zaloga; Hani N Sabbah; Michael Chopp
Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat.
The American journal of pathology 1995;146(5):1045-51.
1995: Yi Li; Michael Chopp; N Jiang; F Yao; C Zaloga
Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(3):389-97.
1995: K Hurd; Michael Chopp; A M Vande Linde; Yi Li; Horace Spencer
Effects of moderate hyperglycemia on the temporal profile of brain tissue intracellular pH and [Mg2+] after global cerebral ischemia in rats.
Journal of the neurological sciences 1995;129(2):90-6.
1995: J S Kim; Subhash C Gautam; Michael Chopp; C Zaloga; M L Jones; Peter A Ward; K M A Welch
Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat.
Journal of neuroimmunology 1995;56(2):127-34.
1995: Yi Li; Michael Chopp; Zheng Gang Zhang; Rui Lan Zhang
Expression of glial fibrillary acidic protein in areas of focal cerebral ischemia accompanies neuronal expression of 72-kDa heat shock protein.
Journal of the neurological sciences 1995;128(2):134-42.
1995: J S Kim; Michael Chopp; H Chen; Steven R Levine; J L Carey; K M A Welch
Adhesive glycoproteins CD11a and CD18 are upregulated in the leukocytes from patients with ischemic stroke and transient ischemic attacks.
Journal of the neurological sciences 1995;128(1):45-50.
1995: Jong S Kim; Michael Chopp; Subhash C Gautam
High dose methylprednisolone therapy reduces expression of JE/MCP-1 mRNA and macrophage accumulation in the ischemic rat brain.
Journal of the neurological sciences 1995;128(1):28-35.
1995: M O Dereski; L Madigan; Michael Chopp
The effect of hypothermia and hyperthermia on photodynamic therapy of normal brain.
Neurosurgery 1995;36(1):141-5; discussion 145-6.
1995: Yi Li; Michael Chopp; N Jiang; C Zaloga
In situ detection of DNA fragmentation after focal cerebral ischemia in mice.
Brain research. Molecular brain research 1995;28(1):164-8.
1995: Zheng Gang Zhang; Michael Chopp; F Bailey; Tadeusz Malinski
Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion.
Journal of the neurological sciences 1995;128(1):22-7.
1994: Zheng Gang Zhang; Michael Chopp; K I Maynard; M A Moskowitz
Cerebral blood flow changes during cortical spreading depression are not altered by inhibition of nitric oxide synthesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(6):939-43.
1994: Quan Jiang; Michael Chopp; Zheng Gang Zhang; Joseph A Helpern; Roger J Ordidge; James R Ewing; P Jiang; B A Marchese
The effect of hypothermia on transient focal ischemia in rat brain evaluated by diffusion- and perfusion-weighted NMR imaging.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(5):732-41.
1994: Rui Lan Zhang; Michael Chopp; Yi Li; C Zaloga; N Jiang; M L Jones; M Miyasaka; Peter A Ward
Anti-ICAM-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in the rat.
Neurology 1994;44(9):1747-51.
1994: Zheng Gang Zhang; Michael Chopp; Subhash C Gautam; C Zaloga; Rui Lan Zhang; H H Schmidt; Jennifer Pollock; U Förstermann
Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal cerebral ischemia in rat.
Brain research 1994;654(1):85-95.
1994: Rui Lan Zhang; Michael Chopp; H Chen; JH Garcia
Temporal profile of ischemic tissue damage, neutrophil response, and vascular plugging following permanent and transient (2H) middle cerebral artery occlusion in the rat.
Journal of the neurological sciences 1994;125(1):3-10.
1994: Robert A Knight; M O Dereski; Joseph A Helpern; Roger J Ordidge; Michael Chopp
Magnetic resonance imaging assessment of evolving focal cerebral ischemia. Comparison with histopathology in rats.
Stroke; a journal of cerebral circulation 1994;25(6):1252-61; discussion 1261-2.
1994: Michael Chopp; Rui Lan Zhang; H Chen; Yi Li; N Jiang; J R Rusche
Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats.
Stroke; a journal of cerebral circulation 1994;25(4):869-75; discussion 875-6.
1994: Yi Li; Michael Chopp; Zheng Gang Zhang; C Zaloga; L Niewenhuis; Subhash C Gautam
p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats.
Stroke; a journal of cerebral circulation 1994;25(4):849-55; discussion 855-6.
1994: H Chen; Michael Chopp; Rui Lan Zhang; G Bodzin; Q Chen; J R Rusche; R F Todd
Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat.
Annals of neurology 1994;35(4):458-63.
1994: Y Takanashi; Michael Chopp; K Nakajima
[Magnetoencephalographic observation of cortical spreading depression elicited by experimental focal brain ischemia in rats].
Nō to shinkei = Brain and nerve 1994;46(3):245-50.
1994: H D Portnoy; Michael Chopp
Intracranial fluid dynamics. Interrelationship of CSF and vascular phenomena. 1983.
Pediatric neurosurgery 1994;20(1):92-7; discussion 98.
1993: Quan Jiang; Zheng Gang Zhang; Michael Chopp; Joseph A Helpern; Roger J Ordidge; JH Garcia; B A Marchese; Z X Qing; Robert A Knight
Temporal evolution and spatial distribution of the diffusion constant of water in rat brain after transient middle cerebral artery occlusion.
Journal of the neurological sciences 1993;120(2):123-30.
1993: Yi Li; Michael Chopp; Zheng Gang Zhang; Rui Lan Zhang; JH Garcia
Neuronal survival is associated with 72-kDa heat shock protein expression after transient middle cerebral artery occlusion in the rat.
Journal of the neurological sciences 1993;120(2):187-94.
1993: Zheng Gang Zhang; Michael Chopp; C Zaloga; Jennifer Pollock; U Förstermann
Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1993;24(12):2016-21; discussion 2021-2.
1993: H Chen; Michael Chopp; Lonni R Schultz; G Bodzin; JH Garcia
Sequential neuronal and astrocytic changes after transient middle cerebral artery occlusion in the rat.
Journal of the neurological sciences 1993;118(2):109-6.
1993: Rui Lan Zhang; Michael Chopp; H Chen; JH Garcia; Zheng Gang Zhang
Postischemic (1 hour) hypothermia significantly reduces ischemic cell damage in rats subjected to 2 hours of middle cerebral artery occlusion.
Stroke; a journal of cerebral circulation 1993;24(8):1235-40.
1993: Zheng Gang Zhang; Michael Chopp; H Chen
Duration dependent post-ischemic hypothermia alleviates cortical damage after transient middle cerebral artery occlusion in the rat.
Journal of the neurological sciences 1993;117(1-2):240-4.
1993: Q Chen; Michael Chopp; G Bodzin; H Chen
Temperature modulation of cerebral depolarization during focal cerebral ischemia in rats: correlation with ischemic injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(3):389-94.
1993: Tadeusz Malinski; F Bailey; Zheng Gang Zhang; Michael Chopp
Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(3):355-8.
1993: JH Garcia; Y Yoshida; H Chen; Yi Li; Zheng Gang Zhang; J Lian; S Chen; Michael Chopp
Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat.
The American journal of pathology 1993;142(2):623-35.
1993: Michael Chopp
The roles of heat shock proteins and immediate early genes in central nervous system normal function and pathology.
Current opinion in neurology and neurosurgery 1993;6(1):6-10.
1993: M O Dereski; Michael Chopp; Robert A Knight; L C Rodolosi; JH Garcia
The heterogeneous temporal evolution of focal ischemic neuronal damage in the rat.
Acta neuropathologica 1993;85(3):327-33.
1993: Joseph A Helpern; M O Dereski; Robert A Knight; Roger J Ordidge; Michael Chopp; Z X Qing
Histopathological correlations of nuclear magnetic resonance imaging parameters in experimental cerebral ischemia.
Magnetic resonance imaging 1993;11(2):241-6.
1993: A M Vande Linde; Michael Chopp; S A Lee; Lonni R Schultz; K M A Welch
Post-ischemic brain tissue alkalosis suppressed by U74006F.
Journal of the neurological sciences 1993;114(1):36-9.
1993: Subhash C Gautam; C J Noth; L M Niewenhuis; Nalini Janakiraman; J S Kim; Michael Chopp
Transforming growth factor beta-1 (TGF-beta 1) potentiates IL1 alpha-induced IL6 mRNA and cytokine protein production in a human astrocytoma cell line.
Oncology research 1993;5(10-11):423-32.
1992: Y Yoshida; M O Dereski; JH Garcia; F W Hetzel; Michael Chopp
Neuronal injury after photoactivation of photofrin II.
The American journal of pathology 1992;141(4):989-97.
1992: Q Chen; Michael Chopp; M O Dereski; B C Wilson; M S Patterson; A Schreiber; F W Hetzel
The effect of light fluence rate in photodynamic therapy of normal rat brain.
Radiation research 1992;132(1):120-3.
1992: Q Chen; Michael Chopp; H Chen; Norman Tepley
Magnetoencephalography of focal cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1992;23(9):1299-303.
1992: Yi Li; Michael Chopp; JH Garcia; Y Yoshida; Zheng Gang Zhang; Steven R Levine
Distribution of the 72-kd heat-shock protein as a function of transient focal cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1992;23(9):1292-8.
1992: Q Chen; B C Wilson; M O Dereski; M S Patterson; Michael Chopp; F W Hetzel
Effects of light beam size on fluence distribution and depth of necrosis in superficially applied photodynamic therapy of normal rat brain.
Photochemistry and photobiology 1992;56(3):379-84.
1992: F W Hetzel; Michael Chopp; M O Dereski
Variations in pO2 and pH response to hyperthermia: dependence on transplant site and duration of treatment.
Radiation research 1992;131(2):152-6.
1992: H Chen; Michael Chopp; Zheng Gang Zhang; JH Garcia
The effect of hypothermia on transient middle cerebral artery occlusion in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(4):621-8.
1992: Michael Chopp; Yi Li; Zheng Gang Zhang; Svend O Freytag
p53 expression in brain after middle cerebral artery occlusion in the rat.
Biochemical and biophysical research communications 1992;182(3):1201-7.
1992: H Chen; Michael Chopp; A M Vande Linde; M O Dereski; JH Garcia; K M A Welch
The effects of post-ischemic hypothermia on the neuronal injury and brain metabolism after forebrain ischemia in the rat.
Journal of the neurological sciences 1992;107(2):191-8.
1992: Michael Chopp; Yi Li; M O Dereski; Steven R Levine; Y Yoshida; JH Garcia
Hypothermia reduces 72-kDa heat-shock protein induction in rat brain after transient forebrain ischemia.
Stroke; a journal of cerebral circulation 1992;23(1):104-7.
1992: R A Van Dyke; S Mostafapour; Harold Michael Marsh; Yi Li; Michael Chopp
Immunocytochemical detection of the 72-kDa heat shock protein in halothane--induced hepatotoxicity in rats.
Life sciences 1992;50(7):PL41-5.
1992: Y Yoshida; M O Dereski; JH Garcia; F W Hetzel; Michael Chopp
Photoactivated Photofrin II: astrocytic swelling precedes endothelial injury in rat brain.
Journal of neuropathology and experimental neurology 1992;51(1):91-100.
1992: H Chen; Michael Chopp; Quan Jiang; JH Garcia
Neuronal damage, glial response and cerebral metabolism after hypothermic forebrain ischemia in the rat.
Acta neuropathologica 1992;84(2):184-9.
1992: Yi Li; Michael Chopp; Y Yoshida; Steven R Levine
Distribution of 72-kDa heat-shock protein in rat brain after hyperthermia.
Acta neuropathologica 1992;84(1):94-9.
1991: A M Vande Linde; Michael Chopp; H Chen; Joseph A Helpern; Robert A Knight; Lonni R Schultz; K M A Welch
Chronic changes in the brain Mg2+ concentration after forebrain ischemia in the rat.
Metabolic brain disease 1991;6(4):199-206.
1991: Quan Jiang; Michael Chopp; F W Hetzel
In vivo 31P NMR study of combined hyperthermia and photodynamic therapies of mammary carcinoma in the mouse.
Photochemistry and photobiology 1991;54(5):795-9.
1991: Y Takanashi; Michael Chopp; Steven R Levine; J Kim; John E Moran; Norman Tepley; Q Chen; Gregory Barkley; K M A Welch
Magnetic fields associated with anoxic depolarization in anesthetized rats.
Brain research 1991;562(1):13-6.
1991: Quan Jiang; Robert A Knight; Michael Chopp; Joseph A Helpern; Roger J Ordidge; Z X Qing; F W Hetzel
1H magnetic resonance imaging of normal brain tissue response to photodynamic therapy.
Neurosurgery 1991;29(4):538-46.
1991: Quan Jiang; Michael Chopp; K Kovich; C Johnson; F W Hetzel
Dose-dependent thermal response of tumor pH and energy metabolism evaluated by in vivo 31P NMR spectroscopy and microelectrodes.
Radiation research 1991;127(2):177-83.
1991: H Chen; Michael Chopp; K M A Welch
Effect of mild hyperthermia on the ischemic infarct volume after middle cerebral artery occlusion in the rat.
Neurology 1991;41(7):1133-5.
1991: M O Dereski; Michael Chopp; JH Garcia; F W Hetzel
Depth measurements and histopathological characterization of photodynamic therapy generated normal brain necrosis as a function of incident optical energy dose.
Photochemistry and photobiology 1991;54(1):109-12.
1991: Robert A Knight; Roger J Ordidge; Joseph A Helpern; Michael Chopp; L C Rodolosi; DJ Peck
Temporal evolution of ischemic damage in rat brain measured by proton nuclear magnetic resonance imaging.
Stroke; a journal of cerebral circulation 1991;22(6):802-8.
1991: Michael Chopp; H Chen; M O Dereski; JH Garcia
Mild hypothermic intervention after graded ischemic stress in rats.
Stroke; a journal of cerebral circulation 1991;22(1):37-43.
1991: Michael Chopp; Yi Li; M O Dereski; Steven R Levine; Y Yoshida; JH Garcia
Neuronal injury and expression of 72-kDa heat-shock protein after forebrain ischemia in the rat.
Acta neuropathologica 1991;83(1):66-71.
1990: Michael Chopp; H Chen; A M Vande Linde; E Brown; K M A Welch
Time course of postischemic intracellular alkalosis reflects the duration of ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(6):860-5.
1990: Michael Chopp; Q Chen; M O Dereski; F W Hetzel
Chronic metabolic measurements of normal brain tissue response to photodynamic therapy.
Photochemistry and photobiology 1990;52(5):1033-6.
1990: F W Hetzel; Michael Chopp
Changes in muscle pH following hyperthermia.
Radiation research 1990;122(3):229-33.
1990: Michael Chopp; F W Hetzel; Quan Jiang
Dose-dependent metabolic response of mammary carcinoma to photodynamic therapy.
Radiation research 1990;121(3):288-94.
1990: Michael Chopp; A M Vande Linde; H Chen; Robert A Knight; Joseph A Helpern; K M A Welch
Chronic cerebral intracellular alkalosis following forebrain ischemic insult in rats.
Stroke; a journal of cerebral circulation 1990;21(3):463-6.
1989: M O Dereski; Michael Chopp; Q Chen; F W Hetzel
Normal brain tissue response to photodynamic therapy: histology, vascular permeability and specific gravity.
Photochemistry and photobiology 1989;50(5):653-7.
1989: Michael Chopp; C D Tidwell; Y J Lee; Robert A Knight; Joseph A Helpern; K M A Welch
Reduction of hyperthermic ischemic acidosis by a conditioning event in cats.
Stroke; a journal of cerebral circulation 1989;20(10):1357-60.
1989: Michael Chopp; H Chen; K L Ho; M O Dereski; E Brown; F W Hetzel; K M A Welch
Transient hyperthermia protects against subsequent forebrain ischemic cell damage in the rat.
Neurology 1989;39(10):1396-8.
1989: Michael Chopp; Robert A Knight; C D Tidwell; Joseph A Helpern; E Brown; K M A Welch
The metabolic effects of mild hypothermia on global cerebral ischemia and recirculation in the cat: comparison to normothermia and hyperthermia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(2):141-8.
1989: J E Mesina; R H Page; F W Hetzel; Michael Chopp
Administration of L-2-oxothiazolidine-4-carboxylate increases glutathione levels in rat brain.
Brain research 1989;478(1):181-3.
1989: F W Hetzel; K Avery; Michael Chopp
Hyperthermic "dose" dependent changes in intralesional pH.
International journal of radiation oncology, biology, physics 1989;16(1):183-6.
1988: Michael Chopp; K M A Welch; C D Tidwell; Robert A Knight; Joseph A Helpern
Effect of mild hyperthermia on recovery of metabolic function after global cerebral ischemia in cats.
Stroke; a journal of cerebral circulation 1988;19(12):1521-5.
1988: Michael Chopp; K M A Welch; C D Tidwell; Joseph A Helpern
Global cerebral ischemia and intracellular pH during hyperglycemia and hypoglycemia in cats.
Stroke; a journal of cerebral circulation 1988;19(11):1383-7.
1988: Steven R Levine; K M A Welch; Joseph A Helpern; Michael Chopp; R Bruce; J Selwa; M B Smith
Prolonged deterioration of ischemic brain energy metabolism and acidosis associated with hyperglycemia: human cerebral infarction studied by serial 31P NMR spectroscopy.
Annals of neurology 1988;23(4):416-8.
1987: Michael Chopp; H Farmer; F Hetzel; A P Schaap
In vivo 31P-NMR spectroscopy of mammary carcinoma subjected to subcurative photodynamic therapy.
Photochemistry and photobiology 1987;46(5):819-22.
1987: Michael Chopp; Stanley Frinak; D R Walton; M B Smith; K M A Welch
Intracellular acidosis during and after cerebral ischemia: in vivo nuclear magnetic resonance study of hyperglycemia in cats.
Stroke; a journal of cerebral circulation 1987;18(5):919-23.
1987: Michael Chopp; M R Glasberg; J M Riddle; F W Hetzel; K M A Welch
Photodynamic therapy of normal cerebral tissue in the cat: a noninvasive model for cerebrovascular thrombosis.
Photochemistry and photobiology 1987;46(1):103-8.
1986: Paul D Stein; S Goldstein; Hani N Sabbah; Z Q Liu; Joseph A Helpern; James R Ewing; J B Lakier; Michael Chopp; W F LaPenna; K M A Welch
In vivo evaluation of intracellular pH and high-energy phosphate metabolites during regional myocardial ischemia in cats using 31P nuclear magnetic resonance.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1986;3(2):262-9.
1985: Michael Chopp; Joseph A Helpern; Stanley Frinak; F W Hetzel; James R Ewing; K M A Welch
In vivo 31-P NMR of photoactivated hematoporphyrin derivative in cat brain.
Medical physics 1985;12(2):256-8.
1985: H D Portnoy; Craig A Branch; Michael Chopp
The CSF pulse wave in hydrocephalus.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 1985;1(5):248-54.
1984: Michael Chopp; Joseph A Helpern; James R Ewing; K M A Welch
Anoxia followed by hyperoxia: in vivo 31-P NMR of cat brain.
Magnetic resonance imaging 1984;2(4):329-33.
1983: H D Portnoy; Michael Chopp; Craig A Branch
Hydraulic model of myogenic autoregulation and the cerebrovascular bed: the effects of altering systemic arterial pressure.
Neurosurgery 1983;13(5):482-98.
1983: Michael Chopp; H D Portnoy; Craig A Branch
Hydraulic model of the cerebrovascular bed: an aid to understanding the volume-pressure test.
Neurosurgery 1983;13(1):5-11.
1982: H D Portnoy; Michael Chopp; Craig A Branch; M B Shannon
Cerebrospinal fluid pulse waveform as an indicator of cerebral autoregulation.
Journal of neurosurgery 1982;56(5):666-78.
1981: H D Portnoy; Michael Chopp
Cerebrospinal fluid pulse wave form analysis during hypercapnia and hypoxia.
Neurosurgery 1981;9(1):14-27.
1981: Michael Chopp; L Ewald; M Hartson
The contribution of internal scatter to radiation dose during CT scan of the head.
Neuroradiology 1981;22(3):145-50.
1981: Craig A Branch; Michael Chopp; H D Portnoy
Fast Fourier transform of individual cerebrospinal fluid pulse waves.
Biomedical sciences instrumentation 1981;17():45.
1980: Michael Chopp; H D Portnoy
Systems analysis of intracranial pressure. Comparison with volume-pressure test and CSF-pulse amplitude analysis.
Journal of neurosurgery 1980;53(4):516-27.
1980: Michael Chopp; H D Portnoy
Analysis of intracranial pressure waveforms, comparison to the volume pressure test.
Biomedical sciences instrumentation 1980;16():149-58.
1980: Michael Chopp; H D Portnoy; R Schurig; P Croissant
Clinical dosimetry during cerebral arteriography.
Neuroradiology 1980;20(2):79-81.