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dermot cooper

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David A Macdougall; Sebastian Wachten; Antonio Ciruela; Andrea Sinz; dermot cooper
Separate elements within a single IQ-like motif in adenylyl cyclase type 8 impart ca2+/calmodulin binding and autoinhibition.
Tung-Chung Mou; Nanako Masada; dermot cooper; Stephen R Sprang
Structural basis for inhibition of mammalian adenylyl cyclase by calcium.
Agnes C L Martin; Debbie Willoughby; Antonio Ciruela; Laura-Jo Ayling; Mario Pagano; Sebastian Wachten; Anders Tengholm; dermot cooper
Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8.

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2009: David A Macdougall; Sebastian Wachten; Antonio Ciruela; Andrea Sinz; dermot cooper
Separate elements within a single IQ-like motif in adenylyl cyclase type 8 impart ca2+/calmodulin binding and autoinhibition.
The Journal of biological chemistry 2009;284(23):15573-88.
2009: Tung-Chung Mou; Nanako Masada; dermot cooper; Stephen R Sprang
Structural basis for inhibition of mammalian adenylyl cyclase by calcium.
Biochemistry 2009;48(15):3387-97.
2009: Agnes C L Martin; Debbie Willoughby; Antonio Ciruela; Laura-Jo Ayling; Mario Pagano; Sebastian Wachten; Anders Tengholm; dermot cooper
Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8.
Molecular pharmacology 2009;75(4):830-42.
2009: Mario Pagano; Michael A Clynes; Nanako Masada; Antonio Ciruela; Laura-Jo Ayling; Sebastian Wachten; dermot cooper
Insights into the residence in lipid rafts of adenylyl cyclase AC8 and its regulation by capacitative calcium entry.
American journal of physiology. Cell physiology 2009;296(3):C607-19.
2009: Nanako Masada; Antonio Ciruela; David A Macdougall; dermot cooper
Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles.
The Journal of biological chemistry 2009;284(7):4451-63.
2008: Tasmina A Goraya; Nanako Masada; Antonio Ciruela; Debbie Willoughby; Michael A Clynes; dermot cooper
Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+.
Cellular signalling 2008;20(2):359-74.
2008: Debbie Willoughby; dermot cooper
Live-cell imaging of cAMP dynamics.
Nature methods 2008;5(1):29-36.
2007: Debbie Willoughby; George S Baillie; Martin J Lynch; Antonio Ciruela; Miles D Houslay; dermot cooper
Dynamic regulation, desensitization, and cross-talk in discrete subcellular microdomains during beta2-adrenoceptor and prostanoid receptor cAMP signaling.
The Journal of biological chemistry 2007;282(47):34235-49.
2007: Debbie Willoughby; dermot cooper
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains.
Physiological reviews 2007;87(3):965-1010.
2006: Andrea L Bauman; Joseph Soughayer; Bao T Nguyen; Debbie Willoughby; Graeme Carnegie; Wei Wong; Naoto Hoshi; Lorene K Langeberg; dermot cooper; Carmen W Dessauer; John D Scott
Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes.
Molecular cell 2006;23(6):925-31.
2006: A C L Martin; dermot cooper
Layers of organization of cAMP microdomains in a simple cell.
Biochemical Society transactions 2006;34(Pt 4):480-3.
2006: D Willoughby; dermot cooper
Use of single-cell imaging techniques to assess the regulation of cAMP dynamics.
Biochemical Society transactions 2006;34(Pt 4):468-71.
2006: dermot cooper; Andrew J Crossthwaite
Higher-order organization and regulation of adenylyl cyclases.
Trends in pharmacological sciences 2006;27(8):426-31.
2006: Christian Ihling; Andreas Schmidt; Stefan Kalkhof; Daniela M Schulz; Christoph Stingl; Karl Mechtler; Michael Haack; Annette G Beck-Sickinger; dermot cooper; Andrea Sinz
Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex.
Journal of the American Society for Mass Spectrometry 2006;17(8):1100-13.
2006: Agnes C L Martin; dermot cooper
Capacitative and 1-oleyl-2-acetyl-sn-glycerol-activated Ca(2+) entry distinguished using adenylyl cyclase type 8.
Molecular pharmacology 2006;70(2):769-77.
2006: Rachel E Simpson; Antonio Ciruela; dermot cooper
The role of calmodulin recruitment in Ca2+ stimulation of adenylyl cyclase type 8.
The Journal of biological chemistry 2006;281(25):17379-89.
2006: Debbie Willoughby; Wei Wong; Jerome Schaack; John D Scott; dermot cooper
An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics.
The EMBO journal 2006;25(10):2051-61.
2006: Liliana R V Castro; Ignacio Verde; dermot cooper; Rodolphe Fischmeister
Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes.
Circulation 2006;113(18):2221-8.
2006: Francesca Rochais; Aniella Abi-Gerges; Kathleen Horner; Florence Lefebvre; dermot cooper; Marco Conti; Rodolphe Fischmeister; Grégoire Vandecasteele
A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes.
Circulation research 2006;98(8):1081-8.
2006: Debbie Willoughby; dermot cooper
Ca2+ stimulation of adenylyl cyclase generates dynamic oscillations in cyclic AMP.
Journal of cell science 2006;119(Pt 5):828-36.
2006: Andrew J Crossthwaite; Antonio Ciruela; Timothy F Rayner; dermot cooper
A direct interaction between the N terminus of adenylyl cyclase AC8 and the catalytic subunit of protein phosphatase 2A.
Molecular pharmacology 2006;69(2):608-17.
2005: dermot cooper
Compartmentalization of adenylate cyclase and cAMP signalling.
Biochemical Society transactions 2005;33(Pt 6):1319-22.
2005: Debbie Willoughby; Nanako Masada; Andrew J Crossthwaite; Antonio Ciruela; dermot cooper
Localized Na+/H+ exchanger 1 expression protects Ca2+-regulated adenylyl cyclases from changes in intracellular pH.
The Journal of biological chemistry 2005;280(35):30864-72.
2005: Tasmina A Goraya; dermot cooper
Ca2+-calmodulin-dependent phosphodiesterase (PDE1): current perspectives.
Cellular signalling 2005;17(7):789-97.
2005: Timothy J Burton; dermot cooper; Bryony Dunning-Davies; Dina Mansour; Nanako Masada; Douglas R Ferguson
Aldosterone stimulates active Na+ transport in rabbit urinary bladder by both genomic and non-genomic processes.
European journal of pharmacology 2005;510(3):181-6.
2005: Andrew J Crossthwaite; Thomas Seebacher; Nanako Masada; Antonio Ciruela; Kim Dufraux; Joachim E Schultz; dermot cooper
The cytosolic domains of Ca2+-sensitive adenylyl cyclases dictate their targeting to plasma membrane lipid rafts.
The Journal of biological chemistry 2005;280(8):6380-91.
2005: Andreas Schmidt; Stefan Kalkhof; Christian Ihling; dermot cooper; Andrea Sinz
Mapping protein interfaces by chemical cross-linking and Fourier transform ion cyclotron resonance mass spectrometry: application to a calmodulin / adenylyl cyclase 8 peptide complex.
European journal of mass spectrometry (Chichester, England) 2005;11(5):525-34.
2004: Francesca Rochais; Grégoire Vandecasteele; Florence Lefebvre; Lugnier Claire; Hazel Lum; Jean-Luc Mazet; dermot cooper; Rodolphe Fischmeister
Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.
The Journal of biological chemistry 2004;279(50):52095-105.
2004: Tasmina A Goraya; Nanako Masada; Antonio Ciruela; dermot cooper
Sustained entry of Ca2+ is required to activate Ca2+-calmodulin-dependent phosphodiesterase 1A.
The Journal of biological chemistry 2004;279(39):40494-504.
2003: dermot cooper
Regulation and organization of adenylyl cyclases and cAMP.
The Biochemical journal 2003;375(Pt 3):517-29.
2003: dermot cooper
Molecular and cellular requirements for the regulation of adenylate cyclases by calcium.
Biochemical Society transactions 2003;31(Pt 5):912-5.
2003: Judy R Creighton; Nanako Masada; dermot cooper; Troy Stevens
Coordinate regulation of membrane cAMP by Ca2+-inhibited adenylyl cyclase and phosphodiesterase activities.
American journal of physiology. Lung cellular and molecular physiology 2003;284(1):L100-7.
2002: Biao Hu; Hiroko Nakata; Chen Gu; Tonny de Beer; dermot cooper
A critical interplay between Ca2+ inhibition and activation by Mg2+ of AC5 revealed by mutants and chimeric constructs.
The Journal of biological chemistry 2002;277(36):33139-47.
2002: Donna L Cioffi; Timothy Moore; Jerry Schaack; Judy R Creighton; dermot cooper; Troy Stevens
Dominant regulation of interendothelial cell gap formation by calcium-inhibited type 6 adenylyl cyclase.
The Journal of cell biology 2002;157(7):1267-78.
2002: Karen E Smith; Chen Gu; Karen A Fagan; Biao Hu; dermot cooper
Residence of adenylyl cyclase type 8 in caveolae is necessary but not sufficient for regulation by capacitative Ca(2+) entry.
The Journal of biological chemistry 2002;277(8):6025-31.
2002: Chen Gu; James J Cali; dermot cooper
Dimerization of mammalian adenylate cyclases.
European journal of biochemistry / FEBS 2002;269(2):413-21.
2001: Thomas C Rich; Karen A Fagan; T E Tse; Jerome Schaack; dermot cooper; Jeffrey W Karpen
A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13049-54.
2000: Karen A Fagan; R A Graf; S Tolman; Jerome Schaack; dermot cooper
Regulation of a Ca2+-sensitive adenylyl cyclase in an excitable cell. Role of voltage-gated versus capacitative Ca2+ entry.
The Journal of biological chemistry 2000;275(51):40187-94.
2000: Karen A Fagan; Karen E Smith; dermot cooper
Regulation of the Ca2+-inhibitable adenylyl cyclase type VI by capacitative Ca2+ entry requires localization in cholesterol-rich domains.
The Journal of biological chemistry 2000;275(34):26530-7.
2000: Thomas C Rich; Karen A Fagan; H Nakata; Jerome Schaack; dermot cooper; Jeffrey W Karpen
Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion.
The Journal of general physiology 2000;116(2):147-61.
2000: M P Wong; dermot cooper; K W Young; J M Young
Characteristics of the Ca(2+)-dependent inhibition of cyclic AMP accumulation by histamine and thapsigargin in human U373 MG astrocytoma cells.
British journal of pharmacology 2000;130(5):1021-30.
2000: S Lin; Karen A Fagan; Kai-Xun Li; P W Shaul; dermot cooper; David M Rodman
Sustained endothelial nitric-oxide synthase activation requires capacitative Ca2+ entry.
The Journal of biological chemistry 2000;275(24):17979-85.
2000: Chen Gu; dermot cooper
Ca(2+), Sr(2+), and Ba(2+) identify distinct regulatory sites on adenylyl cyclase (AC) types VI and VIII and consolidate the apposition of capacitative cation entry channels and Ca(2+)-sensitive ACs.
The Journal of biological chemistry 2000;275(10):6980-6.
1999: jean-louis guillou; H Nakata; dermot cooper
Inhibition by calcium of mammalian adenylyl cyclases.
The Journal of biological chemistry 1999;274(50):35539-45.
1999: jean-louis guillou; Gregory M Rose; dermot cooper
Differential activation of adenylyl cyclases by spatial and procedural learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(14):6183-90.
1999: Karen A Fagan; Thomas C Rich; S Tolman; Jerome Schaack; Jeffrey W Karpen; dermot cooper
Adenovirus-mediated expression of an olfactory cyclic nucleotide-gated channel regulates the endogenous Ca2+-inhibitable adenylyl cyclase in C6-2B glioma cells.
The Journal of biological chemistry 1999;274(18):12445-53.
1999: Chen Gu; dermot cooper
Calmodulin-binding sites on adenylyl cyclase type VIII.
The Journal of biological chemistry 1999;274(12):8012-21.
1998: dermot cooper; Michael J Schell; peter thorn; Robin F Irvine
Regulation of adenylyl cyclase by membrane potential.
The Journal of biological chemistry 1998;273(42):27703-7.
1998: Karen A Fagan; NE Mons; dermot cooper
Dependence of the Ca2+-inhibitable adenylyl cyclase of C6-2B glioma cells on capacitative Ca2+ entry.
The Journal of biological chemistry 1998;273(15):9297-305.
1998: Nicole Mons; Laurence Decorte; Robert Jaffard; dermot cooper
Ca2+-sensitive adenylyl cyclases, key integrators of cellular signalling.
Life sciences 1998;62(17-18):1647-52.
1998: dermot cooper; Jeffrey W Karpen; Karen A Fagan; NE Mons
Ca(2+)-sensitive adenylyl cyclases.
Advances in second messenger and phosphoprotein research 1998;32():23-51.
1997: Y Nakahashi; E Nelson; Karen A Fagan; E Gonzales; jean-louis guillou; dermot cooper
Construction of a full-length Ca2+-sensitive adenylyl cyclase/aequorin chimera.
The Journal of biological chemistry 1997;272(29):18093-7.
1996: Karen A Fagan; R Mahey; dermot cooper
Functional co-localization of transfected Ca(2+)-stimulable adenylyl cyclases with capacitative Ca2+ entry sites.
The Journal of biological chemistry 1996;271(21):12438-44.
1995: N Mons; A Harry; P Dubourg; R T Premont; Ravi Iyengar; dermot cooper
Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8473-7.
1995: K Hellevuo; M Yoshimura; N Mons; Paula L Hoffman; dermot cooper; Boris Tabakoff
The characterization of a novel human adenylyl cyclase which is present in brain and other tissues.
The Journal of biological chemistry 1995;270(19):11581-9.
1995: dermot cooper; N Mons; Jeffrey W Karpen
Adenylyl cyclases and the interaction between calcium and cAMP signalling.
Nature 1995;374(6521):421-4.
1995: Troy Stevens; Y Nakahashi; D N Cornfield; Ivan F McMurtry; dermot cooper; David M Rodman
Ca(2+)-inhibitable adenylyl cyclase modulates pulmonary artery endothelial cell cAMP content and barrier function.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2696-700.
1995: M Chiono; R Mahey; G Tate; dermot cooper
Capacitative Ca2+ entry exclusively inhibits cAMP synthesis in C6-2B glioma cells. Evidence that physiologically evoked Ca2+ entry regulates Ca(2+)-inhibitable adenylyl cyclase in non-excitable cells.
The Journal of biological chemistry 1995;270(3):1149-55.
1994: N Mons; dermot cooper
Adenylyl cyclase mRNA expression does not reflect the predominant Ca2+/calmodulin-stimulated activity in the hypothalamus.
Journal of neuroendocrinology 1994;6(6):665-71.
1994: dermot cooper; N Mons; Karen A Fagan
Ca(2+)-sensitive adenylyl cyclases.
Cellular signalling 1994;6(8):823-40.
1994: J J Cali; J C Zwaagstra; N Mons; dermot cooper; J Krupinski
Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain.
The Journal of biological chemistry 1994;269(16):12190-5.
1994: N Mons; dermot cooper
Selective expression of one Ca(2+)-inhibitable adenylyl cyclase in dopaminergically innervated rat brain regions.
Brain research. Molecular brain research 1994;22(1-4):236-44.
1994: dermot cooper; M Yoshimura; Y Zhang; M Chiono; R Mahey
Capacitative Ca2+ entry regulates Ca(2+)-sensitive adenylyl cyclases.
The Biochemical journal 1994;297 ( Pt 3)():437-40.
1994: dermot cooper
Regulation of Ca(2+)-sensitive adenylyl cyclases by calcium ion in vitro and in vivo.
Methods in enzymology 1994;238():71-81.
1993: M A Debernardi; R Munshi; M Yoshimura; dermot cooper; Gary Brooker
Predominant expression of type-VI adenylate cyclase in C6-2B rat glioma cells may account for inhibition of cyclic AMP accumulation by calcium.
The Biochemical journal 1993;293 ( Pt 2)():325-8.
1993: N Mons; M Yoshimura; dermot cooper
Discrete expression of Ca2+/calmodulin-sensitive and Ca(2+)-insensitive adenylyl cyclases in the rat brain.
Synapse (New York, N.Y.) 1993;14(1):51-9.
1993: K Hellevuo; M Yoshimura; M Kao; Paula L Hoffman; dermot cooper; Boris Tabakoff
A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.
Biochemical and biophysical research communications 1993;192(1):311-8.
1993: M Yoshimura; dermot cooper
Type-specific stimulation of adenylylcyclase by protein kinase C.
The Journal of biological chemistry 1993;268(7):4604-7.
1993: dermot cooper; G Brooker
Ca(2+)-inhibited adenylyl cyclase in cardiac tissue.
Trends in pharmacological sciences 1993;14(2):34-6.
1992: A Garritsen; Y Zhang; J A Firestone; Michael D Browning; dermot cooper
Inhibition of cyclic AMP accumulation in intact NCB-20 cells as a direct result of elevation of cytosolic Ca2+.
Journal of neurochemistry 1992;59(5):1630-9.
1992: M Yoshimura; dermot cooper
Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):6716-20.
1992: A Garritsen; dermot cooper
Manipulation of intracellular calcium in NCB-20 cells.
Journal of neurochemistry 1992;59(1):190-9.
1992: P Mollard; Y Zhang; D Rodman; dermot cooper
Limited accumulation of cyclic AMP underlies a modest vasoactive-intestinal-peptide-mediated increase in cytosolic [Ca2+] transients in GH3 pituitary cells.
The Biochemical journal 1992;284 ( Pt 3)():637-40.
1992: A Garritsen; Y Zhang; dermot cooper
Purinergic receptor regulation of signal transduction in NCB-20 cells.
Molecular pharmacology 1992;41(4):743-9.
1992: K K Caldwell; C L Boyajian; dermot cooper
The effects of Ca2+ and calmodulin on adenylyl cyclase activity in plasma membranes derived from neural and non-neural cells.
Cell calcium 1992;13(2):107-21.
1991: dermot cooper
Inhibition of adenylate cyclase by Ca(2+)--a counterpart to stimulation by Ca2+/calmodulin.
The Biochemical journal 1991;278 ( Pt 3)():903-4.
1991: P Mollard; N Guérineau; Carlo Chiavaroli; Werner Schlegel; dermot cooper
Adenosine A1 receptor-induced inhibition of Ca2+ transients linked to action potentials in clonal pituitary cells.
European journal of pharmacology 1991;206(4):271-7.
1991: C L Boyajian; A Garritsen; dermot cooper
Bradykinin stimulates Ca2+ mobilization in NCB-20 cells leading to direct inhibition of adenylylcyclase. A novel mechanism for inhibition of cAMP production.
The Journal of biological chemistry 1991;266(8):4995-5003.
1991: A Garritsen; dermot cooper
Evaluation of the role of GTP hydrolysis in the interaction between Mg2+ and GTP in regulating agonist binding to the adenosine A1 receptor.
Journal of receptor research 1991;11(5):849-64.
1990: P Bickford-Wimer; M Kim; C Boyajian; dermot cooper; Robert Freedman
Effects of pertussis toxin on caudate neuron electrophysiology: studies with dopamine D1 and D2 agonists.
Brain research 1990;533(2):263-7.
1990: dermot cooper; C L Boyajian; Paul K Goldsmith; C G Unson; Allen Spiegel
Differential expression of low molecular weight form of Gs-alpha in neostriatum and cerebellum: correlation with expression of calmodulin-independent adenylyl cyclase.
Brain research 1990;523(1):143-6.
1990: C L Boyajian; dermot cooper
Potent and cooperative feedback inhibition of adenylate cyclase activity by calcium in pituitary-derived GH3 cells.
Cell calcium 1990;11(4):299-307.
1989: C L Boyajian; P Bickford-Wimer; M B Kim; Robert Freedman; dermot cooper
Pertussis toxin lesioning of the nucleus caudate-putamen attenuates adenylate cyclase inhibition and alters neuronal electrophysiological activity.
Brain research 1989;495(1):66-74.
1989: S M Helmke; dermot cooper
Solubilization of stable adenosine A1 receptors from rat brain.
The Biochemical journal 1989;257(2):413-8.
1989: dermot cooper; K K Caldwell; C L Boyajian; D W Petcoff; W Schlegel
Adenosine A1 receptors inhibit both adenylate cyclase activity and TRH-activated Ca2+ channels by a pertussis toxin-sensitive mechanism in GH3 cells.
Cellular signalling 1989;1(1):85-97.
1988: M K Ahlijanian; dermot cooper
Distinct interactions between Ca2+/calmodulin and neurotransmitter stimulation of adenylate cyclase in striatum and hippocampus.
Cellular and molecular neurobiology 1988;8(4):459-69.
1988: K K Caldwell; M K Newell; J C Cambier; Kedar Prasad; J M Masserano; W Schlegel; dermot cooper
Evaluation of methods for the isolation of plasma membranes displaying guanosine 5'-triphosphate-dependence for the regulation of adenylate cyclase activity: potential application to the study of other guanosine 5'-triphosphate-dependent transduction systems.
Analytical biochemistry 1988;175(1):177-90.
1988: dermot cooper; K K Caldwell
Does calmodulin regulate non-neuronal adenylate cyclase?
The Biochemical journal 1988;254(3):935-6.
1988: dermot cooper; M K Ahlijanian; Edward Perez-Reyes
Calmodulin plays a dominant role in determining neurotransmitter regulation of neuronal adenylate cyclase.
Journal of cellular biochemistry 1988;36(4):417-27.
1988: dermot cooper; K K Caldwell; Edward Perez-Reyes; M K Ahlijanian; W Schlegel
Interactions between neurotransmitters that regulate cAMP and intracellular Ca2+ levels in the CNS.
Advances in experimental medicine and biology 1988;236():217-27.
1987: S M Yeung; Edward Perez-Reyes; dermot cooper
Hydrodynamic properties of adenosine Ri receptors solubilized from rat cerebral-cortical membranes.
The Biochemical journal 1987;248(3):635-42.
1987: M K Ahlijanian; M K Halford; dermot cooper
Ca2+/calmodulin distinguishes between guanyl-5'-yl-imidodiphosphate- and opiate-mediated inhibition of rat striatal adenylate cyclase.
Journal of neurochemistry 1987;49(4):1308-15.
1987: Edward Perez-Reyes; dermot cooper
Calmodulin stimulation of the rat cerebral cortical adenylate cyclase is required for the detection of guanine nucleotide- or hormone-mediated inhibition.
Molecular pharmacology 1987;32(1):212-6.
1987: M K Ahlijanian; dermot cooper
Calmodulin may play a pivotal role in neurotransmitter-mediated inhibition and stimulation of rat cerebellar adenylate cyclase.
Molecular pharmacology 1987;32(1):127-32.
1987: D W Petcoff; dermot cooper
Adenosine receptor agonists inhibit inositol phosphate accumulation in rat striatal slices.
European journal of pharmacology 1987;137(2-3):269-71.
1987: M K Ahlijanian; dermot cooper
Antagonism of calmodulin-stimulated adenylate cyclase by trifluoperazine, calmidazolium and W-7 in rat cerebellar membranes.
The Journal of pharmacology and experimental therapeutics 1987;241(2):407-14.
1986: Edward Perez-Reyes; dermot cooper
Interaction of the inhibitory GTP regulatory component with soluble cerebral cortical adenylate cyclase.
Journal of neurochemistry 1986;46(5):1508-16.
1986: L T Frame; S M Yeung; J C Venter; dermot cooper
Target size of the adenosine Ri receptor.
The Biochemical journal 1986;235(2):621-4.
1986: dermot cooper; C M Bier-Laning; M K Halford; M K Ahlijanian; Nancy R Zahniser
Dopamine, acting through D-2 receptors, inhibits rat striatal adenylate cyclase by a GTP-dependent process.
Molecular pharmacology 1986;29(2):113-9.
1986: dermot cooper
Guanine nucleotide regulatory proteins and signal transduction in the CNS--multiple mechanisms.
Clinical neuropharmacology 1986;9 Suppl 4():6-8.
1985: J R Owens; L T Frame; M Ui; dermot cooper
Cholera toxin ADP-ribosylates the islet-activating protein substrate in adipocyte membranes and alters its function.
The Journal of biological chemistry 1985;260(29):15946-52.
1985: S M Yeung; L H Fossom; Donald L Gill; dermot cooper
Magnesium ion exerts a central role in the regulation of inhibitory adenosine receptors.
The Biochemical journal 1985;229(1):91-100.
1985: dermot cooper; S M Yeung; Edward Perez-Reyes; J R Owens; L H Fossom; Donald L Gill
Properties required of a functional Ni, the GTP regulatory complex that mediates the inhibitory actions of neurotransmitters on adenylate cyclase.
Advances in cyclic nucleotide and protein phosphorylation research 1985;19():75-86.
1984: dermot cooper; S M Yeung; Edward Perez-Reyes; L H Fossom
A central role for magnesium in the regulation of inhibitory adenosine receptors.
Advances in experimental medicine and biology 1984;175():17-30.
1983: J M Girardot; J Kempf; dermot cooper
Role of calmodulin in the effect of guanyl nucleotides on rat hippocampal adenylate cyclase: involvement of adenosine and opiates.
Journal of neurochemistry 1983;41(3):848-59.
1982: dermot cooper; R Jagus
Impaired adenylate cyclase activity of phenylhydrazine-induced reticulocytes.
The Journal of biological chemistry 1982;257(9):4684-7.
1982: dermot cooper; C Londos; Donald L Gill; Martin Rodbell
Opiate receptor-mediated inhibition of adenylate cyclase in rat striatal plasma membranes.
Journal of neurochemistry 1982;38(4):1164-7.
1982: J I Davies; dermot cooper; D Everett
Analysis of apparent co-operativity in the catecholamine-stimulated lipolysis of rat adipose tissue.
Biochemical pharmacology 1982;31(5):737-43.
1982: J I Davies; dermot cooper; D Everett
Catecholamines and the kinetics of lipolysis in isolated rat adipocytes. Statistical analysis and handling of day-to-day variability in dose-response curves: a general procedure for assessing and manipulating dose-response data.
Biochemical pharmacology 1982;31(5):711-9.
1982: dermot cooper; J I Davies
A kinetic analysis of the actions of L-noradrenaline and its related agonists and antagonists on in vitro lipolysis in rat adipose tissue.
Biochemical pharmacology 1982;31(5):721-35.
1982: dermot cooper
Bimodal regulation of adenylate cyclase.
FEBS letters 1982;138(2):157-63.
1982: dermot cooper; C Londos
GTP-dependent stimulation and inhibition of adenylate cyclase.
Horizons in biochemistry and biophysics 1982;6():309-33.
1981: dermot cooper; R Jagus; R L Somers; Martin Rodbell
Cholera toxin modifies diverse GTP-modulated regulatory proteins.
Biochemical and biophysical research communications 1981;101(4):1179-85.
1981: Martin Rodbell; P M Lad; T B Nielsen; dermot cooper; W Schlegel; M. Sue Preston; C Londos; E S Kempner
The structure of adenylate cyclase systems.
Advances in cyclic nucleotide research 1981;14():3-14.
1981: J Wolff; C Londos; dermot cooper
Adenosine receptors and the regulation of adenylate cyclase.
Advances in cyclic nucleotide research 1981;14():199-214.
1981: C Londos; dermot cooper; Martin Rodbell
Receptor-mediated stimulation and inhibition of adenylate cyclases: the fat cell as a model system.
Advances in cyclic nucleotide research 1981;14():163-71.
1980: dermot cooper; C Londos; Martin Rodbell
Adenosine receptor-mediated inhibition of rat cerebral cortical adenylate cyclase by a GTP-dependent process.
Molecular pharmacology 1980;18(3):598-601.
1980: M C Lin; dermot cooper; Martin Rodbell
Selective effects of organic mercurials on the GTP-regulatory proteins of adenylate cyclase systems.
The Journal of biological chemistry 1980;255(15):7250-4.
1980: W Schlegel; dermot cooper; Martin Rodbell
Inhibition and activation of fat cell adenylate cyclase by GTP is mediated by structures of different size.
Archives of biochemistry and biophysics 1980;201(2):678-82.
1980: C Londos; dermot cooper; J Wolff
Subclasses of external adenosine receptors.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(5):2551-4.
1979: dermot cooper; W Schlegel; M C Lin; Martin Rodbell
The fat cell adenylate cyclase system. Characterization and manipulation of its bimodal regulation by GTP.
The Journal of biological chemistry 1979;254(18):8927-31.
1979: P Glynn; dermot cooper; D Schulster
The regulation of adenylate cyclase of the adrenal cortex.
Molecular and cellular endocrinology 1979;13(2):99-121.
1979: dermot cooper; C Londos
Evaluation of the effects of adenosine on hepatic and adipocyte adenylate cyclase under conditions where adenosine is not generated endogenously.
Journal of cyclic nucleotide research 1979;5(4):289-302.
1978: C Londos; dermot cooper; W Schlegel; Martin Rodbell
Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(11):5362-6.
1978: P Glynn; dermot cooper
Inhibition of bovine adrenocortical adenylate cyclase activity by adenosine.
Biochimica et biophysica acta 1978;526(2):605-12.
1978: P Glynn; dermot cooper; D Schulster
Activation of adenylate cyclase in bovine adrenal cortex membranes by magnesium ions, guanine nucleotides and corticotropin.
Biochimica et biophysica acta 1978;524(2):474-83.
1977: P Glynn; dermot cooper; D Schulster
Modulation of the response of bovine adrenocortical adenylate cyclase to corticotropin.
The Biochemical journal 1977;168(2):277-82.
1977: P Glynn; dermot cooper; D Schulster
Control of bovine adrenocortical adenylate cyclase activity by guanine neucleotides [proceedings].
Biochemical Society transactions 1977;5(4):973-5.
1977: dermot cooper; D Schulster
Apparent positive cooperativity of ACTH action on adrenocortical cells: the effect of hormone degradation.
Molecular and cellular endocrinology 1977;6(3):211-6.
1971: dermot cooper; W K Downey
Lipase activity of bovine mammary gland.
The Biochemical journal 1971;125(4):95P-96P.