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Wei Huang

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Publications

TOP 3
Helen Wang; Aditi Banerjee; Wei Huang; Jared Orwenyo; Gerardo Vasta; Lai-Xi Wang
Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3.
Rui Jiang; Anatoly B Kolomeisky; Yu-Qing Wang; Mao-Bin Hu; Wei Huang; Qing-Song Wu
Phase diagram structures in a periodic one-dimensional exclusion process.
Wei Huang; Christian Toonstra; Shu-Quan Fan; John Giddens; Lai-Xi Wang
Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.

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All Publications

2013: Helen Wang; Aditi Banerjee; Wei Huang; Jared Orwenyo; Gerardo Vasta; Lai-Xi Wang
Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3.
Bioorganic & medicinal chemistry 2013;21(7):2037-44.
2013: Rui Jiang; Anatoly B Kolomeisky; Yu-Qing Wang; Mao-Bin Hu; Wei Huang; Qing-Song Wu
Phase diagram structures in a periodic one-dimensional exclusion process.
Physical review. E, Statistical, nonlinear, and soft matter physics 2013;87(1):012107.
2012: Wei Huang; Christian Toonstra; Shu-Quan Fan; John Giddens; Lai-Xi Wang
Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.
Journal of the American Chemical Society 2012;134(29):12308-18.
2012: Alan S Cross; Chiguang Feng; Sergei Atamas; Wei Guang; Wei Huang; Sang Won Hyun; Erik Lillehoj; Anguo Liu; Irina G Luzina; Alba Miranda-Ribera; Chinh Nguyen; Antonino Passaniti; Adam C Puché; William S Twaddell; Lai-Xi Wang; Lei Zhang; Simeon E Goldblum
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
The Journal of biological chemistry 2012;287(19):15966-80.
2012: Shu-Quan Fan; Wei Huang; Lai-Xi Wang
Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae.
The Journal of biological chemistry 2012;287(14):11272-81.
2011: Guozhang Zou; QIANG YANG; Wei Huang; Cishan Li; Hirofumi Ochiai; Lai-Xi Wang
Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.
Journal of the American Chemical Society 2011;133(46):18975-91.
2011: Mohammed N Amin; Wei Huang; Rahman M Mizanur; Lai-Xi Wang
Convergent synthesis of homogeneous Glc1Man9GlcNAc2-protein and derivatives as ligands of molecular chaperones in protein quality control.
Journal of the American Chemical Society 2011;133(36):14404-17.
2011: Evelien M Bunnik; Eoin Coakley; Winnie Dong; Diana Edo-Matas; Arne Frantzell; P Richard Harrigan; Wei Huang; Christos J Petropoulos; Hanneke Schuitemaker; Luke C Swenson; Angélique B van 't Wout
Detection of inferred CCR5- and CXCR4-using HIV-1 variants and evolutionary intermediates using ultra-deep pyrosequencing.
PLoS pathogens 2011;7(6):e1002106.
2011: Wei Huang; Jie Li; Lai-Xi Wang
Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptides.
Chembiochem : a European journal of chemical biology 2011;12(6):932-41.
2010: Wei Huang; Xinyu Zhang; Tongzhong Ju; Richard D Cummings; Lai-Xi Wang
Expeditious chemoenzymatic synthesis of CD52 glycopeptide antigens.
Organic & biomolecular chemistry 2010;8(22):5224-33.
2010: Midori Umekawa; Takayuki Higashiyama; Yurie Koga; Tomonari Tanaka; Masato Noguchi; Atsushi Kobayashi; Shin-Ichiro Shoda; Wei Huang; Lai-Xi Wang; Hisashi Ashida; Kenji Yamamoto
Efficient transfer of sialo-oligosaccharide onto proteins by combined use of a glycosynthase-like mutant of Mucor hiemalis endoglycosidase and synthetic sialo-complex-type sugar oxazoline.
Biochimica et biophysica acta 2010;1800(11):1203-9.
2010: Wei Huang; QIANG YANG; Midori Umekawa; Kenji Yamamoto; Lai-Xi Wang
Arthrobacter endo-beta-N-acetylglucosaminidase shows transglycosylation activity on complex-type N-glycan oxazolines: one-pot conversion of ribonuclease B to sialylated ribonuclease C.
Chembiochem : a European journal of chemical biology 2010;11(10):1350-5.
2010: Ya-Wen Chen; Ming-Shyue Lee; Amanda Lucht; Feng-Pai Chou; Wei Huang; Thomas C Havighurst; KyungMann Kim; Jehng-Kang Wang; Toni M Antalis; Michael D Johnson; Chen-Yong Lin
TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells.
The American journal of pathology 2010;176(6):2986-96.
2010: QIANG YANG; Cishan Li; Yadong Wei; Wei Huang; Lai-Xi Wang
Expression, glycoform characterization, and antibody-binding of HIV-1 V3 glycopeptide domain fused with human IgG1-Fc.
Bioconjugate chemistry 2010;21(5):875-83.
2010: Flavio Schwarz; Wei Huang; Cishan Li; Benjamin L Schulz; Christian Lizak; Alessandro Palumbo; Shin Numao; Dario Neri; Markus Aebi; Lai-Xi Wang
A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation.
Nature chemical biology 2010;6(4):264-6.
2010: Midori Umekawa; Cishan Li; Takayuki Higashiyama; Wei Huang; Hisashi Ashida; Kenji Yamamoto; Lai-Xi Wang
Efficient glycosynthase mutant derived from Mucor hiemalis endo-beta-N-acetylglucosaminidase capable of transferring oligosaccharide from both sugar oxazoline and natural N-glycan.
The Journal of biological chemistry 2010;285(1):511-21.
2009: Wei Huang; Denong Wang; Masao Yamada; Lai-Xi Wang
Chemoenzymatic synthesis and lectin array characterization of a class of N-glycan clusters.
Journal of the American Chemical Society 2009;131(49):17963-71.
2009: Lai-Xi Wang; Wei Huang
Enzymatic transglycosylation for glycoconjugate synthesis.
Current opinion in chemical biology 2009;13(5-6):592-600.
2009: Jianli Chen; Wei Huang; Gaoyan Lian; Feng Lin
The efficient total synthesis of bis-glycosyl apigenin from naringenin: a greener way.
Carbohydrate research 2009;344(16):2245-9.
2009: Wei Huang; Stan Groothuys; Alonso Heredia; Brian H M Kuijpers; Floris P J T Rutjes; Floris L van Delft; Lai-Xi Wang
Enzymatic glycosylation of triazole-linked GlcNAc/Glc-peptides: synthesis, stability and anti-HIV activity of triazole-linked HIV-1 gp41 glycopeptide C34 analogues.
Chembiochem : a European journal of chemical biology 2009;10(7):1234-42.
2009: Robert J Luallen; Hu Fu; Caroline Agrawal-Gamse; Innocent Mboudjeka; Wei Huang; Fang-Hua Lee; Lai-Xi Wang; Robert W Doms; Yu Geng
A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.
Journal of virology 2009;83(10):4861-70.
2009: Hirofumi Ochiai; Wei Huang; Lai-Xi Wang
Endo-beta-N-acetylglucosaminidase-catalyzed polymerization of beta-Glcp-(1-->4)-GlcpNAc oxazoline: a revisit to enzymatic transglycosylation.
Carbohydrate research 2009;344(5):592-8.
2009: Wei Huang; Cishan Li; Bing Li; Midori Umekawa; Kenji Yamamoto; Xinyu Zhang; Lai-Xi Wang
Glycosynthases enable a highly efficient chemoenzymatic synthesis of N-glycoproteins carrying intact natural N-glycans.
Journal of the American Chemical Society 2009;131(6):2214-23.
2008: Wei Huang; Hirofumi Ochiai; Xinyu Zhang; Lai-Xi Wang
Introducing N-glycans into natural products through a chemoenzymatic approach.
Carbohydrate research 2008;343(17):2903-13.
2008: Hirofumi Ochiai; Wei Huang; Lai-Xi Wang
Expeditious chemoenzymatic synthesis of homogeneous N-glycoproteins carrying defined oligosaccharide ligands.
Journal of the American Chemical Society 2008;130(41):13790-803.
2008: Yadong Wei; Cishan Li; Wei Huang; Bing Li; Scott E Strome; Lai-Xi Wang
Glycoengineering of human IgG1-Fc through combined yeast expression and in vitro chemoenzymatic glycosylation.
Biochemistry 2008;47(39):10294-304.
2008: Cishan Li; Wei Huang; Lai-Xi Wang
Chemoenzymatic synthesis of N-linked neoglycoproteins through a chitinase-catalyzed transglycosylation.
Bioorganic & medicinal chemistry 2008;16(18):8366-72.
2008: Midori Umekawa; Wei Huang; Bing Li; Kiyotaka Fujita; Hisashi Ashida; Lai-Xi Wang; Kenji Yamamoto
Mutants of Mucor hiemalis endo-beta-N-acetylglucosaminidase show enhanced transglycosylation and glycosynthase-like activities.
The Journal of biological chemistry 2008;283(8):4469-79.
2007: Weiqun Shen; CHAO XU; Wei Huang; Jiahai Zhang; Justin E Carlson; Xiaoming Tu; Jihui Wu; Yunyu Shi
Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails.
Biochemistry 2007;46(8):2100-10.
2006: Haiming Dai; Wei Huang; Jian Xu; Bo Yao; Shangmin Xiong; Husheng Ding; Yajun Tang; Haiyan Liu; Jihui Wu; Yunyu Shi
Binding model of human coactosin-like protein with filament actin revealed by mutagenesis.
Biochimica et biophysica acta 2006;1764(11):1688-700.
2006: Donna M Muzny; Steven E Scherer; Rajinder Kaul; Jing Wang; Jun Yu; Ralf Sudbrak; Christian J Buhay; Rui Chen; Andrew Cree; Yan Ding; Shannon Dugan-Rocha; Rachel Gill; Preethi Gunaratne; Ronald Harris; Alicia C Hawes; Judith Hernandez; Anne V Hodgson; Jennifer Hume; Andrew Jackson; Ziad Mohid Khan; Christie Kovar-Smith; Lora R Lewis; Ryan J Lozado; Michael L Metzker; Aleksandar Milosavljevic; George R Miner; Margaret B Morgan; Lynne V Nazareth; Graham Scott; Erica Sodergren; Xing-Zhi Song; David Steffen; Sharon Wei; David A Wheeler; Mathew W Wright; Kim C Worley; Ye Yuan; Zhengdong D Zhang; Charles Q Adams; M Ali Ansari-Lari; Mulu Ayele; Mary J Brown; Guan Chen; Zhijian Chen; James Clendenning; Kerstin P Clerc-Blankenburg; Runsheng Chen; Zhu Chen; Clay Davis; Oliver Delgado; Huyen H Dinh; Wei Dong; Heather Draper; Stephen Ernst; Gang Fu; Manuel Gonzalez-Garay; Dawn K Garcia; Will Gillett; Jun Gu; Bailin Hao; Eric Haugen; Paul Havlak; Xin He; Steffen Hennig; Songnian Hu; Wei Huang; Laronda R Jackson; Leni S Jacob; Susan H Kelly; Michael Kube; Ruth Levy; Zhangwan Li; Bin Liu; Jing Liu; Wen Liu; Jing Lu; Manjula Maheshwari; Bao-Viet Nguyen; Geoffrey O Okwuonu; Anthony Palmeiri; Shiran Pasternak; Lesette M Perez; Karen A Phelps; Farah J H Plopper; Boqin Qiang; Christopher Raymond; Ruben Rodriguez; Channakhone Saenphimmachak; Jireh Santibanez; Hua Shen; Yan Shen; Sandhya Subramanian; Paul E Tabor; Daniel Verduzco; Lenee Waldron; Jian Wang; Jun Wang; Qiaoyan Wang; Gabrielle A Williams; Gane K-S Wong; Zhijian Yao; JingKun Zhang; Xiuqing Zhang; Guoping Zhao; Jianling Zhou; Yang Zhou; David Nelson; Hans Lehrach; Richard Reinhardt; Susan Naylor; Huanming Yang; Maynard Olson; George Weinstock; Richard A Gibbs
The DNA sequence, annotation and analysis of human chromosome 3.
Nature 2006;440(7088):1194-8.
2005: Eric S Daar; Henry S Lynn; Sharyne Donfield; Alice Lail; Stephen J O'Brien; Wei Huang; Cheryl A Winkler
Stromal cell-derived factor-1 genotype, coreceptor tropism, and HIV type 1 disease progression.
The Journal of infectious diseases 2005;192(9):1597-605.
2005: Wei Huang; Roman Osman; Marvin C Gershengorn
Agonist-induced conformational changes in thyrotropin-releasing hormone receptor type I: disulfide cross-linking and molecular modeling approaches.
Biochemistry 2005;44(7):2419-31.
2003: Michael Bates; Terri Wrin; Wei Huang; Christos J Petropoulos; Nicholas S Hellmann
Practical applications of viral fitness in clinical practice.
Current opinion in infectious diseases 2003;16(1):11-8.
2003: Wei Huang; Andrea V Gamarnik; Kay Limoli; Christos J Petropoulos; Jeannette M Whitcomb
Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication.
Journal of virology 2003;77(2):1512-23.
2002: Jeannette M Whitcomb; Wei Huang; Kay Limoli; Ellen Paxinos; Terri Wrin; Gail Skowron; Steven G Deeks; Michael Bates; Nicholas S Hellmann; Christos J Petropoulos
Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV-1: clinical, phenotypic and genotypic correlates.
AIDS (London, England) 2002;16(15):F41-7.
2002: Tian-Hong Wang; Zhi-Hong Wu; Shi-Li Liu; Wei Huang
Cloning and sequence analysis of a mitochondrial gene cluster encoding cytochrome C oxidase subunit III from Trichoderma pseudokoningii.
DNA sequence : the journal of DNA sequencing and mapping 2002;13(5):271-5.
2002: Gregory S Hamilton; Yong-Qian Wu; David C Limburg; Douglas E Wilkinson; Mark Vaal; Jia-He Li; Christine Thomas; Wei Huang; Hansjorg Sauer; Douglas T Ross; Raj Soni; Yi Chen; Hongshi Guo; Pamela Howorth; Heather Valentine; Shi Liang; Dawn Spicer; Mike Fuller; Joseph P Steiner
Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.
Journal of medicinal chemistry 2002;45(16):3549-57.
2000: Christos J Petropoulos; Neil Parkin; Kay Limoli; Yolanda Lie; Terri Wrin; Wei Huang; H Tian; D Smith; G A Winslow; D J Capon; Jeannette M Whitcomb
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy 2000;44(4):920-8.
1996: J Hirsch; Wei Huang; A G Kalivretenos
Tetrameric peptide bundles via a highly convergent synthesis.
Biopolymers 1996;39(6):761-3.