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Luc Bijnens

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An Van den Bergh; Koen Wuyts; Luc Bijnens; Ron A H J Gilissen; Denise Morrison; Vikash Sinha; Roel Straetemans; Claire Mackie
Prediction of human oral plasma concentration-time profiles using preclinical data: comparative evaluation of prediction approaches in early pharmaceutical discovery.
Willem Talloen; Sepp Hochreiter; Luc Bijnens; Adetayo Kasim; Ziv Shkedy; Dhammika Amaratunga; Hinrich Göhlmann
Filtering data from high-throughput experiments based on measurement reliability.
Kristien Wouters; Jose Cortinas Abrahantes; Geert Molenberghs; Helena Geys; Abdellah Ahnaou; Wilhelmus H I M Drinkenburg; Luc Bijnens
Correction for model selection bias using a modified model averaging approach for supervised learning methods applied to EEG experiments.

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All Publications

2011: An Van den Bergh; Koen Wuyts; Luc Bijnens; Ron A H J Gilissen; Denise Morrison; Vikash Sinha; Roel Straetemans; Claire Mackie
Prediction of human oral plasma concentration-time profiles using preclinical data: comparative evaluation of prediction approaches in early pharmaceutical discovery.
Clinical pharmacokinetics 2011;50(8):505-17.
2010: Willem Talloen; Sepp Hochreiter; Luc Bijnens; Adetayo Kasim; Ziv Shkedy; Dhammika Amaratunga; Hinrich Göhlmann
Filtering data from high-throughput experiments based on measurement reliability.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):E173-4; author reply E175.
2010: Kristien Wouters; Jose Cortinas Abrahantes; Geert Molenberghs; Helena Geys; Abdellah Ahnaou; Wilhelmus H I M Drinkenburg; Luc Bijnens
Correction for model selection bias using a modified model averaging approach for supervised learning methods applied to EEG experiments.
Journal of biopharmaceutical statistics 2010;20(4):768-86.
2010: Tom Jacobs; Roel Straetemans; Geert Molenberghs; J Adriaan Bouwknecht; Luc Bijnens
A latent pharmacokinetic time profile to model dose-response survival data.
Journal of biopharmaceutical statistics 2010;20(4):759-67.
2010: Sepp Hochreiter; Ulrich Bodenhofer; Martin Heusel; Andreas Mayr; Andreas Mitterecker; Adetayo Kasim; Tatsiana Khamiakova; Suzy Van Sanden; Dan Lin; Willem Talloen; Luc Bijnens; Hinrich Göhlmann; Ziv Shkedy; Djork-Arné Clevert
FABIA: factor analysis for bicluster acquisition.
Bioinformatics (Oxford, England) 2010;26(12):1520-7.
2010: Adetayo Kasim; Dan Lin; Suzy Van Sanden; Djork-Arné Clevert; Luc Bijnens; Hinrich Göhlmann; Dhammika Amaratunga; Sepp Hochreiter; Ziv Shkedy; Willem Talloen
Informative or noninformative calls for gene expression: a latent variable approach.
Statistical applications in genetics and molecular biology 2010;9():Article 4.
2010: Roel Straetemans; Luc Bijnens
Application and review of the separate ray model to investigate interaction effects.
Frontiers in bioscience (Elite edition) 2010;2():266-78.
2009: Abel Tilahun; John T Maringwa; Helena Geys; Ariel Alonso; Leen Raeymaekers; Geert Molenberghs; Gerd Van Den Kieboom; Pim Drinkenburg; Luc Bijnens
Investigating association between behavior, corticosterone, heart rate, and blood pressure in rats using surrogate marker evaluation methodology.
Journal of biopharmaceutical statistics 2009;19(1):133-49.
2008: John T Maringwa; Helena Geys; Ziv Shkedy; Christel Faes; Geert Molenberghs; Marc Aerts; Karel Van Ammel; Ard Teisman; Luc Bijnens
Analysis of cross-over designs with serial correlation within periods using semi-parametric mixed models.
Statistics in medicine 2008;27(28):6009-33.
2008: Tom Jacobs; Filip De Ridder; Sarah Rusch; Achiel Van Peer; Geert Molenberghs; Luc Bijnens
Including information on the therapeutic window in bioequivalence acceptance.
Pharmaceutical research 2008;25(11):2628-38.
2008: D Lin; Z Shkedy; Tomasz Burzykowski; R Ion; Hinrich Göhlmann; A De Bondt; T Perer; T Geerts; I Van den Wyngaert; Luc Bijnens
An investigation on performance of Significance Analysis of Microarray (SAM) for the comparisons of several treatments with one control in the presence of small-variance genes.
Biometrical journal. Biometrische Zeitschrift 2008;50(5):801-23.
2008: Christel Faes; Marc Aerts; Geert Molenberghs; Helena Geys; Greet Teuns; Luc Bijnens
A high-dimensional joint model for longitudinal outcomes of different nature.
Statistics in medicine 2008;27(22):4408-27.
2008: Tom Jacobs; Stefaan Rossenu; Adrian Dunne; Geert Molenberghs; Roel Straetemans; Luc Bijnens
Combined models for data from in vitro-in vivo correlation experiments.
Journal of biopharmaceutical statistics 2008;18(6):1197-211.
2008: Kristien Wouters; Jose Cortinas Abrahantes; Geert Molenberghs; Abdellah Ahnaou; Wilhelmus H I M Drinkenburg; Luc Bijnens
A comparison of doubly hierarchical discriminant analyses for multiple class longitudinal data from EEG experiments.
Journal of biopharmaceutical statistics 2008;18(6):1120-35.
2008: John T Maringwa; Helena Geys; Ziv Shkedy; Christel Faes; Geert Molenberghs; Marc Aerts; Karel Van Ammel; Ard Teisman; Luc Bijnens
Application of semiparametric mixed models and simultaneous confidence bands in a cardiovascular safety experiment with longitudinal data.
Journal of biopharmaceutical statistics 2008;18(6):1043-62.
2007: Willem Talloen; Djork-Arné Clevert; Sepp Hochreiter; Dhammika Amaratunga; Luc Bijnens; Stefan U Kass; Hinrich Göhlmann
I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data.
Bioinformatics (Oxford, England) 2007;23(21):2897-902.
2007: Dan Lin; Ziv Shkedy; Dani Yekutieli; Tomasz Burzykowski; Hinrich Göhlmann; An De Bondt; Tim Perera; Tamara Geerts; Luc Bijnens
Testing for trends in dose-response microarray experiments: a comparison of several testing procedures, multiplicity and resampling-based inference.
Statistical applications in genetics and molecular biology 2007;6():Article26.
2007: J T Marringwa; Christel Faes; Marc Aerts; Helena Geys; G Teuns; B Van Den Poel; Luc Bijnens
On the use of historical control data in pre-clinical safety studies.
Journal of biopharmaceutical statistics 2007;17(3):493-509.
2006: Ann Beliën; Stefanie De Schepper; wim joanna floren; Boudewijn Janssens; Ann Mariën; Peter King; Jacky Van Dun; Luc Andries; Jan Voeten; Luc Bijnens; Michel Janicot; Janine Arts
Real-time gene expression analysis in human xenografts for evaluation of histone deacetylase inhibitors.
Molecular cancer therapeutics 2006;5(9):2317-23.
2006: Suzy Van Sanden; Luc Wouters; Tomasz Burzykowski; Geert Molenberghs; Marie Van Remoortere; Theo F Meert; Luc Bijnens
A modeling approach to the analysis of nerve regenerative experiments.
Journal of biopharmaceutical statistics 2006;16(6):843-59.
2006: Philippe Vandenbroeck; Luc Wouters; Geert Molenberghs; Jef Van Gestel; Luc Bijnens
Teaching statistical thinking to life scientists a case-based approach.
Journal of biopharmaceutical statistics 2006;16(1):61-75.
2005: Roel Straetemans; Timothy O'Brien; Luc Wouters; Jacky Van Dun; Michel Janicot; Luc Bijnens; Tomasz Burzykowski; Marc Aerts
Design and analysis of drug combination experiments.
Biometrical journal. Biometrische Zeitschrift 2005;47(3):299-308.
2005: Ziv Shkedy; Veerle Vandersmissen; Geert Molenberghs; Hansfried Van Craenendonck; Nancy Aerts; Thomas Steckler; Luc Bijnens
Behavioral testing of antidepressant compounds: an analysis of crossover design for correlated binary data.
Biometrical journal. Biometrische Zeitschrift 2005;47(3):286-98.
2005: Ziv Shkedy; Geert Molenberghs; Hansfried Van Craenendonck; Thomas Steckler; Luc Bijnens
A hierarchical Binomial-Poisson model for the analysis of a crossover design for correlated binary data when the number of trials is dose-dependent.
Journal of biopharmaceutical statistics 2005;15(2):225-39.
2005: Ziv Shkedy; Roel Straetemans; Geert Molenberghs; Miek Desmidt; Petra Vinken; Nick Goeminne; Werner Coussement; Bob Van Den Poel; Luc Bijnens
Modeling anti-KLH ELISA data using two-stage and mixed effects models in support of immunotoxicological studies.
Journal of biopharmaceutical statistics 2005;15(2):205-23.
2004: Wim J E P Lammers; Christel Faes; Betty Stephen; Luc Bijnens; Luc Ver Donck; Jan A J Schuurkes
Spatial determination of successive spikes in the isolated cat duodenum.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2004;16(6):775-83.
2004: Pieter J Peeters; Hinrich Göhlmann; Ilse Van den Wyngaert; Sigrid M Swagemakers; Luc Bijnens; Stefan U Kass; Thomas Steckler
Transcriptional response to corticotropin-releasing factor in AtT-20 cells.
Molecular pharmacology 2004;66(5):1083-92.
2003: Luc Wouters; Hinrich Göhlmann; Luc Bijnens; Stefan U Kass; Geert Molenberghs; Paul J Lewi
Graphical exploration of gene expression data: a comparative study of three multivariate methods.
Biometrics 2003;59(4):1131-9.
2003: Weichung Joe Shih; Peter Ouyang; Hui Quan; Yong Lin; Bart Michiels; Luc Bijnens
Controlling type I error rate for fast track drug development programmes.
Statistics in medicine 2003;22(5):665-75.
2002: Bart Michiels; Geert Molenberghs; Luc Bijnens; Tony Vangeneugden; Herbert Thijs
Selection models and pattern-mixture models to analyse longitudinal quality of life data subject to drop-out.
Statistics in medicine 2002;21(8):1023-41.
2001: L Duchateau; J P Pignon; Luc Bijnens; S Bertin; J Bourhis; R Sylvester
Individual patient-versus literature-based meta-analysis of survival data: time to event and event rate at a particular time can make a difference, an example based on head and neck cancer.
Controlled clinical trials 2001;22(5):538-47.
1999: Brigitte Maes; P Meeus; Lucienne Michaux; Luc Bijnens; Marc Boogaerts; Anne Hagemeijer; Christiane De Wolf-Peeters; Gregor Verhoef
Application of the International Prognostic Scoring System for myelodysplastic syndromes.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(7):825-9.
1998: Mike Clarke; L Stewart; J P Pignon; Luc Bijnens
Individual patient data meta-analysis in cancer.
British journal of cancer 1998;77(11):2036-44.
1997: PC Clahsen; Cornelis J H van de Velde; A Goldhirsch; J Rossbach; M R Sertoli; Luc Bijnens; Richard J Sylvester
Overview of randomized perioperative polychemotherapy trials in women with early-stage breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(7):2526-35.
1997: Jacobus H Meerwaldt; Patrice Carde; R Somers; José Thomas; Johanna C Kluin-Nelemans; Dominique Bron; Evert M Noordijk; J M Cosset; Luc Bijnens; Ivana Teodorovic; Anton Hagenbeek
Persistent improved results after adding vincristine and bleomycin to a cyclophosphamide/hydroxorubicin/Vm-26/prednisone combination (CHVmP) in stage III-IV intermediate- and high-grade non-Hodgkin's lymphoma. The EORTC Lymphoma Cooperative Group.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8 Suppl 1():67-70.
1996: A Pawinski; R Sylvester; K H Kurth; C Bouffioux; A van der Meijden; M K Parmar; Luc Bijnens
A combined analysis of European Organization for Research and Treatment of Cancer, and Medical Research Council randomized clinical trials for the prophylactic treatment of stage TaT1 bladder cancer. European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group and the Medical Research Council Working Party on Superficial Bladder Cancer.
The Journal of urology 1996;156(6):1934-40, discussion 1940-1.
1996: S Pittaluga; Luc Bijnens; Ivana Teodorovic; Anton Hagenbeek; J H Meerwaldt; R Somers; José Thomas; Evert M Noordijk; C De Wolf-Peeters
Clinical analysis of 670 cases in two trials of the European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group subtyped according to the Revised European-American Classification of Lymphoid Neoplasms: a comparison with the Working Formulation.
Blood 1996;87(10):4358-67.
1996: A Pawinski; R Sylvester; C Bouffioux; K H Kurth; M Parmar; Luc Bijnens
A combined analysis of EORTC/MRC randomized clinical trials for the prophylactic treatment of TaT1 bladder cancer. Eortc Genito-Urinary Tract Cancer Cooperative Group and the Medical Research Council Working Party on Superficial Bladder Cancer.
Acta urologica Belgica 1996;64(2):27.
1995: Ivana Teodorovic; S Pittaluga; Johanna C Kluin-Nelemans; J H Meerwaldt; Anton Hagenbeek; Martine Van Glabbeke; R Somers; Luc Bijnens; Evert M Noordijk; C D Peeters
Efficacy of four different regimens in 64 mantle-cell lymphoma cases: clinicopathologic comparison with 498 other non-Hodgkin's lymphoma subtypes. European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(11):2819-26.