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Tom Obrig

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Publications

TOP 3
Fumiko Obata; Koujiro Tohyama; Adrian D Bonev; GL Kolling; Tiffany R Keepers; Lisa K Gross; Mark T Nelson; Shigehiro Sato; Tom G Obrig
Shiga toxin 2 affects the central nervous system through receptor globotriaosylceramide localized to neurons.
GL Kolling; Fumiko Obata; Lisa K Gross; Tom G Obrig
Immunohistologic techniques for detecting the glycolipid Gb(3) in the mouse kidney and nervous system.
Matthew K Stone; GL Kolling; Matthew H Lindner; Tom G Obrig
p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cells.

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All Publications

2008: Fumiko Obata; Koujiro Tohyama; Adrian D Bonev; GL Kolling; Tiffany R Keepers; Lisa K Gross; Mark T Nelson; Shigehiro Sato; Tom G Obrig
Shiga toxin 2 affects the central nervous system through receptor globotriaosylceramide localized to neurons.
The Journal of infectious diseases 2008;198(9):1398-406.
2008: GL Kolling; Fumiko Obata; Lisa K Gross; Tom G Obrig
Immunohistologic techniques for detecting the glycolipid Gb(3) in the mouse kidney and nervous system.
Histochemistry and cell biology 2008;130(1):157-64.
2008: Matthew K Stone; GL Kolling; Matthew H Lindner; Tom G Obrig
p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cells.
Infection and immunity 2008;76(3):1115-21.
2008: Christopher C Moore; Edward N Martin; Grace H Lee; Tom G Obrig; Joel Linden; W Michael Scheld
An A2A adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models.
BMC infectious diseases 2008;8():141.
2007: Tiffany R Keepers; Lisa K Gross; Tom G Obrig
Monocyte chemoattractant protein 1, macrophage inflammatory protein 1 alpha, and RANTES recruit macrophages to the kidney in a mouse model of hemolytic-uremic syndrome.
Infection and immunity 2007;75(3):1229-36.
2007: James K Roche; Tiffany R Keepers; Lisa K Gross; Regina M Seaner; Tom G Obrig
CXCL1/KC and CXCL2/MIP-2 are critical effectors and potential targets for therapy of Escherichia coli O157:H7-associated renal inflammation.
The American journal of pathology 2007;170(2):526-37.
2006: Tiffany R Keepers; Mitchell A Psotka; Lisa K Gross; Tom G Obrig
A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease.
Journal of the American Society of Nephrology : JASN 2006;17(12):3404-14.
2006: Manuela J M de Klaver; Gregory S Weingart; Tom G Obrig; George F Rich
Local anesthetic-induced protection against lipopolysaccharide-induced injury in endothelial cells: the role of mitochondrial adenosine triphosphate-sensitive potassium channels.
Anesthesia and analgesia 2006;102(4):1108-13.
2006: Benedito A Carneiro; Jun Fujii; G A C Brito; Cirle Alcantara; Reinaldo Oria; Aldo A M Lima; Tom G Obrig; Richard L Guerrant
Caspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxin A effects by glutamine and alanyl-glutamine in vivo and in vitro.
Infection and immunity 2006;74(1):81-7.
2005: Fadila Guessous; Marek Marcinkiewicz; Renata Polanowska-Grabowska; Sudawadee Kongkhum; Daniel Heatherly; Tom G Obrig; Adrian R L Gear
Shiga toxin 2 and lipopolysaccharide induce human microvascular endothelial cells to release chemokines and factors that stimulate platelet function.
Infection and immunity 2005;73(12):8306-16.
2005: Fadila Guessous; Marek Marcinkiewicz; Renata Polanowska-Grabowska; Tiffany R Keepers; Tom G Obrig; Adrian R L Gear
Shiga toxin 2 and lipopolysaccharide cause monocytic THP-1 cells to release factors which activate platelet function.
Thrombosis and haemostasis 2005;94(5):1019-27.
2004: Benedito A Carneiro-Filho; Reinaldo Oria; Katie Wood Rea; G A C Brito; Jun Fujii; Tom G Obrig; Aldo A M Lima; Richard L Guerrant
Alanyl-glutamine hastens morphologic recovery from 5-fluorouracil-induced mucositis in mice.
Nutrition (Burbank, Los Angeles County, Calif.) 2004;20(10):934-41.
2004: S A Ghosh; Renata Polanowska-Grabowska; Jun Fujii; Tom G Obrig; Adrian R L Gear
Shiga toxin binds to activated platelets.
Journal of thrombosis and haemostasis : JTH 2004;2(3):499-506.
2003: Jun Fujii; Takashi Matsui; Daniel P Heatherly; Kailo H Schlegel; Peter I Lobo; Takashi Yutsudo; Georgianne M Ciraolo; Randal E Morris; Tom G Obrig
Rapid apoptosis induced by Shiga toxin in HeLa cells.
Infection and immunity 2003;71(5):2724-35.
2003: Tom G Obrig; Regina M Seaner; M Bentz; Clifford A Lingwood; B Boyd; A Smith; W Narrow
Induction by sphingomyelinase of shiga toxin receptor and shiga toxin 2 sensitivity in human microvascular endothelial cells.
Infection and immunity 2003;71(2):845-9.
2002: G A C Brito; Jun Fujji; Benedito A Carneiro-Filho; Aldo A M Lima; Tom G Obrig; Richard L Guerrant
Mechanism of Clostridium difficile toxin A-induced apoptosis in T84 cells.
The Journal of infectious diseases 2002;186(10):1438-47.
2002: Eric Houpt; David J Glembocki; Tom G Obrig; Christopher A Moskaluk; Lauren A Lockhart; Rhonda L Wright; Regina M Seaner; Tiffany R Keepers; Tracy D Wilkins; William A Petri
The mouse model of amebic colitis reveals mouse strain susceptibility to infection and exacerbation of disease by CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4496-503.
2001: Jun Fujii; Y Kinoshita; Takashi Yutsudo; Hatsumi Taniguchi; Tom G Obrig; Shin-ichi Yoshida
Toxicity of Shiga toxin 1 in the central nervous system of rabbits.
Infection and immunity 2001;69(10):6545-8.
2000: Delia Viisoreanu; Renata Polanowska-Grabowska; Sudawadee Kongkhum; Tom G Obrig; Adrian R L Gear
Human platelet aggregation is not altered by Shiga toxins 1 or 2.
Thrombosis research 2000;98(5):403-10.