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James Calvet

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Kyle Jansson; Brenda S Magenheimer; Anh-Nguyet T Nguyen; Gail Reif; Darren P Wallace; Lavakumar Reddy Aramadhaka; Elsa Bello-Reuss; James P Calvet; Gustavo Blanco
Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways.
Stephen C Parnell; Sanjeev Puri; Darren P Wallace; James P Calvet
Protein phosphatase-1α interacts with and dephosphorylates polycystin-1.
Daisuke Yoshihara; Takafumi Toyohara; Darren P Wallace; Tamio Yamaguchi; Takaaki Abe; Harold M Aukema; James P Calvet; Yoshiyuki Hiki; Masanori Kugita; Hiroki Kurahashi; Miwa Morita; Shizuko Nagao
Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease.

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2012: Kyle Jansson; Brenda S Magenheimer; Anh-Nguyet T Nguyen; Gail Reif; Darren P Wallace; Lavakumar Reddy Aramadhaka; Elsa Bello-Reuss; James P Calvet; Gustavo Blanco
Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways.
American journal of physiology. Renal physiology 2012;303(7):F982-90.
2012: Stephen C Parnell; Sanjeev Puri; Darren P Wallace; James P Calvet
Protein phosphatase-1α interacts with and dephosphorylates polycystin-1.
PloS one 2012;7(6):e36798.
2012: Daisuke Yoshihara; Takafumi Toyohara; Darren P Wallace; Tamio Yamaguchi; Takaaki Abe; Harold M Aukema; James P Calvet; Yoshiyuki Hiki; Masanori Kugita; Hiroki Kurahashi; Miwa Morita; Shizuko Nagao
Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease.
PPAR research 2012;2012():695898.
2011: Daisuke Yoshihara; Hiroki Kurahashi; Miwa Morita; Masanori Kugita; Yoshiyuki Hiki; Harold M Aukema; Tamio Yamaguchi; James P Calvet; Darren P Wallace; Shizuko Nagao
PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease.
American journal of physiology. Renal physiology 2011;300(2):F465-74.
2011: Masanori Kugita; Kazuhiro Nishii; Miwa Morita; Daisuke Yoshihara; Hiroe Kowa-Sugiyama; Kouji Yamada; Tamio Yamaguchi; Darren P Wallace; James P Calvet; Hiroki Kurahashi; Shizuko Nagao
Global gene expression profiling in early-stage polycystic kidney disease in the Han:SPRD Cy rat identifies a role for RXR signaling.
American journal of physiology. Renal physiology 2011;300(1):F177-88.
2010: M Rafiq Islam; Tamara Jimenez; Christopher Pelham; Marianna Rodova; Sanjeev Puri; Brenda S Magenheimer; Robin L Maser; Christian Widmann; James P Calvet
MAP/ERK kinase kinase 1 (MEKK1) mediates transcriptional repression by interacting with polycystic kidney disease-1 (PKD1) promoter-bound p53 tumor suppressor protein.
The Journal of biological chemistry 2010;285(50):38818-31.
2010: Tamio Yamaguchi; Gail Reif; James P Calvet; Darren P Wallace
Sorafenib inhibits cAMP-dependent ERK activation, cell proliferation, and in vitro cyst growth of human ADPKD cyst epithelial cells.
American journal of physiology. Renal physiology 2010;299(5):F944-51.
2010: Shizuko Nagao; Miwa Morita; Masanori Kugita; Daisuke Yoshihara; Tamio Yamaguchi; Hiroki Kurahashi; James P Calvet; Darren P Wallace
Polycystic kidney disease in Han:SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.
American journal of physiology. Renal physiology 2010;299(5):F1078-86.
2009: Hiroo Katayama; Mitchell McGill; Andrew Kearns; Marek Brzozowski; Nicholas Degner; Bliss Harnett; Boris Kornilayev; Dubravka Matković-Calogović; Todd Holyoak; James P Calvet; Edward P Gogol; John Seed; Mark T Fisher
Strategies for folding of affinity tagged proteins using GroEL and osmolytes.
Journal of structural and functional genomics 2009;10(1):57-66.
2008: M Rafiq Islam; Sanjeev Puri; Marianna Rodova; Brenda S Magenheimer; Robin L Maser; James P Calvet
Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter.
American journal of physiology. Renal physiology 2008;295(6):F1845-54.
2008: James P Calvet
Strategies to inhibit cyst formation in ADPKD.
Clinical journal of the American Society of Nephrology : CJASN 2008;3(4):1205-11.
2008: Shizuko Nagao; K Nishii; D Yoshihara; H Kurahashi; K Nagaoka; T Yamashita; H Takahashi; T Yamaguchi; James P Calvet; Darren P Wallace
Calcium channel inhibition accelerates polycystic kidney disease progression in the Cy/+ rat.
Kidney international 2008;73(3):269-77.
2006: Brenda S Magenheimer; Patricia L St John; Kathryn Isom; Dale R Abrahamson; Robert C De Lisle; Darren P Wallace; Robin L Maser; Jared J Grantham; James P Calvet
Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation.
Journal of the American Society of Nephrology : JASN 2006;17(12):3424-37.
2006: Diederik Van Bodegom; Zubaida Saifudeen; Susana Dipp; Sanjeev Puri; Brenda S Magenheimer; James P Calvet; Samir S El-Dahr
The polycystic kidney disease-1 gene is a target for p53-mediated transcriptional repression.
The Journal of biological chemistry 2006;281(42):31234-44.
2006: Zhousheng Xiao; Shiqin Zhang; Josh Mahlios; Gan Zhou; Brenda S Magenheimer; Dayong Guo; Sarah L Dallas; Robin L Maser; James P Calvet; Lynda F Bonewald; L Darryl Quarles
Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression.
The Journal of biological chemistry 2006;281(41):30884-95.
2006: Sanjeev Puri; Marianna Rodova; M Rafiq Islam; Brenda S Magenheimer; Robin L Maser; James P Calvet
Ets factors regulate the polycystic kidney disease-1 promoter.
Biochemical and biophysical research communications 2006;342(4):1005-13.
2004: Sanjeev Puri; Brenda S Magenheimer; Robin L Maser; Erin M Ryan; Christopher A Zien; Danielle D Walker; Darren P Wallace; Scott J Hempson; James P Calvet
Polycystin-1 activates the calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway.
The Journal of biological chemistry 2004;279(53):55455-64.
2004: Tamio Yamaguchi; Darren P Wallace; Brenda S Magenheimer; Scott J Hempson; Jared J Grantham; James P Calvet
Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype.
The Journal of biological chemistry 2004;279(39):40419-30.
2003: Marianna Rodova; M Rafiq Islam; Kenneth R Peterson; James P Calvet
Remarkable sequence conservation of the last intron in the PKD1 gene.
Molecular biology and evolution 2003;20(10):1669-74.
2003: James P Calvet
New insights into ciliary function: kidney cysts and photoreceptors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5583-5.
2003: Robin L Maser; Brenda S Magenheimer; Christopher A Zien; James P Calvet
Transient transfection assays for analysis of signal transduction in renal cells.
Methods in molecular medicine 2003;86():205-17.
2002: Marianna Rodova; M Rafiq Islam; Robin L Maser; James P Calvet
The polycystic kidney disease-1 promoter is a target of the beta-catenin/T-cell factor pathway.
The Journal of biological chemistry 2002;277(33):29577-83.
2002: Daniel Wolf; Marianna Rodova; Eric A Miska; James P Calvet; Tony Kouzarides
Acetylation of beta-catenin by CREB-binding protein (CBP).
The Journal of biological chemistry 2002;277(28):25562-7.
2002: Stephen C Parnell; Brenda S Magenheimer; Robin L Maser; Christopher A Zien; Anna-Maria Frischauf; James P Calvet
Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.
The Journal of biological chemistry 2002;277(22):19566-72.
2002: Aric W Ledford; Jennifer Brantley; Gabor Kemeny; Tonia L Foreman; Susan E Quaggin; Peter Igarashi; Stephanie M Oberhaus; Marianna Rodova; James P Calvet; Gregory B Vanden Heuvel
Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia.
Developmental biology 2002;245(1):157-71.
2002: Robin L Maser; Dianne Vassmer; Brenda S Magenheimer; James P Calvet
Oxidant stress and reduced antioxidant enzyme protection in polycystic kidney disease.
Journal of the American Society of Nephrology : JASN 2002;13(4):991-9.
2001: Michael Sutters; Tamio Yamaguchi; Robin L Maser; Brenda S Magenheimer; Patricia L St John; Dale R Abrahamson; Jared J Grantham; James P Calvet
Polycystin-1 transforms the cAMP growth-responsive phenotype of M-1 cells.
Kidney international 2001;60(2):484-94.
2001: James P Calvet; Jared J Grantham
The genetics and physiology of polycystic kidney disease.
Seminars in nephrology 2001;21(2):107-23.
2001: Jared J Grantham; James P Calvet
Polycystic kidney disease: In danger of being X-rated?
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):790-2.
2000: J L Ricker; Vincent H Gattone; James P Calvet; CA Rankin
Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice.
Journal of the American Society of Nephrology : JASN 2000;11(10):1837-47.
1999: Stephen C Parnell; Brenda S Magenheimer; Robin L Maser; James P Calvet
Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain.
Biochemical and biophysical research communications 1999;259(3):539-43.
1999: CA Rankin; Yoshifumi Itoh; C Tian; D M Ziemer; James P Calvet; Vincent H Gattone
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.
Journal of the American Society of Nephrology : JASN 1999;10(2):210-7.
1998: Stephen C Parnell; Brenda S Magenheimer; Robin L Maser; CA Rankin; A Smine; Tetsuji Okamoto; James P Calvet
The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro.
Biochemical and biophysical research communications 1998;251(2):625-31.
1998: James P Calvet
Molecular genetics of polycystic kidney disease.
Journal of nephrology 1998;11(1):24-34.
1996: C A Rankin; Kazushi Suzuki; Yoshifumi Itoh; D M Ziemer; Jared J Grantham; James P Calvet; Hideaki Nagase
Matrix metalloproteinases and TIMPS in cultured C57BL/6J-cpk kidney tubules.
Kidney international 1996;50(3):835-44.
1996: C J Davidow; Robin L Maser; L A Rome; James P Calvet; Jared J Grantham
The cystic fibrosis transmembrane conductance regulator mediates transepithelial fluid secretion by human autosomal dominant polycystic kidney disease epithelium in vitro.
Kidney international 1996;50(1):208-18.
1996: X Hou; Robin L Maser; Brenda S Magenheimer; James P Calvet
A mouse kidney- and liver-expressed cDNA having homology with a prokaryotic parathion hydrolase (phosphotriesterase)-encoding gene: abnormal expression in injured and polycystic kidneys.
Gene 1996;168(2):157-63.
1996: C A Rankin; D M Ziemer; Robin L Maser; I Foo; James P Calvet
Growth characteristics of cells cultured from two murine models of polycystic kidney disease.
In vitro cellular & developmental biology. Animal 1996;32(2):100-6.
1996: Vincent H Gattone; K A Kuenstler; G W Lindemann; X Lu; Benjamin D Cowley; C A Rankin; James P Calvet
Renal expression of a transforming growth factor-alpha transgene accelerates the progression of inherited, slowly progressive polycystic kidney disease in the mouse.
The Journal of laboratory and clinical medicine 1996;127(2):214-22.
1995: Robin L Maser; James P Calvet
Analysis of differential gene expression in the kidney by differential cDNA screening, subtractive cloning, and mRNA differential display.
Seminars in nephrology 1995;15(1):29-42.
1994: James P Calvet; L J Chadwick
Primary and secondary genetic responses after folic acid-induced acute renal injury in the mouse.
Journal of the American Society of Nephrology : JASN 1994;5(6):1324-32.
1994: Robin L Maser; Brenda S Magenheimer; James P Calvet
Mouse plasma glutathione peroxidase. cDNA sequence analysis and renal proximal tubular expression and secretion.
The Journal of biological chemistry 1994;269(43):27066-73.
1994: D A Lowden; G W Lindemann; G Merlino; B D Barash; James P Calvet; Vincent H Gattone
Renal cysts in transgenic mice expressing transforming growth factor-alpha.
The Journal of laboratory and clinical medicine 1994;124(3):386-94.
1994: James P Calvet
Injury and development in polycystic kidney disease.
Current opinion in nephrology and hypertension 1994;3(3):340-8.
1993: Benjamin D Cowley; S Gudapaty; A L Kraybill; B D Barash; M A Harding; James P Calvet; Vincent H Gattone
Autosomal-dominant polycystic kidney disease in the rat.
Kidney international 1993;43(3):522-34.
1993: James P Calvet
Polycystic kidney disease: primary extracellular matrix abnormality or defective cellular differentiation?
Kidney international 1993;43(1):101-8.
1993: EH Birkenmeier; Verity A Letts; Wayne N Frankel; Brenda S Magenheimer; James P Calvet
Sulfated glycoprotein-2 (Sgp-2) maps to mouse chromosome 14.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(2):131-2.
1992: C A Rankin; Jared J Grantham; James P Calvet
C-fos expression is hypersensitive to serum-stimulation in cultured cystic kidney cells from the C57BL/6J-cpk mouse.
Journal of cellular physiology 1992;152(3):578-86.
1992: M A Harding; Vincent H Gattone; Jared J Grantham; James P Calvet
Localization of overexpressed c-myc mRNA in polycystic kidneys of the cpk mouse.
Kidney international 1992;41(2):317-25.
1991: M A Harding; L J Chadwick; Vincent H Gattone; James P Calvet
The SGP-2 gene is developmentally regulated in the mouse kidney and abnormally expressed in collecting duct cysts in polycystic kidney disease.
Developmental biology 1991;146(2):483-90.
1991: Vincent H Gattone; James P Calvet
Murine infantile polycystic kidney disease: a role for reduced renal epidermal growth factor.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1991;17(6):606-7.
1991: Benjamin D Cowley; L J Chadwick; Jared J Grantham; James P Calvet
Elevated proto-oncogene expression in polycystic kidneys of the C57BL/6J (cpk) mouse.
Journal of the American Society of Nephrology : JASN 1991;1(8):1048-53.
1990: Vincent H Gattone; Glen K Andrews; F W Niu; L J Chadwick; R M Klein; James P Calvet
Defective epidermal growth factor gene expression in mice with polycystic kidney disease.
Developmental biology 1990;138(1):225-30.
1989: R Mangoo-Karim; M E Uchic; M Grant; W A Shumate; James P Calvet; C H Park; Jared J Grantham
Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(14):2629-32.
1989: Robin L Maser; James P Calvet
U3 small nuclear RNA can be psoralen-cross-linked in vivo to the 5' external transcribed spacer of pre-ribosomal-RNA.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6523-7.
1989: Benjamin D Cowley; L J Chadwick; Jared J Grantham; James P Calvet
Sequential protooncogene expression in regenerating kidney following acute renal injury.
The Journal of biological chemistry 1989;264(14):8389-93.
1989: Jared J Grantham; R Mangoo-Karim; M E Uchic; M Grant; W A Shumate; C H Park; James P Calvet
Net fluid secretion by mammalian renal epithelial cells: stimulation by cAMP in polarized cultures derived from established renal cells and from normal and polycystic kidneys.
Transactions of the Association of American Physicians 1989;102():158-62.
1988: Vincent H Gattone; James P Calvet; Benjamin D Cowley; A P Evan; T S Shaver; K Helmstadter; Jared J Grantham
Autosomal recessive polycystic kidney disease in a murine model. A gross and microscopic description.
Laboratory investigation; a journal of technical methods and pathology 1988;59(2):231-8.
1987: Benjamin D Cowley; F L Smardo; Jared J Grantham; James P Calvet
Elevated c-myc protooncogene expression in autosomal recessive polycystic kidney disease.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8394-8.
1987: James P Calvet; J A Myers
In-vivo secondary structure analysis of the small nuclear RNA U1 using psoralen cross-linking.
Journal of molecular biology 1987;197(3):543-53.
1987: Glen K Andrews; M A Harding; James P Calvet; E D Adamson
The heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene.
Molecular and cellular biology 1987;7(10):3452-8.
1987: F L Smardo; James P Calvet
Sequence analysis of the glutamate tRNA family: evidence for pseudogenes.
Gene 1987;57(2-3):213-20.
1986: G R Kunkel; Robin L Maser; James P Calvet; T Pederson
U6 small nuclear RNA is transcribed by RNA polymerase III.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(22):8575-9.