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Uday Kompella

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Ling Luo; Christina Mamalis; Tadashi R Miya; Thomas Olsen; Yureeda Qazi; Nirbhai Singh; Sangly P Srinivas; Brian C Stagg; Puneet Tyagi; Hironori Uehara; Ross Whitaker; Xiaohui Zhang; Kristen Zygmunt; Jayakrishna Ambati; Bonnie Archer; Judit Baffi; Péter Barabás; Srinivas R Chennamaneni; Subrata K Das; Lyska Emerson; Guangping Gao; Yoshio Hirano; Wei Huang; Kyle Jackman; Uday B Kompella; David Krizaj; Faisal Ahmed; Balamurali K Ambati
Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.
Uday B Kompella
Nanotechnology and drug delivery.
Sarath Yandrapu; Uday B Kompella
Development of sustained-release microspheres for the delivery of SAR 1118, an LFA-1 antagonist intended for the treatment of vascular complications of the eye.

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2013: Ling Luo; Christina Mamalis; Tadashi R Miya; Thomas Olsen; Yureeda Qazi; Nirbhai Singh; Sangly P Srinivas; Brian C Stagg; Puneet Tyagi; Hironori Uehara; Ross Whitaker; Xiaohui Zhang; Kristen Zygmunt; Jayakrishna Ambati; Bonnie Archer; Judit Baffi; Péter Barabás; Srinivas R Chennamaneni; Subrata K Das; Lyska Emerson; Guangping Gao; Yoshio Hirano; Wei Huang; Kyle Jackman; Uday B Kompella; David Krizaj; Faisal Ahmed; Balamurali K Ambati
Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.
ACS nano 2013;7(4):3264-75.
2013: Uday B Kompella
Nanotechnology and drug delivery.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2013;29(2):89.
2013: Sarath Yandrapu; Uday B Kompella
Development of sustained-release microspheres for the delivery of SAR 1118, an LFA-1 antagonist intended for the treatment of vascular complications of the eye.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2013;29(2):236-48.
2013: Rajendra Shriram Kadam; Sunil K Vooturi; Uday B Kompella
Immunohistochemical and functional characterization of peptide, organic cation, neutral and basic amino acid, and monocarboxylate drug transporters in human ocular tissues.
Drug metabolism and disposition: the biological fate of chemicals 2013;41(2):466-74.
2013: Paola Bargagna-Mohan; Sunil P Deokule; Uday B Kompella; Cidambi Srinivasan; Kyle Thompson; Sunil Vooturi; John Wizeman; Royce Mohan
Withaferin a effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis.
PloS one 2013;8(5):e63881.
2013: Christina L Aquilante; David W A Bourne; Lane Bushman; Elizabeth B Daily; Kyle P Hammond; Charles W Hopley; Rajendra Shriram Kadam; Alexander T Kanack; Uday B Kompella; Lisa A Kosmiski; Merry Le; Julie A Predhomme; Joseph E Rower; Maha S Sidhom
Impact of the CYP2C8 *3 polymorphism on the drug-drug interaction between gemfibrozil and pioglitazone.
British journal of clinical pharmacology 2013;75(1):217-26.
2012: Ruchit Trivedi; Elizabeth F Redente; David W H Riches; Ashish Thakur; Uday B Kompella
Local delivery of biodegradable pirfenidone nanoparticles ameliorates bleomycin-induced pulmonary fibrosis in mice.
Nanotechnology 2012;23(50):505101.
2012: Rajendra Shriram Kadam; Robert I Scheinman; Uday B Kompella
Pigmented-MDCK (P-MDCK) cell line with tunable melanin expression: an in vitro model for the outer blood-retinal barrier.
Molecular pharmaceutics 2012;9(11):3228-35.
2012: Sunil K Vooturi; Rajendra Shriram Kadam; Uday B Kompella
Transporter targeted gatifloxacin prodrugs: synthesis, permeability, and topical ocular delivery.
Molecular pharmaceutics 2012;9(11):3136-46.
2012: Neera Tewari-Singh; Puneet Tyagi; Chapla Agarwal; David A Ammar; Robert W Enzenauer; Swetha Inturi; Anil K Jain; Uday B Kompella; J Mark Petrash; Rajesh Agarwal
Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries.
Toxicology and applied pharmacology 2012;264(1):23-31.
2012: Hu Yang; Puneet Tyagi; Christopher A Holden; Rajendra S Kadam; Uday B Kompella
Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration.
ACS nano 2012;6(9):7595-606.
2012: Rajendra Shriram Kadam; Henry F Edelhauser; Puneet Tyagi; Uday B Kompella
Influence of choroidal neovascularization and biodegradable polymeric particle size on transscleral sustained delivery of triamcinolone acetonide.
International journal of pharmaceutics 2012;434(1-2):140-7.
2012: Rajendra Shriram Kadam; David W A Bourne; Uday B Kompella
Nano-advantage in enhanced drug delivery with biodegradable nanoparticles: contribution of reduced clearance.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(7):1380-8.
2012: Christopher A Holden; Gajanan Jadhav; Rajendra Kadam; Uday B Kompella; Ashish Thakur; Puneet Tyagi; Hu Yang
Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(5):776-83.
2012: Yureeda Qazi; Jacquelyn Simonis; Nirbhai Singh; Swita Singh; Brian Stagg; Xiaohui Zhang; Uday B Kompella; Ling Luo; Balamurali K Ambati
Nanoparticle-mediated delivery of shRNA.VEGF-a plasmids regresses corneal neovascularization.
Investigative ophthalmology & visual science 2012;53(6):2837-44.
2012: Chandrasekar Durairaj; James E Chastain; Uday B Kompella
Intraocular distribution of melanin in human, monkey, rabbit, minipig and dog eyes.
Experimental eye research 2012;98():23-7.
2012: Yang Kyung Cho; Uday B Kompella; Ling Luo; Nirbhai Singh; Puneet Tyagi; Hironori Uehara; Jason R Young; Xiaohui Zhang; Bonnie Archer; Balamurali K Ambati
Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone.
Investigative ophthalmology & visual science 2012;53(4):2328-36.
2012: Pradip Malik; Narayan P S Cheruvu; Rajendra Shriram Kadam; Uday B Kompella
Hydrophilic prodrug approach for reduced pigment binding and enhanced transscleral retinal delivery of celecoxib.
Molecular pharmaceutics 2012;9(3):605-14.
2012: Shelley A Durazo; Uday B Kompella
Functionalized nanosystems for targeted mitochondrial delivery.
Mitochondrion 2012;12(2):190-201.
2012: Gabriel C Baltazar; Kathleen Boesze-Battaglia; Sonia Guha; Uday B Kompella; Alan M Laties; Jason Lim; Wennan Lu; Puneet Tyagi; Claire H Mitchell
Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells.
PloS one 2012;7(12):e49635.
2012: Puneet Tyagi; Rajendra Shriram Kadam; Uday B Kompella
Comparison of suprachoroidal drug delivery with subconjunctival and intravitreal routes using noninvasive fluorophotometry.
PloS one 2012;7(10):e48188.
2011: Robert I Scheinman; Ruchit Trivedi; Sam Vermillion; Uday B Kompella
Functionalized STAT1 siRNA nanoparticles regress rheumatoid arthritis in a mouse model.
Nanomedicine (London, England) 2011;6(10):1669-82.
2011: Ashish Thakur; Vidhya R Rao; Robert I Scheinman; Uday B Kompella
Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage.
Microvascular research 2011;82(3):346-50.
2011: Shelley A Durazo; Rajendra Shriram Kadam; Derek Drechsel; Manisha Patel; Uday B Kompella
Brain mitochondrial drug delivery: influence of drug physicochemical properties.
Pharmaceutical research 2011;28(11):2833-47.
2011: Rajendra Shriram Kadam; Gajanan Jadhav; Miller Ogidigben; Uday B Kompella
Ocular pharmacokinetics of dorzolamide and brinzolamide after single and multiple topical dosing: implications for effects on ocular blood flow.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(9):1529-37.
2011: Ji Jin; Uday B Kompella; Yang Hu; Kyoungmin Park; Puneet Tyagi; Xun Xu; Zhi Zheng; Kevin K Zhou; Jian-xing Ma
Anti-inflammatory and antiangiogenic effects of nanoparticle-mediated delivery of a natural angiogenic inhibitor.
Investigative ophthalmology & visual science 2011;52(9):6230-7.
2011: Ashish Thakur; Rajendra Kadam; Uday B Kompella
Trabecular meshwork and lens partitioning of corticosteroids: implications for elevated intraocular pressure and cataracts.
Archives of ophthalmology 2011;129(7):914-20.
2011: Rajendra Shriram Kadam; Narayan P S Cheruvu; Henry F Edelhauser; Uday B Kompella
Sclera-choroid-RPE transport of eight β-blockers in human, bovine, porcine, rabbit, and rat models.
Investigative ophthalmology & visual science 2011;52(8):5387-99.
2011: Carolyn K Pan; Hugo Quiroz-Mercado; Ogechi Agwu; Chandrasekar Durairaj; Uday B Kompella; Naresh Mandava; Scott C N Oliver; Jeffrey L Olson
Comparison of long-acting bevacizumab formulations in the treatment of choroidal neovascularization in a rat model.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2011;27(3):219-24.
2011: Ashish Thakur; Rajendra Shriram Kadam; Uday B Kompella
Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(5):771-81.
2011: Thomas Pfeifer; Marlene Buchebner; Prakash G Chandak; Jay V Patankar; Adelheid Kratzer; Sascha Obrowsky; Gerald N Rechberger; Rajendra Shriram Kadam; Uday B Kompella; Gerhard M Kostner; Dagmar Kratky; Sanja Levak-Frank
Synthetic LXR agonist suppresses endogenous cholesterol biosynthesis and efficiently lowers plasma cholesterol.
Current pharmaceutical biotechnology 2011;12(2):285-92.
2011: Rinku Baid; Robert I Scheinman; Toshimichi Shinohara; Dhirendra P Singh; Uday B Kompella
LEDGF(1-326) decreases P23H and wild type rhodopsin aggregates and P23H rhodopsin mediated cell damage in human retinal pigment epithelial cells.
PloS one 2011;6(9):e24616.
2011: Vidyullatha Vasireddy; Venkata R M Chavali; Jeffrey A Jamison; Victory T Joseph; Rajendra Kadam; Uday B Kompella; Jonathan H Lin; G Bhanuprakash Reddy; Radha Ayyagari
Rescue of photoreceptor degeneration by curcumin in transgenic rats with P23H rhodopsin mutation.
PloS one 2011;6(6):e21193.
2010: Henry F Edelhauser; Cheryl L Rowe-Rendleman; Michael R Robinson; Daniel G Dawson; Gerald J Chader; Hans E Grossniklaus; Kay D Rittenhouse; Clive G Wilson; David A Weber; Baruch D Kuppermann; Karl G Csaky; TW Olsen; Uday B Kompella; V Michael Holers; Gregory S Hageman; Brian C Gilger; Peter A Campochiaro; Scott M Whitcup; Wai Wong
Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications.
Investigative ophthalmology & visual science 2010;51(11):5403-20.
2010: Chandrasekar Durairaj; Rajendra Shriram Kadam; John W Chandler; Stephen L Hutcherson; Uday B Kompella
Nanosized dendritic polyguanidilyated translocators for enhanced solubility, permeability, and delivery of gatifloxacin.
Investigative ophthalmology & visual science 2010;51(11):5804-16.
2010: Vidhya R Rao; Elizabeth Prescott; Namdev B Shelke; Ruchit Trivedi; Peter Thomas; Craig Struble; tom gadek; Charles A O'Neill; Uday B Kompella
Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR).
Investigative ophthalmology & visual science 2010;51(10):5198-204.
2010: Uday B Kompella; Rajendra Shriram Kadam; Vincent H L Lee
Recent advances in ophthalmic drug delivery.
Therapeutic delivery 2010;1(3):435-56.
2010: Aniruddha Amrite; Vidya Pugazhenthi; Narayan Cheruvu; Uday B Kompella
Delivery of celecoxib for treating diseases of the eye: influence of pigment and diabetes.
Expert opinion on drug delivery 2010;7(5):631-45.
2010: Paul Missel; James Chastain; Ashim Mitra; Uday B Kompella; Viral Kansara; Sridhar Duvvuri; Aniruddha Amrite; Narayan Cheruvu
In vitro transport and partitioning of AL-4940, active metabolite of angiostatic agent anecortave acetate, in ocular tissues of the posterior segment.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2010;26(2):137-46.
2010: Ruchit Trivedi; Uday B Kompella
Nanomicellar formulations for sustained drug delivery: strategies and underlying principles.
Nanomedicine (London, England) 2010;5(3):485-505.
2010: Aaron S Mayo; Balamurali K Ambati; Uday B Kompella
Gene delivery nanoparticles fabricated by supercritical fluid extraction of emulsions.
International journal of pharmaceutics 2010;387(1-2):278-85.
2010: Rajendra Shriram Kadam; Uday B Kompella
Influence of lipophilicity on drug partitioning into sclera, choroid-retinal pigment epithelium, retina, trabecular meshwork, and optic nerve.
The Journal of pharmacology and experimental therapeutics 2010;332(3):1107-20.
2010: Gangadhar Sunkara; Surya P Ayalasomayajula; Jack DeRuiter; Uday B Kompella
Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor.
Brain research bulletin 2010;81(2-3):327-32.
2009: Sneha Sundaram; Ruchit Trivedi; Chandrasekar Durairaj; Rajagopal Ramesh; Balamurali K Ambati; Uday B Kompella
Targeted drug and gene delivery systems for lung cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(23):7299-308.
2009: Sneha Sundaram; Shyamal K Roy; Balamurali K Ambati; Uday B Kompella
Surface-functionalized nanoparticles for targeted gene delivery across nasal respiratory epithelium.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(11):3752-65.
2009: DE Barañano; S J Kim; Henry F Edelhauser; C Durairaj; Uday B Kompella; James T Handa
Efficacy and pharmacokinetics of intravitreal non-steroidal anti-inflammatory drugs for intraocular inflammation.
The British journal of ophthalmology 2009;93(10):1387-90.
2009: Chandrasekar Durairaj; Stephen J Kim; Henry F Edelhauser; Jaymin C Shah; Uday B Kompella
Influence of dosage form on the intravitreal pharmacokinetics of diclofenac.
Investigative ophthalmology & visual science 2009;50(10):4887-97.
2009: Shin J Kang; Chandrasekar Durairaj; Uday B Kompella; Joan M O'Brien; Hans E Grossniklaus
Subconjunctival nanoparticle carboplatin in the treatment of murine retinoblastoma.
Archives of ophthalmology 2009;127(8):1043-7.
2009: Kyoungmin Park; Ying Chen; Yang Hu; Aaron S Mayo; Uday B Kompella; Richard Longeras; Jian-Xing Ma
Nanoparticle-mediated expression of an angiogenic inhibitor ameliorates ischemia-induced retinal neovascularization and diabetes-induced retinal vascular leakage.
Diabetes 2009;58(8):1902-13.
2009: Sneha Sundaram; Chandrasekar Durairaj; Rajendra Kadam; Uday B Kompella
Luteinizing hormone-releasing hormone receptor-targeted deslorelin-docetaxel conjugate enhances efficacy of docetaxel in prostate cancer therapy.
Molecular cancer therapeutics 2009;8(6):1655-65.
2009: Esther S Kim; Chandrasekar Durairaj; Rajendra Shriram Kadam; Sung Jin Lee; Yun Mo; Dayle H Geroski; Uday B Kompella; Henry F Edelhauser
Human scleral diffusion of anticancer drugs from solution and nanoparticle formulation.
Pharmaceutical research 2009;26(5):1155-61.
2009: S R Singh; H E Grossniklaus; S J Kang; Henry F Edelhauser; B K Ambati; Uday B Kompella
Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV.
Gene therapy 2009;16(5):645-59.
2009: Chandrasekar Durairaj; Jaymin C Shah; Shruti Senapati; Uday B Kompella
Prediction of vitreal half-life based on drug physicochemical properties: quantitative structure-pharmacokinetic relationships (QSPKR).
Pharmaceutical research 2009;26(5):1236-60.
2009: Surya P Ayalasomayajula; Paul Ashton; Uday B Kompella
Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-alpha-induced angiogenesis in chick chorioallantoic membrane (CAM).
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2009;25(2):97-103.
2009: Sneha Sundaram; Shyamal K Roy; Uday B Kompella
Differential expression of LHRH-receptor in bovine nasal tissue and its role in deslorelin delivery.
Peptides 2009;30(2):351-8.
2009: Narayan P S Cheruvu; Aniruddha C Amrite; Uday B Kompella
Effect of diabetes on transscleral delivery of celecoxib.
Pharmaceutical research 2009;26(2):404-14.
2009: Adelheid Kratzer; Marlene Buchebner; Thomas Pfeifer; Tatjana M Becker; Georg Uray; Makoto Miyazaki; Shinobu Miyazaki-Anzai; Birgit Ebner; Prakash G Chandak; Rajendra Shriram Kadam; Emine Calayir; Nora Rathke; Helmut Ahammer; Branislav Radovic; Michael Trauner; Gerald Hoefler; Uday B Kompella; Guenter Fauler; Moshe Levi; Sanja Levak-Frank; Gerhard Kostner; Dagmar Kratky
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
Journal of lipid research 2009;50(2):312-26.
2009: Rajendra Shriram Kadam; Uday B Kompella
Cassette analysis of eight beta-blockers in bovine eye sclera, choroid-RPE, retina, and vitreous by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(3):253-60.
2008: Jennifer G Christie; Uday B Kompella
Ophthalmic light sensitive nanocarrier systems.
Drug discovery today 2008;13(3-4):124-34.
2008: Aniruddha C Amrite; Uday B Kompella
Celecoxib inhibits proliferation of retinal pigment epithelial and choroid-retinal endothelial cells by a cyclooxygenase-2-independent mechanism.
The Journal of pharmacology and experimental therapeutics 2008;324(2):749-58.
2008: Aniruddha C Amrite; Henry F Edelhauser; Swita R Singh; Uday B Kompella
Effect of circulation on the disposition and ocular tissue distribution of 20 nm nanoparticles after periocular administration.
Molecular vision 2008;14():150-60.
2008: Narayan P S Cheruvu; Aniruddha C Amrite; Uday B Kompella
Effect of eye pigmentation on transscleral drug delivery.
Investigative ophthalmology & visual science 2008;49(1):333-41.
2008: Aniruddha C Amrite; Henry F Edelhauser; Uday B Kompella
Modeling of corneal and retinal pharmacokinetics after periocular drug administration.
Investigative ophthalmology & visual science 2008;49(1):320-32.
2007: Uday B Kompella
Drug delivery to the back of the eye.
Archivos de la Sociedad Española de Oftalmología 2007;82(11):667-8; 669-70.
2007: Swita Raghava; Uday B Kompella
AQ4, an antitumor anthracenedione, inhibits endothelial cell proliferation and vascular endothelial growth factor secretion: implications for the therapy of ocular neovascular disorders.
European journal of pharmacology 2007;568(1-3):68-74.
2007: Pooja D Jani; Nirbhai Singh; Crystal Jenkins; Swita Raghava; Yun Mo; Shivan Amin; Uday B Kompella; Balamurali K Ambati
Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis.
Investigative ophthalmology & visual science 2007;48(5):2030-6.
2007: Peter F Kador; James Randazzo; Thomas Babb; Kavitha Koushik; Yoshihiro Takamura; Wenjun Zhu; Karen Blessing; Uday B Kompella
Topical aldose reductase inhibitor formulations for effective lens drug delivery in a rat model for sugar cataracts.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2007;23(2):116-23.
2007: Yun Mo; Micheal E Barnett; Dolores J Takemoto; Harriet Davidson; Uday B Kompella
Human serum albumin nanoparticles for efficient delivery of Cu, Zn superoxide dismutase gene.
Molecular vision 2007;13():746-57.
2007: Michelle Marra; Hovhannes J Gukasyan; Swita Raghava; Uday B Kompella
2nd Ophthalmic Drug Development and Delivery Summit.
Expert opinion on drug delivery 2007;4(1):77-85.
2006: Narayan P S Cheruvu; Uday B Kompella
Bovine and porcine transscleral solute transport: influence of lipophilicity and the Choroid-Bruch's layer.
Investigative ophthalmology & visual science 2006;47(10):4513-22.
2006: Eyal Margalit; Lance J Kugler; Matthew V Brumm; Jane L Meza; Uday B Kompella; Edith R Escobar; Gerald R Christensen
The safety of intraocular ketorolac in rabbits.
Investigative ophthalmology & visual science 2006;47(5):2093-9.
2006: Aniruddha C Amrite; Surya P Ayalasomayajula; Narayan P S Cheruvu; Uday B Kompella
Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage.
Investigative ophthalmology & visual science 2006;47(3):1149-60.
2006: Uday B Kompella; Sneha Sundaram; Swita Raghava; Edith R Escobar
Luteinizing hormone-releasing hormone agonist and transferrin functionalizations enhance nanoparticle delivery in a novel bovine ex vivo eye model.
Molecular vision 2006;12():1185-98.
2005: Aniruddha C Amrite; Uday B Kompella
Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration.
The Journal of pharmacy and pharmacology 2005;57(12):1555-63.
2005: Nagesh Bandi; Surya P Ayalasomayajula; Devender S Dhanda; Jun Iwakawa; Pi-Wan Cheng; Uday B Kompella
Intratracheal budesonide-poly(lactide-co-glycolide) microparticles reduce oxidative stress, VEGF expression, and vascular leakage in a benzo(a)pyrene-fed mouse model.
The Journal of pharmacy and pharmacology 2005;57(7):851-60.
2005: Surya P Ayalasomayajula; Uday B Kompella
Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat model.
European journal of pharmacology 2005;511(2-3):191-8.
2004: Swita Raghava; Makena Hammond; Uday B Kompella
Periocular routes for retinal drug delivery.
Expert opinion on drug delivery 2004;1(1):99-114.
2004: Surya P Ayalasomayajula; Uday B Kompella
Retinal delivery of celecoxib is several-fold higher following subconjunctival administration compared to systemic administration.
Pharmaceutical research 2004;21(10):1797-804.
2004: Nagesh Bandi; William Wei; Christopher B Roberts; Lakshmi P Kotra; Uday B Kompella
Preparation of budesonide- and indomethacin-hydroxypropyl-beta-cyclodextrin (HPBCD) complexes using a single-step, organic-solvent-free supercritical fluid process.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;23(2):159-68.
2004: Surya P Ayalasomayajula; Aniruddha C Amrite; Uday B Kompella
Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas.
European journal of pharmacology 2004;498(1-3):275-8.
2004: Kavitha Koushik; Devender S Dhanda; Narayan P S Cheruvu; Uday B Kompella
Pulmonary delivery of deslorelin: large-porous PLGA particles and HPbetaCD complexes.
Pharmaceutical research 2004;21(7):1119-26.
2004: Kavitha Koushik; Uday B Kompella
Transport of deslorelin, an LHRH agonist, is vectorial and exhibits regional variation in excised bovine nasal tissue.
The Journal of pharmacy and pharmacology 2004;56(7):861-8.
2004: Kavitha Koushik; Nagesh Bandi; Sneha Sundaram; Uday B Kompella
Evidence for LHRH-receptor expression in human airway epithelial (Calu-3) cells and its role in the transport of an LHRH agonist.
Pharmaceutical research 2004;21(6):1034-46.
2004: Kavitha Koushik; Uday B Kompella
Preparation of large porous deslorelin-PLGA microparticles with reduced residual solvent and cellular uptake using a supercritical carbon dioxide process.
Pharmaceutical research 2004;21(3):524-35.
2004: Gangadhar Sunkara; Surya P Ayalasomayajula; Cheruku S Rao; Jonathan L Vennerstrom; Jack DeRuiter; Uday B Kompella
Systemic and ocular pharmacokinetics of N-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor.
The Journal of pharmacy and pharmacology 2004;56(3):351-8.
2003: Jithan V Aukunuru; Surya P Ayalasomayajula; Uday B Kompella
Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells.
The Journal of pharmacy and pharmacology 2003;55(9):1199-206.
2003: Kavitha Koushik; Gangadhar Sunkara; Peter R Gwilt; Uday B Kompella
Pathways and kinetics of deslorelin degradation in an airway epithelial cell line (Calu-1).
Pharmaceutical research 2003;20(5):779-87.
2003: Uday B Kompella; Nagesh Bandi; Surya P Ayalasomayajula
Subconjunctival nano- and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression.
Investigative ophthalmology & visual science 2003;44(3):1192-201.
2003: Surya P Ayalasomayajula; Uday B Kompella
Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model.
European journal of pharmacology 2003;458(3):283-9.
2002: Lin Zhang; Daniel L Parsons; Christine Navarre; Uday B Kompella
Development and in-vitro evaluation of sustained release poloxamer 407 (P407) gel formulations of ceftiofur.
Journal of controlled release : official journal of the Controlled Release Society 2002;85(1-3):73-81.
2002: James G W Wenzel; K S Sree Balaji; Kavitha Koushik; Christine Navarre; Sue H Duran; C Hardin Rahe; Uday B Kompella
Pluronic F127 gel formulations of deslorelin and GnRH reduce drug degradation and sustain drug release and effect in cattle.
Journal of controlled release : official journal of the Controlled Release Society 2002;85(1-3):51-9.
2002: Surya P Ayalasomayajula; Uday B Kompella
Induction of vascular endothelial growth factor by 4-hydroxynonenal and its prevention by glutathione precursors in retinal pigment epithelial cells.
European journal of pharmacology 2002;449(3):213-20.
2002: Jithan V Aukunuru; Gangadhar Sunkara; Surya P Ayalasomayajula; Jack DeRuiter; Randall C Clark; Uday B Kompella
A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications.
Pharmaceutical research 2002;19(3):278-85.
2002: Nagesh Bandi; Uday B Kompella
Budesonide reduces multidrug resistance-associated protein 1 expression in an airway epithelial cell line (Calu-1).
European journal of pharmacology 2002;437(1-2):9-17.
2002: Todd M Martin; Nagesh Bandi; Ryan Shulz; Christopher B Roberts; Uday B Kompella
Preparation of budesonide and budesonide-PLA microparticles using supercritical fluid precipitation technology.
AAPS PharmSciTech 2002;3(3):E18.
2001: Kavitha Koushik; Nagesh Bandi; Uday B Kompella
Interaction of [D-Trp6, Des-Gly10] LHRH ethylamide and hydroxy propyl beta-cyclodextrin (HPbetaCD): thermodynamics of interaction and protection from degradation by alpha-chymotrypsin.
Pharmaceutical development and technology 2001;6(4):595-606.
2001: Gangadhar Sunkara; Uday B Kompella
Controlled release of bioactive materials--28th international symposium. Carbohydrate drug carriers: cyclodextrins and chitosans.
IDrugs : the investigational drugs journal 2001;4(9):1014-6.
2001: Nagesh Bandi; Uday B Kompella
Budesonide reduces vascular endothelial growth factor secretion and expression in airway (Calu-1) and alveolar (A549) epithelial cells.
European journal of pharmacology 2001;425(2):109-16.
2001: Jithan V Aukunuru; Gangadhar Sunkara; Nagesh Bandi; Wallace B Thoreson; Uday B Kompella
Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor.
Pharmaceutical research 2001;18(5):565-72.
2001: Uday B Kompella; Vincent H L Lee
Delivery systems for penetration enhancement of peptide and protein drugs: design considerations.
Advanced drug delivery reviews 2001;46(1-3):211-45.
2001: Uday B Kompella; Kavitha Koushik
Preparation of drug delivery systems using supercritical fluid technology.
Critical reviews in therapeutic drug carrier systems 2001;18(2):173-99.
2000: Gangadhar Sunkara; Jack DeRuiter; C R Clark; Uday B Kompella
In-vitro hydrolysis, permeability, and ocular uptake of prodrugs of N-[4-(benzoylamino)phenylsulfonyl]glycine, a novel aldose reductase inhibitor.
The Journal of pharmacy and pharmacology 2000;52(9):1113-22.
2000: Surya P Ayalasomayajula; Uday B Kompella
Drug efflux pumps: challenges and opportunities. 14-18 November 1999, New Orleans, LA, USA.
IDrugs : the investigational drugs journal 2000;3(2):148-9.
1999: Uday B Kompella; Gangadhar Sunkara; E Thomas; C R Clark; Jack DeRuiter
Rabbit corneal and conjunctival permeability of the novel aldose reductase inhibitors: N-[[4-(benzoylamino)phenyl] sulphonyl]glycines and N-benzoyl-N-phenylglycines.
The Journal of pharmacy and pharmacology 1999;51(8):921-7.
1999: Gangadhar Sunkara; Christine Navarre; Uday B Kompella
Influence of pH and temperature on kinetics of ceftiofur degradation in aqueous solutions.
The Journal of pharmacy and pharmacology 1999;51(3):249-55.
1999: Christine Navarre; L Zhang; Gangadhar Sunkara; Sue H Duran; Uday B Kompella
Ceftiofur distribution in plasma and joint fluid following regional limb injection in cattle.
Journal of veterinary pharmacology and therapeutics 1999;22(1):13-9.
1999: Uday B Kompella
Drug delivery applications of supercritical fluid technology.
IDrugs : the investigational drugs journal 1999;2(1):33-4.
1999: Uday B Kompella
Disposition of non-viral gene delivery systems and oligonucleotides.
IDrugs : the investigational drugs journal 1999;2(1):31-2.
1998: B A Dani; Uday B Kompella
Inhibition of corneal metabolism of deslorelin by EDTA and ZnCl2.
Drug development and industrial pharmacy 1998;24(1):11-7.
1998: S Mathison; Rakesh Nagilla; Uday B Kompella
Nasal route for direct delivery of solutes to the central nervous system: fact or fiction?
Journal of drug targeting 1998;5(6):415-41.
1997: Uday B Kompella; B A Dani
Metabolism of [des-Gly10, D-Trp6]LHRH ethylamide in the rabbit conjunctiva.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1997;13(2):163-70.
1996: KI Hosoya; Uday B Kompella; Kwang-Jin Kim; Vincent H L Lee
Contribution of Na(+)-glucose cotransport to the short-circuit current in the pigmented rabbit conjunctiva.
Current eye research 1996;15(4):447-51.
1996: Uday B Kompella; Kwang-Jin Kim; M H Shiue; Vincent H L Lee
Cyclic AMP modulation of active ion transport in the pigmented rabbit conjunctiva.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1996;12(3):281-7.
1996: Uday B Kompella; B A Dani
Metabolism of [Des-Gly10,D-Trp6]LHRH ethylamide in rabbit nasal tissue.
Life sciences 1996;58(24):2201-7.
1995: Uday B Kompella; Kwang-Jin Kim; M H Shiue; Vincent H L Lee
Possible existence of Na(+)-coupled amino acid transport in the pigmented rabbit conjunctiva.
Life sciences 1995;57(15):1427-31.
1993: Uday B Kompella; Kwang-Jin Kim; Vincent H L Lee
Active chloride transport in the pigmented rabbit conjunctiva.
Current eye research 1993;12(12):1041-8.
1993: Y H Lee; Uday B Kompella; Vincent H L Lee
Systemic absorption pathways of topically applied beta adrenergic antagonists in the pigmented rabbit.
Experimental eye research 1993;57(3):341-9.
1991: Vincent H L Lee; A Yamamoto; Uday B Kompella
Mucosal penetration enhancers for facilitation of peptide and protein drug absorption.
Critical reviews in therapeutic drug carrier systems 1991;8(2):91-192.