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Thomas Calzascia

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Andreas Billich; Christian Bruns; Thomas Calzascia; Andrea Isken; Bernd Kinzel; Erika Loetscher; Barbara Metzler; Matthias Mueller; Barbara Nuesslein-Hildesheim; Thomas Baumruker; Christian Beerli; Marc Bigaud; Bernadette Kleylein-Sohn
Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis.
Dirk Haubert; Daniel Kaiser; Jianping Li; Barbara Metzler; Alexander Saveliev; Esther Sutter; Victor L J Tybulewicz; Thomas Calzascia; Gisbert Weckbecker
Vav1 GEF activity is required for T cell mediated allograft rejection.
Max Warncke; Frank Kolbinger; Ratiba Touil; Nicole Balke; Thomas Calzascia; Michele Coulot; Christoph Heusser
Different adaptations of IgG effector function in human and nonhuman primates and implications for therapeutic antibody treatment.

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All Publications

2013: Andreas Billich; Christian Bruns; Thomas Calzascia; Andrea Isken; Bernd Kinzel; Erika Loetscher; Barbara Metzler; Matthias Mueller; Barbara Nuesslein-Hildesheim; Thomas Baumruker; Christian Beerli; Marc Bigaud; Bernadette Kleylein-Sohn
Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis.
PloS one 2013;8(3):e59630.
2012: Dirk Haubert; Daniel Kaiser; Jianping Li; Barbara Metzler; Alexander Saveliev; Esther Sutter; Victor L J Tybulewicz; Thomas Calzascia; Gisbert Weckbecker
Vav1 GEF activity is required for T cell mediated allograft rejection.
Transplant immunology 2012;26(4):212-9.
2012: Max Warncke; Frank Kolbinger; Ratiba Touil; Nicole Balke; Thomas Calzascia; Michele Coulot; Christoph Heusser
Different adaptations of IgG effector function in human and nonhuman primates and implications for therapeutic antibody treatment.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(9):4405-11.
2012: Chao Wang; Feng Yun Yue; Nasra Aidarus; Thanuja Ambagala; Erika Benko; Nicole F Bernard; Thomas Calzascia; Alisha R Elford; R Brad Jones; Kim S Kawamura; Colin M Kovacs; Elisabeth Kremmer; Philipp A Lang; Gloria H Y Lin; Ann J McPherson; Pamela S Ohashi; Mario A Ostrowski; Marc Pellegrini; Jean-Pierre Routy; Cecile Tremblay; Tania H Watts
Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection.
The Journal of experimental medicine 2012;209(1):77-91.
2011: Marc Pellegrini; Thomas Calzascia; Jesse G Toe; Simon P Preston; Amy E Lin; Alisha R Elford; Arda Shahinian; Philipp A Lang; Karl S Lang; Michel MORRE; Brigitte Assouline; Katharina Lahl; Tim D. Sparwasser; Thomas F Tedder; Ji-Hye Paik; Ronald A DePinho; Sameh Basta; Pamela S Ohashi; Tak W Mak
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
Cell 2011;144(4):601-13.
2009: Marc Pellegrini; Thomas Calzascia; Alisha R Elford; Arda Shahinian; Amy E Lin; Dilan Dissanayake; Salim Dhanji; Linh T Nguyen; Matthew A Gronski; Michel MORRE; Brigitte Assouline; Katharina Lahl; Tim D. Sparwasser; Pamela S Ohashi; Tak W Mak
Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.
Nature medicine 2009;15(5):528-36.
2008: Thomas Calzascia; Jacelyn M S Loh; Wilma Di Berardino-Besson; Frédérick Masson; Philippe Guillaume; Karim Burkhardt; Pedro L Herrera; Pierre-Yves Dietrich; Paul R Walker
Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes.
Glia 2008;56(15):1625-36.
2008: Philipp A Lang; Claudio Contaldo; Panco Georgiev; Ashraf Mohammad El-Badry; Mike Recher; Michael O Kurrer; Luisa Cervantes-Barragan; Burkhard Ludewig; Thomas Calzascia; Beatrice Bolinger; Doron Merkler; Bernhard Odermatt; Michael Bader; Rolf Graf; Pierre-Alain Clavien; Ahmed N Hegazy; Max Löhning; Nicola L Harris; Pamela S Ohashi; Hans Hengartner; Rolf M Zinkernagel; Karl S Lang
Aggravation of viral hepatitis by platelet-derived serotonin.
Nature medicine 2008;14(7):756-61.
2008: Elizabeth Lye; Salim Dhanji; Thomas Calzascia; Alisha R Elford; Pamela S Ohashi
IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses.
European journal of immunology 2008;38(3):870-6.
2008: Thomas Calzascia; Marc Pellegrini; Albert Lin; Kristine M Garza; Alisha R Elford; Arda Shahinian; Pamela S Ohashi; Tak W Mak
CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):2999-3004.
2007: Thomas Calzascia; Marc Pellegrini; Håkan Hall; Laurent Sabbagh; Nobuyuki Ono; Alisha R Elford; Tak W Mak; Pamela S Ohashi
TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.
The Journal of clinical investigation 2007;117(12):3833-45.
2007: Frédérick Masson; Thomas Calzascia; Wilma Di Berardino-Besson; Nicolas de Tribolet; Pierre-Yves Dietrich; Paul R Walker
Brain microenvironment promotes the final functional maturation of tumor-specific effector CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):845-53.
2006: Nobutaka Suzuki; Shinobu Suzuki; Douglas G Millar; Midori Unno; Hiromitsu Hara; Thomas Calzascia; Sho Yamasaki; Tadashi Yokosuka; Nien-Jung Chen; Alisha R Elford; Jun-Ichiro Suzuki; Arata Takeuchi; Christine Mirtsos; Denis Bouchard; Pamela S Ohashi; Wen-Chen Yeh; Takashi Saito
A critical role for the innate immune signaling molecule IRAK-4 in T cell activation.
Science (New York, N.Y.) 2006;311(5769):1927-32.
2005: Zhenyue Hao; Gordon S Duncan; Chia-Che Chang; Andrew Elia; Min Fang; Andrew Wakeham; Hitoshi Okada; Thomas Calzascia; YingJu Jang; Annick You-Ten; Wen-Chen Yeh; Pamela S Ohashi; Xiaodong Wang; Tak W Mak
Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis.
Cell 2005;121(4):579-91.
2005: Thomas Calzascia; Frédérick Masson; Wilma Di Berardino-Besson; Emmanuel Contassot; Rick Wilmotte; michel AURRAND-LIONS; Curzio Rüegg; Pierre-Yves Dietrich; Paul R Walker
Homing phenotypes of tumor-specific CD8 T cells are predetermined at the tumor site by crosspresenting APCs.
Immunity 2005;22(2):175-84.
2004: Shohreh Zarei; Shahnaz Abraham; Jean-François Arrighi; Olivier Haller; Thomas Calzascia; Paul R Walker; Thomas M Kündig; Conrad Hauser; vincent piguet
Lentiviral transduction of dendritic cells confers protective antiviral immunity in vivo.
Journal of virology 2004;78(14):7843-5.
2003: Shohreh Zarei; Jean-François Arrighi; Gioele Ongaro; Thomas Calzascia; Olivier Haller; Christophe P Frossard; vincent piguet; Paul R Walker; Conrad Hauser
Efficient induction of CD8 T-associated immune protection by vaccination with mRNA transfected dendritic cells.
The Journal of investigative dermatology 2003;121(4):745-50.
2003: Thomas Calzascia; Wilma Di Berardino-Besson; Rick Wilmotte; Frédérick Masson; Nicolas de Tribolet; Pierre-Yves Dietrich; Paul R Walker
Cutting edge: cross-presentation as a mechanism for efficient recruitment of tumor-specific CTL to the brain.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2187-91.
2003: Paul R Walker; Thomas Calzascia; Nicolas de Tribolet; Pierre-Yves Dietrich
T-cell immune responses in the brain and their relevance for cerebral malignancies.
Brain research. Brain research reviews 2003;42(2):97-122.
2002: Paul R Walker; Thomas Calzascia; Pierre-Yves Dietrich
All in the head: obstacles for immune rejection of brain tumours.
Immunology 2002;107(1):28-38.
2000: Paul R Walker; Thomas Calzascia; Valerie Schnuriger; David Chalmers; Philippe Saas; Pierre-Yves Dietrich
Loss of Fas (CD95/APO-1) expression by antigen-specific cytotoxic T cells is reversed by inhibiting DNA methylation.
Cellular immunology 2000;206(1):51-8.
2000: Paul R Walker; Thomas Calzascia; Valerie Schnuriger; N Scamuffa; Philippe Saas; Nicolas de Tribolet; Pierre-Yves Dietrich
The brain parenchyma is permissive for full antitumor CTL effector function, even in the absence of CD4 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3128-35.