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Andras Nagy

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Zhijie Li; Iacovos P Michael; Andras Nagy; Dongxia Zhou; James M Rini
Simple piggyBac transposon-based mammalian cell expression system for inducible protein production.
Lieven Haenebalcke; Sonia Bartunkova; Jinke D'Hont; Pieterjan Dierickx; Steven Goossens; Katharina Haigh; Tino Hochepied; Andras Nagy; Dagmar Wirth; Jody J Haigh
The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation.
Hoon-Ki Sung; Kristina Nagy; Seana Mary Lunney Nelson; Jin Gyoon Park; Tony Pawson; Joe Eun Son; S Lee Adamson; Yunui Bae; Soojeong Choi; Rebecca Cowling; Kyung-Oh Doh; Gou Young Koh; Iacovos Michael; Andras Nagy
Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis.

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All Publications

2013: Zhijie Li; Iacovos P Michael; Andras Nagy; Dongxia Zhou; James M Rini
Simple piggyBac transposon-based mammalian cell expression system for inducible protein production.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(13):5004-9.
2013: Lieven Haenebalcke; Sonia Bartunkova; Jinke D'Hont; Pieterjan Dierickx; Steven Goossens; Katharina Haigh; Tino Hochepied; Andras Nagy; Dagmar Wirth; Jody J Haigh
The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation.
Cell reports 2013;3(2):335-41.
2013: Hoon-Ki Sung; Kristina Nagy; Seana Mary Lunney Nelson; Jin Gyoon Park; Tony Pawson; Joe Eun Son; S Lee Adamson; Yunui Bae; Soojeong Choi; Rebecca Cowling; Kyung-Oh Doh; Gou Young Koh; Iacovos Michael; Andras Nagy
Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis.
Cell metabolism 2013;17(1):61-72.
2012: Kento Onishi; Peter D Tonge; Andras Nagy; Peter W Zandstra
Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK-STAT signaling.
Integrative biology : quantitative biosciences from nano to macro 2012;4(11):1367-76.
2012: Jing Jin; Nina Jones; Dontscho Kerjaschki; Chengjin Li; Andras Nagy; Tony Pawson; I George Fantus; Napoleone Ferrara; Hans-Peter Gerber; Marie Jeansson; Masabumi Shibuya; Karen Sison; Hoon-Ki Sung; Ruijun Tian; Monika Tucholska; Monika Wnuk; Cunjie Zhang; Susan E Quaggin
Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.
Cell 2012;151(2):384-99.
2012: David A Fluri; Andras Nagy; Nika Shakiba; Shreya Shukla; Hannah Song; Peter D Tonge; Ricardo P Baptista; Geoffrey Clarke; Peter W Zandstra
Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures.
Nature methods 2012;9(5):509-16.
2012: Monica Teta; Gabrielle Wong; Thomas Andl; Yeon Sook Choi; Mark M W Chong; Dan R Littman; Andras Nagy; Tishina Okegbe; John T Seykora; Oliver H Tam; Sarah E Millar
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin.
Development (Cambridge, England) 2012;139(8):1405-16.
2012: Iacovos Michael; Claudio Monetti; Siamak Agha-Mohammadi; Takeshi Baba; Anthony C Chiu; Koichiro Nishino; Hoon-Ki Sung; Knut Woltjen; Puzheng Zhang; Andras Nagy
Highly efficient site-specific transgenesis in cancer cell lines.
Molecular cancer 2012;11():89.
2011: Koichiro Nishino; Shun Sato; Yoshikazu Arai; Naoko Hattori; Andras Nagy; Satoshi Tanaka; Kunio Shiota
Non-CpG methylation occurs in the regulatory region of the Sry gene.
The Journal of reproduction and development 2011;57(5):586-93.
2011: Mathieu Gabut; Timothy R Hughes; Esteban O Mazzoni; Andras Nagy; Stephane Nedelec; David O'Hanlon; Qun Pan; Payman Samavarchi-Tehrani; Valentina Slobodeniuc; Hoon-Ki Sung; Shaheynoor Talukder; Xinchen Wang; Hynek Wichterle; Knut Woltjen; Jeffrey L Wrana; Peter W Zandstra; Manuel Alvarez; Benjamin J Blencowe
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
Cell 2011;147(1):132-46.
2011: Kristina Nagy; Lawrence Charles Smith; Hoon-Ki Sung; Patrick Vincent; Knut Woltjen; Puzheng Zhang; Siamak Agha-Mohammadi; Simon Laflamme; Iacovos Michael; Claudio Monetti; Andras Nagy
Induced pluripotent stem cell lines derived from equine fibroblasts.
Stem cell reviews 2011;7(3):693-702.
2011: Paria Mohseni; Amanda J Murphy; John E Eriksson; John Georgiou; Mark Henkelman; Christine L Laliberte; Hanna-Mari Pallari; Susan E Quaggin; Hoon-Ki Sung; Paul S Thorner; Gang Xie; Andras Nagy
Nestin is not essential for development of the CNS but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(32):11547-52.
2011: Hironori Adachi; Tatsuya Kondo; Gou Young Koh; Andras Nagy; Yuichi Oike; Eiichi Araki
Angptl4 deficiency decreases serum triglyceride levels in low-density lipoprotein receptor knockout mice and streptozotocin-induced diabetic mice.
Biochemical and biophysical research communications 2011;409(2):177-80.
2011: S M I Hussein; K Nagy; Andras Nagy
Human induced pluripotent stem cells: the past, present, and future.
Clinical pharmacology and therapeutics 2011;89(5):741-5.
2011: Claudio Monetti; Koichiro Nishino; Steffen Biechele; Puzheng Zhang; Takeshi Baba; Knut Woltjen; Andras Nagy
PhiC31 integrase facilitates genetic approaches combining multiple recombinases.
Methods (San Diego, Calif.) 2011;53(4):380-5.
2011: Knut Woltjen; Riikka Hämäläinen; Mark Kibschull; Maria Mileikovsky; Andras Nagy
Transgene-free production of pluripotent stem cells using piggyBac transposons.
Methods in molecular biology (Clifton, N.J.) 2011;767():87-103.
2011: Mark Kibschull; Maria Mileikovsky; Iacovos Michael; Stephen J Lye; Andras Nagy
Human embryonic fibroblasts support single cell enzymatic expansion of human embryonic stem cells in xeno-free cultures.
Stem cell research 2011;6(1):70-82.
2010: Peter Dennis Tonge; Andras Nagy
Extinction of Xist improves cloning.
Cell stem cell 2010;7(5):550-2.
2010: Bo Hai; Zhenhua Yang; Sarah E Millar; Yeon Sook Choi; Makoto Mark Taketo; Andras Nagy; Fei Liu
Wnt/β-catenin signaling regulates postnatal development and regeneration of the salivary gland.
Stem cells and development 2010;19(11):1793-801.
2010: Benjamin Drogat; Joanna Kalucka; Laura Gutiérrez; Hamida Hammad; Steven Goossens; Morvarid Farhang Ghahremani; Sonia Bartunkova; Katharina Haigh; Kim Deswarte; Omar Nyabi; Michael Naessens; Napoleone Ferrara; Ursula Klingmüller; Bart N Lambrecht; Andras Nagy; Sjaak Philipsen; Jody J Haigh
Vegf regulates embryonic erythroid development through Gata1 modulation.
Blood 2010;116(12):2141-51.
2010: F Liu; S Dangaria; Thomas Andl; Yulong Zhang; A C Wright; M Damek-Poprawa; Stefano Piccolo; Andras Nagy; Makoto M Taketo; Tom Diekwisch; S O Akintoye; Sarah E Millar
beta-Catenin initiates tooth neogenesis in adult rodent incisors.
Journal of dental research 2010;89(9):909-14.
2010: Young Jun Koh; Hak-Zoo Kim; Seong-Ik Hwang; Jeung Eun Lee; Nuri Oh; Keehoon Jung; Minah Kim; Kyung Eun Kim; Homin Kim; Nam-Kyu Lim; Choon-Ju Jeon; Gyun Min Lee; Byeong Hwa Jeon; Do-Hyun Nam; Hoon-Ki Sung; Andras Nagy; Ook Joon Yoo; Gou Young Koh
Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage.
Cancer cell 2010;18(2):171-84.
2010: Steve Tardif; Michael D Wilson; Rebecca Wagner; Peter Hunt; Marina Gertsenstein; Andras Nagy; Corrinne Lobe; Ben F Koop; Daniel M Hardy
Zonadhesin is essential for species specificity of sperm adhesion to the egg zona pellucida.
The Journal of biological chemistry 2010;285(32):24863-70.
2010: Andras Nagy; Marina Gertsenstein; Kristina Vintersten; Richard Behringer
In vitro screen to obtain widespread, transgenic expression in the mouse.
Cold Spring Harbor protocols 2010;2010(8):pdb.prot4408.
2010: Leigh Coultas; Erica Nieuwenhuis; Gregory A Anderson; Jorge Cabezas; Andras Nagy; R Mark Henkelman; Chi-Chung Hui; Janet Rossant
Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms.
Blood 2010;116(4):653-60.
2010: Payman Samavarchi-Tehrani; Azadeh Golipour; Laurent David; Hoon-Ki Sung; Tobias A Beyer; Alessandro Datti; Knut Woltjen; Andras Nagy; Jeffrey L Wrana
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.
Cell stem cell 2010;7(1):64-77.
2010: Andras Nagy; Marina Gertsenstein; Kristina Vintersten; Richard Behringer
Thawing embryonic stem (ES) cells from a 96-well plate.
Cold Spring Harbor protocols 2010;2010(7):pdb.prot4412.
2010: Andras Nagy; Susan E Quaggin
Stem cell therapy for the kidney: a cautionary tale.
Journal of the American Society of Nephrology : JASN 2010;21(7):1070-2.
2010: Hoon-Ki Sung; Iacovos Michael; Andras Nagy
Multifaceted role of vascular endothelial growth factor signaling in adult tissue physiology: an emerging concept with clinical implications.
Current opinion in hematology 2010;17(3):206-12.
2010: Nazish Ahmed; Drew W Taylor; Jay Wunder; Andras Nagy; Allan E Gross; Rita A Kandel
Passaged human chondrocytes accumulate extracellular matrix when induced by bovine chondrocytes.
Journal of tissue engineering and regenerative medicine 2010;4(3):233-41.
2010: Andras Nagy
Visualizing fetal mouse vasculature by India ink injection.
Cold Spring Harbor protocols 2010;2010(2):pdb.prot5371.
2010: Laura M Vecchiarelli-Federico; David Cervi; Mehran Haeri; Yanmei Li; Andras Nagy; Yaacov Ben David
Vascular endothelial growth factor--a positive and negative regulator of tumor growth.
Cancer research 2010;70(3):863-7.
2010: Christa Maes; Steven Goossens; Sonia Bartunkova; Benjamin Drogat; Lieve Coenegrachts; Ingrid Stockmans; Karen Moermans; Omar Nyabi; Katharina Haigh; Michael Naessens; Lieven Haenebalcke; Jan P Tuckermann; Marc Tjwa; Peter Carmeliet; Vice Mandic; Jean-Pierre David; Axel Behrens; Andras Nagy; Geert Carmeliet; Jody J Haigh
Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.
The EMBO journal 2010;29(2):424-41.
2010: Andras Nagy; Kristina Nagy; Marina Gertsenstein
Production of mouse chimeras by aggregating pluripotent stem cells with embryos.
Methods in enzymology 2010;476():123-49.
2010: Marina Gertsenstein; Lauryl M J Nutter; Tammy Reid; Monica Pereira; William L Stanford; Janet Rossant; Andras Nagy
Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos.
PloS one 2010;5(6):e11260.
2010: Andras Nagy; Kristina Nagy
The mysteries of induced pluripotency: where will they lead?
Nature methods 2010;7(1):22-4.
2010: Keli Xu; Erica Nieuwenhuis; Brenda L Cohen; Wei Wang; Angelo J Canty; Jayne S Danska; Leigh Coultas; Janet Rossant; Megan Y J Wu; Tino D Piscione; Andras Nagy; Achim Gossler; Geoff G Hicks; Chi-Chung Hui; R Mark Henkelman; Lisa X Yu; John G Sled; Thomas Gridley; Sean E Egan
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.
American journal of physiology. Lung cellular and molecular physiology 2010;298(1):L45-56.
2009: D Giuffrida; I M Rogers; Andras Nagy; Aldo E Calogero; T J Brown; Robert F Casper
Human embryonic stem cells secrete soluble factors that inhibit cancer cell growth.
Cell proliferation 2009;42(6):788-98.
2009: Louis Lefebvre; Lynn Mar; Aaron Bogutz; Rosemary Oh-McGinnis; Mohammad A Mandegar; Jana Paderova; Marina Gertsenstein; Jeremy A Squire; Andras Nagy
The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region.
Human molecular genetics 2009;18(22):4255-67.
2009: Maren Godmann; Isabella Gashaw; Jonathan P Katz; Andras Nagy; Klaus kaestner; Rüdiger Behr
Krüppel-like factor 4, a "pluripotency transcription factor" highly expressed in male postmeiotic germ cells, is dispensable for spermatogenesis in the mouse.
Mechanisms of development 2009;126(8-9):650-64.
2009: Andras Nagy; Marina Gertsenstein; Kristina Vintersten; Richard Behringer
Counting chromosomes in embryonic stem (ES) cells.
Cold Spring Harbor protocols 2009;2009(6):pdb.prot4404.
2009: Zoltán Ivics; Meng Amy Li; Lajos Mátés; Jef Boeke; Andras Nagy; Allan Bradley; Zsuzsanna Izsvák
Transposon-mediated genome manipulation in vertebrates.
Nature methods 2009;6(6):415-22.
2009: Andras Nagy
Interview: Virus-free induction of induced pluripotent stem cells.
Regenerative medicine 2009;4(3):351-2.
2009: Knut Woltjen; Iacovos Michael; Paria Mohseni; Ridham Desai; Maria Mileikovsky; Riikka Hämäläinen; Rebecca Cowling; Wei Wang; Pentao Liu; Marina Gertsenstein; Keisuke Kaji; Hoon-Ki Sung; Andras Nagy
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells.
Nature 2009;458(7239):766-70.
2009: Omar Nyabi; Michael Naessens; Katharina Haigh; Agnieszka Gembarska; Steven Goossens; Marion Maetens; Sarah De Clercq; Benjamin Drogat; Lieven Haenebalcke; Sonia Bartunkova; Ilse De Vos; Bram De Craene; Mansour Karimi; Geert Berx; Andras Nagy; Pierre Hilson; Jean-Christophe Marine; Jody J Haigh
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells.
Nucleic acids research 2009;37(7):e55.
2009: James Ellis; Benoit G Bruneau; Gordon Keller; Ihor R Lemischka; Andras Nagy; Janet Rossant; Deepak Srivastava; Peter W Zandstra; William L Stanford
Alternative induced pluripotent stem cell characterization criteria for in vitro applications.
Cell stem cell 2009;4(3):198-9; author reply 202.
2009: Andras Nagy; Marina Gertsenstein; Kristina Vintersten; Richard Behringer
Alizarin red staining of post-natal bone in mouse.
Cold Spring Harbor protocols 2009;2009(3):pdb.prot5171.
2009: Andras Nagy; Marina Gertsenstein; Kristina Vintersten; Richard Behringer
Alcian blue staining of the mouse fetal cartilaginous skeleton.
Cold Spring Harbor protocols 2009;2009(3):pdb.prot5169.
2009: Nazish Ahmed; Lu Gan; Andras Nagy; Jianing Zheng; Chen Wang; Rita A Kandel
Cartilage tissue formation using redifferentiated passaged chondrocytes in vitro.
Tissue engineering. Part A 2009;15(3):665-73.
2009: Hironori Adachi; Yukio Fujiwara; Tatsuya Kondo; Takeshi Nishikawa; Rei Ogawa; Takeshi Matsumura; Norio Ishii; Ryoji Nagai; Keishi Miyata; Mitsuhisa Tabata; Hiroyuki Motoshima; Noboru Furukawa; Kaku Tsuruzoe; Junji Kawashima; Motohiro Takeya; Shizuya Yamashita; Gou Young Koh; Andras Nagy; Toshio Suda; Yuichi Oike; Eiichi Araki
Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis.
Biochemical and biophysical research communications 2009;379(4):806-11.
2009: Nobuko Yamanaka; Christine J Wong; Marina Gertsenstein; Robert F Casper; Andras Nagy; Ian M Rogers
Bone marrow transplantation results in human donor blood cells acquiring and displaying mouse recipient class I MHC and CD45 antigens on their surface.
PloS one 2009;4(12):e8489.
2009: Mika Tanaka; Anna-Katerina Hadjantonakis; Kristina Vintersten; Andras Nagy
Aggregation chimeras: combining ES cells, diploid, and tetraploid embryos.
Methods in molecular biology (Clifton, N.J.) 2009;530():287-309.
2009: Andras Nagy; Lynn Mar; Graham Watts
Creation and use of a cre recombinase transgenic database.
Methods in molecular biology (Clifton, N.J.) 2009;530():365-78.
2008: Kelly A Purpura; Sophia George; Stephen M Dang; Kyunghee Choi; Andras Nagy; Peter W Zandstra
Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner.
Stem cells (Dayton, Ohio) 2008;26(11):2832-42.
2008: Cheryle A Séguin; Jonathan S Draper; Andras Nagy; Janet Rossant
Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells.
Cell stem cell 2008;3(2):182-95.
2008: Kristin Alberti; Ryan E Davey; Kento Onishi; Sophia George; Katrin Salchert; F Philipp Seib; Martin Bornhäuser; Tilo Pompe; Andras Nagy; Carsten Werner; Peter W Zandstra
Functional immobilization of signaling proteins enables control of stem cell fate.
Nature methods 2008;5(7):645-50.
2008: Yuhang Zhang; Thomas Andl; Steven H Yang; Monica Teta; Fei Liu; John T Seykora; John W Tobias; Stefano Piccolo; Ruth Schmidt-Ullrich; Andras Nagy; Makoto M Taketo; Andrzej Dlugosz; Sarah E Millar
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.
Development (Cambridge, England) 2008;135(12):2161-72.
2008: Cynthia B Cohen; Bruce Brandhorst; Andras Nagy; Arthur Leader; Bernard Dickens; Rosario M Isasi; Donald Evans; Bartha Maria Knoppers
The use of fresh embryos in stem cell research: ethical and policy issues.
Cell stem cell 2008;2(5):416-21.
2008: Michael D O'Connor; Melanie D Kardel; Ioulia Iosfina; David Youssef; Min Lu; Michael M Li; Suzanne Vercauteren; Andras Nagy; Connie J Eaves
Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells.
Stem cells (Dayton, Ohio) 2008;26(5):1109-16.
2008: Karolina M Kolodziejska; M H Noyan-Ashraf; Andras Nagy; Andrea Bacon; Jon Frampton; Hong-Bo Xin; Michael I Kotlikoff; Mansoor Husain
c-Myb-dependent smooth muscle cell differentiation.
Circulation research 2008;102(5):554-61.
2008: Michael D Wilson; Diana Wang; Rebecca Wagner; Hilde Breyssens; Marina Gertsenstein; Corrinne Lobe; Xin Lu; Andras Nagy; Robert D Burke; Ben F Koop; Perry L Howard
ARS2 is a conserved eukaryotic gene essential for early mammalian development.
Molecular and cellular biology 2008;28(5):1503-14.
2008: Rosemary Oh; Rita Ho; Lynn Mar; Marina Gertsenstein; Jana Paderova; John Hsien; Jeremy A Squire; Michael J Higgins; Andras Nagy; Louis Lefebvre
Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.
Molecular and cellular biology 2008;28(3):1092-103.
2008: Anna-Katerina Hadjantonakis; Melinda Pirity; Andras Nagy
Cre recombinase mediated alterations of the mouse genome using embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2008;461():111-32.
2007: Raheem Peerani; Balaji M Rao; Céline Bauwens; Ting Yin; Geoffrey A Wood; Andras Nagy; Eugenia Kumacheva; Peter W Zandstra
Niche-mediated control of human embryonic stem cell self-renewal and differentiation.
The EMBO journal 2007;26(22):4744-55.
2007: Katrina MacAulay; Bradley Doble; Satish Patel; Tanya Hansotia; Elaine M Sinclair; Daniel J Drucker; Andras Nagy; James R Woodgett
Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism.
Cell metabolism 2007;6(4):329-37.
2007: Sunyoung Lee; Tom T Chen; Chad L Barber; Maria C Jordan; Jared Murdock; Sharina Desai; Napoleone Ferrara; Andras Nagy; Kenneth P Roos; M Luisa Iruela-Arispe
Autocrine VEGF signaling is required for vascular homeostasis.
Cell 2007;130(4):691-703.
2007: Oluseun Adewumi; Behrouz Aflatoonian; Lars Ahrlund-Richter; Michal Amit; Peter W Andrews; Gemma Beighton; Paul A Bello; Nissim Benvenisty; Lorraine S Berry; Simon Bevan; Barak Blum; Justin Brooking; Kevin Gang Chen; Andre B H Choo; Gary Churchill; Marie Corbel; Ivan Damjanov; Jon S Draper; Petr Dvorak; Katarina Emanuelsson; Roland A Fleck; Angela Ford; Karin Gertow; Marina Gertsenstein; paul Gokhale; Rebecca S Hamilton; Ales Hampl; Lyn E Healy; Outi Hovatta; Johan Hyllner; Marta P Imreh; Joseph Itskovitz-Eldor; Jamie Jackson; Jacqueline L Johnson; Mark Jones; Kehkooi Kee; Benjamin L King; Barbara B Knowles; Majlinda Lako; Franck Lebrin; Barbara S Mallon; Daisy Manning; Yoav Mayshar; Ronald D G McKay; Anna E Michalska; Milla Mikkola; Masha Mileikovsky; Stephen L Minger; Harry D Moore; Christine L Mummery; Andras Nagy; Norio Nakatsuji; Carmel M O'Brien; Steve K W Oh; Cia Olsson; Timo Otonkoski; Kye-Yoon Park; Passier Robert; Hema Patel; Minal Patel; Roger Pedersen; Martin F Pera; Marian S Piekarczyk; Renee A Reijo Pera; Benjamin E Reubinoff; Allan J Robins; Janet Rossant; Peter Rugg-Gunn; Thomas C Schulz; Henrik Semb; Eric S Sherrer; Henrike Siemen; Glyn N Stacey; Miodrag Stojkovic; Hirofumi Suemori; Jin Szatkiewicz; Tikva Turetsky; Timo Tuuri; Stieneke van den Brink; Kristina Vintersten; Sanna Vuoristo; Dorien Ward; Thomas A Weaver; Lesley A Young; Weidong Zhang
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nature biotechnology 2007;25(7):803-16.
2007: Sophia George; Marina Gertsenstein; Kristina Vintersten; Ella Korets-Smith; John Murphy; Mary E Stevens; Jody J Haigh; Andras Nagy
Developmental and adult phenotyping directly from mutant embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4455-60.
2007: Dave Cervi; Yuval Shaked; Mehran Haeri; Tatiana Usenko; Christina Lee; Jody J Haigh; Andras Nagy; Robert S Kerbel; Eitan Yefenof; Yaacov Ben David
Enhanced natural-killer cell and erythropoietic activities in VEGF-A-overexpressing mice delay F-MuLV-induced erythroleukemia.
Blood 2007;109(5):2139-46.
2007: J S Draper; Andras Nagy
Improved embryonic stem cell technologies.
Handbook of experimental pharmacology 2007;(178):107-28.
2006: Kotaro Takeda; Vivienne C Ho; Hiromi Takeda; Li-Juan Duan; Andras Nagy; Guo-Hua Fong
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
Molecular and cellular biology 2006;26(22):8336-46.
2006: T Amano; M Gertsenstein; Andras Nagy; H Kurihara; Hiroetsu Suzuki
Nuclear transfer reprogramming does not improve the low developmental potency of embryonic stem cells induced by long-term culture.
Reproduction (Cambridge, England) 2006;132(2):257-63.
2006: Tamaki Wada; Jody J Haigh; Masatsugu Ema; Seiji Hitoshi; Radha Chaddah; Janet Rossant; Andras Nagy; Derek van der Kooy
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(25):6803-12.
2006: Vera Eremina; Shiying Cui; Hanspeter Gerber; Napoleone Ferrara; Jody J Haigh; Andras Nagy; Masatsugu Ema; Janet Rossant; Serge Jothy; Jeffrey H Miner; Susan E Quaggin
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.
Journal of the American Society of Nephrology : JASN 2006;17(3):724-35.
2006: Andras Nagy; Kristina Vintersten
Murine embryonic stem cells.
Methods in enzymology 2006;418():3-21.
2005: Jing Chen; Peter C Reifsnyder; Felix Scheuplein; William H Schott; Maria Mileikovsky; Sharon Soodeen-Karamath; Andras Nagy; Michael H Dosch; James Ellis; Friedrich Koch-Nolte; Edward H Leiter
"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(10):775-83.
2005: Simon J Bubnic; Andras Nagy; Armand Keating
Donor hematopoietic cells from transgenic mice that express GFP are immunogenic in immunocompetent recipients.
Hematology (Amsterdam, Netherlands) 2005;10(4):289-95.
2005: Jun K Takeuchi; Maria Mileikovskaia; Kazuko Koshiba-Takeuchi; Analeah B Heidt; Alessandro Mori; Eric P Arruda; Marina Gertsenstein; Romain Georges; Lorinda Davidson; Rong Mo; Chi-Chung Hui; R Mark Henkelman; Mona Nemer; Brian L Black; Andras Nagy; Benoit G Bruneau
Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development.
Development (Cambridge, England) 2005;132(10):2463-74.
2005: Denhí Schnabel; Laura Ramírez; Marina Gertsenstein; Andras Nagy; Hilda Lomelí
Ectopic expression of KitD814Y in spermatids of transgenic mice, interferes with sperm morphogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(1):29-40.
2005: Edit Várkondi; Ferenc Gyory; Andras Nagy; István Kiss; István Ember; László Kozma
Oncogene amplification and overexpression of oncoproteins in thyroid papillary cancer.
In vivo (Athens, Greece) 2005;19(2):465-70.
2005: Gusztav Belteki; Jody J Haigh; Nikolett Kabacs; Katharina Haigh; Karen Sison; Frank Costantini; Jeff Whitsett; Susan E Quaggin; Andras Nagy
Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.
Nucleic acids research 2005;33(5):e51.
2005: Verónica Ramos-Mejía; Diana Escalante-Alcalde; Tilo Kunath; Laura Ramírez; Marina Gertsenstein; Andras Nagy; Hilda Lomelí
Phenotypic analyses of mouse embryos with ubiquitous expression of Oct4: effects on mid-hindbrain patterning and gene expression.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;232(1):180-90.
2004: Kristina Vintersten; Claudio Monetti; Marina Gertsenstein; Puzheng Zhang; Lajos Laszlo; Steffen Biechele; Andras Nagy
Mouse in red: red fluorescent protein expression in mouse ES cells, embryos, and adult animals.
Genesis (New York, N.Y. : 2000) 2004;40(4):241-6.
2004: Quenten Schwarz; Chenghua Gu; Hajime Fujisawa; Kimberly Sabelko; Marina Gertsenstein; Andras Nagy; Masahiko Taniguchi; Alex L Kolodkin; David D Ginty; David T Shima; Christiana Ruhrberg
Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve.
Genes & development 2004;18(22):2822-34.
2004: Fredrik Bäckhed; Hao Ding; Ting Wang; Lora V Hooper; Gou Young Koh; Andras Nagy; Clay F Semenkovich; Jeffrey I Gordon
The gut microbiota as an environmental factor that regulates fat storage.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15718-23.
2004: Ella Korets-Smith; Lothar Lindemann; Kerry Lee Tucker; Caoyang Jiang; Nikolett Kabacs; Gusztav Belteki; Jody J Haigh; Marina Gertsenstein; Andras Nagy
Cre recombinase specificity defined by the tau locus.
Genesis (New York, N.Y. : 2000) 2004;40(3):131-8.
2004: James Kehler; Elena Tolkunova; Birgit Koschorz; Maurizio Pesce; Luca Gentile; Michele Boiani; Hilda Lomelí; Andras Nagy; K John McLaughlin; Hans R Schöler; Alexey Tomilin
Oct4 is required for primordial germ cell survival.
EMBO reports 2004;5(11):1078-83.
2004: Hao Ding; Xiaoli Wu; Hans Boström; Injune Kim; Nicole Wong; Bonny Tsoi; Meredith O'Rourke; Gou Young Koh; Philippe Soriano; Christer Betsholtz; Thomas Hart; Mary L Marazita; L Leigh Field; Patrick P L Tam; Andras Nagy
A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling.
Nature genetics 2004;36(10):1111-6.
2004: Christopher P Austin; James F Battey; Allan Bradley; Maja Bucan; Mario R Capecchi; Francis S Collins; William F Dove; Geoffrey Duyk; Susan Dymecki; Janan T Eppig; Franziska B Grieder; Nathaniel Heintz; Geoff Hicks; Thomas R Insel; Alexandra L Joyner; Beverly H Koller; K C Kent Lloyd; Terry Magnuson; Mark W Moore; Andras Nagy; Jonathan D Pollock; Allen D Roses; Arthur T Sands; Brian Seed; William C Skarnes; Jay Snoddy; Philippe Soriano; David J Stewart; Francis Stewart; Bruce Stillman; Harold Varmus; Lyuba Varticovski; Inder M Verma; Thomas F Vogt; Harald von Melchner; Jan Witkowski; Richard P Woychik; Wolfgang Wurst; George D Yancopoulos; Stephen G Young; Brian Zambrowicz
The knockout mouse project.
Nature genetics 2004;36(9):921-4.
2004: Hao Ding; Mike Schertzer; Xiaoli Wu; Marina Gertsenstein; Sara Selig; Makoto Kammori; Reza Pourvali; Steven Poon; Irma Vulto; Liz Chavez; Patrick P L Tam; Andras Nagy; Peter M Lansdorp
Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein.
Cell 2004;117(7):873-86.
2004: Robert A Nordal; Andras Nagy; Melania Pintilie; shun wong
Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3342-53.
2004: Richard Martin; Rachid Lahlil; Annette Damert; Lucile Miquerol; Andras Nagy; Gordon Keller; Trang Hoang
SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis.
Development (Cambridge, England) 2004;131(3):693-702.
2004: Jody J Haigh; Masatsugu Ema; Katharina Haigh; Marina Gertsenstein; Peter Greer; Janet Rossant; Andras Nagy; Erwin F Wagner
Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells.
Blood 2004;103(3):912-20.
2003: Sowmya Viswanathan; Tania Benatar; Maria Mileikovsky; Douglas A Lauffenburger; Andras Nagy; Peter W Zandstra
Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis.
Biotechnology and bioengineering 2003;84(5):505-17.
2003: Li-Juan Duan; Andras Nagy; Guo-Hua Fong
Gastrulation and angiogenesis, not endothelial specification, is sensitive to partial deficiency in vascular endothelial growth factor-a in mice.
Biology of reproduction 2003;69(6):1852-8.
2003: Jody J Haigh; Paula I Morelli; Holger Gerhardt; Katharina Haigh; John Tsien; Annette Damert; Lucile Miquerol; Ulrich Muhlner; Rudiger Klein; Napoleone Ferrara; Erwin F Wagner; Christer Betsholtz; Andras Nagy
Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling.
Developmental biology 2003;262(2):225-41.
2003: András K Fülöp; Anna Földes; Edit Buzás; Krisztina Hegyi; Ildikó H Miklós; László Romics; Mónika Kleiber; Andras Nagy; András Falus; Krisztina Kovács
Hyperleptinemia, visceral adiposity, and decreased glucose tolerance in mice with a targeted disruption of the histidine decarboxylase gene.
Endocrinology 2003;144(10):4306-14.
2003: Alicia Viloria-Petit; Lucile Miquerol; Joanne L Yu; Marina Gertsenstein; Capucine Sheehan; Linda May; Jack Henkin; Corrinne G Lobe; Andras Nagy; Robert S Kerbel; Janusz Rak
Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors.
The EMBO journal 2003;22(16):4091-102.
2003: Martina Metzler; Bo Li; Lu Gan; John Georgiou; Claire-Anne Gutekunst; Yushan Wang; Enrique Torre; Rebecca S Devon; Rosemary Oh; Valerie Legendre-Guillemin; Mark Rich; Christine Alvarez; Marina Gertsenstein; Peter S McPherson; Andras Nagy; Yu Tian Wang; John C Roder; Lynn A Raymond; Michael R Hayden
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.
The EMBO journal 2003;22(13):3254-66.
2003: L A Fitzpatrick; Edit Buzás; T J Gagne; Andras Nagy; Csaba Horváth; Viktória Ferencz; Adám Mester; Béla Kári; M Ruan; András Falus; Julia Barsony
Targeted deletion of histidine decarboxylase gene in mice increases bone formation and protects against ovariectomy-induced bone loss.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6027-32.
2003: Anthony J Apicelli; Erik J Uhlmann; Rebecca L Baldwin; Hao Ding; Andras Nagy; Abhijit Guha; David H Gutmann
Role of the Rap1 GTPase in astrocyte growth regulation.
Glia 2003;42(3):225-34.
2003: Tohru Kimura; Akira Suzuki; Yukiko Fujita; Kentaro Yomogida; Hilda Lomeli; Noriko Asada; Megumi Ikeuchi; Andras Nagy; Tak W Mak; Toru Nakano
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.
Development (Cambridge, England) 2003;130(8):1691-700.
2003: Vera Eremina; Manish Sood; Jody J Haigh; Andras Nagy; Ginette Lajoie; Napoleone Ferrara; Hans-Peter Gerber; Yamato Kikkawa; Jeffrey H Miner; Susan E Quaggin
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases.
The Journal of clinical investigation 2003;111(5):707-16.
2003: Hao Ding; Patrick Shannon; Nelson Lau; Xiaoli Wu; Luba Roncari; Rebecca L Baldwin; Hirohide Takebayashi; Andras Nagy; David H Gutmann; Abhijit Guha
Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.
Cancer research 2003;63(5):1106-13.
2003: Andras Nagy; Norbert Perrimon; Suzanne Sandmeyer; Ronald H Plasterk
Tailoring the genome: the power of genetic approaches.
Nature genetics 2003;33 Suppl():276-84.
2003: Gusztav Belteki; Marina Gertsenstein; David W Ow; Andras Nagy
Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase.
Nature biotechnology 2003;21(3):321-4.
2003: Eva Mezey; Andras Nagy; Ildiko Szalayova; Sharon Key; Andras Bratincsak; Judit Baffi; Tal Shahar
Comment on "Failure of bone marrow cells to transdifferentiate into neural cells in vivo".
Science (New York, N.Y.) 2003;299(5610):1184; author reply 1184.
2003: Nelson Lau; Erik J Uhlmann; Friederike C von Lintig; Andras Nagy; Gerry R Boss; David H Gutmann; Abhijit Guha
Rap1 activity is elevated in malignant astrocytomas independent of tuberous sclerosis complex-2 gene expression.
International journal of oncology 2003;22(1):195-200.
2003: Axel Behrens; Jody Haigh; Fatima Mechta-Grigoriou; Andras Nagy; Moshe Yaniv; Erwin F Wagner
Impaired intervertebral disc formation in the absence of Jun.
Development (Cambridge, England) 2003;130(1):103-9.
2003: Ronald Maatman; Marina Gertsenstein; Emile de Meijer; Andras Nagy; Kristina Vintersten
Aggregation of embryos and embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2003;209():201-30.
2002: Hanna S Radomska; David A Gonzalez; Yutaka Okuno; Hiromi Iwasaki; Andras Nagy; Koichi Akashi; Daniel G Tenen; Claudia S Huettner
Transgenic targeting with regulatory elements of the human CD34 gene.
Blood 2002;100(13):4410-9.
2002: Erna Pap; Károly Rácz; J K Kovács; I Varga; Edit Buzás; B Madarász; C Földes; Csaba Szalai; Takehiko Watanabe; H Ohtsu; A Ichikawa; Andras Nagy; András Falus
Histidine decarboxylase deficiency in gene knockout mice elevates male sex steroid production.
The Journal of endocrinology 2002;175(1):193-9.
2002: Yoshio Hori; Yoshihiro Nihei; Yoshimochi Kurokawa; Atsuo Kuramasu; Yoko Makabe-Kobayashi; Tadashi Terui; Hideyuki Doi; Susumu Satomi; Eiko Sakurai; Andras Nagy; Takehiko Watanabe; Hiroshi Ohtsu
Accelerated clearance of Escherichia coli in experimental peritonitis of histamine-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):1978-83.
2002: J Henri Bayle; Filippo Randazzo; Georg Johnen; Seymour Kaufman; Andras Nagy; Janet Rossant; Gerald R Crabtree
Hyperphenylalaninemia and impaired glucose tolerance in mice lacking the bifunctional DCoH gene.
The Journal of biological chemistry 2002;277(32):28884-91.
2002: Anne-Karina T Perl; Susan E Wert; Andras Nagy; Corrinne G Lobe; Jeffrey A Whitsett
Early restriction of peripheral and proximal cell lineages during formation of the lung.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10482-7.
2002: Yoko Makabe-Kobayashi; Yoshio Hori; Tetsuya Adachi; Satsuki Ishigaki-Suzuki; Yoshihiro Kikuchi; Yutaka Kagaya; Kunio Shirato; Andras Nagy; Azusa Ujike; Toshiyuki Takai; Takehiko Watanabe; Hiroshi Ohtsu
The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis.
The Journal of allergy and clinical immunology 2002;110(2):298-303.
2002: Anna-Katerina Hadjantonakis; Suzanne Macmaster; Andras Nagy
Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal.
BMC biotechnology 2002;2():11.
2002: Hiroshi Ohtsu; Atsuo Kuramasu; Satoshi Tanaka; Tadashi Terui; Noriyasu Hirasawa; Masahiro Hara; Yoko Makabe-Kobayashi; Noboru Yamada; Kazuhiko Yanai; Eiko Sakurai; Mikiko Okada; Kazuo Ohuchi; Atsushi Ichikawa; Andras Nagy; Takehiko Watanabe
Plasma extravasation induced by dietary supplemented histamine in histamine-free mice.
European journal of immunology 2002;32(6):1698-708.
2002: Malcolm Logan; James F Martin; Andras Nagy; Corrinne G Lobe; Eric N Olson; Clifford J Tabin
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer.
Genesis (New York, N.Y. : 2000) 2002;33(2):77-80.
2002: Edmond Y W Chan; Jamal Nasir; Claire-Anne Gutekunst; Sarah Coleman; Alan Maclean; Alex Maas; Martina Metzler; Marina Gertsenstein; Christopher A Ross; Andras Nagy; Michael R Hayden
Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.
Human molecular genetics 2002;11(8):945-59.
2002: Zoltán Wiener; Márton Andrásfalvy; Eva Pállinger; Péter Kovács; Csaba Szalai; Anna Erdei; Sára Tóth; Andras Nagy; András Falus
Bone marrow-derived mast cell differentiation is strongly reduced in histidine decarboxylase knockout, histamine-free mice.
International immunology 2002;14(4):381-7.
2002: Annette Damert; Lucile Miquerol; Marina Gertsenstein; Werner Risau; Andras Nagy
Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation.
Development (Cambridge, England) 2002;129(8):1881-92.
2002: Béla Horváth; András Falus; Sára Tóth; Csaba Szalai; Eszter Lazar-Molnar; Marianna Holub; Edit Buzás; Andras Nagy; Andras K Fulop
Inverse regulation of interleukin-6 (IL-6) and IL-6 receptor in histamine deficient histidine decarboxylase-knock-out mice.
Immunology letters 2002;80(3):151-4.
2002: Hao Ding; Xiaoli Wu; Andras Nagy
Mice with Cre recombinase activatable PDGF-C expression.
Genesis (New York, N.Y. : 2000) 2002;32(2):181-3.
2002: Satoshi Tanaka; Kiyoma Hamada; Noboru Yamada; Yuko Sugita; Shunsuke Tonai; Bèla Hunyady; Miklós Palkovits; András Falus; Takehiko Watanabe; Susumu Okabe; Hiroshi Ohtsu; Atsushi Ichikawa; Andras Nagy
Gastric acid secretion in L-histidine decarboxylase-deficient mice.
Gastroenterology 2002;122(1):145-55.
2002: Marina Gertsenstein; Corrinne G Lobe; Andras Nagy
ES cell-mediated conditional transgenesis.
Methods in molecular biology (Clifton, N.J.) 2002;185():285-307.
2001: SJ Kinder; Tania E Tsang; M Wakamiya; H Sasaki; Richard R Behringer; Andras Nagy; Patrick P L Tam
The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm.
Development (Cambridge, England) 2001;128(18):3623-34.
2001: J Wang; Jesse Mager; Yijing Chen; E Schneider; J C Cross; Andras Nagy; Terry Magnuson
Imprinted X inactivation maintained by a mouse Polycomb group gene.
Nature genetics 2001;28(4):371-5.
2001: Hiroshi Ohtsu; S Tanaka; Tadashi Terui; Yoshio Hori; Yoko Makabe-Kobayashi; Gunnar Pejler; Elena Tchougounova; L Hellman; M Gertsenstein; Noriyasu Hirasawa; Eiko Sakurai; Edit Buzás; Péter Kovács; György Csaba; M Okada; M Hara; L Mar; K Numayama-Tsuruta; Satsuki Ishigaki-Suzuki; Kazuo Ohuchi; A Ichikawa; András Falus; Takehiko Watanabe; Andras Nagy
Mice lacking histidine decarboxylase exhibit abnormal mast cells.
FEBS letters 2001;502(1-2):53-6.
2001: Y Shi; M Zou; E Varkondi; Andras Nagy; László Kozma; Nadir R Farid
Cyclin D1 in thyroid carcinomas.
Thyroid : official journal of the American Thyroid Association 2001;11(7):709-10.
2001: G Csankovszki; Andras Nagy; Rudolf Jaenisch
Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation.
The Journal of cell biology 2001;153(4):773-84.
2001: Krisztina Hegyi; András K Fülöp; Sára Tóth; Edit Buzás; Takehiko Watanabe; H Ohtsu; A Ichikawa; Andras Nagy; András Falus
Histamine deficiency suppresses murine haptoglobin production and modifies hepatic protein tyrosine phosphorylation.
Cellular and molecular life sciences : CMLS 2001;58(5-6):850-4.
2001: Hao Ding; Luba Roncari; Patrick Shannon; Xiaoli Wu; Nelson Lau; J Karaskova; David H Gutmann; J A Squire; Andras Nagy; Abhijit Guha
Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.
Cancer research 2001;61(9):3826-36.
2001: Eva Pállinger; E Búzás; V László; T Watanabe; H Ohtsu; A Ichikawa; Andras Nagy; András Falus
Characterization by flow cytometry of hemopoietic progenitors in bone marrow of histidine decarboxylase knock out and wild type mice.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2001;50 Suppl 2():S89-90.
2001: Zoltán Wiener; E Búzás; Péter Kovács; György Csaba; D Szabó; A Kittel; Eva Pállinger; Takehiko Watanabe; H Ohtsu; A Ichikawa; Andras Nagy; András Falus
Highly reduced peritoneal mast cell number and decreased c-kit expression in histidine decarboxylase knock out mice.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2001;50 Suppl 2():S55-6.
2001: Joanne L Yu; J W Rak; P Carmeliet; Andras Nagy; R S Kerbel; Brenda L Coomber
Heterogeneous vascular dependence of tumor cell populations.
The American journal of pathology 2001;158(4):1325-34.
2001: Emese Pinter; J Haigh; Andras Nagy; Joseph A Madri
Hyperglycemia-induced vasculopathy in the murine conceptus is mediated via reductions of VEGF-A expression and VEGF receptor activation.
The American journal of pathology 2001;158(4):1199-206.
2001: Andras Nagy; László Kozma; István Kiss; István Ember; I Takacs; J Hajdu; Nadir R Farid
Copy number of cancer genes predict tumor grade and survival of pancreatic cancer patients.
Anticancer research 2001;21(2B):1321-5.
2001: Anna-Katerina Hadjantonakis; L L Cox; P P Tam; Andras Nagy
An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant cells of the mouse placenta.
Genesis (New York, N.Y. : 2000) 2001;29(3):133-40.
2001: L Lefebvre; N Dionne; J Karaskova; J A Squire; Andras Nagy
Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity.
Nature genetics 2001;27(3):257-8.
2001: Peter W Zandstra; Andras Nagy
Stem cell bioengineering.
Annual review of biomedical engineering 2001;3():275-305.
2001: Andras Nagy; Janet Rossant
Chimaeras and mosaics for dissecting complex mutant phenotypes.
The International journal of developmental biology 2001;45(3):577-82.
2001: Hao Ding; Luba Roncari; Xiaoli Wu; Nelson Lau; Patrick Shannon; Andras Nagy; Abhijit Guha
Expression and hypoxic regulation of angiopoietins in human astrocytomas.
Neuro-oncology 2001;3(1):1-10.
2001: Andras Nagy; Lynn Mar
Creation and use of a Cre recombinase transgenic database.
Methods in molecular biology (Clifton, N.J.) 2001;158():95-106.
2001: M Tanaka; Anna-Katerina Hadjantonakis; Andras Nagy
Aggregation chimeras. Combining ES cells, diploid and tetraploid embryos.
Methods in molecular biology (Clifton, N.J.) 2001;158():135-54.
2001: Anna-Katerina Hadjantonakis; Andras Nagy
The color of mice: in the light of GFP-variant reporters.
Histochemistry and cell biology 2001;115(1):49-58.
2001: Myriam Hemberger; H Kurz; Annie Orth; Sabine Otto; Angela Lüttges; R Elliott; Andras Nagy; S S Tan; P Tam; Ulrich Zechner; Reinald Fundele
Genetic and developmental analysis of X-inactivation in interspecific hybrid mice suggests a role for the Y chromosome in placental dysplasia.
Genetics 2001;157(1):341-8.
2000: David M Adelman; M Gertsenstein; Andras Nagy; M Celeste Simon; Emin Maltepe
Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses.
Genes & development 2000;14(24):3191-203.
2000: David J Pennisi; Josephine Bowles; Andras Nagy; George E O Muscat; Peter Koopman
Mice null for sox18 are viable and display a mild coat defect.
Molecular and cellular biology 2000;20(24):9331-6.
2000: Hao Ding; Xiaoli Wu; Luba Roncari; Nelson Lau; Patrick Shannon; Andras Nagy; Abhijit Guha
Expression and regulation of neuropilin-1 in human astrocytomas.
International journal of cancer. Journal international du cancer 2000;88(4):584-92.
2000: A Novak; C Guo; W Yang; Andras Nagy; C G Lobe
Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision.
Genesis (New York, N.Y. : 2000) 2000;28(3-4):147-55.
2000: H Ding; X Wu; I Kim; Patrick P L Tam; G Y Koh; Andras Nagy
The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesis.
Mechanisms of development 2000;96(2):209-13.
2000: Lucile Miquerol; B Lowell Langille; Andras Nagy
Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression.
Development (Cambridge, England) 2000;127(18):3941-6.
2000: Anna-Katerina Hadjantonakis; Andras Nagy
FACS for the isolation of individual cells from transgenic mice harboring a fluorescent protein reporter.
Genesis (New York, N.Y. : 2000) 2000;27(3):95-8.
2000: S N Hardouin; Andras Nagy
Mouse models for human disease.
Clinical genetics 2000;57(4):237-44.
2000: N Hardouin; Andras Nagy
Gene-trap-based target site for cre-mediated transgenic insertion.
Genesis (New York, N.Y. : 2000) 2000;26(4):245-52.
2000: Hilda Lomelí; V Ramos-Mejía; Marina Gertsenstein; Corrinne G Lobe; Andras Nagy
Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells.
Genesis (New York, N.Y. : 2000) 2000;26(2):116-7.
2000: Andras Nagy
Cre recombinase: the universal reagent for genome tailoring.
Genesis (New York, N.Y. : 2000) 2000;26(2):99-109.
1999: Jinyi Zhang; Amro Shehabeldin; L A da Cruz; J Butler; AK Somani; Mary K H McGavin; Ivona Kozieradzki; A O dos Santos; Andras Nagy; Sergio Grinstein; Josef M Penninger; Katherine A Siminovitch
Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes.
The Journal of experimental medicine 1999;190(9):1329-42.
1999: SJ Kinder; Tania E Tsang; GA Quinlan; Anna-Katerina Hadjantonakis; Andras Nagy; Patrick P L Tam
The orderly allocation of mesodermal cells to the extraembryonic structures and the anteroposterior axis during gastrulation of the mouse embryo.
Development (Cambridge, England) 1999;126(21):4691-701.
1999: M Tanaka; M Puchyr; Marina Gertsenstein; K Harpal; Rudolf Jaenisch; Janet Rossant; Andras Nagy
Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation.
Mechanisms of development 1999;87(1-2):129-42.
1999: Lucile Miquerol; Marina Gertsenstein; K Harpal; Janet Rossant; Andras Nagy
Multiple developmental roles of VEGF suggested by a LacZ-tagged allele.
Developmental biology 1999;212(2):307-22.
1999: Peter Carmeliet; Yin-Shan Ng; Dieter Nuyens; Gregor Theilmeier; Koen Brusselmans; I Cornelissen; E Ehler; V V Kakkar; Ingeborg Stalmans; Virginie Mattot; J C Perriard; Mieke Dewerchin; Willem Flameng; Andras Nagy; Florea Lupu; Lieve Moons; Désiré Collen; Patricia A D'Amore; David T Shima
Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.
Nature medicine 1999;5(5):495-502.
1999: Corrinne G Lobe; K E Koop; W Kreppner; H Lomeli; Marina Gertsenstein; Andras Nagy
Z/AP, a double reporter for cre-mediated recombination.
Developmental biology 1999;208(2):281-92.
1999: M Nozaki; Kazuhito Ohishi; N Yamada; Taroh Kinoshita; Andras Nagy; Jun Takeda
Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system.
Laboratory investigation; a journal of technical methods and pathology 1999;79(3):293-9.
1999: Anna-Katerina Hadjantonakis; Melinda K Pirity; Andras Nagy
Cre recombinase mediated alterations of the mouse genome using embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 1999;97():101-22.
1999: J Rossant; Andras Nagy
In search of the tabula rasa of human cells.
Nature biotechnology 1999;17(1):23-4.
1998: S Tanaka; Tilo Kunath; Anna-Katerina Hadjantonakis; Andras Nagy; Janet Rossant
Promotion of trophoblast stem cell proliferation by FGF4.
Science (New York, N.Y.) 1998;282(5396):2072-5.
1998: Anna-Katerina Hadjantonakis; Marina Gertsenstein; M Ikawa; M Okabe; Andras Nagy
Generating green fluorescent mice by germline transmission of green fluorescent ES cells.
Mechanisms of development 1998;76(1-2):79-90.
1998: Anna-Katerina Hadjantonakis; Marina Gertsenstein; M Ikawa; M Okabe; Andras Nagy
Non-invasive sexing of preimplantation stage mammalian embryos.
Nature genetics 1998;19(3):220-2.
1998: Andras Nagy; C Moens; E Ivanyi; Judy Pawling; Marina Gertsenstein; Anna-Katerina Hadjantonakis; Melinda K Pirity; Janet Rossant
Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.
Current biology : CB 1998;8(11):661-4.
1998: Janet Rossant; F Guillemot; M Tanaka; K Latham; M Gertenstein; Andras Nagy
Mash2 is expressed in oogenesis and preimplantation development but is not required for blastocyst formation.
Mechanisms of development 1998;73(2):183-91.
1998: C G Lobe; Andras Nagy
Conditional genome alteration in mice.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(3):200-8.
1998: Melinda K Pirity; Anna-Katerina Hadjantonakis; Andras Nagy
Embryonic stem cells, creating transgenic animals.
Methods in cell biology 1998;57():279-93.
1997: M Tanaka; Marina Gertsenstein; Janet Rossant; Andras Nagy
Mash2 acts cell autonomously in mouse spongiotrophoblast development.
Developmental biology 1997;190(1):55-65.
1997: Peter Carmeliet; Lieve Moons; Mieke Dewerchin; Nigel Mackman; T Luther; Georg Breier; V Ploplis; M Müller; Andras Nagy; E Plow; Robert D Gerard; T Edgington; Werner Risau; Désiré Collen
Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system.
Annals of the New York Academy of Sciences 1997;811():191-206.
1997: SA Duncan; Andras Nagy; W Chan
Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos.
Development (Cambridge, England) 1997;124(2):279-87.
1997: László Kozma; István Kiss; Andras Nagy; Szabolcs Szakáll; István Ember
Investigation of c-myc and K-ras amplification in renal clear cell adenocarcinoma.
Cancer letters 1997;111(1-2):127-31.
1996: Peter Carmeliet; Valerie Ferreira; G Breier; Saskia Pollefeyt; L Kieckens; Marina Gertsenstein; M Fahrig; A Vandenhoeck; K Harpal; C Eberhardt; C Declercq; J Pawling; Lieve Moons; Désiré Collen; W Risau; Andras Nagy
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele.
Nature 1996;380(6573):435-9.
1996: Andras Nagy; Janet Rossant
Targeted mutagenesis: analysis of phenotype without germ line transmission.
The Journal of clinical investigation 1996;97(6):1360-5.
1996: Lesley Forrester; Andras Nagy; M Sam; A Watt; L Stevenson; alan bernstein; Alexandra L Joyner; W Wurst
An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1677-82.
1995: Janet Rossant; Andras Nagy
Genome engineering: the new mouse genetics.
Nature medicine 1995;1(6):592-4.
1995: F Guillemot; T Caspary; Shirley M Tilghman; N G Copeland; D J Gilbert; N A Jenkins; D J Anderson; Alexandra L Joyner; Janet Rossant; Andras Nagy
Genomic imprinting of Mash2, a mouse gene required for trophoblast development.
Nature genetics 1995;9(3):235-42.
1994: F Guillemot; Andras Nagy; A Auerbach; Janet Rossant; Alexandra L Joyner
Essential role of Mash-2 in extraembryonic development.
Nature 1994;371(6495):333-6.
1994: C A Chambers; J Kang; J Pawling; B Huber; Nobumichi Hozumi; Andras Nagy
Exogenous Mtv-7 superantigen transgene expression in major histocompatibility complex class II I-E- mice reconstituted with embryonic stem cell-derived hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(3):1138-42.
1993: Andras Nagy; Janet Rossant; R Nagy; W Abramow-Newerly; John C Roder
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8424-8.
1993: Stephen A Wood; N D Allen; J Rossant; A Auerbach; Andras Nagy
Non-injection methods for the production of embryonic stem cell-embryo chimaeras.
Nature 1993;365(6441):87-9.
1993: J Rossant; C Bernelot-Moens; Andras Nagy
Genome manipulation in embryonic stem cells.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;339(1288):207-15.
1991: Lesley Forrester; alan bernstein; Janet Rossant; Andras Nagy
Long-term reconstitution of the mouse hematopoietic system by embryonic stem cell-derived fetal liver.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7514-7.
1990: Andras Nagy; E Gócza; E M Diaz; V R Prideaux; E Iványi; M Markkula; Janet Rossant
Embryonic stem cells alone are able to support fetal development in the mouse.
Development (Cambridge, England) 1990;110(3):815-21.
1989: Andras Nagy; M Sass; M Markkula
Systematic non-uniform distribution of parthenogenetic cells in adult mouse chimaeras.
Development (Cambridge, England) 1989;106(2):321-4.
1989: A Paldi; Andras Nagy; M Markkula; I Barna; L Dezso
Postnatal development of parthenogenetic in equilibrium with fertilized mouse aggregation chimeras.
Development (Cambridge, England) 1989;105(1):115-8.
1987: Andras Nagy; A Páldi; L Dezso; L Varga; Attila Magyar
Prenatal fate of parthenogenetic cells in mouse aggregation chimaeras.
Development (Cambridge, England) 1987;101(1):67-71.