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Gérard Lefranc

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Publications

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Denden S; Braham W; Amri F; Lakhdar R; Lefranc G; Knani J; Ben Chibani J; Haj Khelil A
[Biochemical and molecular diagnosis of alpha 1 antitrypsin deficiency in a Tunisian family]
Lefranc Marie-Paule; Giudicelli Véronique; Ginestoux Chantal; Jabado-Michaloud Joumana; Folch Géraldine; Bellahcene Fatena; Wu Yan; Gemrot Elodie; Brochet Xavier; Lane Jérôme; Regnier Laetitia; Ehrenmann François; Lefranc Gérard; Duroux Patrice
IMGT, the international ImMunoGeneTics information system.
Jiao Hong; Tóth Beáta; Erdos Melinda; Fransson Ingegerd; Rákóczi Eva; Balogh István; Magyarics Zoltán; Dérfalvi Beáta; Csorba Gabriella; Szaflarska Anna; Megarbane Andre; Akatcherian Carlo; Dbaibo Ghassan; Rajnavölgyi Eva; Hammarström Lennart; Kere Juha; Lefranc Gérard; Maródi László
Novel and recurrent STAT3 mutations in hyper-IgE syndrome patients from different ethnic groups.

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All Publications

2009: Denden S; Braham W; Amri F; Lakhdar R; Lefranc G; Knani J; Ben Chibani J; Haj Khelil A
[Biochemical and molecular diagnosis of alpha 1 antitrypsin deficiency in a Tunisian family]
Annales de biologie clinique 2009;67(4):441-5.
2009: Lefranc Marie-Paule; Giudicelli Véronique; Ginestoux Chantal; Jabado-Michaloud Joumana; Folch Géraldine; Bellahcene Fatena; Wu Yan; Gemrot Elodie; Brochet Xavier; Lane Jérôme; Regnier Laetitia; Ehrenmann François; Lefranc Gérard; Duroux Patrice
IMGT, the international ImMunoGeneTics information system.
Nucleic acids research 2009;37(Database issue):D1006-12.
2008: Jiao Hong; Tóth Beáta; Erdos Melinda; Fransson Ingegerd; Rákóczi Eva; Balogh István; Magyarics Zoltán; Dérfalvi Beáta; Csorba Gabriella; Szaflarska Anna; Megarbane Andre; Akatcherian Carlo; Dbaibo Ghassan; Rajnavölgyi Eva; Hammarström Lennart; Kere Juha; Lefranc Gérard; Maródi László
Novel and recurrent STAT3 mutations in hyper-IgE syndrome patients from different ethnic groups.
Molecular immunology 2008;46(1):202-6.
2008: Haj-Khelil A; Denden S; Hlioui L; Hattab N; Daimi H; Leban N; Perrin P; Lefranc G; Ben Chibani J
[Alpha 1 antitrypsin polymorphism associated to asthma and emphysema in a central Tunisian population]
Annales de biologie clinique 2008;66(4):379-84.
2008: Berniell-Lee Gemma; Plaza Stéphanie; Bosch Elena; Calafell Francesc; Jourdan Eric; Césari Maya; Lefranc Gérard; Comas David
Admixture and sexual bias in the population settlement of La Réunion Island (Indian Ocean).
American journal of physical anthropology 2008;136(1):100-7.
2008: Benayoun Béatrice; Baghdiguian Stephen; Lajmanovich Alicia; Bartoli Marc; Daniele Nathalie; Gicquel Evelyne; Bourg Nathalie; Raynaud Fabrice; Pasquier Marie-Anne; Suel Laurence; Lochmuller Hanns; Lefranc Gérard; Richard Isabelle
NF-kappaB-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3, the protein involved in limb-girdle muscular dystrophy type 2A.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1521-9.
2008: Denden S; Haj Khelil A; Perrin P; Daimi H; Leban N; Ouaja A; Mahdouani K; Hlioui L; Lefranc G; Ben Chibani J
Alpha 1 antitrypsin polymorphism in the Tunisian population with special reference to pulmonary disease.
Pathologie-biologie 2008;56(3):106-10.
2007: Alroy Joseph; Pfannl Rolf; Ucci Angelo; Lefranc Gérard; Frattini Annalisa; Mégarbané André
Electron microscopic findings in skin biopsies from patients with infantile osteopetrosis and neuronal storage disease.
Ultrastructural pathology 2007;31(5):333-8.
2007: Leban N; Haj Khelil A; Daimi H; Denden S; Slimene F; Mehdouani K; Abdennaji Guenounou B; Lefranc G; Perrin P; Ben Chibani J
[C3 complement polymorphism in patients suffering from obstructive chronic bronchopneumopathy in Tunisia]
Annales de biologie clinique 2007;65(3):251-6.
2007: Souraty Noëlle; Noun Peter; Djambas-Khayat Claudia; Chouery Eliane; Pangrazio Alessandra; Villa Anna; Lefranc Gérard; Frattini Annalisa; Mégarbané André
Molecular study of six families originating from the Middle-East and presenting with autosomal recessive osteopetrosis.
European journal of medical genetics 2007;50(3):188-99.
2006: Pangrazio Alessandra; Poliani Pietro Luigi; Megarbane André; Lefranc Gérard; Lanino Edoardo; Di Rocco Maja; Rucci Francesca; Lucchini Franco; Ravanini Maria; Facchetti Fabio; Abinun Mario; Vezzoni Paolo; Villa Anna; Frattini Annalisa
Mutations in OSTM1 (grey lethal) define a particularly severe form of autosomal recessive osteopetrosis with neural involvement.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(7):1098-105.
2006: Buhler S; Megarbane A; Lefranc G; Tiercy J-M; Sanchez-Mazas A
HLA-C molecular characterization of a Lebanese population and genetic structure of 39 populations from Europe to India-Pakistan.
Tissue antigens 2006;68(1):44-57.
2006: Capelli C; Redhead N; Romano V; Calì F; Lefranc G; Delague V; Megarbane A; Felice A E; Pascali V L; Neophytou P I; Poulli Z; Novelletto A; Malaspina P; Terrenato L; Berebbi A; Fellous M; Thomas M G; Goldstein D B
Population structure in the Mediterranean basin: a Y chromosome perspective.
Annals of human genetics 2006;70(Pt 2):207-25.
2005: Medlej-Hashim Myrna; Serre Jean-Louis; Corbani Sandra; Saab Odile; Jalkh Nadine; Delague Valérie; Chouery Eliane; Salem Nabiha; Loiselet Jacques; Lefranc Gérard; Mégarbané André
Familial Mediterranean fever (FMF) in Lebanon and Jordan: a population genetics study and report of three novel mutations.
European journal of medical genetics 2005;48(4):412-20.
2005: Lefranc Marie-Paule; Giudicelli Véronique; Kaas Quentin; Duprat Elodie; Jabado-Michaloud Joumana; Scaviner Dominique; Ginestoux Chantal; Clément Oliver; Chaume Denys; Lefranc Gérard
IMGT, the international ImMunoGeneTics information system.
Nucleic acids research 2005;33(Database issue):D593-7.
2005: Lefranc Marie-Paule; Clement Oliver; Kaas Quentin; Duprat Elodie; Chastellan Patrick; Coelho Isabelle; Combres Kora; Ginestoux Chantal; Giudicelli Veronique; Chaume Denys; Lefranc Gerard
IMGT-Choreography for immunogenetics and immunoinformatics.
In silico biology 2005;5(1):45-60.
2005: Lefranc Marie-Paule; Duprat Elodie; Kaas Quentin; Tranne Madeleine; Thiriot Aude; Lefranc Gérard
IMGT unique numbering for MHC groove G-DOMAIN and MHC superfamily (MhcSF) G-LIKE-DOMAIN.
Developmental and comparative immunology 2005;29(11):917-38.
2005: Lefranc Marie-Paule; Pommié Christelle; Kaas Quentin; Duprat Elodie; Bosc Nathalie; Guiraudou Delphine; Jean Christelle; Ruiz Manuel; Da Piédade Isabelle; Rouard Mathieu; Foulquier Elodie; Thouvenin Valérie; Lefranc Gérard
IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains.
Developmental and comparative immunology 2005;29(3):185-203.
2004: Medlej-Hashim Myrna; Loiselet Jacques; Lefranc Gérard; Mégarbané André
[Familial Mediterranean Fever (FMF): from diagnosis to treatment]
Santé (Montrouge, France) 2004;14(4):261-6.
2004: Medlej-Hashim Myrna; Delague Valérie; Chouery Eliane; Salem Nabiha; Rawashdeh Mohammed; Lefranc Gérard; Loiselet Jacques; Mégarbané André
Amyloidosis in familial Mediterranean fever patients: correlation with MEFV genotype and SAA1 and MICA polymorphisms effects.
BMC medical genetics 2004;5():4.
2004: Pommié Christelle; Levadoux Séverine; Sabatier Robert; Lefranc Gérard; Lefranc Marie-Paule
IMGT standardized criteria for statistical analysis of immunoglobulin V-REGION amino acid properties.
Journal of molecular recognition : JMR 2004;17(1):17-32.
2004: Mégarbané Hala; Zablit Cynthia; Waked Naji; Lefranc Gérard; Tomb Roland; Mégarbané André
Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome: report of a new family with additional features and review.
American journal of medical genetics. Part A 2004;124A(3):323-7.
2004: Lefranc Marie-Paule; Giudicelli Véronique; Ginestoux Chantal; Bosc Nathalie; Folch Géraldine; Guiraudou Delphine; Jabado-Michaloud Joumana; Magris Séverine; Scaviner Dominique; Thouvenin Valérie; Combres Kora; Girod David; Jeanjean Stéphanie; Protat Céline; Yousfi-Monod Mehdi; Duprat Elodie; Kaas Quentin; Pommié Christelle; Chaume Denys; Lefranc Gérard
IMGT-ONTOLOGY for immunogenetics and immunoinformatics.
In silico biology 2004;4(1):17-29.
2003: Plaza S; Calafell F; Helal A; Bouzerna N; Lefranc G; Bertranpetit J; Comas D
Joining the pillars of Hercules: mtDNA sequences show multidirectional gene flow in the western Mediterranean.
Annals of human genetics 2003;67(Pt 4):312-28.
2003: Haddad M; Lefranc G; Aftimos G
Local application of IGF1 on dental pulp mechanically exposed; in vivo study on rabbit.
Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie 2003;45(1):12-7.
2003: Lefranc Marie-Paule; Pommié Christelle; Ruiz Manuel; Giudicelli Véronique; Foulquier Elodie; Truong Lisa; Thouvenin-Contet Valérie; Lefranc Gérard
IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains.
Developmental and comparative immunology 2003;27(1):55-77.
2002: Verrelli Brian C; McDonald John H; Argyropoulos George; Destro-Bisol Giovanni; Froment Alain; Drousiotou Anthi; Lefranc Gerard; Helal Ahmed N; Loiselet Jacques; Tishkoff Sarah A
Evidence for balancing selection from nucleotide sequence analyses of human G6PD.
American journal of human genetics 2002;71(5):1112-28.
2002: de la Salle H; Saulquin X; Mansour I; Klayme S; Fricker D; Zimmer J; Cazenave J-P; Hanau D; Bonneville M; Houssaint E; Lefranc G; Naman R
Asymptomatic deficiency in the peptide transporter associated to antigen processing (TAP).
Clinical and experimental immunology 2002;128(3):525-31.
2002: Medlej-Hashim M; Salem N; Chouery E; Rawashdeh M; Delague V; Haffar M; Mansour I; Naman R; Lefranc G; Loiselet J; Mégarbané A
Familial Mediterranean fever: the potential for misdiagnosis of E148V using the E148Q usual RFLP detection method.
Clinical genetics 2002;61(1):71-3.
2001: Medlej-Hashim M; Petit I; Adib S; Chouery E; Salem N; Delague V; Rawashdeh M; Mansour I; Lefranc G; Naman R; Loiselet J; Lecron J C; Serre J L; Mégarbané A
Familial Mediterranean Fever: association of elevated IgD plasma levels with specific MEFV mutations.
European journal of human genetics : EJHG 2001;9(11):849-54.
2001: Sanchez-Mazas A; Bütler-Brunner E; Bütler R; Calderón R; Chaventré A; Dugoujon J M; Hammond M; Lefranc G; Matsumoto H; Osipova L; Politis C; Pullmann R; Langaney A
A worldwide analysis of AG molecular diversity inferred from serology.
Human biology; an international record of research 2001;73(5):637-59.
2001: Tishkoff S A; Varkonyi R; Cahinhinan N; Abbes S; Argyropoulos G; Destro-Bisol G; Drousiotou A; Dangerfield B; Lefranc G; Loiselet J; Piro A; Stoneking M; Tagarelli A; Tagarelli G; Touma E H; Williams S M; Clark A G
Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance.
Science (New York, N.Y.) 2001;293(5529):455-62.
2001: Baghdiguian S; Richard I; Martin M; Coopman P; Beckmann J S; Mangeat P; Lefranc G
Pathophysiology of limb girdle muscular dystrophy type 2A: hypothesis and new insights into the IkappaBalpha/NF-kappaB survival pathway in skeletal muscle.
Journal of molecular medicine (Berlin, Germany) 2001;79(5-6):254-61.
2001: Mansour I; Delague V; Cazeneuve C; Dodé C; Chouery E; Pêcheux C; Medlej-Hashim M; Salem N; El Zein L; Levan-Petit I; Lefranc G; Goossens M; Delpech M; Amselem S; Loiselet J; Grateau G; Mégarbane A; Naman R
Familial Mediterranean fever in Lebanon: mutation spectrum, evidence for cases in Maronites, Greek orthodoxes, Greek catholics, Syriacs and Chiites and for an association between amyloidosis and M694V and M694I mutations.
European journal of human genetics : EJHG 2001;9(1):51-5.
2000: Richard I; Roudaut C; Marchand S; Baghdiguian S; Herasse M; Stockholm D; Ono Y; Suel L; Bourg N; Sorimachi H; Lefranc G; Fardeau M; Sébille A; Beckmann J S
Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IkappaBalpha/nuclear factor kappaB pathway perturbation in mice.
The Journal of cell biology 2000;151(7):1583-90.
2000: Comas D; Calafell F; Benchemsi N; Helal A; Lefranc G; Stoneking M; Batzer M A; Bertranpetit J; Sajantila A
Alu insertion polymorphisms in NW Africa and the Iberian Peninsula: evidence for a strong genetic boundary through the Gibraltar Straits.
Human genetics 2000;107(4):312-9.
2000: Medlej-Hashim M; Rawashdeh M; Chouery E; Mansour I; Delague V; Lefranc G; Naman R; Loiselet J; Mégarbané A
Genetic screening of fourteen mutations in Jordanian familial Mediterranean fever patients.
Human mutation 2000;15(4):384.
2000: Ruiz M; Giudicelli V; Ginestoux C; Stoehr P; Robinson J; Bodmer J; Marsh S G; Bontrop R; Lemaitre M; Lefranc G; Chaume D; Lefranc M P
IMGT, the international ImMunoGeneTics database.
Nucleic acids research 2000;28(1):219-21.
1999: Osipova L P; Posukh O L; Wiebe V P; Miyazaki T; Matsumoto H; Lefranc G; Lefranc M P
BamHI-SacI RFLP and Gm analysis of the immunoglobulin IGHG genes in the Northern Selkups (west Siberia): new haplotypes with deletion, duplication and triplication.
Human genetics 1999;105(6):530-41.
1999: Baghdiguian S; Martin M; Richard I; Pons F; Astier C; Bourg N; Hay R T; Chemaly R; Halaby G; Loiselet J; Anderson L V; Lopez de Munain A; Fardeau M; Mangeat P; Beckmann J S; Lefranc G
Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkappaB alpha/NF-kappaB pathway in limb-girdle muscular dystrophy type 2A.
Nature medicine 1999;5(5):503-11.
1998: Jabara H H; Buckley R H; Roberts J L; Lefranc G; Loiselet J; Khalil G; Geha R S
Role of JAK3 in CD40-mediated signaling.
Blood 1998;92(7):2435-40.
1998: Bozzi F; Lefranc G; Villa A; Badolato R; Schumacher R F; Khalil G; Loiselet J; Bresciani S; O'Shea J J; Vezzoni P; Notarangelo L D; Candotti F
Molecular and biochemical characterization of JAK3 deficiency in a patient with severe combined immunodeficiency over 20 years after bone marrow transplantation: implications for treatment.
British journal of haematology 1998;102(5):1363-6.
1998: Posukh O L; Osipova L P; Kashinskaia Iu O; Ivakin E A; Kriukov Iu A; Karafet T M; Kazakovtseva M A; Skobel'tsina L M; Crawford M G; Lefranc M-P; Lefranc G
[Genetic analysis of the South Altaian population of the Mendur-Sokkon village, Altai Republic]
Genetika 1998;34(1):106-13.
1997: Richard I; Brenguier L; Dinçer P; Roudaut C; Bady B; Burgunder J M; Chemaly R; Garcia C A; Halaby G; Jackson C E; Kurnit D M; Lefranc G; Legum C; Loiselet J; Merlini L; Nivelon-Chevallier A; Ollagnon-Roman E; Restagno G; Topaloglu H; Beckmann J S
Multiple independent molecular etiology for limb-girdle muscular dystrophy type 2A patients from various geographical origins.
American journal of human genetics 1997;60(5):1128-38.
1997: Dard P; Huck S; Frippiat J P; Lefranc G; Langaney A; Lefranc M P; Sanchez-Mazas A
The IGHG3 gene shows a structural polymorphism characterized by different hinge lengths: sequence of a new 2-exon hinge gene.
Human genetics 1997;99(1):138-41.
1996: Beckmann J S; Richard I; Broux O; Fougerousse F; Allamand V; Chiannilkulchai N; Lim L E; Duclos F; Bourg N; Brenguier L; Pasturaud P; Quétier F; Roudaut C; Sunada Y; Meyer J; Dinçer P; Lefranc G; Merlini L; Topaloglu H; Tomé F M; Cohen D; Jackson C E; Campbell K P; Fardeau M
Identification of muscle-specific calpain and beta-sarcoglycan genes in progressive autosomal recessive muscular dystrophies.
Neuromuscular disorders : NMD 1996;6(6):455-62.
1996: Engström P E; Norhagen G; Osipova L; Helal A; Wiebe V; Brusco A; Carbonara A O; Lefranc G; Lefranc M P
Salivary IgG subclasses in individuals with and without homozygous IGHG gene deletions.
Immunology 1996;89(2):178-82.
1996: Dard P; Sanchez-Mazas A; Dugoujon J M; De Lange G; Langaney A; Lefranc M P; Lefranc G
DNA analysis of the immunoglobulin IGHG loci in a Mandenka population from eastern Senegal: correlation with Gm haplotypes and hypotheses for the evolution of the Ig CH region.
Human genetics 1996;98(1):36-47.
1995: Zhang X M; Huck S; Dariavach P; Spilliaert R; Arnason A; Soua Z; Lefranc G; Lefranc M P
Isolation of T cell receptor gamma/delta chain constant genes from minke whale.
Experimental and clinical immunogenetics 1995;12(4):245-52.
1995: Soua Z; Khelif A; Ennabli S; Jemmali M; Taib J; Lefranc G; Lefranc M P
First study of immunoglobulin and T cell receptor gene rearrangements in chronic and acute lymphoblastic leukemias from Tunisia.
Experimental and clinical immunogenetics 1995;12(1):16-30.
1994: Wiebe V; Helal A; Lefranc M P; Lefranc G
Molecular analysis of the T17 immunoglobulin CH multigene deletion (del A1-GP-G2-G4-E).
Human genetics 1994;93(5):520-8.
1993: Chuchana P; Frippiat J P; Blancher A; Lefranc G; Lefranc M P
Haplotypes of the human immunoglobulin lambda IGLV7S1 and IGLV1S1 genes defined by restriction-site polymorphism and insertion/deletion of a 6-kb DNA fragment.
American journal of human genetics 1993;53(2):518-25.
1992: Weill M; Zhang X M; Bernard F; Lefranc G; Lefranc M P
A rare genetic variant of the T cell receptor gamma joining segment TRGJI.
Human genetics 1992;88(3):355.
1992: Lefranc M P; Lefranc G
The constant region genes of the immunoglobulin heavy chains.
Advances in nephrology from the Necker Hospital 1992;21():3-12.
1991: Lenormand B; Ghanem N; Tilly H; Boussemart C; Monconduit M; Piguet H; Lefranc G; Lefranc M P
Rearrangements of immunoglobulin light and heavy chain genes and correlation with phenotypic markers in B-cell chronic lymphocytic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(11):928-36.
1991: Alexandre D; Chuchana P; Roncarolo M G; Yssel H; Spits H; Lefranc G; Lefranc M P
Reciprocal hybrid joints demonstrate successive V-J rearrangements on the same chromosome in the human TCR gamma locus.
International immunology 1991;3(10):973-82.
1991: Chuchana P; Alexandre D; Lefranc G; Lefranc M P
The IGLVA gene as a STS in the human immunoglobulin lambda light chain variable gene locus (located at 22q11)
Nucleic acids research 1991;19(17):4786.
1991: Bensmana M; Bernard F; Zhang X M; Chuchana P; Lefranc M P; Lefranc G
RFLP detected by the transmembrane exon probe of the human immunoglobulin IGHA genes.
Nucleic acids research 1991;19(18):5098.
1991: Hassan M S; Abedi-Valugerdi M; Lefranc G; Hammarström L; Smith C I
Biological half-life of normal and truncated human IgG3 in scid mice.
European journal of immunology 1991;21(5):1319-22.
1991: Bernard F; Ducret F; Buresi C; Lefranc G; Lefranc M P
HindIII/EcoRI RFLP of the human immunoglobulin IGHE gene detected with a C epsilon probe in the French and Tunisian populations.
Human genetics 1991;87(1):101.
1991: Ghanem N; Soua Z; Zhang X G; Zijun M; Zhiwei Y; Lefranc G; Lefranc M P
Polymorphism of the T-cell receptor gamma variable and constant region genes in a Chinese population.
Human genetics 1991;86(5):450-6.
1991: Chuchana P; Bernard F; Lefranc G; Lefranc M P
An STS in the human T-cell receptor delta locus located at 14q11.
Nucleic acids research 1991;19(2):410.
1991: Lefranc M P; Hammarström L; Smith C I; Lefranc G
Gene deletions in the human immunoglobulin heavy chain constant region locus: molecular and immunological analysis.
Immunodeficiency reviews 1991;2(4):265-81.
1991: Bensmana M; Chuchana P; Lefranc G; Lefranc M P
Sequence of the CH1 and hinge-CH2 exons of the human immunoglobulin IGHA2 A2m(2) allele: comparison with the nonallelic and allelic IGHA genes.
Cytogenetics and cell genetics 1991;56(2):128.
1991: Ben Salem M; Ghanem N; Kneissi T; Abbal M; Dugoujon J M; Ben Chibani J; Ellouze F; Lefranc G
[Immunogenetic markers (BF, C2, C4, 21-OH, TNF alpha, TCR beta, Ig) and insulin-dependent diabetes in the Tunisian population: serological and molecular study]
Annales de biologie clinique 1991;49(7):389-96.
1990: Frippiat J P; Chuchana P; Bernard F; Buluwela L; Lefranc G; Lefranc M P
First genomic sequence of a human Ig variable lambda gene belonging to subgroup III.
Nucleic acids research 1990;18(23):7134.
1990: Ghanem N; Lobaccaro J M; Buresi C; Abbal M; Halaby G; Sultan C; Lefranc G
Defective, deleted or converted CYP21B gene and negative association with a rare restriction fragment length polymorphism allele of the factor B gene in congenital adrenal hyperplasia.
Human genetics 1990;86(2):117-25.
1990: Alexandre D; Bernard F; Buresi C; Lefranc G; Lefranc M P
A SacI RFLP of the human T-cell receptor delta (TCRD) joining segment J2.
Nucleic acids research 1990;18(23):7195.
1990: Bernard F; Chuchana P; Lefranc G; Lefranc M P
An STS in the human T cell receptor gamma locus (located at 7p14-15).
Nucleic acids research 1990;18(20):6170.
1990: Chuchana P; Blancher A; Lefranc G; Lefranc M P
HindIII RFLP of the human immunoglobulin V lambda III subgroup genes.
Nucleic acids research 1990;18(20):6179.
1990: Blancher A; Chuchana P; Lefranc G; Lefranc M P
HindIII restriction fragment alleles of the human immunoglobulin V lambda II subgroup genes.
Nucleic acids research 1990;18(20):6178.
1990: Keyeux G; Gilgenkrantz S; Lefranc G; Lefranc M P
Distal trisomy 14q. II. Molecular study of the 14q32 locus in two cases of chromosome 14 rearrangements with partial duplication.
Human genetics 1990;85(6):617-22.
1990: Lefranc G; Lefranc M P
Antibody engineering and perspectives in therapy.
Biochimie 1990;72(9):639-51.
1990: Engström P E; Norhagen G; Bottaro A; Carbonara A O; Lefranc G; Steinitz M; Söder P O; Smith C I; Hammarström L
Subclass distribution of antigen-specific IgA antibodies in normal donors and individuals with homozygous C alpha 1 or C alpha 2 gene deletions.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(1):109-16.
1990: Chuchana P; Blancher A; Brockly F; Alexandre D; Lefranc G; Lefranc M P
Definition of the human immunoglobulin variable lambda (IGLV) gene subgroups.
European journal of immunology 1990;20(6):1317-25.
1990: Lefranc G; Lefranc M P
Regulation of the immunoglobulin gene transcription.
Biochimie 1990;72(1):7-17.
1990: Lobaccaro J M; Ghanem N; Lefranc G; Sultan C
CYP21B gene conversion and complete CYP21A gene deletion in congenital adrenal hyperplasia.
Annales de génétique 1990;33(2):70-5.
1990: Keyeux G; Lefranc M P; Chevailler A; Lefranc G
Molecular analysis of the IGHA and MHC class III region genes in one family with IgA and C4 deficiencies.
Experimental and clinical immunogenetics 1990;7(3):170-80.
1990: Hammarström L; Ghanem N; Smith C I; Lefranc G; Lefranc M P
RFLP of human immunoglobulin genes.
Experimental and clinical immunogenetics 1990;7(1):7-19.
1990: Lobaccaro J M; Ghanem N; Lefranc G; Sultan C
[Molecular genetics of 21-hydroxylase deficiency in congenital adrenal hyperplasia]
Comptes rendus des séances de la Société de biologie et de ses filiales 1990;184(1):75-86.
1989: Keyeux G; Lefranc G; Lefranc M P
A multigene deletion in the human IGH constant region locus involves highly homologous hot spots of recombination.
Genomics 1989;5(3):431-41.
1989: Ghanem N; Bensmana M; Dugoujon J M; Constans J; Lefranc M P; Lefranc G
BamHI and SacI RFLPs of the human immunoglobulin IGHG genes with reference to the Gm polymorphism in African people. Evidence for a major polymorphism.
Human genetics 1989;83(1):37-44.
1989: Keyeux G; Gilgenkrantz S; Lefranc G; Lefranc M P
Molecular characterization of a ring chromosome 14 showing that the PI locus is centromeric to the D14S1 and IGH loci.
Human genetics 1989;82(3):219-22.
1989: Lefranc M P; Chuchana P; Dariavach P; Nguyen C; Huck S; Brockly F; Jordan B; Lefranc G
Molecular mapping of the human T cell receptor gamma (TRG) genes and linkage of the variable and constant regions.
European journal of immunology 1989;19(6):989-94.
1989: Soua Z; Ghanem N; Ben Salem M; Lefranc G; Lefranc M P
Frequencies of the human immunoglobulin IGHA2*M1 and IGHA2*M2 alleles corresponding to the A2m(1) and A2m(2) allotypes in the French, Lebanese, Tunisian and black African populations.
Nucleic acids research 1989;17(9):3625.
1989: Keyeux G; Lefranc G; Lefranc M P
A specific switch alpha probe of the human immunoglobulin IGHA locus.
Nucleic acids research 1989;17(9):3624.
1989: Keyeux G; Ghanem N; Lefranc G; Lefranc M P
Identification of the PvuII RFLPs from the switch human immunoglobulin alpha (IGSA) regions.
Nucleic acids research 1989;17(9):3623.
1989: Chuchana P; Soua Z; Brockly F; Zhang X G; Ghanem N; Lefranc G; Lefranc M P
BamH I restriction fragment alleles of the human T-cell receptor delta (TRD) variable region V2.
Nucleic acids research 1989;17(9):3622.
1989: Brockly F; Alexandre D; Chuchana P; Huck S; Lefranc G; Lefranc M P
First nucleotide sequence of a human immunoglobulin variable lambda gene belonging to subgroup II.
Nucleic acids research 1989;17(10):3976.
1989: Alexandre D; Chuchana P; Brockly F; Blancher A; Lefranc G; Lefranc M P
First genomic sequence of a human Ig variable lambda gene belonging to subgroup I. Functional genes, pseudogenes and vestigial sequences are interspersed in the IGLV locus.
Nucleic acids research 1989;17(10):3975.
1989: Chuchana P; Soua Z; Ghanem N; Brockly F; Lefranc G; Lefranc M P
Two KpnI restriction fragment alleles of the human T-cell receptor delta (TRD) joining segment J2.
Nucleic acids research 1989;17(3):1275.
1989: Ghanem N; Chuchana P; Dariavach P; Brockly F; Lefranc G; Lefranc M P
SacI polymorphism defined by human T-cell receptor gamma (TCRG) variable gene V11.
Nucleic acids research 1989;17(3):1271.
1989: Ghanem N; Dariavach P; Lefranc G; Lefranc M P
A TaqI RFLP of the human T-cell receptor gamma (TCRG) variable gene V11.
Nucleic acids research 1989;17(3):1270.
1989: Ghanem N; Buresi C; Lefranc G; Lefranc M P
A unique RFLP in the human T-cell receptor gamma constant region gene TRGC1.
Nucleic acids research 1989;17(1):471.
1989: Hammarström L; Dugoujon J M; de Lange G G; Ghanem N; Lefranc G; Smith C I
No influence of conversions affecting allotype expression on the IgG subclass restriction of specific antibodies.
Experimental and clinical immunogenetics 1989;6(1):60-7.
1989: Ghanem N; Dugoujon J M; Lefranc M P; Lefranc G
BstEII restriction fragment alleles and haplotypes of the human IGHG genes with reference to the BamHI/SacI RFLPs and to the Gm polymorphism.
Experimental and clinical immunogenetics 1989;6(1):39-54.
1989: Ghanem N; Buresi C; Moisan J P; Bensmana M; Chuchana P; Huck S; Lefranc G; Lefranc M P
Deletion, insertion, and restriction site polymorphism of the T-cell receptor gamma variable locus in French, Lebanese, Tunisian, and black African populations.
Immunogenetics 1989;30(5):350-60.
1989: Huck S; Lefranc G; Lefranc M P
A human immunoglobulin IGHG3 allele (Gmb0,b1,c3,c5,u) with an IGHG4 converted region and three hinge exons.
Immunogenetics 1989;30(4):250-7.
1989: Buresi C; Ghanem N; Huck S; Lefranc G; Lefranc M P
Exon duplication and triplication in the human T-cell receptor gamma constant region genes and RFLP in French, Lebanese, Tunisian, and black African populations.
Immunogenetics 1989;29(3):161-72.
1988: Lobaccaro J M; Ghanem N; Sultan C; Lefranc G
A new TaqI polymorphism of the complement factor B gene.
Nucleic acids research 1988;16(24):11851.
1988: Ghanem N; Uring-Lambert B; Abbal M; Hauptmann G; Lefranc M P; Lefranc G
Polymorphism of MHC class III genes: definition of restriction fragment linkage groups and evidence for frequent deletions and duplications.
Human genetics 1988;79(3):209-18.
1988: Ghanem N; Dugoujon J M; Bensmana M; Huck S; Lefranc M P; Lefranc G
Restriction fragment haplotypes in the human immunoglobulin IGHG locus and their correlation with the Gm polymorphism.
European journal of immunology 1988;18(7):1067-72.
1988: Ghanem N; Lefranc M P; Lefranc G
Definition of the RFLP alleles in the human immunoglobulin IGHG gene locus.
European journal of immunology 1988;18(7):1059-65.
1988: Persson M A; Brown S E; Steward M W; Hammarström L; Smith C I; Howard C R; Wahl M; Rynnel-Dagöö B; Lefranc G; Carbonara A O
IgG subclass-associated affinity differences of specific antibodies in humans.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(11):3875-9.
1988: Bensmana M; Huck S; Lefranc G; Lefranc M P
The human immunoglobulin pseudo-gamma IGHGP gene shows no major structural defect.
Nucleic acids research 1988;16(7):3108.
1988: Helal A N; de Lange G; Van Loghem E; Lefranc G
Uncommon Gm* haplotypes in the Tunisian population: further contribution to the genetics of the IgG immunoglobulins.
Experimental and clinical immunogenetics 1988;5(1):24-38.
1988: Helal A N; Rivat-Peran L; Van Loghem E; de Lange G; Langaney A; Lefranc G
Further contribution of common Gm*-Am* haplotypes and Km* alleles in the characterization of the Tunisian population.
Experimental and clinical immunogenetics 1988;5(1):1-14.
1988: Ghanem N; Dariavach P; Bensmana M; Chibani J; Lefranc G; Lefranc M P
Polymorphism of immunoglobulin lambda constant region genes in populations from France, Lebanon and Tunisia.
Experimental and clinical immunogenetics 1988;5(4):186-95.
1987: Dariavach P; Lefranc G; Lefranc M P
Human immunoglobulin C lambda 6 gene encodes the Kern+Oz-lambda chain and C lambda 4 and C lambda 5 are pseudogenes.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):9074-8.
1987: Hammarström L; Carbonara A O; DeMarchi M; Lefranc G; Möller G; Smith C I; Zegers B J
Subclass restriction pattern of antigen-specific antibodies in donors with defective expression of IgG or IgA subclass heavy chain constant region genes.
Clinical immunology and immunopathology 1987;45(3):461-70.
1987: Lefranc M P; Lefranc G
Human immunoglobulin heavy-chain multigene deletions in healthy individuals.
FEBS letters 1987;213(2):231-7.
1987: Hammarström L; Carbonara A O; DeMarchi M; Lefranc G; Lefranc M P; Smith C I
Generation of the antibody repertoire in individuals with multiple immunoglobulin heavy chain constant region gene deletions.
Scandinavian journal of immunology 1987;25(2):189-94.
1987: Ghanem N; Lefranc M P; Lefranc G
Polymorphism of the complement C3 gene in the Lebanese population.
Experimental and clinical immunogenetics 1987;4(4):222-6.
1986: Huck S; Keyeux G; Ghanem N; Lefranc M P; Lefranc G
A gamma 3 hinge region probe: first specific human immunoglobulin subclass probe.
FEBS letters 1986;208(2):221-30.
1986: Huck S; Fort P; Crawford D H; Lefranc M P; Lefranc G
Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes.
Nucleic acids research 1986;14(4):1779-89.
1986: Lefranc M P; Helal A N; de Lange G; Chaabani H; van Loghem E; Lefranc G
Gene conversion in human immunoglobulin gamma locus shown by unusual location of IgG allotypes.
FEBS letters 1986;196(1):96-102.
1986: Hammarström L; Lefranc G; Lefranc M P; Persson M A; Smith C I
Aberrant pattern of anti-carbohydrate antibodies in immunoglobulin class or subclass-deficient donors.
Monographs in allergy 1986;20():50-6.
1985: Chibani J; Lefranc G; Constans J
Serum protein polymorphism among Tunisian Berbers: haptoglobin, transferrin and group-specific component subtypes, C3 and BF types.
Annals of human biology 1985;12(5):449-62.
1984: Davrinche C; Charlionet R; Rivat C; Helal A N; Lefranc G
Inulin-induced activation of factor B in whole serum: description of structural modifications in the Ba fragment.
European journal of immunology 1984;14(10):957-61.
1984: Chaabani H; Helal A N; van Loghem E; Langaney A; Benammar Elgaaied A; Rivat Peran L; Lefranc G
Genetic study of Tunisian Berbers. I. Gm, Am and Km immunoglobulin allotypes and ABO blood groups.
Journal of immunogenetics 1984;11(2):107-13.
1984: Chaabani H; Martin J P; Frants R R; Lefranc G
Genetic study of Tunisian Berbers. II. Alpha 1-antitrypsin (Pi) polymorphism: report of a new allele (Pi S Berber).
Experimental and clinical immunogenetics 1984;1(1):19-24.
1983: Lefranc M P; Lefranc G; de Lange G; Out T A; van den Broek P J; van Nieuwkoop J; Radl J; Helal A N; Chaabani H; van Loghem E
Instability of the human immunoglobulin heavy chain constant region locus indicated by different inherited chromosomal deletions.
Molecular biology & medicine 1983;1(2):207-17.
1983: Helal A N; Lefranc G; Hauptmann G; Goetz J; Tongio M M; Davrinche C; Rivat C; Cavelier B; Chibani J; Chaabani H
HLA A*, B*-BF* and C4 A*, B* allele associations, with special reference to BF*S07, in the Tunisian population.
Journal of immunogenetics 1983;10(3):205-8.
1983: Lefranc G; Chaabani H; Van Loghem E; Lefranc M P; De Lange G; Helal A N
Simultaneous absence of the human IgG1, IgG2, IgG4 and IgA1 subclasses: immunological and immunogenetical considerations.
European journal of immunology 1983;13(3):240-4.
1982: Lefranc M P; Lefranc G; Rabbitts T H
Inherited deletion of immunoglobulin heavy chain constant region genes in normal human individuals.
Nature 1982;300(5894):760-2.
1982: Lefranc G; Lefranc M P; Helal A N; Boukef K; Chaabani H; Gandoura M S; van Loghem E
Unusual heavy chains of human IgG immunoglobulins: rearrangements of the ch domain exons.
Journal of immunogenetics 1982;9(1):1-9.
1982: van Loghem E; de Lange G; van Leeuwen A M; van Eede P H; Nijenhuis L E; Lefranc M P; Lefranc G
Human IgG allotypes co-occurring in more than one IgG subclass.
Vox sanguinis 1982;43(6):301-9.
1981: Lefranc M P; Lefranc G; Farhat M; Jmour R; Boukef K; Beuzard Y; Galacteros F; Rosa J
Frequency of human A gamma 75Thr globin chain in a population from Tunisia.
Human genetics 1981;59(1):89-91.
1981: Lefranc M P; Chibani J; Helal A N; Boukef K; Seger J; Lefranc G
Human transferrin (Tf) and group-specific component (Gc) subtypes in Tunisia.
Human genetics 1981;59(1):60-3.
1981: Lefranc G; Lefranc M P; Seger J; Salier J P; Chakhachiro L; Loiselet J
Sex limited ahaptoglobinaemia.
Human genetics 1981;58(3):294-7.
1981: Davrinche C; Rivat C; Rivat-Peran L; Helal A N; Boukef K; Lefranc M P; Lefranc G
Genetic variants of human C3 and properdin factor B in a population from Tunisia.
Human heredity 1981;31(5):299-303.
1980: van Loghem E; Sukernik R I; Osipova L P; Zegers B J; Matsumoto H; de Lange G; Lefranc G
Gene deletion and gene duplication within the cluster of human heavy-chain genes. Selective absence of IgG sub-classes.
Journal of immunogenetics 1980;7(4):285-99.
1980: Lefranc G; Lefranc M P
Discontinuous genes and DNA sequence transposition: a model for immunoglobulin chain synthesis.
Journal of immunogenetics 1980;7(3):207-14.
1980: Salier J P; Rivat L; Daveau M; Lefranc G; Breton P; de Menibus C H; Henocq A; Fudenberg H H
Quantitative studies of Gm allotypes. V. Simultaneous presence of latent Gm allotypes and deficient Gm genes in a family with hypogammaglobulinaemic probands.
Journal of immunogenetics 1980;7(2):123-35.
1979: Serre J L; Lefranc G; Loiselet J; Jacquard A
HLA markers in six Lebanese religious subpopulations.
Tissue antigens 1979;14(3):251-5.
1979: Lefranc G; Dumitresco S M; Salier J P; Rivat L; de Lange G; van Loghem E; Loiselet J
Familial lack of the IgG3 subclass: gene elimination or turning off expression and neutral evolution in the immune system.
Journal of immunogenetics 1979;6(4):215-21.
1979: Lefranc G; de Lange G; Rivat L; Langaney A; Lefranc M P; Ellouze F; Sfar G; Sfar M; van Loghem E
Gm, Am and Km immunoglobulin allotypes of two populations in Tunisia.
Human genetics 1979;50(2):199-211.
1978: Lefranc G; Rivat L; Serre J L; Lalouel J M; Pison G; Loiselet J; Ropartz C; de Lange G; van Loghem E
Common and uncommon immunoglobulin haplotypes among Lebanese communities.
Human genetics 1978;41(2):197-209.
1977: Lefranc G; Rivat L; Salier J P; van Loghem E; Aydenian H; Zalzal P; Chakhachiro L; Loiselet J; Ropartz C
Recombination, mutation, or constitutive expression at a Gm locus and familial hypergammaglobulinemia.
American journal of human genetics 1977;29(5):523-36.
1976: Geha R S; Malakian A; LeFranc G; Chayban D; Serre J L
Immunologic reconstitution in severe combined immunodeficiency following transplantation with parental bone marrow.
Pediatrics 1976;58(3):451-5.

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