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Germán Camejo

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Chemicals & Drugs

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Arteriosclerosis

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Annika Asplund; Vincent Fridén; Pia Stillemark-Billton; Germán Camejo; Göran Bondjers
Macrophages exposed to hypoxia secrete proteoglycans for which LDL has higher affinity.
Annika Asplund; Pia Stillemark-Billton; Erik Larsson; Ellen Knutsen Rydberg; Jonatan Moses; Lillemor Mattsson Hultén; Björn Fagerberg; Germán Camejo; Göran Bondjers
Hypoxic regulation of secreted proteoglycans in macrophages.
Annika Asplund; Gunnel Ostergren-Lundén; Germán Camejo; Pia Stillemark-Billton; Göran Bondjers
Hypoxia increases macrophage motility, possibly by decreasing the heparan sulfate proteoglycan biosynthesis.

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All Publications

2011: Annika Asplund; Vincent Fridén; Pia Stillemark-Billton; Germán Camejo; Göran Bondjers
Macrophages exposed to hypoxia secrete proteoglycans for which LDL has higher affinity.
Atherosclerosis 2011;215(1):77-81.
2010: Annika Asplund; Pia Stillemark-Billton; Erik Larsson; Ellen Knutsen Rydberg; Jonatan Moses; Lillemor Mattsson Hultén; Björn Fagerberg; Germán Camejo; Göran Bondjers
Hypoxic regulation of secreted proteoglycans in macrophages.
Glycobiology 2010;20(1):33-40.
2009: Annika Asplund; Gunnel Ostergren-Lundén; Germán Camejo; Pia Stillemark-Billton; Göran Bondjers
Hypoxia increases macrophage motility, possibly by decreasing the heparan sulfate proteoglycan biosynthesis.
Journal of leukocyte biology 2009;86(2):381-8.
2008: Marcus Ståhlman; Pia Davidsson; Ida Kanmert; Birgitta Rosengren; Jan Borén; Björn Fagerberg; Germán Camejo
Proteomics and lipids of lipoproteins isolated at low salt concentrations in D2O/sucrose or in KBr.
Journal of lipid research 2008;49(2):481-90.
2007: Mariam Rodriguéz-Lee; Göran Bondjers; Germán Camejo
Fatty acid-induced atherogenic changes in extracellular matrix proteoglycans.
Current opinion in lipidology 2007;18(5):546-53.
2007: Heike Hellmold; Hui Zhang; Ulf Andersson; Bo Blomgren; Tom Holland; Anna-Lena Berg; Marie Elebring; Niclas Sjögren; Krister Bamberg; Björn Dahl; Rolf Westerberg; Birgitta Dillner; Jonathan D Tugwood; Jonathan Tugwood; Ruth Roberts; Erik Lundholm; Germán Camejo; Inger Skånberg; John Evans
Tesaglitazar, a PPARalpha/gamma agonist, induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2007;98(1):63-74.
2007: Kashif Sheikh; Germán Camejo; Boel Lanne; Torbjörn Halvarsson; Marie Rydén Landergren; Nicholas D Oakes
Beyond lipids, pharmacological PPARalpha activation has important effects on amino acid metabolism as studied in the rat.
American journal of physiology. Endocrinology and metabolism 2007;292(4):E1157-65.
2006: Birgitta Rosengren; Ann-Cathrine Jönsson-Rylander; Helena Peilot; Germán Camejo; Eva Hurt-Camejo
Distinctiveness of secretory phospholipase A2 group IIA and V suggesting unique roles in atherosclerosis.
Biochimica et biophysica acta 2006;1761(11):1301-8.
2006: A Susanne M Zadelaar; Lianne S M Boesten; J Wouter Jukema; Bart J M van Vlijmen; Teake Kooistra; Jef J Emeis; Erik Lundholm; Germán Camejo; Louis M Havekes
Dual PPARalpha/gamma agonist tesaglitazar reduces atherosclerosis in insulin-resistant and hypercholesterolemic ApoE*3Leiden mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(11):2560-6.
2006: Mariam Rodríguez-Lee; Gunnel Ostergren-Lundén; Boel Wallin; Jonatan Moses; Göran Bondjers; Germán Camejo
Fatty acids cause alterations of human arterial smooth muscle cell proteoglycans that increase the affinity for low-density lipoprotein.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):130-5.
2005: Nicholas D Oakes; Pia Thalén; Therese Hultstrand; Severina Jacinto; Germán Camejo; Boel Wallin; Bengt Ljung
Tesaglitazar, a dual PPAR{alpha}/{gamma} agonist, ameliorates glucose and lipid intolerance in obese Zucker rats.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(4):R938-46.
2005: Germán Camejo
Differential antiatherogenic effects of PPARalpha versus PPARgamma agonists: should we be surprised?
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):1763-4.
2005: Pia Davidsson; Johannes Hulthe; Björn Fagerberg; Britt-Marie Olsson; Carina Hallberg; Björn Dahllöf; Germán Camejo
A proteomic study of the apolipoproteins in LDL subclasses in patients with the metabolic syndrome and type 2 diabetes.
Journal of lipid research 2005;46(9):1999-2006.
2003: Germán Camejo
Hydrolytic enzymes released from resident macrophages and located in the intima extracellular matrix as agents that modify retained apolipoprotein B lipoproteins.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(8):1312-3.
2003: Linda Svensson; Germán Camejo; ANNA CABRÉ; Joan-Carles Vallvé; J Pedreño; Kristina Norén; Olov Wiklund; Lillemor Mattsson Hultén
Fatty acids modulate the effect of darglitazone on macrophage CD36 expression.
European journal of clinical investigation 2003;33(6):464-71.
2003: Germán Camejo
PPAR agonists in the treatment of insulin resistance and associated arterial disease.
International journal of clinical practice. Supplement 2003;(134):36-44.
2002: Bengt Ljung; Krister Bamberg; Björn Dahllöf; Ann Kjellstedt; Nicholas D Oakes; Jörgen Östling; Lennart Svensson; Germán Camejo
AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats.
Journal of lipid research 2002;43(11):1855-63.
2002: Germán Camejo; Urban Olsson; Eva Hurt-Camejo; Nahid Baharamian; Göran Bondjers
The extracellular matrix on atherogenesis and diabetes-associated vascular disease.
Atherosclerosis. Supplements 2002;3(1):3-9.
2002: Peter Sartipy; Germán Camejo; Lennart Svensson; Eva Hurt-Camejo
Phospholipase A2 modification of lipoproteins: potential effects on atherogenesis.
Advances in experimental medicine and biology 2002;507():3-7.
2002: Nicholas D Oakes; Bengt Ljung; Germán Camejo
Correction of dysfunctional fatty acid metabolism using peroxisome proliferator activated receptor gamma agonists.
Journal of the Royal Society of Medicine 2002;95 Suppl 42():33-8.
2001: Eva Hurt-Camejo; S Paredes; L Masana; Germán Camejo; Peter Sartipy; Birgitta Rosengren; J Pedreno; J C Vallve; P Benito; Olov Wiklund
Elevated levels of small, low-density lipoprotein with high affinity for arterial matrix components in patients with rheumatoid arthritis: possible contribution of phospholipase A2 to this atherogenic profile.
Arthritis and rheumatism 2001;44(12):2761-7.
2001: Urban Olsson; A C Egnell; M R Lee; G O Lundén ; M Lorentzon; M Salmivirta; Göran Bondjers; Germán Camejo
Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance.
Diabetes 2001;50(9):2126-32.
2001: Ana Fernandez; F López; A Tablante; Egidio Romano; Eva Hurt-Camejo; Germán Camejo; Rafael Apitz-Castro
Intravascular hemolysis increases atherogenicity of diet-induced hypercholesterolemia in rabbits in spite of heme oxygenase-1 gene and protein induction.
Atherosclerosis 2001;158(1):103-11.
2001: Eva Hurt-Camejo; Germán Camejo; Helena Peilot; Katariina Öörni; P Kovanen
Phospholipase A(2) in vascular disease.
Circulation research 2001;89(4):298-304.
2001: Germán Camejo; Bengt Ljung; Nicholas D Oakes
Pharmacological treatment of insulin resistance in obesity.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2001;11(4):275-84.
2001: Eva Hurt-Camejo; Germán Camejo
[Why are plasmatic apoB lipoproteins atherogenic? The hypothesis of response to retention].
Investigación clínica 2001;42 Suppl 1():43-73.
2000: Eva Hurt-Camejo; Germán Camejo; Peter Sartipy
Phospholipase A2 and small, dense low-density lipoprotein.
Current opinion in lipidology 2000;11(5):465-71.
1999: Peter Sartipy; Germán Camejo; L Svensson; Eva Hurt-Camejo
Phospholipase A(2) modification of low density lipoproteins forms small high density particles with increased affinity for proteoglycans and glycosaminoglycans.
The Journal of biological chemistry 1999;274(36):25913-20.
1999: Germán Camejo; Eva Hurt-Camejo; U Olsson; Göran Bondjers
Lipid mediators that modulate the extracellular matrix structure and function in vascular cells.
Current atherosclerosis reports 1999;1(2):142-9.
1999: Eva Hurt-Camejo; Birgitta Rosengren; Peter Sartipy; K Elfsberg; Germán Camejo; L Svensson
CD44, a cell surface chondroitin sulfate proteoglycan, mediates binding of interferon-gamma and some of its biological effects on human vascular smooth muscle cells.
The Journal of biological chemistry 1999;274(27):18957-64.
1999: Nicholas D Oakes; A Kjellstedt; G B Forsberg; T Clementz; Germán Camejo; Stuart M Furler; Edward W Kraegen; M Olwegård-Halvarsson; Arthur B Jenkins; Bengt Ljung
Development and initial evaluation of a novel method for assessing tissue-specific plasma free fatty acid utilization in vivo using (R)-2-bromopalmitate tracer.
Journal of lipid research 1999;40(6):1155-69.
1999: Ulf Lundstam; Eva Hurt-Camejo; G Olsson; Peter Sartipy; Germán Camejo; Olov Wiklund
Proteoglycans contribution to association of Lp(a) and LDL with smooth muscle cell extracellular matrix.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1162-7.
1999: Urban Olsson; Göran Bondjers; Germán Camejo
Fatty acids modulate the composition of extracellular matrix in cultured human arterial smooth muscle cells by altering the expression of genes for proteoglycan core proteins.
Diabetes 1999;48(3):616-22.
1998: Germán Camejo; Eva Hurt-Camejo; Olov Wiklund; Göran Bondjers
Association of apo B lipoproteins with arterial proteoglycans: pathological significance and molecular basis.
Atherosclerosis 1998;139(2):205-22.
1998: Germán Camejo; C Halberg; A Manschik-Lundin; Eva Hurt-Camejo; Birgitta Rosengren; H Olsson; G I Hansson; G B Forsberg; B Ylhen
Hemin binding and oxidation of lipoproteins in serum: mechanisms and effect on the interaction of LDL with human macrophages.
Journal of lipid research 1998;39(4):755-66.
1998: Germán Camejo; Boel Wallin; M Enojärvi
Analysis of oxidation and antioxidants using microtiter plates.
Methods in molecular biology (Clifton, N.J.) 1998;108():377-87.
1998: Eva Hurt-Camejo; Germán Camejo; Peter Sartipy
Measurements of proteoglycan-lipoprotein interaction by gel mobility shift assay.
Methods in molecular biology (Clifton, N.J.) 1998;110():267-79.
1997: Eva Hurt-Camejo; Germán Camejo
Potential involvement of type II phospholipase A2 in atherosclerosis.
Atherosclerosis 1997;132(1):1-8.
1997: Eva Hurt-Camejo; Urban Olsson; Olov Wiklund; Göran Bondjers; Germán Camejo
Cellular consequences of the association of apoB lipoproteins with proteoglycans. Potential contribution to atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(6):1011-7.
1997: Urban Olsson; Germán Camejo; Eva Hurt-Camejo; K Elfsber; Olov Wiklund; Göran Bondjers
Possible functional interactions of apolipoprotein B-100 segments that associate with cell proteoglycans and the ApoB/E receptor.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(1):149-55.
1996: Björn Fagerberg; Olov Wiklund; Stefan Agewall; Germán Camejo; R J Wikstrand
Multifactorial treatment of hypertensive men at high cardiovascular risk and low-density lipoprotein cholesterol affinity to human arterial proteoglycans.
European journal of clinical investigation 1996;26(11):960-5.
1996: Peter Sartipy; B Johansen; Germán Camejo; Birgitta Rosengren; Göran Bondjers; Eva Hurt-Camejo
Binding of human phospholipase A2 type II to proteoglycans. Differential effect of glycosaminoglycans on enzyme activity.
The Journal of biological chemistry 1996;271(42):26307-14.
1996: Rafael Carmena; Juan F Ascaso; Germán Camejo; G Varela; Eva Hurt-Camejo; Jose Ordovas; J Martinez-Valls; M Bergstöm; B Wallin
Effect of olive and sunflower oils on low density lipoprotein level, composition, size, oxidation and interaction with arterial proteoglycans.
Atherosclerosis 1996;125(2):243-55.
1996: Olov Wiklund; Göran Bondjers; I Wright; Germán Camejo
Insoluble complex formation between LDL and arterial proteoglycans in relation to serum lipid levels and effects of lipid lowering drugs.
Atherosclerosis 1996;119(1):57-67.
1995: E H Camejo; Birgitta Rosengren; Germán Camejo; Peter Sartipy; Gunnar Fager; Göran Bondjers
Interferon gamma binds to extracellular matrix chondroitin-sulfate proteoglycans, thus enhancing its cellular response.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(9):1456-65.
1995: Gunnar Fager; Germán Camejo; Urban Olsson; Gunnel Ostergren-Lundén; Florentyna Lustig; Göran Bondjers
Binding of platelet-derived growth factor and low density lipoproteins to glycosaminoglycan species produced by human arterial smooth muscle cells.
Journal of cellular physiology 1995;163(2):380-92.
1994: B Wallin; Germán Camejo
Lipoprotein oxidation and measurement of hydroperoxide formation in a single microtitre plate.
Scandinavian journal of clinical and laboratory investigation 1994;54(4):341-6.
1994: C Hallberg; M Hådén; M Bergström; G Hanson; Knut S Pettersson; C Westerlund; Göran Bondjers; A M Ostlund-Lindqvist; Germán Camejo
Lipoprotein fractionation in deuterium oxide gradients: a procedure for evaluation of antioxidant binding and susceptibility to oxidation.
Journal of lipid research 1994;35(1):1-9.
1993: Germán Camejo; Gunnar Fager; Birgitta Rosengren; Eva Hurt-Camejo; Göran Bondjers
Binding of low density lipoproteins by proteoglycans synthesized by proliferating and quiescent human arterial smooth muscle cells.
The Journal of biological chemistry 1993;268(19):14131-7.
1993: Urban Olsson; Germán Camejo; Göran Bondjers
Binding of a synthetic apolipoprotein B-100 peptide and peptide analogues to chondroitin 6-sulfate: effects of the lipid environment.
Biochemistry 1993;32(7):1858-65.
1993: B Wallin; Birgitta Rosengren; H G Shertzer; Germán Camejo
Lipoprotein oxidation and measurement of thiobarbituric acid reacting substances formation in a single microtiter plate: its use for evaluation of antioxidants.
Analytical biochemistry 1993;208(1):10-5.
1992: I Carvajal; I Malavé; C Correa; C Castillo; M Pérez; S Hammar; Germán Camejo
[Changes in the serum lipid fractions of malnourished children with and without clinical infection. Paradoxical hypertriglyceridemia in malnutrition].
Archivos latinoamericanos de nutrición 1992;42(3):250-8.
1992: Eva Hurt-Camejo; Germán Camejo; Birgitta Rosengren; F López; C Ahlström; Gunnar Fager; Göran Bondjers
Effect of arterial proteoglycans and glycosaminoglycans on low density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(5):569-83.
1992: Gunnar Fager; Germán Camejo; Urban Olsson; Gunnel Ostergren-Lundén; Göran Bondjers
Heparin-like glycosaminoglycans influence growth and phenotype of human arterial smooth muscle cells in vitro. II. The platelet-derived growth factor A-chain contains a sequence that specifically binds heparin.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1992;28A(3 Pt 1):176-80.
1992: Gunnar Fager; Germán Camejo; Göran Bondjers
Heparin-like glycosaminoglycans influence growth and phenotype of human arterial smooth muscle cells in vitro. I. Evidence for reversible binding and inactivation of the platelet-derived growth factor by heparin.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1992;28A(3 Pt 1):168-75.
1991: Germán Camejo; Eva Hurt-Camejo; Birgitta Rosengren; Olov Wiklund; F López; Göran Bondjers
Modification of copper-catalyzed oxidation of low density lipoprotein by proteoglycans and glycosaminoglycans.
Journal of lipid research 1991;32(12):1983-91.
1991: Germán Camejo; E Hurt; M Thubrikar; Göran Bondjers
Modification of low density lipoprotein association with the arterial intima. A possible environment for the antiatherogenic action of beta-blockers.
Circulation 1991;84(6 Suppl):VI17-22.
1991: Urban Olsson; Germán Camejo; Sven-Olof Olofsson; Göran Bondjers
Molecular parameters that control the association of low density lipoprotein apo B-100 with chondroitin sulphate.
Biochimica et biophysica acta 1991;1097(1):37-44.
1991: Germán Camejo; E Hurt; Olov Wiklund; Birgitta Rosengren; F López; Göran Bondjers
Modifications of low-density lipoprotein induced by arterial proteoglycans and chondroitin-6-sulfate.
Biochimica et biophysica acta 1991;1096(3):253-61.
1991: Olov Wiklund; L Mattsson; Tom Björnheden; Germán Camejo; Göran Bondjers
Uptake and degradation of low density lipoproteins in atherosclerotic rabbit aorta: role of local LDL modification.
Journal of lipid research 1991;32(1):55-62.
1990: Olov Wiklund; Germán Camejo; L Mattsson; F Lopez; Göran Bondjers
Cationic polypeptides modulate in vitro association of low density lipoprotein with arterial proteoglycans, fibroblasts, and arterial tissue.
Arteriosclerosis (Dallas, Tex.) 1990;10(5):695-702.
1990: Eva Hurt-Camejo; Germán Camejo; Birgitta Rosengren; F Lopez; Olov Wiklund; Göran Bondjers
Differential uptake of proteoglycan-selected subfractions of low density lipoprotein by human macrophages.
Journal of lipid research 1990;31(8):1387-98.
1990: Germán Camejo; Birgitta Rosengren; U Olson; F Lopez; S O Olofson; C Westerlund; Göran Bondjers
Molecular basis of the association of arterial proteoglycans with low density lipoproteins: its effect on the structure of the lipoprotein particle.
European heart journal 1990;11 Suppl E():164-73.
1990: Göran Bondjers; Olov Wiklund; Gunnar Fager; E H Camejo; Germán Camejo
Transfer of lipoproteins from plasma to the cell populations of the normal and atherosclerotic arterial tissue.
European heart journal 1990;11 Suppl E():158-63.
1990: Gunnar Fager; Henrik Semb; Sven Enerbäck; Thomas Olivecrona; L Jonasson; G Bengtsson-Olivecrona; Germán Camejo; Gunnar Bjursell; Göran Bondjers
Hyperlipoproteinemia type I in a patient with active lipoprotein lipase in adipose tissue and indications of defective transport of the enzyme.
Journal of lipid research 1990;31(7):1187-97.
1990: E Hurt; Göran Bondjers; Germán Camejo
Interaction of LDL with human arterial proteoglycans stimulates its uptake by human monocyte-derived macrophages.
Journal of lipid research 1990;31(3):443-54.
1990: T Lindén; Germán Camejo; Olov Wiklund; I Warnold; Sven-Olof Olofsson; Göran Bondjers
Effect of short-term beta blockade on serum lipid levels and on the interaction of LDL with human arterial proteoglycans.
Journal of clinical pharmacology 1990;30(2 Suppl):S124-31.
1990: Göran Bondjers; Germán Camejo; Gunnar Fager
The role of smooth muscle proliferation in atherogenesis.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1990;199():33-6.
1989: Germán Camejo; Birgitta Rosengren; Urban Olsson; Göran Bondjers
Agarose isoelectric focusing of plasma low and very low density lipoproteins using the PhastSystem.
Analytical biochemistry 1989;182(1):94-7.
1989: Germán Camejo; T Linden; Urban Olsson; Olov Wiklund; F Lopez; Göran Bondjers
Binding parameters and concentration modulate formation of complexes between LDL and arterial proteoglycans in serum.
Atherosclerosis 1989;79(2-3):121-8.
1989: T Linden; Göran Bondjers; Germán Camejo; R Bergstrand; L Wilhelmsen; Olov Wiklund
Affinity of LDL to a human arterial proteoglycan among male survivors of myocardial infarction.
European journal of clinical investigation 1989;19(1):38-44.
1988: Germán Camejo; Sven-Olof Olofsson; F Lopez; P Carlsson; Göran Bondjers
Identification of Apo B-100 segments mediating the interaction of low density lipoproteins with arterial proteoglycans.
Arteriosclerosis (Dallas, Tex.) 1988;8(4):368-77.
1987: E Hurt; Germán Camejo
Effect of arterial proteoglycans on the interaction of LDL with human monocyte-derived macrophages.
Atherosclerosis 1987;67(2-3):115-26.
1987: E Hurt; Manuel Velasco; H Silva; Germán Camejo
Effect of prazosin and propranolol on lipoproteins of hypertensive patients.
Biomedica biochimica acta 1987;46(1):111-8.
1986: Manuel Velasco; E Hurt; H Silva; A Urbina-Quintana; O Hernández-Pieretti; E Feldstein; Germán Camejo
Effects of prazosin and propranolol on blood lipids and lipoproteins in hypertensive patients.
The American journal of medicine 1986;80(2A):109-13.
1985: Germán Camejo; E Hurt; M Romano
Properties of lipoprotein complexes isolated by affinity chromatography from human aorta.
Biomedica biochimica acta 1985;44(3):389-401.
1983: Germán Camejo; E Ponce; F López; R Starosta; E Hurt; M Romano
Partial structure of the active moiety of a lipoprotein complexing proteoglycan from human aorta.
Atherosclerosis 1983;49(3):241-54.
1980: Germán Camejo; H Acquatella; F Lalaguna
The interaction of low density lipoproteins with arterial proteoglycans. An additional risk factor?
Atherosclerosis 1980;36(1):55-65.
1980: Germán Camejo; F Lalaguna; F López; R Starosta
Characterization and properties of a lipoprotein-complexing proteoglycan from human aorta.
Atherosclerosis 1980;35(3):307-20.