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lidia Boffa

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Anatomy

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lidia Boffa; Paola Menichini; Claudia Bolognesi; Giovanna Cutrona; silvio Roncella; Gianluca Damonte; Enrico Millo; Maria Rita Mariani; Serena Matis; D Russo; P Ciliutti; Manlio Ferrarini
Lack of mutagenicity and clastogenicity of PNAEmu-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma.
lidia Boffa; Giovanna Cutrona; Michele Cilli; Serena Matis; Gianluca Damonte; Maria Rita Mariani; Enrico Millo; M Moroni; silvio Roncella; Franco Fedeli; Manlio Ferrarini
Inhibition of Burkitt's lymphoma cells growth in SCID mice by a PNA specific for a regulatory sequence of the translocated c-myc.
Giovanna Cutrona; lidia Boffa; Maria Rita Mariani; Serena Matis; Gianluca Damonte; Enrico Millo; silvio Roncella; Manlio Ferrarini
The peptide nucleic acid targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma lacks immunogenicity: follow-up characterization of PNAEmu-NLS.

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All Publications

2007: lidia Boffa; Paola Menichini; Claudia Bolognesi; Giovanna Cutrona; silvio Roncella; Gianluca Damonte; Enrico Millo; Maria Rita Mariani; Serena Matis; D Russo; P Ciliutti; Manlio Ferrarini
Lack of mutagenicity and clastogenicity of PNAEmu-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma.
Mutation research 2007;628(2):129-37.
2007: lidia Boffa; Giovanna Cutrona; Michele Cilli; Serena Matis; Gianluca Damonte; Maria Rita Mariani; Enrico Millo; M Moroni; silvio Roncella; Franco Fedeli; Manlio Ferrarini
Inhibition of Burkitt's lymphoma cells growth in SCID mice by a PNA specific for a regulatory sequence of the translocated c-myc.
Cancer gene therapy 2007;14(2):220-6.
2007: Giovanna Cutrona; lidia Boffa; Maria Rita Mariani; Serena Matis; Gianluca Damonte; Enrico Millo; silvio Roncella; Manlio Ferrarini
The peptide nucleic acid targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma lacks immunogenicity: follow-up characterization of PNAEmu-NLS.
Oligonucleotides 2007;17(1):146-50.
2005: lidia Boffa; Giovanna Cutrona; Michele Cilli; Maria Rita Mariani; Serena Matis; Martina Pastorino; Gianluca Damonte; Enrico Millo; silvio Roncella; Manlio Ferrarini
Therapeutically promising PNA complementary to a regulatory sequence for c-myc: pharmacokinetics in an animal model of human Burkitt's lymphoma.
Oligonucleotides 2005;15(2):85-93.
2003: Giovanna Cutrona; Elisabetta M Carpaneto; Anna Ponzanelli; Massimo Ulivi; Enrico Millo; Sonia Scarfì; silvio Roncella; Umberto Benatti; lidia Boffa; Manlio Ferrarini
Inhibition of the translocated c-myc in Burkitt's lymphoma by a PNA complementary to the E mu enhancer.
Cancer research 2003;63(19):6144-8.
2003: Maria Rita Mariani; Elisabetta M Carpaneto; Massimo Ulivi; Vincent G Allfrey; lidia Boffa
Correlation between butyrate-induced histone hyperacetylation turn-over and c-myc expression.
The Journal of steroid biochemistry and molecular biology 2003;86(2):167-71.
2002: Giovanna Cutrona; P Tasso; Mariella Dono; silvio Roncella; Massimo Ulivi; Elisabetta M Carpaneto; V Fontana; M Comis; Fortunato Morabito; M Spinelli; E Frascella; lidia Boffa; G Basso; Vito Pistoia; Manlio Ferrarini
CD10 is a marker for cycling cells with propensity to apoptosis in childhood ALL.
British journal of cancer 2002;86(11):1776-85.
2001: Roberto P Stock; Alejandro Olvera; Ricardo Sánchez; Andrés Saralegui; Sonia Scarfì; Rosana Sanchez-Lopez; Marco Antonio Ramos; lidia Boffa; Umberto Benatti; Alejandro Alagón
Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers.
Nature biotechnology 2001;19(3):231-4.
2000: Roberto P Stock; Alejandro Olvera; Sonia Scarfì; Ricardo Sánchez; Marco Antonio Ramos; lidia Boffa; Umberto Benatti; O Landt; Alejandro Alagón
Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers.
Archives of medical research 2000;31(4 Suppl):S271-2.
2000: lidia Boffa; Sonia Scarfi; Maria Rita Mariani; Gianluca Damonte; Vincent G Allfrey; Umberto Benatti; P L Morris
Dihydrotestosterone as a selective cellular/nuclear localization vector for anti-gene peptide nucleic acid in prostatic carcinoma cells.
Cancer research 2000;60(8):2258-62.
2000: Giovanna Cutrona; Elisabetta M Carpaneto; Massimo Ulivi; silvio Roncella; O Landt; Manlio Ferrarini; lidia Boffa
Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal.
Nature biotechnology 2000;18(3):300-3.
1997: lidia Boffa; Elisabetta M Carpaneto; Maria Rita Mariani; M Louissaint; Vincent G Allfrey
Contrasting effects of PNA invasion of the chimeric DMMYC gene on transcription of its myc and PVT domains.
Oncology research 1997;9(1):41-51.
1996: lidia Boffa; P L Morris; E M Carpaneto; M Louissaint; V G Allfrey
Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence.
The Journal of biological chemistry 1996;271(22):13228-33.
1995: lidia Boffa; E M Carpaneto; V G Allfrey
Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):1901-5.
1994: lidia Boffa; M R Mariani; M I Parker
Selective hypermethylation of transcribed nucleosomal DNA by sodium butyrate.
Experimental cell research 1994;211(2):420-3.
1993: T A Chen-Cleland; lidia Boffa; E M Carpaneto; M R Mariani; E Valentin; E Mendez; V G Allfrey
Recovery of transcriptionally active chromatin restriction fragments by binding to organomercurial-agarose magnetic beads. A rapid and sensitive method for monitoring changes in higher order chromatin structure during gene activation and repression.
The Journal of biological chemistry 1993;268(31):23409-16.
1992: lidia Boffa; J R Lupton; M R Mariani; M Ceppi; H L Newmark; A Scalmati; M Lipkin
Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats.
Cancer research 1992;52(21):5906-12.
1992: lidia Boffa; M R Mariani; E M Carpaneto
Effects of N-methyl-N-nitrosourea on transcriptionally active and inactive nucleosomes: macromolecular damage and DNA repair.
Molecular carcinogenesis 1992;5(3):174-7.
1990: lidia Boffa; J Walker; T A Chen; R Sterner; M R Mariani; V G Allfrey
Factors affecting nucleosome structure in transcriptionally active chromatin. Histone acetylation, nascent RNA and inhibitors of RNA synthesis.
European journal of biochemistry / FEBS 1990;194(3):811-23.
1988: Claudia Bolognesi; M R Mariani; lidia Boffa
Target tissue DNA damage in inbred mouse strains with different susceptibility to the colon carcinogen 1,2-dimethylhydrazine.
Carcinogenesis 1988;9(8):1347-50.
1987: R Sterner; lidia Boffa; T A Chen; V G Allfrey
Cell cycle-dependent changes in conformation and composition of nucleosomes containing human histone gene sequences.
Nucleic acids research 1987;15(11):4375-91.
1987: lidia Boffa; Claudia Bolognesi; M R Mariani
Specific targets of alkylating agents in nuclear proteins of cultured hepatocytes.
Mutation research 1987;190(2):119-23.
1986: lidia Boffa; Claudia Bolognesi
In vitro DNA and nuclear proteins alkylation by 1,2-dimethylhydrazine.
Mutation research 1986;173(3):157-62.
1986: Claudia Bolognesi; lidia Boffa
Correlation between incidence of 1,2-dimethylhydrazine-induced colon carcinomas and DNA damage in six genetically different mouse strains.
Cancer letters 1986;30(1):91-5.
1985: lidia Boffa; Claudia Bolognesi
Nuclear proteins damage by alkylating agents with different degrees of carcinogenicity.
Chemico-biological interactions 1985;55(1-2):235-45.
1985: lidia Boffa; Claudia Bolognesi
Methylating agents: their target amino acids in nuclear proteins.
Carcinogenesis 1985;6(9):1399-401.
1982: lidia Boffa; R J Gruss; V G Allfrey
Aberrant and nonrandom methylation of chromosomal DNA-binding proteins of colonic epithelial cells by 1,2-dimethylhydrazine.
Cancer research 1982;42(2):382-8.
1981: lidia Boffa; R J Gruss; V G Allfrey
Manifold effects of sodium butyrate on nuclear function. Selective and reversible inhibition of phosphorylation of histones H1 and H2A and impaired methylation of lysine and arginine residues in nuclear protein fractions.
The Journal of biological chemistry 1981;256(18):9612-21.
1981: lidia Boffa; S Kozak; V G Allfrey
Activation of sodium cyanate for selective inhibition of protein synthesis in cultured tumor cells.
Cancer research 1981;41(1):60-6.
1980: lidia Boffa; B A Diwan; R Gruss; V G Allfrey
Differences in colonic nuclear proteins of two mouse strains with different susceptibilities to 1, 2-dimethylhydrazine-induced carcinogenesis.
Cancer research 1980;40(6):1774-80.
1979: lidia Boffa; R Sterner; G Vidali; V G Allfrey
Post-synthetic modifications of nuclear proteins. High mobility group proteins are methylated.
Biochemical and biophysical research communications 1979;89(4):1322-7.
1978: R Sterner; lidia Boffa; G Vidali
Comparative structural analysis of high mobility group proteins from a variety of sources. Evidence for a high mobility group protein unique to avian erythrocyte nuclei.
The Journal of biological chemistry 1978;253(11):3830-6.
1978: lidia Boffa; G Vidali; R S Mann; V G Allfrey
Suppression of histone deacetylation in vivo and in vitro by sodium butyrate.
The Journal of biological chemistry 1978;253(10):3364-6.
1978: G Vidali; lidia Boffa; R S Mann; V G Allfrey
Reversible effects of Na-butyrate on histone acetylation.
Biochemical and biophysical research communications 1978;82(1):223-7.
1978: G Vidali; lidia Boffa; E M Bradbury; V G Allfrey
Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(5):2239-43.
1977: V G Allfrey; lidia Boffa; G Vidali
Selective inhibition with sodium cyanate of protein synthesis in colon cancer cells.
Cancer 1977;40(5 Suppl):2692-8.
1977: lidia Boffa; V G Allfrey
Changes in chromosomal proteins in colon cancer: the complexity and DNA-binding properties of tumor-associated proteins and evidence for their association with the malignant state in human colonic epithelium.
Cancer 1977;40(5 Suppl):2584-91.
1977: J Karn; G Vidali; lidia Boffa; V G Allfrey
Characterization of the non-histone nuclear proteins associated with rapidly labeled heterogeneous nuclear RNA.
The Journal of biological chemistry 1977;252(20):7307-22.
1977: G Vidali; lidia Boffa; V G Allfrey
Selective release of chromosomal proteins during limited DNAase 1 digestion of avian erythrocyte chromatin.
Cell 1977;12(2):409-15.
1977: lidia Boffa; J Karn; G Vidali; V G Allfrey
Distribution of NG, NG,-dimethylarginine in nuclear protein fractions.
Biochemical and biophysical research communications 1977;74(3):969-76.
1976: lidia Boffa; V G Allfrey
Characteristic complements of nuclear nonhistone proteins in colonic epithelial tumors.
Cancer research 1976;36(7 PT 2):2678-85.
1976: lidia Boffa; G Vidali; V G Allfrey
Changes in nuclear non-histone protein composition during normal differentiation and carcinogenesis of intestinal epithelial cells.
Experimental cell research 1976;98(2):396-410.
1975: lidia Boffa; G Vidali; V G Allfrey
Selective synthesis and accumulation of nuclear non-histone proteins during carcinogenesis of the colon induced by 1, 2-dimethylhydrazine.
Cancer 1975;36(6 Suppl):2356-63.
1973: G Vidali; lidia Boffa; V C Littau; K M Allfrey; V G Allfrey
Changes in nuclear acidic protein complement of red blood cells during embryonic development.
The Journal of biological chemistry 1973;248(11):4065-8.
1972: G Vidali; lidia Boffa; V G Allfrey
Properties of an acidic histone-binding protein fraction from cell nuclei. Selective precipitation and deacetylation of histones F2A1 and F3.
The Journal of biological chemistry 1972;247(22):7365-73.
1971: lidia Boffa; E L Gershey; G Vidali
Changes of the histone deacetylase activity during chick embryo muscle development.
Biochimica et biophysica acta 1971;254(1):135-43.
1971: lidia Boffa; G Vidali
Acid-extractable proteins from chick embryo muscle nuclei. Characterization of histone and studies on histone acetylation.
Biochimica et biophysica acta 1971;236(1):259-69.